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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ATF7

Z-value: 3.40

Motif logo

Transcription factors associated with ATF7

Gene Symbol Gene ID Gene Info
ENSG00000170653.19 ATF7

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ATF7hg38_v1_chr12_-_53626323_536264130.073.4e-01Click!

Activity profile of ATF7 motif

Sorted Z-values of ATF7 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ATF7

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr12_+_52949107 16.12 ENST00000388835.4
keratin 18
chr1_+_26169891 12.03 ENST00000374266.7
ENST00000270812.6
zinc finger protein 593
chr8_+_97775775 11.07 ENST00000521545.7
lysosomal protein transmembrane 4 beta
chr15_-_90994494 10.85 ENST00000559811.1
ENST00000442656.6
ENST00000557905.5
ENST00000394249.8
protein regulator of cytokinesis 1
chr16_+_3018390 9.37 ENST00000573001.5
TNF receptor superfamily member 12A
chr4_-_121823843 8.13 ENST00000274026.10
cyclin A2
chr19_+_10251901 7.70 ENST00000592514.5
ENST00000307422.9
ENST00000590150.5
ENST00000590669.5
mitochondrial ribosomal protein L4
chr17_+_7252268 7.48 ENST00000396628.6
ENST00000574993.5
ENST00000573657.5
elongator acetyltransferase complex subunit 5
chr6_-_3157536 7.42 ENST00000333628.4
tubulin beta 2A class IIa
chr11_+_12674397 7.01 ENST00000527636.7
TEA domain transcription factor 1
chr12_+_12891554 6.72 ENST00000014914.6
G protein-coupled receptor class C group 5 member A
chr17_+_7252237 6.71 ENST00000570500.5
elongator acetyltransferase complex subunit 5
chr7_+_55951852 6.53 ENST00000285298.9
mitochondrial ribosomal protein S17
chr4_-_103198331 6.52 ENST00000265148.9
ENST00000514974.1
centromere protein E
chr19_+_10252206 6.52 ENST00000253099.11
ENST00000393733.6
ENST00000588502.5
mitochondrial ribosomal protein L4
chr7_+_55951919 6.51 ENST00000443449.1
mitochondrial ribosomal protein S17
chr14_-_103522696 6.31 ENST00000553878.5
ENST00000348956.7
ENST00000557530.1
creatine kinase B
chr16_+_81007189 6.27 ENST00000439957.7
ENST00000305850.10
ENST00000393335.7
ENST00000428963.6
ENST00000564669.5
centromere protein N
chr4_-_103198371 6.14 ENST00000611174.4
ENST00000380026.8
centromere protein E
chr1_-_16156059 6.07 ENST00000358432.8
EPH receptor A2
chr17_+_7252024 5.69 ENST00000573513.5
ENST00000354429.6
ENST00000574255.5
ENST00000356683.6
ENST00000396627.6
elongator acetyltransferase complex subunit 5
chr16_-_3717505 5.67 ENST00000538171.5
ENST00000246957.10
TNF receptor associated protein 1
chr17_+_8249273 5.53 ENST00000584044.5
ENST00000314666.11
ENST00000581242.3
phosphoribosylformylglycinamidine synthase
chr11_+_4094775 5.52 ENST00000300738.10
ribonucleotide reductase catalytic subunit M1
chr7_+_5592805 5.48 ENST00000382361.8
fascin actin-bundling protein 1
chr7_-_129952631 5.40 ENST00000473814.6
ENST00000490974.1
ubiquitin conjugating enzyme E2 H
chr4_+_145098269 5.33 ENST00000502586.5
ENST00000296577.9
ATP binding cassette subfamily E member 1
chr6_-_31806937 5.32 ENST00000375661.6
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr14_+_93184951 5.25 ENST00000283534.4
ENST00000557574.1
transmembrane protein 251
novel protein
chr2_-_97094882 5.17 ENST00000414820.6
ENST00000272610.3
fumarylacetoacetate hydrolase domain containing 2B
chr11_+_18322253 5.17 ENST00000453096.6
general transcription factor IIH subunit 1
chrX_+_150980504 5.15 ENST00000419110.5
high mobility group box 3
chr10_+_122163590 5.13 ENST00000368999.5
transforming acidic coiled-coil containing protein 2
chr10_+_122163426 5.09 ENST00000360561.7
transforming acidic coiled-coil containing protein 2
chr3_+_62318983 5.04 ENST00000232519.9
ENST00000462069.6
ENST00000465142.5
chromosome 3 open reading frame 14
chr3_+_62319037 5.03 ENST00000494481.5
chromosome 3 open reading frame 14
chr3_+_158571215 4.95 ENST00000498592.6
ENST00000478894.7
myeloid leukemia factor 1
chr1_+_156061142 4.92 ENST00000361084.10
RAB25, member RAS oncogene family
chr18_+_2571529 4.78 ENST00000261597.9
ENST00000575515.1
NDC80 kinetochore complex component
chr10_+_122163672 4.70 ENST00000369004.7
ENST00000260733.7
transforming acidic coiled-coil containing protein 2
chr19_+_35545681 4.69 ENST00000392205.2
transmembrane protein 147
chr14_+_67619911 4.58 ENST00000261783.4
arginase 2
chr21_-_41767042 4.34 ENST00000332512.8
receptor interacting serine/threonine kinase 4
chr1_+_1001002 4.25 ENST00000624697.4
ENST00000624652.1
ISG15 ubiquitin like modifier
chr11_-_28108109 4.15 ENST00000263181.7
kinesin family member 18A
chr4_-_145098183 4.06 ENST00000451299.6
ENST00000507656.6
ENST00000309439.9
anaphase promoting complex subunit 10
chr1_-_1349368 4.01 ENST00000378888.10
dishevelled segment polarity protein 1
chr12_-_6753134 3.96 ENST00000203630.10
myeloid leukemia factor 2
chr16_+_29900474 3.95 ENST00000308748.10
aspartate beta-hydroxylase domain containing 1
chr21_-_41767071 3.91 ENST00000352483.3
receptor interacting serine/threonine kinase 4
chr14_+_93185304 3.71 ENST00000415050.3
transmembrane protein 251
chr16_+_1989949 3.66 ENST00000248121.7
ENST00000618464.1
synaptogyrin 3
chr9_-_137459296 3.62 ENST00000371472.6
ENST00000371475.9
ENST00000371473.7
ENST00000371474.7
ENST00000437259.5
ENST00000265663.12
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr9_-_2844058 3.56 ENST00000397885.3
pumilio RNA binding family member 3
chr4_-_145098135 3.51 ENST00000502847.1
ENST00000513054.5
anaphase promoting complex subunit 10
chr11_+_3797819 3.50 ENST00000396986.6
ENST00000300730.10
ENST00000396993.8
ENST00000532523.5
ENST00000459679.5
ENST00000464229.5
ENST00000464261.5
ENST00000490830.5
ENST00000464906.6
ENST00000464441.5
post-GPI attachment to proteins 2
chr19_+_35545575 3.47 ENST00000222284.10
ENST00000392204.6
transmembrane protein 147
chr11_-_33161461 3.47 ENST00000323959.9
ENST00000431742.2
ENST00000524827.6
cleavage stimulation factor subunit 3
chr4_-_145098541 3.44 ENST00000613466.4
ENST00000514390.5
anaphase promoting complex subunit 10
chr17_+_35587239 3.42 ENST00000621914.4
ENST00000621668.4
ENST00000616681.4
ENST00000612035.4
ENST00000610402.5
ENST00000614600.4
ENST00000590432.5
ENST00000612116.5
adaptor related protein complex 2 subunit beta 1
chr22_+_31944500 3.33 ENST00000397492.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
chr8_+_26291758 3.31 ENST00000522535.5
ENST00000665949.1
protein phosphatase 2 regulatory subunit Balpha
chr19_+_35629027 3.26 ENST00000588161.5
ENST00000262633.9
ENST00000592202.5
ENST00000586618.5
ENST00000589559.5
RNA binding motif protein 42
chr12_-_57772087 3.21 ENST00000324871.12
ENST00000257848.7
methyltransferase like 1
chr22_+_31944527 3.19 ENST00000248975.6
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
chr7_-_73738792 3.19 ENST00000222800.8
ENST00000458339.6
abhydrolase domain containing 11
chr3_+_158571171 3.17 ENST00000484955.5
ENST00000359117.9
ENST00000619577.5
ENST00000471745.5
ENST00000477042.6
ENST00000650753.1
ENST00000651984.1
ENST00000355893.11
ENST00000466246.7
ENST00000469452.5
ENST00000482628.5
myeloid leukemia factor 1
chr2_-_240025380 3.11 ENST00000676782.1
ENST00000677407.1
ENST00000678914.1
ENST00000677294.1
ENST00000676491.1
ENST00000677567.1
ENST00000679158.1
ENST00000448880.6
ENST00000677263.1
ENST00000678289.1
ENST00000678737.1
NADH:ubiquinone oxidoreductase subunit A10
chr3_+_44761765 3.07 ENST00000326047.9
kinesin family member 15
chr6_-_127459364 3.07 ENST00000487331.2
ENST00000483725.8
KIAA0408
chr9_-_33001522 3.05 ENST00000463596.6
ENST00000673598.1
ENST00000477119.2
ENST00000673416.1
ENST00000309615.8
ENST00000397172.8
ENST00000379813.7
ENST00000379819.6
ENST00000379825.7
ENST00000379817.7
ENST00000672438.1
ENST00000476858.6
aprataxin
chr3_+_158571153 2.99 ENST00000491767.6
ENST00000618075.4
myeloid leukemia factor 1
chr22_+_39502237 2.99 ENST00000325301.7
mitochondrial elongation factor 1
chr9_+_94726657 2.96 ENST00000375315.8
ENST00000277198.6
ENST00000297979.9
aminopeptidase O (putative)
chr3_-_108222383 2.96 ENST00000264538.4
intraflagellar transport 57
chr11_+_18322541 2.95 ENST00000534641.5
ENST00000265963.9
ENST00000525831.5
general transcription factor IIH subunit 1
chr2_-_240025299 2.91 ENST00000404554.5
ENST00000407129.3
ENST00000307300.8
ENST00000678455.1
ENST00000444548.6
ENST00000252711.7
ENST00000620965.5
ENST00000443626.5
NADH:ubiquinone oxidoreductase subunit A10
chr12_+_112418928 2.91 ENST00000351677.7
ENST00000639857.1
protein tyrosine phosphatase non-receptor type 11
chr17_+_782340 2.84 ENST00000304478.9
mitochondrial rRNA methyltransferase 3
chr1_-_114581589 2.77 ENST00000369541.4
BCAS2 pre-mRNA processing factor
chr10_+_132537778 2.75 ENST00000368594.8
inositol polyphosphate-5-phosphatase A
chr12_+_112418976 2.67 ENST00000635625.1
protein tyrosine phosphatase non-receptor type 11
chr18_+_80109236 2.64 ENST00000262198.9
ENST00000560752.5
ADNP homeobox 2
chr19_+_35629107 2.63 ENST00000589871.1
RNA binding motif protein 42
chr3_+_170357647 2.58 ENST00000476188.5
ENST00000259119.9
ENST00000426052.6
SKI like proto-oncogene
chr19_+_45001430 2.57 ENST00000625761.2
ENST00000505236.1
ENST00000221452.13
RELB proto-oncogene, NF-kB subunit
chr19_+_35358460 2.56 ENST00000327809.5
free fatty acid receptor 3
chr19_+_8390316 2.56 ENST00000328024.11
ENST00000601897.1
ENST00000594216.1
RAB11B, member RAS oncogene family
chr19_-_7943648 2.54 ENST00000597926.1
ENST00000270538.8
translocase of inner mitochondrial membrane 44
chr8_+_26291494 2.53 ENST00000380737.8
ENST00000524169.5
protein phosphatase 2 regulatory subunit Balpha
chr19_+_57363469 2.51 ENST00000282282.4
ENST00000543226.2
ENST00000596755.1
ENST00000597658.1
zinc finger protein 547
trafficking protein particle complex 2B
novel protein
chr6_+_41921491 2.49 ENST00000230340.9
bystin like
chr17_+_35587478 2.47 ENST00000618940.4
adaptor related protein complex 2 subunit beta 1
chr14_+_92923143 2.46 ENST00000216492.10
ENST00000334654.4
chromogranin A
chr17_+_31094880 2.43 ENST00000487476.5
ENST00000356175.7
neurofibromin 1
chr14_-_20333306 2.42 ENST00000353689.8
ENST00000437553.6
cyclin B1 interacting protein 1
chr4_+_1871373 2.42 ENST00000508803.6
ENST00000507820.5
ENST00000514045.5
nuclear receptor binding SET domain protein 2
chr4_+_84583037 2.41 ENST00000295887.6
CDP-diacylglycerol synthase 1
chr14_-_20333268 2.37 ENST00000358932.9
ENST00000557665.5
cyclin B1 interacting protein 1
chr17_+_31094969 2.37 ENST00000431387.8
ENST00000358273.9
neurofibromin 1
chrX_+_111096136 2.33 ENST00000372007.10
p21 (RAC1) activated kinase 3
chr9_-_96619783 2.31 ENST00000375241.6
cell division cycle 14B
chr7_+_140697144 2.27 ENST00000476470.5
ENST00000471136.5
NADH:ubiquinone oxidoreductase subunit B2
chr15_-_66497708 2.26 ENST00000566658.1
ENST00000563480.6
ENST00000395589.6
ENST00000316634.6
ENST00000307979.7
small nuclear RNA activating complex polypeptide 5
chr21_+_43789522 2.21 ENST00000497547.2
ribosomal RNA processing 1
chr11_+_66843413 2.19 ENST00000524506.5
ENST00000309657.8
Ras converting CAAX endopeptidase 1
chr11_+_108665045 2.16 ENST00000322536.8
DEAD-box helicase 10
chr19_+_12945839 2.13 ENST00000586534.6
ENST00000316856.7
ENST00000592268.5
RAD23 homolog A, nucleotide excision repair protein
chr19_+_43596480 2.12 ENST00000533118.5
zinc finger protein 576
chr12_-_121016345 2.08 ENST00000535367.1
ENST00000538296.5
ENST00000288757.7
ENST00000539736.5
ENST00000537817.5
chromosome 12 open reading frame 43
chr19_+_52190006 2.06 ENST00000454220.6
ENST00000322088.11
ENST00000477989.1
ENST00000628959.1
protein phosphatase 2 scaffold subunit Aalpha
chr10_+_35195843 2.05 ENST00000488741.5
ENST00000474931.5
ENST00000468236.5
ENST00000344351.5
ENST00000490511.1
cAMP responsive element modulator
chr11_+_18394586 2.02 ENST00000227157.8
ENST00000478970.6
ENST00000495052.5
lactate dehydrogenase A
chr7_+_140696665 2.02 ENST00000476279.5
ENST00000461457.1
ENST00000465506.5
NADH:ubiquinone oxidoreductase subunit B2
chr19_+_35612729 2.01 ENST00000203166.10
HAUS augmin like complex subunit 5
chr17_+_28744002 1.96 ENST00000618771.1
ENST00000262395.10
ENST00000422344.5
TNF receptor associated factor 4
chr8_+_30156359 1.96 ENST00000520829.5
ENST00000221114.8
dynactin subunit 6
chr2_-_219399981 1.95 ENST00000519905.1
ENST00000523282.5
ENST00000434339.5
ENST00000457935.5
aspartyl aminopeptidase
chr12_-_56300299 1.93 ENST00000552688.5
ENST00000548041.5
ENST00000551137.5
ENST00000551968.5
ENST00000351328.8
ENST00000542324.6
ENST00000546930.5
ENST00000549221.5
ENST00000550159.5
ENST00000550734.5
citrate synthase
chr12_-_56300358 1.93 ENST00000550655.5
ENST00000548567.5
ENST00000551430.6
citrate synthase
chr11_-_123654939 1.90 ENST00000657191.1
sodium voltage-gated channel beta subunit 3
chr19_+_35995176 1.89 ENST00000378887.4
succinate dehydrogenase complex assembly factor 1
chr18_-_36067524 1.87 ENST00000590898.5
ENST00000357384.8
ENST00000399022.9
ENST00000588737.5
regulation of nuclear pre-mRNA domain containing 1A
chr19_-_42255119 1.86 ENST00000222329.9
ENST00000594664.1
ETS2 repressor factor
novel protein
chr22_+_39502320 1.86 ENST00000404569.5
mitochondrial elongation factor 1
chr20_+_35615812 1.84 ENST00000679710.1
ENST00000374273.8
sperm associated antigen 4
chr7_-_129952901 1.83 ENST00000472396.5
ENST00000355621.8
ubiquitin conjugating enzyme E2 H
chr7_+_140696696 1.82 ENST00000247866.9
ENST00000464566.5
NADH:ubiquinone oxidoreductase subunit B2
chrX_+_111096211 1.80 ENST00000372010.5
ENST00000519681.5
p21 (RAC1) activated kinase 3
chr22_+_31122923 1.80 ENST00000620191.4
ENST00000412277.6
ENST00000412985.5
ENST00000331075.10
ENST00000420017.5
ENST00000400294.6
ENST00000405300.5
ENST00000404390.7
inositol polyphosphate-5-phosphatase J
chr12_-_93441886 1.78 ENST00000552442.1
ENST00000550657.1
ENST00000318066.7
ubiquitin conjugating enzyme E2 N
chr19_+_57320461 1.75 ENST00000321545.5
zinc finger protein 543
chr17_+_70075215 1.74 ENST00000283936.5
ENST00000615244.4
ENST00000392671.6
potassium inwardly rectifying channel subfamily J member 16
chr4_+_127880876 1.70 ENST00000270861.10
ENST00000515069.5
ENST00000513090.5
ENST00000507249.5
polo like kinase 4
chr11_-_13495984 1.68 ENST00000282091.6
parathyroid hormone
chr20_+_5911501 1.68 ENST00000378961.9
ENST00000455042.1
chromogranin B
chr17_+_43398984 1.67 ENST00000320033.5
ADP ribosylation factor like GTPase 4D
chr7_+_140696956 1.66 ENST00000460088.5
ENST00000472695.5
NADH:ubiquinone oxidoreductase subunit B2
chr11_-_111879425 1.65 ENST00000622211.4
novel protein
chr17_-_782317 1.63 ENST00000301329.10
glyoxalase domain containing 4
chr1_+_2073986 1.59 ENST00000461106.6
protein kinase C zeta
chr11_-_3797746 1.58 ENST00000359171.8
nucleoporin 98 and 96 precursor
chr5_-_58460076 1.56 ENST00000274289.8
ENST00000617412.1
polo like kinase 2
chr17_+_28744034 1.55 ENST00000444415.7
ENST00000262396.10
TNF receptor associated factor 4
chr2_-_219543793 1.54 ENST00000243776.11
chondroitin polymerizing factor
chr12_-_112418819 1.54 ENST00000551291.6
ribosomal protein L6
chr17_-_21042901 1.46 ENST00000261497.9
ubiquitin specific peptidase 22
chr8_+_42338454 1.44 ENST00000532157.5
ENST00000520008.5
DNA polymerase beta
chr4_+_141220881 1.42 ENST00000262990.9
ENST00000512809.5
ENST00000503649.5
ENST00000512738.5
zinc finger protein 330
chr4_-_2008835 1.40 ENST00000411649.3
ENST00000382882.9
ENST00000431323.6
negative elongation factor complex member A
chr19_+_49677055 1.38 ENST00000534465.6
ENST00000391851.8
ENST00000610806.4
protein arginine methyltransferase 1
chr1_-_228103235 1.38 ENST00000272139.5
chromosome 1 open reading frame 35
chr12_+_6904733 1.37 ENST00000007969.12
ENST00000622489.4
ENST00000443597.7
ENST00000323702.9
leucine rich repeat containing 23
chr6_-_106325616 1.37 ENST00000360666.6
autophagy related 5
chr11_-_31817937 1.35 ENST00000638965.1
ENST00000241001.13
ENST00000638914.3
ENST00000379132.8
ENST00000379129.7
paired box 6
chr17_+_70075317 1.31 ENST00000589377.1
potassium inwardly rectifying channel subfamily J member 16
chr11_-_31817904 1.29 ENST00000423822.7
paired box 6
chr17_-_782253 1.26 ENST00000628529.2
ENST00000625892.1
ENST00000301328.9
ENST00000576419.1
glyoxalase domain containing 4
chr2_-_219309484 1.24 ENST00000409251.7
ENST00000451506.5
ENST00000446182.5
protein tyrosine phosphatase receptor type N
chr10_+_35195124 1.24 ENST00000487763.5
ENST00000473940.5
ENST00000488328.5
ENST00000356917.9
cAMP responsive element modulator
chr16_+_19067989 1.23 ENST00000569127.1
coenzyme Q7, hydroxylase
chr12_+_53985138 1.23 ENST00000303460.5
homeobox C10
chr7_+_152759744 1.20 ENST00000377776.7
ENST00000256001.13
ENST00000397282.2
actin related protein 3B
chr5_-_113434978 1.18 ENST00000390666.4
testis specific serine kinase 1B
chr2_-_20823048 1.14 ENST00000402479.6
ENST00000237822.8
ENST00000626491.2
ENST00000432947.1
ENST00000403006.6
ENST00000419825.2
ENST00000381090.7
ENST00000412261.5
ENST00000619656.4
ENST00000541941.5
ENST00000440866.6
ENST00000435420.6
lipid droplet associated hydrolase
chr1_+_109984756 1.14 ENST00000393614.8
ENST00000369799.10
adenosylhomocysteinase like 1
chr11_-_13496018 1.12 ENST00000529816.1
parathyroid hormone
chr19_-_51002527 1.11 ENST00000595238.1
ENST00000600767.5
kallikrein related peptidase 8
chrX_+_149781930 1.11 ENST00000243314.5
MAGE family member A9
chr1_+_6624842 1.09 ENST00000054650.8
THAP domain containing 3
chr19_-_45584769 1.08 ENST00000263275.5
outer mitochondrial membrane lipid metabolism regulator OPA3
chr7_-_124929801 1.07 ENST00000653241.1
ENST00000664366.1
ENST00000446993.6
ENST00000654766.1
ENST00000357628.8
ENST00000609702.5
protection of telomeres 1
chr16_+_19067893 1.07 ENST00000544894.6
ENST00000561858.5
coenzyme Q7, hydroxylase
chr4_-_2009164 1.07 ENST00000542778.5
negative elongation factor complex member A
chr5_-_138875290 1.06 ENST00000521094.2
ENST00000274711.7
leucine rich repeat transmembrane neuronal 2
chr1_+_28328994 1.06 ENST00000373842.9
ENST00000398997.2
mediator complex subunit 18
chr19_-_43596123 1.05 ENST00000422989.6
ENST00000598324.1
immunity related GTPase Q
chr7_-_124929938 1.04 ENST00000668382.1
ENST00000655761.1
ENST00000393329.5
protection of telomeres 1
chr11_-_68271896 1.04 ENST00000533310.5
ENST00000304271.11
ENST00000527280.1
chromosome 11 open reading frame 24
chr3_-_119463606 1.03 ENST00000319172.10
ENST00000491685.5
ENST00000461654.1
transmembrane protein 39A
chr19_+_43596575 1.03 ENST00000528387.5
ENST00000529930.1
ENST00000336564.5
ENST00000607544.1
zinc finger protein 576
serine/arginine repetitive matrix 5
chr1_+_168178916 1.02 ENST00000367833.7
TOR signaling pathway regulator
chrX_-_7927375 1.01 ENST00000381042.9
patatin like phospholipase domain containing 4
chr2_-_219309350 1.00 ENST00000295718.7
protein tyrosine phosphatase receptor type N
chr7_+_99408958 1.00 ENST00000222969.10
BUD31 homolog
chr2_+_3658193 0.96 ENST00000252505.4
allantoicase
chr9_-_96619378 0.96 ENST00000375240.7
ENST00000463569.5
cell division cycle 14B
chr16_+_19067639 0.96 ENST00000568985.5
ENST00000566110.5
coenzyme Q7, hydroxylase
chr19_-_50333504 0.94 ENST00000474951.1
potassium voltage-gated channel subfamily C member 3
chr2_-_113756604 0.93 ENST00000409342.1
solute carrier family 35 member F5
chr6_-_106325735 0.93 ENST00000635758.2
ENST00000369076.8
ENST00000636437.1
autophagy related 5
chr12_+_6904962 0.93 ENST00000415834.5
ENST00000436789.5
leucine rich repeat containing 23
chr19_+_43596388 0.90 ENST00000391965.6
ENST00000525771.1
zinc finger protein 576
chr6_-_106325416 0.88 ENST00000343245.7
autophagy related 5
chr7_+_100612102 0.87 ENST00000223054.8
motile sperm domain containing 3
chr8_-_81842192 0.87 ENST00000353788.8
ENST00000520618.5
ENST00000518183.5
ENST00000396330.6
ENST00000519119.5
sorting nexin 16
chr16_+_56191728 0.86 ENST00000638705.1
ENST00000262494.12
G protein subunit alpha o1
chr11_-_3797490 0.85 ENST00000397004.8
ENST00000397007.8
ENST00000532475.1
ENST00000324932.12
nucleoporin 98 and 96 precursor
chr6_+_27815010 0.84 ENST00000621112.2
H2B clustered histone 14
chr6_-_56954747 0.82 ENST00000680361.1
dystonin

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.1 GO:0071373 cellular response to luteinizing hormone stimulus(GO:0071373)
2.1 12.7 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
2.0 6.1 GO:1901491 axial mesoderm morphogenesis(GO:0048319) negative regulation of lymphangiogenesis(GO:1901491)
1.9 5.7 GO:0009386 translational attenuation(GO:0009386)
1.9 5.6 GO:2000847 negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
1.6 4.8 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
1.5 12.0 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
1.4 6.9 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
1.3 10.7 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
1.3 4.0 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
1.2 5.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
1.1 5.5 GO:0030035 microspike assembly(GO:0030035)
1.1 3.2 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
1.1 6.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.8 2.5 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899)
0.8 3.3 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.8 5.3 GO:0060701 negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
0.7 2.2 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
0.7 2.8 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.7 14.1 GO:0000022 mitotic spindle elongation(GO:0000022)
0.7 2.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.7 2.8 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.7 2.1 GO:0051231 spindle elongation(GO:0051231)
0.6 1.9 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.6 2.4 GO:0003290 atrial septum secundum morphogenesis(GO:0003290)
0.6 4.8 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.6 5.5 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.5 4.8 GO:0051026 chiasma assembly(GO:0051026)
0.5 4.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.5 3.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.5 2.4 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.5 6.7 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.5 1.9 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.4 1.7 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.4 1.2 GO:0006288 base-excision repair, DNA ligation(GO:0006288)
0.4 18.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.4 3.6 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.4 16.1 GO:0097284 hepatocyte apoptotic process(GO:0097284)
0.4 0.8 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.4 2.6 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.4 8.1 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.4 27.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.4 4.6 GO:0000050 urea cycle(GO:0000050)
0.3 2.4 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.3 3.1 GO:0000012 single strand break repair(GO:0000012)
0.3 1.0 GO:0043605 cellular amide catabolic process(GO:0043605)
0.3 1.6 GO:0061000 negative regulation of dendritic spine development(GO:0061000)
0.3 5.8 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.3 2.6 GO:0045054 constitutive secretory pathway(GO:0045054)
0.3 6.5 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.3 4.9 GO:0031268 pseudopodium organization(GO:0031268)
0.3 2.2 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.2 1.0 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.2 3.6 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.2 5.5 GO:0006206 pyrimidine nucleobase metabolic process(GO:0006206)
0.2 4.2 GO:0072520 seminiferous tubule development(GO:0072520)
0.2 1.7 GO:0061709 reticulophagy(GO:0061709)
0.2 14.5 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.2 0.8 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.2 1.4 GO:0043985 histone H4-R3 methylation(GO:0043985) negative regulation of megakaryocyte differentiation(GO:0045653) positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.2 3.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.2 3.5 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 1.5 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.2 10.3 GO:0031648 protein destabilization(GO:0031648)
0.2 4.8 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.2 6.3 GO:0031055 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.2 5.9 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.2 0.5 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.2 7.0 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.2 2.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.2 1.0 GO:0051012 microtubule sliding(GO:0051012)
0.2 0.5 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 2.0 GO:0006089 lactate metabolic process(GO:0006089)
0.2 1.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.2 1.8 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.2 2.6 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.2 0.6 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.2 2.6 GO:0003322 pancreatic A cell development(GO:0003322)
0.1 0.6 GO:0061668 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 0.6 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.1 1.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 2.7 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.1 0.7 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 2.5 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.1 5.3 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 1.8 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 3.0 GO:0002003 angiotensin maturation(GO:0002003)
0.1 3.0 GO:0060972 left/right pattern formation(GO:0060972)
0.1 3.5 GO:0006379 mRNA cleavage(GO:0006379)
0.1 1.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.1 1.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.4 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 1.0 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.1 4.1 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 0.7 GO:0031860 regulation of mitotic recombination(GO:0000019) telomeric 3' overhang formation(GO:0031860) negative regulation of telomere capping(GO:1904354)
0.1 3.9 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.1 3.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506) negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.8 GO:0008090 retrograde axonal transport(GO:0008090)
0.1 0.6 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
0.1 0.8 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.1 11.5 GO:0021987 cerebral cortex development(GO:0021987)
0.1 0.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.6 GO:0006983 ER overload response(GO:0006983)
0.1 0.8 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585) membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.1 3.7 GO:0021762 substantia nigra development(GO:0021762)
0.1 0.5 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 1.1 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.1 0.7 GO:0001842 neural fold formation(GO:0001842)
0.1 1.5 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 3.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 3.1 GO:0010107 potassium ion import(GO:0010107)
0.1 0.7 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.1 1.8 GO:0016578 histone deubiquitination(GO:0016578)
0.1 1.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.1 1.7 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.4 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.6 GO:0051775 response to redox state(GO:0051775)
0.0 1.6 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 1.3 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 1.7 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 1.0 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 2.6 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 1.2 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.3 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.5 GO:0010447 hyperosmotic response(GO:0006972) response to acidic pH(GO:0010447)
0.0 5.1 GO:0006310 DNA recombination(GO:0006310)
0.0 3.9 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 2.5 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.2 GO:0021542 dentate gyrus development(GO:0021542)
0.0 1.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 1.1 GO:0019915 lipid storage(GO:0019915)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.5 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 1.1 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 1.3 GO:0007286 spermatid development(GO:0007286)
0.0 0.3 GO:0008045 motor neuron axon guidance(GO:0008045)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 7.0 GO:0071148 TEAD-1-YAP complex(GO:0071148)
1.8 5.5 GO:0044393 microspike(GO:0044393)
1.8 19.9 GO:0033588 Elongator holoenzyme complex(GO:0033588)
1.6 4.8 GO:0031262 Ndc80 complex(GO:0031262)
1.4 5.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
1.4 8.1 GO:0001940 male pronucleus(GO:0001940)
1.2 12.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.8 8.1 GO:0000439 core TFIIH complex(GO:0000439)
0.8 10.8 GO:0070938 contractile ring(GO:0070938)
0.8 3.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.8 5.3 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.6 3.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.6 3.2 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.6 1.8 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.6 1.7 GO:0098536 deuterosome(GO:0098536)
0.5 13.0 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.5 14.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.4 3.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.4 11.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.4 16.1 GO:0034451 centriolar satellite(GO:0034451)
0.4 4.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.4 14.2 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.4 2.5 GO:0032021 NELF complex(GO:0032021)
0.3 2.4 GO:0045179 apical cortex(GO:0045179)
0.3 5.9 GO:0036020 endolysosome membrane(GO:0036020)
0.3 4.8 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.3 2.1 GO:0070187 telosome(GO:0070187)
0.2 1.0 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.2 3.0 GO:0044292 dendrite terminus(GO:0044292)
0.2 4.0 GO:1990909 Wnt signalosome(GO:1990909)
0.2 13.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 1.1 GO:0070847 core mediator complex(GO:0070847)
0.2 2.6 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 3.6 GO:0097440 apical dendrite(GO:0097440)
0.2 5.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.2 0.8 GO:0031673 H zone(GO:0031673)
0.2 6.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 2.5 GO:0042583 chromaffin granule(GO:0042583)
0.2 2.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 1.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1 5.6 GO:0000795 synaptonemal complex(GO:0000795)
0.1 6.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.6 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1 0.7 GO:0033061 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 1.5 GO:0000124 SAGA complex(GO:0000124)
0.1 1.0 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 8.2 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 2.6 GO:0031143 pseudopodium(GO:0031143)
0.1 2.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 1.4 GO:0034709 methylosome(GO:0034709)
0.1 8.5 GO:0005811 lipid particle(GO:0005811)
0.1 0.7 GO:0030870 Mre11 complex(GO:0030870)
0.1 1.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.1 0.5 GO:0070652 HAUS complex(GO:0070652)
0.1 4.8 GO:0072686 mitotic spindle(GO:0072686)
0.0 4.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 3.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.9 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 2.5 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 3.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.5 GO:0005686 U2 snRNP(GO:0005686) U12-type spliceosomal complex(GO:0005689)
0.0 15.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 1.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 2.7 GO:0014704 intercalated disc(GO:0014704)
0.0 4.6 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.2 GO:0005876 spindle microtubule(GO:0005876)
0.0 4.0 GO:0005923 bicellular tight junction(GO:0005923)
0.0 5.8 GO:0001726 ruffle(GO:0001726)
0.0 17.1 GO:0005815 microtubule organizing center(GO:0005815)
0.0 0.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.6 GO:0042627 chylomicron(GO:0042627)
0.0 3.1 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 2.0 GO:0031514 motile cilium(GO:0031514)
0.0 3.7 GO:0043209 myelin sheath(GO:0043209)
0.0 2.2 GO:0043679 axon terminus(GO:0043679)
0.0 1.4 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.8 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 2.7 GO:0005743 mitochondrial inner membrane(GO:0005743)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 12.0 GO:0000035 acyl binding(GO:0000035)
3.2 12.7 GO:0043515 kinetochore binding(GO:0043515)
1.4 5.5 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
1.0 3.1 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
0.9 2.8 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.8 6.3 GO:0004111 creatine kinase activity(GO:0004111)
0.8 5.3 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.7 2.1 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.6 3.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.6 2.4 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.6 16.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.6 3.9 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.5 1.5 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.5 4.5 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.4 6.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.4 7.0 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.4 8.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.4 5.5 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.3 8.0 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.3 2.4 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.3 4.2 GO:0031386 protein tag(GO:0031386)
0.3 5.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.3 2.0 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
0.3 7.5 GO:0031489 myosin V binding(GO:0031489)
0.3 2.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.3 6.5 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.3 3.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.3 13.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 5.9 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.3 1.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 6.1 GO:0005003 ephrin receptor activity(GO:0005003)
0.2 1.4 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.2 5.8 GO:0048156 tau protein binding(GO:0048156)
0.2 5.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 5.8 GO:0000400 four-way junction DNA binding(GO:0000400)
0.2 4.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 3.5 GO:0031996 thioesterase binding(GO:0031996)
0.2 2.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.2 1.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.2 14.4 GO:0019843 rRNA binding(GO:0019843)
0.2 2.8 GO:0048018 receptor agonist activity(GO:0048018)
0.2 10.3 GO:0019894 kinesin binding(GO:0019894)
0.2 3.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 7.2 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 5.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 8.1 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.1 1.6 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 2.1 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.1 4.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.6 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 3.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 4.0 GO:0005109 frizzled binding(GO:0005109)
0.1 1.6 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.1 1.8 GO:0043495 protein anchor(GO:0043495)
0.1 0.7 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.1 4.8 GO:0043531 ADP binding(GO:0043531)
0.1 2.2 GO:0030507 spectrin binding(GO:0030507)
0.1 1.2 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 15.1 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.1 0.2 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.1 0.8 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.1 0.6 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 3.7 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 1.5 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 1.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.8 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 12.3 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 0.7 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 2.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 7.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.6 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
0.0 0.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 3.9 GO:0051213 dioxygenase activity(GO:0051213)
0.0 7.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 5.5 GO:0008144 drug binding(GO:0008144)
0.0 3.5 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 3.5 GO:0008565 protein transporter activity(GO:0008565)
0.0 2.6 GO:0046332 SMAD binding(GO:0046332)
0.0 8.8 GO:0045296 cadherin binding(GO:0045296)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 1.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.7 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 1.1 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 1.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 2.5 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 8.0 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.3 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.1 GO:0016298 lipase activity(GO:0016298)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 29.8 PID PLK1 PATHWAY PLK1 signaling events
0.4 8.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 4.0 PID IL5 PATHWAY IL5-mediated signaling events
0.2 8.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 7.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.2 9.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 6.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.1 4.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 3.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 4.8 PID RAS PATHWAY Regulation of Ras family activation
0.1 8.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 1.6 PID S1P S1P4 PATHWAY S1P4 pathway
0.1 3.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 4.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 5.0 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 5.5 PID E2F PATHWAY E2F transcription factor network
0.0 0.6 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.8 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.2 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 2.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.8 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 11.0 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.4 5.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.3 8.1 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3 5.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.3 8.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.3 6.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.3 2.1 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.2 7.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.2 5.9 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 1.8 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 5.5 REACTOME KINESINS Genes involved in Kinesins
0.2 7.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 3.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 3.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.2 5.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 13.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 2.4 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 7.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 7.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 2.0 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 2.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 2.0 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 1.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.1 1.6 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 4.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 2.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.5 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 2.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 1.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.8 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 7.4 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.9 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 2.4 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 4.0 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.9 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 1.5 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 1.2 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.5 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.7 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements