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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for AUGGCAC

Z-value: 6.13

Motif logo

miRNA associated with seed AUGGCAC

NamemiRBASE accession
MIMAT0000261

Activity profile of AUGGCAC motif

Sorted Z-values of AUGGCAC motif

Network of associatons between targets according to the STRING database.

First level regulatory network of AUGGCAC

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr6_+_110874775 20.25 ENST00000675380.1
ENST00000368882.8
ENST00000368877.9
ENST00000368885.8
ENST00000672937.2
adenosylmethionine decarboxylase 1
chr5_+_65926556 19.18 ENST00000380943.6
ENST00000416865.6
ENST00000380935.5
ENST00000284037.10
erbb2 interacting protein
chr12_-_76559504 18.52 ENST00000547544.5
ENST00000393249.6
oxysterol binding protein like 8
chr5_-_134226059 18.31 ENST00000519718.1
ENST00000481195.6
novel protein
protein phosphatase 2 catalytic subunit alpha
chr3_+_152299392 17.81 ENST00000498502.5
ENST00000545754.5
ENST00000357472.7
ENST00000324196.9
muscleblind like splicing regulator 1
chr15_+_56918612 15.01 ENST00000438423.6
ENST00000267811.9
ENST00000333725.10
ENST00000559609.5
transcription factor 12
chrX_-_20266834 14.10 ENST00000379565.9
ribosomal protein S6 kinase A3
chr8_+_48008409 14.05 ENST00000523432.5
ENST00000521346.5
ENST00000523111.7
ENST00000517630.5
ubiquitin conjugating enzyme E2 V2
chr8_+_26291494 13.60 ENST00000380737.8
ENST00000524169.5
protein phosphatase 2 regulatory subunit Balpha
chr2_-_160493799 13.31 ENST00000348849.8
RNA binding motif single stranded interacting protein 1
chr1_-_93909329 13.26 ENST00000370238.8
ENST00000615724.1
glutamate-cysteine ligase modifier subunit
chr12_+_64404338 12.92 ENST00000332707.10
exportin for tRNA
chr13_+_75549734 12.70 ENST00000563635.5
ENST00000377595.8
novel transcript
ubiquitin C-terminal hydrolase L3
chr15_+_76931704 12.62 ENST00000320963.9
ENST00000394885.8
ENST00000394883.3
reticulocalbin 2
chr13_-_23375431 12.31 ENST00000683270.1
ENST00000684163.1
ENST00000402364.1
ENST00000683367.1
sacsin molecular chaperone
chr3_+_130850585 12.04 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATPase secretory pathway Ca2+ transporting 1
chr2_+_200811882 11.98 ENST00000409600.6
basic leucine zipper and W2 domains 1
chr18_+_32091849 11.85 ENST00000261593.8
ENST00000578914.1
ring finger protein 138
chr6_-_158818225 11.53 ENST00000337147.11
ezrin
chr8_+_97644164 11.39 ENST00000336273.8
metadherin
chr15_-_52569197 10.83 ENST00000563277.5
ENST00000566423.5
cAMP regulated phosphoprotein 19
chr1_-_225653045 10.50 ENST00000366843.6
ENST00000366844.7
ENAH actin regulator
chr12_+_71754834 10.35 ENST00000261263.5
RAB21, member RAS oncogene family
chr1_-_67833448 10.27 ENST00000370982.4
G protein subunit gamma 12
chr8_-_140635617 10.22 ENST00000220592.10
argonaute RISC catalytic component 2
chr7_-_16645728 10.18 ENST00000306999.7
ankyrin repeat and MYND domain containing 2
chr8_+_96261891 9.91 ENST00000517309.6
phosphatidylserine synthase 1
chr19_+_7395112 9.73 ENST00000319670.14
Rho/Rac guanine nucleotide exchange factor 18
chr7_+_39623547 9.30 ENST00000005257.7
RAS like proto-oncogene A
chr5_+_62306228 9.28 ENST00000381103.7
kinesin family member 2A
chr1_-_1891056 9.01 ENST00000378609.9
ENST00000610897.4
ENST00000615252.4
G protein subunit beta 1
chr12_-_92145838 8.74 ENST00000256015.5
BTG anti-proliferation factor 1
chr8_-_102864155 8.53 ENST00000682725.1
ENST00000337198.10
ENST00000681985.1
ENST00000684566.1
ENST00000683787.1
ENST00000682014.1
ENST00000682969.1
ENST00000684721.1
ENST00000347770.8
antizyme inhibitor 1
chr3_+_170222412 8.36 ENST00000295797.5
protein kinase C iota
chr5_+_134525649 7.79 ENST00000282605.8
ENST00000681547.2
ENST00000361895.6
ENST00000402835.5
jade family PHD finger 2
chr8_+_6708626 7.71 ENST00000285518.11
1-acylglycerol-3-phosphate O-acyltransferase 5
chr6_+_160991727 7.67 ENST00000366919.6
ENST00000392142.9
ENST00000366920.6
ENST00000348824.11
mitogen-activated protein kinase kinase kinase 4
chr10_-_32957865 7.62 ENST00000437302.6
ENST00000396033.6
integrin subunit beta 1
chr1_+_70205708 7.55 ENST00000370950.7
serine and arginine rich splicing factor 11
chr2_-_99489955 7.50 ENST00000393445.7
ENST00000258428.8
REV1 DNA directed polymerase
chr3_-_33440343 7.33 ENST00000283629.8
upstream binding protein 1
chr1_-_84506565 7.14 ENST00000370641.3
ENST00000370645.9
G protein subunit gamma 5
chr10_+_22321056 6.94 ENST00000376663.8
BMI1 proto-oncogene, polycomb ring finger
chr8_+_41490553 6.91 ENST00000405786.2
ENST00000357743.9
golgin A7
chr3_+_172040554 6.80 ENST00000336824.8
ENST00000423424.5
fibronectin type III domain containing 3B
chr5_+_69167117 6.69 ENST00000506572.5
ENST00000256442.10
cyclin B1
chr4_+_88007624 6.46 ENST00000237596.7
polycystin 2, transient receptor potential cation channel
chr8_+_109334317 6.28 ENST00000521662.5
ENST00000520147.5
ENST00000521688.6
ENY2 transcription and export complex 2 subunit
chr16_+_85613252 6.19 ENST00000253458.12
ENST00000393243.5
Gse1 coiled-coil protein
chr13_-_25287457 6.18 ENST00000381801.6
myotubularin related protein 6
chr3_-_149971109 6.10 ENST00000239940.11
profilin 2
chr5_+_151771884 5.92 ENST00000627077.2
ENST00000678976.1
ENST00000677408.1
ENST00000678070.1
ENST00000678964.1
ENST00000678925.1
ENST00000394123.7
ENST00000522761.6
ENST00000676827.1
G3BP stress granule assembly factor 1
chr3_-_72446623 5.85 ENST00000477973.4
RING1 and YY1 binding protein
chr14_-_54489003 5.82 ENST00000554908.5
ENST00000616146.4
glia maturation factor beta
chr9_-_125189721 5.81 ENST00000456642.1
ENST00000373547.9
ENST00000415905.5
ENST00000451402.5
protein phosphatase 6 catalytic subunit
chr1_+_203626775 5.58 ENST00000367218.7
ATPase plasma membrane Ca2+ transporting 4
chr15_-_90102448 5.45 ENST00000330062.8
ENST00000559482.5
isocitrate dehydrogenase (NADP(+)) 2
chr17_-_62065248 5.38 ENST00000397786.7
mediator complex subunit 13
chrX_+_41334154 5.20 ENST00000441189.4
ENST00000644513.1
ENST00000644109.1
ENST00000646122.1
ENST00000644074.1
ENST00000644876.2
ENST00000399959.7
ENST00000646319.1
DEAD-box helicase 3 X-linked
chr13_-_31161890 5.19 ENST00000320027.10
heat shock protein family H (Hsp110) member 1
chr5_+_102755269 5.04 ENST00000304400.12
ENST00000455264.7
ENST00000684529.1
ENST00000438793.8
ENST00000682882.1
ENST00000682972.1
ENST00000348126.7
ENST00000512073.1
peptidylglycine alpha-amidating monooxygenase
chr12_+_67269328 5.01 ENST00000545606.6
cullin associated and neddylation dissociated 1
chr15_-_64381431 4.92 ENST00000558008.3
ENST00000300035.9
ENST00000559519.5
ENST00000380258.6
PCNA clamp associated factor
chr9_-_111484353 4.92 ENST00000338205.9
ENST00000684092.1
Ecm29 proteasome adaptor and scaffold
chr13_+_40789548 4.88 ENST00000338625.9
solute carrier family 25 member 15
chr8_+_63168597 4.87 ENST00000539294.6
ENST00000621957.4
ENST00000517371.5
ENST00000621413.4
ENST00000612880.4
YTH N6-methyladenosine RNA binding protein 3
chr14_+_105419813 4.84 ENST00000435036.6
ENST00000331320.12
ENST00000406191.5
metastasis associated 1
chr5_-_143403611 4.75 ENST00000394464.7
ENST00000231509.7
nuclear receptor subfamily 3 group C member 1
chr15_-_65517244 4.64 ENST00000341861.9
dipeptidyl peptidase 8
chr9_+_33025265 4.61 ENST00000330899.5
DnaJ heat shock protein family (Hsp40) member A1
chr2_+_158456939 4.60 ENST00000389759.8
ENST00000628904.2
ENST00000389757.7
plakophilin 4
chr4_-_186723776 4.55 ENST00000614102.4
ENST00000441802.7
FAT atypical cadherin 1
chr2_-_226799806 4.51 ENST00000305123.6
insulin receptor substrate 1
chr5_+_119071358 4.41 ENST00000311085.8
Dmx like 1
chr3_-_100401028 4.38 ENST00000284320.6
translocase of outer mitochondrial membrane 70
chr3_+_37861926 4.27 ENST00000443503.6
CTD small phosphatase like
chr14_+_104865256 4.19 ENST00000414716.8
ENST00000556508.5
ENST00000453495.2
centrosomal protein 170B
chr20_-_543770 4.09 ENST00000460062.7
ENST00000645187.1
ENST00000647348.1
ENST00000217244.9
ENST00000349736.10
casein kinase 2 alpha 1
chrX_-_136880715 4.07 ENST00000431446.7
ENST00000320676.11
ENST00000562646.5
RNA binding motif protein X-linked
chr10_-_112446891 4.05 ENST00000369404.3
ENST00000369405.7
ENST00000626395.2
zinc finger DHHC-type palmitoyltransferase 6
chr2_+_119759875 3.72 ENST00000263708.7
protein tyrosine phosphatase non-receptor type 4
chrX_-_132218124 3.70 ENST00000342983.6
RAP2C, member of RAS oncogene family
chr5_-_138575359 3.65 ENST00000297185.9
ENST00000678300.1
ENST00000677425.1
ENST00000677064.1
ENST00000507115.6
heat shock protein family A (Hsp70) member 9
chr3_-_160565560 3.50 ENST00000334256.9
ENST00000676866.1
ENST00000469804.1
karyopherin subunit alpha 4
chr4_-_39638846 3.49 ENST00000295958.10
small integral membrane protein 14
chr10_+_72273914 3.45 ENST00000681898.1
ENST00000307365.4
DNA damage inducible transcript 4
chr19_-_14206168 3.21 ENST00000361434.7
ENST00000340736.10
adhesion G protein-coupled receptor L1
chr1_-_235328147 3.18 ENST00000264183.9
ENST00000418304.1
ENST00000349213.7
AT-rich interaction domain 4B
chr14_+_101761786 3.15 ENST00000422945.6
ENST00000554442.5
ENST00000556260.6
ENST00000328724.9
ENST00000557268.5
protein phosphatase 2 regulatory subunit B'gamma
chr12_+_19129689 3.10 ENST00000429027.7
ENST00000540972.5
pleckstrin homology domain containing A5
chr1_+_53014926 3.06 ENST00000430330.6
ENST00000408941.7
ENST00000478274.6
ENST00000484100.5
ENST00000435345.6
ENST00000488965.1
sterol carrier protein 2
chr1_+_193121950 2.98 ENST00000367435.5
cell division cycle 73
chr5_-_32174262 2.92 ENST00000265070.7
golgi phosphoprotein 3
chr17_-_1456149 2.80 ENST00000574295.1
ENST00000398970.5
ENST00000300574.3
CRK proto-oncogene, adaptor protein
chr5_-_64768619 2.78 ENST00000513458.9
SREK1 interacting protein 1
chr2_+_105744876 2.75 ENST00000233154.9
ENST00000451463.6
NCK adaptor protein 2
chr2_+_230712817 2.70 ENST00000258418.10
calcium binding protein 39
chr2_-_183038405 2.57 ENST00000361354.9
NCK associated protein 1
chr6_+_7107941 2.56 ENST00000379938.7
ENST00000467782.5
ENST00000334984.10
ENST00000349384.10
ras responsive element binding protein 1
chr1_-_114716729 2.36 ENST00000369535.5
NRAS proto-oncogene, GTPase
chr17_-_76737321 2.36 ENST00000359995.10
ENST00000508921.7
ENST00000583836.1
ENST00000358156.6
ENST00000392485.2
serine and arginine rich splicing factor 2
chr9_+_470291 2.29 ENST00000382303.5
KN motif and ankyrin repeat domains 1
chr15_+_63042632 2.24 ENST00000288398.10
ENST00000358278.7
ENST00000610733.1
ENST00000403994.9
ENST00000357980.9
ENST00000559556.5
ENST00000267996.11
ENST00000559397.6
ENST00000561266.6
ENST00000560970.6
tropomyosin 1
chr1_-_160285120 2.23 ENST00000368072.10
peroxisomal biogenesis factor 19
chr6_+_87472925 2.14 ENST00000369556.7
ENST00000369557.9
ENST00000369552.9
solute carrier family 35 member A1
chr4_+_169620527 2.13 ENST00000360642.7
ENST00000512813.5
ENST00000513761.6
chloride voltage-gated channel 3
chr11_+_112074287 2.07 ENST00000532163.5
ENST00000280352.13
ENST00000393047.8
ENST00000526879.5
ENST00000525785.5
NKAP domain containing 1
chr19_+_34254543 1.98 ENST00000588470.5
ENST00000299505.8
ENST00000589583.5
granule associated Rac and RHOG effector 1
chr2_+_42169332 1.93 ENST00000402711.6
ENST00000318522.10
EMAP like 4
chr14_+_55051639 1.89 ENST00000395468.9
ENST00000622254.1
mitogen-activated protein kinase 1 interacting protein 1 like
chr5_-_78549151 1.87 ENST00000515007.6
LHFPL tetraspan subfamily member 2
chr14_-_50532590 1.70 ENST00000013125.9
mitogen-activated protein kinase kinase kinase kinase 5
chr1_+_174799895 1.70 ENST00000489615.5
RAB GTPase activating protein 1 like
chr8_-_96235533 1.51 ENST00000518406.5
ENST00000287022.10
ENST00000523920.1
ubiquinol-cytochrome c reductase binding protein
chr8_-_23854796 1.50 ENST00000290271.7
stanniocalcin 1
chr5_-_81751103 1.48 ENST00000514493.5
ENST00000320672.8
ENST00000615665.4
single stranded DNA binding protein 2
chr6_-_132513045 1.47 ENST00000367941.7
ENST00000367937.4
syntaxin 7
chr1_-_236604479 1.44 ENST00000366579.1
ENST00000366581.6
ENST00000366582.8
HEAT repeat containing 1
chr6_-_53061740 1.43 ENST00000350082.10
ENST00000356971.3
ENST00000676107.1
ciliogenesis associated kinase 1
chr2_+_168456215 1.36 ENST00000392687.4
ENST00000305747.11
ceramide synthase 6
chr3_+_140941792 1.29 ENST00000446041.6
ENST00000324194.12
ENST00000507429.5
solute carrier family 25 member 36
chr5_-_140346596 1.28 ENST00000230990.7
heparin binding EGF like growth factor
chr7_+_69598465 1.18 ENST00000342771.10
activator of transcription and developmental regulator AUTS2
chr3_+_186783567 1.14 ENST00000323963.10
ENST00000440191.6
eukaryotic translation initiation factor 4A2
chr5_-_168579319 1.08 ENST00000522176.1
ENST00000239231.7
pantothenate kinase 3
chr7_+_155297776 1.05 ENST00000344756.8
ENST00000425172.1
ENST00000340368.9
ENST00000342407.5
insulin induced gene 1
chr6_+_53794948 1.05 ENST00000370888.6
leucine rich repeat containing 1
chr10_-_102502669 0.99 ENST00000487599.1
actin related protein 1A
chr1_+_24745396 0.98 ENST00000374379.9
chloride intracellular channel 4
chr3_-_150546403 0.98 ENST00000239944.7
ENST00000491660.1
ENST00000487153.1
stress associated endoplasmic reticulum protein 1
chr1_-_92792396 0.96 ENST00000370331.5
ENST00000540033.2
ecotropic viral integration site 5
chr10_+_22316375 0.95 ENST00000376836.8
ENST00000456711.5
ENST00000444869.5
ENST00000475460.6
ENST00000602390.5
ENST00000489125.2
COMM domain containing 3
COMMD3-BMI1 readthrough
chr8_+_105318428 0.92 ENST00000407775.7
zinc finger protein, FOG family member 2
chr7_+_138460238 0.92 ENST00000343526.9
tripartite motif containing 24
chr1_-_23980308 0.92 ENST00000374452.9
ENST00000492112.3
ENST00000343255.9
ENST00000344989.10
serine and arginine rich splicing factor 10
chr4_+_147617366 0.91 ENST00000508208.5
ENST00000296582.8
transmembrane protein 184C
chrX_+_12975083 0.86 ENST00000451311.7
ENST00000380636.1
thymosin beta 4 X-linked
chr17_-_39451243 0.65 ENST00000300651.11
ENST00000394287.7
mediator complex subunit 1
chr10_-_33334625 0.64 ENST00000374875.5
ENST00000374822.8
ENST00000374867.7
neuropilin 1
chr2_+_30146941 0.62 ENST00000379520.7
ENST00000379519.7
yippee like 5
chrX_-_15335407 0.61 ENST00000635543.1
ENST00000542278.6
ENST00000482148.6
ENST00000333590.6
ENST00000637296.1
ENST00000634582.1
ENST00000634640.1
phosphatidylinositol glycan anchor biosynthesis class A
chr8_+_26383043 0.57 ENST00000380629.7
BCL2 interacting protein 3 like
chr11_+_61680373 0.51 ENST00000257215.10
diacylglycerol lipase alpha
chr7_-_73522278 0.50 ENST00000404251.1
ENST00000339594.9
bromodomain adjacent to zinc finger domain 1B
chr13_+_21671067 0.49 ENST00000382353.6
fibroblast growth factor 9
chr9_-_78031775 0.44 ENST00000286548.9
G protein subunit alpha q
chr10_-_50623897 0.40 ENST00000361781.7
ENST00000429490.5
ENST00000619438.4
sphingomyelin synthase 1
chr10_-_60944132 0.39 ENST00000337910.10
Rho related BTB domain containing 1
chr6_+_87155537 0.34 ENST00000369577.8
ENST00000518845.1
ENST00000339907.8
ENST00000496806.2
zinc finger protein 292
chr11_-_62805429 0.33 ENST00000294172.7
ENST00000531131.1
ENST00000530875.5
ENST00000531709.6
nuclear RNA export factor 1
chr16_+_57372481 0.26 ENST00000006053.7
C-X3-C motif chemokine ligand 1
chr20_-_41300066 0.25 ENST00000436099.6
ENST00000309060.7
ENST00000373261.5
ENST00000436440.6
ENST00000560364.5
ENST00000560361.5
zinc fingers and homeoboxes 3
chr12_-_6970643 0.25 ENST00000542912.5
ENST00000535923.6
ENST00000545167.5
ENST00000399433.7
ENST00000546111.5
ENST00000440277.6
ENST00000536316.3
prohibitin 2
chr1_+_78004930 0.23 ENST00000370763.6
DnaJ heat shock protein family (Hsp40) member B4
chr17_+_66302606 0.21 ENST00000413366.8
protein kinase C alpha
chr9_-_104928139 0.19 ENST00000423487.6
ENST00000374733.1
ENST00000374736.8
ENST00000678995.1
ATP binding cassette subfamily A member 1
chr2_-_142131004 0.18 ENST00000434794.1
ENST00000389484.8
LDL receptor related protein 1B
chr12_+_68746108 0.15 ENST00000398004.4
solute carrier family 35 member E3
chr10_+_110871903 0.15 ENST00000280154.12
programmed cell death 4
chr1_-_240612147 0.14 ENST00000318160.5
gremlin 2, DAN family BMP antagonist
chr11_-_77820706 0.12 ENST00000440064.2
ENST00000528095.5
ENST00000308488.11
remodeling and spacing factor 1
chr5_-_115625972 0.12 ENST00000333314.3
ENST00000456936.4
TMED7-TICAM2 readthrough
transmembrane p24 trafficking protein 7
chr1_+_215082731 0.09 ENST00000444842.7
potassium two pore domain channel subfamily K member 2
chr12_+_49367440 0.08 ENST00000552918.6
ENST00000553127.5
ENST00000321898.10
spermatogenesis associated serine rich 2
chr14_-_67816574 0.05 ENST00000677026.1
ENST00000555452.1
ENST00000347230.9
ENST00000678386.1
ENST00000676620.1
ENST00000676512.1
zinc finger FYVE-type containing 26

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 13.3 GO:0097069 response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
3.8 19.2 GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
2.9 20.3 GO:0008295 spermine metabolic process(GO:0008215) spermidine biosynthetic process(GO:0008295)
2.8 8.5 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
2.6 18.5 GO:0090204 protein localization to nuclear pore(GO:0090204)
2.3 11.5 GO:1902896 terminal web assembly(GO:1902896)
2.2 6.7 GO:0060623 regulation of chromosome condensation(GO:0060623) cellular response to iron(III) ion(GO:0071283)
2.2 6.5 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587) cellular response to hydrostatic pressure(GO:0071464)
2.0 12.0 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
1.9 7.7 GO:0007538 primary sex determination(GO:0007538)
1.9 5.6 GO:1903248 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
1.8 5.5 GO:0006097 glyoxylate cycle(GO:0006097)
1.7 6.9 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
1.7 10.2 GO:0090625 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
1.7 11.8 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
1.6 4.9 GO:1903352 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
1.6 4.8 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
1.5 31.9 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
1.3 5.0 GO:0001519 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
1.2 9.9 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
1.1 9.8 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
1.1 7.6 GO:0010710 calcium-independent cell-matrix adhesion(GO:0007161) regulation of collagen catabolic process(GO:0010710)
1.0 11.3 GO:0048194 Golgi vesicle budding(GO:0048194)
1.0 3.0 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.9 2.7 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.9 10.3 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.9 2.6 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.8 3.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.8 7.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.8 9.3 GO:0051665 membrane raft localization(GO:0051665)
0.7 5.8 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.7 12.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.7 8.7 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.6 5.2 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.6 8.4 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.6 6.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.6 7.4 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.6 7.8 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.6 6.9 GO:0007379 segment specification(GO:0007379)
0.6 5.0 GO:0010265 SCF complex assembly(GO:0010265)
0.6 7.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.5 14.1 GO:0000729 DNA double-strand break processing(GO:0000729)
0.5 2.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.5 4.8 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.5 3.1 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.5 16.9 GO:0043555 regulation of translation in response to stress(GO:0043555)
0.5 1.4 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.5 9.0 GO:0070208 protein heterotrimerization(GO:0070208)
0.5 4.5 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.4 2.2 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.4 1.3 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.4 3.6 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.4 1.2 GO:2000620 innate vocalization behavior(GO:0098582) positive regulation of histone H4-K16 acetylation(GO:2000620)
0.4 1.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.3 2.8 GO:0001878 response to yeast(GO:0001878)
0.3 0.9 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.3 12.9 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.3 4.4 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.3 1.3 GO:0051541 elastin metabolic process(GO:0051541)
0.3 4.1 GO:0018345 protein palmitoylation(GO:0018345)
0.2 7.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.2 4.9 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.2 1.6 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.2 3.4 GO:0051198 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.2 2.1 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.2 1.5 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.2 4.1 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 2.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.2 9.9 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.2 1.5 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.2 3.7 GO:0032486 Rap protein signal transduction(GO:0032486)
0.2 4.9 GO:0019985 translesion synthesis(GO:0019985)
0.2 6.2 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.2 2.2 GO:0045046 protein import into peroxisome membrane(GO:0045046)
0.2 0.5 GO:0099541 retrograde trans-synaptic signaling(GO:0098917) trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.2 11.6 GO:0031663 lipopolysaccharide-mediated signaling pathway(GO:0031663)
0.2 0.6 GO:0061441 renal artery morphogenesis(GO:0061441)
0.1 2.4 GO:0033197 response to vitamin E(GO:0033197)
0.1 10.1 GO:0008589 regulation of smoothened signaling pathway(GO:0008589)
0.1 15.0 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.1 0.2 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.1 0.9 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) negative regulation of interleukin-8 secretion(GO:2000483)
0.1 2.6 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.1 5.0 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.1 15.7 GO:0045445 myoblast differentiation(GO:0045445)
0.1 3.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 4.1 GO:0071174 mitotic spindle checkpoint(GO:0071174)
0.1 3.2 GO:0035584 calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.1 9.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 4.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.1 0.2 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.1 1.0 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 1.7 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.1 0.3 GO:0051040 regulation of calcium-independent cell-cell adhesion(GO:0051040)
0.1 8.8 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.1 2.4 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.1 5.8 GO:0048207 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 0.6 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.1 GO:0060300 regulation of cytokine activity(GO:0060300)
0.1 1.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 4.4 GO:0071806 protein transmembrane transport(GO:0071806)
0.1 9.7 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 0.4 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 7.3 GO:0019079 viral genome replication(GO:0019079)
0.0 1.1 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 1.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 9.7 GO:0006260 DNA replication(GO:0006260)
0.0 2.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.9 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 4.1 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.6 GO:0032508 DNA duplex unwinding(GO:0032508)
0.0 1.8 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 0.1 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 2.7 GO:0007163 establishment or maintenance of cell polarity(GO:0007163)
0.0 1.9 GO:0002576 platelet degranulation(GO:0002576)
0.0 1.0 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 13.3 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
3.8 11.5 GO:0044393 microspike(GO:0044393)
2.5 7.6 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
1.7 6.7 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
1.3 10.3 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
1.3 6.5 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
1.3 14.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
1.2 12.3 GO:0070852 cell body fiber(GO:0070852)
1.2 6.9 GO:0002178 palmitoyltransferase complex(GO:0002178)
1.1 11.4 GO:0046581 intercellular canaliculus(GO:0046581)
1.1 4.5 GO:0005899 insulin receptor complex(GO:0005899)
1.0 10.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.9 4.6 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.9 4.4 GO:0043291 RAVE complex(GO:0043291)
0.9 34.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.8 19.2 GO:0030056 hemidesmosome(GO:0030056)
0.6 4.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.6 4.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.5 4.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.5 9.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.5 1.4 GO:0034455 t-UTP complex(GO:0034455)
0.5 2.4 GO:0035061 interchromatin granule(GO:0035061)
0.5 14.9 GO:0097228 sperm principal piece(GO:0097228)
0.4 6.3 GO:0000124 SAGA complex(GO:0000124)
0.4 6.6 GO:0035102 PRC1 complex(GO:0035102)
0.4 8.4 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.4 2.6 GO:0031209 SCAR complex(GO:0031209)
0.4 28.9 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.4 11.8 GO:0035861 site of double-strand break(GO:0035861)
0.3 0.9 GO:0005726 perichromatin fibrils(GO:0005726)
0.3 3.0 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.3 17.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 1.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 5.2 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.2 1.0 GO:0002177 manchette(GO:0002177)
0.2 2.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 6.0 GO:0016592 mediator complex(GO:0016592)
0.1 16.8 GO:0005643 nuclear pore(GO:0005643)
0.1 9.3 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 4.6 GO:0051233 spindle midzone(GO:0051233)
0.1 1.5 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.1 14.7 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 10.0 GO:0030175 filopodium(GO:0030175)
0.1 7.8 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.1 0.5 GO:0043196 varicosity(GO:0043196)
0.1 0.6 GO:0097443 sorting endosome(GO:0097443)
0.1 3.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 0.6 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1 10.7 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 3.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 13.1 GO:0005802 trans-Golgi network(GO:0005802)
0.1 1.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 3.2 GO:0042734 presynaptic membrane(GO:0042734)
0.0 5.7 GO:0005819 spindle(GO:0005819)
0.0 1.3 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 6.1 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 5.7 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 8.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.5 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 9.1 GO:0005874 microtubule(GO:0005874)
0.0 1.5 GO:0055037 recycling endosome(GO:0055037)
0.0 1.0 GO:0005902 microvillus(GO:0005902)
0.0 6.5 GO:0031965 nuclear membrane(GO:0031965)
0.0 9.2 GO:0016607 nuclear speck(GO:0016607)
0.0 9.3 GO:0005929 cilium(GO:0005929)
0.0 6.6 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.9 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.0 6.2 GO:0019866 mitochondrial inner membrane(GO:0005743) organelle inner membrane(GO:0019866)
0.0 2.1 GO:0042581 specific granule(GO:0042581)
0.0 0.8 GO:0043195 terminal bouton(GO:0043195)
0.0 0.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 17.8 GO:0001069 regulatory region RNA binding(GO:0001069)
4.4 13.3 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
3.4 10.2 GO:0098808 mRNA cap binding(GO:0098808)
3.1 9.3 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
2.3 9.0 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
1.9 5.6 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
1.8 5.5 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
1.6 4.9 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
1.4 12.7 GO:0019784 NEDD8-specific protease activity(GO:0019784)
1.3 5.2 GO:0043273 CTPase activity(GO:0043273)
1.3 6.5 GO:0048763 calcium-induced calcium release activity(GO:0048763)
1.3 5.0 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
1.2 8.5 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
1.1 24.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
1.1 6.7 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
1.1 19.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
1.0 3.1 GO:0070538 oleic acid binding(GO:0070538)
1.0 7.6 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
1.0 4.8 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.9 6.6 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.9 10.3 GO:0042301 phosphate ion binding(GO:0042301)
0.9 18.3 GO:0050811 GABA receptor binding(GO:0050811)
0.8 3.2 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.8 15.0 GO:0035497 cAMP response element binding(GO:0035497)
0.7 5.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.6 11.0 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.5 2.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.5 13.6 GO:0048156 tau protein binding(GO:0048156)
0.5 11.5 GO:0044548 S100 protein binding(GO:0044548)
0.5 12.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.5 12.3 GO:0070628 proteasome binding(GO:0070628)
0.4 1.3 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.4 4.6 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.4 4.9 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.4 5.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.4 20.3 GO:0016831 carboxy-lyase activity(GO:0016831)
0.3 11.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.3 6.0 GO:0042809 vitamin D receptor binding(GO:0042809)
0.3 8.6 GO:0004697 protein kinase C activity(GO:0004697)
0.3 14.1 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.3 12.9 GO:0000049 tRNA binding(GO:0000049)
0.3 11.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.3 14.1 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.3 7.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.3 3.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.3 6.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.3 2.2 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.3 2.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.2 4.4 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.2 10.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.2 10.5 GO:0050699 WW domain binding(GO:0050699)
0.2 7.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 1.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 4.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 1.5 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 0.9 GO:0034056 estrogen response element binding(GO:0034056)
0.2 1.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 14.1 GO:0019003 GDP binding(GO:0019003)
0.2 7.3 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 0.4 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 5.0 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 1.5 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.9 GO:0050733 RS domain binding(GO:0050733)
0.1 0.4 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 6.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.6 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.1 3.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 8.3 GO:0003777 microtubule motor activity(GO:0003777)
0.1 7.1 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.1 7.5 GO:0003684 damaged DNA binding(GO:0003684)
0.1 3.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 14.4 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 1.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 9.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 4.4 GO:0004407 histone deacetylase activity(GO:0004407)
0.1 3.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 0.6 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.2 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.1 2.8 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.1 2.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 2.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 3.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.5 GO:0035173 histone kinase activity(GO:0035173)
0.0 2.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 3.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 3.6 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 3.2 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.6 GO:0005521 lamin binding(GO:0005521)
0.0 2.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 1.0 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 7.6 GO:0003712 transcription cofactor activity(GO:0003712)
0.0 0.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 1.5 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.1 GO:0022841 potassium ion leak channel activity(GO:0022841)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 9.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.5 34.3 PID PLK1 PATHWAY PLK1 signaling events
0.4 14.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.3 19.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.3 11.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.3 20.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.3 7.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.2 4.5 PID S1P S1P2 PATHWAY S1P2 pathway
0.2 2.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 8.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.2 13.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.2 21.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 6.1 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 9.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 1.8 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 4.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 1.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 5.9 PID E2F PATHWAY E2F transcription factor network
0.0 1.7 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.0 PID AURORA B PATHWAY Aurora B signaling
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 26.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
1.1 18.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
1.0 20.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.6 8.4 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.6 13.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.5 9.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.5 25.6 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.5 6.7 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.5 11.7 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.4 7.6 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.4 7.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.4 19.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.4 9.3 REACTOME KINESINS Genes involved in Kinesins
0.3 0.3 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.2 7.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.2 11.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 12.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 13.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 9.9 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.2 5.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.2 3.1 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.2 3.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 4.7 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 6.2 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 8.5 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 23.7 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 2.7 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 7.5 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.1 2.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 5.0 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 3.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.1 1.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.1 1.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 2.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 7.1 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 4.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 4.1 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 2.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 4.9 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.5 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.1 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.0 REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES Genes involved in Recruitment of mitotic centrosome proteins and complexes
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport