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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for AAGGUGC

Z-value: 0.59

Motif logo

miRNA associated with seed AAGGUGC

NamemiRBASE accession
MIMAT0000072
MIMAT0001412
MIMAT0019861

Activity profile of AAGGUGC motif

Sorted Z-values of AAGGUGC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AAGGUGC

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_234952009 8.75 ENST00000392011.7
SH3 domain binding protein 4
chr3_-_123884290 7.16 ENST00000346322.9
ENST00000360772.7
ENST00000360304.8
myosin light chain kinase
chr3_+_107522936 5.53 ENST00000415149.6
ENST00000402543.5
ENST00000325805.13
ENST00000427402.5
BBX high mobility group box domain containing
chr14_+_61695777 5.40 ENST00000323441.10
hypoxia inducible factor 1 subunit alpha
chr6_-_131951364 4.89 ENST00000367976.4
cellular communication network factor 2
chr7_-_121396284 4.33 ENST00000359943.8
ENST00000426156.1
ENST00000412653.5
FAM3 metabolism regulating signaling molecule C
chr2_+_36355712 4.22 ENST00000280527.7
cysteine rich transmembrane BMP regulator 1
chr15_+_39581068 4.22 ENST00000397591.2
ENST00000260356.6
thrombospondin 1
chr21_-_17612842 4.12 ENST00000339775.10
ENST00000348354.7
BTG anti-proliferation factor 3
chr3_+_172040554 4.04 ENST00000336824.8
ENST00000423424.5
fibronectin type III domain containing 3B
chr1_-_202808406 3.51 ENST00000650569.1
ENST00000367265.9
ENST00000649770.1
lysine demethylase 5B
chr3_-_115071333 3.47 ENST00000462705.5
zinc finger and BTB domain containing 20
chr7_+_66921217 3.16 ENST00000341567.8
ENST00000607045.5
transmembrane protein 248
chr6_+_133953210 3.01 ENST00000367869.1
ENST00000237264.9
ENST00000674115.1
TATA-box binding protein like 1
novel protein
chr2_-_25878445 2.82 ENST00000336112.9
ENST00000435504.9
ASXL transcriptional regulator 2
chr3_-_185825029 2.79 ENST00000382199.7
insulin like growth factor 2 mRNA binding protein 2
chr3_+_105366877 2.69 ENST00000306107.9
activated leukocyte cell adhesion molecule
chr4_-_156971769 2.65 ENST00000502773.6
platelet derived growth factor C
chr2_+_84971093 2.57 ENST00000456682.1
ENST00000409785.9
potassium channel modulatory factor 1
chr19_+_3572927 2.50 ENST00000333651.11
ENST00000417382.5
high mobility group 20B
chr15_-_55917129 2.42 ENST00000338963.6
ENST00000508342.5
NEDD4 E3 ubiquitin protein ligase
chr17_-_42154916 2.32 ENST00000592574.1
ENST00000550406.1
ENST00000547517.5
ENST00000346213.9
ENST00000393860.7
novel protein
RAB5C, member RAS oncogene family
chr9_-_71768386 2.29 ENST00000377066.9
ENST00000377044.9
cell migration inducing hyaluronidase 2
chr5_-_143403611 2.20 ENST00000394464.7
ENST00000231509.7
nuclear receptor subfamily 3 group C member 1
chr9_-_136050502 2.09 ENST00000371753.5
NACC family member 2
chr2_+_12716893 2.05 ENST00000381465.2
ENST00000155926.9
tribbles pseudokinase 2
chr3_-_113746218 1.73 ENST00000497255.1
ENST00000240922.8
ENST00000478020.1
ENST00000493900.5
N-alpha-acetyltransferase 50, NatE catalytic subunit
chr1_-_120069616 1.72 ENST00000652302.1
ENST00000652737.1
ENST00000256646.7
notch receptor 2
chrX_+_13689116 1.60 ENST00000464506.2
ENST00000243325.6
RAB9A, member RAS oncogene family
chr1_-_50960230 1.57 ENST00000396153.7
Fas associated factor 1
chr17_+_48908397 1.53 ENST00000360943.10
ubiquitin conjugating enzyme E2 Z
chr3_+_152299392 1.44 ENST00000498502.5
ENST00000545754.5
ENST00000357472.7
ENST00000324196.9
muscleblind like splicing regulator 1
chr6_+_39792993 1.43 ENST00000538976.5
dishevelled associated activator of morphogenesis 2
chr1_+_36155930 1.42 ENST00000316156.8
MAP7 domain containing 1
chr12_+_12611839 1.33 ENST00000228865.3
cAMP responsive element binding protein like 2
chr6_-_16761447 1.33 ENST00000244769.8
ENST00000436367.6
ataxin 1
chr1_-_94541746 1.22 ENST00000334047.12
coagulation factor III, tissue factor
chr1_-_162023826 1.21 ENST00000294794.8
olfactomedin like 2B
chr6_-_11232658 1.09 ENST00000379433.5
ENST00000379446.10
ENST00000620854.4
neural precursor cell expressed, developmentally down-regulated 9
chr2_+_46698909 1.07 ENST00000650611.1
ENST00000306503.5
long intergenic non-protein coding RNA 1118
suppressor of cytokine signaling 5
chr6_-_85642922 0.95 ENST00000616122.5
ENST00000678618.1
ENST00000678816.1
ENST00000676630.1
ENST00000678589.1
ENST00000678878.1
ENST00000676542.1
ENST00000355238.11
ENST00000678899.1
synaptotagmin binding cytoplasmic RNA interacting protein
chr14_+_51989609 0.93 ENST00000556760.5
RNA transcription, translation and transport factor
chr10_-_689613 0.91 ENST00000280886.12
ENST00000634311.1
disco interacting protein 2 homolog C
chr9_+_122941003 0.88 ENST00000373647.9
ENST00000402311.5
RAB GTPase activating protein 1
chr1_+_87328860 0.85 ENST00000370544.10
LIM domain only 4
chr1_+_173714908 0.85 ENST00000209884.5
kelch like family member 20
chr3_+_37861926 0.83 ENST00000443503.6
CTD small phosphatase like
chr12_-_43806249 0.82 ENST00000548315.5
ENST00000552521.5
ENST00000546662.5
ENST00000548403.1
ENST00000546506.5
ENST00000395510.7
twinfilin actin binding protein 1
chr16_-_85688912 0.75 ENST00000253462.8
GINS complex subunit 2
chr2_-_152175715 0.71 ENST00000263904.5
signal transducing adaptor molecule 2
chr9_-_125189721 0.65 ENST00000456642.1
ENST00000373547.9
ENST00000415905.5
ENST00000451402.5
protein phosphatase 6 catalytic subunit
chr17_+_50346099 0.61 ENST00000017003.7
ENST00000509778.1
ENST00000507602.5
xylosyltransferase 2
chr4_+_182243394 0.59 ENST00000511685.6
teneurin transmembrane protein 3
chr20_+_58309704 0.57 ENST00000244040.4
RAB22A, member RAS oncogene family
chr4_-_184474518 0.50 ENST00000393593.8
interferon regulatory factor 2
chr10_+_70815889 0.46 ENST00000373202.8
sphingosine-1-phosphate lyase 1
chr18_-_47930630 0.43 ENST00000262160.11
SMAD family member 2
chr10_-_70170466 0.42 ENST00000373239.2
ENST00000373241.9
ENST00000373242.6
secretion associated Ras related GTPase 1A
chr12_+_109097568 0.42 ENST00000242576.7
uracil DNA glycosylase
chr20_+_32277626 0.38 ENST00000375712.4
kinesin family member 3B
chr9_+_93576557 0.36 ENST00000359246.9
ENST00000375376.8
PHD finger protein 2
chr9_+_88388356 0.36 ENST00000375859.4
spindlin 1
chr17_-_64263221 0.32 ENST00000258991.7
ENST00000583738.1
ENST00000584379.6
testis expressed 2
chr10_-_118046922 0.32 ENST00000355624.8
RAB11 family interacting protein 2
chr18_+_22933819 0.31 ENST00000399722.6
ENST00000399725.6
ENST00000399721.6
RB binding protein 8, endonuclease
chr3_-_33440343 0.30 ENST00000283629.8
upstream binding protein 1
chr5_-_74640719 0.30 ENST00000302351.9
ENST00000509127.2
ectodermal-neural cortex 1
chr9_+_116153783 0.28 ENST00000328252.4
pappalysin 1
chr14_+_55051639 0.27 ENST00000395468.9
ENST00000622254.1
mitogen-activated protein kinase 1 interacting protein 1 like
chr5_-_79512794 0.26 ENST00000282260.10
ENST00000508576.5
ENST00000535690.1
homer scaffold protein 1
chr12_+_55966821 0.25 ENST00000553376.5
ENST00000440311.6
ENST00000266970.9
ENST00000354056.4
cyclin dependent kinase 2
chr2_+_28392802 0.25 ENST00000379619.5
ENST00000264716.9
FOS like 2, AP-1 transcription factor subunit
chr11_-_34357994 0.23 ENST00000435224.3
ankyrin repeat and BTB domain containing 2
chr20_+_5126988 0.23 ENST00000460006.6
CDP-diacylglycerol synthase 2
chr12_+_104064520 0.21 ENST00000229330.9
host cell factor C2
chr1_-_108963413 0.17 ENST00000676454.1
ENST00000675790.1
ENST00000674849.1
ENST00000675956.1
ENST00000369976.5
ENST00000675584.1
ENST00000302500.5
ENST00000356970.6
ENST00000676392.1
ENST00000676059.1
ENST00000675571.1
ENST00000675018.1
ENST00000674527.1
ENST00000369968.7
ENST00000369969.7
ENST00000675508.1
ENST00000675650.1
ENST00000369970.8
ENST00000675654.1
ENST00000357393.6
chloride channel CLIC like 1
AKNA domain containing 1
chr2_-_200963633 0.16 ENST00000234296.7
origin recognition complex subunit 2
chr10_-_79445617 0.16 ENST00000372336.4
zinc finger CCHC-type containing 24
chr6_+_137867414 0.15 ENST00000237289.8
ENST00000433680.1
TNF alpha induced protein 3
chr11_+_95089804 0.15 ENST00000278505.5
endonuclease domain containing 1
chr16_-_17470953 0.11 ENST00000261381.7
xylosyltransferase 1
chr1_+_84078043 0.11 ENST00000370689.6
ENST00000370688.7
protein kinase cAMP-activated catalytic subunit beta
chr2_+_24491860 0.08 ENST00000406961.5
ENST00000405141.5
nuclear receptor coactivator 1
chr15_+_73052449 0.07 ENST00000261908.11
neogenin 1
chr16_+_30949054 0.07 ENST00000318663.5
ENST00000566237.1
ENST00000562699.1
ORAI calcium release-activated calcium modulator 3
chr11_-_79441016 0.07 ENST00000278550.12
teneurin transmembrane protein 4
chrX_+_109536832 0.07 ENST00000372106.6
nuclear transport factor 2 like export factor 2
chr5_+_31193678 0.06 ENST00000265071.3
cadherin 6
chr16_-_74607088 0.06 ENST00000565260.1
ENST00000447066.6
ENST00000205061.9
ENST00000422840.7
ENST00000627032.2
golgi glycoprotein 1
chr5_+_103258747 0.05 ENST00000319933.7
macrophage immunometabolism regulator
chr12_+_54549586 0.05 ENST00000243052.8
phosphodiesterase 1B
chr2_-_55419565 0.05 ENST00000647341.1
ENST00000647401.1
ENST00000336838.10
ENST00000621814.4
ENST00000644033.1
ENST00000645477.1
ENST00000647517.1
coiled-coil domain containing 88A
chr1_-_37859583 0.03 ENST00000373036.5
metal regulatory transcription factor 1
chr10_+_110007964 0.03 ENST00000277900.12
ENST00000356080.9
adducin 3
chr1_+_99969979 0.02 ENST00000427993.7
ENST00000533028.8
ENST00000639221.1
ENST00000638336.1
ENST00000639807.1
ENST00000640715.1
ENST00000465289.6
ENST00000639994.1
ENST00000638988.1
ENST00000640732.1
ENST00000640600.1
ENST00000638338.1
ENST00000638792.1
ENST00000639037.1
solute carrier family 35 member A3
novel protein
chr5_+_108747879 0.01 ENST00000281092.9
FER tyrosine kinase
chr6_+_16238554 0.01 ENST00000259727.5
guanosine monophosphate reductase
chr10_+_100535927 0.00 ENST00000299163.7
hypoxia inducible factor 1 subunit alpha inhibitor

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:0010752 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) regulation of cGMP-mediated signaling(GO:0010752)
1.2 7.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.9 5.4 GO:0070101 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.8 2.4 GO:0044007 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
0.7 3.5 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.5 2.1 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.5 3.0 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.3 1.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.3 2.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2 2.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.2 2.8 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.2 1.7 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 0.8 GO:0030047 actin modification(GO:0030047)
0.2 1.6 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405)
0.2 8.8 GO:0043090 amino acid import(GO:0043090)
0.2 1.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.2 2.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 0.4 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.1 1.7 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 2.5 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.8 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 1.6 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 2.6 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 0.4 GO:0061188 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1 2.7 GO:1902284 axon extension involved in axon guidance(GO:0048846) neuron projection extension involved in neuron projection guidance(GO:1902284)
0.1 4.2 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.1 0.7 GO:0097264 self proteolysis(GO:0097264)
0.1 0.8 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 0.9 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.1 0.3 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 3.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 0.6 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.2 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427) regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of osteoclast proliferation(GO:0090291)
0.1 0.3 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.5 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.3 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.4 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.8 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.0 0.4 GO:0045008 depyrimidination(GO:0045008)
0.0 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.7 GO:0036258 multivesicular body assembly(GO:0036258)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 2.8 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 0.1 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 1.3 GO:0046326 positive regulation of glucose import(GO:0046326)
0.0 4.5 GO:0002576 platelet degranulation(GO:0002576)
0.0 4.6 GO:0060348 bone development(GO:0060348)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 1.4 GO:0045445 myoblast differentiation(GO:0045445)
0.0 0.6 GO:0007032 endosome organization(GO:0007032)
0.0 0.9 GO:1902017 regulation of cilium assembly(GO:1902017)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.2 GO:0005577 fibrinogen complex(GO:0005577)
0.3 1.3 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.2 1.7 GO:0031415 NatA complex(GO:0031415)
0.2 2.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.2 0.7 GO:0033565 ESCRT-0 complex(GO:0033565)
0.2 4.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.2 0.8 GO:0000811 GINS complex(GO:0000811)
0.1 0.4 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.9 GO:0097452 GAIT complex(GO:0097452)
0.1 7.2 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.6 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 5.4 GO:1904115 axon cytoplasm(GO:1904115)
0.1 2.7 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.3 GO:0097135 X chromosome(GO:0000805) cyclin E2-CDK2 complex(GO:0097135)
0.1 8.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 2.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 2.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.2 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.0 0.4 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 1.2 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 2.3 GO:0005811 lipid particle(GO:0005811)
0.0 2.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.6 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 3.8 GO:0005819 spindle(GO:0005819)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 7.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.4 4.2 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
1.4 4.2 GO:0070052 collagen V binding(GO:0070052)
0.7 3.5 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.7 3.9 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.5 1.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.3 2.4 GO:0050815 phosphoserine binding(GO:0050815)
0.3 8.8 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 0.7 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.2 1.3 GO:0034046 poly(G) binding(GO:0034046)
0.2 2.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 2.1 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 2.6 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.1 1.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 5.4 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 4.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 2.8 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.4 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.1 4.5 GO:0019003 GDP binding(GO:0019003)
0.1 0.8 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 1.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 1.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.4 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.0 0.9 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.5 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.4 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.3 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 3.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 4.3 GO:0005125 cytokine activity(GO:0005125)
0.0 0.3 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.3 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.1 GO:0039706 co-receptor binding(GO:0039706)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 7.2 PID AURORA B PATHWAY Aurora B signaling
0.1 4.2 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 2.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 2.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 4.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.7 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.8 PID BMP PATHWAY BMP receptor signaling
0.0 1.1 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.8 PID IL6 7 PATHWAY IL6-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 5.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 1.7 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 2.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 7.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.1 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 2.0 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 4.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.2 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 2.3 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 2.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 3.0 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 3.1 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 2.2 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex