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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ACCCGUA

Z-value: 0.39

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miRNA associated with seed ACCCGUA

NamemiRBASE accession
hsa-miR-100-5p
MIMAT0000098
hsa-miR-99a-5p
MIMAT0000097
hsa-miR-99b-5p
MIMAT0000689

Activity profile of ACCCGUA motif

Sorted Z-values of ACCCGUA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ACCCGUA

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr3_+_152299392 0.44 ENST00000498502.5
ENST00000545754.5
ENST00000357472.7
ENST00000324196.9
MBNL1
muscleblind like splicing regulator 1
chr8_-_140635617 0.38 ENST00000220592.10
AGO2
argonaute RISC catalytic component 2
chr2_+_12716893 0.21 ENST00000381465.2
ENST00000155926.9
TRIB2
tribbles pseudokinase 2
chr8_+_125430333 0.19 ENST00000311922.4
TRIB1
tribbles pseudokinase 1
chr11_+_87037820 0.16 ENST00000340353.11
TMEM135
transmembrane protein 135
chr4_+_143513661 0.15 ENST00000283131.4
SMARCA5
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr6_-_75284736 0.14 ENST00000674038.1
ENST00000673730.1
ENST00000230461.11
TMEM30A
transmembrane protein 30A
chr6_-_89412219 0.10 ENST00000369415.9
RRAGD
Ras related GTP binding D
chr7_-_27095972 0.09 ENST00000355633.5
ENST00000643460.2
HOXA1
homeobox A1
chr22_+_29883158 0.08 ENST00000333027.7
ENST00000401950.7
ENST00000445401.5
ENST00000323630.9
ENST00000351488.7
MTMR3
myotubularin related protein 3
chr12_+_50085325 0.08 ENST00000551966.5
ENST00000550477.5
ENST00000394963.9
SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr2_+_28751802 0.07 ENST00000296122.10
ENST00000395366.3
PPP1CB
protein phosphatase 1 catalytic subunit beta
chr12_-_56636318 0.05 ENST00000549506.5
ENST00000379441.7
ENST00000551812.5
BAZ2A
bromodomain adjacent to zinc finger domain 2A
chr2_-_207769889 0.03 ENST00000295417.4
FZD5
frizzled class receptor 5
chr2_+_86720282 0.03 ENST00000283632.5
RMND5A
required for meiotic nuclear division 5 homolog A
chr8_+_74824526 0.02 ENST00000649643.1
ENST00000260113.7
PI15
peptidase inhibitor 15
chr1_+_244653081 0.02 ENST00000263831.11
ENST00000302550.16
DESI2
desumoylating isopeptidase 2
chr2_-_72147819 0.01 ENST00000001146.7
ENST00000546307.5
ENST00000474509.1
CYP26B1
cytochrome P450 family 26 subfamily B member 1
chr1_+_26234157 0.01 ENST00000640292.2
ENST00000451429.8
ENST00000252992.8
CEP85
centrosomal protein 85

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.1 0.4 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.2 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.1 GO:0071233 cellular response to leucine(GO:0071233)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.0 GO:0034657 GID complex(GO:0034657)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.4 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.4 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)