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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for AAGUGCU

Z-value: 0.43

Motif logo

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miRNA associated with seed AAGUGCU

NamemiRBASE accession
hsa-miR-302a-3p
MIMAT0000684
hsa-miR-302b-3p
MIMAT0000715
hsa-miR-302c-3p.1
MIMAT0000717
hsa-miR-302d-3p
MIMAT0000718
hsa-miR-302e
MIMAT0005931
hsa-miR-372-3p
MIMAT0000724
hsa-miR-373-3p
MIMAT0000726
hsa-miR-520a-3p
MIMAT0002834
hsa-miR-520b
MIMAT0002843
hsa-miR-520c-3p
MIMAT0002846
hsa-miR-520d-3p
MIMAT0002856
hsa-miR-520e
MIMAT0002825

Activity profile of AAGUGCU motif

Sorted Z-values of AAGUGCU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AAGUGCU

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr8_-_66613208 5.24 ENST00000522677.8
MYBL1
MYB proto-oncogene like 1
chr12_-_44875647 4.33 ENST00000395487.6
NELL2
neural EGFL like 2
chr11_+_118530990 4.01 ENST00000411589.6
ENST00000359862.8
ENST00000442938.6
TMEM25
transmembrane protein 25
chr6_+_11537738 3.83 ENST00000379426.2
TMEM170B
transmembrane protein 170B
chr14_-_99272184 3.60 ENST00000357195.8
BCL11B
BAF chromatin remodeling complex subunit BCL11B
chr16_+_19113955 3.12 ENST00000381440.5
ENST00000564808.6
ENST00000568526.1
ITPRIPL2
ENSG00000261427.6
ITPRIP like 2
novel transcript
chr8_+_42896883 3.00 ENST00000307602.9
HOOK3
hook microtubule tethering protein 3
chrX_+_16719595 2.87 ENST00000380155.4
SYAP1
synapse associated protein 1
chr19_+_16197900 2.85 ENST00000429941.6
ENST00000291439.8
ENST00000444449.6
ENST00000589822.5
AP1M1
adaptor related protein complex 1 subunit mu 1
chr10_-_27240743 2.83 ENST00000677901.1
ENST00000677960.1
ENST00000677440.1
ENST00000396271.8
ENST00000677141.1
ENST00000677311.1
ENST00000677667.1
ENST00000677200.1
ENST00000676997.1
ENST00000676511.1
ACBD5
acyl-CoA binding domain containing 5
chr14_-_59630582 2.68 ENST00000395090.5
RTN1
reticulon 1
chr3_+_43286512 2.53 ENST00000454177.5
ENST00000429705.6
ENST00000296088.12
ENST00000437827.1
SNRK
SNF related kinase
chr4_-_108168919 2.48 ENST00000265165.6
LEF1
lymphoid enhancer binding factor 1
chr5_+_72107453 2.40 ENST00000296755.12
ENST00000511641.2
MAP1B
microtubule associated protein 1B
chr2_-_96145431 2.18 ENST00000288943.5
DUSP2
dual specificity phosphatase 2
chr8_-_81112055 2.03 ENST00000220597.4
PAG1
phosphoprotein membrane anchor with glycosphingolipid microdomains 1
chr5_-_44389407 2.01 ENST00000264664.5
FGF10
fibroblast growth factor 10
chr4_-_82798735 1.98 ENST00000273908.4
ENST00000319540.9
SCD5
stearoyl-CoA desaturase 5
chr17_-_42745025 1.91 ENST00000592492.5
ENST00000585893.5
ENST00000593214.5
ENST00000590078.5
ENST00000428826.7
ENST00000586382.5
ENST00000415827.6
ENST00000592743.5
ENST00000586089.5
EZH1
enhancer of zeste 1 polycomb repressive complex 2 subunit
chr6_+_125790922 1.88 ENST00000453302.5
ENST00000417494.5
ENST00000392477.7
ENST00000229634.13
NCOA7
nuclear receptor coactivator 7
chr3_-_50567646 1.87 ENST00000426034.5
ENST00000441239.5
C3orf18
chromosome 3 open reading frame 18
chr22_+_29073024 1.85 ENST00000400335.9
KREMEN1
kringle containing transmembrane protein 1
chr12_+_119593758 1.82 ENST00000426426.3
TMEM233
transmembrane protein 233
chr6_+_41072939 1.80 ENST00000341376.11
ENST00000353205.5
NFYA
nuclear transcription factor Y subunit alpha
chr10_-_118754956 1.78 ENST00000369151.8
CACUL1
CDK2 associated cullin domain 1
chr1_+_226223618 1.78 ENST00000542034.5
ENST00000366810.6
MIXL1
Mix paired-like homeobox
chrX_+_111096136 1.77 ENST00000372007.10
PAK3
p21 (RAC1) activated kinase 3
chr6_-_154356735 1.75 ENST00000367220.8
ENST00000265198.8
ENST00000520261.1
IPCEF1
interaction protein for cytohesin exchange factors 1
chr17_+_7281711 1.71 ENST00000317370.13
ENST00000571308.5
SLC2A4
solute carrier family 2 member 4
chr9_-_127980976 1.68 ENST00000373095.6
FAM102A
family with sequence similarity 102 member A
chr11_-_132943671 1.67 ENST00000331898.11
OPCML
opioid binding protein/cell adhesion molecule like
chr1_-_235328147 1.66 ENST00000264183.9
ENST00000418304.1
ENST00000349213.7
ARID4B
AT-rich interaction domain 4B
chrX_+_23334841 1.64 ENST00000379361.5
PTCHD1
patched domain containing 1
chr17_-_50130121 1.64 ENST00000330175.9
SAMD14
sterile alpha motif domain containing 14
chr7_-_20217342 1.62 ENST00000400331.10
ENST00000332878.8
MACC1
MET transcriptional regulator MACC1
chr3_-_12967668 1.61 ENST00000273221.8
IQSEC1
IQ motif and Sec7 domain ArfGEF 1
chr9_-_83956677 1.61 ENST00000376344.8
C9orf64
chromosome 9 open reading frame 64
chr16_-_53503192 1.59 ENST00000568596.5
ENST00000394657.12
ENST00000570004.5
ENST00000564497.1
ENST00000300245.8
AKTIP
AKT interacting protein
chr20_+_58309704 1.55 ENST00000244040.4
RAB22A
RAB22A, member RAS oncogene family
chr2_-_234497035 1.52 ENST00000390645.2
ENST00000339728.6
ARL4C
ADP ribosylation factor like GTPase 4C
chr1_-_225889143 1.51 ENST00000272134.5
LEFTY1
left-right determination factor 1
chr14_-_44961889 1.49 ENST00000579157.1
ENST00000396128.9
ENST00000556500.1
KLHL28
kelch like family member 28
chr21_-_31558977 1.48 ENST00000286827.7
ENST00000541036.5
TIAM1
TIAM Rac1 associated GEF 1
chr22_+_39994926 1.48 ENST00000333407.11
FAM83F
family with sequence similarity 83 member F
chr20_-_4823597 1.44 ENST00000379400.8
RASSF2
Ras association domain family member 2
chr11_+_118436464 1.42 ENST00000389506.10
ENST00000534358.8
ENST00000531904.6
ENST00000649699.1
KMT2A
lysine methyltransferase 2A
chr7_-_44885446 1.36 ENST00000395699.5
PURB
purine rich element binding protein B
chr6_+_87155537 1.36 ENST00000369577.8
ENST00000518845.1
ENST00000339907.8
ENST00000496806.2
ZNF292
zinc finger protein 292
chr3_+_20040437 1.34 ENST00000263754.5
KAT2B
lysine acetyltransferase 2B
chr1_-_24964984 1.33 ENST00000338888.3
ENST00000399916.5
RUNX3
RUNX family transcription factor 3
chr15_+_68578970 1.33 ENST00000261861.10
CORO2B
coronin 2B
chr12_+_4909895 1.33 ENST00000638821.1
ENST00000382545.5
ENSG00000256654.4
KCNA1
novel transcript, sense overlapping KCNA1
potassium voltage-gated channel subfamily A member 1
chr20_-_49278034 1.32 ENST00000371744.5
ENST00000396105.6
ENST00000371752.5
ZNFX1
zinc finger NFX1-type containing 1
chr12_+_67648737 1.31 ENST00000344096.4
ENST00000393555.3
DYRK2
dual specificity tyrosine phosphorylation regulated kinase 2
chr7_+_77696423 1.31 ENST00000334955.13
RSBN1L
round spermatid basic protein 1 like
chr6_-_142946312 1.27 ENST00000367604.6
HIVEP2
HIVEP zinc finger 2
chr1_-_230426293 1.27 ENST00000391860.7
PGBD5
piggyBac transposable element derived 5
chr5_-_115180037 1.26 ENST00000514154.1
ENST00000282369.7
TRIM36
tripartite motif containing 36
chr1_+_244051275 1.22 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr2_+_197804583 1.19 ENST00000428675.6
PLCL1
phospholipase C like 1 (inactive)
chr2_+_29115367 1.19 ENST00000320081.10
CLIP4
CAP-Gly domain containing linker protein family member 4
chr9_-_109167159 1.18 ENST00000561981.5
FRRS1L
ferric chelate reductase 1 like
chr2_+_69829630 1.17 ENST00000282570.4
GMCL1
germ cell-less 1, spermatogenesis associated
chr1_+_84078043 1.17 ENST00000370689.6
ENST00000370688.7
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr3_+_179347686 1.16 ENST00000471841.6
MFN1
mitofusin 1
chr6_-_32128191 1.16 ENST00000453203.2
ENST00000375203.8
ENST00000375201.8
ATF6B
activating transcription factor 6 beta
chr2_+_26848093 1.15 ENST00000288699.11
DPYSL5
dihydropyrimidinase like 5
chr6_-_89118002 1.15 ENST00000452027.3
SRSF12
serine and arginine rich splicing factor 12
chr1_-_20486197 1.14 ENST00000375078.4
CAMK2N1
calcium/calmodulin dependent protein kinase II inhibitor 1
chr15_-_61229297 1.13 ENST00000335670.11
RORA
RAR related orphan receptor A
chr2_-_25878445 1.13 ENST00000336112.9
ENST00000435504.9
ASXL2
ASXL transcriptional regulator 2
chr11_+_129375841 1.13 ENST00000281437.6
BARX2
BARX homeobox 2
chr12_+_72272360 1.12 ENST00000547300.2
ENST00000261180.10
TRHDE
thyrotropin releasing hormone degrading enzyme
chr4_+_44678412 1.12 ENST00000281543.6
GUF1
GTP binding elongation factor GUF1
chr4_+_85475131 1.10 ENST00000395184.6
ARHGAP24
Rho GTPase activating protein 24
chr17_-_5234801 1.10 ENST00000571800.5
ENST00000574081.6
ENST00000399600.8
ENST00000574297.1
SCIMP
SLP adaptor and CSK interacting membrane protein
chr13_+_51584435 1.09 ENST00000612477.1
ENST00000298125.7
WDFY2
WD repeat and FYVE domain containing 2
chr10_+_124801799 1.07 ENST00000298492.6
ABRAXAS2
abraxas 2, BRISC complex subunit
chr9_-_23821275 1.07 ENST00000380110.8
ELAVL2
ELAV like RNA binding protein 2
chr16_-_2135898 1.06 ENST00000262304.9
ENST00000423118.5
PKD1
polycystin 1, transient receptor potential channel interacting
chr9_+_79571767 1.06 ENST00000376544.7
TLE4
TLE family member 4, transcriptional corepressor
chr8_-_19013693 1.06 ENST00000327040.13
PSD3
pleckstrin and Sec7 domain containing 3
chr14_-_92040027 1.06 ENST00000267622.8
TRIP11
thyroid hormone receptor interactor 11
chr7_-_5781594 1.05 ENST00000416985.5
ENST00000389902.8
ENST00000425013.6
RNF216
ring finger protein 216
chr1_-_226737277 1.04 ENST00000272117.7
ITPKB
inositol-trisphosphate 3-kinase B
chr1_-_207051202 1.03 ENST00000315927.9
YOD1
YOD1 deubiquitinase
chr8_+_28494190 1.02 ENST00000537916.2
ENST00000240093.8
ENST00000523546.1
FZD3
frizzled class receptor 3
chr9_-_16870662 1.01 ENST00000380672.9
BNC2
basonuclin 2
chr10_+_61901678 1.00 ENST00000644638.1
ENST00000681100.1
ENST00000279873.12
ARID5B
AT-rich interaction domain 5B
