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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for ACAGUAC
Z-value: 1.46
Motif logo
miRNA associated with seed ACAGUAC
| Name | miRBASE accession |
|---|---|
|
hsa-miR-101-3p.1
|
MIMAT0000099 |
Activity profile of ACAGUAC motif
Sorted Z-values of ACAGUAC motif
Network of associatons between targets according to the STRING database.
First level regulatory network of ACAGUAC
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.0 | 6.1 | GO:0045645 | regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) |
| 1.4 | 6.8 | GO:0044111 | development involved in symbiotic interaction(GO:0044111) |
| 1.2 | 5.0 | GO:1902544 | regulation of DNA N-glycosylase activity(GO:1902544) |
| 0.9 | 3.5 | GO:0031064 | negative regulation of histone deacetylation(GO:0031064) |
| 0.9 | 3.4 | GO:0007538 | primary sex determination(GO:0007538) |
| 0.8 | 6.6 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
| 0.8 | 3.3 | GO:1903976 | negative regulation of glial cell migration(GO:1903976) |
| 0.7 | 3.0 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
| 0.7 | 3.5 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.7 | 2.1 | GO:0046967 | cytosol to ER transport(GO:0046967) |
| 0.7 | 3.4 | GO:0040030 | regulation of molecular function, epigenetic(GO:0040030) |
| 0.6 | 14.3 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.6 | 1.8 | GO:0036333 | hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772) |
| 0.6 | 1.7 | GO:1990922 | regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922) |
| 0.6 | 2.3 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 0.5 | 8.1 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.5 | 1.6 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 0.5 | 6.7 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
| 0.5 | 2.4 | GO:0003408 | optic cup formation involved in camera-type eye development(GO:0003408) maintenance of chromatin silencing(GO:0006344) |
| 0.4 | 1.7 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
| 0.4 | 3.1 | GO:0071651 | positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651) |
| 0.4 | 1.4 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
| 0.4 | 1.4 | GO:1904116 | response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117) |
| 0.4 | 2.8 | GO:1904628 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
| 0.4 | 2.1 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
| 0.4 | 2.5 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.3 | 1.3 | GO:0097466 | protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382) |
| 0.3 | 1.3 | GO:0071409 | cellular response to cycloheximide(GO:0071409) |
| 0.3 | 1.0 | GO:1903691 | positive regulation of wound healing, spreading of epidermal cells(GO:1903691) |
| 0.3 | 1.6 | GO:0061428 | negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
| 0.3 | 0.9 | GO:0075732 | viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594) |
| 0.3 | 1.2 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.3 | 1.4 | GO:0070295 | renal water absorption(GO:0070295) positive regulation of hyaluronan biosynthetic process(GO:1900127) |
| 0.3 | 2.7 | GO:0035562 | negative regulation of chromatin binding(GO:0035562) |
| 0.3 | 1.9 | GO:0090270 | fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270) |
| 0.3 | 1.0 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
| 0.2 | 4.4 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.2 | 1.7 | GO:0007621 | negative regulation of female receptivity(GO:0007621) female courtship behavior(GO:0008050) |
| 0.2 | 0.7 | GO:0044752 | response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387) |
| 0.2 | 2.3 | GO:0072718 | response to cisplatin(GO:0072718) |
| 0.2 | 1.2 | GO:1902513 | regulation of organelle transport along microtubule(GO:1902513) |
| 0.2 | 1.6 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.2 | 2.7 | GO:0001675 | acrosome assembly(GO:0001675) |
| 0.2 | 0.7 | GO:0061085 | regulation of histone H3-K27 methylation(GO:0061085) |
| 0.2 | 1.1 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.2 | 2.2 | GO:0033327 | Leydig cell differentiation(GO:0033327) |
| 0.2 | 1.9 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.2 | 0.6 | GO:1901355 | response to rapamycin(GO:1901355) |
| 0.2 | 0.8 | GO:0034670 | chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550) |
| 0.2 | 0.8 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
| 0.2 | 0.6 | GO:0097535 | lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) |
| 0.2 | 0.6 | GO:0044830 | modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254) |
| 0.2 | 0.9 | GO:0072385 | minus-end-directed organelle transport along microtubule(GO:0072385) |
| 0.2 | 0.9 | GO:2000676 | positive regulation of type B pancreatic cell apoptotic process(GO:2000676) |
| 0.2 | 2.1 | GO:0001514 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.2 | 2.1 | GO:0070494 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
| 0.2 | 0.5 | GO:0015888 | thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934) |
| 0.2 | 2.5 | GO:0021694 | cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) |
| 0.2 | 2.1 | GO:0048096 | chromatin-mediated maintenance of transcription(GO:0048096) |
| 0.2 | 0.8 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 0.2 | 0.5 | GO:0045900 | negative regulation of translational elongation(GO:0045900) positive regulation of mRNA polyadenylation(GO:1900365) |
| 0.2 | 0.5 | GO:0071699 | olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) |
| 0.2 | 1.2 | GO:0070164 | negative regulation of adiponectin secretion(GO:0070164) |
| 0.1 | 3.4 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
| 0.1 | 0.7 | GO:0070433 | negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) |
| 0.1 | 0.9 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
| 0.1 | 1.3 | GO:0031087 | nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 0.1 | 2.3 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.1 | 1.4 | GO:0048386 | positive regulation of retinoic acid receptor signaling pathway(GO:0048386) |
| 0.1 | 6.5 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.1 | 2.4 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.1 | 1.6 | GO:0060628 | regulation of ER to Golgi vesicle-mediated transport(GO:0060628) |
| 0.1 | 2.4 | GO:0070208 | protein heterotrimerization(GO:0070208) |
| 0.1 | 0.7 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
| 0.1 | 0.7 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
| 0.1 | 0.5 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
| 0.1 | 1.9 | GO:0040033 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.1 | 0.1 | GO:1901187 | regulation of ephrin receptor signaling pathway(GO:1901187) |
| 0.1 | 1.0 | GO:0006265 | DNA topological change(GO:0006265) |
| 0.1 | 1.0 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
| 0.1 | 1.7 | GO:0051195 | negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198) |
| 0.1 | 1.0 | GO:0060754 | positive regulation of mast cell chemotaxis(GO:0060754) |
| 0.1 | 0.6 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 0.1 | 0.5 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 0.1 | 0.9 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 0.1 | 0.4 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) |
| 0.1 | 0.5 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 0.1 | 1.9 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.1 | 2.7 | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261) |
| 0.1 | 0.9 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.1 | 0.9 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 0.1 | 0.6 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.1 | 1.3 | GO:0010225 | response to UV-C(GO:0010225) protein neddylation(GO:0045116) |
| 0.1 | 0.3 | GO:0060849 | radial pattern formation(GO:0009956) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) |
| 0.1 | 2.4 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.1 | 0.2 | GO:1902617 | response to fluoride(GO:1902617) |
| 0.1 | 0.5 | GO:0090481 | pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) |
| 0.1 | 0.7 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.1 | 1.0 | GO:1902916 | positive regulation of protein polyubiquitination(GO:1902916) |
| 0.1 | 0.2 | GO:0061386 | closure of optic fissure(GO:0061386) |
| 0.1 | 1.0 | GO:0022417 | protein maturation by protein folding(GO:0022417) |
| 0.1 | 0.7 | GO:0048703 | embryonic viscerocranium morphogenesis(GO:0048703) |
| 0.1 | 0.2 | GO:0070634 | transepithelial ammonium transport(GO:0070634) |
| 0.1 | 0.3 | GO:0038165 | oncostatin-M-mediated signaling pathway(GO:0038165) leukemia inhibitory factor signaling pathway(GO:0048861) |
| 0.1 | 0.9 | GO:0050849 | negative regulation of calcium-mediated signaling(GO:0050849) |
| 0.1 | 2.9 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
| 0.1 | 2.5 | GO:2000272 | negative regulation of receptor activity(GO:2000272) |
| 0.1 | 5.7 | GO:0071349 | interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349) |
| 0.1 | 1.4 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 0.1 | 5.2 | GO:0032435 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435) |
| 0.1 | 0.2 | GO:0038026 | reelin-mediated signaling pathway(GO:0038026) |
| 0.1 | 0.6 | GO:2000645 | negative regulation of receptor catabolic process(GO:2000645) |
| 0.1 | 1.2 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.1 | 0.6 | GO:0031274 | positive regulation of pseudopodium assembly(GO:0031274) |
| 0.1 | 0.4 | GO:0070862 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
| 0.1 | 0.2 | GO:0072137 | condensed mesenchymal cell proliferation(GO:0072137) |
| 0.1 | 2.1 | GO:0032094 | response to food(GO:0032094) |
| 0.1 | 2.0 | GO:0015949 | nucleobase-containing small molecule interconversion(GO:0015949) |
| 0.1 | 0.5 | GO:1903142 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
| 0.0 | 3.2 | GO:0006893 | Golgi to plasma membrane transport(GO:0006893) |
| 0.0 | 2.9 | GO:0046513 | ceramide biosynthetic process(GO:0046513) |
| 0.0 | 0.2 | GO:0060665 | regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665) |
| 0.0 | 0.3 | GO:0001712 | ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712) |
| 0.0 | 0.4 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
| 0.0 | 1.3 | GO:0007020 | microtubule nucleation(GO:0007020) |
| 0.0 | 6.4 | GO:0045445 | myoblast differentiation(GO:0045445) |
| 0.0 | 1.3 | GO:0046475 | glycerophospholipid catabolic process(GO:0046475) |
| 0.0 | 0.4 | GO:0003344 | pericardium morphogenesis(GO:0003344) |
| 0.0 | 1.9 | GO:0006509 | membrane protein ectodomain proteolysis(GO:0006509) |
| 0.0 | 0.7 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.0 | 0.2 | GO:0070171 | negative regulation of tooth mineralization(GO:0070171) |
| 0.0 | 0.2 | GO:0006655 | phosphatidylglycerol biosynthetic process(GO:0006655) |
| 0.0 | 0.5 | GO:0007064 | mitotic sister chromatid cohesion(GO:0007064) |
| 0.0 | 0.1 | GO:1990167 | protein K27-linked deubiquitination(GO:1990167) |
| 0.0 | 0.6 | GO:0032793 | positive regulation of CREB transcription factor activity(GO:0032793) |
| 0.0 | 0.6 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 0.0 | 6.4 | GO:0016573 | histone acetylation(GO:0016573) |
| 0.0 | 1.0 | GO:0006301 | postreplication repair(GO:0006301) |
| 0.0 | 0.4 | GO:0039536 | negative regulation of RIG-I signaling pathway(GO:0039536) |
| 0.0 | 0.3 | GO:0060012 | synaptic transmission, glycinergic(GO:0060012) |
| 0.0 | 0.1 | GO:0061113 | pancreas morphogenesis(GO:0061113) |
| 0.0 | 1.0 | GO:0000281 | mitotic cytokinesis(GO:0000281) |
| 0.0 | 2.4 | GO:0031016 | pancreas development(GO:0031016) |
| 0.0 | 0.1 | GO:0001831 | trophectodermal cellular morphogenesis(GO:0001831) |
| 0.0 | 1.0 | GO:0070911 | global genome nucleotide-excision repair(GO:0070911) |
| 0.0 | 0.5 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.0 | 0.3 | GO:0070459 | prolactin secretion(GO:0070459) |
| 0.0 | 0.6 | GO:0015012 | heparan sulfate proteoglycan biosynthetic process(GO:0015012) |
| 0.0 | 2.3 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.0 | 1.2 | GO:0046627 | negative regulation of insulin receptor signaling pathway(GO:0046627) |
| 0.0 | 0.1 | GO:0042078 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 0.0 | 0.1 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 0.0 | 0.3 | GO:0000733 | DNA strand renaturation(GO:0000733) |
| 0.0 | 0.5 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.0 | 3.9 | GO:0051321 | meiotic cell cycle(GO:0051321) |
| 0.0 | 2.9 | GO:0001837 | epithelial to mesenchymal transition(GO:0001837) |
| 0.0 | 1.7 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.0 | 0.7 | GO:0060612 | adipose tissue development(GO:0060612) |
| 0.0 | 0.1 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.0 | 1.6 | GO:0031100 | organ regeneration(GO:0031100) |
| 0.0 | 1.0 | GO:0021762 | substantia nigra development(GO:0021762) |
| 0.0 | 0.1 | GO:0072383 | plus-end-directed vesicle transport along microtubule(GO:0072383) |
| 0.0 | 0.1 | GO:0050872 | white fat cell differentiation(GO:0050872) |
| 0.0 | 0.0 | GO:0032707 | negative regulation of interleukin-23 production(GO:0032707) |
| 0.0 | 0.8 | GO:0035987 | endodermal cell differentiation(GO:0035987) |
| 0.0 | 0.2 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.0 | 0.6 | GO:0099601 | regulation of neurotransmitter receptor activity(GO:0099601) |
| 0.0 | 0.2 | GO:0018026 | peptidyl-lysine monomethylation(GO:0018026) |
| 0.0 | 0.1 | GO:0071372 | cellular response to follicle-stimulating hormone stimulus(GO:0071372) |
| 0.0 | 0.1 | GO:0032455 | nerve growth factor processing(GO:0032455) |
| 0.0 | 0.5 | GO:0035666 | TRIF-dependent toll-like receptor signaling pathway(GO:0035666) |
| 0.0 | 0.9 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.0 | 0.0 | GO:1904017 | cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 0.0 | 1.6 | GO:0008033 | tRNA processing(GO:0008033) |
| 0.0 | 1.0 | GO:0007212 | dopamine receptor signaling pathway(GO:0007212) |
| 0.0 | 1.8 | GO:0046546 | male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546) |
| 0.0 | 1.4 | GO:0030183 | B cell differentiation(GO:0030183) |
| 0.0 | 0.1 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.0 | 0.1 | GO:1904059 | regulation of locomotor rhythm(GO:1904059) |
| 0.0 | 0.0 | GO:0010157 | response to chlorate(GO:0010157) |
| 0.0 | 0.2 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
| 0.0 | 1.3 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.0 | 0.1 | GO:0034616 | response to laminar fluid shear stress(GO:0034616) |
| 0.0 | 2.0 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.0 | 0.8 | GO:0051225 | spindle assembly(GO:0051225) |
| 0.0 | 0.6 | GO:0038034 | signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192) |
| 0.0 | 0.1 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 6.8 | GO:0044354 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 0.9 | 3.4 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
| 0.6 | 3.1 | GO:0033503 | HULC complex(GO:0033503) |
| 0.6 | 5.2 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.4 | 2.1 | GO:0042825 | TAP complex(GO:0042825) |
| 0.4 | 3.5 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.3 | 1.0 | GO:0035370 | UBC13-UEV1A complex(GO:0035370) |
| 0.3 | 1.1 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
| 0.2 | 1.9 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.2 | 0.7 | GO:0017109 | glutamate-cysteine ligase complex(GO:0017109) |
| 0.2 | 4.4 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.2 | 1.5 | GO:0016589 | NURF complex(GO:0016589) |
| 0.2 | 1.6 | GO:0030891 | VCB complex(GO:0030891) |
| 0.2 | 0.6 | GO:1902737 | dendritic filopodium(GO:1902737) |
| 0.2 | 1.0 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.2 | 0.8 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.1 | 1.5 | GO:0070937 | CRD-mediated mRNA stability complex(GO:0070937) |
| 0.1 | 2.4 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.1 | 4.5 | GO:0071564 | SWI/SNF complex(GO:0016514) npBAF complex(GO:0071564) |
| 0.1 | 10.0 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.1 | 1.8 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
| 0.1 | 1.0 | GO:0090544 | BAF-type complex(GO:0090544) |
| 0.1 | 1.0 | GO:0031298 | replication fork protection complex(GO:0031298) |
| 0.1 | 3.6 | GO:0035267 | NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562) |
| 0.1 | 1.4 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.1 | 0.7 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.1 | 13.2 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.1 | 7.9 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.1 | 1.4 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.1 | 3.9 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 1.4 | GO:0032059 | bleb(GO:0032059) |
| 0.1 | 1.4 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.1 | 1.4 | GO:0097470 | ribbon synapse(GO:0097470) |
| 0.1 | 1.6 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.1 | 1.6 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.1 | 2.9 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 0.8 | GO:0005638 | lamin filament(GO:0005638) |
| 0.1 | 0.7 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.1 | 1.2 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.1 | 1.2 | GO:0000145 | exocyst(GO:0000145) |
| 0.1 | 0.6 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.1 | 5.0 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.1 | 0.6 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 0.1 | 0.4 | GO:0005785 | signal recognition particle receptor complex(GO:0005785) |
| 0.1 | 0.9 | GO:0042575 | DNA polymerase complex(GO:0042575) |
| 0.1 | 5.7 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.1 | 6.8 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.1 | 1.2 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 11.1 | GO:0000775 | chromosome, centromeric region(GO:0000775) |
| 0.1 | 1.0 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.1 | 0.6 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.1 | 1.8 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.1 | 1.6 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.0 | 0.6 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.0 | 1.2 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 6.5 | GO:0034399 | nuclear periphery(GO:0034399) |
| 0.0 | 0.5 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.0 | 0.5 | GO:0000346 | transcription export complex(GO:0000346) |
| 0.0 | 1.9 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 4.2 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 1.2 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.4 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.0 | 1.6 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.7 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.0 | 0.4 | GO:1990909 | Wnt signalosome(GO:1990909) |
| 0.0 | 0.1 | GO:0031905 | early endosome lumen(GO:0031905) |
| 0.0 | 2.1 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 2.5 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 1.3 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.0 | 11.7 | GO:0005635 | nuclear envelope(GO:0005635) |
| 0.0 | 1.2 | GO:0030670 | phagocytic vesicle membrane(GO:0030670) |
| 0.0 | 4.4 | GO:0044798 | nuclear transcription factor complex(GO:0044798) |
| 0.0 | 0.6 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.0 | 0.5 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 1.1 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.0 | 0.2 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.0 | 2.3 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 1.8 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.0 | 2.2 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 1.4 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.0 | 1.1 | GO:0035580 | specific granule lumen(GO:0035580) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 6.4 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 1.7 | 5.0 | GO:0043739 | G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739) |
| 1.4 | 6.8 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 1.1 | 3.4 | GO:0043035 | chromatin insulator sequence binding(GO:0043035) |
| 1.0 | 3.1 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
| 0.9 | 3.4 | GO:0004748 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
| 0.8 | 5.8 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
| 0.8 | 3.3 | GO:0043273 | CTPase activity(GO:0043273) |
| 0.7 | 3.5 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 0.6 | 2.4 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
| 0.5 | 1.6 | GO:0005010 | insulin-like growth factor-activated receptor activity(GO:0005010) |
| 0.5 | 1.4 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
| 0.5 | 1.4 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.4 | 2.5 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.4 | 1.1 | GO:1990050 | phosphatidic acid transporter activity(GO:1990050) |
| 0.3 | 1.0 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 0.3 | 2.1 | GO:0046979 | peptide-transporting ATPase activity(GO:0015440) TAP2 binding(GO:0046979) |
| 0.3 | 1.3 | GO:0044378 | non-sequence-specific DNA binding, bending(GO:0044378) |
| 0.3 | 16.0 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.3 | 1.7 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.3 | 4.1 | GO:0016668 | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668) |
| 0.3 | 1.3 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.3 | 10.1 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.2 | 0.7 | GO:0004357 | glutamate-cysteine ligase activity(GO:0004357) |
| 0.2 | 3.5 | GO:0016884 | carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884) |
| 0.2 | 0.7 | GO:0001537 | N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) chondroitin 4-sulfotransferase activity(GO:0047756) |
| 0.2 | 1.6 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 0.2 | 0.6 | GO:0030158 | protein xylosyltransferase activity(GO:0030158) |
| 0.2 | 1.4 | GO:0016618 | hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267) |
| 0.2 | 2.2 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.2 | 6.1 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
| 0.2 | 6.0 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.2 | 1.8 | GO:0070878 | primary miRNA binding(GO:0070878) |
| 0.2 | 3.3 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.2 | 0.5 | GO:0015403 | thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) |
| 0.2 | 7.6 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.2 | 1.3 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.2 | 2.3 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.2 | 13.8 | GO:0019003 | GDP binding(GO:0019003) |
| 0.2 | 1.0 | GO:0051033 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.2 | 1.7 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.2 | 1.1 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 0.1 | 1.2 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
| 0.1 | 1.8 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.1 | 0.8 | GO:1990763 | arrestin family protein binding(GO:1990763) |
| 0.1 | 2.3 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 0.1 | 1.6 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.1 | 4.3 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.1 | 1.4 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.1 | 3.5 | GO:0016922 | ligand-dependent nuclear receptor binding(GO:0016922) |
| 0.1 | 2.2 | GO:0016832 | aldehyde-lyase activity(GO:0016832) |
| 0.1 | 0.3 | GO:0004450 | isocitrate dehydrogenase (NADP+) activity(GO:0004450) |
| 0.1 | 1.4 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.1 | 0.7 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
| 0.1 | 2.8 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.1 | 0.3 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) |
| 0.1 | 1.0 | GO:0016671 | oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671) |
| 0.1 | 1.1 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.1 | 1.4 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.1 | 0.6 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.1 | 1.5 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.1 | 1.3 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.1 | 0.4 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.1 | 0.1 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 0.1 | 2.5 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.1 | 0.2 | GO:0008511 | sodium:potassium:chloride symporter activity(GO:0008511) |
| 0.1 | 1.1 | GO:0034452 | dynactin binding(GO:0034452) |
| 0.1 | 0.5 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.1 | 0.8 | GO:0031386 | protein tag(GO:0031386) |
| 0.1 | 0.2 | GO:0034189 | very-low-density lipoprotein particle binding(GO:0034189) |
| 0.1 | 0.6 | GO:0035198 | miRNA binding(GO:0035198) |
| 0.1 | 2.7 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.1 | 0.6 | GO:0016286 | small conductance calcium-activated potassium channel activity(GO:0016286) |
| 0.1 | 3.4 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.1 | 0.8 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.1 | 0.3 | GO:0016934 | extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934) |
| 0.1 | 0.6 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.1 | 0.6 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 1.4 | GO:0048156 | tau protein binding(GO:0048156) |
| 0.1 | 1.1 | GO:0003756 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 0.0 | 1.5 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.0 | 2.3 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 0.0 | 0.5 | GO:0046625 | sphingolipid binding(GO:0046625) |
| 0.0 | 1.6 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.0 | 0.7 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
| 0.0 | 0.9 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 0.7 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 1.9 | GO:0008173 | RNA methyltransferase activity(GO:0008173) |
| 0.0 | 0.1 | GO:0047322 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405) |
| 0.0 | 1.5 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.0 | 0.9 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.0 | 0.9 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.1 | GO:0031208 | POZ domain binding(GO:0031208) |
| 0.0 | 0.9 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 1.0 | GO:0000980 | RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980) |
| 0.0 | 0.1 | GO:0005169 | neurotrophin TRKB receptor binding(GO:0005169) |
| 0.0 | 0.6 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.0 | 0.1 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.0 | 5.1 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.0 | 1.4 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.0 | 0.6 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.0 | 0.1 | GO:0050473 | arachidonate 15-lipoxygenase activity(GO:0050473) |
| 0.0 | 0.2 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.0 | 1.2 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 0.5 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.0 | 2.4 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.0 | 1.4 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.0 | 0.1 | GO:0016524 | latrotoxin receptor activity(GO:0016524) |
| 0.0 | 0.4 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.0 | 1.5 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.0 | 0.5 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 0.6 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 1.9 | GO:0004725 | protein tyrosine phosphatase activity(GO:0004725) |
| 0.0 | 1.2 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 1.0 | GO:0008375 | acetylglucosaminyltransferase activity(GO:0008375) |
| 0.0 | 0.2 | GO:0070567 | cytidylyltransferase activity(GO:0070567) |
| 0.0 | 2.1 | GO:0004386 | helicase activity(GO:0004386) |
| 0.0 | 0.6 | GO:0030145 | manganese ion binding(GO:0030145) |
| 0.0 | 0.5 | GO:0004198 | calcium-dependent cysteine-type endopeptidase activity(GO:0004198) |
| 0.0 | 0.4 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 0.1 | GO:0032041 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 0.0 | 1.0 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 0.1 | GO:0051434 | protein channel activity(GO:0015266) BH3 domain binding(GO:0051434) |
| 0.0 | 0.3 | GO:0001972 | retinoic acid binding(GO:0001972) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 1.2 | PID PI3KCI AKT PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.2 | 3.9 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.2 | 8.4 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.1 | 7.5 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.1 | 3.4 | PID S1P META PATHWAY | Sphingosine 1-phosphate (S1P) pathway |
| 0.1 | 1.4 | PID S1P S1P2 PATHWAY | S1P2 pathway |
| 0.1 | 1.7 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.1 | 1.9 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.1 | 10.3 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 1.6 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.1 | 2.7 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.1 | 2.4 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 1.7 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 2.8 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.0 | 0.1 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.0 | 4.2 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.0 | 1.5 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.0 | 6.7 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 1.2 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.0 | 0.9 | PID EPO PATHWAY | EPO signaling pathway |
| 0.0 | 1.4 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.0 | 1.3 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.0 | 3.4 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.8 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 0.7 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.0 | 0.7 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.0 | 2.5 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 1.0 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.0 | 1.0 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.0 | 1.2 | PID MET PATHWAY | Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) |
| 0.0 | 1.5 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.0 | 0.7 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.0 | 1.7 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.2 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.0 | 0.2 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.0 | 1.0 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 0.8 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.0 | 0.8 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 0.9 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.0 | 1.1 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 9.3 | REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
| 0.2 | 7.7 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.2 | 5.0 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.2 | 3.5 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.2 | 3.8 | REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
| 0.2 | 5.4 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.2 | 5.8 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.1 | 3.6 | REACTOME ADP SIGNALLING THROUGH P2RY12 | Genes involved in ADP signalling through P2Y purinoceptor 12 |
| 0.1 | 1.4 | REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
| 0.1 | 1.3 | REACTOME REGULATORY RNA PATHWAYS | Genes involved in Regulatory RNA pathways |
| 0.1 | 3.1 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.1 | 4.6 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 1.2 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.1 | 2.5 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.1 | 2.8 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.1 | 2.1 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.1 | 1.9 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 1.6 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.1 | 8.8 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.1 | 1.0 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.1 | 1.2 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.1 | 1.4 | REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX | Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex |
| 0.1 | 1.4 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.1 | 0.9 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.0 | 2.3 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.0 | 0.9 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.0 | 6.6 | REACTOME HOST INTERACTIONS OF HIV FACTORS | Genes involved in Host Interactions of HIV factors |
| 0.0 | 4.0 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.0 | 1.8 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 0.0 | 0.5 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.0 | 0.6 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.0 | 0.8 | REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB | Genes involved in PKA-mediated phosphorylation of CREB |
| 0.0 | 5.2 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 0.0 | 2.2 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 2.4 | REACTOME DNA REPAIR | Genes involved in DNA Repair |
| 0.0 | 0.7 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.0 | 0.8 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.0 | 0.8 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.0 | 0.3 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.0 | 0.1 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.0 | 0.4 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 0.5 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.0 | 0.2 | REACTOME IL 7 SIGNALING | Genes involved in Interleukin-7 signaling |
| 0.0 | 0.3 | REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER | Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer |
| 0.0 | 0.5 | REACTOME GROWTH HORMONE RECEPTOR SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.0 | 0.5 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.0 | 0.2 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.0 | 0.4 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.0 | 0.3 | REACTOME CITRIC ACID CYCLE TCA CYCLE | Genes involved in Citric acid cycle (TCA cycle) |
| 0.0 | 0.2 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |