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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ARID5B

Z-value: 0.38

Motif logo

Transcription factors associated with ARID5B

Gene Symbol Gene ID Gene Info
ENSG00000150347.17 ARID5B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ARID5Bhg38_v1_chr10_+_61901678_619017060.195.1e-03Click!

Activity profile of ARID5B motif

Sorted Z-values of ARID5B motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ARID5B

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_-_98522869 7.61 ENST00000502288.5
ENST00000512147.5
ENST00000341181.11
ENST00000510541.5
ENST00000503621.5
ENST00000511081.5
ENST00000507874.5
ENST00000502299.5
ENST00000508659.5
ENST00000510545.5
ENST00000511667.5
ENST00000394185.6
claudin domain containing 1
chr3_-_98522514 7.34 ENST00000503004.5
ENST00000506575.1
ENST00000513452.5
ENST00000515620.5
claudin domain containing 1
chr11_-_111923722 6.81 ENST00000527950.5
crystallin alpha B
chr12_+_78863962 5.61 ENST00000393240.7
synaptotagmin 1
chr12_+_78864768 5.26 ENST00000261205.9
ENST00000457153.6
synaptotagmin 1
chr4_+_87975829 3.83 ENST00000614857.5
secreted phosphoprotein 1
chr1_+_84181630 3.43 ENST00000610457.1
protein kinase cAMP-activated catalytic subunit beta
chr3_-_79767987 3.36 ENST00000464233.6
roundabout guidance receptor 1
chr4_+_76074701 3.13 ENST00000355810.9
ENST00000349321.7
ADP-ribosyltransferase 3 (inactive)
chr12_-_91146195 3.01 ENST00000548218.1
decorin
chr22_-_21735744 2.93 ENST00000403503.1
yippee like 1
chr15_+_24823625 2.92 ENST00000400100.5
ENST00000645002.1
ENST00000642807.1
small nuclear ribonucleoprotein polypeptide N
chr7_-_24757926 2.69 ENST00000342947.9
ENST00000419307.6
gasdermin E
chr2_+_222861005 2.67 ENST00000680147.1
ENST00000681009.1
ENST00000679514.1
ENST00000357430.8
acyl-CoA synthetase long chain family member 3
chr22_-_21735776 2.65 ENST00000339468.8
yippee like 1
chr18_-_28036585 2.62 ENST00000399380.7
cadherin 2
chr2_+_222860942 2.54 ENST00000392066.7
ENST00000680251.1
ENST00000679541.1
ENST00000679545.1
ENST00000680395.1
acyl-CoA synthetase long chain family member 3
chr17_+_3475959 2.46 ENST00000263080.3
aspartoacylase
chr2_+_222861059 2.44 ENST00000681697.1
ENST00000680921.1
acyl-CoA synthetase long chain family member 3
chr2_+_227325225 2.44 ENST00000353339.7
mitochondrial fission factor
chr5_+_161850597 2.39 ENST00000634335.1
ENST00000635880.1
gamma-aminobutyric acid type A receptor subunit alpha1
chr4_-_86101922 2.29 ENST00000472236.5
ENST00000641881.1
mitogen-activated protein kinase 10
chr10_+_124461800 2.25 ENST00000368842.10
ENST00000392757.8
ENST00000368839.1
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chr7_+_154052373 2.20 ENST00000377770.8
ENST00000406326.5
dipeptidyl peptidase like 6
chr18_+_34976928 2.16 ENST00000591734.5
ENST00000413393.5
ENST00000589180.5
ENST00000587359.5
microtubule associated protein RP/EB family member 2
chr16_-_3372666 1.99 ENST00000399974.5
MT-RNR2 like 4
chr1_+_151766655 1.92 ENST00000400999.7
ornithine decarboxylase antizyme 3
chr17_-_10549694 1.88 ENST00000622564.4
myosin heavy chain 2
chr2_-_2324642 1.82 ENST00000650485.1
ENST00000649207.1
myelin transcription factor 1 like
chr12_-_8662703 1.70 ENST00000535336.5
microfibril associated protein 5
chr5_-_88883701 1.69 ENST00000636998.1
myocyte enhancer factor 2C
chr2_-_74392025 1.68 ENST00000440727.1
ENST00000409240.5
dynactin subunit 1
chr13_+_51861963 1.62 ENST00000242819.7
coiled-coil domain containing 70
chr12_-_8662619 1.59 ENST00000544889.1
ENST00000543369.5
microfibril associated protein 5
chr18_-_55635948 1.56 ENST00000565124.4
ENST00000398339.5
transcription factor 4
chr17_-_68955332 1.55 ENST00000269080.6
ENST00000615593.4
ENST00000586539.6
ENST00000430352.6
ATP binding cassette subfamily A member 8
chr12_-_119803383 1.49 ENST00000392520.2
ENST00000678677.1
ENST00000679249.1
ENST00000676849.1
citron rho-interacting serine/threonine kinase
chr12_-_8662073 1.48 ENST00000535411.5
ENST00000540087.5
microfibril associated protein 5
chr4_+_105710809 1.48 ENST00000360505.9
ENST00000510865.5
ENST00000509336.5
glutathione S-transferase C-terminal domain containing
chr19_+_17215332 1.47 ENST00000263897.10
unconventional SNARE in the ER 1
chr9_+_111525148 1.43 ENST00000358151.8
ENST00000309235.6
ENST00000355824.7
ENST00000374374.3
zinc finger protein 483
chr11_-_95910665 1.36 ENST00000674610.1
ENST00000675660.1
myotubularin related protein 2
chrX_-_141242512 1.35 ENST00000358993.3
SPANX family member C
chr17_-_10549612 1.33 ENST00000532183.6
ENST00000397183.6
ENST00000420805.1
myosin heavy chain 2
chr17_+_55266216 1.31 ENST00000573945.5
HLF transcription factor, PAR bZIP family member
chr6_-_119149124 1.30 ENST00000368475.8
family with sequence similarity 184 member A
chr1_-_75611083 1.27 ENST00000370855.5
solute carrier family 44 member 5
chr1_+_75724431 1.26 ENST00000541113.6
ENST00000680805.1
acyl-CoA dehydrogenase medium chain
chr16_+_58392462 1.25 ENST00000318129.6
GINS complex subunit 3
chr2_+_69013379 1.17 ENST00000409349.7
ANTXR cell adhesion molecule 1
chr1_-_168137430 1.14 ENST00000546300.5
ENST00000271357.9
ENST00000367835.1
ENST00000537209.5
G protein-coupled receptor 161
chr11_-_33753394 1.13 ENST00000532057.5
ENST00000531080.5
F-box protein 3
chr1_+_77779763 1.13 ENST00000646892.1
ENST00000645526.1
mitoguardin 1
chr10_-_73591330 1.11 ENST00000451492.5
ENST00000681793.1
ENST00000680396.1
ENST00000413442.5
ubiquitin specific peptidase 54
chr17_-_10549652 1.09 ENST00000245503.10
myosin heavy chain 2
chr20_+_36091409 1.09 ENST00000202028.9
erythrocyte membrane protein band 4.1 like 1
chr2_+_69013414 1.03 ENST00000681816.1
ENST00000482235.2
ANTXR cell adhesion molecule 1
chr7_-_105269007 1.02 ENST00000357311.7
SRSF protein kinase 2
chr20_-_9839026 1.01 ENST00000378429.3
ENST00000353224.10
p21 (RAC1) activated kinase 5
chr16_+_58392391 0.97 ENST00000426538.6
ENST00000328514.11
GINS complex subunit 3
chr5_+_132658165 0.97 ENST00000617259.2
ENST00000304506.7
interleukin 13
chr5_+_137889469 0.97 ENST00000290431.5
polycystin 2 like 2, transient receptor potential cation channel
chr13_-_41132728 0.96 ENST00000379485.2
kelch repeat and BTB domain containing 6
chr5_+_155013755 0.93 ENST00000435029.6
kinesin family member 4B
chr12_+_120496075 0.92 ENST00000548214.1
ENST00000392508.2
dynein light chain LC8-type 1
chr14_+_73097027 0.92 ENST00000532192.1
RNA binding motif protein 25
chr1_+_43389889 0.92 ENST00000562955.2
ENST00000634258.3
SZT2 subunit of KICSTOR complex
chr12_-_8650529 0.91 ENST00000543467.5
microfibril associated protein 5
chr1_-_43389768 0.91 ENST00000372455.4
ENST00000372457.9
ENST00000290663.10
mediator complex subunit 8
chr1_+_159005953 0.91 ENST00000426592.6
interferon gamma inducible protein 16
chr19_-_56314788 0.87 ENST00000592509.5
ENST00000592679.5
ENST00000683990.1
ENST00000588442.5
ENST00000593106.5
ENST00000587492.5
zinc finger and SCAN domain containing 5A
chr12_+_120496101 0.87 ENST00000550178.1
ENST00000550845.5
ENST00000549989.1
ENST00000552870.1
ENST00000242577.11
dynein light chain LC8-type 1
chr12_-_118359105 0.87 ENST00000541186.5
ENST00000539872.5
TAO kinase 3
chr1_+_77779618 0.86 ENST00000370791.7
ENST00000443751.3
ENST00000645756.1
ENST00000643390.1
ENST00000642959.1
mitoguardin 1
chr12_-_8662808 0.84 ENST00000359478.7
ENST00000396549.6
microfibril associated protein 5
chr22_+_19479826 0.83 ENST00000437685.6
ENST00000263201.7
ENST00000404724.7
cell division cycle 45
chrX_-_33211540 0.83 ENST00000357033.9
dystrophin
chr11_+_74171266 0.83 ENST00000328257.13
ENST00000398427.6
protein phosphatase methylesterase 1
chrX_+_141002583 0.83 ENST00000449283.2
SPANX family member B1
chr11_-_74467531 0.82 ENST00000310128.9
ENST00000531854.5
ENST00000526855.1
ENST00000529425.5
potassium voltage-gated channel subfamily E regulatory subunit 3
chr8_-_100309904 0.81 ENST00000523481.5
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chrX_-_141698739 0.78 ENST00000370515.3
SPANX family member D
chr8_-_100309368 0.78 ENST00000523167.1
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr1_+_186828941 0.78 ENST00000367466.4
phospholipase A2 group IVA
chr14_+_64214136 0.71 ENST00000557084.1
ENST00000458046.6
spectrin repeat containing nuclear envelope protein 2
chr7_+_117014881 0.71 ENST00000422922.5
ENST00000432298.5
suppression of tumorigenicity 7
chr7_-_135510074 0.69 ENST00000428680.6
ENST00000423368.6
ENST00000451834.5
ENST00000361528.8
ENST00000541284.5
ENST00000315544.6
CCR4-NOT transcription complex subunit 4
chr3_-_197297523 0.69 ENST00000434148.1
ENST00000412364.2
ENST00000661013.1
ENST00000666007.1
ENST00000422288.6
ENST00000456699.6
ENST00000392380.6
ENST00000670935.1
ENST00000656087.1
ENST00000436682.6
ENST00000662727.1
ENST00000670455.1
ENST00000659221.1
ENST00000671185.1
ENST00000669565.1
ENST00000660898.1
ENST00000667971.1
ENST00000661453.1
discs large MAGUK scaffold protein 1
chr10_+_103245887 0.68 ENST00000441178.2
ribulose-5-phosphate-3-epimerase like 1
chr7_-_56051544 0.67 ENST00000395471.7
phosphoserine phosphatase
chr1_+_148889403 0.65 ENST00000464103.5
ENST00000534536.5
ENST00000369356.8
ENST00000369354.7
ENST00000369347.8
ENST00000369349.7
ENST00000369351.7
phosphodiesterase 4D interacting protein
chr15_-_79971164 0.64 ENST00000335661.6
ENST00000267953.4
ENST00000677151.1
BCL2 related protein A1
chr9_-_32552553 0.64 ENST00000379858.1
ENST00000360538.7
ENST00000681750.1
ENST00000680198.1
TOP1 binding arginine/serine rich protein, E3 ubiquitin ligase
novel protein
chr2_+_205682491 0.64 ENST00000360409.7
ENST00000450507.5
ENST00000357785.10
ENST00000417189.5
neuropilin 2
chr1_+_209827964 0.61 ENST00000491415.7
UTP25 small subunit processor component
chr8_-_100309926 0.60 ENST00000341084.7
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr22_+_19479457 0.59 ENST00000407835.6
ENST00000455750.6
cell division cycle 45
chr11_-_74170792 0.59 ENST00000680231.1
ENST00000681143.1
ENST00000679906.1
ENST00000681310.1
ENST00000414160.7
ENST00000538361.2
C2 domain containing 3 centriole elongation regulator
chr1_-_85276467 0.57 ENST00000648566.1
BCL10 immune signaling adaptor
chr6_+_24774925 0.57 ENST00000356509.7
ENST00000230056.8
geminin DNA replication inhibitor
chr4_-_158173042 0.56 ENST00000592057.1
ENST00000393807.9
golgi associated kinase 1B
chr14_+_73569266 0.55 ENST00000613168.1
acyl-CoA thioesterase 2
chr5_+_93583212 0.55 ENST00000327111.8
nuclear receptor subfamily 2 group F member 1
chr1_+_43969970 0.54 ENST00000255108.8
ENST00000396758.6
diphthamide biosynthesis 2
chr3_+_112086335 0.54 ENST00000431717.6
ENST00000480282.5
chromosome 3 open reading frame 52
chr14_+_32329256 0.49 ENST00000280979.9
A-kinase anchoring protein 6
chr11_+_1099730 0.48 ENST00000674892.1
mucin 2, oligomeric mucus/gel-forming
chr12_-_14885845 0.46 ENST00000539261.6
ENST00000228938.5
matrix Gla protein
chr19_+_55947832 0.45 ENST00000291971.7
ENST00000590542.1
NLR family pyrin domain containing 8
chr12_+_56752449 0.43 ENST00000554643.5
ENST00000556650.5
ENST00000554150.5
ENST00000554155.1
hydroxysteroid 17-beta dehydrogenase 6
chr2_+_151409878 0.42 ENST00000453091.6
ENST00000428287.6
ENST00000444746.7
ENST00000243326.9
ENST00000414861.6
replication timing regulatory factor 1
chr3_+_112086364 0.42 ENST00000264848.10
chromosome 3 open reading frame 52
chr11_-_74170975 0.41 ENST00000539061.6
ENST00000680645.1
ENST00000334126.12
ENST00000680718.1
C2 domain containing 3 centriole elongation regulator
chr4_-_158173004 0.40 ENST00000585682.6
golgi associated kinase 1B
chr6_-_30113086 0.39 ENST00000376734.4
tripartite motif containing 31
chr3_+_196867856 0.38 ENST00000445299.6
ENST00000323460.10
ENST00000419026.5
SUMO specific peptidase 5
chr1_-_168729187 0.38 ENST00000367817.4
dermatopontin
chr3_+_158110363 0.38 ENST00000683137.1
arginine and serine rich coiled-coil 1
chr6_+_29587455 0.37 ENST00000383640.4
olfactory receptor family 2 subfamily H member 2
chr4_+_94455245 0.37 ENST00000508216.5
ENST00000514743.5
PDZ and LIM domain 5
chr19_+_35358460 0.35 ENST00000327809.5
free fatty acid receptor 3
chr2_-_127675459 0.34 ENST00000355119.9
LIM zinc finger domain containing 2
chr2_-_177888728 0.33 ENST00000389683.7
phosphodiesterase 11A
chr2_-_169573766 0.32 ENST00000438035.5
ENST00000453929.6
FAST kinase domains 1
chr3_+_158110052 0.32 ENST00000295930.7
ENST00000471994.5
ENST00000482822.3
ENST00000476899.6
ENST00000683899.1
ENST00000684604.1
ENST00000682164.1
ENST00000464171.5
ENST00000611884.5
ENST00000312179.10
ENST00000475278.6
arginine and serine rich coiled-coil 1
chr12_+_55362975 0.31 ENST00000641576.1
olfactory receptor family 6 subfamily C member 75
chr11_-_66336396 0.29 ENST00000627248.1
ENST00000311320.9
Ras and Rab interactor 1
chr7_+_149838365 0.28 ENST00000460379.1
ENST00000223210.5
zinc finger protein 862
chr1_-_113871665 0.27 ENST00000528414.5
ENST00000460620.5
ENST00000359785.10
ENST00000420377.6
ENST00000525799.1
ENST00000538253.5
protein tyrosine phosphatase non-receptor type 22
chr4_+_77605807 0.26 ENST00000682537.1
C-X-C motif chemokine ligand 13
chr5_+_175861628 0.24 ENST00000509837.5
complexin 2
chr4_-_82848843 0.23 ENST00000511338.1
SEC31 homolog A, COPII coat complex component
chr5_+_162067858 0.22 ENST00000361925.9
gamma-aminobutyric acid type A receptor subunit gamma2
chr6_+_25754699 0.22 ENST00000439485.6
ENST00000377905.9
solute carrier family 17 member 4
chrX_-_11290478 0.21 ENST00000380717.7
Rho GTPase activating protein 6
chr8_-_142875797 0.21 ENST00000519285.5
cytochrome P450 family 11 subfamily B member 1
chr1_+_86993009 0.20 ENST00000370548.3
novel protein
chr1_+_81306096 0.18 ENST00000370721.5
ENST00000370727.5
ENST00000370725.5
ENST00000370723.5
ENST00000370728.5
ENST00000370730.5
adhesion G protein-coupled receptor L2
chr11_+_4704782 0.18 ENST00000380390.6
matrix metallopeptidase 26
chr2_-_169573856 0.17 ENST00000453153.7
ENST00000445210.1
FAST kinase domains 1
chr12_-_68159732 0.17 ENST00000229135.4
interferon gamma
chr5_+_137889437 0.16 ENST00000508638.5
ENST00000508883.6
ENST00000502810.5
polycystin 2 like 2, transient receptor potential cation channel
chr10_-_29634964 0.14 ENST00000375398.6
ENST00000355867.8
supervillin
chr5_+_156326735 0.13 ENST00000435422.7
sarcoglycan delta
chrX_-_130903187 0.10 ENST00000432489.5
ENST00000394363.6
ENST00000338144.8
ecto-NOX disulfide-thiol exchanger 2
chr12_+_851415 0.10 ENST00000675631.1
WNK lysine deficient protein kinase 1
chr6_+_30163188 0.08 ENST00000619857.4
tripartite motif containing 15
chrX_-_130903224 0.06 ENST00000370935.5
ecto-NOX disulfide-thiol exchanger 2
chr19_-_43198079 0.05 ENST00000597374.5
ENST00000599371.1
pregnancy specific beta-1-glycoprotein 4
chr8_-_132675533 0.04 ENST00000620350.5
ENST00000518642.5
ENST00000250173.5
leucine rich repeat containing 6
chr2_-_218659592 0.04 ENST00000411696.7
zinc finger protein 142
chr12_-_66803980 0.03 ENST00000539540.5
ENST00000540433.5
ENST00000541947.1
ENST00000538373.1
glutamate receptor interacting protein 1
chr12_-_56752311 0.03 ENST00000338193.11
ENST00000550770.1
DNA primase subunit 1
chr13_+_102656933 0.02 ENST00000650757.1
tripeptidyl peptidase 2
chr2_+_89959979 0.01 ENST00000453166.2
immunoglobulin kappa variable 2D-28

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 10.9 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
1.9 7.7 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
1.3 3.8 GO:2000863 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
0.8 3.4 GO:0021836 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.8 2.5 GO:0006533 aspartate catabolic process(GO:0006533)
0.6 1.9 GO:0015847 putrescine transport(GO:0015847)
0.6 3.4 GO:0097338 response to clozapine(GO:0097338)
0.5 2.4 GO:1900063 regulation of peroxisome organization(GO:1900063)
0.5 1.4 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) regulation of chromatin silencing at telomere(GO:0031938) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.4 2.2 GO:1901202 negative regulation of extracellular matrix assembly(GO:1901202)
0.4 1.3 GO:0051793 medium-chain fatty acid catabolic process(GO:0051793)
0.4 6.8 GO:0007021 tubulin complex assembly(GO:0007021)
0.3 1.0 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861)
0.3 2.6 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.3 4.3 GO:0001778 plasma membrane repair(GO:0001778)
0.3 0.8 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.2 3.0 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.2 1.7 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.2 1.7 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.2 1.8 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.2 1.0 GO:0021997 neural plate axis specification(GO:0021997)
0.2 0.8 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 0.6 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.2 0.7 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.2 1.0 GO:0035063 nuclear speck organization(GO:0035063)
0.2 2.3 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 6.5 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.4 GO:0006710 androgen catabolic process(GO:0006710)
0.1 0.6 GO:0042109 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) lymphotoxin A production(GO:0032641) positive regulation of mast cell cytokine production(GO:0032765) lymphotoxin A biosynthetic process(GO:0042109)
0.1 0.7 GO:0019323 pentose catabolic process(GO:0019323)
0.1 1.4 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.1 1.6 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.9 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 1.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.1 1.3 GO:0015871 choline transport(GO:0015871)
0.1 0.4 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 2.6 GO:0071420 cellular response to histamine(GO:0071420)
0.1 3.0 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.4 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.1 0.3 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 2.2 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.1 2.6 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.6 GO:0097490 sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.1 0.5 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.8 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.4 GO:0016926 protein desumoylation(GO:0016926)
0.1 0.9 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.3 GO:0070425 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.7 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.1 0.7 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:1901253 negative regulation of intracellular transport of viral material(GO:1901253)
0.0 1.5 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 2.2 GO:0009168 purine nucleoside monophosphate biosynthetic process(GO:0009127) purine ribonucleoside monophosphate biosynthetic process(GO:0009168)
0.0 0.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 1.1 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.2 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 1.1 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 2.2 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 2.2 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.9 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.8 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 1.6 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.0 0.5 GO:0001502 cartilage condensation(GO:0001502)
0.0 1.3 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 1.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.2 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.4 GO:0046597 negative regulation of viral transcription(GO:0032897) negative regulation of viral entry into host cell(GO:0046597)
0.0 0.6 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.7 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.0 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 10.9 GO:0060201 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.9 4.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.5 1.4 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.4 6.8 GO:0097512 cardiac myofibril(GO:0097512)
0.3 6.5 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.2 3.0 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.2 2.9 GO:0005687 U4 snRNP(GO:0005687)
0.2 3.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 0.5 GO:0070701 mucus layer(GO:0070701)
0.1 2.6 GO:0016342 catenin complex(GO:0016342)
0.1 0.9 GO:1990130 Iml1 complex(GO:1990130)
0.1 3.8 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.6 GO:0032449 CBM complex(GO:0032449)
0.1 3.7 GO:0031527 filopodium membrane(GO:0031527)
0.1 2.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 7.7 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 0.4 GO:0001940 male pronucleus(GO:0001940)
0.1 2.6 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.6 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 0.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 2.4 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 0.7 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.7 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.8 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 1.0 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.9 GO:0016592 mediator complex(GO:0016592)
0.0 0.9 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 15.0 GO:0009986 cell surface(GO:0009986)
0.0 2.5 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 6.9 GO:0016607 nuclear speck(GO:0016607)
0.0 1.1 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.8 GO:0031901 early endosome membrane(GO:0031901)
0.0 1.5 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 10.9 GO:0030348 syntaxin-3 binding(GO:0030348)
0.7 2.2 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.6 1.9 GO:0015203 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.6 3.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.4 3.4 GO:0008046 axon guidance receptor activity(GO:0008046)
0.4 1.3 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.4 2.5 GO:0004046 aminoacylase activity(GO:0004046)
0.3 1.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.3 7.7 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.3 2.4 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.2 6.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.2 0.7 GO:0004750 ribulose-phosphate 3-epimerase activity(GO:0004750)
0.2 3.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 2.3 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 0.7 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 1.6 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 2.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 4.3 GO:0000146 microfilament motor activity(GO:0000146)
0.1 1.7 GO:0003680 AT DNA binding(GO:0003680)
0.1 2.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.8 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1 1.4 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.1 2.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.6 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 1.6 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 6.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.2 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.1 0.6 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 6.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.2 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.4 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.1 1.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.6 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 0.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.0 0.8 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 1.7 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.7 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.4 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.6 GO:0051400 BH domain binding(GO:0051400)
0.0 0.6 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 1.0 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.4 GO:0043495 protein anchor(GO:0043495)
0.0 0.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.8 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 2.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 3.1 GO:0051015 actin filament binding(GO:0051015)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.0 GO:0003896 DNA primase activity(GO:0003896)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 13.2 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 11.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 2.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 4.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 5.9 PID NOTCH PATHWAY Notch signaling pathway
0.1 3.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 3.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.6 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 2.5 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.5 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.7 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.3 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.6 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.5 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 10.9 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2 7.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 3.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 3.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 3.4 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 1.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 5.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 2.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 2.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 0.8 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.6 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.9 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 3.8 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 1.8 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.7 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 1.7 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.6 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols