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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for AGCACCA

Z-value: 5.04

Motif logo

miRNA associated with seed AGCACCA

NamemiRBASE accession
MIMAT0000086
MIMAT0000100
MIMAT0000681

Activity profile of AGCACCA motif

Sorted Z-values of AGCACCA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AGCACCA

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_+_94394886 45.69 ENST00000297268.11
ENST00000620463.1
collagen type I alpha 2 chain
chr2_+_188974364 37.33 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr1_-_204411804 32.44 ENST00000367188.5
protein phosphatase 1 regulatory subunit 15B
chr4_+_127965394 26.26 ENST00000645843.2
ENST00000388795.9
abhydrolase domain containing 18
chr16_+_55479188 25.43 ENST00000219070.9
matrix metallopeptidase 2
chr1_-_34859717 24.59 ENST00000423898.1
ENST00000521580.3
ENST00000456842.1
small integral membrane protein 12
chr16_-_46831134 24.33 ENST00000394806.6
ENST00000285697.9
chromosome 16 open reading frame 87
chr18_-_61892997 24.04 ENST00000312828.4
ring finger protein 152
chr17_-_50201618 23.66 ENST00000225964.10
collagen type I alpha 1 chain
chr3_-_120450981 23.55 ENST00000424703.6
ENST00000469005.1
ENST00000295633.8
follistatin like 1
chr1_+_151070740 21.86 ENST00000368918.8
GA binding protein transcription factor subunit beta 2
chr5_-_151686908 21.74 ENST00000231061.9
secreted protein acidic and cysteine rich
chr5_-_150155828 21.60 ENST00000261799.9
platelet derived growth factor receptor beta
chr1_+_24556087 19.37 ENST00000374392.3
non-compact myelin associated protein
chr2_-_237414157 17.74 ENST00000295550.9
ENST00000353578.9
ENST00000392004.7
ENST00000433762.1
ENST00000392003.6
collagen type VI alpha 3 chain
chr9_+_134641768 17.39 ENST00000371817.8
ENST00000618395.4
collagen type V alpha 1 chain
chr2_-_1744442 17.27 ENST00000433670.5
ENST00000425171.1
ENST00000252804.9
peroxidasin
chr11_-_103092145 16.17 ENST00000260247.10
ENST00000531543.1
defective in cullin neddylation 1 domain containing 5
chr13_+_110307276 15.18 ENST00000360467.7
ENST00000650540.1
collagen type IV alpha 2 chain
chr9_+_98943898 15.04 ENST00000375001.8
collagen type XV alpha 1 chain
chr3_-_57693045 14.78 ENST00000311128.10
DENN domain containing 6A
chr16_+_66880503 14.77 ENST00000568869.1
ENST00000311765.4
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr2_-_189179754 14.56 ENST00000374866.9
ENST00000618828.1
collagen type V alpha 2 chain
chr11_-_18634332 14.13 ENST00000336349.6
SPT2 chromatin protein domain containing 1
chr6_+_142147162 13.93 ENST00000452973.6
ENST00000620996.4
ENST00000367621.1
ENST00000367630.9
vesicle trafficking 1
chr14_-_44961889 13.58 ENST00000579157.1
ENST00000396128.9
ENST00000556500.1
kelch like family member 28
chr12_+_53938824 13.18 ENST00000243056.5
homeobox C13
chr8_+_42896883 13.00 ENST00000307602.9
hook microtubule tethering protein 3
chr15_-_48645701 12.88 ENST00000316623.10
ENST00000560355.1
fibrillin 1
chr8_-_33567118 12.41 ENST00000256257.2
ring finger protein 122
chr2_-_219245389 12.25 ENST00000428427.1
ENST00000432839.1
ENST00000295759.12
ENST00000424620.1
galactosidase beta 1 like
chr5_-_122078249 12.09 ENST00000231004.5
lysyl oxidase
chrX_-_51496572 12.05 ENST00000375992.4
nudix hydrolase 11
chr15_-_68432151 12.01 ENST00000423218.6
ENST00000315757.9
integrin subunit alpha 11
chr3_+_101724602 11.99 ENST00000341893.8
centrosomal protein 97
chr4_+_40056790 11.65 ENST00000261435.11
ENST00000515550.1
NEDD4 binding protein 2
chr5_-_79991237 11.62 ENST00000512560.5
ENST00000509852.6
ENST00000512528.3
ENST00000617335.4
metaxin 3
chr3_-_179451387 11.34 ENST00000675901.1
ENST00000232564.8
ENST00000674862.1
ENST00000497513.1
G protein subunit beta 4
chr18_+_46334007 11.16 ENST00000269439.12
ENST00000590330.1
ring finger protein 165
chr15_+_78438199 11.03 ENST00000258886.13
iron responsive element binding protein 2
chr8_-_65842051 10.58 ENST00000401827.8
phosphodiesterase 7A
chr17_-_1628808 10.42 ENST00000301335.10
solute carrier family 43 member 2
chr7_+_139231225 10.23 ENST00000473989.8
ubinuclein 2
chr3_-_195271147 10.22 ENST00000310380.11
xyloside xylosyltransferase 1
chr13_-_110307131 10.14 ENST00000543140.6
ENST00000375820.10
collagen type IV alpha 1 chain
chr1_+_236686454 10.08 ENST00000542672.6
ENST00000366578.6
ENST00000682015.1
ENST00000651275.1
actinin alpha 2
chr17_-_8152380 9.82 ENST00000317276.9
period circadian regulator 1
chr4_-_87220603 9.74 ENST00000273963.10
kelch like family member 8
chr2_+_73984902 9.70 ENST00000409262.8
tet methylcytosine dioxygenase 3
chr19_+_19320817 9.62 ENST00000262815.13
ENST00000609122.5
MAU2 sister chromatid cohesion factor
chr10_-_29735787 9.46 ENST00000375400.7
supervillin
chr6_+_36442985 9.40 ENST00000373731.7
ENST00000483557.5
ENST00000498267.5
ENST00000449081.6
ENST00000460983.1
potassium channel tetramerization domain containing 20
chr17_-_42423246 9.23 ENST00000357037.6
caveolae associated protein 1
chr17_-_28614174 9.12 ENST00000530121.5
ENST00000301037.11
ENST00000531839.5
ribosomal protein S6 kinase related
novel protein
chr2_+_69915100 9.11 ENST00000264444.7
MAX dimerization protein 1
chr22_+_39994926 9.02 ENST00000333407.11
family with sequence similarity 83 member F
chr11_-_86955385 9.00 ENST00000531380.2
frizzled class receptor 4
chr14_+_73644875 8.98 ENST00000554113.5
ENST00000553645.7
ENST00000555631.6
ENST00000311089.7
ENST00000555919.7
ENST00000554339.5
ENST00000554871.5
dynein axonemal light chain 1
chr11_+_75562056 8.88 ENST00000533603.5
serpin family H member 1
chr2_+_26848093 8.71 ENST00000288699.11
dihydropyrimidinase like 5
chr1_+_19664859 8.63 ENST00000289753.2
5-hydroxytryptamine receptor 6
chr8_+_11284789 8.61 ENST00000221086.8
myotubularin related protein 9
chrX_-_50814095 8.59 ENST00000376020.8
shroom family member 4
chr10_-_118754956 8.55 ENST00000369151.8
CDK2 associated cullin domain 1
chr3_-_149752443 8.50 ENST00000473414.6
COMM domain containing 2
chr6_+_28349907 8.37 ENST00000252211.7
ENST00000341464.9
ENST00000377255.3
zinc finger with KRAB and SCAN domains 3
chr11_-_59615673 8.34 ENST00000263847.6
oxysterol binding protein
chr9_-_107489754 8.27 ENST00000610832.1
ENST00000374672.5
Kruppel like factor 4
chr1_-_114780624 8.24 ENST00000060969.6
ENST00000369528.9
suppressor of IKBKE 1
chr15_+_50908674 8.22 ENST00000261842.10
ENST00000560508.1
adaptor related protein complex 4 subunit epsilon 1
chr1_-_112956063 8.14 ENST00000538576.5
ENST00000369626.8
ENST00000458229.6
solute carrier family 16 member 1
chr4_+_123399488 7.96 ENST00000394339.2
sprouty RTK signaling antagonist 1
chr1_-_236065079 7.93 ENST00000264187.7
ENST00000366595.7
nidogen 1
chr3_-_48595267 7.63 ENST00000328333.12
ENST00000681320.1
collagen type VII alpha 1 chain
chr3_-_120349294 7.59 ENST00000295628.4
leucine rich repeat containing 58
chr13_+_42048645 7.58 ENST00000337343.9
ENST00000261491.9
ENST00000611224.1
diacylglycerol kinase eta
chr1_+_203475798 7.53 ENST00000343110.3
proline and arginine rich end leucine rich repeat protein
chr19_-_10010492 7.51 ENST00000264828.4
collagen type V alpha 3 chain
chr3_+_190514051 7.50 ENST00000072516.7
ENST00000439062.6
interleukin 1 receptor accessory protein
chr1_-_31704001 7.49 ENST00000373672.8
collagen type XVI alpha 1 chain
chr15_+_99251362 7.42 ENST00000558879.5
ENST00000301981.8
ENST00000447360.6
ENST00000558172.5
ENST00000561276.5
ENST00000331450.9
leucine rich repeat containing 28
chr17_+_47733228 7.42 ENST00000177694.2
T-box transcription factor 21
chrX_+_151176582 7.38 ENST00000218316.4
G protein-coupled receptor 50
chr5_+_157743703 7.36 ENST00000286307.6
LSM11, U7 small nuclear RNA associated
chr19_+_46297032 7.35 ENST00000377670.9
hypoxia inducible factor 3 subunit alpha
chrX_-_53225176 7.34 ENST00000404049.7
ENST00000375401.8
lysine demethylase 5C
chr7_+_74028127 7.33 ENST00000438880.5
ENST00000414324.5
ENST00000380562.8
ENST00000380575.8
ENST00000380584.8
ENST00000458204.5
ENST00000357036.9
ENST00000417091.5
ENST00000429192.5
ENST00000252034.12
ENST00000442310.5
ENST00000380553.8
ENST00000380576.9
ENST00000428787.5
ENST00000320399.10
elastin
chr1_+_22451843 7.32 ENST00000375647.5
ENST00000404138.5
ENST00000374651.8
ENST00000400239.6
zinc finger and BTB domain containing 40
chr15_-_70763539 7.18 ENST00000322954.11
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr2_-_201071579 7.13 ENST00000453765.5
ENST00000452799.5
ENST00000446678.5
ENST00000418596.7
ENST00000681958.1
family with sequence similarity 126 member B
chr2_-_25252251 7.08 ENST00000380746.8
ENST00000402667.1
DNA methyltransferase 3 alpha
chr7_+_43112593 7.06 ENST00000453890.5
ENST00000395891.7
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr3_-_115071333 6.94 ENST00000462705.5
zinc finger and BTB domain containing 20
chr22_-_20016807 6.94 ENST00000263207.8
ARVCF delta catenin family member
chr5_-_72507354 6.89 ENST00000414109.2
ENST00000318442.6
zinc finger protein 366
chr2_+_15940537 6.79 ENST00000281043.4
ENST00000638417.1
MYCN proto-oncogene, bHLH transcription factor
chr20_-_40689228 6.72 ENST00000373313.3
MAF bZIP transcription factor B
chr6_-_28252246 6.51 ENST00000377294.3
zinc finger with KRAB and SCAN domains 4
chr10_-_11611754 6.44 ENST00000609104.5
USP6 N-terminal like
chr1_-_16352420 6.43 ENST00000375592.8
F-box protein 42
chr8_-_81112055 6.37 ENST00000220597.4
phosphoprotein membrane anchor with glycosphingolipid microdomains 1
chr11_-_117316230 6.36 ENST00000313005.11
ENST00000528053.5
beta-secretase 1
chr12_+_8914698 6.34 ENST00000433083.6
ENST00000544539.5
ENST00000539063.5
polyhomeotic homolog 1
chr16_-_68448491 6.31 ENST00000561749.1
ENST00000219334.10
sphingomyelin phosphodiesterase 3
chr15_-_78811415 6.30 ENST00000388820.5
ADAM metallopeptidase with thrombospondin type 1 motif 7
chrX_+_129982610 6.28 ENST00000218147.11
ENST00000540052.6
BCL6 corepressor like 1
chr1_-_147172456 6.28 ENST00000254101.4
protein kinase AMP-activated non-catalytic subunit beta 2
chr12_-_48004467 6.20 ENST00000380518.8
collagen type II alpha 1 chain
chr19_+_4007714 6.18 ENST00000262971.3
protein inhibitor of activated STAT 4
chr5_-_132963621 6.13 ENST00000265343.10
AF4/FMR2 family member 4
chr6_-_34146080 6.08 ENST00000538487.7
ENST00000374181.8
glutamate metabotropic receptor 4
chr7_-_130440848 6.04 ENST00000675803.1
ENST00000223208.10
ENST00000343969.10
ENST00000471201.6
ENST00000675649.1
ENST00000675168.1
ENST00000469826.2
ENST00000334451.6
ENST00000675962.1
ENST00000675563.1
ENST00000480206.2
ENST00000489512.5
ENST00000676243.1
ENST00000674539.1
ENST00000675935.1
centrosomal protein 41
chr3_-_183825513 6.03 ENST00000318631.8
ENST00000431348.1
MAP6 domain containing 1
chr5_+_177133741 5.98 ENST00000439151.7
nuclear receptor binding SET domain protein 1
chr6_+_30557287 5.98 ENST00000376560.8
proline rich 3
chr2_+_210477676 5.98 ENST00000673510.1
ENST00000673630.1
ENST00000430249.7
carbamoyl-phosphate synthase 1
chr19_+_47713412 5.98 ENST00000538399.1
ENST00000263277.8
EH domain containing 2
chr11_-_66568524 5.97 ENST00000679160.1
ENST00000678305.1
ENST00000310325.10
ENST00000677896.1
ENST00000677587.1
ENST00000679347.1
ENST00000677005.1
ENST00000678872.1
ENST00000679024.1
ENST00000678471.1
ENST00000524994.6
cathepsin F
chr6_-_79947541 5.96 ENST00000369816.5
ELOVL fatty acid elongase 4
chr10_+_119029711 5.95 ENST00000425699.3
nanos C2HC-type zinc finger 1
chr14_+_32939243 5.94 ENST00000346562.6
ENST00000548645.5
ENST00000356141.8
ENST00000357798.9
neuronal PAS domain protein 3
chr12_-_101210232 5.91 ENST00000536262.3
solute carrier family 5 member 8
chr6_-_90296824 5.90 ENST00000257749.9
BTB domain and CNC homolog 2
chr17_-_15262537 5.89 ENST00000395936.7
ENST00000675819.1
ENST00000674707.1
ENST00000675854.1
ENST00000426385.4
ENST00000395938.7
ENST00000612492.5
ENST00000675808.1
peripheral myelin protein 22
chr1_-_37554277 5.88 ENST00000296215.8
Smad nuclear interacting protein 1
chr9_-_37465402 5.86 ENST00000307750.5
zinc finger and BTB domain containing 5
chr18_+_33578213 5.86 ENST00000681521.1
ENST00000269197.12
ASXL transcriptional regulator 3
chr10_+_17752185 5.79 ENST00000377495.2
transmembrane protein 236
chr15_-_33067884 5.72 ENST00000334528.13
formin 1
chr15_+_79432330 5.69 ENST00000305428.8
membrane integral NOTCH2 associated receptor 1
chr16_-_70685975 5.69 ENST00000338779.11
MTSS I-BAR domain containing 2
chr15_-_85794902 5.66 ENST00000337975.6
kelch like family member 25
chr12_+_112125531 5.62 ENST00000549358.5
ENST00000257604.9
ENST00000548092.5
ENST00000412615.7
ENST00000552896.1
TRAF-type zinc finger domain containing 1
chr15_-_34754989 5.59 ENST00000290374.5
gap junction protein delta 2
chr1_-_31239880 5.56 ENST00000373736.7
sodium/potassium transporting ATPase interacting 1
chr6_-_30075767 5.56 ENST00000244360.8
ENST00000376751.8
ring finger protein 39
chr10_+_102918276 5.48 ENST00000369878.9
ENST00000369875.3
cyclin and CBS domain divalent metal cation transport mediator 2
chr3_-_190322434 5.47 ENST00000295522.4
claudin 1
chr2_-_206086057 5.46 ENST00000403263.6
INO80 complex subunit D
chr1_-_72282457 5.41 ENST00000357731.10
neuronal growth regulator 1
chr2_-_27263034 5.39 ENST00000233535.9
solute carrier family 30 member 3
chr14_-_77457554 5.35 ENST00000343765.6
ENST00000327028.8
ENST00000556412.4
ENST00000557466.1
ENST00000448935.6
ENST00000557658.6
ENST00000553888.5
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
chr1_+_11273188 5.31 ENST00000376810.6
UbiA prenyltransferase domain containing 1
chr5_-_179345423 5.24 ENST00000518335.3
ENST00000274609.5
ENST00000251582.12
ADAM metallopeptidase with thrombospondin type 1 motif 2
chr12_+_123384078 5.24 ENST00000402868.8
lysine methyltransferase 5A
chr1_+_203305510 5.24 ENST00000290551.5
BTG anti-proliferation factor 2
chr3_-_57165332 5.24 ENST00000296318.12
interleukin 17 receptor D
chr10_-_80289647 5.15 ENST00000372213.8
methionine adenosyltransferase 1A
chr17_+_18039370 5.14 ENST00000268719.9
ENST00000376345.3
GID complex subunit 4 homolog
chr5_-_123036664 5.14 ENST00000306442.5
peptidylprolyl isomerase C
chr6_-_109094819 5.11 ENST00000436639.6
sestrin 1
chr14_+_64465491 5.09 ENST00000394718.4
A-kinase anchoring protein 5
chr17_-_65056659 5.08 ENST00000439174.7
G protein subunit alpha 13
chr5_+_96936071 5.07 ENST00000231368.10
leucyl and cystinyl aminopeptidase
chr10_-_126388455 5.03 ENST00000368679.8
ENST00000368676.8
ENST00000448723.2
ADAM metallopeptidase domain 12
chrY_+_12904860 4.99 ENST00000336079.8
DEAD-box helicase 3 Y-linked
chr4_+_112145445 4.96 ENST00000309733.6
family with sequence similarity 241 member A
chr5_-_147453888 4.95 ENST00000398514.7
dihydropyrimidinase like 3
chr21_-_26967057 4.86 ENST00000284987.6
ADAM metallopeptidase with thrombospondin type 1 motif 5
chr12_-_116881431 4.85 ENST00000257572.5
harakiri, BCL2 interacting protein
chr10_+_73998104 4.83 ENST00000372755.7
ENST00000211998.10
vinculin
chr19_+_4969105 4.78 ENST00000611640.4
ENST00000159111.9
ENST00000588337.5
ENST00000381759.8
lysine demethylase 4B
chr8_-_23404076 4.77 ENST00000524168.1
ENST00000389131.8
ENST00000523833.2
ENST00000519243.1
lysyl oxidase like 2
chr7_-_138981307 4.77 ENST00000440172.5
ENST00000422774.2
KIAA1549
chr10_-_103855406 4.77 ENST00000355946.6
ENST00000369774.8
SH3 and PX domains 2A
chrX_+_24149629 4.75 ENST00000428571.5
ENST00000539115.5
zinc finger protein X-linked
chr16_+_590056 4.74 ENST00000248139.8
ENST00000568586.5
ENST00000538492.5
RAB40C, member RAS oncogene family
chr7_+_17298642 4.74 ENST00000242057.9
aryl hydrocarbon receptor
chr9_+_104764113 4.69 ENST00000374762.4
nipsnap homolog 3B
chr7_-_6272575 4.69 ENST00000350796.8
cytohesin 3
chr11_-_119729158 4.64 ENST00000264025.8
nectin cell adhesion molecule 1
chr10_-_49539112 4.62 ENST00000355832.10
ENST00000447839.7
ERCC excision repair 6, chromatin remodeling factor
chr1_+_52602347 4.61 ENST00000361314.5
glutathione peroxidase 7
chr8_+_74824526 4.60 ENST00000649643.1
ENST00000260113.7
peptidase inhibitor 15
chr1_+_183023409 4.54 ENST00000258341.5
laminin subunit gamma 1
chr14_+_69398683 4.52 ENST00000556605.5
ENST00000031146.8
ENST00000336643.10
solute carrier family 39 member 9
chr12_+_8032692 4.51 ENST00000162391.8
forkhead box J2
chr9_+_126805003 4.46 ENST00000449886.5
ENST00000450858.1
ENST00000373464.5
zinc finger and BTB domain containing 43
chr6_-_56247525 4.41 ENST00000244728.10
collagen type XXI alpha 1 chain
chr3_-_142448060 4.39 ENST00000264951.8
5'-3' exoribonuclease 1
chr12_+_69470349 4.36 ENST00000547219.5
ENST00000550316.5
ENST00000548154.5
ENST00000547414.5
ENST00000549921.6
ENST00000550389.5
ENST00000550937.5
ENST00000549092.5
ENST00000550169.5
fibroblast growth factor receptor substrate 2
chr5_-_177554545 4.36 ENST00000514747.6
family with sequence similarity 193 member B
chr1_+_15617415 4.35 ENST00000480945.6
DNA damage inducible 1 homolog 2
chr10_-_931684 4.32 ENST00000316157.8
La ribonucleoprotein 4B
chr5_+_111224374 4.32 ENST00000282356.9
calcium/calmodulin dependent protein kinase IV
chr9_-_21335340 4.31 ENST00000359039.5
kelch like family member 9
chr8_+_1823967 4.24 ENST00000520359.5
ENST00000518288.5
Rho guanine nucleotide exchange factor 10
chr8_+_133191060 4.21 ENST00000519433.1
ENST00000517423.5
ENST00000220856.6
cellular communication network factor 4
chrX_+_9786420 4.18 ENST00000380913.8
shroom family member 2
chr10_+_100462969 4.16 ENST00000343737.6
Wnt family member 8B
chr3_+_99638475 4.16 ENST00000452013.5
ENST00000261037.7
ENST00000652472.1
ENST00000273342.8
ENST00000621757.1
collagen type VIII alpha 1 chain
chr10_-_73874502 4.13 ENST00000372765.5
ENST00000351293.7
ENST00000441192.2
ENST00000423381.6
calcium/calmodulin dependent protein kinase II gamma
chr17_-_4263847 4.13 ENST00000570535.5
ENST00000574367.5
ENST00000341657.9
ankyrin repeat and FYVE domain containing 1
chrX_+_120362079 4.10 ENST00000539306.5
ENST00000218008.8
ENST00000361319.3
ATPase Na+/K+ transporting family member beta 4
chr16_-_10580577 4.09 ENST00000359543.8
epithelial membrane protein 2
chr15_+_73684373 4.09 ENST00000558689.5
ENST00000560786.6
ENST00000318443.10
ENST00000561213.5
CD276 molecule
chr9_-_112333603 4.05 ENST00000450374.1
ENST00000374257.6
ENST00000374255.6
ENST00000334318.10
polypyrimidine tract binding protein 3
chr4_-_152536045 4.04 ENST00000603548.6
ENST00000281708.10
F-box and WD repeat domain containing 7
chr14_-_93333015 4.01 ENST00000334746.10
ENST00000554565.5
ENST00000298896.7
BTB domain containing 7
chr12_-_12267003 3.98 ENST00000535731.1
ENST00000261349.9
LDL receptor related protein 6

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
9.8 49.1 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
8.1 24.3 GO:2000591 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
6.4 32.0 GO:2000542 negative regulation of gastrulation(GO:2000542)
6.2 37.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
4.8 19.4 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
4.8 19.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
4.7 14.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
4.4 4.4 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
3.6 21.7 GO:0033591 response to L-ascorbic acid(GO:0033591)
3.6 32.4 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
3.5 45.7 GO:0043589 skin morphogenesis(GO:0043589)
3.2 12.7 GO:0071409 cellular response to cycloheximide(GO:0071409)
2.6 29.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
2.6 12.9 GO:0035582 sequestering of BMP in extracellular matrix(GO:0035582)
2.5 10.1 GO:0086097 phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
2.4 12.1 GO:1901906 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
2.3 32.9 GO:0038065 collagen-activated signaling pathway(GO:0038065)
2.2 13.0 GO:0022027 interkinetic nuclear migration(GO:0022027)
2.0 12.0 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
2.0 6.0 GO:1903718 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) cellular response to oleic acid(GO:0071400) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
2.0 8.0 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
2.0 9.8 GO:0097167 circadian regulation of translation(GO:0097167)
1.8 5.5 GO:0008065 establishment of blood-nerve barrier(GO:0008065) cellular response to lead ion(GO:0071284) positive regulation of bicellular tight junction assembly(GO:1903348)
1.7 3.4 GO:0036166 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
1.7 6.7 GO:0021571 rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
1.7 16.8 GO:1901538 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
1.6 4.8 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
1.5 14.8 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
1.4 5.7 GO:0072092 ureteric bud invasion(GO:0072092)
1.4 50.8 GO:0030199 collagen fibril organization(GO:0030199)
1.3 4.0 GO:2000053 Wnt signaling pathway involved in somitogenesis(GO:0090244) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
1.3 3.9 GO:0045829 negative regulation of isotype switching(GO:0045829)
1.2 7.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
1.2 3.6 GO:0100009 circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
1.2 8.1 GO:0035879 plasma membrane lactate transport(GO:0035879)
1.2 13.9 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
1.2 3.5 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
1.1 2.3 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
1.1 11.2 GO:0036066 protein O-linked fucosylation(GO:0036066)
1.1 13.2 GO:0043587 tongue morphogenesis(GO:0043587)
1.1 17.4 GO:0045116 protein neddylation(GO:0045116)
1.1 7.5 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
1.1 7.5 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
1.1 5.3 GO:0009233 menaquinone metabolic process(GO:0009233)
1.0 8.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
1.0 3.1 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
1.0 3.1 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
1.0 3.0 GO:0072709 cellular response to sorbitol(GO:0072709)
1.0 9.6 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
1.0 2.9 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.9 16.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.9 2.7 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of osteoclast proliferation(GO:0090291)
0.9 2.7 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.9 6.2 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.9 6.0 GO:0018095 protein polyglutamylation(GO:0018095)
0.9 6.0 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.8 1.7 GO:1901859 negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.8 2.5 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.8 2.5 GO:1904580 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.8 2.4 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.8 4.0 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.8 7.9 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.8 3.1 GO:0019086 late viral transcription(GO:0019086)
0.8 6.0 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.7 6.0 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.7 2.2 GO:0044805 late nucleophagy(GO:0044805)
0.7 3.6 GO:0061743 motor learning(GO:0061743)
0.7 3.5 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.7 9.1 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.7 2.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.7 4.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.7 2.1 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.6 2.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.6 9.0 GO:0036158 outer dynein arm assembly(GO:0036158)
0.6 43.8 GO:0030574 collagen catabolic process(GO:0030574)
0.6 11.1 GO:0032060 bleb assembly(GO:0032060)
0.6 7.9 GO:0032836 glomerular basement membrane development(GO:0032836)
0.6 3.0 GO:0072014 proximal tubule development(GO:0072014)
0.6 4.2 GO:0048263 determination of dorsal identity(GO:0048263)
0.6 4.6 GO:0070166 enamel mineralization(GO:0070166)
0.6 4.6 GO:0007256 activation of JNKK activity(GO:0007256)
0.6 6.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.6 5.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.5 2.2 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.5 17.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.5 4.2 GO:0045176 apical protein localization(GO:0045176)
0.5 2.0 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.5 5.1 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.5 11.1 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.5 5.6 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.5 1.5 GO:0051230 mitotic spindle disassembly(GO:0051228) spindle disassembly(GO:0051230)
0.5 7.5 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.5 6.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.5 3.4 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.5 6.8 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.5 4.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.5 4.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.4 5.3 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.4 4.3 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.4 1.3 GO:0044332 Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
0.4 5.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.4 3.7 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.4 1.6 GO:0035627 ceramide transport(GO:0035627)
0.4 3.1 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.4 6.7 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.4 3.9 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.4 4.9 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.4 2.6 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.4 8.3 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.4 1.4 GO:0032455 nerve growth factor processing(GO:0032455)
0.4 6.1 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.4 2.5 GO:2000698 positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.4 1.4 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.4 0.7 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.3 11.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.3 5.9 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.3 5.5 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.3 4.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.3 5.2 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.3 3.5 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633)
0.3 1.2 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.3 1.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.3 14.0 GO:0015804 neutral amino acid transport(GO:0015804)
0.3 3.2 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 6.3 GO:0006853 carnitine shuttle(GO:0006853)
0.3 1.7 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.3 3.9 GO:0015074 DNA integration(GO:0015074)
0.3 2.2 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.3 3.5 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.3 2.4 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.3 4.5 GO:0070831 basement membrane assembly(GO:0070831)
0.3 2.4 GO:0001661 conditioned taste aversion(GO:0001661)
0.3 1.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3 2.1 GO:0015886 heme transport(GO:0015886)
0.3 4.9 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.3 1.3 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.2 1.2 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.2 8.0 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.2 2.5 GO:1902592 viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.2 1.0 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.2 5.8 GO:0033622 integrin activation(GO:0033622)
0.2 4.5 GO:0006829 zinc II ion transport(GO:0006829)
0.2 9.2 GO:0009303 rRNA transcription(GO:0009303)
0.2 10.6 GO:0006198 cAMP catabolic process(GO:0006198)
0.2 10.2 GO:0016266 O-glycan processing(GO:0016266)
0.2 2.5 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.2 1.8 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 0.7 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.2 4.1 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.2 4.5 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.2 7.5 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.2 3.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.2 4.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.2 2.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.2 4.9 GO:0051764 actin crosslink formation(GO:0051764)
0.2 3.5 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.2 6.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.2 8.9 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.2 2.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.2 2.9 GO:0038092 nodal signaling pathway(GO:0038092)
0.2 4.4 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.2 3.2 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.2 0.5 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.2 10.0 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.2 2.6 GO:0097264 self proteolysis(GO:0097264)
0.2 0.9 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2 0.8 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.2 21.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 1.8 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 6.6 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.1 3.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 2.7 GO:0022038 corpus callosum development(GO:0022038)
0.1 0.8 GO:0044331 cell-cell adhesion mediated by cadherin(GO:0044331)
0.1 3.2 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.1 2.9 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.1 2.2 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.1 1.7 GO:2000394 positive regulation of lamellipodium morphogenesis(GO:2000394)
0.1 3.4 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.1 8.8 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.1 1.4 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.1 1.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 10.6 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.1 4.0 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 0.9 GO:0060536 cartilage morphogenesis(GO:0060536)
0.1 1.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 6.9 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.1 5.9 GO:0021762 substantia nigra development(GO:0021762)
0.1 0.9 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 5.6 GO:0045824 negative regulation of innate immune response(GO:0045824)
0.1 4.6 GO:0046473 phosphatidic acid metabolic process(GO:0046473)
0.1 3.0 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 0.8 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.1 4.7 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.1 2.3 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1 0.7 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 1.9 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.1 1.0 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.1 0.7 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.4 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.1 1.2 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 12.1 GO:0042594 response to starvation(GO:0042594)
0.1 4.8 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 0.7 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 14.5 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.1 20.3 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.1 5.2 GO:0006826 iron ion transport(GO:0006826)
0.1 0.2 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.1 7.2 GO:0030282 bone mineralization(GO:0030282)
0.1 5.1 GO:0050868 negative regulation of T cell activation(GO:0050868)
0.1 0.3 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.1 2.6 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 3.2 GO:0010107 potassium ion import(GO:0010107)
0.1 4.6 GO:0098869 cellular oxidant detoxification(GO:0098869)
0.1 2.5 GO:1901998 toxin transport(GO:1901998)
0.1 0.6 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
0.1 3.1 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.1 6.8 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1 0.8 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.1 2.8 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.1 0.7 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.1 1.7 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.1 2.6 GO:0002209 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.1 3.2 GO:0021549 cerebellum development(GO:0021549)
0.1 0.8 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.6 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 2.4 GO:0006730 one-carbon metabolic process(GO:0006730)
0.0 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 2.6 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 5.9 GO:0001508 action potential(GO:0001508)
0.0 0.2 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 2.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.1 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0 2.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 2.2 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 1.4 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 2.4 GO:0035176 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 1.8 GO:0048477 oogenesis(GO:0048477)
0.0 5.0 GO:0006661 phosphatidylinositol biosynthetic process(GO:0006661)
0.0 1.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.6 GO:0001706 endoderm formation(GO:0001706)
0.0 1.1 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.2 GO:0030238 male sex determination(GO:0030238)
0.0 0.2 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 2.3 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
0.0 0.1 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.7 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 1.3 GO:0060041 retina development in camera-type eye(GO:0060041)
0.0 0.5 GO:0051031 tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.9 GO:0000910 cytokinesis(GO:0000910)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
13.2 39.5 GO:0005588 collagen type V trimer(GO:0005588)
11.4 113.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
4.7 52.0 GO:0098651 basement membrane collagen trimer(GO:0098651)
3.2 13.0 GO:0070695 FHF complex(GO:0070695)
3.2 9.6 GO:0032116 SMC loading complex(GO:0032116)
2.1 6.4 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
1.9 32.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
1.9 7.4 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
1.8 25.4 GO:0098644 complex of collagen trimers(GO:0098644)
1.6 9.7 GO:0001940 male pronucleus(GO:0001940)
1.5 4.5 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
1.3 9.0 GO:0036157 outer dynein arm(GO:0036157)
1.1 9.5 GO:0036449 microtubule minus-end(GO:0036449)
1.1 7.4 GO:0005683 U7 snRNP(GO:0005683)
1.0 5.1 GO:0031905 early endosome lumen(GO:0031905)
1.0 4.0 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
1.0 19.4 GO:0033270 paranode region of axon(GO:0033270)
1.0 8.6 GO:0030897 HOPS complex(GO:0030897)
0.9 7.4 GO:0005593 FACIT collagen trimer(GO:0005593)
0.9 16.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.8 7.3 GO:0071953 elastic fiber(GO:0071953)
0.8 21.7 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.8 4.7 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.8 4.6 GO:0032584 growth cone membrane(GO:0032584)
0.7 6.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.7 2.1 GO:0031251 PAN complex(GO:0031251)
0.6 5.1 GO:0061700 GATOR2 complex(GO:0061700)
0.6 4.1 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.6 37.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.6 4.0 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.6 4.0 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.5 2.7 GO:0044305 calyx of Held(GO:0044305)
0.4 3.5 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.4 3.9 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.4 2.5 GO:0045298 tubulin complex(GO:0045298)
0.4 6.3 GO:0035102 PRC1 complex(GO:0035102)
0.4 2.8 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.4 0.8 GO:0005899 insulin receptor complex(GO:0005899)
0.4 16.3 GO:0000791 euchromatin(GO:0000791)
0.4 4.3 GO:0042788 polysomal ribosome(GO:0042788)
0.3 3.1 GO:0000813 ESCRT I complex(GO:0000813)
0.3 2.4 GO:0035976 AP1 complex(GO:0035976)
0.3 16.5 GO:0005581 collagen trimer(GO:0005581)
0.3 16.4 GO:0031941 filamentous actin(GO:0031941)
0.3 6.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.3 5.6 GO:0005922 connexon complex(GO:0005922)
0.3 4.0 GO:0097431 mitotic spindle pole(GO:0097431)
0.3 3.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.3 4.8 GO:0005916 fascia adherens(GO:0005916)
0.3 3.0 GO:0005915 zonula adherens(GO:0005915)
0.2 2.0 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 8.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.2 6.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 0.9 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.2 24.5 GO:0005901 caveola(GO:0005901)
0.2 4.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.2 7.9 GO:0005605 basal lamina(GO:0005605)
0.2 2.4 GO:0030870 Mre11 complex(GO:0030870)
0.2 2.1 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.2 63.6 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 2.5 GO:0005845 mRNA cap binding complex(GO:0005845)
0.2 2.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.2 2.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 2.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.2 23.6 GO:0005923 bicellular tight junction(GO:0005923)
0.2 1.4 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 3.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 8.2 GO:0031904 endosome lumen(GO:0031904)
0.1 33.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 2.6 GO:0031045 dense core granule(GO:0031045)
0.1 1.8 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 7.1 GO:0005801 cis-Golgi network(GO:0005801)
0.1 12.3 GO:0043202 lysosomal lumen(GO:0043202)
0.1 4.8 GO:0002102 podosome(GO:0002102)
0.1 1.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 2.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 9.4 GO:0005884 actin filament(GO:0005884)
0.1 2.5 GO:0031528 microvillus membrane(GO:0031528)
0.1 1.6 GO:0044291 cell-cell contact zone(GO:0044291)
0.1 1.3 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 0.8 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 1.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 2.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 4.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 5.1 GO:0031526 brush border membrane(GO:0031526)
0.1 1.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 9.3 GO:0055037 recycling endosome(GO:0055037)
0.1 0.9 GO:0000815 ESCRT III complex(GO:0000815)
0.1 5.5 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 1.1 GO:0097440 apical dendrite(GO:0097440)
0.1 0.7 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 8.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 22.6 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 1.4 GO:0030057 desmosome(GO:0030057)
0.1 1.7 GO:0031594 neuromuscular junction(GO:0031594)
0.1 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 1.8 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 6.9 GO:0005814 centriole(GO:0005814)
0.1 2.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 3.1 GO:0005903 brush border(GO:0005903)
0.0 6.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 5.1 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 5.0 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.0 3.2 GO:0030666 endocytic vesicle membrane(GO:0030666)
0.0 73.8 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 3.8 GO:0008021 synaptic vesicle(GO:0008021)
0.0 5.4 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 4.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 3.3 GO:0010008 endosome membrane(GO:0010008)
0.0 1.7 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.2 GO:0016459 myosin complex(GO:0016459)
0.0 5.3 GO:0043025 neuronal cell body(GO:0043025)
0.0 0.2 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 4.7 GO:0005813 centrosome(GO:0005813)
0.0 10.5 GO:0005615 extracellular space(GO:0005615)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
12.7 164.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
5.6 16.9 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
3.7 14.8 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
3.7 11.0 GO:0030350 iron-responsive element binding(GO:0030350)
3.5 17.3 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
2.9 11.7 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
2.9 8.6 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
2.5 7.4 GO:0008502 melatonin receptor activity(GO:0008502)
2.4 12.1 GO:0052846 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
2.3 9.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
2.1 12.9 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
2.0 10.1 GO:0010861 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
1.7 10.2 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
1.7 8.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
1.6 19.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
1.6 6.4 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
1.5 12.0 GO:0038064 collagen receptor activity(GO:0038064)
1.5 6.0 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
1.4 14.1 GO:0001042 RNA polymerase I core binding(GO:0001042)
1.4 12.3 GO:0004565 beta-galactosidase activity(GO:0004565)
1.3 4.0 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
1.3 7.9 GO:0043237 laminin-1 binding(GO:0043237)
1.3 7.9 GO:0008142 oxysterol binding(GO:0008142)
1.3 9.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
1.2 7.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
1.1 7.5 GO:0002114 interleukin-33 receptor activity(GO:0002114)
1.0 6.2 GO:0061665 SUMO ligase activity(GO:0061665)
1.0 8.6 GO:0004969 histamine receptor activity(GO:0004969)
0.9 78.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.9 5.1 GO:0070728 leucine binding(GO:0070728)
0.8 2.5 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.8 4.0 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.8 3.0 GO:0035939 microsatellite binding(GO:0035939)
0.7 5.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.7 6.0 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.7 14.0 GO:0097602 cullin family protein binding(GO:0097602)
0.7 6.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.7 2.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.7 4.8 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.6 9.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.6 1.8 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.6 2.9 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.6 3.5 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.5 9.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.5 4.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.5 5.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.5 2.5 GO:0046935 phosphatidylinositol 3-kinase regulator activity(GO:0035014) 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.5 4.9 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.5 2.5 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.5 5.9 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.5 10.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.5 1.9 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.5 4.8 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.5 5.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.4 3.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.4 6.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.4 5.3 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.4 1.7 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.4 2.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.4 1.6 GO:0017089 glycolipid transporter activity(GO:0017089) ceramide binding(GO:0097001)
0.4 11.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.4 8.9 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.4 5.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.4 3.1 GO:0043426 MRF binding(GO:0043426)
0.4 50.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.4 8.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.4 4.6 GO:0046790 virion binding(GO:0046790)
0.4 5.6 GO:0005243 gap junction channel activity(GO:0005243)
0.4 1.8 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.3 1.4 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.3 4.1 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.3 3.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.3 1.7 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.3 14.0 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.3 34.3 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 1.0 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.3 5.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.3 1.9 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.3 5.1 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.3 3.4 GO:0015266 protein channel activity(GO:0015266) BH3 domain binding(GO:0051434)
0.3 2.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.3 0.8 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.3 2.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.3 6.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.3 2.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.3 17.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.3 4.8 GO:0045294 alpha-catenin binding(GO:0045294)
0.2 10.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.2 4.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 9.7 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.2 3.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.2 5.3 GO:0004659 prenyltransferase activity(GO:0004659)
0.2 1.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.2 1.7 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.2 2.8 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.2 10.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 2.7 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 0.6 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 3.6 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 12.2 GO:0070888 E-box binding(GO:0070888)
0.2 6.1 GO:0008066 glutamate receptor activity(GO:0008066)
0.2 1.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 5.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.2 1.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.2 3.2 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 1.0 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.2 7.4 GO:0017069 snRNA binding(GO:0017069)
0.2 3.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.2 7.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 2.8 GO:0097016 L27 domain binding(GO:0097016)
0.2 3.1 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 5.8 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.2 2.4 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 17.5 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 0.7 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.1 3.1 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 4.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 5.9 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 4.2 GO:0005109 frizzled binding(GO:0005109)
0.1 3.3 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 4.6 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 2.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 5.8 GO:0070412 R-SMAD binding(GO:0070412)
0.1 1.8 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 0.8 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 3.4 GO:0071837 HMG box domain binding(GO:0071837)
0.1 3.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 1.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 2.7 GO:0005003 ephrin receptor activity(GO:0005003)
0.1 1.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 2.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 25.2 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1 17.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 10.0 GO:0001618 virus receptor activity(GO:0001618)
0.1 6.3 GO:0019894 kinesin binding(GO:0019894)
0.1 21.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 2.4 GO:0030371 translation repressor activity(GO:0030371)
0.1 2.1 GO:0001221 transcription cofactor binding(GO:0001221)
0.1 3.0 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 1.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 2.5 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.1 3.0 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 3.4 GO:0005158 insulin receptor binding(GO:0005158)
0.1 1.0 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 2.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 2.4 GO:0030332 cyclin binding(GO:0030332)
0.1 26.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 10.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 2.2 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.1 2.5 GO:0042805 actinin binding(GO:0042805)
0.1 9.8 GO:0008201 heparin binding(GO:0008201)
0.1 14.4 GO:0005516 calmodulin binding(GO:0005516)
0.1 0.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195) lipid phosphatase activity(GO:0042577)
0.1 6.1 GO:0017124 SH3 domain binding(GO:0017124)
0.1 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 4.7 GO:0051117 ATPase binding(GO:0051117)
0.0 4.3 GO:0043130 ubiquitin binding(GO:0043130)
0.0 42.2 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 2.2 GO:0008200 ion channel inhibitor activity(GO:0008200) channel inhibitor activity(GO:0016248)
0.0 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 1.8 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 5.6 GO:0051015 actin filament binding(GO:0051015)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.7 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 1.4 GO:0015297 antiporter activity(GO:0015297)
0.0 0.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 1.1 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.4 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 10.8 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.7 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 242.2 NABA COLLAGENS Genes encoding collagen proteins
1.4 5.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.9 2.8 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.7 45.3 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.5 9.8 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.5 28.0 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.4 22.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.4 14.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.4 8.7 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.4 5.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.3 7.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.3 51.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.3 7.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.3 5.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 6.4 PID BCR 5PATHWAY BCR signaling pathway
0.2 10.5 PID IL1 PATHWAY IL1-mediated signaling events
0.2 5.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.2 9.0 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.2 9.1 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.2 52.8 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2 6.5 PID IL27 PATHWAY IL27-mediated signaling events
0.2 11.8 PID FGF PATHWAY FGF signaling pathway
0.1 9.1 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 5.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.7 PID EPHB FWD PATHWAY EPHB forward signaling
0.1 3.0 PID P53 REGULATION PATHWAY p53 pathway
0.1 20.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 5.8 NABA CORE MATRISOME Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.1 3.2 PID RHOA PATHWAY RhoA signaling pathway
0.1 1.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 14.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 1.7 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 2.2 PID TRAIL PATHWAY TRAIL signaling pathway
0.1 2.7 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 3.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 4.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 3.8 PID ARF6 PATHWAY Arf6 signaling events
0.1 2.5 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 3.9 PID AURORA B PATHWAY Aurora B signaling
0.1 6.5 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.1 4.7 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.1 3.4 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 3.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 5.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 1.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 1.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 1.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.7 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 3.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.6 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 259.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
1.0 25.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.0 16.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.9 5.2 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.7 9.9 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.7 16.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.5 8.1 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.5 7.4 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.5 4.4 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events
0.5 13.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.5 5.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.4 8.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.4 12.7 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.4 4.3 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.4 0.8 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.4 2.2 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.3 6.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.3 8.8 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.3 5.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.3 6.8 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.3 15.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.3 6.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 5.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.3 8.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.3 6.4 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.3 7.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.2 4.9 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.2 8.3 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.2 8.6 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 6.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 9.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 9.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.2 7.8 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.2 6.0 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2 10.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.2 5.9 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.2 17.1 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.2 3.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.2 3.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.2 5.1 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.2 2.4 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 9.4 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.1 6.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 11.6 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 13.7 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 15.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 5.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 3.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 4.6 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1 1.8 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 2.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 1.6 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 2.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.8 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.1 3.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 1.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 1.4 REACTOME SIGNALLING BY NGF Genes involved in Signalling by NGF
0.1 1.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 2.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 2.4 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 2.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.7 REACTOME CD28 CO STIMULATION Genes involved in CD28 co-stimulation
0.0 0.8 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 8.1 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 1.5 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 1.2 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac