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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for AAUGCCC

Z-value: 0.46

Motif logo

miRNA associated with seed AAUGCCC

NamemiRBASE accession
MIMAT0000710
MIMAT0022834

Activity profile of AAUGCCC motif

Sorted Z-values of AAUGCCC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AAUGCCC

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr18_-_61892997 5.54 ENST00000312828.4
ring finger protein 152
chr12_+_51424802 3.27 ENST00000453097.7
solute carrier family 4 member 8
chr11_-_103092145 3.21 ENST00000260247.10
ENST00000531543.1
defective in cullin neddylation 1 domain containing 5
chr21_-_26845402 2.45 ENST00000284984.8
ENST00000676955.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr3_+_114056728 1.59 ENST00000485050.5
ENST00000281273.8
ENST00000479882.5
ENST00000493014.1
queuine tRNA-ribosyltransferase accessory subunit 2
chr2_-_152717966 1.51 ENST00000410080.8
pre-mRNA processing factor 40 homolog A
chr12_+_72272360 1.37 ENST00000547300.2
ENST00000261180.10
thyrotropin releasing hormone degrading enzyme
chr12_-_15789375 1.35 ENST00000544064.1
ENST00000642939.1
ENST00000281172.10
ENST00000543523.5
ENST00000644374.1
ENST00000645775.1
ENST00000642278.1
ENST00000646123.1
ENST00000536793.5
epidermal growth factor receptor pathway substrate 8
chr3_-_55489938 1.35 ENST00000474267.5
Wnt family member 5A
chr9_-_14314067 1.09 ENST00000397575.7
nuclear factor I B
chr3_+_23945271 1.01 ENST00000312521.9
nuclear receptor subfamily 1 group D member 2
chr2_-_157874976 0.96 ENST00000682025.1
ENST00000683487.1
ENST00000682300.1
ENST00000683441.1
ENST00000684595.1
ENST00000683426.1
ENST00000683820.1
ENST00000263640.7
activin A receptor type 1
chr19_+_46347063 0.95 ENST00000012443.9
ENST00000391919.1
protein phosphatase 5 catalytic subunit
chr12_+_65824475 0.92 ENST00000403681.7
high mobility group AT-hook 2
chr3_+_172040554 0.92 ENST00000336824.8
ENST00000423424.5
fibronectin type III domain containing 3B
chr17_-_80035862 0.89 ENST00000310924.7
TBC1 domain family member 16
chr3_-_33440343 0.88 ENST00000283629.8
upstream binding protein 1
chr1_-_21783189 0.86 ENST00000400301.5
ENST00000532737.1
ubiquitin specific peptidase 48
chr19_-_49072699 0.84 ENST00000221444.2
potassium voltage-gated channel subfamily A member 7
chrX_-_110318062 0.82 ENST00000372059.6
ENST00000262844.10
AMMECR nuclear protein 1
chr12_-_31326111 0.81 ENST00000539409.5
SIN3-HDAC complex associated factor
chr3_-_113746218 0.80 ENST00000497255.1
ENST00000240922.8
ENST00000478020.1
ENST00000493900.5
N-alpha-acetyltransferase 50, NatE catalytic subunit
chr2_-_183038405 0.75 ENST00000361354.9
NCK associated protein 1
chr15_+_96330691 0.71 ENST00000394166.8
nuclear receptor subfamily 2 group F member 2
chr4_+_139015751 0.69 ENST00000280614.4
nocturnin
chrX_+_23334841 0.68 ENST00000379361.5
patched domain containing 1
chr2_+_46698909 0.68 ENST00000650611.1
ENST00000306503.5
long intergenic non-protein coding RNA 1118
suppressor of cytokine signaling 5
chr7_+_138460238 0.67 ENST00000343526.9
tripartite motif containing 24
chr10_-_118754956 0.66 ENST00000369151.8
CDK2 associated cullin domain 1
chr1_-_153615858 0.65 ENST00000476873.5
S100 calcium binding protein A14
chr21_+_36699100 0.65 ENST00000290399.11
SIM bHLH transcription factor 2
chr15_-_58749569 0.62 ENST00000402627.5
ENST00000559053.1
ENST00000260408.8
ENST00000561288.1
ENST00000461408.2
ENST00000439637.5
ENST00000558004.1
ADAM metallopeptidase domain 10
chr10_+_93993897 0.62 ENST00000371380.8
phospholipase C epsilon 1
chr8_-_56993803 0.61 ENST00000262644.9
3'(2'), 5'-bisphosphate nucleotidase 2
chr8_-_56211257 0.60 ENST00000316981.8
ENST00000423799.6
ENST00000429357.2
PLAG1 zinc finger
chr3_-_21751189 0.60 ENST00000281523.8
zinc finger protein 385D
chr12_+_67648737 0.58 ENST00000344096.4
ENST00000393555.3
dual specificity tyrosine phosphorylation regulated kinase 2
chr10_-_103855406 0.58 ENST00000355946.6
ENST00000369774.8
SH3 and PX domains 2A
chr3_-_79019444 0.57 ENST00000618833.4
ENST00000436010.6
ENST00000618846.4
roundabout guidance receptor 1
chr7_-_27165517 0.56 ENST00000396345.1
ENST00000343483.7
homeobox A9
chr1_-_155911340 0.56 ENST00000368323.8
Ras like without CAAX 1
chr6_-_134318097 0.55 ENST00000367858.10
ENST00000533224.1
serum/glucocorticoid regulated kinase 1
chr2_-_64653906 0.54 ENST00000313349.3
SERTA domain containing 2
chr18_-_63319987 0.53 ENST00000398117.1
BCL2 apoptosis regulator
chr6_-_111483190 0.52 ENST00000368802.8
REV3 like, DNA directed polymerase zeta catalytic subunit
chr11_+_34621065 0.52 ENST00000257831.8
ETS homologous factor
chr1_+_2228310 0.51 ENST00000378536.5
SKI proto-oncogene
chr12_-_75511594 0.51 ENST00000438169.6
ENST00000229214.9
KRR1 small subunit processome component homolog
chr15_+_51829644 0.51 ENST00000308580.12
tropomodulin 3
chr11_-_77820706 0.47 ENST00000440064.2
ENST00000528095.5
ENST00000308488.11
remodeling and spacing factor 1
chr9_+_111896804 0.47 ENST00000374279.4
UDP-glucose ceramide glucosyltransferase
chr3_-_47781837 0.47 ENST00000254480.10
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
chr1_-_37859583 0.46 ENST00000373036.5
metal regulatory transcription factor 1
chr2_-_207769889 0.46 ENST00000295417.4
frizzled class receptor 5
chr3_-_123884290 0.45 ENST00000346322.9
ENST00000360772.7
ENST00000360304.8
myosin light chain kinase
chr5_-_43313403 0.43 ENST00000325110.11
3-hydroxy-3-methylglutaryl-CoA synthase 1
chr11_-_27506751 0.42 ENST00000278193.7
ENST00000524596.1
lin-7 homolog C, crumbs cell polarity complex component
chr12_+_63844663 0.41 ENST00000355086.8
SLIT-ROBO Rho GTPase activating protein 1
chr17_-_28951285 0.41 ENST00000577226.5
PHD finger protein 12
chr12_+_2052977 0.40 ENST00000399634.6
ENST00000406454.8
ENST00000327702.12
ENST00000347598.9
ENST00000399603.6
ENST00000399641.6
ENST00000399655.6
ENST00000335762.10
ENST00000682835.1
calcium voltage-gated channel subunit alpha1 C
chr11_+_2444986 0.38 ENST00000155840.12
potassium voltage-gated channel subfamily Q member 1
chr3_-_48847797 0.37 ENST00000454963.5
ENST00000296446.12
ENST00000419216.1
ENST00000265563.13
protein kinase cAMP-dependent type II regulatory subunit alpha
chr5_+_112976757 0.35 ENST00000389063.3
decapping mRNA 2
chr12_+_50085325 0.35 ENST00000551966.5
ENST00000550477.5
ENST00000394963.9
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr8_-_38382146 0.35 ENST00000534155.1
ENST00000433384.6
ENST00000317025.13
ENST00000316985.7
nuclear receptor binding SET domain protein 3
chr5_+_75337211 0.35 ENST00000287936.9
ENST00000343975.9
3-hydroxy-3-methylglutaryl-CoA reductase
chr16_+_67029133 0.33 ENST00000290858.11
ENST00000412916.7
ENST00000564034.6
core-binding factor subunit beta
chr7_+_4682252 0.33 ENST00000328914.5
forkhead box K1
chr10_-_7787946 0.32 ENST00000379562.9
Kin17 DNA and RNA binding protein
chr16_+_53054973 0.31 ENST00000447540.6
ENST00000615216.4
ENST00000566029.5
chromodomain helicase DNA binding protein 9
chr5_+_134525649 0.30 ENST00000282605.8
ENST00000681547.2
ENST00000361895.6
ENST00000402835.5
jade family PHD finger 2
chr8_+_28494190 0.30 ENST00000537916.2
ENST00000240093.8
ENST00000523546.1
frizzled class receptor 3
chr1_-_205750167 0.30 ENST00000367142.5
nuclear casein kinase and cyclin dependent kinase substrate 1
chr1_-_155241220 0.29 ENST00000368373.8
ENST00000427500.7
glucosylceramidase beta
chr10_-_96586975 0.29 ENST00000371142.9
transmembrane 9 superfamily member 3
chrX_-_3713593 0.28 ENST00000262848.6
protein kinase X-linked
chr12_+_55743110 0.28 ENST00000257868.10
growth differentiation factor 11
chr20_+_58309704 0.28 ENST00000244040.4
RAB22A, member RAS oncogene family
chr10_+_87863595 0.28 ENST00000371953.8
phosphatase and tensin homolog
chr17_-_39401593 0.26 ENST00000394294.7
ENST00000264658.11
ENST00000583610.5
ENST00000647139.1
F-box and leucine rich repeat protein 20
chr10_-_118342292 0.26 ENST00000369172.8
ENST00000369183.9
family with sequence similarity 204 member A
chr8_+_53851786 0.25 ENST00000297313.8
ENST00000344277.10
regulator of G protein signaling 20
chr3_-_125375249 0.25 ENST00000484491.5
ENST00000492394.5
ENST00000471196.1
ENST00000468369.5
ENST00000485866.5
ENST00000360647.9
zinc finger protein 148
chr3_-_15859771 0.25 ENST00000399451.6
ankyrin repeat domain 28
chr4_-_73258785 0.24 ENST00000639793.1
ENST00000358602.9
ENST00000330838.10
ENST00000561029.1
ankyrin repeat domain 17
chr8_+_66667572 0.24 ENST00000520044.5
ENST00000519289.1
ENST00000521113.1
ENST00000661636.1
ENST00000521889.5
C8orf44-SGK3 readthrough
chromosome 8 open reading frame 44
chr20_-_13638903 0.24 ENST00000455532.5
ENST00000337743.9
taspase 1
chr16_-_79600698 0.24 ENST00000393350.1
MAF bZIP transcription factor
chr2_-_199457931 0.23 ENST00000417098.6
SATB homeobox 2
chr2_+_191678122 0.23 ENST00000425611.9
ENST00000410026.7
nucleic acid binding protein 1
chr10_-_96513911 0.22 ENST00000357947.4
tolloid like 2
chr3_-_48595267 0.22 ENST00000328333.12
ENST00000681320.1
collagen type VII alpha 1 chain
chr10_+_99659430 0.21 ENST00000370489.5
ectonucleoside triphosphate diphosphohydrolase 7
chr17_-_16215520 0.21 ENST00000582357.5
ENST00000436828.5
ENST00000268712.8
ENST00000411510.5
ENST00000395857.7
nuclear receptor corepressor 1
chr1_-_243850070 0.20 ENST00000366539.6
ENST00000672578.1
AKT serine/threonine kinase 3
chr7_-_84194781 0.20 ENST00000265362.9
semaphorin 3A
chr11_+_112025367 0.19 ENST00000679614.1
ENST00000679878.1
ENST00000280346.11
ENST00000681339.1
ENST00000681328.1
ENST00000681316.1
ENST00000531306.2
ENST00000680331.1
ENST00000393051.5
dihydrolipoamide S-acetyltransferase
chr7_-_13989658 0.18 ENST00000430479.6
ENST00000433547.1
ENST00000405192.6
ETS variant transcription factor 1
chr12_-_48788995 0.18 ENST00000550422.5
ENST00000357869.8
adenylate cyclase 6
chr7_+_139359846 0.17 ENST00000619796.4
ENST00000354926.9
LUC7 like 2, pre-mRNA splicing factor
chr1_+_63773966 0.17 ENST00000371079.6
ENST00000371080.5
receptor tyrosine kinase like orphan receptor 1
chr16_-_67806513 0.17 ENST00000317506.8
ENST00000448631.6
ENST00000602677.5
ENST00000630626.2
RAN binding protein 10
chr11_-_57515686 0.17 ENST00000533263.1
ENST00000278426.8
solute carrier family 43 member 1
chr12_+_4909895 0.16 ENST00000638821.1
ENST00000382545.5
novel transcript, sense overlapping KCNA1
potassium voltage-gated channel subfamily A member 1
chr3_+_14947568 0.16 ENST00000413118.5
ENST00000425241.5
nuclear receptor subfamily 2 group C member 2
chr15_+_68054308 0.15 ENST00000249636.11
protein inhibitor of activated STAT 1
chr12_-_66678934 0.15 ENST00000545666.5
ENST00000398016.7
ENST00000359742.9
ENST00000538211.5
glutamate receptor interacting protein 1
chr13_+_113584683 0.15 ENST00000375370.10
transcription factor Dp-1
chr7_-_151519891 0.14 ENST00000262187.10
Ras homolog, mTORC1 binding
chrX_-_84188148 0.14 ENST00000262752.5
ribosomal protein S6 kinase A6
chr14_-_36520222 0.14 ENST00000354822.7
NK2 homeobox 1
chr1_-_38873322 0.13 ENST00000397572.5
ENST00000494695.4
MYC binding protein
chr7_-_32891744 0.13 ENST00000304056.9
kelch repeat and BTB domain containing 2
chr12_-_89524734 0.13 ENST00000529983.3
polypeptide N-acetylgalactosaminyltransferase 4
chr11_-_31811314 0.12 ENST00000640368.2
ENST00000379123.10
ENST00000379115.9
ENST00000419022.6
ENST00000643871.1
ENST00000640610.1
ENST00000639034.2
paired box 6
chr1_+_78004930 0.12 ENST00000370763.6
DnaJ heat shock protein family (Hsp40) member B4
chr12_+_69470349 0.12 ENST00000547219.5
ENST00000550316.5
ENST00000548154.5
ENST00000547414.5
ENST00000549921.6
ENST00000550389.5
ENST00000550937.5
ENST00000549092.5
ENST00000550169.5
fibroblast growth factor receptor substrate 2
chr1_+_35931076 0.12 ENST00000397828.3
ENST00000373191.9
argonaute RISC catalytic component 3
chr5_+_149730260 0.11 ENST00000360453.8
ENST00000394320.7
ENST00000309241.10
PPARG coactivator 1 beta
chr17_-_58007217 0.10 ENST00000258962.5
ENST00000582730.6
ENST00000584773.5
ENST00000585096.1
serine and arginine rich splicing factor 1
chr14_+_55051639 0.10 ENST00000395468.9
ENST00000622254.1
mitogen-activated protein kinase 1 interacting protein 1 like
chrX_-_75156272 0.10 ENST00000620875.5
ENST00000669573.1
ENST00000339447.8
ENST00000645829.3
ENST00000529949.5
ENST00000373394.8
ENST00000253577.9
ENST00000644766.1
ENST00000534524.5
ATP binding cassette subfamily B member 7
chr16_+_70523782 0.09 ENST00000566095.6
ENST00000577085.1
ENST00000302516.10
ENST00000567654.1
splicing factor 3b subunit 3
chr11_+_47980538 0.08 ENST00000613246.4
ENST00000418331.7
ENST00000615445.4
ENST00000440289.6
protein tyrosine phosphatase receptor type J
chr9_-_125143457 0.08 ENST00000373549.8
ENST00000336505.11
suppressor of cancer cell invasion
chr1_-_28088564 0.08 ENST00000373863.3
ENST00000373871.8
ENST00000540618.5
ENST00000436342.6
EYA transcriptional coactivator and phosphatase 3
chr2_-_43226594 0.08 ENST00000282388.4
ZFP36 ring finger protein like 2
chr1_-_84997079 0.08 ENST00000284027.5
ENST00000370608.8
mucolipin TRP cation channel 2
chr2_+_131105326 0.08 ENST00000438882.6
ENST00000404460.5
pleckstrin homology domain containing B2
chr11_+_64306227 0.08 ENST00000405666.5
ENST00000468670.2
estrogen related receptor alpha
chr18_+_34493289 0.07 ENST00000682923.1
ENST00000596745.5
ENST00000283365.14
ENST00000315456.10
ENST00000598774.6
ENST00000684266.1
ENST00000683092.1
ENST00000683379.1
ENST00000684359.1
dystrobrevin alpha
chr1_+_161314372 0.06 ENST00000342751.8
ENST00000367975.7
ENST00000432287.6
ENST00000392169.6
ENST00000513009.5
succinate dehydrogenase complex subunit C
chr12_-_66130702 0.06 ENST00000446587.2
ENST00000266604.7
LLP homolog, long-term synaptic facilitation factor
chr1_+_28736927 0.06 ENST00000373812.8
ENST00000541996.5
ENST00000496288.5
YTH N6-methyladenosine RNA binding protein 2
chr12_+_56007484 0.06 ENST00000262032.9
IKAROS family zinc finger 4
chr3_+_152835122 0.06 ENST00000305097.6
purinergic receptor P2Y1
chr19_+_19320817 0.04 ENST00000262815.13
ENST00000609122.5
MAU2 sister chromatid cohesion factor
chrX_-_130110679 0.04 ENST00000335997.11
E74 like ETS transcription factor 4
chr9_-_23821275 0.04 ENST00000380110.8
ELAV like RNA binding protein 2
chr10_+_100745711 0.04 ENST00000370296.6
ENST00000428433.5
paired box 2
chr10_-_102114935 0.04 ENST00000361198.9
LIM domain binding 1
chr9_+_125261788 0.03 ENST00000461379.5
ENST00000297933.11
ENST00000394084.5
ENST00000394105.6
ENST00000470056.5
ENST00000394083.6
ENST00000495955.5
ENST00000467750.5
GTPase activating protein and VPS9 domains 1
chr12_+_27244222 0.03 ENST00000545470.5
ENST00000389032.8
ENST00000540996.5
serine/threonine kinase 38 like
chr4_-_148444674 0.03 ENST00000344721.8
nuclear receptor subfamily 3 group C member 2
chr11_+_63839086 0.03 ENST00000350490.11
ENST00000402010.8
microtubule affinity regulating kinase 2
chr5_-_65722094 0.02 ENST00000381007.9
small glutamine rich tetratricopeptide repeat containing beta
chr11_-_18634332 0.02 ENST00000336349.6
SPT2 chromatin protein domain containing 1
chr11_-_102843597 0.02 ENST00000299855.10
matrix metallopeptidase 3
chr1_+_3069160 0.01 ENST00000511072.5
PR/SET domain 16
chrX_+_74421450 0.01 ENST00000587091.6
solute carrier family 16 member 2
chr7_+_28412511 0.01 ENST00000357727.7
cAMP responsive element binding protein 5
chr16_+_50548387 0.01 ENST00000268459.6
NKD inhibitor of WNT signaling pathway 1
chr14_-_99272184 0.01 ENST00000357195.8
BAF chromatin remodeling complex subunit BCL11B
chr7_+_139341311 0.00 ENST00000297534.7
ENST00000541515.3
formation of mitochondrial complex V assembly factor 1 homolog
FMC1-LUC7L2 readthrough
chr8_+_127409026 0.00 ENST00000465342.4
POU class 5 homeobox 1B

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 5.5 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.4 1.3 GO:0060031 cardiac right atrium morphogenesis(GO:0003213) mediolateral intercalation(GO:0060031) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775) regulation of cell proliferation in midbrain(GO:1904933)
0.3 1.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.3 1.0 GO:0061445 endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445)
0.3 0.9 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.2 3.2 GO:0045116 protein neddylation(GO:0045116)
0.2 0.6 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.2 0.7 GO:0009956 radial pattern formation(GO:0009956)
0.2 0.5 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.2 0.6 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.1 0.3 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.1 0.6 GO:0050923 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.1 2.5 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.9 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.1 0.5 GO:0043375 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.5 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.1 0.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.1 1.0 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.5 GO:0060061 Spemann organizer formation(GO:0060061)
0.1 0.7 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.1 0.6 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.3 GO:0019046 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.1 1.1 GO:2000795 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 0.3 GO:1901805 beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.1 0.6 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.7 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.8 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.6 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 0.5 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.3 GO:1903984 rhythmic synaptic transmission(GO:0060024) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.8 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.1 0.6 GO:0042118 endothelial cell activation(GO:0042118)
0.1 3.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.2 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.0 0.2 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 0.2 GO:0021825 substrate-dependent cerebral cortex tangential migration(GO:0021825)
0.0 0.6 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.4 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.0 0.4 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.7 GO:0021794 thalamus development(GO:0021794)
0.0 1.0 GO:2000505 regulation of energy homeostasis(GO:2000505)
0.0 0.4 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.7 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.2 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 1.4 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.6 GO:0006400 tRNA modification(GO:0006400)
0.0 0.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.9 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.1 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 1.5 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.3 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0 0.1 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.2 GO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0 0.3 GO:0021511 spinal cord patterning(GO:0021511)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.3 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 0.0 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.0 0.3 GO:2000696 regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.2 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0048179 activin receptor complex(GO:0048179)
0.1 0.9 GO:1990635 proximal dendrite(GO:1990635)
0.1 0.7 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.8 GO:0031415 NatA complex(GO:0031415)
0.1 1.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 3.3 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 1.7 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 0.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.8 GO:0031209 SCAR complex(GO:0031209)
0.1 0.2 GO:0070876 SOSS complex(GO:0070876)
0.1 1.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.5 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.5 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.2 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.5 GO:0001741 XY body(GO:0001741)
0.0 1.8 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.4 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.5 GO:0046930 pore complex(GO:0046930)
0.0 2.7 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 5.2 GO:0031301 integral component of organelle membrane(GO:0031301)
0.0 0.0 GO:0032116 SMC loading complex(GO:0032116)
0.0 0.5 GO:0032040 small-subunit processome(GO:0032040)
0.0 4.3 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.1 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.6 GO:0002102 podosome(GO:0002102)
0.0 0.4 GO:0016514 SWI/SNF complex(GO:0016514) npBAF complex(GO:0071564)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 0.9 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.2 3.2 GO:0097602 cullin family protein binding(GO:0097602)
0.2 3.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 1.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.1 0.4 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.1 0.5 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.4 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.1 0.5 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.3 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717)
0.1 0.3 GO:0042282 hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
0.1 1.0 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.7 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.3 GO:0004348 glucosylceramidase activity(GO:0004348)
0.1 0.6 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 1.4 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.4 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 1.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.2 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.5 GO:0051434 BH3 domain binding(GO:0051434)
0.0 1.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936) coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 3.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 5.9 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.0 1.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.6 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.6 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.7 GO:0042379 chemokine receptor binding(GO:0042379)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.0 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 1.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.8 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.6 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.6 PID INSULIN PATHWAY Insulin Pathway
0.0 0.6 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.1 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 3.4 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.1 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 2.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.2 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion