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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ATF5

Z-value: 0.62

Motif logo

Transcription factors associated with ATF5

Gene Symbol Gene ID Gene Info
ENSG00000169136.12 ATF5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ATF5hg38_v1_chr19_+_49929196_499292220.128.1e-02Click!

Activity profile of ATF5 motif

Sorted Z-values of ATF5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF5

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chrX_-_19965142 23.22 ENST00000340625.3
BCLAF1 and THRAP3 family member 3
chr11_+_92224801 15.68 ENST00000525166.6
FAT atypical cadherin 3
chr12_-_12338674 11.78 ENST00000545735.1
MANSC domain containing 1
chr14_+_92323154 11.56 ENST00000532405.6
ENST00000676001.1
ENST00000531433.5
solute carrier family 24 member 4
chr21_-_26843063 7.34 ENST00000678221.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr21_-_26843012 7.29 ENST00000517777.6
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr19_+_41003946 6.10 ENST00000593831.1
cytochrome P450 family 2 subfamily B member 6
chr1_-_145095528 6.09 ENST00000612199.4
ENST00000641863.1
SLIT-ROBO Rho GTPase activating protein 2B
chr12_+_53098846 5.64 ENST00000650247.1
ENST00000549628.1
insulin like growth factor binding protein 6
chr1_+_121184964 5.33 ENST00000367123.8
SLIT-ROBO Rho GTPase activating protein 2C
chr8_+_22605018 4.76 ENST00000389279.7
cell cycle and apoptosis regulator 2
chr8_+_22604632 4.17 ENST00000308511.8
ENST00000523801.5
ENST00000521301.5
cell cycle and apoptosis regulator 2
chr5_+_83471764 4.01 ENST00000512590.6
ENST00000513960.5
ENST00000513984.5
versican
chr1_+_15756659 3.98 ENST00000375771.5
filamin binding LIM protein 1
chr2_+_188974364 3.91 ENST00000304636.9
ENST00000317840.9
collagen type III alpha 1 chain
chr6_+_71886703 3.84 ENST00000491071.6
regulating synaptic membrane exocytosis 1
chr22_-_35840577 3.79 ENST00000405409.6
RNA binding fox-1 homolog 2
chr15_-_58014097 3.70 ENST00000559517.5
aldehyde dehydrogenase 1 family member A2
chr5_+_83471668 3.67 ENST00000342785.8
ENST00000343200.9
versican
chr5_+_83471925 3.63 ENST00000502527.2
versican
chr2_-_112784486 3.38 ENST00000263339.4
interleukin 1 alpha
chrX_+_104566193 3.35 ENST00000372582.6
interleukin 1 receptor accessory protein like 2
chr5_+_83471736 3.31 ENST00000265077.8
versican
chr12_+_53380141 3.09 ENST00000551969.5
ENST00000327443.9
Sp1 transcription factor
chr9_-_23826231 3.03 ENST00000397312.7
ELAV like RNA binding protein 2
chr3_-_99850976 2.99 ENST00000487087.5
filamin A interacting protein 1 like
chr1_+_209686173 2.86 ENST00000615289.4
ENST00000367028.6
ENST00000261465.5
hydroxysteroid 11-beta dehydrogenase 1
chr19_+_15049469 2.85 ENST00000427043.4
caspase 14
chr6_+_71886900 2.79 ENST00000517960.5
ENST00000518273.5
ENST00000522291.5
ENST00000521978.5
ENST00000520567.5
ENST00000264839.11
regulating synaptic membrane exocytosis 1
chr1_+_151766655 2.78 ENST00000400999.7
ornithine decarboxylase antizyme 3
chr9_+_2622053 2.78 ENST00000681306.1
ENST00000681618.1
very low density lipoprotein receptor
chr2_+_72916183 2.56 ENST00000394111.6
empty spiracles homeobox 1
chrX_-_130385656 2.56 ENST00000276218.4
ENST00000682440.1
G protein-coupled receptor 119
chr12_-_110502065 2.54 ENST00000447578.6
ENST00000546588.1
ENST00000360579.11
ENST00000549578.6
ENST00000549970.5
VPS29 retromer complex component
chr1_+_42463221 2.50 ENST00000654683.1
ENST00000667205.1
ENST00000655164.1
ENST00000657597.1
ENST00000667947.1
ENST00000668663.1
ENST00000660083.1
ENST00000655845.1
ENST00000671281.1
ENST00000664805.1
ENST00000654604.1
ENST00000655447.1
ENST00000661864.1
ENST00000665176.1
ENST00000670982.1
ENST00000668036.1
coiled-coil domain containing 30
chr2_-_187554473 2.46 ENST00000453013.5
ENST00000417013.5
tissue factor pathway inhibitor
chr4_-_82798735 2.43 ENST00000273908.4
ENST00000319540.9
stearoyl-CoA desaturase 5
chr7_-_42152444 2.43 ENST00000479210.1
GLI family zinc finger 3
chr12_+_110502307 2.42 ENST00000409778.7
ENST00000409300.6
RAD9 checkpoint clamp component B
chr1_-_183418364 2.37 ENST00000287713.7
nicotinamide nucleotide adenylyltransferase 2
chr7_-_42152396 2.34 ENST00000642432.1
ENST00000647255.1
ENST00000677288.1
GLI family zinc finger 3
chr9_+_2621766 2.30 ENST00000382100.8
very low density lipoprotein receptor
chr19_-_14979848 2.24 ENST00000594383.2
solute carrier family 1 member 6
chr18_-_812516 2.20 ENST00000584307.5
YES proto-oncogene 1, Src family tyrosine kinase
chr6_+_101181254 2.13 ENST00000682090.1
ENST00000421544.6
glutamate ionotropic receptor kainate type subunit 2
chr10_-_102419934 2.13 ENST00000406432.5
pleckstrin and Sec7 domain containing
chr1_-_16978276 2.08 ENST00000375534.7
microfibril associated protein 2
chr22_+_19131271 2.05 ENST00000399635.4
testis specific serine kinase 2
chr12_-_16608073 2.04 ENST00000441439.6
LIM domain only 3
chr17_+_35587478 2.03 ENST00000618940.4
adaptor related protein complex 2 subunit beta 1
chr12_-_52573816 2.02 ENST00000549343.5
ENST00000305620.3
keratin 74
chr12_+_32106762 2.01 ENST00000551848.1
ENST00000652176.1
BICD cargo adaptor 1
chr6_+_43770707 1.86 ENST00000324450.11
ENST00000417285.7
ENST00000413642.8
ENST00000372055.9
ENST00000482630.7
ENST00000425836.7
ENST00000372064.9
ENST00000372077.8
ENST00000519767.5
vascular endothelial growth factor A
chr22_-_35961623 1.84 ENST00000408983.2
RNA binding fox-1 homolog 2
chr4_+_83456045 1.81 ENST00000507349.5
ENST00000295491.9
ENST00000509970.5
ENST00000505719.1
mitochondrial ribosomal protein S18C
chr7_+_128758947 1.79 ENST00000493278.1
calumenin
chr6_-_62286161 1.78 ENST00000281156.5
KH RNA binding domain containing, signal transduction associated 2
chr6_-_31546552 1.78 ENST00000303892.10
ENST00000376151.4
ATPase H+ transporting V1 subunit G2
chr10_-_102419693 1.77 ENST00000611678.4
pleckstrin and Sec7 domain containing
chr12_-_16608183 1.76 ENST00000354662.5
ENST00000538051.5
LIM domain only 3
chr5_-_20575850 1.73 ENST00000507958.5
cadherin 18
chr2_-_25982471 1.70 ENST00000264712.8
kinesin family member 3C
chr2_-_26478113 1.66 ENST00000339598.8
otoferlin
chr15_+_80441229 1.66 ENST00000533983.5
ENST00000527771.5
ENST00000525103.1
aryl hydrocarbon receptor nuclear translocator 2
chr18_-_812230 1.65 ENST00000314574.5
YES proto-oncogene 1, Src family tyrosine kinase
chr17_-_48614628 1.64 ENST00000576562.1
homeobox B8
chr1_-_151346806 1.63 ENST00000392746.7
regulatory factor X5
chr15_+_74826603 1.63 ENST00000395018.6
complexin 3
chr16_-_30012294 1.58 ENST00000564979.5
ENST00000563378.5
double C2 domain alpha
chrX_+_155071414 1.57 ENST00000340647.8
BRCA1/BRCA2-containing complex subunit 3
chr12_+_56521951 1.55 ENST00000552247.6
RNA binding motif single stranded interacting protein 2
chrY_+_12904102 1.51 ENST00000360160.8
ENST00000454054.5
DEAD-box helicase 3 Y-linked
chr6_+_31897775 1.50 ENST00000469372.5
ENST00000497706.5
complement C2
chrX_-_129523436 1.49 ENST00000371123.5
ENST00000371121.5
ENST00000371122.8
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr2_-_187554351 1.49 ENST00000437725.5
ENST00000409676.5
ENST00000233156.9
ENST00000339091.8
ENST00000420747.1
tissue factor pathway inhibitor
chr2_-_190062721 1.48 ENST00000260950.5
myostatin
chr4_-_121164314 1.48 ENST00000057513.8
TNFAIP3 interacting protein 3
chr20_+_56412112 1.47 ENST00000360314.7
Cas scaffold protein family member 4
chr1_+_3690654 1.46 ENST00000378285.5
ENST00000378280.5
ENST00000378288.8
tumor protein p73
chr22_-_35840218 1.45 ENST00000414461.6
ENST00000416721.6
ENST00000449924.6
ENST00000262829.11
ENST00000397305.3
RNA binding fox-1 homolog 2
chr11_-_129192291 1.44 ENST00000682385.1
Rho GTPase activating protein 32
chr20_+_56412249 1.43 ENST00000679887.1
ENST00000434344.2
Cas scaffold protein family member 4
chr6_+_87155537 1.40 ENST00000369577.8
ENST00000518845.1
ENST00000339907.8
ENST00000496806.2
zinc finger protein 292
chr17_-_35943662 1.38 ENST00000618542.4
lysozyme like 6
chr12_+_56521990 1.37 ENST00000550726.5
ENST00000542360.1
RNA binding motif single stranded interacting protein 2
chr1_+_35557435 1.36 ENST00000373253.7
neurochondrin
chr7_+_136869077 1.36 ENST00000320658.9
ENST00000453373.5
ENST00000401861.1
cholinergic receptor muscarinic 2
chr11_+_63888515 1.35 ENST00000509502.6
ENST00000512060.1
microtubule affinity regulating kinase 2
chr14_+_70452161 1.34 ENST00000603540.2
ADAM metallopeptidase domain 21
chr19_-_18255385 1.33 ENST00000355502.7
ENST00000643046.1
novel protein
novel protein
chr2_-_113241683 1.32 ENST00000468980.3
paired box 8
chr17_-_35943707 1.28 ENST00000615905.5
lysozyme like 6
chr11_+_118606428 1.26 ENST00000361417.6
pleckstrin homology like domain family B member 1
chr2_+_172860038 1.23 ENST00000538974.5
ENST00000540783.5
Rap guanine nucleotide exchange factor 4
chr2_-_55050518 1.22 ENST00000317610.11
ENST00000357732.8
reticulon 4
chr2_-_100142575 1.22 ENST00000317233.8
ENST00000672204.1
ENST00000416492.5
ENST00000672857.1
ENST00000672756.2
AF4/FMR2 family member 3
chr16_-_58629816 1.19 ENST00000564557.1
ENST00000317147.10
ENST00000569240.5
ENST00000441024.6
CCR4-NOT transcription complex subunit 1
chr20_+_56412393 1.19 ENST00000679529.1
Cas scaffold protein family member 4
chr11_-_84720876 1.15 ENST00000648622.1
discs large MAGUK scaffold protein 2
chr19_+_4229502 1.14 ENST00000221847.6
Epstein-Barr virus induced 3
chrX_+_154144242 1.14 ENST00000369951.9
opsin 1, long wave sensitive
chr18_-_55422492 1.12 ENST00000561992.5
ENST00000630712.2
transcription factor 4
chr8_-_13276491 1.10 ENST00000512044.6
DLC1 Rho GTPase activating protein
chr4_-_174829212 1.10 ENST00000340217.5
ENST00000274093.8
glycine receptor alpha 3
chr14_+_79279403 1.07 ENST00000281127.11
neurexin 3
chr1_-_11803383 1.07 ENST00000641407.1
ENST00000376583.7
ENST00000423400.7
methylenetetrahydrofolate reductase
chr2_-_113241779 1.06 ENST00000497038.6
paired box 8
chr14_+_79279681 1.03 ENST00000679122.1
neurexin 3
chr11_-_129192198 1.03 ENST00000310343.13
Rho GTPase activating protein 32
chr9_+_19230680 1.02 ENST00000434457.7
DENN domain containing 4C
chr16_-_72172135 1.01 ENST00000537465.5
ENST00000237353.15
polyamine modulated factor 1 binding protein 1
chr12_-_24949026 1.00 ENST00000539780.5
ENST00000546285.1
ENST00000342945.9
ENST00000261192.12
branched chain amino acid transaminase 1
chr4_+_165873231 0.99 ENST00000061240.7
tolloid like 1
chr12_-_56449377 0.99 ENST00000229201.4
ENST00000553532.6
timeless circadian regulator
chr1_+_35557768 0.97 ENST00000356090.8
ENST00000373243.7
neurochondrin
chr5_+_132673983 0.97 ENST00000622422.1
ENST00000231449.7
ENST00000350025.2
interleukin 4
chr12_+_32107151 0.93 ENST00000548411.5
BICD cargo adaptor 1
chr8_-_21788159 0.92 ENST00000517892.5
ENST00000518077.5
GDNF family receptor alpha 2
chrX_+_154182596 0.92 ENST00000595290.6
opsin 1, medium wave sensitive
chr19_-_54360949 0.91 ENST00000622064.1
leukocyte associated immunoglobulin like receptor 1
chr22_-_36819479 0.91 ENST00000216200.9
parvalbumin
chr1_-_156490599 0.90 ENST00000360595.7
myocyte enhancer factor 2D
chr3_-_187736493 0.90 ENST00000232014.8
BCL6 transcription repressor
chrX_+_155071473 0.89 ENST00000369459.6
ENST00000369462.5
ENST00000330045.12
ENST00000411985.5
ENST00000399042.4
ENST00000620502.4
ENST00000630295.1
BRCA1/BRCA2-containing complex subunit 3
chr18_-_34224871 0.88 ENST00000261592.10
nucleolar protein 4
chr4_+_143336762 0.88 ENST00000262995.8
GRB2 associated binding protein 1
chr8_-_21788853 0.87 ENST00000524240.6
GDNF family receptor alpha 2
chr17_+_7630094 0.87 ENST00000441599.6
ENST00000380450.9
ENST00000416273.7
ENST00000575903.5
ENST00000571153.5
ENST00000575618.5
ENST00000576152.1
ENST00000576830.5
sex hormone binding globulin
chr17_-_7205116 0.87 ENST00000649520.1
ENST00000649186.1
discs large MAGUK scaffold protein 4
chr4_+_76251694 0.86 ENST00000510328.5
ENST00000424749.7
ENST00000502320.2
ENST00000515604.5
family with sequence similarity 47 member E
FAM47E-STBD1 readthrough
chr12_+_53380639 0.86 ENST00000426431.2
Sp1 transcription factor
chr3_+_19947316 0.85 ENST00000422242.1
RAB5A, member RAS oncogene family
chr9_+_19230435 0.81 ENST00000602925.5
DENN domain containing 4C
chr5_+_111223905 0.81 ENST00000512453.5
calcium/calmodulin dependent protein kinase IV
chr17_+_4771878 0.81 ENST00000270560.4
transmembrane 4 L six family member 5
chr12_-_71663827 0.80 ENST00000378743.9
ENST00000552037.1
zinc finger C3H1-type containing
chrX_+_123184260 0.79 ENST00000620443.2
ENST00000622768.5
ENST00000611689.4
glutamate ionotropic receptor AMPA type subunit 3
chr2_+_27051637 0.79 ENST00000451003.5
ENST00000360131.5
ENST00000323064.12
ATP/GTP binding protein like 5
chr19_+_42269219 0.79 ENST00000681038.1
capicua transcriptional repressor
chrX_+_12137409 0.78 ENST00000672010.1
FERM and PDZ domain containing 4
chr10_+_101354028 0.78 ENST00000393441.8
beta-transducin repeat containing E3 ubiquitin protein ligase
chr1_+_206203541 0.78 ENST00000573034.8
SLIT-ROBO Rho GTPase activating protein 2
chr2_-_208129824 0.76 ENST00000282141.4
crystallin gamma C
chr13_-_27969295 0.75 ENST00000381020.8
caudal type homeobox 2
chr18_-_55422306 0.75 ENST00000566777.5
ENST00000626584.2
transcription factor 4
chr6_+_29396555 0.72 ENST00000623183.1
olfactory receptor family 12 subfamily D member 2
chrX_+_154219756 0.72 ENST00000369929.8
opsin 1, medium wave sensitive 2
chr19_+_48465837 0.71 ENST00000595676.1
novel protein
chr10_+_101354083 0.65 ENST00000408038.6
ENST00000370187.8
beta-transducin repeat containing E3 ubiquitin protein ligase
chr12_+_56521798 0.65 ENST00000262031.10
RNA binding motif single stranded interacting protein 2
chr14_+_79280263 0.63 ENST00000555387.1
neurexin 3
chr9_+_79573162 0.63 ENST00000425506.5
TLE family member 4, transcriptional corepressor
chr4_-_67754335 0.62 ENST00000420975.2
ENST00000226413.5
gonadotropin releasing hormone receptor
chr17_+_42853232 0.59 ENST00000617500.4
amine oxidase copper containing 3
chr3_-_183427977 0.58 ENST00000473233.5
MCF.2 cell line derived transforming sequence-like 2
chr18_-_3845292 0.57 ENST00000400145.6
DLG associated protein 1
chr15_+_63189554 0.56 ENST00000559006.1
ENST00000321437.9
RAB8B, member RAS oncogene family
chr14_+_79279906 0.54 ENST00000428277.6
neurexin 3
chr8_-_60281388 0.54 ENST00000317995.5
carbonic anhydrase 8
chr4_+_70242583 0.53 ENST00000304954.3
casein kappa
chr11_+_123525822 0.50 ENST00000322282.11
ENST00000529750.5
GRAM domain containing 1B
chr19_-_45370384 0.47 ENST00000485403.6
ENST00000586856.1
ENST00000586131.6
ENST00000391945.10
ENST00000684407.1
ENST00000391944.8
ERCC excision repair 2, TFIIH core complex helicase subunit
chr1_+_158353965 0.47 ENST00000368154.5
ENST00000368155.7
ENST00000368156.5
ENST00000368157.5
ENST00000368160.7
ENST00000368161.7
CD1e molecule
chr8_+_78516329 0.47 ENST00000396418.7
ENST00000352966.9
cAMP-dependent protein kinase inhibitor alpha
chr5_-_149063021 0.43 ENST00000515425.6
SH3 domain and tetratricopeptide repeats 2
chr8_-_109680812 0.42 ENST00000528716.5
ENST00000527600.5
ENST00000531230.5
ENST00000532189.5
ENST00000534184.5
ENST00000408889.7
ENST00000533171.5
syntabulin
chrX_-_13817346 0.42 ENST00000356942.9
glycoprotein M6B
chr17_-_43125450 0.42 ENST00000494123.5
ENST00000468300.5
ENST00000471181.7
ENST00000652672.1
BRCA1 DNA repair associated
chr8_-_42207557 0.41 ENST00000220809.9
ENST00000429089.6
ENST00000519510.5
ENST00000429710.6
ENST00000524009.5
plasminogen activator, tissue type
chr5_+_137867852 0.40 ENST00000421631.6
ENST00000239926.9
myotilin
chr12_-_114683590 0.39 ENST00000257566.7
T-box transcription factor 3
chr3_-_101513175 0.36 ENST00000394091.5
ENST00000394094.6
ENST00000394095.7
ENST00000348610.3
ENST00000314261.11
SUMO specific peptidase 7
chr6_-_32176051 0.34 ENST00000375107.8
1-acylglycerol-3-phosphate O-acyltransferase 1
chr6_-_160664270 0.33 ENST00000316300.10
lipoprotein(a)
chr1_-_103108468 0.32 ENST00000512756.5
ENST00000461720.6
ENST00000358392.6
ENST00000353414.8
collagen type XI alpha 1 chain
chr21_-_43058941 0.31 ENST00000451248.5
ENST00000458223.5
cystathionine beta-synthase
chr14_+_79280056 0.30 ENST00000676811.1
neurexin 3
chrX_-_13817027 0.29 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
glycoprotein M6B
chr12_-_23951020 0.28 ENST00000441133.2
ENST00000545921.5
SRY-box transcription factor 5
chr1_+_202122910 0.26 ENST00000682545.1
ENST00000367282.6
ENST00000682887.1
G protein-coupled receptor 37 like 1
chr12_+_120446418 0.25 ENST00000551765.6
ENST00000229384.5
glutamyl-tRNA amidotransferase subunit C
chr8_-_94208548 0.24 ENST00000027335.8
ENST00000441892.6
ENST00000521491.1
cadherin 17
chr1_-_46132650 0.23 ENST00000372006.5
ENST00000425892.2
ENST00000420542.5
phosphoinositide-3-kinase regulatory subunit 3
chr11_+_63681444 0.23 ENST00000341307.6
ENST00000356000.7
ENST00000542238.5
reticulon 3
chr11_+_63681483 0.22 ENST00000339997.8
ENST00000540798.5
ENST00000545432.5
ENST00000543552.5
ENST00000377819.10
ENST00000537981.5
reticulon 3
chr15_-_75579248 0.22 ENST00000306726.6
ENST00000618819.5
protein tyrosine phosphatase non-receptor type 9
chr17_-_43125353 0.21 ENST00000476777.5
ENST00000491747.6
ENST00000478531.5
ENST00000357654.9
ENST00000477152.5
ENST00000618469.1
ENST00000352993.7
ENST00000493795.5
ENST00000493919.5
BRCA1 DNA repair associated
chr10_-_73655984 0.20 ENST00000394810.3
synaptopodin 2 like
chr12_-_114684151 0.20 ENST00000349155.7
T-box transcription factor 3
chr16_-_72093598 0.15 ENST00000268483.8
thioredoxin like 4B
chr2_-_87021844 0.15 ENST00000355705.4
ENST00000409310.6
plasminogen like B1
chr12_-_56636318 0.13 ENST00000549506.5
ENST00000379441.7
ENST00000551812.5
bromodomain adjacent to zinc finger domain 2A
chr1_-_158330957 0.11 ENST00000451207.5
CD1b molecule
chr15_-_23647848 0.10 ENST00000650528.1
MAGE family member L2
chr5_+_155013755 0.09 ENST00000435029.6
kinesin family member 4B
chr1_+_202122881 0.07 ENST00000683302.1
ENST00000683557.1
G protein-coupled receptor 37 like 1
chr1_-_54406385 0.06 ENST00000610401.5
single stranded DNA binding protein 3
chr5_+_137867868 0.03 ENST00000515645.1
myotilin
chr8_+_99013247 0.01 ENST00000441350.2
ENST00000357162.7
ENST00000358544.7
vacuolar protein sorting 13 homolog B

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0022012 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
1.3 3.9 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
1.0 7.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
1.0 2.9 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.9 2.8 GO:0015847 putrescine transport(GO:0015847)
0.8 14.0 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.8 5.3 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.7 5.1 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.7 8.9 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.7 3.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.6 1.9 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.6 14.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.6 2.4 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.6 2.4 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.6 11.6 GO:0097186 amelogenesis(GO:0097186)
0.5 3.8 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.5 2.7 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.4 2.2 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.4 3.9 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.4 3.4 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.4 3.7 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.4 6.1 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.4 1.5 GO:1902725 negative regulation of satellite cell differentiation(GO:1902725)
0.4 2.5 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.3 1.7 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.3 2.1 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.3 6.6 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.3 4.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.3 1.0 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) cellular response to mercury ion(GO:0071288)
0.3 1.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.2 0.9 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.2 0.6 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2 1.0 GO:0009099 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2 2.6 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 0.6 GO:0060932 mammary placode formation(GO:0060596) His-Purkinje system cell differentiation(GO:0060932)
0.2 0.6 GO:0051461 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.2 1.1 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.2 1.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.2 1.7 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.2 1.0 GO:0072719 cellular response to cisplatin(GO:0072719)
0.2 2.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 1.8 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.2 0.5 GO:0032289 central nervous system myelin formation(GO:0032289)
0.2 0.8 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.2 5.6 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2 2.1 GO:0051967 regulation of short-term neuronal synaptic plasticity(GO:0048172) negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.2 2.4 GO:0000076 DNA replication checkpoint(GO:0000076)
0.1 1.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 3.8 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.1 0.6 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.1 2.9 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.1 2.5 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 0.8 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 1.5 GO:0000733 DNA strand renaturation(GO:0000733)
0.1 1.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.1 3.6 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 1.3 GO:1904259 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 1.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 0.8 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.1 17.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.8 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.8 GO:0035608 protein deglutamylation(GO:0035608)
0.1 0.8 GO:0021815 cell motility involved in cerebral cortex radial glia guided migration(GO:0021814) modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.1 0.3 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 0.9 GO:2000821 regulation of grooming behavior(GO:2000821)
0.1 1.1 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 2.1 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 1.1 GO:0007625 grooming behavior(GO:0007625)
0.1 0.7 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.9 GO:0007512 adult heart development(GO:0007512)
0.1 1.5 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.3 GO:0043418 cysteine biosynthetic process from serine(GO:0006535) cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) homocysteine catabolic process(GO:0043418) L-cysteine metabolic process(GO:0046439)
0.1 0.6 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 1.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 2.3 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.0 1.8 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 3.3 GO:0016079 synaptic vesicle exocytosis(GO:0016079)
0.0 0.3 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 4.9 GO:0070268 cornification(GO:0070268)
0.0 2.4 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 0.4 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.0 0.9 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 0.2 GO:0035989 tendon development(GO:0035989)
0.0 1.7 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 2.5 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 1.2 GO:0017156 calcium ion regulated exocytosis(GO:0017156)
0.0 1.3 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 1.8 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 1.2 GO:0035116 embryonic hindlimb morphogenesis(GO:0035116)
0.0 0.8 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 1.5 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 1.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.3 GO:0034374 low-density lipoprotein particle remodeling(GO:0034374)
0.0 1.8 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.0 2.0 GO:0007286 spermatid development(GO:0007286)
0.0 0.4 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.5 GO:0006730 one-carbon metabolic process(GO:0006730)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 8.9 GO:0044609 DBIRD complex(GO:0044609)
0.8 2.5 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.5 2.9 GO:0045298 tubulin complex(GO:0045298)
0.5 2.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.5 5.6 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.3 4.1 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 2.5 GO:0070552 BRISC complex(GO:0070552)
0.2 1.4 GO:0032279 asymmetric synapse(GO:0032279)
0.2 2.7 GO:0097524 sperm plasma membrane(GO:0097524)
0.2 1.5 GO:0016589 NURF complex(GO:0016589)
0.2 1.8 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.2 1.8 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 5.1 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 6.5 GO:0097542 ciliary tip(GO:0097542)
0.1 1.3 GO:0045180 basal cortex(GO:0045180)
0.1 0.5 GO:0071817 MMXD complex(GO:0071817)
0.1 6.6 GO:0048786 presynaptic active zone(GO:0048786)
0.1 14.6 GO:0005604 basement membrane(GO:0005604)
0.1 4.9 GO:0045095 keratin filament(GO:0045095)
0.1 1.3 GO:0097427 microtubule bundle(GO:0097427)
0.1 14.6 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.8 GO:0044327 dendritic spine head(GO:0044327)
0.1 2.1 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.1 1.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 0.8 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.1 0.3 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 1.8 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1 1.7 GO:0036020 endolysosome membrane(GO:0036020)
0.1 2.1 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 3.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 1.8 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 3.9 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 0.6 GO:0051286 cell tip(GO:0051286)
0.0 1.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 4.0 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 3.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 5.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.4 GO:0097433 dense body(GO:0097433)
0.0 3.8 GO:0005884 actin filament(GO:0005884)
0.0 3.1 GO:0043197 dendritic spine(GO:0043197)
0.0 2.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 6.1 GO:0098793 presynapse(GO:0098793)
0.0 1.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.2 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 1.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.9 GO:0005657 replication fork(GO:0005657)
0.0 1.1 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 2.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.1 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0034358 plasma lipoprotein particle(GO:0034358) lipoprotein particle(GO:1990777)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 11.6 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
1.7 5.1 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
1.0 2.9 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.9 2.8 GO:0015203 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
0.7 3.3 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.6 2.4 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.6 2.4 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.6 2.9 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.5 5.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.4 2.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.4 2.7 GO:0003796 lysozyme activity(GO:0003796)
0.4 2.0 GO:1990254 keratin filament binding(GO:1990254)
0.4 14.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.4 1.9 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.3 1.0 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.3 6.1 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.3 3.7 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.3 3.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.3 2.4 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.3 1.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.3 8.9 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.3 1.8 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.2 2.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 1.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 3.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.2 1.0 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 1.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.2 2.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 4.0 GO:0031005 filamin binding(GO:0031005)
0.2 2.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.2 4.4 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.6 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.1 0.9 GO:0005497 androgen binding(GO:0005497)
0.1 8.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.7 GO:0009881 photoreceptor activity(GO:0009881)
0.1 12.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 1.5 GO:0036310 annealing helicase activity(GO:0036310)
0.1 17.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.5 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 1.7 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.1 0.3 GO:0036505 prosaposin receptor activity(GO:0036505)
0.1 0.3 GO:0098809 oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.1 0.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 2.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 1.9 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.3 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 2.6 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 1.7 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 5.5 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.1 1.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.6 GO:0030883 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.1 2.1 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 2.9 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 2.4 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.1 0.5 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 1.3 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.6 GO:0030911 TPR domain binding(GO:0030911)
0.0 1.6 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 3.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 5.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 1.5 GO:0031593 polyubiquitin binding(GO:0031593)
0.0 1.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.8 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 21.7 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.2 GO:0030552 cAMP binding(GO:0030552)
0.0 1.8 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 2.5 GO:0008565 protein transporter activity(GO:0008565)
0.0 6.3 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.9 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 2.5 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.4 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.4 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 14.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 5.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 1.9 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 3.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 4.1 NABA COLLAGENS Genes encoding collagen proteins
0.1 3.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 3.4 PID IL1 PATHWAY IL1-mediated signaling events
0.1 17.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 4.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 4.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.8 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.9 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 3.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.9 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 5.6 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.1 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 2.5 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 1.4 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.5 PID P73PATHWAY p73 transcription factor network
0.0 0.2 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 14.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 6.1 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.3 6.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.3 2.8 REACTOME OPSINS Genes involved in Opsins
0.2 3.8 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.2 5.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.2 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.9 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 2.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 3.9 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 4.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 2.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 11.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 5.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 3.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 1.8 REACTOME KINESINS Genes involved in Kinesins
0.1 2.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 0.6 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 1.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 2.8 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 3.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 2.8 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 1.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 1.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.2 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.2 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.9 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.1 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.8 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.6 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.7 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 1.2 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism