Project
avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for AAUACUG
Z-value: 2.64
Motif logo
miRNA associated with seed AAUACUG
| Name | miRBASE accession |
|---|---|
|
hsa-miR-200b-3p
|
MIMAT0000318 |
|
hsa-miR-200c-3p
|
MIMAT0000617 |
|
hsa-miR-429
|
MIMAT0001536 |
Activity profile of AAUACUG motif
Sorted Z-values of AAUACUG motif
Network of associatons between targets according to the STRING database.
First level regulatory network of AAUACUG
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.2 | 9.6 | GO:1901420 | negative regulation of response to alcohol(GO:1901420) |
| 3.1 | 12.2 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 3.0 | 11.9 | GO:0070358 | actin polymerization-dependent cell motility(GO:0070358) |
| 2.9 | 17.3 | GO:0022614 | membrane to membrane docking(GO:0022614) |
| 2.8 | 8.3 | GO:0016344 | meiotic chromosome movement towards spindle pole(GO:0016344) |
| 2.6 | 12.8 | GO:2001074 | regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076) |
| 2.3 | 6.9 | GO:0075732 | viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594) |
| 1.9 | 15.0 | GO:0015825 | L-serine transport(GO:0015825) |
| 1.9 | 1.9 | GO:0035802 | adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802) |
| 1.8 | 5.4 | GO:0034402 | recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402) |
| 1.7 | 12.1 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 1.7 | 5.2 | GO:0051365 | leading edge cell differentiation(GO:0035026) cellular response to potassium ion starvation(GO:0051365) |
| 1.7 | 5.0 | GO:0071676 | negative regulation of mononuclear cell migration(GO:0071676) |
| 1.6 | 4.8 | GO:0032707 | negative regulation of interleukin-23 production(GO:0032707) |
| 1.6 | 6.4 | GO:0003409 | optic cup structural organization(GO:0003409) |
| 1.5 | 6.1 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 1.5 | 7.4 | GO:0030035 | microspike assembly(GO:0030035) |
| 1.5 | 5.8 | GO:1990737 | response to manganese-induced endoplasmic reticulum stress(GO:1990737) |
| 1.4 | 5.7 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
| 1.4 | 8.5 | GO:0032328 | alanine transport(GO:0032328) |
| 1.4 | 4.1 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) |
| 1.4 | 9.6 | GO:0010724 | regulation of definitive erythrocyte differentiation(GO:0010724) |
| 1.4 | 4.1 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 1.4 | 12.3 | GO:1902902 | negative regulation of autophagosome assembly(GO:1902902) |
| 1.3 | 29.6 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 1.3 | 3.9 | GO:0008614 | pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819) |
| 1.3 | 5.1 | GO:0001519 | peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179) |
| 1.3 | 3.8 | GO:2000681 | negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687) |
| 1.3 | 16.4 | GO:0044387 | negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387) |
| 1.3 | 7.5 | GO:0097338 | response to clozapine(GO:0097338) |
| 1.2 | 8.4 | GO:2000643 | positive regulation of early endosome to late endosome transport(GO:2000643) |
| 1.2 | 3.5 | GO:0021897 | forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897) |
| 1.1 | 3.4 | GO:0044830 | modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254) |
| 1.1 | 3.2 | GO:1903033 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 1.0 | 3.1 | GO:0007174 | epidermal growth factor catabolic process(GO:0007174) |
| 1.0 | 4.0 | GO:2000393 | negative regulation of lamellipodium morphogenesis(GO:2000393) |
| 1.0 | 3.0 | GO:1901874 | negative regulation of post-translational protein modification(GO:1901874) |
| 1.0 | 3.0 | GO:0006679 | glucosylceramide biosynthetic process(GO:0006679) |
| 1.0 | 5.9 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 1.0 | 2.9 | GO:0034085 | establishment of sister chromatid cohesion(GO:0034085) regulation of chromosome condensation(GO:0060623) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
| 1.0 | 2.9 | GO:1901355 | response to rapamycin(GO:1901355) |
| 0.9 | 13.9 | GO:0000338 | protein deneddylation(GO:0000338) |
| 0.9 | 10.1 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.9 | 3.5 | GO:1903371 | regulation of endoplasmic reticulum tubular network organization(GO:1903371) |
| 0.9 | 16.3 | GO:0070831 | basement membrane assembly(GO:0070831) |
| 0.9 | 5.1 | GO:0008218 | bioluminescence(GO:0008218) |
| 0.9 | 6.0 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
| 0.8 | 6.8 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.8 | 9.9 | GO:1904903 | ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903) |
| 0.8 | 2.3 | GO:0060278 | regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
| 0.8 | 10.6 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.8 | 3.8 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 0.7 | 3.7 | GO:1902513 | regulation of organelle transport along microtubule(GO:1902513) |
| 0.7 | 3.0 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
| 0.7 | 3.0 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.7 | 2.1 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
| 0.7 | 6.2 | GO:0080182 | histone H3-K4 trimethylation(GO:0080182) |
| 0.7 | 6.2 | GO:0006335 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.7 | 5.4 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.7 | 2.6 | GO:0060339 | negative regulation of type I interferon-mediated signaling pathway(GO:0060339) |
| 0.7 | 2.0 | GO:1902309 | negative regulation of peptidyl-serine dephosphorylation(GO:1902309) |
| 0.6 | 3.7 | GO:0090625 | mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795) |
| 0.6 | 1.8 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
| 0.6 | 1.8 | GO:0060903 | regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of meiosis I(GO:0060903) |
| 0.6 | 2.9 | GO:0061083 | regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084) |
| 0.6 | 2.9 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 0.6 | 4.7 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 0.6 | 2.9 | GO:0030311 | poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311) |
| 0.6 | 6.9 | GO:0061339 | establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339) |
| 0.6 | 1.7 | GO:0072365 | regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365) |
| 0.6 | 1.7 | GO:0071335 | male genitalia morphogenesis(GO:0048808) submandibular salivary gland formation(GO:0060661) white fat cell proliferation(GO:0070343) positive regulation of fat cell proliferation(GO:0070346) regulation of white fat cell proliferation(GO:0070350) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338) male anatomical structure morphogenesis(GO:0090598) |
| 0.6 | 5.0 | GO:0060613 | fat pad development(GO:0060613) |
| 0.6 | 3.3 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.5 | 4.4 | GO:0034436 | glycoprotein transport(GO:0034436) |
| 0.5 | 5.4 | GO:2000189 | positive regulation of cholesterol homeostasis(GO:2000189) |
| 0.5 | 2.0 | GO:0046833 | positive regulation of RNA export from nucleus(GO:0046833) |
| 0.5 | 7.9 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.5 | 10.8 | GO:0032780 | negative regulation of ATPase activity(GO:0032780) |
| 0.5 | 1.0 | GO:0010735 | positive regulation of transcription via serum response element binding(GO:0010735) |
| 0.5 | 4.4 | GO:0090394 | negative regulation of excitatory postsynaptic potential(GO:0090394) |
| 0.5 | 10.2 | GO:0042532 | negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532) |
| 0.5 | 3.3 | GO:0070341 | fat cell proliferation(GO:0070341) regulation of fat cell proliferation(GO:0070344) negative regulation of fat cell proliferation(GO:0070345) |
| 0.5 | 2.4 | GO:0003056 | regulation of vascular smooth muscle contraction(GO:0003056) negative regulation of vasoconstriction(GO:0045906) |
| 0.5 | 20.5 | GO:0035329 | hippo signaling(GO:0035329) |
| 0.5 | 4.2 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 0.5 | 6.9 | GO:1900119 | positive regulation of execution phase of apoptosis(GO:1900119) |
| 0.4 | 1.3 | GO:0071373 | cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373) |
| 0.4 | 2.2 | GO:1904566 | response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566) |
| 0.4 | 3.8 | GO:1902037 | negative regulation of hematopoietic stem cell differentiation(GO:1902037) |
| 0.4 | 3.7 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.4 | 2.1 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 0.4 | 1.2 | GO:2000832 | negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850) |
| 0.4 | 1.1 | GO:0021764 | amygdala development(GO:0021764) |
| 0.4 | 1.1 | GO:0048149 | behavioral response to ethanol(GO:0048149) |
| 0.4 | 1.5 | GO:0030806 | negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) |
| 0.4 | 1.5 | GO:0051586 | peptidyl-cysteine methylation(GO:0018125) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) |
| 0.4 | 2.9 | GO:0042256 | mature ribosome assembly(GO:0042256) positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651) |
| 0.4 | 2.1 | GO:1904016 | response to Thyroglobulin triiodothyronine(GO:1904016) |
| 0.3 | 1.4 | GO:2000325 | regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327) |
| 0.3 | 1.7 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) |
| 0.3 | 4.0 | GO:0042407 | cristae formation(GO:0042407) |
| 0.3 | 2.6 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.3 | 2.6 | GO:0060373 | regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) |
| 0.3 | 2.9 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.3 | 3.1 | GO:0001514 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.3 | 1.5 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
| 0.3 | 0.9 | GO:0035509 | negative regulation of myosin-light-chain-phosphatase activity(GO:0035509) negative regulation of bicellular tight junction assembly(GO:1903347) |
| 0.3 | 3.3 | GO:0021740 | trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795) |
| 0.3 | 4.4 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.3 | 3.5 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.3 | 1.7 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
| 0.3 | 1.4 | GO:0043652 | engulfment of apoptotic cell(GO:0043652) |
| 0.3 | 2.7 | GO:0072718 | response to cisplatin(GO:0072718) |
| 0.3 | 2.2 | GO:0033211 | adiponectin-activated signaling pathway(GO:0033211) |
| 0.3 | 2.7 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.3 | 1.3 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
| 0.2 | 1.7 | GO:0048312 | intracellular distribution of mitochondria(GO:0048312) |
| 0.2 | 1.9 | GO:0007379 | segment specification(GO:0007379) |
| 0.2 | 8.8 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
| 0.2 | 1.6 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
| 0.2 | 3.8 | GO:0071545 | inositol phosphate catabolic process(GO:0071545) |
| 0.2 | 1.6 | GO:0006688 | glycosphingolipid biosynthetic process(GO:0006688) |
| 0.2 | 1.7 | GO:0006477 | protein sulfation(GO:0006477) heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
| 0.2 | 1.0 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 0.2 | 1.0 | GO:0044821 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 0.2 | 0.8 | GO:0010917 | negative regulation of mitochondrial membrane potential(GO:0010917) |
| 0.2 | 3.2 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 0.2 | 1.0 | GO:0035522 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) |
| 0.2 | 0.4 | GO:0051461 | regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461) |
| 0.2 | 2.4 | GO:0007097 | nuclear migration(GO:0007097) |
| 0.2 | 2.6 | GO:0021957 | corticospinal tract morphogenesis(GO:0021957) |
| 0.2 | 5.1 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.2 | 7.9 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.2 | 3.9 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.2 | 2.3 | GO:0032968 | positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968) |
| 0.2 | 2.2 | GO:0010944 | negative regulation of transcription by competitive promoter binding(GO:0010944) |
| 0.2 | 3.5 | GO:0033622 | integrin activation(GO:0033622) |
| 0.1 | 3.9 | GO:0021591 | ventricular system development(GO:0021591) |
| 0.1 | 0.6 | GO:0035750 | protein localization to myelin sheath abaxonal region(GO:0035750) |
| 0.1 | 2.0 | GO:0060117 | auditory receptor cell development(GO:0060117) |
| 0.1 | 0.7 | GO:0030174 | regulation of DNA-dependent DNA replication initiation(GO:0030174) |
| 0.1 | 1.1 | GO:0098814 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
| 0.1 | 0.9 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) |
| 0.1 | 1.1 | GO:2000587 | negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587) |
| 0.1 | 0.4 | GO:0051939 | gamma-aminobutyric acid import(GO:0051939) |
| 0.1 | 1.8 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.1 | 1.6 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 0.1 | 3.1 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.1 | 0.6 | GO:0042986 | positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) |
| 0.1 | 0.9 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.1 | 8.2 | GO:0006301 | postreplication repair(GO:0006301) |
| 0.1 | 0.2 | GO:0048633 | positive regulation of skeletal muscle tissue growth(GO:0048633) |
| 0.1 | 6.8 | GO:0019835 | cytolysis(GO:0019835) |
| 0.1 | 0.4 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 0.1 | 0.3 | GO:2000620 | innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620) |
| 0.1 | 0.7 | GO:0035093 | spermatogenesis, exchange of chromosomal proteins(GO:0035093) |
| 0.1 | 0.8 | GO:0045176 | apical protein localization(GO:0045176) |
| 0.1 | 2.0 | GO:0070734 | histone H3-K27 methylation(GO:0070734) |
| 0.1 | 0.5 | GO:0090206 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 0.1 | 1.6 | GO:2000785 | regulation of autophagosome assembly(GO:2000785) |
| 0.1 | 2.7 | GO:0043555 | regulation of translation in response to stress(GO:0043555) |
| 0.1 | 3.5 | GO:0070328 | acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328) |
| 0.1 | 1.5 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.1 | 8.3 | GO:0048208 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
| 0.1 | 0.6 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
| 0.1 | 1.4 | GO:0061158 | 3'-UTR-mediated mRNA destabilization(GO:0061158) |
| 0.1 | 0.7 | GO:0042271 | susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
| 0.1 | 1.6 | GO:0051923 | sulfation(GO:0051923) |
| 0.1 | 2.9 | GO:0017004 | cytochrome complex assembly(GO:0017004) |
| 0.1 | 1.0 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
| 0.1 | 1.1 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 0.1 | 2.3 | GO:0000185 | activation of MAPKKK activity(GO:0000185) |
| 0.1 | 1.1 | GO:0006449 | regulation of translational termination(GO:0006449) |
| 0.1 | 1.0 | GO:0042659 | regulation of cell fate specification(GO:0042659) |
| 0.1 | 5.3 | GO:0042267 | natural killer cell mediated cytotoxicity(GO:0042267) |
| 0.1 | 0.7 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.1 | 3.8 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.1 | 1.4 | GO:0007020 | microtubule nucleation(GO:0007020) |
| 0.1 | 6.5 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.1 | 0.4 | GO:0033031 | positive regulation of neutrophil apoptotic process(GO:0033031) |
| 0.1 | 0.9 | GO:0046628 | positive regulation of insulin receptor signaling pathway(GO:0046628) |
| 0.1 | 1.5 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.1 | 4.5 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
| 0.1 | 0.2 | GO:2000653 | regulation of genetic imprinting(GO:2000653) |
| 0.1 | 2.1 | GO:0031643 | positive regulation of myelination(GO:0031643) |
| 0.1 | 1.0 | GO:0061051 | positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051) |
| 0.1 | 0.2 | GO:0070316 | regulation of G0 to G1 transition(GO:0070316) |
| 0.1 | 2.3 | GO:0048745 | smooth muscle tissue development(GO:0048745) |
| 0.1 | 3.5 | GO:0046949 | fatty-acyl-CoA biosynthetic process(GO:0046949) |
| 0.1 | 6.8 | GO:0030316 | osteoclast differentiation(GO:0030316) |
| 0.1 | 1.7 | GO:0030514 | negative regulation of BMP signaling pathway(GO:0030514) |
| 0.1 | 0.2 | GO:0098908 | regulation of neuronal action potential(GO:0098908) |
| 0.1 | 6.0 | GO:0032392 | DNA geometric change(GO:0032392) |
| 0.1 | 1.8 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.1 | 3.2 | GO:0021762 | substantia nigra development(GO:0021762) |
| 0.1 | 4.6 | GO:0051893 | regulation of focal adhesion assembly(GO:0051893) regulation of cell-substrate junction assembly(GO:0090109) |
| 0.1 | 0.5 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
| 0.1 | 0.8 | GO:0071340 | skeletal muscle acetylcholine-gated channel clustering(GO:0071340) |
| 0.1 | 3.7 | GO:0006446 | regulation of translational initiation(GO:0006446) |
| 0.1 | 6.3 | GO:1900034 | regulation of cellular response to heat(GO:1900034) |
| 0.1 | 1.5 | GO:0006625 | protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
| 0.0 | 0.7 | GO:0006044 | N-acetylglucosamine metabolic process(GO:0006044) |
| 0.0 | 1.1 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.0 | 0.5 | GO:0060385 | axonogenesis involved in innervation(GO:0060385) |
| 0.0 | 1.6 | GO:0051437 | positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437) |
| 0.0 | 0.9 | GO:0042753 | positive regulation of circadian rhythm(GO:0042753) |
| 0.0 | 1.0 | GO:0044872 | lipoprotein transport(GO:0042953) lipoprotein localization(GO:0044872) |
| 0.0 | 1.0 | GO:0007143 | female meiotic division(GO:0007143) |
| 0.0 | 0.3 | GO:0010807 | regulation of synaptic vesicle priming(GO:0010807) |
| 0.0 | 0.4 | GO:0006122 | mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122) |
| 0.0 | 1.2 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
| 0.0 | 0.3 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.0 | 0.9 | GO:0050855 | regulation of B cell receptor signaling pathway(GO:0050855) |
| 0.0 | 2.6 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.0 | 0.5 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.0 | 1.1 | GO:0071549 | cellular response to dexamethasone stimulus(GO:0071549) |
| 0.0 | 0.7 | GO:0033197 | response to vitamin E(GO:0033197) |
| 0.0 | 2.0 | GO:0019886 | antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886) |
| 0.0 | 1.1 | GO:0048009 | insulin-like growth factor receptor signaling pathway(GO:0048009) |
| 0.0 | 2.0 | GO:0042255 | ribosome assembly(GO:0042255) |
| 0.0 | 0.6 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
| 0.0 | 0.2 | GO:0001712 | ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712) |
| 0.0 | 12.3 | GO:0043687 | post-translational protein modification(GO:0043687) |
| 0.0 | 1.3 | GO:0001756 | somitogenesis(GO:0001756) |
| 0.0 | 3.1 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.0 | 15.0 | GO:0030036 | actin cytoskeleton organization(GO:0030036) |
| 0.0 | 0.0 | GO:1903625 | regulation of deoxyribonuclease activity(GO:0032070) negative regulation of DNA catabolic process(GO:1903625) |
| 0.0 | 0.2 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
| 0.0 | 0.3 | GO:0018345 | protein palmitoylation(GO:0018345) |
| 0.0 | 0.3 | GO:0015074 | DNA integration(GO:0015074) |
| 0.0 | 0.3 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.0 | 0.5 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
| 0.0 | 0.1 | GO:0032808 | lacrimal gland development(GO:0032808) |
| 0.0 | 0.4 | GO:2000300 | regulation of synaptic vesicle exocytosis(GO:2000300) |
| 0.0 | 0.2 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.0 | 1.3 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.0 | 0.3 | GO:2000637 | positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637) |
| 0.0 | 0.1 | GO:0002084 | protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734) |
| 0.0 | 4.1 | GO:0010608 | posttranscriptional regulation of gene expression(GO:0010608) |
| 0.0 | 0.7 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.0 | 0.5 | GO:0046039 | GTP metabolic process(GO:0046039) |
| 0.0 | 0.2 | GO:0043403 | skeletal muscle tissue regeneration(GO:0043403) |
| 0.0 | 0.2 | GO:0017145 | stem cell division(GO:0017145) |
| 0.0 | 1.1 | GO:0006275 | regulation of DNA replication(GO:0006275) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.4 | 10.3 | GO:0043259 | laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260) |
| 2.5 | 7.4 | GO:0044393 | microspike(GO:0044393) |
| 1.5 | 5.8 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 1.4 | 8.2 | GO:0002178 | palmitoyltransferase complex(GO:0002178) |
| 1.4 | 4.1 | GO:0035370 | UBC13-UEV1A complex(GO:0035370) |
| 1.2 | 6.1 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 1.2 | 6.1 | GO:0044094 | host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094) |
| 1.2 | 4.7 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
| 1.1 | 8.4 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 1.0 | 3.1 | GO:0032419 | extrinsic component of lysosome membrane(GO:0032419) |
| 0.9 | 17.3 | GO:0031254 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.9 | 11.9 | GO:0017146 | NMDA selective glutamate receptor complex(GO:0017146) |
| 0.8 | 4.1 | GO:0060201 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
| 0.8 | 2.3 | GO:0043511 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 0.8 | 8.5 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.8 | 8.3 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.7 | 4.0 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.7 | 13.7 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.6 | 5.2 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.6 | 4.5 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.6 | 2.4 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 0.5 | 21.6 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.5 | 6.4 | GO:0031464 | Cul4A-RING E3 ubiquitin ligase complex(GO:0031464) |
| 0.5 | 5.1 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.5 | 23.2 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.4 | 2.1 | GO:0035061 | interchromatin granule(GO:0035061) |
| 0.4 | 4.2 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.4 | 8.3 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.4 | 6.9 | GO:0044615 | nuclear pore central transport channel(GO:0044613) nuclear pore nuclear basket(GO:0044615) |
| 0.4 | 8.2 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453) |
| 0.4 | 1.8 | GO:0033503 | HULC complex(GO:0033503) |
| 0.4 | 6.8 | GO:0042599 | lamellar body(GO:0042599) |
| 0.3 | 12.1 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.3 | 3.1 | GO:0045180 | basal cortex(GO:0045180) |
| 0.3 | 2.0 | GO:0002177 | manchette(GO:0002177) |
| 0.3 | 6.4 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.3 | 1.3 | GO:0038039 | G-protein coupled receptor heterodimeric complex(GO:0038039) |
| 0.3 | 4.6 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.3 | 1.0 | GO:0035517 | PR-DUB complex(GO:0035517) |
| 0.3 | 1.3 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 0.3 | 7.9 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.3 | 2.1 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.3 | 11.0 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.3 | 2.9 | GO:0008278 | cohesin complex(GO:0008278) |
| 0.3 | 5.0 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.3 | 6.2 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.3 | 1.3 | GO:0001940 | male pronucleus(GO:0001940) |
| 0.3 | 5.8 | GO:0030904 | retromer complex(GO:0030904) |
| 0.3 | 3.3 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.2 | 0.7 | GO:0031228 | intrinsic component of Golgi membrane(GO:0031228) |
| 0.2 | 6.9 | GO:1990752 | microtubule end(GO:1990752) |
| 0.2 | 0.7 | GO:0097135 | X chromosome(GO:0000805) cyclin E2-CDK2 complex(GO:0097135) |
| 0.2 | 0.9 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.2 | 2.3 | GO:0070449 | elongin complex(GO:0070449) |
| 0.2 | 26.4 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.2 | 36.3 | GO:0043197 | dendritic spine(GO:0043197) |
| 0.2 | 2.4 | GO:0032059 | bleb(GO:0032059) |
| 0.2 | 1.0 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.2 | 1.5 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.1 | 1.5 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.1 | 0.7 | GO:0070847 | core mediator complex(GO:0070847) |
| 0.1 | 21.1 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.1 | 6.8 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.1 | 1.2 | GO:0031332 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.1 | 4.4 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
| 0.1 | 3.4 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.1 | 8.1 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.1 | 6.9 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.1 | 1.9 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.1 | 4.4 | GO:0032420 | stereocilium(GO:0032420) |
| 0.1 | 3.4 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.1 | 8.6 | GO:0005902 | microvillus(GO:0005902) |
| 0.1 | 1.1 | GO:0032039 | integrator complex(GO:0032039) |
| 0.1 | 0.6 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.1 | 0.7 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 0.1 | 7.5 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.1 | 1.4 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.1 | 4.8 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 0.1 | 8.3 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.1 | 2.4 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.1 | 7.6 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.1 | 8.6 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.1 | 3.5 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 24.4 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.1 | 8.9 | GO:0005903 | brush border(GO:0005903) |
| 0.1 | 3.8 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
| 0.1 | 9.4 | GO:0043204 | perikaryon(GO:0043204) |
| 0.1 | 3.8 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.1 | 1.5 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.1 | 2.0 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.1 | 6.9 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.1 | 0.7 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.1 | 0.6 | GO:0030132 | clathrin coat of coated pit(GO:0030132) |
| 0.1 | 9.0 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.1 | 3.6 | GO:0005776 | autophagosome(GO:0005776) |
| 0.1 | 30.4 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.1 | 0.9 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.1 | 1.7 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.0 | 0.7 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 4.6 | GO:0005814 | centriole(GO:0005814) |
| 0.0 | 1.0 | GO:0000780 | condensed nuclear chromosome, centromeric region(GO:0000780) |
| 0.0 | 6.1 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 0.5 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.0 | 1.6 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 7.5 | GO:0031252 | cell leading edge(GO:0031252) |
| 0.0 | 3.1 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.0 | 1.4 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.0 | 0.4 | GO:0005750 | mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275) |
| 0.0 | 0.2 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.0 | 7.4 | GO:0005819 | spindle(GO:0005819) |
| 0.0 | 0.8 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 1.4 | GO:0030496 | midbody(GO:0030496) |
| 0.0 | 1.5 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.0 | 1.7 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 9.4 | GO:0005774 | vacuolar membrane(GO:0005774) |
| 0.0 | 0.1 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.0 | 1.7 | GO:0005770 | late endosome(GO:0005770) |
| 0.0 | 1.4 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.0 | 1.1 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 0.0 | 3.6 | GO:0034774 | secretory granule lumen(GO:0034774) |
| 0.0 | 1.5 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.0 | 8.2 | GO:0019866 | mitochondrial inner membrane(GO:0005743) organelle inner membrane(GO:0019866) |
| 0.0 | 4.5 | GO:0098857 | membrane raft(GO:0045121) membrane microdomain(GO:0098857) |
| 0.0 | 0.3 | GO:0030867 | rough endoplasmic reticulum membrane(GO:0030867) |
| 0.0 | 2.5 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.0 | 1.8 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 0.6 | GO:0001669 | acrosomal vesicle(GO:0001669) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.4 | 7.2 | GO:0050613 | delta14-sterol reductase activity(GO:0050613) |
| 1.9 | 13.6 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 1.7 | 6.8 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 1.5 | 4.4 | GO:0034189 | very-low-density lipoprotein particle binding(GO:0034189) |
| 1.4 | 8.2 | GO:0034046 | poly(G) binding(GO:0034046) |
| 1.3 | 5.1 | GO:0004598 | peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598) |
| 1.2 | 15.0 | GO:0015194 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 1.2 | 3.7 | GO:0098808 | mRNA cap binding(GO:0098808) |
| 1.2 | 3.5 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
| 1.1 | 3.3 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
| 0.9 | 3.5 | GO:0004768 | stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215) |
| 0.8 | 6.8 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.8 | 4.2 | GO:0004883 | glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.8 | 5.0 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.8 | 4.1 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
| 0.8 | 5.6 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.7 | 2.2 | GO:0055100 | adiponectin binding(GO:0055100) |
| 0.7 | 2.9 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.7 | 2.9 | GO:0043273 | CTPase activity(GO:0043273) |
| 0.7 | 2.1 | GO:0016454 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.6 | 8.4 | GO:0043008 | ATP-dependent protein binding(GO:0043008) |
| 0.6 | 14.1 | GO:0004862 | cAMP-dependent protein kinase inhibitor activity(GO:0004862) |
| 0.6 | 3.7 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
| 0.6 | 4.2 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.6 | 4.7 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.6 | 2.9 | GO:0008532 | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532) |
| 0.5 | 1.6 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 0.5 | 1.6 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.5 | 3.1 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
| 0.5 | 40.9 | GO:0019003 | GDP binding(GO:0019003) |
| 0.4 | 3.1 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.4 | 12.5 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.4 | 9.0 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.4 | 1.7 | GO:0050119 | N-acetylglucosamine deacetylase activity(GO:0050119) |
| 0.4 | 3.0 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.4 | 1.7 | GO:0004924 | oncostatin-M receptor activity(GO:0004924) |
| 0.4 | 7.9 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.4 | 2.8 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 0.4 | 2.0 | GO:0016936 | galactoside binding(GO:0016936) |
| 0.4 | 9.2 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.4 | 1.2 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.4 | 8.1 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.4 | 1.1 | GO:0005010 | insulin-like growth factor-activated receptor activity(GO:0005010) |
| 0.4 | 1.5 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
| 0.4 | 2.2 | GO:0097100 | supercoiled DNA binding(GO:0097100) |
| 0.4 | 1.1 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 0.4 | 6.7 | GO:0019707 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.4 | 6.0 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.3 | 10.4 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.3 | 1.3 | GO:0004965 | G-protein coupled GABA receptor activity(GO:0004965) |
| 0.3 | 1.6 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.3 | 9.1 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
| 0.3 | 25.3 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.3 | 5.2 | GO:0042043 | neurexin family protein binding(GO:0042043) |
| 0.3 | 2.5 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 0.3 | 0.6 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 0.3 | 3.0 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 0.3 | 4.1 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.3 | 5.3 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.3 | 6.5 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.3 | 2.3 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.3 | 1.5 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
| 0.3 | 1.7 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
| 0.3 | 1.4 | GO:0016308 | 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308) |
| 0.3 | 5.3 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.3 | 4.1 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.2 | 2.2 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 0.2 | 2.1 | GO:0043426 | MRF binding(GO:0043426) |
| 0.2 | 1.1 | GO:0004839 | ubiquitin activating enzyme activity(GO:0004839) |
| 0.2 | 2.9 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.2 | 4.0 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.2 | 0.6 | GO:0004772 | sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736) |
| 0.2 | 2.9 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.2 | 1.6 | GO:0015349 | thyroid hormone transmembrane transporter activity(GO:0015349) |
| 0.2 | 3.7 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.2 | 0.8 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.2 | 8.6 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.2 | 2.9 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.2 | 1.3 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 0.2 | 11.2 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.2 | 2.1 | GO:0016413 | O-acetyltransferase activity(GO:0016413) |
| 0.2 | 7.5 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.2 | 5.4 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.2 | 10.9 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.2 | 11.2 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.2 | 6.7 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.2 | 1.1 | GO:0008079 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 0.2 | 1.7 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) |
| 0.2 | 3.0 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
| 0.1 | 4.4 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.1 | 2.0 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
| 0.1 | 5.3 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.1 | 26.4 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.1 | 1.0 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 0.1 | 1.0 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.1 | 1.5 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
| 0.1 | 2.3 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.1 | 1.3 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
| 0.1 | 0.5 | GO:0033677 | DNA/RNA helicase activity(GO:0033677) ATP-dependent 3'-5' DNA helicase activity(GO:0043140) |
| 0.1 | 1.0 | GO:0070878 | primary miRNA binding(GO:0070878) |
| 0.1 | 11.0 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.1 | 0.7 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 0.1 | 3.8 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.1 | 0.5 | GO:0052841 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848) |
| 0.1 | 5.7 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.1 | 0.7 | GO:0030267 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.1 | 2.3 | GO:0008483 | transaminase activity(GO:0008483) |
| 0.1 | 1.7 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.1 | 29.8 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.1 | 0.6 | GO:0043813 | phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) |
| 0.1 | 1.4 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.1 | 1.8 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
| 0.1 | 1.5 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.1 | 1.1 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.1 | 1.4 | GO:0005522 | profilin binding(GO:0005522) |
| 0.1 | 0.2 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.1 | 14.1 | GO:0008201 | heparin binding(GO:0008201) |
| 0.1 | 0.6 | GO:0008432 | JUN kinase binding(GO:0008432) |
| 0.1 | 0.3 | GO:0004698 | calcium-dependent protein kinase C activity(GO:0004698) |
| 0.1 | 17.8 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.1 | 1.7 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.1 | 1.5 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
| 0.1 | 1.4 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 8.8 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.1 | 1.3 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 0.1 | 2.7 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.1 | 1.9 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.1 | 24.5 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.1 | 0.1 | GO:0030375 | thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) |
| 0.1 | 3.0 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
| 0.1 | 0.3 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 0.1 | 1.2 | GO:0001671 | ATPase activator activity(GO:0001671) |
| 0.1 | 5.2 | GO:0015171 | amino acid transmembrane transporter activity(GO:0015171) |
| 0.1 | 4.7 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.1 | 0.7 | GO:0035173 | histone kinase activity(GO:0035173) |
| 0.1 | 0.8 | GO:0015280 | ligand-gated sodium channel activity(GO:0015280) |
| 0.0 | 1.4 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.0 | 4.1 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 3.8 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 2.4 | GO:0043621 | protein self-association(GO:0043621) |
| 0.0 | 3.3 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 3.0 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 0.3 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
| 0.0 | 3.8 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 0.9 | GO:0017048 | Rho GTPase binding(GO:0017048) |
| 0.0 | 0.2 | GO:0001733 | galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694) |
| 0.0 | 0.6 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.5 | GO:0015485 | cholesterol binding(GO:0015485) |
| 0.0 | 3.0 | GO:0017124 | SH3 domain binding(GO:0017124) |
| 0.0 | 2.5 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.0 | 1.3 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.0 | 0.8 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 0.7 | GO:0001105 | RNA polymerase II transcription coactivator activity(GO:0001105) |
| 0.0 | 1.3 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.0 | 8.0 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.0 | 0.1 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.0 | 1.7 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.0 | 0.4 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 3.0 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.5 | 10.3 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.5 | 28.7 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.5 | 30.4 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.4 | 10.5 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.4 | 22.7 | PID ATR PATHWAY | ATR signaling pathway |
| 0.3 | 12.4 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.3 | 13.5 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.2 | 10.3 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.2 | 3.8 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.2 | 7.2 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.2 | 13.6 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
| 0.2 | 11.4 | PID BMP PATHWAY | BMP receptor signaling |
| 0.2 | 7.9 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.2 | 5.2 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.1 | 5.1 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.1 | 10.0 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 15.8 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 4.1 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.1 | 2.8 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.1 | 4.4 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.1 | 2.5 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.1 | 1.1 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 7.0 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.1 | 0.3 | PID AVB3 INTEGRIN PATHWAY | Integrins in angiogenesis |
| 0.1 | 1.5 | PID FGF PATHWAY | FGF signaling pathway |
| 0.1 | 1.9 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.1 | 1.8 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.1 | 2.3 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.1 | 1.5 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.1 | 3.2 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.1 | 0.7 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.1 | 2.9 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.1 | 0.9 | PID ANGIOPOIETIN RECEPTOR PATHWAY | Angiopoietin receptor Tie2-mediated signaling |
| 0.0 | 1.3 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.0 | 0.6 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.0 | 2.3 | PID FOXO PATHWAY | FoxO family signaling |
| 0.0 | 1.8 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 3.3 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 0.9 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.0 | 2.4 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.0 | 1.5 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 0.4 | PID ERBB1 RECEPTOR PROXIMAL PATHWAY | EGF receptor (ErbB1) signaling pathway |
| 0.0 | 1.4 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.6 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.0 | 1.6 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.2 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.0 | 0.6 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.0 | 0.4 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.0 | 0.2 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.0 | 0.5 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.0 | 0.6 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 13.0 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.7 | 11.6 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.6 | 26.8 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.5 | 6.2 | REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 0.5 | 23.9 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.5 | 0.9 | REACTOME SOS MEDIATED SIGNALLING | Genes involved in SOS-mediated signalling |
| 0.5 | 11.4 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.5 | 14.9 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.4 | 11.3 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.4 | 8.7 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.4 | 9.9 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.3 | 8.0 | REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
| 0.3 | 11.0 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.3 | 8.8 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.3 | 7.1 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
| 0.3 | 3.8 | REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
| 0.3 | 3.3 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.2 | 11.7 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.2 | 4.8 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.2 | 2.2 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 0.2 | 8.1 | REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT | Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript |
| 0.2 | 2.3 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 0.2 | 7.2 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.2 | 3.9 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.2 | 5.2 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.2 | 1.3 | REACTOME SHC MEDIATED SIGNALLING | Genes involved in SHC-mediated signalling |
| 0.1 | 4.2 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.1 | 4.5 | REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 0.1 | 2.7 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.1 | 6.8 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 10.0 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.1 | 2.1 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.1 | 11.4 | REACTOME L1CAM INTERACTIONS | Genes involved in L1CAM interactions |
| 0.1 | 0.8 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.1 | 1.4 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.1 | 1.5 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 6.3 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.1 | 1.5 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.1 | 1.7 | REACTOME FGFR1 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR1 ligand binding and activation |
| 0.1 | 3.8 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.1 | 2.4 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.1 | 2.7 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.1 | 3.0 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.1 | 2.6 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 4.2 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.1 | 2.0 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.1 | 11.3 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 3.0 | REACTOME GLYCOSPHINGOLIPID METABOLISM | Genes involved in Glycosphingolipid metabolism |
| 0.1 | 1.5 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 1.6 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.1 | 1.5 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.1 | 0.9 | REACTOME HS GAG BIOSYNTHESIS | Genes involved in HS-GAG biosynthesis |
| 0.0 | 0.7 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.0 | 3.6 | REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 | Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0) |
| 0.0 | 5.5 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 0.9 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.0 | 1.0 | REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 | Genes involved in Regulation of AMPK activity via LKB1 |
| 0.0 | 1.4 | REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM | Genes involved in Transport of Mature Transcript to Cytoplasm |
| 0.0 | 2.3 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.0 | 0.7 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.0 | 3.1 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 0.3 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.0 | 0.8 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.0 | 4.8 | REACTOME TRANSLATION | Genes involved in Translation |
| 0.0 | 0.2 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.0 | 2.1 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 0.5 | REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 0.0 | 0.8 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 2.1 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 0.0 | 1.6 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 0.7 | REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS | Genes involved in Regulation of Water Balance by Renal Aquaporins |