chr15_+_31326807 0.99 ENST00000307145.4
KLF13
Kruppel like factor 13
chr7_-_32891744 0.98 ENST00000304056.9
KBTBD2
kelch repeat and BTB domain containing 2
chr1_+_3690654 0.98 ENST00000378285.5
ENST00000378280.5
ENST00000378288.8
TP73
tumor protein p73
chr7_+_139341311 0.95 ENST00000297534.7
ENST00000541515.3
FMC1
FMC1-LUC7L2
formation of mitochondrial complex V assembly factor 1 homolog
FMC1-LUC7L2 readthrough
chr7_+_139359846 0.95 ENST00000619796.4
ENST00000354926.9
LUC7L2
LUC7 like 2, pre-mRNA splicing factor
chr15_-_83284645 0.92 ENST00000345382.7
BNC1
basonuclin 1
chr3_-_18425295 0.92 ENST00000338745.11
ENST00000450898.1
SATB1
SATB homeobox 1
chr15_-_78234513 0.92 ENST00000558130.1
ENST00000258873.9
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr12_+_8032692 0.91 ENST00000162391.8
FOXJ2
forkhead box J2
chr1_+_209827964 0.90 ENST00000491415.7
UTP25
UTP25 small subunit processor component
chr20_+_62143729 0.89 ENST00000331758.8
ENST00000450482.5
SS18L1
SS18L1 subunit of BAF chromatin remodeling complex
chr1_-_225941383 0.88 ENST00000420304.6
LEFTY2
left-right determination factor 2
chr4_+_74308463 0.88 ENST00000413830.6
EPGN
epithelial mitogen
chr9_-_19102887 0.87 ENST00000380502.8
HAUS6
HAUS augmin like complex subunit 6
chr12_-_56189548 0.87 ENST00000347471.8
ENST00000267064.8
ENST00000394023.7
SMARCC2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2
chr1_-_113812448 0.86 ENST00000612242.4
ENST00000261441.9
RSBN1
round spermatid basic protein 1
chr12_-_16608183 0.86 ENST00000354662.5
ENST00000538051.5
LMO3
LIM domain only 3
chr10_+_135067 0.85 ENST00000381591.5
ZMYND11
zinc finger MYND-type containing 11
chr8_-_52714414 0.84 ENST00000435644.6
ENST00000518710.5
ENST00000025008.10
ENST00000517963.1
RB1CC1
RB1 inducible coiled-coil 1
chr1_-_55215345 0.84 ENST00000294383.7
USP24
ubiquitin specific peptidase 24
chr3_-_56801939 0.84 ENST00000296315.8
ENST00000495373.5
ARHGEF3
Rho guanine nucleotide exchange factor 3
chr1_-_47231715 0.83 ENST00000371884.6
TAL1
TAL bHLH transcription factor 1, erythroid differentiation factor
chr8_-_42051978 0.82 ENST00000265713.8
ENST00000648335.1
ENST00000485568.5
ENST00000426524.6
ENST00000396930.4
ENST00000406337.6
KAT6A
lysine acetyltransferase 6A
chr5_+_149730260 0.81 ENST00000360453.8
ENST00000394320.7
ENST00000309241.10
PPARGC1B
PPARG coactivator 1 beta
chr5_-_175444132 0.81 ENST00000393752.3
DRD1
dopamine receptor D1
chr17_-_68291116 0.80 ENST00000327268.8
ENST00000580666.6
SLC16A6
solute carrier family 16 member 6
chr3_-_197749688 0.80 ENST00000273582.9
RUBCN
rubicon autophagy regulator
chr1_+_28369705 0.79 ENST00000373839.8
PHACTR4
phosphatase and actin regulator 4
chr11_-_73598183 0.78 ENST00000064778.8
FAM168A
family with sequence similarity 168 member A
chr10_+_72215981 0.76 ENST00000615507.4
ENST00000621663.4
ENST00000299381.5
ANAPC16
anaphase promoting complex subunit 16
chr7_+_87345656 0.75 ENST00000331536.8
ENST00000419147.6
ENST00000412227.6
CROT
carnitine O-octanoyltransferase
chr11_-_77820706 0.74 ENST00000440064.2
ENST00000528095.5
ENST00000308488.11
RSF1
remodeling and spacing factor 1
chr21_+_45643694 0.74 ENST00000400314.5
PCBP3
poly(rC) binding protein 3
chr7_+_120273129 0.73 ENST00000331113.9
KCND2
potassium voltage-gated channel subfamily D member 2
chr7_-_142885737 0.73 ENST00000359396.9
ENST00000436401.1
TRPV6
transient receptor potential cation channel subfamily V member 6
chr2_-_181680490 0.73 ENST00000684145.1
ENST00000295108.4
ENST00000684079.1
ENST00000683430.1
CERKL
NEUROD1
ceramide kinase like
neuronal differentiation 1
chr2_-_69643703 0.72 ENST00000406297.7
ENST00000409085.9
AAK1
AP2 associated kinase 1
chr7_+_20330893 0.72 ENST00000222573.5
ITGB8
integrin subunit beta 8
chr4_-_52659238 0.70 ENST00000451218.6
ENST00000441222.8
USP46
ubiquitin specific peptidase 46
chr12_+_55966821 0.70 ENST00000553376.5
ENST00000440311.6
ENST00000266970.9
ENST00000354056.4
CDK2
cyclin dependent kinase 2
chr17_+_49788672 0.70 ENST00000454930.6
ENST00000259021.9
ENST00000509773.5
ENST00000510819.5
ENST00000424009.6
KAT7
lysine acetyltransferase 7
chr11_-_62727444 0.70 ENST00000301785.7
HNRNPUL2
heterogeneous nuclear ribonucleoprotein U like 2
chr17_-_49764123 0.69 ENST00000240364.7
ENST00000506156.1
FAM117A
family with sequence similarity 117 member A
chr17_+_44187027 0.69 ENST00000587989.1
ENST00000590235.5
TMUB2
transmembrane and ubiquitin like domain containing 2
chr12_-_122526929 0.69 ENST00000331738.12
ENST00000528279.1
ENST00000344591.8
ENST00000526560.6
RSRC2
arginine and serine rich coiled-coil 2
chr7_+_65873068 0.69 ENST00000360768.5
VKORC1L1
vitamin K epoxide reductase complex subunit 1 like 1
chr18_-_47930630 0.67 ENST00000262160.11
SMAD2
SMAD family member 2
chr2_-_196171565 0.67 ENST00000263955.9
STK17B
serine/threonine kinase 17b
chr18_+_34978244 0.66 ENST00000436190.6
MAPRE2
microtubule associated protein RP/EB family member 2
chr9_+_36036899 0.65 ENST00000377966.4
RECK
reversion inducing cysteine rich protein with kazal motifs
chr14_+_35046238 0.65 ENST00000280987.9
FAM177A1
family with sequence similarity 177 member A1
chr11_-_68213277 0.65 ENST00000401547.6
ENST00000304363.9
ENST00000453170.5
KMT5B
lysine methyltransferase 5B
chrX_+_134373297 0.64 ENST00000332070.7
ENST00000370803.8
ENST00000625464.2
ENST00000370799.5
PHF6
PHD finger protein 6
chr2_-_102736819 0.64 ENST00000258436.10
MFSD9
major facilitator superfamily domain containing 9
chr2_-_23927107 0.64 ENST00000238789.10
ATAD2B
ATPase family AAA domain containing 2B
chr12_-_95073580 0.63 ENST00000393101.7
ENST00000333003.10
ENST00000622476.4
NR2C1
nuclear receptor subfamily 2 group C member 1
chr17_-_58517835 0.63 ENST00000579921.1
ENST00000579925.5
ENST00000323456.9
MTMR4
myotubularin related protein 4
chr1_-_175743529 0.63 ENST00000367674.7
ENST00000263525.6
TNR
tenascin R
chr9_-_37465402 0.63 ENST00000307750.5
ZBTB5
zinc finger and BTB domain containing 5
chr20_-_37095985 0.62 ENST00000344359.7
ENST00000373664.8
RBL1
RB transcriptional corepressor like 1
chr10_+_91220603 0.62 ENST00000336126.6
PCGF5
polycomb group ring finger 5
chr14_+_52267683 0.62 ENST00000306051.3
ENST00000553372.1
PTGDR
prostaglandin D2 receptor
chr16_-_4273014 0.62 ENST00000204517.11
TFAP4
transcription factor AP-4
chr2_-_73113018 0.62 ENST00000258098.6
RAB11FIP5
RAB11 family interacting protein 5
chr11_+_61752603 0.61 ENST00000278836.10
MYRF
myelin regulatory factor
chr5_+_96936071 0.60 ENST00000231368.10
LNPEP
leucyl and cystinyl aminopeptidase
chr8_-_73878816 0.59 ENST00000602593.6
ENST00000651945.1
ENST00000419880.7
ENST00000517608.5
ENST00000650817.1
UBE2W
ubiquitin conjugating enzyme E2 W
chr11_-_108593738 0.59 ENST00000525344.5
ENST00000265843.9
EXPH5
exophilin 5
chr13_+_21671067 0.59 ENST00000382353.6
FGF9
fibroblast growth factor 9
chr6_+_108166015 0.59 ENST00000368986.9
NR2E1
nuclear receptor subfamily 2 group E member 1
chr14_+_56579782 0.58 ENST00000261556.11
ENST00000538838.5
TMEM260
transmembrane protein 260
chr3_-_15065240 0.58 ENST00000449354.6
ENST00000253686.7
ENST00000444840.6
MRPS25
mitochondrial ribosomal protein S25
chr11_+_33257265 0.57 ENST00000303296.9
ENST00000379016.7
HIPK3
homeodomain interacting protein kinase 3
chr11_+_67119245 0.57 ENST00000529006.7
ENST00000398645.6
KDM2A
lysine demethylase 2A
chr7_+_100015588 0.57 ENST00000324306.11
ENST00000426572.5
ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr3_+_10164883 0.56 ENST00000256458.5
IRAK2
interleukin 1 receptor associated kinase 2
chr20_+_32277626 0.55 ENST00000375712.4
KIF3B
kinesin family member 3B
chr17_+_75721451 0.55 ENST00000200181.8
ITGB4
integrin subunit beta 4
chr9_-_135907509 0.55 ENST00000389532.9
CAMSAP1
calmodulin regulated spectrin associated protein 1
chr8_-_27772585 0.54 ENST00000522915.5
ENST00000356537.9
CCDC25
coiled-coil domain containing 25
chr8_-_56211257 0.54 ENST00000316981.8
ENST00000423799.6
ENST00000429357.2
PLAG1
PLAG1 zinc finger
chr2_-_239400949 0.54 ENST00000345617.7
HDAC4
histone deacetylase 4
chr12_-_57742120 0.54 ENST00000257897.7
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr9_-_122913299 0.52 ENST00000373659.4
ZBTB6
zinc finger and BTB domain containing 6
chr2_+_238426920 0.52 ENST00000264607.9
ASB1
ankyrin repeat and SOCS box containing 1
chr1_-_205631962 0.52 ENST00000289703.8
ENST00000357992.9
ELK4
ETS transcription factor ELK4
chr3_-_101677119 0.52 ENST00000312938.5
ZBTB11
zinc finger and BTB domain containing 11
chr15_-_65517244 0.51 ENST00000341861.9
DPP8
dipeptidyl peptidase 8
chr8_-_59119121 0.50 ENST00000361421.2
TOX
thymocyte selection associated high mobility group box
chr15_-_45187955 0.50 ENST00000560471.5
ENST00000560540.5
SHF
Src homology 2 domain containing F
chr10_+_100535927 0.50 ENST00000299163.7
HIF1AN
hypoxia inducible factor 1 subunit alpha inhibitor
chr14_+_103334176 0.50 ENST00000560338.5
ENST00000560763.5
ENST00000216554.8
EIF5
eukaryotic translation initiation factor 5
chr8_+_28890365 0.49 ENST00000519662.5
ENST00000558662.5
ENST00000287701.15
ENST00000523613.5
ENST00000560599.5
ENST00000397358.7
HMBOX1
homeobox containing 1
chr1_-_84690406 0.49 ENST00000605755.5
ENST00000342203.8
ENST00000437941.6
SSX2IP
SSX family member 2 interacting protein
chr2_-_73269483 0.48 ENST00000295133.9
FBXO41
F-box protein 41
chr2_-_24047348 0.47 ENST00000406895.3
WDCP
WD repeat and coiled coil containing
chr2_+_15940537 0.47 ENST00000281043.4
ENST00000638417.1
MYCN
MYCN proto-oncogene, bHLH transcription factor
chr3_+_138187248 0.47 ENST00000538260.5
ENST00000481646.5
ENST00000491704.5
ENST00000469044.6
ENST00000461600.5
ENST00000466749.5
ENST00000358441.6
ENST00000489213.5
ARMC8
armadillo repeat containing 8
chr10_+_14878848 0.46 ENST00000433779.5
ENST00000378325.7
ENST00000354919.11
ENST00000313519.9
ENST00000420416.1
SUV39H2
suppressor of variegation 3-9 homolog 2
chr3_+_15206179 0.45 ENST00000253693.7
CAPN7
calpain 7
chr9_+_126805003 0.45 ENST00000449886.5
ENST00000450858.1
ENST00000373464.5
ZBTB43
zinc finger and BTB domain containing 43
chr7_-_152435786 0.45 ENST00000682283.1
ENST00000679882.1
ENST00000452749.2
ENST00000683616.1
ENST00000262189.11
ENST00000683490.1
ENST00000681082.1
ENST00000684550.1
KMT2C
lysine methyltransferase 2C
chr3_-_171460368 0.44 ENST00000436636.7
ENST00000465393.1
ENST00000341852.10
TNIK
TRAF2 and NCK interacting kinase
chr13_-_26221703 0.44 ENST00000381570.7
ENST00000346166.7
RNF6
ring finger protein 6
chr4_-_73258785 0.44 ENST00000639793.1
ENST00000358602.9
ENST00000330838.10
ENST00000561029.1
ANKRD17
ankyrin repeat domain 17
chr9_-_10612966 0.44 ENST00000381196.9
PTPRD
protein tyrosine phosphatase receptor type D
chr3_-_101320558 0.43 ENST00000193391.8
IMPG2
interphotoreceptor matrix proteoglycan 2
chr19_-_4066892 0.43 ENST00000322357.9
ZBTB7A
zinc finger and BTB domain containing 7A
chr6_-_154510675 0.43 ENST00000607772.6
CNKSR3
CNKSR family member 3
chr21_-_34888683 0.41 ENST00000344691.8
ENST00000358356.9
RUNX1
RUNX family transcription factor 1
chr10_+_1049476 0.41 ENST00000358220.5
WDR37
WD repeat domain 37

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.6 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.8 2.3 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.7 3.7 GO:0030242 pexophagy(GO:0030242)
0.6 2.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.5 3.0 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.5 2.5 GO:0071895 odontoblast differentiation(GO:0071895)
0.5 2.5 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.5 1.4 GO:2001025 positive regulation of response to drug(GO:2001025)
0.4 1.5 GO:1900147 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.3 1.0 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.3 1.3 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.3 4.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.3 1.4 GO:1904693 midbrain morphogenesis(GO:1904693)
0.3 0.8 GO:0030221 basophil differentiation(GO:0030221) positive regulation of chromatin assembly or disassembly(GO:0045799) astrocyte fate commitment(GO:0060018)
0.3 1.1 GO:0072237 metanephric proximal tubule development(GO:0072237)
0.3 0.8 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of autophagosome maturation(GO:1901097)
0.3 0.8 GO:0061386 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.3 0.8 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.2 1.3 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.2 0.8 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.2 0.6 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.2 1.2 GO:0097338 response to clozapine(GO:0097338)
0.2 1.7 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.2 0.7 GO:0072708 response to sorbitol(GO:0072708)
0.2 2.0 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.2 0.8 GO:0035106 operant conditioning(GO:0035106)
0.2 0.6 GO:0048690 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.1 1.0 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
0.1 0.4 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 2.9 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.1 2.4 GO:0061162 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.1 0.7 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 1.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.5 GO:0061428 peptidyl-aspartic acid hydroxylation(GO:0042264) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.1 0.4 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.1 1.5 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.4 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.7 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.2 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
0.1 2.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 1.2 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.9 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 1.1 GO:0021702 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 1.8 GO:0015671 oxygen transport(GO:0015671)
0.1 1.8 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 1.2 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 1.1 GO:0001955 blood vessel maturation(GO:0001955)
0.1 0.9 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 1.2 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.1 0.4 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.1 1.2 GO:0030238 male sex determination(GO:0030238)
0.1 0.3 GO:0003099 vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 1.0 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 1.6 GO:0021794 thalamus development(GO:0021794)
0.1 1.6 GO:0060004 reflex(GO:0060004)
0.1 1.9 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.1 1.7 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 1.8 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.4 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.7 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.1 0.6 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1 0.5 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.1 0.6 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.6 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 1.7 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.1 1.7 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.7 GO:0042373 vitamin K metabolic process(GO:0042373)
0.1 0.7 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.2 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.1 0.2 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1 0.2 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 2.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 1.4 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.5 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.7 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.9 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0035881 amacrine cell differentiation(GO:0035881)
0.0 0.4 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.4 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0 0.2 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.6 GO:0035878 nail development(GO:0035878)
0.0 0.4 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.6 GO:0071468 cellular response to acidic pH(GO:0071468)
0.0 0.2 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.7 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.0 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.0 0.5 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.3 GO:0021553 olfactory nerve development(GO:0021553)
0.0 1.1 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.6 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:2000836 androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.0 2.2 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 0.5 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 1.4 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.4 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.9 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.8 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 1.3 GO:0007340 acrosome reaction(GO:0007340)
0.0 1.5 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 1.3 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.0 0.3 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.4 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.4 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.8 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.6 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 1.8 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.5 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 1.1 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.0 1.6 GO:0006400 tRNA modification(GO:0006400)
0.0 0.7 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.6 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.4 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:0021800 cerebral cortex tangential migration(GO:0021800)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 1.0 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.1 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 1.1 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.2 GO:0046039 GTP metabolic process(GO:0046039)
0.0 1.1 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.2 GO:0034378 chylomicron assembly(GO:0034378)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 2.0 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.0 0.0 GO:0002537 nitric oxide production involved in inflammatory response(GO:0002537)
0.0 0.2 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.0 0.1 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 1.2 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 1.4 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 0.8 GO:0090398 cellular senescence(GO:0090398)
0.0 0.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.4 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.8 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.3 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 1.7 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 0.3 GO:0051568 histone H3-K4 methylation(GO:0051568)
0.0 0.5 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.3 GO:0071218 cellular response to misfolded protein(GO:0071218)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.6 GO:0070695 FHF complex(GO:0070695)
0.4 1.1 GO:0002079 inner acrosomal membrane(GO:0002079) outer acrosomal membrane(GO:0002081)
0.2 0.7 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.2 0.7 GO:0097135 X chromosome(GO:0000805) cyclin E2-CDK2 complex(GO:0097135)
0.2 0.6 GO:0016939 kinesin II complex(GO:0016939)
0.2 1.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 1.8 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.3 GO:0000125 PCAF complex(GO:0000125)
0.1 2.5 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.7 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.6 GO:0072534 perineuronal net(GO:0072534)
0.1 0.6 GO:0031905 early endosome lumen(GO:0031905)
0.1 1.1 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 1.2 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.1 0.9 GO:0070652 HAUS complex(GO:0070652)
0.1 0.6 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 0.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 0.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 1.4 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.8 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.7 GO:0031010 ISWI-type complex(GO:0031010)
0.1 0.4 GO:0070545 PeBoW complex(GO:0070545)
0.1 1.3 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.1 1.5 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.5 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 1.1 GO:0032433 filopodium tip(GO:0032433)
0.1 1.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.3 GO:0032302 MutSbeta complex(GO:0032302)
0.1 0.2 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0 2.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.2 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.9 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 1.4 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726) interchromatin granule(GO:0035061)
0.0 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.0 1.8 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 3.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.0 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.9 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.9 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 2.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.3 GO:0030681 multimeric ribonuclease P complex(GO:0030681)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.6 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 3.0 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.0 1.8 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.7 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0071546 pi-body(GO:0071546)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 1.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 2.3 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.2 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.2 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 1.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.5 2.0 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.5 2.0 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.5 1.4 GO:0045322 unmethylated CpG binding(GO:0045322)
0.5 5.0 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.4 1.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.3 1.0 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.2 1.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.2 0.8 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.2 1.1 GO:0008142 oxysterol binding(GO:0008142)
0.2 0.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 2.4 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 1.1 GO:0050733 RS domain binding(GO:0050733)
0.1 2.8 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.4 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 1.7 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.9 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 1.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.7 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.1 0.5 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.1 0.7 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.1 0.7 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.6 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 1.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 0.7 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.8 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 1.1 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.1 0.3 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.1 2.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 2.3 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 0.5 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.5 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.1 1.0 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 1.1 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 1.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 1.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.6 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.7 GO:0046625 sphingolipid binding(GO:0046625)
0.1 0.4 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 1.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.2 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.9 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.9 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.3 GO:0000406 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 1.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.2 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 0.6 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.5 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.7 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 1.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 0.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 4.6 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.7 GO:0035173 histone kinase activity(GO:0035173)
0.0 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.9 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.3 GO:0018812 3-hydroxyacyl-CoA dehydratase activity(GO:0018812)
0.0 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 1.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.3 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.4 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 1.3 GO:0030145 manganese ion binding(GO:0030145)
0.0 1.9 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.2 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.8 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.0 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 7.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402) peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 0.3 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.8 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 8.6 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.0 0.0 GO:0015181 L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 1.6 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) potassium ion antiporter activity(GO:0022821)
0.0 0.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 1.0 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 2.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 0.6 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.1 5.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 1.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 2.0 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 2.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 2.0 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 2.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.5 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.6 PID ARF6 PATHWAY Arf6 signaling events
0.0 2.0 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.8 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 3.0 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.3 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 3.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.9 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.9 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 1.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 2.6 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 3.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 2.0 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 1.7 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 0.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 0.6 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.6 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 2.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 2.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 1.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.1 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.4 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 1.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME TRAF6 MEDIATED NFKB ACTIVATION Genes involved in TRAF6 mediated NF-kB activation
0.0 0.3 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.0 0.3 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions