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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ACUGCAU

Z-value: 3.36

Motif logo

miRNA associated with seed ACUGCAU

NamemiRBASE accession
MIMAT0000274
MIMAT0027515

Activity profile of ACUGCAU motif

Sorted Z-values of ACUGCAU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ACUGCAU

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_-_108731505 8.89 ENST00000261401.8
ENST00000552871.5
coronin 1C
chr10_-_27154226 6.68 ENST00000427324.5
ENST00000375972.7
ENST00000326799.7
YME1 like 1 ATPase
chr9_+_110048598 6.60 ENST00000434623.6
ENST00000374525.5
PALM2 and AKAP2 fusion
chr2_+_234952009 5.96 ENST00000392011.7
SH3 domain binding protein 4
chr9_+_107283256 5.92 ENST00000358015.8
RAD23 homolog B, nucleotide excision repair protein
chr12_-_31326111 5.87 ENST00000539409.5
SIN3-HDAC complex associated factor
chr9_+_109780292 5.76 ENST00000374530.7
PALM2 and AKAP2 fusion
chr10_+_52314272 5.49 ENST00000373970.4
dickkopf WNT signaling pathway inhibitor 1
chr20_+_44885679 5.43 ENST00000353703.9
ENST00000372839.7
ENST00000428262.1
ENST00000445830.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
chr14_-_54489003 5.43 ENST00000554908.5
ENST00000616146.4
glia maturation factor beta
chr1_-_225653045 4.65 ENST00000366843.6
ENST00000366844.7
ENAH actin regulator
chr8_-_102864155 4.62 ENST00000682725.1
ENST00000337198.10
ENST00000681985.1
ENST00000684566.1
ENST00000683787.1
ENST00000682014.1
ENST00000682969.1
ENST00000684721.1
ENST00000347770.8
antizyme inhibitor 1
chr15_-_101252040 4.49 ENST00000254190.4
chondroitin sulfate synthase 1
chr4_-_68349981 4.37 ENST00000510746.1
ENST00000355665.7
ENST00000344157.9
YTH domain containing 1
chr15_+_56918612 4.27 ENST00000438423.6
ENST00000267811.9
ENST00000333725.10
ENST00000559609.5
transcription factor 12
chr1_-_70205531 3.97 ENST00000370952.4
leucine rich repeat containing 40
chr8_-_140635617 3.91 ENST00000220592.10
argonaute RISC catalytic component 2
chr10_-_96586975 3.81 ENST00000371142.9
transmembrane 9 superfamily member 3
chr2_+_99337364 3.64 ENST00000617677.1
ENST00000289371.11
eukaryotic translation initiation factor 5B
chr12_+_68610858 3.52 ENST00000393436.9
ENST00000425247.6
ENST00000250559.14
ENST00000489473.6
ENST00000422358.6
ENST00000541167.5
ENST00000538283.5
ENST00000341355.9
ENST00000537460.5
ENST00000450214.6
ENST00000545270.5
RAP1B, member of RAS oncogene family
chr17_-_62065248 3.42 ENST00000397786.7
mediator complex subunit 13
chr4_-_75673112 3.29 ENST00000395719.7
ENST00000677489.1
G3BP stress granule assembly factor 2
chr3_-_79019444 3.00 ENST00000618833.4
ENST00000436010.6
ENST00000618846.4
roundabout guidance receptor 1
chr14_+_61695777 2.99 ENST00000323441.10
hypoxia inducible factor 1 subunit alpha
chr5_-_133968578 2.88 ENST00000231512.5
chromosome 5 open reading frame 15
chr9_+_33025265 2.71 ENST00000330899.5
DnaJ heat shock protein family (Hsp40) member A1
chr19_+_41262480 2.68 ENST00000352456.7
ENST00000595018.5
ENST00000597725.5
heterogeneous nuclear ribonucleoprotein U like 1
chr5_+_112976757 2.60 ENST00000389063.3
decapping mRNA 2
chr6_+_110874775 2.57 ENST00000675380.1
ENST00000368882.8
ENST00000368877.9
ENST00000368885.8
ENST00000672937.2
adenosylmethionine decarboxylase 1
chr2_+_227472132 2.56 ENST00000409979.6
ENST00000310078.13
ArfGAP with FG repeats 1
chr3_-_160565560 2.51 ENST00000334256.9
ENST00000676866.1
ENST00000469804.1
karyopherin subunit alpha 4
chr14_+_100239121 2.45 ENST00000262238.10
YY1 transcription factor
chr12_-_92145838 2.39 ENST00000256015.5
BTG anti-proliferation factor 1
chr8_+_97644164 2.30 ENST00000336273.8
metadherin
chr9_-_72364504 2.28 ENST00000237937.7
ENST00000343431.6
ENST00000376956.3
zinc finger AN1-type containing 5
chr18_-_21111778 2.16 ENST00000399799.3
Rho associated coiled-coil containing protein kinase 1
chr12_+_103965863 2.15 ENST00000392872.8
ENST00000537100.5
thymine DNA glycosylase
chr5_-_138575359 2.12 ENST00000297185.9
ENST00000678300.1
ENST00000677425.1
ENST00000677064.1
ENST00000507115.6
heat shock protein family A (Hsp70) member 9
chr15_+_44537136 2.10 ENST00000261868.10
ENST00000535391.5
eukaryotic translation initiation factor 3 subunit J
chr2_+_28751802 2.06 ENST00000296122.10
ENST00000395366.3
protein phosphatase 1 catalytic subunit beta
chr12_+_67269328 2.04 ENST00000545606.6
cullin associated and neddylation dissociated 1
chr1_+_93079264 2.02 ENST00000370298.9
ENST00000370303.4
metal response element binding transcription factor 2
chr6_+_118894144 2.02 ENST00000229595.6
anti-silencing function 1A histone chaperone
chr10_-_5813387 1.91 ENST00000456041.5
ENST00000380181.7
ENST00000418688.5
ENST00000609712.1
ENST00000380191.9
GDP dissociation inhibitor 2
chr5_-_79512794 1.87 ENST00000282260.10
ENST00000508576.5
ENST00000535690.1
homer scaffold protein 1
chr7_-_26200734 1.82 ENST00000354667.8
ENST00000618183.5
heterogeneous nuclear ribonucleoprotein A2/B1
chr17_+_32350132 1.79 ENST00000321233.10
ENST00000394673.6
ENST00000394670.9
ENST00000579634.5
ENST00000580759.5
ENST00000342555.10
ENST00000577908.5
ENST00000394679.9
ENST00000582165.1
zinc finger protein 207
chr3_+_40309678 1.75 ENST00000232905.4
eukaryotic translation initiation factor 1B
chr10_+_87863595 1.71 ENST00000371953.8
phosphatase and tensin homolog
chr6_+_63572472 1.67 ENST00000370651.7
ENST00000626021.3
novel protein
protein tyrosine phosphatase 4A1
chr2_+_180980566 1.62 ENST00000410062.9
ubiquitin conjugating enzyme E2 E3
chr12_-_25250879 1.62 ENST00000256078.10
ENST00000311936.8
ENST00000556131.1
ENST00000557334.5
KRAS proto-oncogene, GTPase
chr3_+_33798557 1.57 ENST00000457054.6
ENST00000413073.1
ENST00000307296.8
programmed cell death 6 interacting protein
chr12_+_122752814 1.57 ENST00000455982.2
ENST00000280557.11
density regulated re-initiation and release factor
chr1_-_35193135 1.57 ENST00000357214.6
splicing factor proline and glutamine rich
chr2_+_108719473 1.56 ENST00000283195.11
RAN binding protein 2
chr6_+_20401864 1.55 ENST00000346618.8
ENST00000613242.4
E2F transcription factor 3
chrX_-_132218124 1.54 ENST00000342983.6
RAP2C, member of RAS oncogene family
chr1_-_244451896 1.52 ENST00000366535.4
adenylosuccinate synthase 2
chr4_+_76949743 1.51 ENST00000502584.5
ENST00000264893.11
ENST00000510641.5
septin 11
chr2_+_9206762 1.43 ENST00000315273.4
ENST00000281419.8
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chrX_-_134915232 1.42 ENST00000370783.8
motile sperm domain containing 1
chr17_+_62458641 1.38 ENST00000582809.5
tousled like kinase 2
chr11_-_86069043 1.36 ENST00000532317.5
ENST00000528256.1
ENST00000393346.8
ENST00000526033.5
phosphatidylinositol binding clathrin assembly protein
chr8_-_73972276 1.35 ENST00000518127.5
elongin C
chr2_+_168456215 1.31 ENST00000392687.4
ENST00000305747.11
ceramide synthase 6
chr5_-_128538230 1.30 ENST00000262464.9
fibrillin 2
chr15_+_41417104 1.28 ENST00000389629.8
RTF1 homolog, Paf1/RNA polymerase II complex component
chr5_+_151771884 1.26 ENST00000627077.2
ENST00000678976.1
ENST00000677408.1
ENST00000678070.1
ENST00000678964.1
ENST00000678925.1
ENST00000394123.7
ENST00000522761.6
ENST00000676827.1
G3BP stress granule assembly factor 1
chr17_-_18363504 1.23 ENST00000583780.1
ENST00000316694.8
ENST00000352886.10
serine hydroxymethyltransferase 1
chr16_+_81035830 1.21 ENST00000299575.5
ATM interactor
chr3_+_173398438 1.21 ENST00000457714.5
neuroligin 1
chr7_-_41703062 1.20 ENST00000242208.5
inhibin subunit beta A
chr8_+_103819244 1.19 ENST00000262231.14
ENST00000507740.5
ENST00000408894.6
regulating synaptic membrane exocytosis 2
chr20_+_63865228 1.17 ENST00000611972.4
ENST00000615907.4
ENST00000369927.8
ENST00000346249.9
ENST00000348257.9
ENST00000352482.8
ENST00000351424.8
ENST00000217121.9
ENST00000358548.4
TPD52 like 2
chr3_+_155870623 1.17 ENST00000295920.7
ENST00000496455.7
guanine monophosphate synthase
chr5_+_62306228 1.17 ENST00000381103.7
kinesin family member 2A
chr17_+_31936993 1.12 ENST00000322652.10
SUZ12 polycomb repressive complex 2 subunit
chr6_-_79234619 1.11 ENST00000344726.9
ENST00000275036.11
high mobility group nucleosomal binding domain 3
chr16_+_53703963 1.11 ENST00000636218.1
ENST00000637001.1
ENST00000471389.6
ENST00000637969.1
ENST00000640179.1
FTO alpha-ketoglutarate dependent dioxygenase
chr3_+_180912656 1.08 ENST00000357559.9
ENST00000491062.5
ENST00000468861.5
ENST00000445140.6
ENST00000484958.5
FMR1 autosomal homolog 1
chr1_+_26695993 1.06 ENST00000324856.13
ENST00000637465.1
AT-rich interaction domain 1A
chr10_-_86521737 1.04 ENST00000298767.10
WAPL cohesin release factor
chr9_-_15510991 1.00 ENST00000380715.5
ENST00000380716.8
ENST00000380738.8
PC4 and SFRS1 interacting protein 1
chr3_+_113747022 1.00 ENST00000273398.8
ENST00000496747.5
ENST00000475322.1
ATPase H+ transporting V1 subunit A
chr11_+_125592826 0.97 ENST00000529196.5
ENST00000392708.9
ENST00000649491.1
ENST00000531491.5
STT3 oligosaccharyltransferase complex catalytic subunit A
chr16_-_66751591 0.96 ENST00000440564.6
ENST00000443351.6
ENST00000566150.5
ENST00000258198.7
dynein cytoplasmic 1 light intermediate chain 2
chr19_-_47113756 0.93 ENST00000253048.10
zinc finger CCCH-type containing 4
chr15_-_41972504 0.89 ENST00000220325.9
EH domain containing 4
chr11_-_68213277 0.82 ENST00000401547.6
ENST00000304363.9
ENST00000453170.5
lysine methyltransferase 5B
chr10_-_119596495 0.80 ENST00000369093.6
TIA1 cytotoxic granule associated RNA binding protein like 1
chr16_+_12901591 0.75 ENST00000558583.3
shisa family member 9
chr6_-_53061740 0.71 ENST00000350082.10
ENST00000356971.3
ENST00000676107.1
ciliogenesis associated kinase 1
chr20_-_35742207 0.70 ENST00000397370.3
ENST00000528062.7
ENST00000374038.7
ENST00000253363.11
ENST00000361162.10
RNA binding motif protein 39
chr22_-_21867610 0.68 ENST00000215832.11
ENST00000398822.7
mitogen-activated protein kinase 1
chr2_+_177212724 0.63 ENST00000677043.1
ENST00000677863.1
ENST00000676681.1
ENST00000678111.1
ENST00000676874.1
ENST00000676736.1
ENST00000411529.6
ENST00000435711.5
heterogeneous nuclear ribonucleoprotein A3
chr1_+_24745396 0.62 ENST00000374379.9
chloride intracellular channel 4
chr7_+_103297425 0.59 ENST00000428154.5
ENST00000249269.9
peptidase, mitochondrial processing subunit beta
chr20_+_1118590 0.55 ENST00000246015.8
ENST00000335877.11
proteasome inhibitor subunit 1
chr16_+_15949549 0.51 ENST00000399408.7
ENST00000572882.3
ENST00000677164.1
ATP binding cassette subfamily C member 1
chr13_-_52848632 0.51 ENST00000377942.7
ENST00000338862.5
protocadherin 8
chr11_+_26332117 0.48 ENST00000531646.1
ENST00000256737.8
anoctamin 3
chr1_-_41918858 0.46 ENST00000372583.6
HIVEP zinc finger 3
chr12_+_104456962 0.43 ENST00000547956.1
ENST00000549260.5
carbohydrate sulfotransferase 11
chr13_+_32586443 0.43 ENST00000315596.15
PDS5 cohesin associated factor B
chr20_-_46363174 0.43 ENST00000372227.5
solute carrier family 35 member C2
chr4_+_56907876 0.41 ENST00000640168.2
ENST00000309042.12
RE1 silencing transcription factor
chr1_-_23980308 0.39 ENST00000374452.9
ENST00000492112.3
ENST00000343255.9
ENST00000344989.10
serine and arginine rich splicing factor 10
chr4_-_65670339 0.39 ENST00000273854.7
EPH receptor A5
chr7_-_84194781 0.28 ENST00000265362.9
semaphorin 3A
chr1_-_243850070 0.28 ENST00000366539.6
ENST00000672578.1
AKT serine/threonine kinase 3
chr8_-_30083053 0.25 ENST00000256255.11
ENST00000523761.1
store-operated calcium entry associated regulatory factor
chr3_+_30606574 0.24 ENST00000295754.10
ENST00000359013.4
transforming growth factor beta receptor 2
chr1_-_169485931 0.23 ENST00000367804.4
ENST00000646596.1
ENST00000236137.10
solute carrier family 19 member 2
chr5_-_168579319 0.23 ENST00000522176.1
ENST00000239231.7
pantothenate kinase 3
chr1_+_108692289 0.21 ENST00000370025.9
ENST00000370022.9
ENST00000370021.1
pre-mRNA processing factor 38B
chrX_+_12975083 0.21 ENST00000451311.7
ENST00000380636.1
thymosin beta 4 X-linked
chr10_+_110207587 0.15 ENST00000332674.9
ENST00000453116.5
MAX interactor 1, dimerization protein
chr10_+_43138435 0.12 ENST00000374466.4
chondroitin sulfate N-acetylgalactosaminyltransferase 2
chr12_+_62260338 0.12 ENST00000353364.7
ENST00000549523.5
ubiquitin specific peptidase 15
chr1_+_229271100 0.11 ENST00000366690.5
RAB4A, member RAS oncogene family
chr2_-_23927107 0.11 ENST00000238789.10
ATPase family AAA domain containing 2B
chr3_+_11272413 0.11 ENST00000446450.6
ENST00000354956.9
ENST00000354449.7
ENST00000419112.5
autophagy related 7
chr3_-_171460368 0.03 ENST00000436636.7
ENST00000465393.1
ENST00000341852.10
TRAF2 and NCK interacting kinase
chr15_-_82952683 0.02 ENST00000450735.7
ENST00000304231.12
homer scaffold protein 2
chr3_+_186783567 0.02 ENST00000323963.10
ENST00000440191.6
eukaryotic translation initiation factor 4A2
chr6_-_166382927 0.01 ENST00000360961.11
mitochondrial pyruvate carrier 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.5 GO:0009996 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) negative regulation of cell fate specification(GO:0009996)
1.5 4.6 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.8 6.7 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.7 3.0 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.7 8.9 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.7 5.4 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.7 3.3 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.7 3.9 GO:0090625 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.6 1.7 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.5 2.2 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.5 1.6 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.5 2.0 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.5 3.0 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.5 1.9 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.4 1.2 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.4 1.6 GO:0002188 translation reinitiation(GO:0002188)
0.4 2.6 GO:0008215 spermine metabolic process(GO:0008215) spermidine biosynthetic process(GO:0008295)
0.4 1.1 GO:0021897 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.3 1.0 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) regulation of chromosome condensation(GO:0060623) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.3 1.8 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.3 1.2 GO:0099543 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by soluble gas(GO:0099543)
0.3 2.7 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.3 2.6 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.3 1.6 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.3 1.6 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.2 2.1 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.2 1.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.2 5.1 GO:0032486 Rap protein signal transduction(GO:0032486)
0.2 2.0 GO:0010265 SCF complex assembly(GO:0010265)
0.2 0.7 GO:0019858 cytosine metabolic process(GO:0019858)
0.2 2.0 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 2.6 GO:0001675 acrosome assembly(GO:0001675)
0.2 1.1 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408)
0.2 3.5 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2 0.8 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.2 1.2 GO:0019264 L-serine catabolic process(GO:0006565) glycine biosynthetic process from serine(GO:0019264)
0.2 2.4 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.2 4.5 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)
0.2 1.6 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.2 1.4 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.2 1.3 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.2 1.2 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.2 0.5 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.2 0.5 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.2 2.5 GO:0010225 response to UV-C(GO:0010225)
0.2 5.9 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.1 2.1 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 1.3 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 0.4 GO:2000740 amniotic stem cell differentiation(GO:0097086) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798)
0.1 1.2 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1 5.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.1 1.4 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 5.4 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1 5.4 GO:0043090 amino acid import(GO:0043090)
0.1 2.6 GO:0019054 modulation by virus of host process(GO:0019054)
0.1 0.2 GO:0060434 bronchus morphogenesis(GO:0060434) lens fiber cell apoptotic process(GO:1990086)
0.1 0.2 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.1 0.3 GO:0048880 sensory system development(GO:0048880)
0.1 2.3 GO:0003016 respiratory system process(GO:0003016)
0.1 3.1 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.1 0.6 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.1 1.8 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.1 5.4 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 0.8 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.6 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 1.0 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.4 GO:0036066 pyrimidine nucleotide-sugar transport(GO:0015781) protein O-linked fucosylation(GO:0036066)
0.0 1.1 GO:0060148 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.9 GO:0006907 pinocytosis(GO:0006907)
0.0 3.9 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 1.6 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.4 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 2.3 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.0 0.3 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 1.1 GO:0016574 histone ubiquitination(GO:0016574)
0.0 1.0 GO:0051642 centrosome localization(GO:0051642)
0.0 1.3 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 1.3 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 1.0 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.8 GO:0017145 stem cell division(GO:0017145)
0.0 0.4 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.1 GO:0032482 Rab protein signal transduction(GO:0032482)
0.0 1.2 GO:0090307 mitotic spindle assembly(GO:0090307)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 1.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 2.1 GO:0006413 translational initiation(GO:0006413)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 5.9 GO:0071942 XPC complex(GO:0071942)
0.6 8.8 GO:0016600 flotillin complex(GO:0016600)
0.5 1.6 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.4 1.2 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.4 3.9 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.3 2.6 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.3 2.7 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.3 1.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.2 2.3 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 2.1 GO:0072357 glycogen granule(GO:0042587) PTW/PP1 phosphatase complex(GO:0072357)
0.2 1.6 GO:0042382 paraspeckles(GO:0042382)
0.1 2.2 GO:0032059 bleb(GO:0032059)
0.1 1.7 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 2.5 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 1.1 GO:0001739 sex chromatin(GO:0001739)
0.1 1.3 GO:0070449 elongin complex(GO:0070449)
0.1 1.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.6 GO:0090543 Flemming body(GO:0090543)
0.1 1.0 GO:0008278 cohesin complex(GO:0008278)
0.1 1.0 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 1.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 3.4 GO:0016592 mediator complex(GO:0016592)
0.1 1.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 2.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 1.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 5.4 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 5.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.6 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 5.1 GO:0005643 nuclear pore(GO:0005643)
0.0 2.5 GO:0043034 costamere(GO:0043034)
0.0 2.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 2.7 GO:0035577 azurophil granule membrane(GO:0035577)
0.0 1.1 GO:0071564 SWI/SNF complex(GO:0016514) npBAF complex(GO:0071564)
0.0 0.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 4.7 GO:0030175 filopodium(GO:0030175)
0.0 1.2 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.8 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.0 6.6 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 2.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.7 GO:0031143 pseudopodium(GO:0031143)
0.0 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0071011 precatalytic spliceosome(GO:0071011)
0.0 0.6 GO:0005839 proteasome core complex(GO:0005839)
0.0 2.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 6.7 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 1.7 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 1.4 GO:0005882 intermediate filament(GO:0005882)
0.0 0.6 GO:0005902 microvillus(GO:0005902)
0.0 2.1 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
1.3 3.9 GO:0098808 mRNA cap binding(GO:0098808)
1.0 6.7 GO:0050815 phosphoserine binding(GO:0050815)
0.9 2.6 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.8 6.7 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.7 2.2 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.7 5.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.7 4.6 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.6 1.7 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717)
0.5 6.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.5 5.5 GO:0039706 co-receptor binding(GO:0039706)
0.4 2.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.3 2.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.3 1.6 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.3 1.2 GO:0070905 serine binding(GO:0070905)
0.3 7.9 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 2.7 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.2 4.3 GO:0035497 cAMP response element binding(GO:0035497)
0.2 3.4 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 1.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 1.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.2 1.0 GO:0097100 supercoiled DNA binding(GO:0097100)
0.1 1.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.4 GO:0047756 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 9.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.6 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.5 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 2.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.9 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 1.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 1.0 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 5.9 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 4.7 GO:0050699 WW domain binding(GO:0050699)
0.1 1.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.1 7.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 3.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 2.5 GO:0000400 four-way junction DNA binding(GO:0000400)
0.1 6.8 GO:0019003 GDP binding(GO:0019003)
0.1 0.2 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 1.2 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.1 0.2 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 1.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 1.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 1.6 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 2.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 2.3 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 3.0 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 2.0 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.4 GO:0050733 RS domain binding(GO:0050733)
0.0 2.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 1.2 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.7 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 3.1 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 1.1 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 1.0 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 1.1 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 1.6 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 1.7 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.6 GO:0070628 proteasome binding(GO:0070628)
0.0 1.6 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 1.1 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.8 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 2.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.8 GO:0042393 histone binding(GO:0042393)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 2.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 5.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 8.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 3.0 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 2.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 1.7 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.1 1.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 3.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 3.2 PID PLK1 PATHWAY PLK1 signaling events
0.0 2.6 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 1.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 3.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.4 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.5 PID S1P S1P1 PATHWAY S1P1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 7.7 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.2 5.9 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.2 2.0 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 5.0 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.2 2.6 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.1 3.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 7.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 2.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.6 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 2.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.0 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 3.0 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 1.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 5.2 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 4.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 2.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 2.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.6 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 1.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.2 REACTOME KINESINS Genes involved in Kinesins
0.0 2.5 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 5.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 2.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 3.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 3.6 REACTOME TRANSLATION Genes involved in Translation
0.0 0.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.4 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 1.0 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 1.0 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation