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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for AUAAAGU

Z-value: 4.91

Motif logo

miRNA associated with seed AUAAAGU

NamemiRBASE accession
MIMAT0000433
MIMAT0022300

Activity profile of AUAAAGU motif

Sorted Z-values of AUAAAGU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AUAAAGU

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_+_96662214 13.29 ENST00000395812.6
calpastatin
chr7_+_26201705 12.96 ENST00000396386.7
ENST00000456948.5
ENST00000409747.5
chromobox 3
chr9_+_36572854 12.59 ENST00000543751.5
ENST00000536860.5
ENST00000541717.4
ENST00000536329.5
ENST00000536987.5
ENST00000298048.7
ENST00000495529.5
ENST00000545008.5
maternal embryonic leucine zipper kinase
chr1_-_67430412 11.71 ENST00000370994.8
SERPINE1 mRNA binding protein 1
chr13_+_75549734 10.54 ENST00000563635.5
ENST00000377595.8
novel transcript
ubiquitin C-terminal hydrolase L3
chr1_+_115641945 9.82 ENST00000355485.7
ENST00000369510.8
VANGL planar cell polarity protein 1
chr17_+_59707636 9.25 ENST00000262291.9
ENST00000587945.1
ENST00000589823.6
ENST00000592106.5
ENST00000591315.5
vacuole membrane protein 1
chr15_+_52019206 9.17 ENST00000681888.1
ENST00000261845.7
ENST00000680066.1
ENST00000680777.1
ENST00000680652.1
mitogen-activated protein kinase 6
chrX_-_20266834 9.14 ENST00000379565.9
ribosomal protein S6 kinase A3
chr2_+_113890039 9.10 ENST00000443297.5
ENST00000263238.7
ENST00000415792.5
actin related protein 3
chr7_+_107891135 8.99 ENST00000639772.1
ENST00000440410.5
ENST00000437604.6
ENST00000205402.10
dihydrolipoamide dehydrogenase
chr12_-_102120065 8.59 ENST00000552283.6
ENST00000551744.2
nucleoporin 37
chr3_-_72446623 8.51 ENST00000477973.4
RING1 and YY1 binding protein
chr2_-_152717966 8.25 ENST00000410080.8
pre-mRNA processing factor 40 homolog A
chr16_-_47143934 8.19 ENST00000562435.6
neuropilin and tolloid like 2
chr19_+_38647614 7.81 ENST00000252699.7
ENST00000424234.7
ENST00000440400.2
actinin alpha 4
chr3_+_150603279 7.66 ENST00000615547.4
ENST00000477889.5
ENST00000471696.6
ENST00000485923.1
selenoprotein T
chr10_+_3067496 7.36 ENST00000381125.9
phosphofructokinase, platelet
chr15_+_76931704 7.16 ENST00000320963.9
ENST00000394885.8
ENST00000394883.3
reticulocalbin 2
chr22_+_38201932 7.06 ENST00000538999.1
ENST00000538320.5
ENST00000338483.7
ENST00000441709.1
MAF bZIP transcription factor F
chr8_-_102655707 6.91 ENST00000285407.11
Kruppel like factor 10
chr2_+_180980566 6.90 ENST00000410062.9
ubiquitin conjugating enzyme E2 E3
chr1_-_205750167 6.89 ENST00000367142.5
nuclear casein kinase and cyclin dependent kinase substrate 1
chr1_+_111619751 6.80 ENST00000433097.5
ENST00000369709.3
RAP1A, member of RAS oncogene family
chr19_-_1568301 6.78 ENST00000402693.5
mex-3 RNA binding family member D
chr2_+_99337364 6.52 ENST00000617677.1
ENST00000289371.11
eukaryotic translation initiation factor 5B
chr11_+_93784272 6.48 ENST00000251871.9
ENST00000639724.1
mediator complex subunit 17
chr17_-_64506281 6.12 ENST00000225792.10
ENST00000585060.5
DEAD-box helicase 5
chr10_+_87863595 6.09 ENST00000371953.8
phosphatase and tensin homolog
chr2_-_25878445 5.89 ENST00000336112.9
ENST00000435504.9
ASXL transcriptional regulator 2
chr5_+_32585549 5.88 ENST00000265073.9
ENST00000515355.5
ENST00000502897.5
ENST00000510442.1
SUB1 regulator of transcription
chr15_+_56918612 5.87 ENST00000438423.6
ENST00000267811.9
ENST00000333725.10
ENST00000559609.5
transcription factor 12
chr10_+_28677487 5.75 ENST00000375533.6
BMP and activin membrane bound inhibitor
chr14_+_100239121 5.75 ENST00000262238.10
YY1 transcription factor
chr3_-_79019444 5.72 ENST00000618833.4
ENST00000436010.6
ENST00000618846.4
roundabout guidance receptor 1
chr2_+_200811882 5.46 ENST00000409600.6
basic leucine zipper and W2 domains 1
chr12_-_117190456 5.29 ENST00000330622.9
ENST00000622495.5
ENST00000427718.6
F-box protein 21
chr19_-_12957198 5.27 ENST00000316939.3
GADD45G interacting protein 1
chr7_-_23470469 5.22 ENST00000258729.8
insulin like growth factor 2 mRNA binding protein 3
chr6_-_24719146 5.16 ENST00000378119.9
chromosome 6 open reading frame 62
chr5_+_163505564 4.90 ENST00000421814.6
ENST00000518095.5
ENST00000321757.11
methionine adenosyltransferase 2B
chr3_-_160565560 4.79 ENST00000334256.9
ENST00000676866.1
ENST00000469804.1
karyopherin subunit alpha 4
chr10_+_103967105 4.71 ENST00000369755.4
ENST00000335753.8
STE20 like kinase
chr8_-_102864155 4.63 ENST00000682725.1
ENST00000337198.10
ENST00000681985.1
ENST00000684566.1
ENST00000683787.1
ENST00000682014.1
ENST00000682969.1
ENST00000684721.1
ENST00000347770.8
antizyme inhibitor 1
chr16_+_69187125 4.61 ENST00000336278.8
syntrophin beta 2
chr6_-_85642922 4.47 ENST00000616122.5
ENST00000678618.1
ENST00000678816.1
ENST00000676630.1
ENST00000678589.1
ENST00000678878.1
ENST00000676542.1
ENST00000355238.11
ENST00000678899.1
synaptotagmin binding cytoplasmic RNA interacting protein
chr1_-_224434750 4.38 ENST00000414423.9
ENST00000678917.1
ENST00000678555.1
ENST00000678307.1
WD repeat domain 26
chr1_-_64966488 4.32 ENST00000342505.5
ENST00000673254.1
Janus kinase 1
chrX_-_110318062 4.30 ENST00000372059.6
ENST00000262844.10
AMMECR nuclear protein 1
chr17_-_42017410 4.29 ENST00000316603.12
ENST00000674175.1
ENST00000674233.1
ENST00000457167.9
ENST00000674306.1
DnaJ heat shock protein family (Hsp40) member C7
chr15_-_77071099 4.25 ENST00000267970.9
ENST00000346495.6
ENST00000424443.7
ENST00000561277.5
tetraspanin 3
chr17_-_48545077 4.21 ENST00000330070.6
homeobox B2
chr2_-_160493799 4.15 ENST00000348849.8
RNA binding motif single stranded interacting protein 1
chr13_+_97953652 4.11 ENST00000460070.6
ENST00000481455.6
ENST00000261574.10
ENST00000651721.2
ENST00000493281.6
ENST00000463157.6
ENST00000471898.5
ENST00000489058.6
ENST00000481689.6
importin 5
chr14_+_104753120 3.85 ENST00000535554.4
ENST00000329967.11
ENST00000347067.9
ENST00000553810.5
SIVA1 apoptosis inducing factor
chr5_+_179732811 3.79 ENST00000292599.4
mastermind like transcriptional coactivator 1
chr17_+_30477362 3.73 ENST00000225724.9
ENST00000451249.7
ENST00000467337.6
ENST00000581721.5
ENST00000414833.2
golgi SNAP receptor complex member 1
chr3_+_30606574 3.68 ENST00000295754.10
ENST00000359013.4
transforming growth factor beta receptor 2
chr7_+_157138912 3.42 ENST00000611269.4
ENST00000348165.10
ubiquitin protein ligase E3C
chr21_-_17612842 3.39 ENST00000339775.10
ENST00000348354.7
BTG anti-proliferation factor 3
chr6_-_79078247 3.37 ENST00000275034.5
pleckstrin homology domain interacting protein
chr4_-_25862979 3.33 ENST00000399878.8
SEL1L family member 3
chr18_-_21111778 3.24 ENST00000399799.3
Rho associated coiled-coil containing protein kinase 1
chr17_+_48908397 3.21 ENST00000360943.10
ubiquitin conjugating enzyme E2 Z
chr3_+_52198086 3.13 ENST00000469224.5
ENST00000394965.6
5'-aminolevulinate synthase 1
chr15_-_37098281 3.12 ENST00000559085.5
ENST00000397624.7
Meis homeobox 2
chr5_+_151771884 3.06 ENST00000627077.2
ENST00000678976.1
ENST00000677408.1
ENST00000678070.1
ENST00000678964.1
ENST00000678925.1
ENST00000394123.7
ENST00000522761.6
ENST00000676827.1
G3BP stress granule assembly factor 1
chr5_-_115544734 3.04 ENST00000274457.5
fem-1 homolog C
chrX_-_134915232 3.03 ENST00000370783.8
motile sperm domain containing 1
chr14_-_34630109 3.00 ENST00000396526.7
sorting nexin 6
chr12_+_64404338 2.98 ENST00000332707.10
exportin for tRNA
chr6_-_36547400 2.98 ENST00000229812.8
serine/threonine kinase 38
chr17_-_75182949 2.98 ENST00000314523.7
ENST00000420826.7
small ubiquitin like modifier 2
chr8_-_129939694 2.98 ENST00000522250.5
ENST00000522941.5
ENST00000522746.5
ENST00000520204.5
ENST00000519070.5
ENST00000520254.5
ENST00000519824.6
CYFIP related Rac1 interactor B
chr6_-_89352706 2.96 ENST00000435041.3
ubiquitin conjugating enzyme E2 J1
chr2_-_183038405 2.94 ENST00000361354.9
NCK associated protein 1
chr10_+_80454148 2.87 ENST00000429989.7
tetraspanin 14
chr16_+_24539536 2.85 ENST00000568015.5
ENST00000319715.10
RB binding protein 6, ubiquitin ligase
chr3_+_107522936 2.84 ENST00000415149.6
ENST00000402543.5
ENST00000325805.13
ENST00000427402.5
BBX high mobility group box domain containing
chr2_-_241272812 2.80 ENST00000427007.5
ENST00000458564.5
ENST00000452065.5
ENST00000427183.6
ENST00000426343.5
ENST00000422080.5
ENST00000449504.5
ENST00000449864.5
ENST00000391975.5
high density lipoprotein binding protein
chr1_-_52552994 2.62 ENST00000355809.4
ENST00000528642.5
ENST00000470626.1
ENST00000257177.9
ENST00000371544.7
terminal uridylyl transferase 4
chr12_-_26125023 2.58 ENST00000242728.5
basic helix-loop-helix family member e41
chr15_+_65869535 2.54 ENST00000569896.1
RAB11A, member RAS oncogene family
chr3_+_105366877 2.53 ENST00000306107.9
activated leukocyte cell adhesion molecule
chr1_+_86914616 2.45 ENST00000370550.10
ENST00000370551.8
heparan sulfate 2-O-sulfotransferase 1
chr2_+_236569817 2.34 ENST00000272928.4
atypical chemokine receptor 3
chr2_+_134120169 2.33 ENST00000409645.5
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase
chr12_-_92145838 2.33 ENST00000256015.5
BTG anti-proliferation factor 1
chr8_-_52714414 2.30 ENST00000435644.6
ENST00000518710.5
ENST00000025008.10
ENST00000517963.1
RB1 inducible coiled-coil 1
chr1_+_26695993 2.30 ENST00000324856.13
ENST00000637465.1
AT-rich interaction domain 1A
chr15_-_59689283 2.29 ENST00000607373.6
ENST00000612191.4
ENST00000267859.8
BCL2 interacting protein 2
chr18_+_3247778 2.27 ENST00000217652.8
ENST00000578611.5
ENST00000583449.1
myosin light chain 12A
chr22_-_38272996 2.27 ENST00000361906.8
transmembrane protein 184B
chr8_+_97644164 2.25 ENST00000336273.8
metadherin
chr5_+_10353668 2.22 ENST00000274140.10
ENST00000449913.6
ENST00000503788.5
membrane associated ring-CH-type finger 6
chr12_-_75511594 2.19 ENST00000438169.6
ENST00000229214.9
KRR1 small subunit processome component homolog
chr17_+_59565598 2.15 ENST00000251241.9
ENST00000425628.7
ENST00000584385.5
ENST00000580030.1
DEAH-box helicase 40
chr14_-_23071538 2.14 ENST00000555566.1
ENST00000338631.10
ENST00000557515.5
ENST00000397341.7
apoptotic chromatin condensation inducer 1
chr15_-_41972504 2.12 ENST00000220325.9
EH domain containing 4
chr1_+_15847698 2.12 ENST00000375759.8
spen family transcriptional repressor
chr21_-_26845402 2.03 ENST00000284984.8
ENST00000676955.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr1_-_31065671 2.03 ENST00000440538.6
ENST00000424085.6
ENST00000257075.9
ENST00000373747.7
ENST00000426105.7
ENST00000525843.5
ENST00000373742.6
pumilio RNA binding family member 1
chr3_-_52679713 2.00 ENST00000296302.11
ENST00000356770.8
ENST00000337303.8
ENST00000409057.5
ENST00000410007.5
ENST00000409114.7
ENST00000409767.5
ENST00000423351.5
polybromo 1
chr20_+_45890236 1.99 ENST00000372484.8
ENST00000677394.1
cathepsin A
chr4_+_56907876 1.97 ENST00000640168.2
ENST00000309042.12
RE1 silencing transcription factor
chr8_+_105318428 1.94 ENST00000407775.7
zinc finger protein, FOG family member 2
chr19_+_34254543 1.94 ENST00000588470.5
ENST00000299505.8
ENST00000589583.5
granule associated Rac and RHOG effector 1
chr4_+_17614630 1.93 ENST00000237380.12
mediator complex subunit 28
chr4_+_146175702 1.89 ENST00000296581.11
ENST00000649747.1
ENST00000502781.5
LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
chr7_-_27174274 1.88 ENST00000283921.5
homeobox A10
chr2_+_108719473 1.82 ENST00000283195.11
RAN binding protein 2
chr11_-_6612141 1.81 ENST00000527248.2
ENST00000299424.9
TATA-box binding protein associated factor 10
chr8_-_104588998 1.81 ENST00000424843.6
LDL receptor related protein 12
chr8_+_63168597 1.79 ENST00000539294.6
ENST00000621957.4
ENST00000517371.5
ENST00000621413.4
ENST00000612880.4
YTH N6-methyladenosine RNA binding protein 3
chr3_+_43690880 1.77 ENST00000458276.7
abhydrolase domain containing 5, lysophosphatidic acid acyltransferase
chr22_-_49824804 1.76 ENST00000216267.12
ENST00000457780.3
bromodomain containing 1
chrX_+_147911943 1.71 ENST00000621453.4
ENST00000218200.12
ENST00000370471.7
ENST00000440235.6
ENST00000370477.5
ENST00000621987.4
FMRP translational regulator 1
chr17_+_32142454 1.70 ENST00000333942.10
ENST00000358365.7
ENST00000545287.7
ras homolog family member T1
chr4_-_73258785 1.69 ENST00000639793.1
ENST00000358602.9
ENST00000330838.10
ENST00000561029.1
ankyrin repeat domain 17
chr1_-_244864560 1.67 ENST00000444376.7
heterogeneous nuclear ribonucleoprotein U
chr10_+_86756580 1.65 ENST00000372037.8
bone morphogenetic protein receptor type 1A
chr17_+_18781155 1.63 ENST00000574226.5
ENST00000575261.5
ENST00000307767.13
trans-golgi network vesicle protein 23 homolog B
chr10_+_68332055 1.59 ENST00000265866.12
heterogeneous nuclear ribonucleoprotein H3
chr18_+_22933819 1.58 ENST00000399722.6
ENST00000399725.6
ENST00000399721.6
RB binding protein 8, endonuclease
chr19_+_10871516 1.57 ENST00000327064.9
ENST00000588947.5
coactivator associated arginine methyltransferase 1
chr5_+_103120149 1.57 ENST00000515845.5
ENST00000321521.13
ENST00000507921.5
diphosphoinositol pentakisphosphate kinase 2
chr2_-_37671633 1.56 ENST00000295324.4
CDC42 effector protein 3
chr12_-_76031588 1.55 ENST00000602540.5
pleckstrin homology like domain family A member 1
chr3_+_150408314 1.54 ENST00000361875.7
TSC22 domain family member 2
chr1_+_203626775 1.51 ENST00000367218.7
ATPase plasma membrane Ca2+ transporting 4
chr1_-_53328053 1.49 ENST00000371454.6
ENST00000667377.1
ENST00000306052.12
ENST00000668448.1
LDL receptor related protein 8
chr4_-_70839873 1.44 ENST00000545193.5
ENST00000254799.11
G-rich RNA sequence binding factor 1
chr7_-_88220025 1.43 ENST00000419179.5
ENST00000265729.7
sorcin
chr18_+_2655693 1.38 ENST00000320876.11
structural maintenance of chromosomes flexible hinge domain containing 1
chr13_-_23375431 1.38 ENST00000683270.1
ENST00000684163.1
ENST00000402364.1
ENST00000683367.1
sacsin molecular chaperone
chr6_+_15246054 1.37 ENST00000341776.7
jumonji and AT-rich interaction domain containing 2
chr10_+_69124152 1.36 ENST00000395098.5
ENST00000263559.11
VPS26, retromer complex component A
chr11_-_30586344 1.36 ENST00000358117.10
metallophosphoesterase domain containing 2
chr21_-_41926680 1.34 ENST00000329623.11
C2 calcium dependent domain containing 2
chrX_-_41922992 1.32 ENST00000646120.2
ENST00000421587.8
ENST00000644770.1
ENST00000645566.1
ENST00000378166.9
ENST00000378158.6
ENST00000644219.1
ENST00000442742.7
ENST00000644347.1
calcium/calmodulin dependent serine protein kinase
chr8_+_30156359 1.29 ENST00000520829.5
ENST00000221114.8
dynactin subunit 6
chr16_+_53054973 1.28 ENST00000447540.6
ENST00000615216.4
ENST00000566029.5
chromodomain helicase DNA binding protein 9
chr2_+_186590022 1.22 ENST00000261023.8
ENST00000374907.7
integrin subunit alpha V
chr13_+_40789548 1.20 ENST00000338625.9
solute carrier family 25 member 15
chr7_-_92246045 1.19 ENST00000394507.5
ENST00000458177.6
ENST00000340022.6
ENST00000444960.5
KRIT1 ankyrin repeat containing
chr12_+_62260338 1.17 ENST00000353364.7
ENST00000549523.5
ubiquitin specific peptidase 15
chr2_+_119759875 1.16 ENST00000263708.7
protein tyrosine phosphatase non-receptor type 4
chr6_-_111483190 1.16 ENST00000368802.8
REV3 like, DNA directed polymerase zeta catalytic subunit
chr1_-_26890237 1.14 ENST00000431781.2
ENST00000374135.9
GPN-loop GTPase 2
chr11_+_20599602 1.13 ENST00000525748.6
solute carrier family 6 member 5
chr3_+_15206179 1.12 ENST00000253693.7
calpain 7
chrX_+_106693838 1.12 ENST00000324342.7
ring finger protein 128
chr5_-_81751103 1.11 ENST00000514493.5
ENST00000320672.8
ENST00000615665.4
single stranded DNA binding protein 2
chr20_+_58309704 1.06 ENST00000244040.4
RAB22A, member RAS oncogene family
chr18_-_47930630 1.04 ENST00000262160.11
SMAD family member 2
chr4_+_176319942 1.04 ENST00000503362.2
signal peptidase complex subunit 3
chr20_-_63969890 1.02 ENST00000369888.6
zinc finger protein 512B
chr7_-_151057880 1.02 ENST00000485972.6
cyclin dependent kinase 5
chr1_+_161766309 1.00 ENST00000679853.1
ENST00000681492.1
ENST00000679886.1
ENST00000367942.4
ENST00000680462.1
ENST00000680633.1
ENST00000681912.1
activating transcription factor 6
chr9_+_125747345 1.00 ENST00000342287.9
ENST00000373489.10
ENST00000373487.8
PBX homeobox 3
chr9_+_116687295 0.99 ENST00000450136.2
ENST00000373983.2
ENST00000411410.1
tripartite motif containing 32
chr13_+_32586443 0.99 ENST00000315596.15
PDS5 cohesin associated factor B
chr20_-_49188360 0.98 ENST00000371828.7
ENST00000340954.11
ENST00000347458.9
ENST00000360426.8
ENST00000371792.5
ENST00000371802.5
ENST00000437404.2
staufen double-stranded RNA binding protein 1
chr1_+_212035717 0.97 ENST00000366991.5
denticleless E3 ubiquitin protein ligase homolog
chrX_-_40097403 0.96 ENST00000397354.7
BCL6 corepressor
chr2_-_39437264 0.96 ENST00000263881.8
ENST00000341681.9
mitogen-activated protein kinase kinase kinase kinase 3
chr8_+_86342539 0.96 ENST00000517970.6
WW domain containing E3 ubiquitin protein ligase 1
chr3_-_125375249 0.95 ENST00000484491.5
ENST00000492394.5
ENST00000471196.1
ENST00000468369.5
ENST00000485866.5
ENST00000360647.9
zinc finger protein 148
chr6_-_16761447 0.92 ENST00000244769.8
ENST00000436367.6
ataxin 1
chr2_+_46542474 0.90 ENST00000238738.9
ras homolog family member Q
chr7_+_24573415 0.90 ENST00000409761.5
ENST00000222644.10
ENST00000396475.6
membrane palmitoylated protein 6
chr12_+_53454718 0.90 ENST00000552819.5
ENST00000455667.7
poly(rC) binding protein 2
chr3_+_57227714 0.88 ENST00000288266.8
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1
chr6_-_89412219 0.87 ENST00000369415.9
Ras related GTP binding D
chr21_-_26967057 0.83 ENST00000284987.6
ADAM metallopeptidase with thrombospondin type 1 motif 5
chr3_-_150546403 0.83 ENST00000239944.7
ENST00000491660.1
ENST00000487153.1
stress associated endoplasmic reticulum protein 1
chr14_-_99480831 0.82 ENST00000331768.10
ENST00000630307.2
SET domain containing 3, actin histidine methyltransferase
chr7_-_13989658 0.81 ENST00000430479.6
ENST00000433547.1
ENST00000405192.6
ETS variant transcription factor 1
chr8_-_23854796 0.81 ENST00000290271.7
stanniocalcin 1
chr15_+_49423233 0.80 ENST00000560270.1
ENST00000267843.9
ENST00000560979.1
fibroblast growth factor 7
chr6_+_4889992 0.80 ENST00000343762.5
chromodomain Y like
chr10_+_73998104 0.80 ENST00000372755.7
ENST00000211998.10
vinculin
chr13_-_37598750 0.79 ENST00000379743.8
ENST00000379742.4
ENST00000379749.8
ENST00000379747.9
ENST00000541179.5
ENST00000541481.5
periostin
chr1_+_93079264 0.78 ENST00000370298.9
ENST00000370303.4
metal response element binding transcription factor 2
chr6_+_137867414 0.76 ENST00000237289.8
ENST00000433680.1
TNF alpha induced protein 3
chr3_+_179148341 0.75 ENST00000263967.4
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr6_+_63572472 0.73 ENST00000370651.7
ENST00000626021.3
novel protein
protein tyrosine phosphatase 4A1
chr12_-_119877300 0.71 ENST00000392521.7
citron rho-interacting serine/threonine kinase
chr15_-_52569197 0.71 ENST00000563277.5
ENST00000566423.5
cAMP regulated phosphoprotein 19
chr11_-_95924067 0.70 ENST00000676027.1
ENST00000675489.1
ENST00000409459.5
ENST00000676261.1
ENST00000352297.11
ENST00000346299.10
ENST00000676272.1
ENST00000393223.8
ENST00000675022.1
ENST00000675362.1
ENST00000675174.1
ENST00000674989.1
ENST00000675848.1
ENST00000675652.1
ENST00000481642.6
myotubularin related protein 2
chr2_+_54456311 0.69 ENST00000615901.4
ENST00000356805.9
spectrin beta, non-erythrocytic 1
chr17_-_13601901 0.69 ENST00000284110.2
heparan sulfate-glucosamine 3-sulfotransferase 3A1
chr20_+_4686448 0.68 ENST00000379440.9
ENST00000424424.2
ENST00000457586.2
prion protein
chr2_-_27409523 0.68 ENST00000344034.5
protein phosphatase, Mg2+/Mn2+ dependent 1G
chr1_+_113929600 0.67 ENST00000369558.5
ENST00000369561.8
homeodomain interacting protein kinase 1
chr10_+_110207587 0.65 ENST00000332674.9
ENST00000453116.5
MAX interactor 1, dimerization protein
chr19_+_531750 0.64 ENST00000215574.9
cell division cycle 34, ubiqiutin conjugating enzyme
chr10_-_60944132 0.63 ENST00000337910.10
Rho related BTB domain containing 1
chr4_-_101347471 0.62 ENST00000323055.10
ENST00000512215.5
protein phosphatase 3 catalytic subunit alpha
chr16_+_68085552 0.61 ENST00000329524.8
nuclear factor of activated T cells 3

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
3.0 9.0 GO:0009106 lipoate metabolic process(GO:0009106)
2.3 6.9 GO:0060382 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
1.7 6.8 GO:0097327 response to antineoplastic agent(GO:0097327)
1.5 4.6 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
1.5 6.1 GO:1903984 rhythmic synaptic transmission(GO:0060024) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
1.4 5.7 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
1.3 5.3 GO:0003186 tricuspid valve development(GO:0003175) tricuspid valve morphogenesis(GO:0003186)
1.3 7.8 GO:0048549 positive regulation of pinocytosis(GO:0048549)
1.3 3.8 GO:0003162 atrioventricular node development(GO:0003162)
1.2 4.9 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
1.0 4.1 GO:0021569 rhombomere 3 development(GO:0021569)
1.0 1.9 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.8 3.4 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.8 5.3 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.7 2.0 GO:2000797 amniotic stem cell differentiation(GO:0097086) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798)
0.6 7.7 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.6 2.5 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.6 13.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.6 1.7 GO:1901254 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.5 1.6 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
0.5 6.8 GO:0008298 intracellular mRNA localization(GO:0008298)
0.5 1.5 GO:2000282 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) regulation of cellular amino acid biosynthetic process(GO:2000282) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.5 5.9 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.5 4.3 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.5 2.3 GO:0030242 pexophagy(GO:0030242)
0.5 2.3 GO:0003408 optic cup formation involved in camera-type eye development(GO:0003408) maintenance of chromatin silencing(GO:0006344)
0.5 10.1 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.4 6.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.4 3.7 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.4 7.4 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.4 1.2 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.4 1.2 GO:0015822 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.4 1.1 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.4 1.1 GO:0036233 glycine import(GO:0036233)
0.4 3.0 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.4 2.9 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.3 1.0 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
0.3 1.7 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
0.3 6.1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.3 5.8 GO:0035413 positive regulation of catenin import into nucleus(GO:0035413)
0.3 5.7 GO:0010225 response to UV-C(GO:0010225)
0.3 2.9 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.3 10.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.3 9.1 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.3 1.1 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.3 7.1 GO:0007567 parturition(GO:0007567)
0.3 11.6 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.3 0.5 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.3 4.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.2 1.0 GO:0007386 compartment pattern specification(GO:0007386)
0.2 1.0 GO:0030047 actin modification(GO:0030047)
0.2 2.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.2 1.6 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.2 0.4 GO:0010040 response to iron(II) ion(GO:0010040)
0.2 2.0 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.2 1.9 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.2 1.5 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.2 1.4 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 0.8 GO:0060437 lung growth(GO:0060437)
0.2 2.0 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.2 1.0 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.2 1.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.2 0.8 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.2 0.7 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.2 6.1 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.2 8.9 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.2 2.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.2 2.8 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.2 0.9 GO:0071233 cellular response to leucine(GO:0071233)
0.2 0.7 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.2 0.5 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693) uterine wall breakdown(GO:0042704)
0.2 2.6 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.2 1.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 0.7 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
0.2 0.3 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.2 3.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.2 3.1 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.2 1.8 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.2 0.8 GO:0035926 chemokine (C-C motif) ligand 2 secretion(GO:0035926)
0.2 0.5 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.2 0.6 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.2 6.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 1.0 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 12.0 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.1 5.9 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.1 1.0 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1 8.2 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
0.1 2.0 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.4 GO:0071315 late nucleophagy(GO:0044805) cellular response to morphine(GO:0071315) cellular response to isoquinoline alkaloid(GO:0071317)
0.1 1.1 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 8.9 GO:0032465 regulation of cytokinesis(GO:0032465)
0.1 2.1 GO:0006907 pinocytosis(GO:0006907)
0.1 8.3 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 1.6 GO:0006020 inositol metabolic process(GO:0006020)
0.1 1.4 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 0.3 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.1 1.0 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.1 0.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.8 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 5.1 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 4.1 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 0.7 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.8 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 3.0 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.1 1.5 GO:0097264 self proteolysis(GO:0097264)
0.1 0.8 GO:0060536 cartilage morphogenesis(GO:0060536)
0.1 5.7 GO:0060071 Wnt signaling pathway, planar cell polarity pathway(GO:0060071)
0.1 0.6 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.1 14.1 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 2.0 GO:0060065 uterus development(GO:0060065)
0.1 2.0 GO:0016578 histone deubiquitination(GO:0016578)
0.1 15.5 GO:0006338 chromatin remodeling(GO:0006338)
0.1 1.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 4.1 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.1 0.7 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
0.1 0.2 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.1 3.4 GO:0032508 DNA duplex unwinding(GO:0032508)
0.1 1.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 2.3 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.9 GO:0002190 cap-independent translational initiation(GO:0002190) IRES-dependent translational initiation(GO:0002192) IRES-dependent viral translational initiation(GO:0075522)
0.1 1.8 GO:0035902 response to immobilization stress(GO:0035902)
0.1 1.0 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.5 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.0 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.1 0.9 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1 0.4 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 1.3 GO:0046710 GDP metabolic process(GO:0046710)
0.0 2.2 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.0 3.7 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.0 1.2 GO:2000352 negative regulation of endothelial cell apoptotic process(GO:2000352)
0.0 2.9 GO:0045638 negative regulation of myeloid cell differentiation(GO:0045638)
0.0 0.7 GO:0072577 endothelial cell apoptotic process(GO:0072577)
0.0 0.2 GO:0098904 regulation of AV node cell action potential(GO:0098904)
0.0 0.4 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.0 1.0 GO:0006465 signal peptide processing(GO:0006465)
0.0 1.2 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.0 2.1 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.0 0.6 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 2.7 GO:0070527 platelet aggregation(GO:0070527)
0.0 12.1 GO:0043687 post-translational protein modification(GO:0043687)
0.0 4.3 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.6 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 2.8 GO:0006024 aminoglycan biosynthetic process(GO:0006023) glycosaminoglycan biosynthetic process(GO:0006024)
0.0 3.4 GO:0035264 multicellular organism growth(GO:0035264)
0.0 0.4 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.0 0.5 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.9 GO:0021762 substantia nigra development(GO:0021762)
0.0 1.6 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.0 0.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.3 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.2 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692) cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.0 1.4 GO:0008033 tRNA processing(GO:0008033)
0.0 0.5 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.3 GO:0005513 detection of calcium ion(GO:0005513)
0.0 1.3 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.2 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.0 0.9 GO:0038034 signal transduction in absence of ligand(GO:0038034) extrinsic apoptotic signaling pathway in absence of ligand(GO:0097192)
0.0 0.5 GO:1903959 regulation of anion transmembrane transport(GO:1903959)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 9.0 GO:0043159 acrosomal matrix(GO:0043159)
1.6 4.9 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
1.0 13.0 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.8 2.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.7 3.7 GO:0005797 Golgi medial cisterna(GO:0005797)
0.7 4.4 GO:0097422 tubular endosome(GO:0097422)
0.6 3.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.6 1.8 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.6 1.7 GO:1902737 dendritic filopodium(GO:1902737)
0.5 2.5 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.5 8.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.5 4.5 GO:0097452 GAIT complex(GO:0097452)
0.5 6.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.5 1.4 GO:0000805 X chromosome(GO:0000805)
0.5 9.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.4 3.8 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.4 7.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.3 7.1 GO:0071141 SMAD protein complex(GO:0071141)
0.3 1.2 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.3 5.6 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.3 8.1 GO:0031143 pseudopodium(GO:0031143)
0.3 2.9 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.3 3.8 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.3 9.2 GO:0000421 autophagosome membrane(GO:0000421)
0.2 2.0 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.2 1.0 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.2 0.9 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.2 2.9 GO:0031209 SCAR complex(GO:0031209)
0.2 2.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 3.2 GO:0032059 bleb(GO:0032059)
0.2 2.1 GO:0061574 ASAP complex(GO:0061574)
0.2 1.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 1.4 GO:0044326 dendritic spine neck(GO:0044326)
0.2 1.8 GO:0000125 PCAF complex(GO:0000125)
0.2 1.9 GO:0005688 U6 snRNP(GO:0005688)
0.2 10.7 GO:0031519 PcG protein complex(GO:0031519)
0.2 1.7 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 0.7 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.4 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 0.9 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.6 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 1.4 GO:0070852 cell body fiber(GO:0070852)
0.1 1.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 11.9 GO:0005643 nuclear pore(GO:0005643)
0.1 0.7 GO:0032437 cuticular plate(GO:0032437)
0.1 1.0 GO:0005787 signal peptidase complex(GO:0005787)
0.1 3.6 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 4.3 GO:0090544 BAF-type complex(GO:0090544)
0.1 1.3 GO:0005869 dynactin complex(GO:0005869)
0.1 8.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 2.5 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.4 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 6.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 2.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 5.3 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1 0.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 1.3 GO:0005652 nuclear lamina(GO:0005652)
0.1 0.5 GO:0031010 ISWI-type complex(GO:0031010)
0.1 2.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 6.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 2.2 GO:0032040 small-subunit processome(GO:0032040)
0.1 0.8 GO:0005916 fascia adherens(GO:0005916)
0.1 0.6 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.4 GO:0070449 elongin complex(GO:0070449)
0.0 3.4 GO:0000502 proteasome complex(GO:0000502)
0.0 1.3 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.3 GO:0051286 cell tip(GO:0051286)
0.0 0.5 GO:0032433 filopodium tip(GO:0032433)
0.0 6.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 3.5 GO:0016605 PML body(GO:0016605)
0.0 1.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 4.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 20.1 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.2 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 1.4 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 1.5 GO:0016459 myosin complex(GO:0016459)
0.0 5.4 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.2 GO:0000145 exocyst(GO:0000145)
0.0 1.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 3.2 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.2 GO:1990752 microtubule end(GO:1990752)
0.0 2.6 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.3 GO:0030173 integral component of Golgi membrane(GO:0030173)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.1 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717)
1.4 13.0 GO:1990226 histone methyltransferase binding(GO:1990226)
1.3 13.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
1.2 3.7 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
1.2 10.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.1 9.0 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
1.0 6.1 GO:0035500 MH2 domain binding(GO:0035500)
0.9 7.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.7 5.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.7 7.7 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.7 4.6 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.6 3.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.6 6.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.5 6.8 GO:0017091 AU-rich element binding(GO:0017091)
0.5 1.6 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.5 1.5 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.5 6.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.5 4.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.5 5.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.4 2.6 GO:0034046 poly(G) binding(GO:0034046)
0.4 1.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.4 6.9 GO:0035497 cAMP response element binding(GO:0035497)
0.3 1.0 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.3 1.7 GO:0005294 neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
0.3 1.6 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.3 0.9 GO:0032427 GBD domain binding(GO:0032427)
0.3 1.5 GO:0038025 reelin receptor activity(GO:0038025)
0.3 13.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.3 9.2 GO:0004707 MAP kinase activity(GO:0004707)
0.3 2.6 GO:0043426 MRF binding(GO:0043426)
0.3 1.6 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.3 0.5 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.3 8.3 GO:0070064 proline-rich region binding(GO:0070064)
0.2 2.0 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.2 3.1 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.2 1.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 5.8 GO:0000400 four-way junction DNA binding(GO:0000400)
0.2 3.0 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.2 3.0 GO:0031386 protein tag(GO:0031386)
0.2 2.3 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.2 1.6 GO:0098821 BMP receptor activity(GO:0098821)
0.2 8.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 6.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.2 3.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 3.0 GO:0034452 dynactin binding(GO:0034452)
0.2 1.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2 1.6 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.2 7.8 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.2 0.5 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 1.8 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 1.0 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.1 12.6 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.7 GO:1903135 cupric ion binding(GO:1903135)
0.1 6.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 5.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 4.5 GO:0008143 poly(A) binding(GO:0008143)
0.1 4.3 GO:0001671 ATPase activator activity(GO:0001671)
0.1 1.2 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.1 17.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 4.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 8.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 3.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 1.0 GO:0030957 Tat protein binding(GO:0030957)
0.1 3.8 GO:0042605 peptide antigen binding(GO:0042605)
0.1 6.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 3.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 1.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 1.3 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 3.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.0 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 6.9 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 3.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.8 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.1 0.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 1.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 0.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.6 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.1 1.8 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) triglyceride lipase activity(GO:0004806)
0.1 1.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 2.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.5 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 2.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 1.7 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 1.4 GO:0070628 proteasome binding(GO:0070628)
0.1 0.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.8 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.9 GO:0043422 protein kinase B binding(GO:0043422)
0.0 8.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.0 6.2 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 1.4 GO:0032452 histone demethylase activity(GO:0032452)
0.0 2.3 GO:0008375 acetylglucosaminyltransferase activity(GO:0008375)
0.0 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 8.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 2.5 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.6 GO:0008026 ATP-dependent RNA helicase activity(GO:0004004) ATP-dependent helicase activity(GO:0008026) RNA-dependent ATPase activity(GO:0008186) purine NTP-dependent helicase activity(GO:0070035)
0.0 1.3 GO:0004386 helicase activity(GO:0004386)
0.0 1.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 3.0 GO:0042393 histone binding(GO:0042393)
0.0 0.5 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.9 GO:0019003 GDP binding(GO:0019003)
0.0 0.8 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0070878 primary miRNA binding(GO:0070878)
0.0 3.7 GO:0008201 heparin binding(GO:0008201)
0.0 2.1 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.0 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.7 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.3 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 6.2 GO:0045296 cadherin binding(GO:0045296)
0.0 1.0 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 1.0 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.6 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.0 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.0 0.0 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.3 6.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3 15.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.2 12.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.2 12.5 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.1 7.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 9.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 2.5 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 1.8 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 2.9 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 4.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 7.7 PID E2F PATHWAY E2F transcription factor network
0.1 12.0 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.1 1.8 PID MYC PATHWAY C-MYC pathway
0.1 1.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 4.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 8.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 2.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.5 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.8 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 2.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 2.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 2.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.5 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 3.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.4 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 9.0 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.5 6.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.3 12.7 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.3 10.4 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.3 5.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.3 6.8 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.3 4.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 9.2 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.2 3.8 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 9.1 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.2 7.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 4.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.1 2.5 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 3.1 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 1.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 3.1 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 5.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.5 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.1 4.8 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 6.5 REACTOME TRANSLATION Genes involved in Translation
0.1 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 13.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 10.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 4.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 0.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.0 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 2.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 1.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 2.5 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 2.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 5.6 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 0.8 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.8 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.4 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 2.1 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.3 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+