Project
avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for ACAUUCA
Z-value: 0.57
Motif logo
miRNA associated with seed ACAUUCA
| Name | miRBASE accession |
|---|---|
|
hsa-miR-181a-5p
|
MIMAT0000256 |
|
hsa-miR-181b-5p
|
MIMAT0000257 |
|
hsa-miR-181c-5p
|
MIMAT0000258 |
|
hsa-miR-181d-5p
|
MIMAT0002821 |
|
hsa-miR-4262
|
MIMAT0016894 |
Activity profile of ACAUUCA motif
Sorted Z-values of ACAUUCA motif
Network of associatons between targets according to the STRING database.
First level regulatory network of ACAUUCA
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.2 | 6.7 | GO:2000374 | regulation of oxygen metabolic process(GO:2000374) |
| 1.5 | 10.3 | GO:0090170 | regulation of Golgi inheritance(GO:0090170) |
| 1.3 | 6.3 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 1.2 | 8.5 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 1.2 | 3.6 | GO:0060382 | release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382) |
| 1.2 | 3.5 | GO:0003245 | cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) |
| 1.1 | 3.4 | GO:0071072 | negative regulation of phospholipid biosynthetic process(GO:0071072) |
| 1.0 | 2.9 | GO:0021896 | forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897) |
| 1.0 | 6.8 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.9 | 3.6 | GO:0019470 | 4-hydroxyproline catabolic process(GO:0019470) |
| 0.9 | 2.7 | GO:0070837 | dehydroascorbic acid transport(GO:0070837) |
| 0.9 | 2.6 | GO:1904884 | signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884) |
| 0.9 | 4.3 | GO:0044821 | meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 0.8 | 3.3 | GO:0035948 | positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) |
| 0.8 | 7.9 | GO:0031547 | brain-derived neurotrophic factor receptor signaling pathway(GO:0031547) |
| 0.8 | 2.4 | GO:0034499 | late endosome to Golgi transport(GO:0034499) |
| 0.8 | 4.7 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.8 | 2.4 | GO:0006391 | transcription initiation from mitochondrial promoter(GO:0006391) |
| 0.8 | 3.1 | GO:0031064 | negative regulation of histone deacetylation(GO:0031064) |
| 0.8 | 4.6 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 0.8 | 3.0 | GO:0032072 | plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426) |
| 0.7 | 6.7 | GO:0032482 | Rab protein signal transduction(GO:0032482) |
| 0.7 | 2.9 | GO:0099558 | maintenance of synapse structure(GO:0099558) |
| 0.7 | 2.8 | GO:0072369 | regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369) |
| 0.7 | 3.5 | GO:0045906 | negative regulation of vasoconstriction(GO:0045906) |
| 0.7 | 5.5 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 0.7 | 4.8 | GO:0032328 | alanine transport(GO:0032328) |
| 0.7 | 2.1 | GO:0044830 | modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254) |
| 0.7 | 2.7 | GO:0023016 | signal transduction by trans-phosphorylation(GO:0023016) |
| 0.7 | 2.0 | GO:0090176 | microtubule cytoskeleton organization involved in establishment of planar polarity(GO:0090176) |
| 0.7 | 7.2 | GO:1902473 | regulation of protein localization to synapse(GO:1902473) |
| 0.7 | 2.6 | GO:0042663 | regulation of endodermal cell fate specification(GO:0042663) |
| 0.6 | 5.7 | GO:0031087 | deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 0.6 | 3.6 | GO:0033314 | mitotic DNA replication checkpoint(GO:0033314) |
| 0.6 | 4.1 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.6 | 1.2 | GO:0036216 | response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) |
| 0.6 | 3.4 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 0.6 | 5.7 | GO:0032510 | endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510) |
| 0.6 | 3.4 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
| 0.5 | 1.6 | GO:0006679 | glucosylceramide biosynthetic process(GO:0006679) |
| 0.5 | 4.3 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 0.5 | 2.6 | GO:0031291 | Ran protein signal transduction(GO:0031291) |
| 0.5 | 1.6 | GO:0070343 | white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) |
| 0.5 | 1.9 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.5 | 1.4 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of autophagosome maturation(GO:1901097) |
| 0.5 | 3.6 | GO:0071651 | positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651) |
| 0.4 | 4.0 | GO:0072386 | plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) |
| 0.4 | 5.8 | GO:1901223 | negative regulation of NIK/NF-kappaB signaling(GO:1901223) |
| 0.4 | 4.0 | GO:0006265 | DNA topological change(GO:0006265) |
| 0.4 | 6.6 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
| 0.4 | 2.8 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.4 | 7.2 | GO:0036010 | protein localization to endosome(GO:0036010) |
| 0.4 | 3.5 | GO:1900246 | positive regulation of RIG-I signaling pathway(GO:1900246) |
| 0.4 | 1.6 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
| 0.4 | 1.1 | GO:1904760 | myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760) negative regulation of vascular smooth muscle cell differentiation(GO:1905064) |
| 0.4 | 1.1 | GO:0006478 | peptidyl-tyrosine sulfation(GO:0006478) |
| 0.4 | 3.6 | GO:0071763 | nuclear membrane organization(GO:0071763) |
| 0.4 | 2.2 | GO:0010746 | regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) |
| 0.4 | 2.5 | GO:1902962 | regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963) |
| 0.4 | 0.7 | GO:0000912 | assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611) |
| 0.4 | 3.9 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
| 0.3 | 1.4 | GO:0018008 | N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201) |
| 0.3 | 2.4 | GO:0090292 | nuclear matrix anchoring at nuclear membrane(GO:0090292) |
| 0.3 | 2.7 | GO:1904627 | response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628) |
| 0.3 | 2.1 | GO:0061092 | regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092) |
| 0.3 | 1.0 | GO:2000863 | positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866) |
| 0.3 | 2.4 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.3 | 3.4 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.3 | 1.0 | GO:1900224 | positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) |
| 0.3 | 3.6 | GO:0061162 | establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339) |
| 0.3 | 2.0 | GO:0045876 | positive regulation of sister chromatid cohesion(GO:0045876) |
| 0.3 | 15.0 | GO:0035329 | hippo signaling(GO:0035329) |
| 0.3 | 1.9 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.3 | 2.2 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 0.3 | 1.9 | GO:1903679 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 0.3 | 2.1 | GO:0070560 | protein secretion by platelet(GO:0070560) |
| 0.3 | 3.8 | GO:0000338 | protein deneddylation(GO:0000338) |
| 0.3 | 1.4 | GO:0061687 | detoxification of inorganic compound(GO:0061687) |
| 0.3 | 3.7 | GO:0090168 | Golgi reassembly(GO:0090168) |
| 0.3 | 0.8 | GO:1904017 | cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 0.3 | 0.8 | GO:0034402 | recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402) |
| 0.3 | 3.2 | GO:0006610 | ribosomal protein import into nucleus(GO:0006610) |
| 0.3 | 0.8 | GO:0098935 | dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937) |
| 0.3 | 3.8 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.2 | 3.7 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.2 | 3.0 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 0.2 | 5.9 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 0.2 | 0.7 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
| 0.2 | 0.9 | GO:0060335 | positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335) |
| 0.2 | 4.5 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
| 0.2 | 0.7 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 0.2 | 2.0 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
| 0.2 | 0.7 | GO:0090038 | negative regulation of protein kinase C signaling(GO:0090038) |
| 0.2 | 0.7 | GO:0018160 | peptidyl-pyrromethane cofactor linkage(GO:0018160) |
| 0.2 | 9.4 | GO:0006376 | mRNA splice site selection(GO:0006376) |
| 0.2 | 1.7 | GO:0034316 | negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) |
| 0.2 | 2.1 | GO:0005981 | regulation of glycogen catabolic process(GO:0005981) |
| 0.2 | 1.7 | GO:0070862 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
| 0.2 | 4.3 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.2 | 2.7 | GO:2000394 | positive regulation of lamellipodium morphogenesis(GO:2000394) |
| 0.2 | 6.1 | GO:0000470 | maturation of LSU-rRNA(GO:0000470) |
| 0.2 | 1.2 | GO:0009212 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) |
| 0.2 | 2.4 | GO:0051574 | positive regulation of histone H3-K9 methylation(GO:0051574) |
| 0.2 | 1.4 | GO:0031339 | negative regulation of vesicle fusion(GO:0031339) |
| 0.2 | 0.6 | GO:1900161 | positive regulation of endodeoxyribonuclease activity(GO:0032079) regulation of phospholipid scramblase activity(GO:1900161) positive regulation of phospholipid scramblase activity(GO:1900163) regulation of glucosylceramide catabolic process(GO:2000752) positive regulation of glucosylceramide catabolic process(GO:2000753) regulation of sphingomyelin catabolic process(GO:2000754) positive regulation of sphingomyelin catabolic process(GO:2000755) |
| 0.2 | 3.8 | GO:0046033 | AMP metabolic process(GO:0046033) |
| 0.2 | 1.3 | GO:0001661 | conditioned taste aversion(GO:0001661) |
| 0.2 | 1.6 | GO:0080182 | histone H3-K4 trimethylation(GO:0080182) |
| 0.2 | 1.6 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 0.2 | 1.6 | GO:0043402 | glucocorticoid mediated signaling pathway(GO:0043402) |
| 0.2 | 1.4 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.2 | 0.7 | GO:0035360 | positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 0.2 | 9.6 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.2 | 2.0 | GO:0045292 | mRNA cis splicing, via spliceosome(GO:0045292) |
| 0.2 | 1.5 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 0.2 | 2.7 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.2 | 0.8 | GO:0061428 | negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
| 0.2 | 1.6 | GO:2001135 | regulation of endocytic recycling(GO:2001135) |
| 0.2 | 0.2 | GO:1901166 | neural crest cell migration involved in autonomic nervous system development(GO:1901166) |
| 0.1 | 0.6 | GO:1903371 | regulation of endoplasmic reticulum tubular network organization(GO:1903371) |
| 0.1 | 0.3 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
| 0.1 | 0.6 | GO:0071409 | cellular response to cycloheximide(GO:0071409) |
| 0.1 | 6.4 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.1 | 2.2 | GO:0070601 | centromeric sister chromatid cohesion(GO:0070601) |
| 0.1 | 1.0 | GO:1904424 | regulation of GTP binding(GO:1904424) |
| 0.1 | 0.8 | GO:0051708 | intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708) |
| 0.1 | 3.6 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.1 | 0.4 | GO:0071043 | CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) |
| 0.1 | 0.6 | GO:0002904 | positive regulation of B cell apoptotic process(GO:0002904) |
| 0.1 | 1.3 | GO:0060235 | lens induction in camera-type eye(GO:0060235) |
| 0.1 | 1.4 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 0.1 | 2.4 | GO:0071318 | cellular response to ATP(GO:0071318) |
| 0.1 | 0.5 | GO:1904550 | chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550) |
| 0.1 | 4.7 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.1 | 1.6 | GO:0015074 | DNA integration(GO:0015074) |
| 0.1 | 0.8 | GO:0015866 | ADP transport(GO:0015866) |
| 0.1 | 0.3 | GO:1904395 | positive regulation of receptor clustering(GO:1903911) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
| 0.1 | 2.0 | GO:0061157 | mRNA destabilization(GO:0061157) |
| 0.1 | 0.8 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.1 | 2.0 | GO:0032506 | cytokinetic process(GO:0032506) |
| 0.1 | 0.4 | GO:0061188 | regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188) |
| 0.1 | 0.7 | GO:0010044 | response to aluminum ion(GO:0010044) |
| 0.1 | 3.9 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.1 | 1.5 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.1 | 0.3 | GO:0048294 | negative regulation of isotype switching to IgE isotypes(GO:0048294) |
| 0.1 | 1.0 | GO:0006451 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.1 | 1.3 | GO:1904355 | positive regulation of telomere capping(GO:1904355) |
| 0.1 | 0.1 | GO:1902954 | regulation of early endosome to recycling endosome transport(GO:1902954) |
| 0.1 | 0.2 | GO:1905244 | regulation of modification of synaptic structure(GO:1905244) |
| 0.1 | 3.0 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.1 | 1.8 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
| 0.1 | 2.5 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 0.1 | 1.0 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.1 | 5.1 | GO:0046579 | positive regulation of Ras protein signal transduction(GO:0046579) |
| 0.1 | 0.9 | GO:1901725 | regulation of histone deacetylase activity(GO:1901725) positive regulation of histone deacetylase activity(GO:1901727) |
| 0.1 | 1.7 | GO:0070493 | thrombin receptor signaling pathway(GO:0070493) |
| 0.1 | 9.9 | GO:0030516 | regulation of axon extension(GO:0030516) |
| 0.1 | 2.7 | GO:2000401 | regulation of lymphocyte migration(GO:2000401) |
| 0.1 | 1.1 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 0.1 | 0.4 | GO:0035278 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.1 | 0.8 | GO:0060613 | fat pad development(GO:0060613) |
| 0.1 | 0.3 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
| 0.1 | 1.3 | GO:0090360 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 0.1 | 2.2 | GO:0043555 | regulation of translation in response to stress(GO:0043555) |
| 0.1 | 0.8 | GO:0039536 | negative regulation of RIG-I signaling pathway(GO:0039536) |
| 0.1 | 3.9 | GO:0050775 | positive regulation of dendrite morphogenesis(GO:0050775) |
| 0.1 | 0.4 | GO:0061010 | gall bladder development(GO:0061010) |
| 0.1 | 11.5 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.1 | 2.5 | GO:0048675 | axon extension(GO:0048675) |
| 0.1 | 1.4 | GO:0045723 | positive regulation of fatty acid biosynthetic process(GO:0045723) |
| 0.1 | 0.9 | GO:0090154 | positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304) |
| 0.1 | 1.2 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.1 | 3.5 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.1 | 0.3 | GO:0006272 | DNA replication, synthesis of RNA primer(GO:0006269) leading strand elongation(GO:0006272) |
| 0.1 | 7.8 | GO:0045445 | myoblast differentiation(GO:0045445) |
| 0.1 | 2.0 | GO:0003016 | respiratory system process(GO:0003016) |
| 0.1 | 1.2 | GO:1900745 | positive regulation of p38MAPK cascade(GO:1900745) |
| 0.1 | 0.5 | GO:0030578 | PML body organization(GO:0030578) |
| 0.1 | 0.4 | GO:2000576 | positive regulation of microtubule motor activity(GO:2000576) |
| 0.1 | 1.1 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
| 0.1 | 0.4 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.1 | 0.4 | GO:0006655 | phosphatidylglycerol biosynthetic process(GO:0006655) |
| 0.1 | 1.5 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.1 | 0.5 | GO:0006203 | dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061) |
| 0.1 | 7.6 | GO:0048813 | dendrite morphogenesis(GO:0048813) |
| 0.1 | 0.9 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.1 | 0.5 | GO:2001014 | regulation of skeletal muscle cell differentiation(GO:2001014) |
| 0.1 | 2.0 | GO:0034243 | regulation of transcription elongation from RNA polymerase II promoter(GO:0034243) |
| 0.1 | 0.1 | GO:0048633 | response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) positive regulation of skeletal muscle tissue growth(GO:0048633) |
| 0.1 | 1.2 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.1 | 0.9 | GO:0051642 | centrosome localization(GO:0051642) |
| 0.0 | 0.6 | GO:0042373 | vitamin K metabolic process(GO:0042373) |
| 0.0 | 5.3 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.0 | 0.0 | GO:0051589 | negative regulation of neurotransmitter secretion(GO:0046929) negative regulation of neurotransmitter transport(GO:0051589) |
| 0.0 | 0.9 | GO:0071218 | cellular response to misfolded protein(GO:0071218) |
| 0.0 | 0.4 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
| 0.0 | 0.9 | GO:0000715 | nucleotide-excision repair, DNA damage recognition(GO:0000715) |
| 0.0 | 1.1 | GO:0072662 | protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
| 0.0 | 0.1 | GO:0010520 | regulation of reciprocal meiotic recombination(GO:0010520) positive regulation of meiosis I(GO:0060903) |
| 0.0 | 0.2 | GO:0090481 | pyrimidine nucleotide-sugar transmembrane transport(GO:0090481) |
| 0.0 | 0.3 | GO:0033182 | regulation of histone ubiquitination(GO:0033182) |
| 0.0 | 0.5 | GO:0021694 | cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) |
| 0.0 | 0.2 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
| 0.0 | 0.5 | GO:0007289 | spermatid nucleus differentiation(GO:0007289) |
| 0.0 | 0.5 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
| 0.0 | 2.7 | GO:0006890 | retrograde vesicle-mediated transport, Golgi to ER(GO:0006890) |
| 0.0 | 1.5 | GO:0038128 | ERBB2 signaling pathway(GO:0038128) |
| 0.0 | 0.9 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
| 0.0 | 1.3 | GO:0046889 | positive regulation of lipid biosynthetic process(GO:0046889) |
| 0.0 | 0.1 | GO:2001023 | regulation of response to drug(GO:2001023) |
| 0.0 | 3.3 | GO:1901379 | regulation of potassium ion transmembrane transport(GO:1901379) |
| 0.0 | 3.9 | GO:0006805 | xenobiotic metabolic process(GO:0006805) |
| 0.0 | 0.1 | GO:0043985 | histone H4-R3 methylation(GO:0043985) |
| 0.0 | 0.1 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
| 0.0 | 0.6 | GO:1902166 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166) |
| 0.0 | 1.8 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.0 | 0.3 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.0 | 0.7 | GO:1990089 | response to nerve growth factor(GO:1990089) cellular response to nerve growth factor stimulus(GO:1990090) |
| 0.0 | 1.1 | GO:0001578 | microtubule bundle formation(GO:0001578) |
| 0.0 | 0.2 | GO:0044829 | positive regulation by host of viral genome replication(GO:0044829) |
| 0.0 | 0.8 | GO:0007223 | Wnt signaling pathway, calcium modulating pathway(GO:0007223) |
| 0.0 | 0.3 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.0 | 0.5 | GO:0051602 | response to electrical stimulus(GO:0051602) |
| 0.0 | 3.2 | GO:0044070 | regulation of anion transport(GO:0044070) |
| 0.0 | 1.4 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
| 0.0 | 0.6 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.0 | 1.4 | GO:0030183 | B cell differentiation(GO:0030183) |
| 0.0 | 0.1 | GO:0070977 | bone maturation(GO:0070977) |
| 0.0 | 0.8 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.0 | 0.6 | GO:0019985 | translesion synthesis(GO:0019985) |
| 0.0 | 0.4 | GO:1904659 | hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659) |
| 0.0 | 3.5 | GO:0009636 | response to toxic substance(GO:0009636) |
| 0.0 | 0.1 | GO:0019471 | 4-hydroxyproline metabolic process(GO:0019471) |
| 0.0 | 0.3 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.0 | 0.2 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.0 | 0.1 | GO:0006848 | pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475) |
| 0.0 | 0.2 | GO:0017145 | stem cell division(GO:0017145) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.9 | 8.6 | GO:0098843 | postsynaptic endocytic zone(GO:0098843) |
| 1.6 | 6.3 | GO:0070032 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) |
| 1.4 | 7.0 | GO:0043291 | RAVE complex(GO:0043291) |
| 1.3 | 4.0 | GO:0016939 | kinesin II complex(GO:0016939) |
| 1.3 | 5.1 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
| 1.3 | 6.3 | GO:0044308 | axonal spine(GO:0044308) |
| 1.0 | 6.1 | GO:0070545 | PeBoW complex(GO:0070545) |
| 0.9 | 4.3 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.8 | 4.2 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 0.8 | 2.3 | GO:0034657 | GID complex(GO:0034657) |
| 0.7 | 3.6 | GO:0005726 | perichromatin fibrils(GO:0005726) interchromatin granule(GO:0035061) |
| 0.7 | 2.1 | GO:1902737 | dendritic filopodium(GO:1902737) |
| 0.5 | 6.7 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.5 | 2.5 | GO:0070381 | endosome to plasma membrane transport vesicle(GO:0070381) |
| 0.5 | 1.5 | GO:0000805 | X chromosome(GO:0000805) |
| 0.5 | 2.9 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.4 | 8.3 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.4 | 1.7 | GO:0000798 | nuclear cohesin complex(GO:0000798) |
| 0.4 | 7.2 | GO:0000164 | protein phosphatase type 1 complex(GO:0000164) |
| 0.4 | 4.9 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 0.4 | 2.0 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
| 0.4 | 8.3 | GO:0044453 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453) |
| 0.4 | 5.1 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.3 | 2.4 | GO:0034992 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.3 | 3.1 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.3 | 4.1 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.3 | 2.2 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.3 | 2.5 | GO:0030891 | VCB complex(GO:0030891) |
| 0.3 | 2.2 | GO:0031415 | NatA complex(GO:0031415) |
| 0.3 | 3.7 | GO:0090543 | Flemming body(GO:0090543) |
| 0.3 | 2.0 | GO:0000235 | astral microtubule(GO:0000235) aster(GO:0005818) |
| 0.3 | 3.6 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 0.3 | 4.8 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.3 | 4.6 | GO:0032591 | dendritic spine membrane(GO:0032591) |
| 0.2 | 1.2 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.2 | 2.8 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.2 | 0.9 | GO:0071942 | XPC complex(GO:0071942) |
| 0.2 | 1.7 | GO:0035976 | AP1 complex(GO:0035976) |
| 0.2 | 2.1 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
| 0.2 | 0.8 | GO:0036502 | Derlin-1-VIMP complex(GO:0036502) |
| 0.2 | 3.2 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.2 | 1.0 | GO:0032444 | activin responsive factor complex(GO:0032444) |
| 0.2 | 6.8 | GO:0090545 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.2 | 4.9 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.2 | 3.0 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.2 | 3.3 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.2 | 12.8 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.2 | 2.4 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.1 | 0.4 | GO:0032116 | SMC loading complex(GO:0032116) |
| 0.1 | 1.2 | GO:0072487 | MSL complex(GO:0072487) |
| 0.1 | 1.2 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.1 | 3.2 | GO:0000780 | condensed nuclear chromosome, centromeric region(GO:0000780) |
| 0.1 | 2.3 | GO:0071141 | SMAD protein complex(GO:0071141) |
| 0.1 | 6.6 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
| 0.1 | 0.5 | GO:1990752 | microtubule end(GO:1990752) |
| 0.1 | 2.6 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.1 | 2.8 | GO:0031143 | pseudopodium(GO:0031143) |
| 0.1 | 0.3 | GO:0035370 | UBC13-UEV1A complex(GO:0035370) |
| 0.1 | 2.6 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.1 | 0.5 | GO:1990589 | ATF4-CREB1 transcription factor complex(GO:1990589) |
| 0.1 | 0.6 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.1 | 1.3 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.1 | 3.5 | GO:0032420 | stereocilium(GO:0032420) |
| 0.1 | 2.1 | GO:0031095 | spectrin-associated cytoskeleton(GO:0014731) platelet dense tubular network membrane(GO:0031095) |
| 0.1 | 7.7 | GO:0000777 | condensed chromosome kinetochore(GO:0000777) |
| 0.1 | 4.6 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.1 | 8.1 | GO:0031902 | late endosome membrane(GO:0031902) |
| 0.1 | 2.4 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.1 | 1.9 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.1 | 3.8 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.1 | 1.5 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.1 | 0.8 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.1 | 10.5 | GO:0000922 | spindle pole(GO:0000922) |
| 0.1 | 11.9 | GO:0048770 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.1 | 0.4 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.1 | 2.4 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.1 | 2.7 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 0.1 | 7.4 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.1 | 6.2 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.1 | 26.6 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.1 | 2.1 | GO:0031092 | platelet alpha granule membrane(GO:0031092) |
| 0.1 | 2.8 | GO:0002102 | podosome(GO:0002102) |
| 0.1 | 16.7 | GO:0014069 | postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572) |
| 0.1 | 0.5 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 1.7 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.0 | 1.5 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 2.4 | GO:0042645 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.0 | 0.6 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.0 | 0.3 | GO:0036157 | outer dynein arm(GO:0036157) |
| 0.0 | 5.7 | GO:0005770 | late endosome(GO:0005770) |
| 0.0 | 0.3 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.0 | 14.1 | GO:0031965 | nuclear membrane(GO:0031965) |
| 0.0 | 4.0 | GO:0030496 | midbody(GO:0030496) |
| 0.0 | 0.5 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.0 | 3.8 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.0 | 1.6 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.0 | 1.8 | GO:0036464 | cytoplasmic ribonucleoprotein granule(GO:0036464) |
| 0.0 | 9.2 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
| 0.0 | 1.7 | GO:0018995 | host(GO:0018995) host cell(GO:0043657) |
| 0.0 | 0.4 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.0 | 1.0 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 3.0 | GO:0005903 | brush border(GO:0005903) |
| 0.0 | 0.9 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.0 | 1.9 | GO:0043197 | dendritic spine(GO:0043197) |
| 0.0 | 1.0 | GO:0005930 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.0 | 1.4 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.0 | 6.5 | GO:0005874 | microtubule(GO:0005874) |
| 0.0 | 1.8 | GO:0030426 | growth cone(GO:0030426) |
| 0.0 | 0.1 | GO:0033503 | HULC complex(GO:0033503) |
| 0.0 | 1.1 | GO:0005819 | spindle(GO:0005819) |
| 0.0 | 0.3 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.0 | 0.2 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.0 | 4.3 | GO:0034702 | ion channel complex(GO:0034702) |
| 0.0 | 4.8 | GO:0010008 | endosome membrane(GO:0010008) |
| 0.0 | 0.5 | GO:0043034 | costamere(GO:0043034) |
| 0.0 | 0.1 | GO:0009331 | glycerol-3-phosphate dehydrogenase complex(GO:0009331) |
| 0.0 | 6.2 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 2.1 | GO:0005938 | cell cortex(GO:0005938) |
| 0.0 | 0.0 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.0 | 1.9 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
| 0.0 | 0.4 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.0 | 0.6 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.3 | 6.9 | GO:0004157 | dihydropyrimidinase activity(GO:0004157) |
| 2.3 | 6.9 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 1.3 | 3.9 | GO:0050613 | delta14-sterol reductase activity(GO:0050613) |
| 1.2 | 7.1 | GO:0034046 | poly(G) binding(GO:0034046) |
| 1.2 | 3.5 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
| 1.1 | 8.6 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 1.1 | 7.4 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 1.0 | 4.2 | GO:0043515 | kinetochore binding(GO:0043515) |
| 1.0 | 4.0 | GO:0044378 | non-sequence-specific DNA binding, bending(GO:0044378) |
| 1.0 | 2.9 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
| 0.9 | 3.6 | GO:0043273 | CTPase activity(GO:0043273) |
| 0.9 | 2.7 | GO:0033300 | dehydroascorbic acid transporter activity(GO:0033300) |
| 0.9 | 2.7 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
| 0.9 | 4.4 | GO:0005105 | type 1 fibroblast growth factor receptor binding(GO:0005105) |
| 0.8 | 3.8 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
| 0.7 | 2.9 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 0.7 | 3.4 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
| 0.6 | 3.1 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 0.6 | 3.6 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.6 | 2.4 | GO:0070363 | mitochondrial light strand promoter sense binding(GO:0070363) |
| 0.6 | 2.3 | GO:0035500 | MH2 domain binding(GO:0035500) |
| 0.6 | 5.2 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
| 0.6 | 6.7 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
| 0.6 | 5.5 | GO:0015385 | sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.6 | 3.3 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.5 | 2.6 | GO:0004677 | DNA-dependent protein kinase activity(GO:0004677) |
| 0.5 | 2.1 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
| 0.4 | 2.6 | GO:0038049 | transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) |
| 0.4 | 4.3 | GO:0015924 | mannosyl-oligosaccharide mannosidase activity(GO:0015924) |
| 0.4 | 3.4 | GO:0071933 | Arp2/3 complex binding(GO:0071933) |
| 0.4 | 3.0 | GO:0010858 | calcium-dependent protein kinase regulator activity(GO:0010858) |
| 0.4 | 8.5 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.4 | 1.9 | GO:0017018 | myosin phosphatase activity(GO:0017018) |
| 0.4 | 2.6 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
| 0.4 | 1.1 | GO:0008476 | protein-tyrosine sulfotransferase activity(GO:0008476) |
| 0.4 | 6.6 | GO:1990381 | ubiquitin-specific protease binding(GO:1990381) |
| 0.4 | 7.9 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.4 | 3.5 | GO:0046625 | sphingolipid binding(GO:0046625) |
| 0.3 | 1.4 | GO:0019107 | glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107) |
| 0.3 | 1.0 | GO:0080130 | L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130) |
| 0.3 | 1.4 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 0.3 | 10.0 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.3 | 7.1 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.3 | 3.8 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 0.2 | 3.4 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.2 | 6.8 | GO:0034236 | protein kinase A catalytic subunit binding(GO:0034236) |
| 0.2 | 1.0 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.2 | 0.9 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
| 0.2 | 0.7 | GO:0004418 | hydroxymethylbilane synthase activity(GO:0004418) |
| 0.2 | 2.8 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.2 | 3.8 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.2 | 2.1 | GO:0004445 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) |
| 0.2 | 1.2 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.2 | 2.0 | GO:0070883 | pre-miRNA binding(GO:0070883) |
| 0.2 | 0.6 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
| 0.2 | 0.2 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.2 | 2.5 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
| 0.2 | 7.9 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.2 | 0.7 | GO:0070404 | NADH binding(GO:0070404) |
| 0.2 | 4.9 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.2 | 6.3 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.2 | 4.3 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.2 | 1.6 | GO:0035251 | UDP-glucosyltransferase activity(GO:0035251) |
| 0.2 | 4.6 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.2 | 0.6 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.2 | 4.1 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.2 | 4.0 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.2 | 2.2 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.2 | 0.8 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
| 0.2 | 0.9 | GO:0002161 | aminoacyl-tRNA editing activity(GO:0002161) |
| 0.1 | 1.0 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.1 | 2.0 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.1 | 0.7 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 0.1 | 5.2 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.1 | 0.7 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 0.1 | 8.0 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.1 | 4.1 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.1 | 3.3 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.1 | 5.8 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.1 | 2.4 | GO:0038191 | neuropilin binding(GO:0038191) |
| 0.1 | 2.5 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.1 | 0.5 | GO:0032567 | dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793) guanyl deoxyribonucleotide binding(GO:0032560) dGTP binding(GO:0032567) |
| 0.1 | 4.3 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.1 | 1.6 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.1 | 0.8 | GO:0000295 | adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217) |
| 0.1 | 1.3 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.1 | 3.4 | GO:0070410 | co-SMAD binding(GO:0070410) |
| 0.1 | 2.7 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.1 | 2.0 | GO:0017070 | U6 snRNA binding(GO:0017070) |
| 0.1 | 7.0 | GO:0004004 | ATP-dependent RNA helicase activity(GO:0004004) |
| 0.1 | 3.6 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.1 | 1.4 | GO:0019855 | calcium channel inhibitor activity(GO:0019855) |
| 0.1 | 4.4 | GO:0032451 | demethylase activity(GO:0032451) |
| 0.1 | 1.3 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) |
| 0.1 | 2.3 | GO:0030275 | LRR domain binding(GO:0030275) |
| 0.1 | 1.2 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.1 | 3.2 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.1 | 0.6 | GO:0047057 | oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057) |
| 0.1 | 0.5 | GO:0008142 | oxysterol binding(GO:0008142) |
| 0.1 | 5.0 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.1 | 1.6 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
| 0.1 | 1.3 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.1 | 2.4 | GO:0005521 | lamin binding(GO:0005521) |
| 0.1 | 2.3 | GO:0008094 | DNA-dependent ATPase activity(GO:0008094) |
| 0.1 | 0.4 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.1 | 2.2 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.1 | 5.4 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.1 | 4.7 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.1 | 1.5 | GO:0004438 | phosphatidylinositol-3-phosphatase activity(GO:0004438) phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) phosphatidylinositol monophosphate phosphatase activity(GO:0052744) |
| 0.1 | 0.6 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
| 0.1 | 0.5 | GO:1990763 | arrestin family protein binding(GO:1990763) |
| 0.1 | 0.6 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.1 | 2.5 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 2.2 | GO:0043548 | phosphatidylinositol 3-kinase binding(GO:0043548) |
| 0.1 | 1.1 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 0.1 | 0.5 | GO:0043426 | MRF binding(GO:0043426) |
| 0.1 | 0.2 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
| 0.1 | 7.5 | GO:0002039 | p53 binding(GO:0002039) |
| 0.1 | 0.4 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.1 | 13.6 | GO:0044325 | ion channel binding(GO:0044325) |
| 0.1 | 0.7 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.1 | 3.0 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 0.1 | 0.5 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.1 | 1.0 | GO:0031996 | thioesterase binding(GO:0031996) |
| 0.1 | 2.7 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.1 | 1.4 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 0.1 | 1.1 | GO:0004177 | aminopeptidase activity(GO:0004177) |
| 0.1 | 3.1 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.1 | 4.1 | GO:0019003 | GDP binding(GO:0019003) |
| 0.1 | 0.4 | GO:0008312 | 7S RNA binding(GO:0008312) |
| 0.1 | 0.8 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.0 | 7.1 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.0 | 2.1 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.3 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.0 | 0.5 | GO:0044548 | S100 protein binding(GO:0044548) |
| 0.0 | 2.1 | GO:0019829 | cation-transporting ATPase activity(GO:0019829) |
| 0.0 | 4.8 | GO:0015171 | amino acid transmembrane transporter activity(GO:0015171) |
| 0.0 | 0.8 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 0.0 | 1.4 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.0 | 0.9 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 0.7 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 0.1 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
| 0.0 | 3.3 | GO:0004386 | helicase activity(GO:0004386) |
| 0.0 | 0.4 | GO:0031386 | protein tag(GO:0031386) |
| 0.0 | 1.1 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.0 | 0.4 | GO:0070567 | cytidylyltransferase activity(GO:0070567) |
| 0.0 | 4.5 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 0.6 | GO:0008409 | 5'-3' exonuclease activity(GO:0008409) |
| 0.0 | 6.8 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 0.4 | GO:0055056 | D-glucose transmembrane transporter activity(GO:0055056) |
| 0.0 | 3.1 | GO:0019888 | protein phosphatase regulator activity(GO:0019888) |
| 0.0 | 0.2 | GO:0015165 | pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165) |
| 0.0 | 7.1 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.0 | 0.1 | GO:0005477 | pyruvate secondary active transmembrane transporter activity(GO:0005477) |
| 0.0 | 1.1 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.0 | 1.8 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 0.3 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.0 | 0.5 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.0 | 0.1 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.0 | 1.4 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 1.8 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.0 | 0.6 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.0 | 0.3 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.0 | 0.1 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 0.0 | 0.3 | GO:0003756 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 0.0 | 0.2 | GO:0019966 | interleukin-1 binding(GO:0019966) |
| 0.0 | 0.1 | GO:0008503 | benzodiazepine receptor activity(GO:0008503) |
| 0.0 | 0.0 | GO:0044736 | acid-sensing ion channel activity(GO:0044736) |
| 0.0 | 0.5 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.0 | 0.1 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.0 | 0.3 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 3.3 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 0.1 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.0 | 0.5 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 15.2 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.3 | 12.5 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.3 | 3.6 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.2 | 9.8 | ST ERK1 ERK2 MAPK PATHWAY | ERK1/ERK2 MAPK Pathway |
| 0.2 | 5.2 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.2 | 8.5 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.2 | 9.4 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.2 | 5.7 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.1 | 3.7 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.1 | 4.5 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.1 | 8.0 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.1 | 6.2 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.1 | 2.7 | PID EPO PATHWAY | EPO signaling pathway |
| 0.1 | 2.5 | PID TCPTP PATHWAY | Signaling events mediated by TCPTP |
| 0.1 | 3.6 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.1 | 5.3 | PID INTEGRIN A4B1 PATHWAY | Alpha4 beta1 integrin signaling events |
| 0.1 | 1.8 | PID IGF1 PATHWAY | IGF1 pathway |
| 0.1 | 2.0 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.1 | 4.1 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.1 | 1.7 | SA G1 AND S PHASES | Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition. |
| 0.1 | 4.9 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.1 | 1.6 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.1 | 2.0 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.1 | 3.1 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.0 | 2.4 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 2.7 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 2.5 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.0 | 0.8 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.0 | 0.5 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.0 | 0.7 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 0.3 | PID PI3KCI AKT PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.0 | 0.7 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 1.5 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 1.2 | PID FOXO PATHWAY | FoxO family signaling |
| 0.0 | 1.6 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 0.8 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 0.8 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.0 | 1.4 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 2.3 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 0.6 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.0 | 0.3 | PID ATM PATHWAY | ATM pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 21.0 | REACTOME RAF MAP KINASE CASCADE | Genes involved in RAF/MAP kinase cascade |
| 0.7 | 1.4 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.7 | 9.9 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |
| 0.5 | 10.4 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.4 | 2.6 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.3 | 11.1 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.3 | 8.6 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.3 | 2.6 | REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY | Genes involved in Regulation of the Fanconi anemia pathway |
| 0.3 | 2.2 | REACTOME SOS MEDIATED SIGNALLING | Genes involved in SOS-mediated signalling |
| 0.3 | 9.0 | REACTOME RECYCLING PATHWAY OF L1 | Genes involved in Recycling pathway of L1 |
| 0.2 | 4.4 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.2 | 4.1 | REACTOME ACYL CHAIN REMODELLING OF PG | Genes involved in Acyl chain remodelling of PG |
| 0.2 | 5.4 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.2 | 5.7 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.2 | 11.1 | REACTOME MRNA 3 END PROCESSING | Genes involved in mRNA 3'-end processing |
| 0.2 | 7.8 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.2 | 7.4 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.2 | 5.6 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.2 | 2.4 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.2 | 2.9 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.1 | 0.6 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.1 | 2.7 | REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
| 0.1 | 2.3 | REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP | Genes involved in Destabilization of mRNA by Tristetraprolin (TTP) |
| 0.1 | 3.1 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.1 | 3.9 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.1 | 1.9 | REACTOME REGULATION OF IFNG SIGNALING | Genes involved in Regulation of IFNG signaling |
| 0.1 | 2.4 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 8.5 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 24.4 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.1 | 2.9 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.1 | 2.8 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.1 | 1.9 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 1.4 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.1 | 5.3 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.1 | 1.9 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 0.1 | 1.7 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 0.1 | 2.7 | REACTOME GABA A RECEPTOR ACTIVATION | Genes involved in GABA A receptor activation |
| 0.1 | 12.1 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 1.1 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 0.1 | 1.5 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.1 | 2.4 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.1 | 0.9 | REACTOME MITOCHONDRIAL TRNA AMINOACYLATION | Genes involved in Mitochondrial tRNA aminoacylation |
| 0.1 | 1.5 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.1 | 7.4 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.1 | 1.5 | REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
| 0.0 | 0.4 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.0 | 1.0 | REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION | Genes involved in Amino acid synthesis and interconversion (transamination) |
| 0.0 | 0.7 | REACTOME SYNTHESIS OF PA | Genes involved in Synthesis of PA |
| 0.0 | 0.3 | REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
| 0.0 | 0.2 | REACTOME SHC MEDIATED SIGNALLING | Genes involved in SHC-mediated signalling |
| 0.0 | 4.0 | REACTOME MRNA SPLICING | Genes involved in mRNA Splicing |
| 0.0 | 0.6 | REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS | Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements |
| 0.0 | 3.5 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 0.5 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 0.0 | 0.5 | REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES | Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases |
| 0.0 | 0.8 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 0.9 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.0 | 0.7 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.0 | 1.2 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.0 | 0.3 | REACTOME VITAMIN B5 PANTOTHENATE METABOLISM | Genes involved in Vitamin B5 (pantothenate) metabolism |
| 0.0 | 0.9 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 0.7 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.0 | 0.1 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.0 | 1.8 | REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION | Genes involved in Influenza Viral RNA Transcription and Replication |
| 0.0 | 0.4 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |