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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for AGCAGCG

Z-value: 0.81

Motif logo

logo of

miRNA associated with seed AGCAGCG

NamemiRBASE accession
hsa-miR-503-5p
MIMAT0002874

Activity profile of AGCAGCG motif

Sorted Z-values of AGCAGCG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AGCAGCG

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr12_+_4273751 3.48 ENST00000675880.1
ENST00000261254.8
CCND2
cyclin D2
chr2_+_112275588 3.41 ENST00000409871.6
ENST00000343936.4
ZC3H6
zinc finger CCCH-type containing 6
chr8_+_23528947 3.12 ENST00000519973.6
SLC25A37
solute carrier family 25 member 37
chr20_+_50731571 2.82 ENST00000371610.7
PARD6B
par-6 family cell polarity regulator beta
chr9_-_92670124 2.77 ENST00000287996.8
IPPK
inositol-pentakisphosphate 2-kinase
chr9_-_27529705 2.71 ENST00000262244.6
MOB3B
MOB kinase activator 3B
chr9_+_36036899 2.61 ENST00000377966.4
RECK
reversion inducing cysteine rich protein with kazal motifs
chr1_+_77779618 2.56 ENST00000370791.7
ENST00000443751.3
ENST00000645756.1
ENST00000643390.1
ENST00000642959.1
MIGA1
mitoguardin 1
chr18_+_70288991 2.16 ENST00000397942.4
SOCS6
suppressor of cytokine signaling 6
chr11_-_119729158 2.16 ENST00000264025.8
NECTIN1
nectin cell adhesion molecule 1
chr18_+_57352541 2.11 ENST00000324000.4
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr2_+_28392802 2.07 ENST00000379619.5
ENST00000264716.9
FOSL2
FOS like 2, AP-1 transcription factor subunit
chr9_+_116153783 2.05 ENST00000328252.4
PAPPA
pappalysin 1
chr9_-_109320949 1.93 ENST00000374557.4
EPB41L4B
erythrocyte membrane protein band 4.1 like 4B
chr3_+_38453832 1.91 ENST00000352511.5
ACVR2B
activin A receptor type 2B
chr10_+_110871903 1.88 ENST00000280154.12
PDCD4
programmed cell death 4
chr2_-_219060914 1.87 ENST00000295731.7
IHH
Indian hedgehog signaling molecule
chr10_+_101354083 1.74 ENST00000408038.6
ENST00000370187.8
BTRC
beta-transducin repeat containing E3 ubiquitin protein ligase
chr10_-_118754956 1.74 ENST00000369151.8
CACUL1
CDK2 associated cullin domain 1
chr3_-_123884290 1.73 ENST00000346322.9
ENST00000360772.7
ENST00000360304.8
MYLK
myosin light chain kinase
chr7_+_139231225 1.69 ENST00000473989.8
UBN2
ubinuclein 2
chr16_+_67893244 1.69 ENST00000291041.6
ENST00000570631.5
PSKH1
protein serine kinase H1
chr15_+_74173693 1.65 ENST00000249842.8
ISLR
immunoglobulin superfamily containing leucine rich repeat
chrX_+_118974608 1.62 ENST00000304778.11
ENST00000371628.8
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr19_-_17688326 1.62 ENST00000552293.5
ENST00000551649.5
ENST00000519716.7
ENST00000550896.1
UNC13A
unc-13 homolog A
chr6_+_41072939 1.58 ENST00000341376.11
ENST00000353205.5
NFYA
nuclear transcription factor Y subunit alpha
chr3_-_120450981 1.51 ENST00000424703.6
ENST00000469005.1
ENST00000295633.8
FSTL1
follistatin like 1
chr16_+_69187125 1.50 ENST00000336278.8
SNTB2
syntrophin beta 2
chr16_-_88941198 1.49 ENST00000327483.9
ENST00000564416.1
CBFA2T3
CBFA2/RUNX1 partner transcriptional co-repressor 3
chr5_+_42423433 1.49 ENST00000230882.9
GHR
growth hormone receptor
chr18_-_63319987 1.46 ENST00000398117.1
BCL2
BCL2 apoptosis regulator
chr4_+_20251896 1.37 ENST00000504154.6
SLIT2
slit guidance ligand 2
chr17_+_60600178 1.36 ENST00000629650.2
ENST00000305921.8
PPM1D
protein phosphatase, Mg2+/Mn2+ dependent 1D
chr12_-_107761113 1.32 ENST00000228437.10
PRDM4
PR/SET domain 4
chr12_-_7872843 1.31 ENST00000340749.9
ENST00000535295.5
ENST00000539234.5
SLC2A14
solute carrier family 2 member 14
chr14_+_24398986 1.30 ENST00000382554.4
NYNRIN
NYN domain and retroviral integrase containing
chr16_-_48610150 1.30 ENST00000262384.4
N4BP1
NEDD4 binding protein 1
chr3_+_122184233 1.29 ENST00000638421.1
ENST00000498619.4
CASR
calcium sensing receptor
chr17_+_79778135 1.26 ENST00000310942.9
ENST00000269399.5
CBX2
chromobox 2
chr4_+_122826679 1.17 ENST00000264498.8
FGF2
fibroblast growth factor 2
chr1_-_52366124 1.17 ENST00000371586.6
ENST00000284376.8
CC2D1B
coiled-coil and C2 domain containing 1B
chr4_+_165873231 1.13 ENST00000061240.7
TLL1
tolloid like 1
chr22_+_45163910 1.12 ENST00000347635.9
ENST00000407019.6
ENST00000424634.5
ENST00000417702.5
ENST00000430547.5
NUP50
nucleoporin 50
chr16_+_30699155 1.09 ENST00000262518.9
SRCAP
Snf2 related CREBBP activator protein
chr16_+_58515474 1.09 ENST00000310682.6
ENST00000394266.8
SETD6
SET domain containing 6, protein lysine methyltransferase
chrX_+_49922605 1.07 ENST00000376088.7
CLCN5
chloride voltage-gated channel 5
chr3_-_13880059 1.06 ENST00000285018.5
WNT7A
Wnt family member 7A
chr7_+_4682252 1.04 ENST00000328914.5
FOXK1
forkhead box K1
chr11_-_61161414 1.03 ENST00000301765.10
VPS37C
VPS37C subunit of ESCRT-I
chr12_+_57550027 0.95 ENST00000674619.1
ENST00000676359.1
ENST00000286452.5
ENST00000455537.7
ENST00000676457.1
KIF5A
kinesin family member 5A
chrX_-_84188148 0.94 ENST00000262752.5
RPS6KA6
ribosomal protein S6 kinase A6
chr6_-_96837460 0.92 ENST00000229955.4
GPR63
G protein-coupled receptor 63
chr4_+_93828746 0.88 ENST00000306011.6
ATOH1
atonal bHLH transcription factor 1
chr11_-_126268810 0.87 ENST00000332118.11
SRPRA
SRP receptor subunit alpha
chr4_-_76023489 0.87 ENST00000306602.3
CXCL10
C-X-C motif chemokine ligand 10
chr12_-_7936177 0.87 ENST00000544291.1
ENST00000075120.12
SLC2A3
solute carrier family 2 member 3
chr10_+_102918276 0.82 ENST00000369878.9
ENST00000369875.3
CNNM2
cyclin and CBS domain divalent metal cation transport mediator 2
chr19_+_46746046 0.81 ENST00000601299.5
ENST00000595570.5
ENST00000598271.5
ENST00000597313.5
ENST00000593875.5
ENST00000391909.7
ENST00000318584.10
ENST00000602250.5
ENST00000595868.5
ENST00000600629.5
ENST00000602181.5
ENST00000593800.5
ENST00000600227.5
ENST00000600005.5
ENST00000594467.5
ENST00000596460.5
FKRP
fukutin related protein
chr2_+_167868948 0.81 ENST00000392690.3
B3GALT1
beta-1,3-galactosyltransferase 1
chr2_-_36966503 0.79 ENST00000263918.9
STRN
striatin
chr17_-_67245165 0.77 ENST00000580168.5
ENST00000358691.10
HELZ
helicase with zinc finger
chr1_-_207051202 0.77 ENST00000315927.9
YOD1
YOD1 deubiquitinase
chr3_+_196867856 0.77 ENST00000445299.6
ENST00000323460.10
ENST00000419026.5
SENP5
SUMO specific peptidase 5
chr3_+_10816201 0.74 ENST00000454147.1
ENST00000254488.7
SLC6A11
solute carrier family 6 member 11
chr10_+_86756580 0.74 ENST00000372037.8
BMPR1A
bone morphogenetic protein receptor type 1A
chr3_-_48188356 0.73 ENST00000351231.7
ENST00000437972.1
ENST00000302506.8
CDC25A
cell division cycle 25A
chr10_-_59906509 0.71 ENST00000263102.7
CCDC6
coiled-coil domain containing 6
chr7_+_72879349 0.71 ENST00000395270.5
POM121
POM121 transmembrane nucleoporin
chr2_+_119759875 0.71 ENST00000263708.7
PTPN4
protein tyrosine phosphatase non-receptor type 4
chr2_-_121285194 0.71 ENST00000263707.6
TFCP2L1
transcription factor CP2 like 1
chr2_-_219543793 0.67 ENST00000243776.11
CHPF
chondroitin polymerizing factor
chr3_-_179071742 0.67 ENST00000311417.7
ENST00000652290.1
ZMAT3
zinc finger matrin-type 3
chr9_-_125143457 0.66 ENST00000373549.8
ENST00000336505.11
SCAI
suppressor of cancer cell invasion
chr8_+_28701487 0.66 ENST00000220562.9
EXTL3
exostosin like glycosyltransferase 3
chr1_+_23959797 0.65 ENST00000374468.1
ENST00000334351.8
PNRC2
proline rich nuclear receptor coactivator 2
chr7_-_99144053 0.64 ENST00000361125.1
ENST00000361368.7
SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr18_-_48950960 0.63 ENST00000262158.8
SMAD7
SMAD family member 7
chr1_+_2228310 0.61 ENST00000378536.5
SKI
SKI proto-oncogene
chr3_+_184315131 0.59 ENST00000427845.5
ENST00000342981.8
EIF4G1
eukaryotic translation initiation factor 4 gamma 1
chr12_+_54497712 0.58 ENST00000293373.11
NCKAP1L
NCK associated protein 1 like
chr19_-_39833615 0.56 ENST00000593685.5
ENST00000600611.5
DYRK1B
dual specificity tyrosine phosphorylation regulated kinase 1B
chr7_-_99438647 0.56 ENST00000430029.1
ENST00000419981.1
ENST00000292478.9
PTCD1
pentatricopeptide repeat domain 1
chr10_+_91923762 0.55 ENST00000265990.11
BTAF1
B-TFIID TATA-box binding protein associated factor 1
chr11_-_74398378 0.55 ENST00000298198.5
PGM2L1
phosphoglucomutase 2 like 1
chr15_+_58771280 0.52 ENST00000559228.6
ENST00000450403.3
MINDY2
MINDY lysine 48 deubiquitinase 2
chr18_-_32470484 0.52 ENST00000399218.8
GAREM1
GRB2 associated regulator of MAPK1 subtype 1
chr11_+_117144277 0.49 ENST00000419197.6
ENST00000527958.6
ENST00000304808.10
ENST00000529887.6
ENST00000530272.1
PAFAH1B2
platelet activating factor acetylhydrolase 1b catalytic subunit 2
chr17_+_48048345 0.49 ENST00000584137.5
ENST00000362042.8
ENST00000585291.5
ENST00000357480.9
NFE2L1
nuclear factor, erythroid 2 like 1
chr2_-_72147819 0.49 ENST00000001146.7
ENST00000546307.5
ENST00000474509.1
CYP26B1
cytochrome P450 family 26 subfamily B member 1
chr20_-_1184473 0.47 ENST00000381894.3
TMEM74B
transmembrane protein 74B
chr20_-_53593829 0.46 ENST00000371471.7
ZNF217
zinc finger protein 217
chr7_-_99408548 0.45 ENST00000626285.1
ENST00000350498.8
PDAP1
PDGFA associated protein 1
chr9_-_35732122 0.45 ENST00000314888.10
TLN1
talin 1
chr17_+_59155726 0.44 ENST00000578777.5
ENST00000577457.1
ENST00000582995.5
ENST00000262293.9
ENST00000614081.1
PRR11
proline rich 11
chr6_+_143608170 0.42 ENST00000427704.6
ENST00000305766.10
PHACTR2
phosphatase and actin regulator 2
chr2_+_203706614 0.42 ENST00000324106.9
CD28
CD28 molecule
chr4_-_41748713 0.40 ENST00000226382.4
PHOX2B
paired like homeobox 2B
chr16_+_67846917 0.39 ENST00000219169.9
ENST00000567105.5
NUTF2
nuclear transport factor 2
chr7_-_139777986 0.37 ENST00000406875.8
HIPK2
homeodomain interacting protein kinase 2
chr11_+_125626229 0.37 ENST00000532449.6
ENST00000534070.5
CHEK1
checkpoint kinase 1
chr11_+_67391975 0.36 ENST00000307980.7
RAD9A
RAD9 checkpoint clamp component A
chr17_-_5584448 0.35 ENST00000269280.8
ENST00000571451.6
ENST00000572272.6
ENST00000613500.4
ENST00000619223.4
ENST00000617618.4
ENST00000345221.7
ENST00000262467.10
NLRP1
NLR family pyrin domain containing 1
chr22_-_41621014 0.34 ENST00000263256.7
DESI1
desumoylating isopeptidase 1
chr2_+_203014842 0.34 ENST00000683969.1
ENST00000449802.5
NBEAL1
neurobeachin like 1
chr3_-_129688691 0.33 ENST00000432054.6
TMCC1
transmembrane and coiled-coil domain family 1
chr1_+_65147514 0.33 ENST00000545314.5
AK4
adenylate kinase 4
chr1_+_26826682 0.33 ENST00000374142.9
ZDHHC18
zinc finger DHHC-type palmitoyltransferase 18
chr1_-_22143088 0.32 ENST00000290167.11
WNT4
Wnt family member 4
chr5_+_73498408 0.30 ENST00000335895.12
ENST00000678135.1
ENST00000380591.7
ENST00000677654.1
ENST00000507081.6
BTF3
basic transcription factor 3
chr8_+_94641145 0.29 ENST00000433389.8
ENST00000358397.9
ESRP1
epithelial splicing regulatory protein 1
chr4_+_71339014 0.29 ENST00000340595.4
SLC4A4
solute carrier family 4 member 4
chr2_+_46698909 0.29 ENST00000650611.1
ENST00000306503.5
LINC01118
SOCS5
long intergenic non-protein coding RNA 1118
suppressor of cytokine signaling 5
chr12_-_57006476 0.27 ENST00000300101.3
ZBTB39
zinc finger and BTB domain containing 39
chr5_+_131264043 0.27 ENST00000505065.2
ENST00000503291.5
ENST00000360515.7
CDC42SE2
CDC42 small effector 2
chr8_-_42541898 0.23 ENST00000342228.7
SLC20A2
solute carrier family 20 member 2
chr13_-_46387447 0.22 ENST00000676051.1
ENST00000378787.7
ENST00000378781.7
ENST00000378797.6
RUBCNL
rubicon like autophagy enhancer
chr5_-_133612524 0.21 ENST00000265342.12
FSTL4
follistatin like 4
chr1_+_15526813 0.19 ENST00000375838.5
ENST00000616884.4
ENST00000375849.5
ENST00000375847.8
DNAJC16
DnaJ heat shock protein family (Hsp40) member C16
chr16_-_30787169 0.18 ENST00000262525.6
ZNF629
zinc finger protein 629
chr1_+_203795614 0.18 ENST00000367210.3
ENST00000432282.5
ENST00000453771.5
ENST00000367214.5
ENST00000639812.1
ENST00000367212.7
ENST00000332127.8
ENST00000550078.2
ZC3H11A
ZBED6
zinc finger CCCH-type containing 11A
zinc finger BED-type containing 6
chr11_-_119381629 0.17 ENST00000260187.7
ENST00000455332.6
USP2
ubiquitin specific peptidase 2
chr6_+_43076262 0.15 ENST00000476760.1
ENST00000230419.9
ENST00000471863.5
ENST00000345201.6
ENST00000349241.6
ENST00000352931.6
PTK7
protein tyrosine kinase 7 (inactive)
chr17_+_4997901 0.11 ENST00000320785.10
ENST00000574165.1
KIF1C
kinesin family member 1C
chr5_+_157743703 0.11 ENST00000286307.6
LSM11
LSM11, U7 small nuclear RNA associated
chr1_+_35931076 0.09 ENST00000397828.3
ENST00000373191.9
AGO3
argonaute RISC catalytic component 3
chr3_+_42160160 0.06 ENST00000341421.7
ENST00000396175.5
TRAK1
trafficking kinesin protein 1
chr1_-_23980308 0.01 ENST00000374452.9
ENST00000492112.3
ENST00000343255.9
ENST00000344989.10
SRSF10
serine and arginine rich splicing factor 10

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.6 1.9 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.6 1.9 GO:0048073 regulation of eye pigmentation(GO:0048073)
0.5 1.4 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.4 1.5 GO:0032848 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.3 1.0 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.3 1.2 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.3 0.9 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.3 2.6 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.3 1.7 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.3 1.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3 0.8 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.2 0.5 GO:0098528 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.2 2.2 GO:0002934 desmosome organization(GO:0002934) enamel mineralization(GO:0070166)
0.2 1.5 GO:0000255 allantoin metabolic process(GO:0000255)
0.2 2.1 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 1.6 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.2 0.6 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.2 1.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.2 0.7 GO:0003175 tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
0.2 1.6 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.2 0.9 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2 1.9 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.2 2.8 GO:0006020 inositol metabolic process(GO:0006020)
0.2 3.5 GO:0071481 cellular response to X-ray(GO:0071481)
0.2 0.6 GO:2000317 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.2 0.6 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.1 0.4 GO:0003358 noradrenergic neuron development(GO:0003358)
0.1 0.8 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.9 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 0.9 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.1 2.1 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.3 GO:0061054 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) positive regulation of dermatome development(GO:0061184) positive regulation of steroid hormone biosynthetic process(GO:0090031) regulation of testosterone biosynthetic process(GO:2000224)
0.1 1.5 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 2.0 GO:0032354 response to follicle-stimulating hormone(GO:0032354)
0.1 1.3 GO:0015074 DNA integration(GO:0015074)
0.1 0.4 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.1 1.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.8 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.6 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 0.6 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 1.1 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 1.7 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 0.8 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 1.3 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.4 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.1 1.7 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.6 GO:0071211 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734) protein targeting to vacuole involved in autophagy(GO:0071211)
0.1 0.2 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.1 1.0 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.1 0.8 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
0.1 0.4 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1 1.3 GO:0035428 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.0 0.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.4 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.6 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.5 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.7 GO:0002070 epithelial cell maturation(GO:0002070)
0.0 1.8 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.7 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 2.9 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.4 GO:0002863 positive regulation of inflammatory response to antigenic stimulus(GO:0002863)
0.0 2.2 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.7 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.7 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 1.6 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.2 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 1.1 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.7 GO:0015012 heparan sulfate proteoglycan biosynthetic process(GO:0015012)
0.0 0.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 1.3 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.3 GO:0046033 AMP metabolic process(GO:0046033)
0.0 0.3 GO:0032495 response to muramyl dipeptide(GO:0032495)
0.0 0.1 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 1.7 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.1 GO:0090625 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.6 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.5 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.5 1.5 GO:0070195 growth hormone receptor complex(GO:0070195)
0.4 2.2 GO:0032584 growth cone membrane(GO:0032584)
0.3 1.6 GO:0044305 calyx of Held(GO:0044305)
0.1 1.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 1.0 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.9 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 1.3 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.1 0.3 GO:0072558 NLRP1 inflammasome complex(GO:0072558)
0.1 1.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 1.5 GO:0046930 pore complex(GO:0046930)
0.1 2.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.7 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 2.6 GO:0001772 immunological synapse(GO:0001772)
0.0 5.5 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.6 GO:0016342 catenin complex(GO:0016342)
0.0 1.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.7 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 2.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.1 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.0 1.7 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.0 1.4 GO:0005796 Golgi lumen(GO:0005796)
0.0 2.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.4 0.7 GO:0098821 BMP receptor activity(GO:0098821)
0.3 2.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 0.9 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.3 0.8 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.2 3.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.2 1.4 GO:0043237 laminin-1 binding(GO:0043237)
0.2 0.7 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.2 2.5 GO:0046790 virion binding(GO:0046790)
0.2 0.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 1.9 GO:0017002 activin-activated receptor activity(GO:0017002)
0.2 1.9 GO:0005113 patched binding(GO:0005113)
0.2 0.6 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 1.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.9 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.7 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 0.8 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 1.5 GO:0051434 BH3 domain binding(GO:0051434)
0.1 1.3 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 2.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.3 GO:0048185 activin binding(GO:0048185)
0.1 0.5 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.7 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.1 0.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.1 0.5 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.1 1.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 0.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 2.0 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.4 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 1.4 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 0.2 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 1.1 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.8 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 1.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.8 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 1.4 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 1.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 1.1 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 3.2 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 2.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 2.1 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 1.0 GO:0019894 kinesin binding(GO:0019894)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 2.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.0 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 1.1 GO:0008013 beta-catenin binding(GO:0008013)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 1.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 2.5 PID ALK1 PATHWAY ALK1 signaling events
0.1 1.9 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 2.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 2.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 1.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.3 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 2.0 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 2.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.7 PID P53 REGULATION PATHWAY p53 pathway
0.0 1.1 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.3 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID ATM PATHWAY ATM pathway
0.0 0.5 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 3.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.1 4.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.0 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 2.1 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 2.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 2.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.1 1.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 3.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 0.7 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 2.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 2.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.4 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 3.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.7 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.9 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.3 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.4 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress