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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for AGGUAGU

Z-value: 0.39

Motif logo

miRNA associated with seed AGGUAGU

NamemiRBASE accession
MIMAT0000226
MIMAT0001080

Activity profile of AGGUAGU motif

Sorted Z-values of AGGUAGU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AGGUAGU

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_+_94394886 4.42 ENST00000297268.11
ENST00000620463.1
collagen type I alpha 2 chain
chr1_-_204411804 4.18 ENST00000367188.5
protein phosphatase 1 regulatory subunit 15B
chr9_+_122264857 3.82 ENST00000344641.8
ENST00000441707.5
ENST00000373723.9
ENST00000373729.5
mitochondrial ribosome recycling factor
chr5_-_131796921 3.64 ENST00000307968.11
ENST00000307954.12
folliculin interacting protein 1
chr12_+_65824475 3.36 ENST00000403681.7
high mobility group AT-hook 2
chr17_-_48604959 2.98 ENST00000225648.4
ENST00000484302.3
homeobox B6
chr5_-_37371061 2.85 ENST00000513532.1
ENST00000231498.8
nucleoporin 155
chr6_+_34236865 2.64 ENST00000674029.1
ENST00000447654.5
ENST00000347617.10
ENST00000401473.7
ENST00000311487.9
high mobility group AT-hook 1
chr2_+_188974364 2.63 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr2_+_241702027 2.62 ENST00000313552.11
ENST00000406941.5
inhibitor of growth family member 5
chr6_+_133953210 2.40 ENST00000367869.1
ENST00000237264.9
ENST00000674115.1
TATA-box binding protein like 1
novel protein
chr7_-_23470469 2.39 ENST00000258729.8
insulin like growth factor 2 mRNA binding protein 3
chr3_-_53046031 2.31 ENST00000482396.5
ENST00000394752.8
Scm like with four mbt domains 1
chr4_+_112145445 2.25 ENST00000309733.6
family with sequence similarity 241 member A
chr17_-_48610971 2.09 ENST00000239165.9
homeobox B7
chr9_-_16870662 2.09 ENST00000380672.9
basonuclin 2
chr1_-_114716729 1.91 ENST00000369535.5
NRAS proto-oncogene, GTPase
chr3_-_28348805 1.90 ENST00000457172.5
ENST00000479665.6
5-azacytidine induced 2
chr17_+_18315273 1.83 ENST00000406438.5
SMCR8-C9orf72 complex subunit
chr2_+_203328378 1.78 ENST00000430418.5
ENST00000261018.12
ENST00000295851.10
ENST00000424558.5
ENST00000417864.5
ENST00000422511.6
abl interactor 2
chr3_+_61561561 1.67 ENST00000474889.6
protein tyrosine phosphatase receptor type G
chr15_+_45587366 1.55 ENST00000220531.9
biogenesis of lysosomal organelles complex 1 subunit 6
chr17_-_50201618 1.54 ENST00000225964.10
collagen type I alpha 1 chain
chrX_+_96684801 1.46 ENST00000324765.13
diaphanous related formin 2
chr1_+_59814939 1.41 ENST00000371208.5
hook microtubule tethering protein 1
chr2_+_108719473 1.35 ENST00000283195.11
RAN binding protein 2
chr3_+_14947568 1.35 ENST00000413118.5
ENST00000425241.5
nuclear receptor subfamily 2 group C member 2
chr20_+_325536 1.33 ENST00000342665.5
SRY-box transcription factor 12
chr18_+_22169580 1.30 ENST00000269216.10
GATA binding protein 6
chr9_+_113221528 1.29 ENST00000374212.5
solute carrier family 31 member 1
chrX_-_133415478 1.24 ENST00000370828.4
glypican 4
chr18_+_6834473 1.20 ENST00000581099.5
ENST00000419673.6
ENST00000531294.5
Rho GTPase activating protein 28
chr10_+_96043394 1.16 ENST00000403870.7
ENST00000265992.9
ENST00000465148.3
cyclin J
chr2_-_39437264 1.12 ENST00000263881.8
ENST00000341681.9
mitogen-activated protein kinase kinase kinase kinase 3
chr14_-_57268810 1.11 ENST00000413566.6
ENST00000340918.11
ENST00000621441.5
exocyst complex component 5
chr1_+_193121950 1.09 ENST00000367435.5
cell division cycle 73
chr8_-_81842192 1.08 ENST00000353788.8
ENST00000520618.5
ENST00000518183.5
ENST00000396330.6
ENST00000519119.5
sorting nexin 16
chr20_+_50731571 1.07 ENST00000371610.7
par-6 family cell polarity regulator beta
chr12_-_24949026 1.02 ENST00000539780.5
ENST00000546285.1
ENST00000342945.9
ENST00000261192.12
branched chain amino acid transaminase 1
chr1_-_207051202 0.97 ENST00000315927.9
YOD1 deubiquitinase
chr16_+_22206255 0.95 ENST00000263026.10
eukaryotic elongation factor 2 kinase
chr12_-_57006476 0.94 ENST00000300101.3
zinc finger and BTB domain containing 39
chr12_-_92929236 0.94 ENST00000322349.13
early endosome antigen 1
chr9_-_124771304 0.88 ENST00000416460.6
ENST00000487099.7
nuclear receptor subfamily 6 group A member 1
chr12_-_68933161 0.84 ENST00000549781.1
ENST00000551568.6
ENST00000548262.5
carboxypeptidase M
chr8_+_22245125 0.82 ENST00000306433.9
ENST00000519237.5
ENST00000397802.8
RNA polymerase III subunit D
chr9_+_96450115 0.81 ENST00000375249.5
ENST00000375251.7
hyaluronan binding protein 4
chr4_+_55346213 0.80 ENST00000679836.1
ENST00000264228.9
ENST00000679707.1
steroid 5 alpha-reductase 3
novel protein, SRD5A3-RP11-177J6.1 readthrough
chr1_+_113073162 0.80 ENST00000361127.6
leucine rich repeats and immunoglobulin like domains 2
chr5_+_38846002 0.80 ENST00000274276.8
oncostatin M receptor
chrX_-_41922992 0.80 ENST00000646120.2
ENST00000421587.8
ENST00000644770.1
ENST00000645566.1
ENST00000378166.9
ENST00000378158.6
ENST00000644219.1
ENST00000442742.7
ENST00000644347.1
calcium/calmodulin dependent serine protein kinase
chr3_-_48188356 0.77 ENST00000351231.7
ENST00000437972.1
ENST00000302506.8
cell division cycle 25A
chr7_-_27143672 0.77 ENST00000222726.4
homeobox A5
chr21_+_29298890 0.75 ENST00000286800.8
BTB domain and CNC homolog 1
chr1_+_18630839 0.75 ENST00000420770.7
paired box 7
chr2_-_127858107 0.74 ENST00000409955.1
ENST00000272645.9
RNA polymerase II subunit D
chr11_+_112074287 0.72 ENST00000532163.5
ENST00000280352.13
ENST00000393047.8
ENST00000526879.5
ENST00000525785.5
NKAP domain containing 1
chr7_+_94656325 0.71 ENST00000482108.1
ENST00000488574.5
ENST00000612748.1
ENST00000613043.1
paternally expressed 10
chr12_+_54008961 0.71 ENST00000040584.6
homeobox C8
chr2_+_5692357 0.70 ENST00000322002.5
SRY-box transcription factor 11
chr7_-_27156646 0.62 ENST00000242159.5
homeobox A7
chr1_+_26410809 0.61 ENST00000254231.4
ENST00000326279.11
lin-28 homolog A
chr10_+_96832252 0.60 ENST00000676187.1
ENST00000675687.1
ENST00000676123.1
ENST00000675471.1
ENST00000371103.8
ENST00000421806.4
ENST00000675250.1
ENST00000540664.6
ENST00000676414.1
ligand dependent nuclear receptor corepressor
chr2_+_169733811 0.60 ENST00000392647.7
kelch like family member 23
chrX_-_135052114 0.59 ENST00000370775.3
retrotransposon Gag like 8A
chr19_+_13952466 0.59 ENST00000254337.10
DDB1 and CUL4 associated factor 15
chr19_+_531750 0.58 ENST00000215574.9
cell division cycle 34, ubiqiutin conjugating enzyme
chr19_-_47471886 0.57 ENST00000236877.11
ENST00000597014.1
solute carrier family 8 member A2
chr22_+_39502237 0.57 ENST00000325301.7
mitochondrial elongation factor 1
chr3_-_21751189 0.56 ENST00000281523.8
zinc finger protein 385D
chr1_+_164559766 0.56 ENST00000367897.5
ENST00000559240.5
PBX homeobox 1
chr12_+_50400809 0.54 ENST00000293618.12
ENST00000429001.7
ENST00000398473.7
ENST00000548174.5
ENST00000548697.5
ENST00000548993.5
ENST00000614335.4
ENST00000522085.5
ENST00000615080.4
ENST00000518444.5
ENST00000551886.5
ENST00000523389.5
ENST00000518561.5
ENST00000347328.9
ENST00000550260.1
La ribonucleoprotein 4
chr16_+_70299156 0.53 ENST00000393657.6
ENST00000288071.11
ENST00000355992.7
ENST00000567706.1
ENST00000443119.7
DEAD-box helicase 19B
novel protein, DDX19B and DDX19A readthrough
chr15_+_51751587 0.51 ENST00000539962.6
ENST00000249700.9
tropomodulin 2
chr16_-_67806513 0.51 ENST00000317506.8
ENST00000448631.6
ENST00000602677.5
ENST00000630626.2
RAN binding protein 10
chr7_+_18495723 0.50 ENST00000681950.1
ENST00000622668.4
ENST00000405010.7
ENST00000406451.8
ENST00000441542.7
ENST00000428307.6
ENST00000681273.1
histone deacetylase 9
chr9_+_130172343 0.49 ENST00000372398.6
neuronal calcium sensor 1
chr7_+_77696423 0.49 ENST00000334955.13
round spermatid basic protein 1 like
chr7_-_27165517 0.48 ENST00000396345.1
ENST00000343483.7
homeobox A9
chr7_-_84194781 0.48 ENST00000265362.9
semaphorin 3A
chr3_+_159839847 0.47 ENST00000445224.6
schwannomin interacting protein 1
chr8_-_67343768 0.47 ENST00000262215.8
ADP ribosylation factor guanine nucleotide exchange factor 1
chr14_-_81220951 0.46 ENST00000553612.6
general transcription factor IIA subunit 1
chr1_+_153259684 0.45 ENST00000368742.4
loricrin cornified envelope precursor protein
chr7_-_99144053 0.45 ENST00000361125.1
ENST00000361368.7
SMAD specific E3 ubiquitin protein ligase 1
chr7_-_120858066 0.44 ENST00000222747.8
tetraspanin 12
chr1_-_205631962 0.44 ENST00000289703.8
ENST00000357992.9
ETS transcription factor ELK4
chr17_+_8310220 0.40 ENST00000583529.1
ENST00000361926.8
Rho guanine nucleotide exchange factor 15
chr3_-_47781837 0.39 ENST00000254480.10
SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1
chr8_-_109975757 0.37 ENST00000524391.6
potassium voltage-gated channel modifier subfamily V member 1
chr12_-_29381141 0.36 ENST00000546839.5
ENST00000552155.5
ENST00000360150.9
ENST00000550353.5
ENST00000548441.1
ENST00000552132.5
ERGIC and golgi 2
chr12_+_123384078 0.35 ENST00000402868.8
lysine methyltransferase 5A
chr4_+_17614630 0.34 ENST00000237380.12
mediator complex subunit 28
chr6_-_85642922 0.33 ENST00000616122.5
ENST00000678618.1
ENST00000678816.1
ENST00000676630.1
ENST00000678589.1
ENST00000678878.1
ENST00000676542.1
ENST00000355238.11
ENST00000678899.1
synaptotagmin binding cytoplasmic RNA interacting protein
chr8_+_80485641 0.31 ENST00000430430.5
zinc finger and BTB domain containing 10
chrX_+_68499021 0.31 ENST00000462683.6
Yip1 domain family member 6
chr15_+_66702219 0.30 ENST00000288840.10
SMAD family member 6
chr4_-_18021727 0.29 ENST00000675605.1
ENST00000675927.1
ENST00000674942.1
ENST00000675143.1
ENST00000382226.5
ENST00000326877.8
ENST00000635767.1
ligand dependent nuclear receptor corepressor like
chr5_+_178859924 0.28 ENST00000322434.8
zinc finger protein 354B
chr6_+_4889992 0.26 ENST00000343762.5
chromodomain Y like
chr18_+_23453275 0.25 ENST00000581585.5
ENST00000339486.8
ENST00000577501.5
RIO kinase 3
chr12_-_122966438 0.23 ENST00000344275.11
ENST00000442833.6
ENST00000280560.13
ENST00000540285.5
ENST00000346530.9
ATP binding cassette subfamily B member 9
chr15_-_50119215 0.23 ENST00000284509.11
ENST00000674213.1
ATPase phospholipid transporting 8B4 (putative)
chr6_+_24402908 0.20 ENST00000274747.11
ENST00000443868.6
ENST00000378386.8
ENST00000378353.5
magnesium transporter MRS2
chr22_+_50343294 0.20 ENST00000359139.7
ENST00000395741.7
ENST00000612753.5
ENST00000395744.7
protein phosphatase 6 regulatory subunit 2
chr18_-_76495191 0.20 ENST00000443185.7
zinc finger protein 516
chr12_-_57078739 0.19 ENST00000379391.7
nuclear envelope integral membrane protein 1
chr8_+_57994455 0.18 ENST00000361488.7
family with sequence similarity 110 member B
chr9_-_69672341 0.17 ENST00000265381.7
amyloid beta precursor protein binding family A member 1
chr20_-_34112205 0.17 ENST00000374980.3
eukaryotic translation initiation factor 2 subunit beta
chr10_-_37857582 0.17 ENST00000395867.8
ENST00000611278.4
zinc finger protein 248
chr9_-_76906090 0.16 ENST00000376718.8
prune homolog 2 with BCH domain
chr8_+_120125093 0.16 ENST00000297848.8
ENST00000309791.8
collagen type XIV alpha 1 chain
chr7_-_75738930 0.16 ENST00000336926.11
ENST00000434438.6
huntingtin interacting protein 1
chr6_-_93419545 0.15 ENST00000369297.1
ENST00000369303.9
ENST00000680224.1
ENST00000681532.1
ENST00000679565.1
EPH receptor A7
chr15_-_34210073 0.15 ENST00000559515.1
ENST00000560108.5
ENST00000256544.8
ENST00000559462.1
katanin regulatory subunit B1 like 1
chr1_-_179229671 0.15 ENST00000502732.6
ENST00000392043.4
ABL proto-oncogene 2, non-receptor tyrosine kinase
chrX_+_2828808 0.15 ENST00000381163.7
glycogenin 2
chr5_+_154445979 0.14 ENST00000297109.11
SAP30 like
chr17_+_32444379 0.14 ENST00000578213.5
ENST00000649012.1
ENST00000457654.6
ENST00000579451.1
ENST00000261712.8
proteasome 26S subunit, non-ATPase 11
chr11_-_796185 0.14 ENST00000533385.5
ENST00000528936.5
ENST00000629634.2
ENST00000625752.2
ENST00000528606.5
ENST00000320230.9
solute carrier family 25 member 22
chr7_+_35800932 0.13 ENST00000635172.1
ENST00000399034.7
ENST00000350320.10
ENST00000435235.6
ENST00000672279.1
ENST00000634600.1
ENST00000635047.1
septin 7
chrX_+_49922605 0.12 ENST00000376088.7
chloride voltage-gated channel 5
chrX_+_118974608 0.11 ENST00000304778.11
ENST00000371628.8
LON peptidase N-terminal domain and ring finger 3
chr11_-_78188588 0.11 ENST00000526208.5
ENST00000529350.1
ENST00000530018.5
ENST00000528776.1
ENST00000340067.4
potassium channel tetramerization domain containing 21
chr5_+_56815534 0.11 ENST00000399503.4
mitogen-activated protein kinase kinase kinase 1
chr12_+_62260338 0.11 ENST00000353364.7
ENST00000549523.5
ubiquitin specific peptidase 15
chr2_+_112482133 0.10 ENST00000233336.7
tubulin tyrosine ligase
chr9_+_107283256 0.10 ENST00000358015.8
RAD23 homolog B, nucleotide excision repair protein
chr1_+_4654601 0.09 ENST00000378191.5
adherens junctions associated protein 1
chr10_+_100912955 0.09 ENST00000370271.7
ENST00000238961.9
ENST00000370269.3
ENST00000609386.1
SMC5-SMC6 complex localization factor 2
chr22_-_21867610 0.09 ENST00000215832.11
ENST00000398822.7
mitogen-activated protein kinase 1
chr5_-_154478218 0.07 ENST00000231121.3
heart and neural crest derivatives expressed 1
chr3_+_133574434 0.06 ENST00000508481.5
ENST00000420115.6
ENST00000504867.5
ENST00000507408.5
ENST00000511392.5
ENST00000515421.1
CDV3 homolog
chr16_+_29778252 0.06 ENST00000400752.6
zymogen granule protein 16
chr16_-_11915878 0.06 ENST00000439887.6
ENST00000434724.7
G1 to S phase transition 1
chr17_-_63773534 0.05 ENST00000403162.7
ENST00000582252.1
ENST00000225726.10
coiled-coil domain containing 47
chr18_-_21111778 0.04 ENST00000399799.3
Rho associated coiled-coil containing protein kinase 1
chr13_-_102401599 0.03 ENST00000376131.8
fibroblast growth factor 14
chr17_+_30378903 0.03 ENST00000225719.9
carboxypeptidase D
chr22_+_29883158 0.03 ENST00000333027.7
ENST00000401950.7
ENST00000445401.5
ENST00000323630.9
ENST00000351488.7
myotubularin related protein 3
chr2_+_159712457 0.02 ENST00000539065.5
ENST00000259050.8
ENST00000409175.6
ENST00000421037.1
membrane associated ring-CH-type finger 7
chr16_+_397183 0.02 ENST00000620944.4
ENST00000621774.4
ENST00000219479.7
NME/NM23 nucleoside diphosphate kinase 4
chr2_-_50347710 0.01 ENST00000342183.9
ENST00000401710.5
neurexin 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.0 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.7 3.6 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.6 1.9 GO:0044565 dendritic cell proliferation(GO:0044565)
0.6 1.8 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.5 4.2 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898) negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.4 2.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.4 1.3 GO:0032912 negative regulation of transforming growth factor beta2 production(GO:0032912)
0.4 6.0 GO:0043589 skin morphogenesis(GO:0043589)
0.4 3.8 GO:0032790 ribosome disassembly(GO:0032790)
0.4 2.4 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.3 1.7 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.3 1.0 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.3 1.8 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.3 0.8 GO:0060435 bronchiole development(GO:0060435)
0.2 0.7 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
0.2 2.9 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.2 0.9 GO:1990637 response to prolactin(GO:1990637)
0.2 0.7 GO:0061386 closure of optic fissure(GO:0061386)
0.2 1.4 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.2 1.0 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2 0.6 GO:0010587 miRNA catabolic process(GO:0010587)
0.2 0.8 GO:0016095 polyprenol catabolic process(GO:0016095)
0.2 1.8 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 1.3 GO:0072719 copper ion import(GO:0015677) cellular response to cisplatin(GO:0072719)
0.2 0.8 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 0.5 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.1 1.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 1.5 GO:0016081 synaptic vesicle docking(GO:0016081)
0.1 0.4 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.1 0.5 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) sensory system development(GO:0048880) facioacoustic ganglion development(GO:1903375)
0.1 0.8 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1 0.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 2.1 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 0.6 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 3.5 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.1 2.1 GO:0043586 tongue development(GO:0043586)
0.1 0.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.3 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.6 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.4 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.5 GO:0042118 endothelial cell activation(GO:0042118)
0.1 1.9 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.8 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 1.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 1.3 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.3 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.3 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 2.3 GO:0048635 negative regulation of muscle organ development(GO:0048635)
0.0 0.2 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.2 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.0 0.1 GO:0030860 regulation of polarized epithelial cell differentiation(GO:0030860)
0.0 0.1 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.0 2.6 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.4 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.2 GO:0002176 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.0 0.2 GO:0072178 nephric duct morphogenesis(GO:0072178)
0.0 0.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 2.4 GO:0042035 regulation of cytokine biosynthetic process(GO:0042035)
0.0 2.7 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 0.3 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.6 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.8 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.0 0.8 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 1.1 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.0 0.2 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.4 GO:0010842 retina layer formation(GO:0010842)
0.0 1.5 GO:0048477 oogenesis(GO:0048477)
0.0 1.2 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.0 1.1 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.9 GO:0021510 spinal cord development(GO:0021510)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0044611 nuclear pore inner ring(GO:0044611)
0.9 6.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.7 8.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.5 1.4 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.4 1.4 GO:0070695 FHF complex(GO:0070695)
0.3 2.9 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.3 1.8 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.2 4.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.2 2.6 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.2 1.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 1.8 GO:0031209 SCAR complex(GO:0031209)
0.1 1.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 1.1 GO:0000145 exocyst(GO:0000145)
0.0 0.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.8 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.3 GO:0097452 GAIT complex(GO:0097452)
0.0 0.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.4 GO:0001741 XY body(GO:0001741)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.2 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.1 GO:0018444 translation release factor complex(GO:0018444)
0.0 2.1 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.1 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 1.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.8 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.6 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.7 3.4 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.7 8.6 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.6 3.8 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.3 1.0 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.3 0.8 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.2 1.0 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 2.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 0.8 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.2 1.2 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 1.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.1 2.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.6 GO:0045499 chemorepellent activity(GO:0045499)
0.1 0.8 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.4 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 1.1 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 2.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 1.7 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 1.8 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.8 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.9 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.8 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.5 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.9 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 1.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.1 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 2.0 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.7 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.9 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 2.2 GO:0003707 steroid hormone receptor activity(GO:0003707)
0.0 1.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 2.3 GO:0042393 histone binding(GO:0042393)
0.0 0.7 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 5.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 1.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 1.1 GO:0019905 syntaxin binding(GO:0019905)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 8.8 NABA COLLAGENS Genes encoding collagen proteins
0.1 2.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 1.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 0.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 4.6 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.3 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.1 PID INSULIN PATHWAY Insulin Pathway
0.0 1.1 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 PID BMP PATHWAY BMP receptor signaling
0.0 0.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.2 2.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 2.0 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.1 4.2 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 0.8 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 0.7 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.1 0.8 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 0.9 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 1.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 1.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.2 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 2.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.6 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.5 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening