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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for BACH2

Z-value: 7.56

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Transcription factors associated with BACH2

Gene Symbol Gene ID Gene Info
ENSG00000112182.15 BACH2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BACH2hg38_v1_chr6_-_90296908_90296922,
hg38_v1_chr6_-_90296824_90296851
-0.407.6e-10Click!

Activity profile of BACH2 motif

Sorted Z-values of BACH2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of BACH2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr16_+_89921851 28.57 ENST00000554444.5
ENST00000556565.5
tubulin beta 3 class III
chr7_-_96709780 26.02 ENST00000623693.3
ENST00000623498.3
ENST00000488005.5
ENST00000413065.5
SEM1 26S proteasome complex subunit
chr11_-_64245816 25.81 ENST00000542235.1
protein phosphatase 1 regulatory inhibitor subunit 14B
chr1_+_223701582 23.89 ENST00000433674.6
calpain 2
chr17_-_75154534 23.32 ENST00000356033.8
Jupiter microtubule associated homolog 1
chr11_-_64246190 23.09 ENST00000392210.6
protein phosphatase 1 regulatory inhibitor subunit 14B
chr9_-_124415421 22.11 ENST00000259457.8
ENST00000441097.1
proteasome 20S subunit beta 7
chr1_+_26280117 19.62 ENST00000319041.6
SH3 domain binding glutamate rich protein like 3
chr12_-_119804472 19.41 ENST00000678087.1
ENST00000677993.1
citron rho-interacting serine/threonine kinase
chr14_+_103334803 19.24 ENST00000561325.5
ENST00000392715.6
ENST00000559130.5
ENST00000559532.5
ENST00000558506.1
eukaryotic translation initiation factor 5
chr9_-_127874964 19.15 ENST00000373156.5
adenylate kinase 1
chr6_-_31736504 18.94 ENST00000616760.1
ENST00000375784.7
ENST00000375779.6
chloride intracellular channel 1
chr17_+_37491464 18.81 ENST00000613659.1
dual specificity phosphatase 14
chr12_-_119804298 18.76 ENST00000678652.1
ENST00000678494.1
citron rho-interacting serine/threonine kinase
chr11_-_2929412 17.76 ENST00000314222.5
pleckstrin homology like domain family A member 2
chr5_+_138753412 17.74 ENST00000520339.5
ENST00000627109.2
ENST00000302763.12
ENST00000518910.5
catenin alpha 1
chr16_+_57628684 17.67 ENST00000567397.5
ENST00000568979.5
ENST00000672974.1
adhesion G protein-coupled receptor G1
chr2_+_231056845 17.57 ENST00000677230.1
ENST00000677259.1
ENST00000677180.1
ENST00000409643.6
ENST00000619128.5
ENST00000678679.1
ENST00000676740.1
ENST00000308696.11
ENST00000440838.5
ENST00000373635.9
proteasome 26S subunit, non-ATPase 1
chr17_-_67366562 17.32 ENST00000356126.8
ENST00000357146.4
proteasome 26S subunit, non-ATPase 12
chr15_-_22980334 16.76 ENST00000610365.4
ENST00000617928.5
ENST00000611832.4
cytoplasmic FMR1 interacting protein 1
chr9_+_137241277 16.48 ENST00000340384.5
tubulin beta 4B class IVb
chr3_+_184299198 16.39 ENST00000417952.5
ENST00000310118.9
proteasome 26S subunit, non-ATPase 2
chr6_+_44227025 15.60 ENST00000371708.1
solute carrier family 29 member 1 (Augustine blood group)
chr1_+_156126160 15.59 ENST00000448611.6
ENST00000368297.5
lamin A/C
chr1_-_109426410 15.49 ENST00000271308.9
proteasome 20S subunit alpha 5
chr16_+_30065753 15.44 ENST00000642816.3
ENST00000643777.4
ENST00000569798.5
aldolase, fructose-bisphosphate A
chr16_+_74296789 14.57 ENST00000219313.9
ENST00000567958.5
ENST00000568615.2
proteasome 26S subunit, non-ATPase 7
chr3_+_184176949 14.53 ENST00000432591.5
ENST00000431779.5
ENST00000621863.4
adaptor related protein complex 2 subunit mu 1
chr5_+_160009113 14.38 ENST00000522793.5
ENST00000682719.1
ENST00000684137.1
ENST00000683219.1
ENST00000684018.1
ENST00000231238.10
ENST00000682131.1
tetratricopeptide repeat domain 1
chr1_+_36155930 14.31 ENST00000316156.8
MAP7 domain containing 1
chr6_+_30717433 14.08 ENST00000681435.1
tubulin beta class I
chrX_-_15493234 13.86 ENST00000380420.10
pirin
chr19_+_36139953 13.80 ENST00000589146.5
ENST00000628018.2
ENST00000628306.2
calpain small subunit 1
chr21_+_31659666 13.61 ENST00000389995.4
ENST00000270142.11
superoxide dismutase 1
chr19_+_36140059 13.61 ENST00000246533.8
ENST00000587718.5
ENST00000592483.5
ENST00000590874.5
ENST00000588815.5
calpain small subunit 1
chr6_+_149749695 13.37 ENST00000367380.9
ENST00000544496.5
ENST00000649295.1
ENST00000464889.7
protein-L-isoaspartate (D-aspartate) O-methyltransferase
chr1_+_156126525 13.27 ENST00000504687.6
ENST00000473598.6
lamin A/C
chr1_+_36156096 13.11 ENST00000474796.2
ENST00000373150.8
ENST00000373151.6
MAP7 domain containing 1
chr12_-_52949818 13.04 ENST00000546897.5
ENST00000552551.5
keratin 8
chr4_-_73223082 12.80 ENST00000509867.6
ankyrin repeat domain 17
chr15_+_75043263 12.78 ENST00000563393.1
phosphopantothenoylcysteine decarboxylase
chr11_-_65900375 12.13 ENST00000312562.7
FOS like 1, AP-1 transcription factor subunit
chr6_+_2988606 12.07 ENST00000380472.7
ENST00000605901.1
ENST00000454015.1
N-ribosyldihydronicotinamide:quinone reductase 2
long intergenic non-protein coding RNA 1011
chr7_-_96709855 11.99 ENST00000444799.5
ENST00000417009.5
ENST00000248566.3
SEM1 26S proteasome complex subunit
chr3_-_98522514 11.58 ENST00000503004.5
ENST00000506575.1
ENST00000513452.5
ENST00000515620.5
claudin domain containing 1
chr11_-_65900413 11.51 ENST00000448083.6
ENST00000531493.5
ENST00000532401.1
FOS like 1, AP-1 transcription factor subunit
chr11_-_67356970 11.31 ENST00000532830.5
DNA polymerase delta 4, accessory subunit
chr20_+_45406560 11.23 ENST00000372717.5
ENST00000360981.8
dysbindin domain containing 2
chr1_+_156114251 11.16 ENST00000361308.9
lamin A/C
chr1_-_153985366 10.96 ENST00000614713.4
RAB13, member RAS oncogene family
chr7_+_99408609 10.84 ENST00000403633.6
BUD31 homolog
chr11_+_102112445 10.83 ENST00000524575.5
Yes1 associated transcriptional regulator
chr6_+_63571702 10.83 ENST00000672924.1
protein tyrosine phosphatase 4A1
chr15_-_60397964 10.79 ENST00000558998.5
ENST00000560165.5
ENST00000557986.5
ENST00000559467.5
ENST00000677968.1
ENST00000678450.1
ENST00000332680.8
ENST00000396024.7
ENST00000557906.6
ENST00000558558.6
ENST00000559113.6
ENST00000559780.6
ENST00000559956.6
ENST00000560468.6
ENST00000678870.1
ENST00000678061.1
ENST00000451270.7
ENST00000421017.6
ENST00000560466.5
ENST00000558132.5
ENST00000559370.5
ENST00000559725.5
ENST00000558985.6
ENST00000679109.1
annexin A2
chr17_+_81683963 10.69 ENST00000676462.1
ENST00000679336.1
ENST00000678196.1
ENST00000677243.1
ENST00000677044.1
ENST00000677109.1
ENST00000677484.1
ENST00000678105.1
ENST00000677209.1
ENST00000329138.9
ENST00000677225.1
ENST00000678866.1
ENST00000676729.1
ENST00000572392.2
ENST00000577012.1
hepatocyte growth factor-regulated tyrosine kinase substrate
chr1_+_156114700 10.49 ENST00000677389.1
ENST00000368300.9
ENST00000368299.7
lamin A/C
chr1_-_27490130 10.26 ENST00000618852.5
WASP family member 2
chr5_+_102808057 10.18 ENST00000684043.1
ENST00000682407.1
peptidylglycine alpha-amidating monooxygenase
chr12_+_64404338 10.05 ENST00000332707.10
exportin for tRNA
chr6_+_44247087 9.86 ENST00000353801.7
ENST00000371646.10
heat shock protein 90 alpha family class B member 1
chr20_+_45406162 9.76 ENST00000357275.6
ENST00000372720.7
dysbindin domain containing 2
chr5_-_176416222 9.59 ENST00000508425.5
clathrin light chain B
chr15_+_44537085 9.56 ENST00000424492.7
eukaryotic translation initiation factor 3 subunit J
chr1_-_211675557 9.33 ENST00000366998.4
ENST00000366999.9
ENST00000540251.5
NIMA related kinase 2
chr7_-_23347704 8.98 ENST00000619562.4
insulin like growth factor 2 mRNA binding protein 3
chr17_+_32444379 8.94 ENST00000578213.5
ENST00000649012.1
ENST00000457654.6
ENST00000579451.1
ENST00000261712.8
proteasome 26S subunit, non-ATPase 11
chr17_-_78925376 8.76 ENST00000262768.11
TIMP metallopeptidase inhibitor 2
chr10_+_84139491 8.56 ENST00000372134.6
growth hormone inducible transmembrane protein
chr17_+_32350132 8.49 ENST00000321233.10
ENST00000394673.6
ENST00000394670.9
ENST00000579634.5
ENST00000580759.5
ENST00000342555.10
ENST00000577908.5
ENST00000394679.9
ENST00000582165.1
zinc finger protein 207
chr16_+_30065777 8.42 ENST00000395240.7
ENST00000566846.5
aldolase, fructose-bisphosphate A
chr10_+_119651372 8.14 ENST00000369085.8
BAG cochaperone 3
chr10_+_87095169 8.06 ENST00000298784.5
ENST00000298786.5
shieldin complex subunit 2
chr7_+_150368189 8.06 ENST00000519397.1
ENST00000479668.5
replication initiator 1
chr7_+_48088596 8.00 ENST00000416681.5
ENST00000331803.8
ENST00000432131.5
uridine phosphorylase 1
chr5_-_176416523 7.94 ENST00000502877.1
ENST00000310418.9
ENST00000345807.7
clathrin light chain B
chr6_-_138107412 7.76 ENST00000421351.4
p53 apoptosis effector related to PMP22
chr3_-_98522869 7.72 ENST00000502288.5
ENST00000512147.5
ENST00000341181.11
ENST00000510541.5
ENST00000503621.5
ENST00000511081.5
ENST00000507874.5
ENST00000502299.5
ENST00000508659.5
ENST00000510545.5
ENST00000511667.5
ENST00000394185.6
claudin domain containing 1
chr6_-_83431038 7.69 ENST00000369705.4
malic enzyme 1
chr9_-_32573150 7.66 ENST00000379847.8
ENST00000350021.2
NADH:ubiquinone oxidoreductase subunit B6
chr3_+_69084929 7.54 ENST00000273258.4
ADP ribosylation factor like GTPase 6 interacting protein 5
chr1_-_151992571 7.11 ENST00000368809.1
S100 calcium binding protein A10
chr17_-_18258556 6.85 ENST00000579294.5
ENST00000628188.1
ENST00000545457.6
ENST00000578558.5
ENST00000327031.9
FLII actin remodeling protein
chr7_+_148698857 6.84 ENST00000663835.1
ENST00000655324.1
ENST00000662132.1
ENST00000666124.1
ENST00000325222.9
ENST00000660240.1
cullin 1
chr6_-_35921079 6.82 ENST00000507909.1
ENST00000373825.7
SRSF protein kinase 1
chr3_-_49358320 6.76 ENST00000643797.1
ENST00000646881.2
ENST00000496791.2
glutathione peroxidase 1
chr1_+_150508074 6.70 ENST00000369049.8
extracellular matrix protein 1
chr6_-_35921128 6.58 ENST00000510290.5
ENST00000423325.6
SRSF protein kinase 1
chr6_-_158818225 6.43 ENST00000337147.11
ezrin
chr9_-_111484353 6.42 ENST00000338205.9
ENST00000684092.1
Ecm29 proteasome adaptor and scaffold
chr22_-_30246739 6.27 ENST00000403987.3
ENST00000249075.4
LIF interleukin 6 family cytokine
chr9_-_32573173 6.24 ENST00000366466.5
NADH:ubiquinone oxidoreductase subunit B6
chr20_+_37179310 6.22 ENST00000373632.8
ENST00000237530.11
ribophorin II
chr4_+_169660062 6.20 ENST00000507875.5
ENST00000613795.4
chloride voltage-gated channel 3
chrX_+_41334154 6.18 ENST00000441189.4
ENST00000644513.1
ENST00000644109.1
ENST00000646122.1
ENST00000644074.1
ENST00000644876.2
ENST00000399959.7
ENST00000646319.1
DEAD-box helicase 3 X-linked
chr16_+_22297375 6.17 ENST00000615879.4
ENST00000299853.10
ENST00000564209.5
ENST00000565358.5
ENST00000418581.6
ENST00000564883.5
ENST00000359210.8
ENST00000563024.5
RNA polymerase III subunit E
chr3_-_49358272 6.10 ENST00000419349.2
glutathione peroxidase 1
chr17_+_32142560 6.08 ENST00000354266.7
ENST00000581094.5
ENST00000394692.6
ras homolog family member T1
chr14_-_75176593 5.97 ENST00000303575.9
transmembrane p24 trafficking protein 10
chr3_+_69084973 5.90 ENST00000478935.1
ADP ribosylation factor like GTPase 6 interacting protein 5
chr17_+_32142454 5.77 ENST00000333942.10
ENST00000358365.7
ENST00000545287.7
ras homolog family member T1
chr17_-_7687427 5.77 ENST00000514944.5
ENST00000503591.1
ENST00000610292.4
ENST00000420246.6
ENST00000455263.6
ENST00000610538.4
ENST00000622645.4
ENST00000445888.6
ENST00000619485.4
ENST00000509690.5
ENST00000604348.5
ENST00000269305.9
ENST00000620739.4
tumor protein p53
chr1_+_155135344 5.71 ENST00000484157.5
solute carrier family 50 member 1
chr20_+_37179109 5.56 ENST00000373622.9
ribophorin II
chr15_+_44537136 5.39 ENST00000261868.10
ENST00000535391.5
eukaryotic translation initiation factor 3 subunit J
chr18_+_58196736 5.31 ENST00000675221.1
NEDD4 like E3 ubiquitin protein ligase
chr5_-_138575359 5.18 ENST00000297185.9
ENST00000678300.1
ENST00000677425.1
ENST00000677064.1
ENST00000507115.6
heat shock protein family A (Hsp70) member 9
chrX_-_130110479 5.15 ENST00000308167.10
E74 like ETS transcription factor 4
chr2_+_171687501 5.05 ENST00000508530.5
dynein cytoplasmic 1 intermediate chain 2
chrX_+_41333905 4.94 ENST00000457138.7
ENST00000643821.1
DEAD-box helicase 3 X-linked
chr1_+_150508099 4.86 ENST00000346569.6
ENST00000369047.9
extracellular matrix protein 1
chr17_+_77319465 4.86 ENST00000329047.13
septin 9
chr7_-_103344588 4.85 ENST00000426036.6
ENST00000249270.11
ENST00000379263.8
ENST00000454277.5
ENST00000412522.1
DnaJ heat shock protein family (Hsp40) member C2
chr3_+_141368497 4.83 ENST00000321464.7
zinc finger and BTB domain containing 38
chr14_-_22957128 4.77 ENST00000342454.12
ENST00000555986.5
ENST00000554516.5
ENST00000347758.6
ENST00000206474.11
ENST00000555040.5
HAUS augmin like complex subunit 4
chr6_+_44247866 4.75 ENST00000371554.2
heat shock protein 90 alpha family class B member 1
chr12_-_55728994 4.70 ENST00000257857.9
CD63 molecule
chrX_-_130110679 4.54 ENST00000335997.11
E74 like ETS transcription factor 4
chr3_-_11568764 4.46 ENST00000424529.6
vestigial like family member 4
chr11_-_66336396 4.41 ENST00000627248.1
ENST00000311320.9
Ras and Rab interactor 1
chr17_+_21288029 4.21 ENST00000526076.6
ENST00000361818.9
ENST00000316920.10
mitogen-activated protein kinase kinase 3
chr12_-_55728977 4.09 ENST00000552164.5
CD63 molecule
chr7_+_116672187 4.05 ENST00000318493.11
ENST00000397752.8
MET proto-oncogene, receptor tyrosine kinase
chr11_-_62556230 4.03 ENST00000530285.5
AHNAK nucleoprotein
chr14_-_22957061 3.97 ENST00000557591.5
ENST00000541587.6
ENST00000490506.5
ENST00000554406.1
HAUS augmin like complex subunit 4
chr1_-_6602885 3.77 ENST00000377663.3
kelch like family member 21
chr5_+_179820895 3.75 ENST00000504627.1
ENST00000389805.9
ENST00000510187.5
sequestosome 1
chr5_-_177496802 3.74 ENST00000506161.5
PDZ and LIM domain 7
chr14_-_22957100 3.70 ENST00000555367.5
HAUS augmin like complex subunit 4
chr6_-_43629222 3.70 ENST00000307126.10
GTP binding protein 2
chr1_-_51878711 3.70 ENST00000352171.12
nardilysin convertase
chr6_+_12957347 3.65 ENST00000482982.2
phosphatase and actin regulator 1
chr7_+_143381286 3.63 ENST00000449630.5
ENST00000322764.10
ENST00000457235.5
zyxin
chr1_-_156705575 3.55 ENST00000368222.8
cellular retinoic acid binding protein 2
chr19_+_19405655 3.52 ENST00000683918.1
GATA zinc finger domain containing 2A
chr17_+_57085092 3.39 ENST00000575322.1
ENST00000337714.8
A-kinase anchoring protein 1
chr3_-_49786194 3.29 ENST00000613416.4
inositol hexakisphosphate kinase 1
chr16_+_57628507 3.22 ENST00000456916.5
ENST00000567154.5
ENST00000388813.9
ENST00000562558.6
ENST00000566271.6
ENST00000563374.5
ENST00000673126.2
ENST00000562631.7
ENST00000568234.5
ENST00000565770.5
ENST00000566164.5
adhesion G protein-coupled receptor G1
chr1_-_6602859 3.05 ENST00000377658.8
kelch like family member 21
chr8_-_58659742 2.94 ENST00000038176.8
neutral sphingomyelinase activation associated factor
chr11_-_102798148 2.89 ENST00000315274.7
matrix metallopeptidase 1
chr2_-_11344580 2.88 ENST00000616279.4
ENST00000315872.11
Rho associated coiled-coil containing protein kinase 2
chr5_-_177496845 2.87 ENST00000506537.1
PDZ and LIM domain 7
chr15_+_88639009 2.84 ENST00000306072.10
interferon stimulated exonuclease gene 20
chr5_-_88785493 2.81 ENST00000503554.4
myocyte enhancer factor 2C
chr18_+_63775369 2.79 ENST00000540675.5
serpin family B member 7
chr19_-_10339610 2.77 ENST00000589261.5
ENST00000160262.10
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
intercellular adhesion molecule 3
chr8_-_30658176 2.76 ENST00000355904.9
general transcription factor IIE subunit 2
chr1_-_153549120 2.66 ENST00000368712.1
S100 calcium binding protein A3
chr4_+_73740541 2.64 ENST00000401931.1
ENST00000307407.8
C-X-C motif chemokine ligand 8
chr17_+_7219857 2.62 ENST00000583312.5
ENST00000350303.9
ENST00000584103.5
ENST00000356839.10
ENST00000579886.2
acyl-CoA dehydrogenase very long chain
chr1_-_11858935 2.57 ENST00000376468.4
natriuretic peptide B
chr17_+_82217929 2.54 ENST00000580098.6
solute carrier family 16 member 3
chr17_-_50707855 2.39 ENST00000285243.7
ankyrin repeat domain 40
chr18_+_63775395 2.38 ENST00000398019.7
serpin family B member 7
chr13_-_35855627 2.36 ENST00000379893.5
doublecortin like kinase 1
chr18_-_49557 2.33 ENST00000308911.8
tubulin beta 8B
chr7_-_99408548 2.24 ENST00000626285.1
ENST00000350498.8
PDGFA associated protein 1
chr11_-_2903490 2.21 ENST00000455942.3
ENST00000625099.4
solute carrier family 22 member 18 antisense
chr3_-_49786508 2.17 ENST00000395238.5
ENST00000468463.5
ENST00000321599.9
ENST00000460540.1
inositol hexakisphosphate kinase 1
chr11_+_35618450 2.15 ENST00000317811.6
four-jointed box kinase 1
chr19_-_55370455 2.11 ENST00000264563.7
ENST00000585513.1
ENST00000590625.5
interleukin 11
chr11_+_20599602 2.11 ENST00000525748.6
solute carrier family 6 member 5
chr12_-_7665897 2.08 ENST00000229304.5
apolipoprotein B mRNA editing enzyme catalytic subunit 1
chr1_-_153549238 1.99 ENST00000368713.8
S100 calcium binding protein A3
chr17_-_29176752 1.76 ENST00000533112.5
myosin XVIIIA
chr4_-_145098541 1.69 ENST00000613466.4
ENST00000514390.5
anaphase promoting complex subunit 10
chr4_+_677922 1.65 ENST00000400159.6
myosin light chain 5
chr18_+_34710307 1.51 ENST00000679796.1
dystrobrevin alpha
chr17_-_41382298 1.51 ENST00000394001.3
keratin 34
chr18_+_63476927 1.44 ENST00000489441.5
ENST00000382771.9
ENST00000424602.1
serpin family B member 5
chr16_+_67537439 1.40 ENST00000428437.6
ENST00000569253.5
RHO family interacting cell polarization regulator 1
chr22_+_20507571 1.40 ENST00000414658.5
ENST00000432052.5
ENST00000292733.11
ENST00000263205.11
ENST00000406969.5
mediator complex subunit 15
chr6_+_12957301 1.40 ENST00000676234.1
phosphatase and actin regulator 1
chr17_+_75721327 1.38 ENST00000579662.5
integrin subunit beta 4
chr3_+_188212931 1.38 ENST00000618621.4
ENST00000640853.1
LIM domain containing preferred translocation partner in lipoma
chr1_-_39691393 1.32 ENST00000372844.8
hippocalcin like 4
chr11_+_10455292 1.32 ENST00000396553.6
adenosine monophosphate deaminase 3
chr3_+_121593363 1.26 ENST00000338040.6
F-box protein 40
chr18_+_34710249 1.13 ENST00000680346.1
ENST00000348997.9
ENST00000681274.1
ENST00000680822.1
ENST00000680767.2
ENST00000597599.5
ENST00000444659.6
dystrobrevin alpha
chr1_-_51878799 1.10 ENST00000354831.11
ENST00000544028.5
nardilysin convertase
chr5_-_88731827 1.08 ENST00000627170.2
myocyte enhancer factor 2C
chr1_-_39691450 1.01 ENST00000612703.3
ENST00000617690.2
hippocalcin like 4
chr16_+_15502266 1.00 ENST00000452191.6
bMERB domain containing 1
chr1_+_154405193 0.89 ENST00000622330.4
ENST00000344086.8
interleukin 6 receptor
chr15_+_86079863 0.88 ENST00000614907.3
ENST00000441037.7
ATP/GTP binding protein like 1
chr1_+_203127678 0.82 ENST00000640524.1
ENST00000337894.9
adenosine A1 receptor
chr22_+_22030934 0.80 ENST00000390282.2
immunoglobulin lambda variable 4-69
chr6_-_30717264 0.80 ENST00000376406.8
mediator of DNA damage checkpoint 1
chr18_+_23873000 0.77 ENST00000269217.11
ENST00000587184.5
laminin subunit alpha 3
chr2_+_219279330 0.69 ENST00000425450.5
ENST00000392086.8
ENST00000421532.5
ENST00000336576.10
DnaJ heat shock protein family (Hsp40) member B2
chr16_+_58500135 0.69 ENST00000563978.5
ENST00000569923.5
ENST00000356752.8
ENST00000563799.5
ENST00000562999.5
ENST00000570248.5
ENST00000562731.5
ENST00000568424.1
NDRG family member 4
chr4_-_674246 0.69 ENST00000304312.5
ATP synthase membrane subunit e
chr15_+_88638947 0.67 ENST00000559876.2
interferon stimulated exonuclease gene 20
chrX_-_15270031 0.61 ENST00000380483.7
ENST00000380485.7
ENST00000380488.9
ankyrin repeat and SOCS box containing 9
chr4_-_993376 0.56 ENST00000398520.6
ENST00000398516.3
solute carrier family 26 member 1
chr3_+_48466222 0.55 ENST00000625293.3
ENST00000492235.2
ENST00000635452.2
ENST00000456089.1
three prime repair exonuclease 1
chr1_-_179143044 0.55 ENST00000504405.5
ENST00000512653.5
ENST00000344730.7
ABL proto-oncogene 2, non-receptor tyrosine kinase
chr20_+_44401222 0.48 ENST00000316099.9
hepatocyte nuclear factor 4 alpha
chr11_-_65662780 0.40 ENST00000534283.1
ENST00000527749.5
ENST00000533187.5
ENST00000525693.5
ENST00000534558.5
ENST00000532879.5
ENST00000406246.8
ENST00000532999.5
RELA proto-oncogene, NF-kB subunit
chrX_-_49079702 0.32 ENST00000636049.1
ENST00000474053.6
ENST00000635003.1
WD repeat domain 45

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.4 50.5 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
5.9 17.7 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
5.6 16.8 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
4.9 14.6 GO:1901388 regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
4.3 12.9 GO:1902905 positive regulation of fibril organization(GO:1902905)
3.9 23.6 GO:0007296 vitellogenesis(GO:0007296)
3.1 15.6 GO:0015862 uridine transport(GO:0015862)
2.7 11.0 GO:1902463 protein localization to cell leading edge(GO:1902463)
2.6 12.8 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
2.5 10.2 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
2.4 11.9 GO:1902513 regulation of organelle transport along microtubule(GO:1902513)
2.3 13.6 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
2.2 13.4 GO:0002036 regulation of L-glutamate transport(GO:0002036)
2.2 10.8 GO:0044111 development involved in symbiotic interaction(GO:0044111)
2.1 6.3 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
1.9 19.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
1.9 5.8 GO:0097252 negative regulation of helicase activity(GO:0051097) oligodendrocyte apoptotic process(GO:0097252)
1.9 5.7 GO:0042946 glucoside transport(GO:0042946)
1.7 13.4 GO:0030091 protein repair(GO:0030091)
1.6 20.9 GO:0021796 cerebral cortex regionalization(GO:0021796)
1.6 6.2 GO:0048388 endosomal lumen acidification(GO:0048388)
1.5 7.7 GO:0006741 NADP biosynthetic process(GO:0006741)
1.5 6.0 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
1.5 8.8 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
1.4 11.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
1.4 10.8 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
1.3 23.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.3 6.4 GO:1902896 terminal web assembly(GO:1902896)
1.3 17.8 GO:0060712 spongiotrophoblast layer development(GO:0060712)
1.2 13.4 GO:0035092 sperm chromatin condensation(GO:0035092)
1.2 21.9 GO:0016540 protein autoprocessing(GO:0016540)
1.2 10.8 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
1.2 3.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.2 9.3 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
1.1 119.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
1.0 5.2 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
1.0 8.0 GO:0044206 pyrimidine ribonucleotide salvage(GO:0010138) pyrimidine nucleotide salvage(GO:0032262) UMP salvage(GO:0044206)
0.9 13.0 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.8 7.0 GO:0001866 NK T cell proliferation(GO:0001866)
0.8 7.8 GO:0002934 desmosome organization(GO:0002934)
0.7 2.9 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.7 38.2 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.7 2.1 GO:0036233 glycine import(GO:0036233)
0.6 14.5 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.6 4.4 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.6 8.8 GO:2000680 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.6 1.8 GO:1903028 positive regulation of opsonization(GO:1903028)
0.6 5.2 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.6 10.7 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.6 5.1 GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.5 12.8 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.5 3.9 GO:0060025 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) regulation of synaptic activity(GO:0060025)
0.5 4.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.5 6.9 GO:0051014 actin filament severing(GO:0051014)
0.4 10.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592) megakaryocyte development(GO:0035855)
0.4 5.3 GO:2000650 negative regulation of sodium ion transmembrane transport(GO:1902306) negative regulation of sodium ion transmembrane transporter activity(GO:2000650) positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.4 2.6 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.4 2.6 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.4 11.3 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.4 11.6 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.4 0.8 GO:0032899 regulation of neurotrophin production(GO:0032899) negative regulation of neurotrophin production(GO:0032900)
0.4 7.1 GO:0001765 membrane raft assembly(GO:0001765)
0.4 29.1 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.4 3.8 GO:0061635 regulation of protein complex stability(GO:0061635)
0.4 2.5 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.4 14.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.4 2.1 GO:0097278 complement-dependent cytotoxicity(GO:0097278) regulation of complement-dependent cytotoxicity(GO:1903659)
0.3 2.1 GO:0070383 cytidine to uridine editing(GO:0016554) DNA cytosine deamination(GO:0070383)
0.3 8.3 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.3 8.1 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.3 16.9 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.3 3.5 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 8.5 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.2 19.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 13.9 GO:0030224 monocyte differentiation(GO:0030224)
0.2 2.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.2 10.0 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.2 0.7 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.2 23.3 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.2 0.9 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.2 13.9 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 17.5 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.2 6.8 GO:0034629 cellular protein complex localization(GO:0034629)
0.2 11.8 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.2 27.3 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.2 0.5 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.1 1.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.7 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.1 4.8 GO:0006458 'de novo' protein folding(GO:0006458)
0.1 12.4 GO:0051225 spindle assembly(GO:0051225)
0.1 6.2 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 1.4 GO:0051683 establishment of Golgi localization(GO:0051683)
0.1 3.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 1.1 GO:0035878 nail development(GO:0035878)
0.1 4.0 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 1.7 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437)
0.1 0.8 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 2.6 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 3.5 GO:0006305 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.0 15.8 GO:0007411 axon guidance(GO:0007411)
0.0 4.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 1.4 GO:0060512 prostate gland morphogenesis(GO:0060512)
0.0 12.9 GO:0006469 negative regulation of protein kinase activity(GO:0006469)
0.0 7.6 GO:0051028 mRNA transport(GO:0051028)
0.0 2.8 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 31.3 GO:0045087 innate immune response(GO:0045087)
0.0 7.4 GO:0006457 protein folding(GO:0006457)
0.0 11.6 GO:0000226 microtubule cytoskeleton organization(GO:0000226)
0.0 2.3 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 3.6 GO:0007179 transforming growth factor beta receptor signaling pathway(GO:0007179)
0.0 0.2 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.1 GO:0002251 organ or tissue specific immune response(GO:0002251)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
11.3 34.0 GO:0034515 proteasome storage granule(GO:0034515)
4.9 14.6 GO:1990917 sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
4.6 50.5 GO:0005638 lamin filament(GO:0005638)
3.6 10.8 GO:0071148 TEAD-1-YAP complex(GO:0071148)
3.6 10.7 GO:0033565 ESCRT-0 complex(GO:0033565)
3.0 20.9 GO:0097451 glial limiting end-foot(GO:0097451)
2.4 26.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
2.3 11.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
2.1 6.4 GO:0044393 microspike(GO:0044393)
2.1 27.0 GO:0031209 SCAR complex(GO:0031209)
1.6 22.1 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
1.5 10.8 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
1.4 12.4 GO:0070652 HAUS complex(GO:0070652)
1.4 17.7 GO:0005915 zonula adherens(GO:0005915)
1.3 15.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
1.2 18.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
1.1 17.5 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
1.0 11.0 GO:0032593 insulin-responsive compartment(GO:0032593)
1.0 11.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
1.0 6.8 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.9 26.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.9 14.6 GO:0005838 proteasome regulatory particle(GO:0005838)
0.9 6.8 GO:0005827 polar microtubule(GO:0005827)
0.8 14.5 GO:0036020 endolysosome membrane(GO:0036020)
0.7 14.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.7 8.1 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.7 8.8 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.7 6.0 GO:0070765 gamma-secretase complex(GO:0070765)
0.6 13.6 GO:0031045 dense core granule(GO:0031045)
0.6 11.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.6 6.6 GO:0097413 Lewy body(GO:0097413)
0.4 23.9 GO:0031430 M band(GO:0031430)
0.4 3.8 GO:0044754 autolysosome(GO:0044754)
0.4 17.1 GO:0043034 costamere(GO:0043034)
0.3 38.2 GO:0031985 Golgi cisterna(GO:0031985)
0.3 7.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.3 6.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.3 7.8 GO:0030057 desmosome(GO:0030057)
0.3 21.0 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.2 13.9 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.2 23.7 GO:0042734 presynaptic membrane(GO:0042734)
0.2 5.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.2 0.5 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.2 8.5 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.2 17.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 7.8 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 12.8 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 16.5 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 8.8 GO:0035580 specific granule lumen(GO:0035580)
0.1 5.3 GO:0005771 multivesicular body(GO:0005771)
0.1 9.4 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.8 GO:0005610 laminin-5 complex(GO:0005610)
0.1 38.2 GO:0005819 spindle(GO:0005819)
0.1 10.0 GO:0005643 nuclear pore(GO:0005643)
0.1 3.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 1.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 8.2 GO:0016363 nuclear matrix(GO:0016363)
0.1 8.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.9 GO:0030056 hemidesmosome(GO:0030056)
0.1 22.0 GO:0005874 microtubule(GO:0005874)
0.1 6.2 GO:0031902 late endosome membrane(GO:0031902)
0.1 11.9 GO:0005802 trans-Golgi network(GO:0005802)
0.1 1.7 GO:0005859 muscle myosin complex(GO:0005859)
0.1 3.5 GO:0015030 Cajal body(GO:0015030)
0.0 10.8 GO:0005681 spliceosomal complex(GO:0005681)
0.0 1.4 GO:0016592 mediator complex(GO:0016592)
0.0 9.5 GO:0031965 nuclear membrane(GO:0031965)
0.0 12.8 GO:0016604 nuclear body(GO:0016604)
0.0 8.6 GO:0019866 organelle inner membrane(GO:0019866)
0.0 2.5 GO:0016605 PML body(GO:0016605)
0.0 2.6 GO:0042383 sarcolemma(GO:0042383)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 14.6 GO:0002135 CTP binding(GO:0002135)
3.2 19.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
3.0 12.1 GO:0001512 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
2.8 11.1 GO:0043273 CTPase activity(GO:0043273)
2.7 13.4 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
2.5 10.2 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
2.2 23.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
2.2 10.8 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.9 5.7 GO:0042947 glucoside transmembrane transporter activity(GO:0042947)
1.8 5.5 GO:0052836 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
1.7 16.8 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
1.7 11.6 GO:0005134 interleukin-2 receptor binding(GO:0005134)
1.6 6.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
1.5 7.7 GO:0004473 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
1.4 13.6 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) protein phosphatase 2B binding(GO:0030346)
1.3 37.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.3 19.2 GO:0004017 adenylate kinase activity(GO:0004017)
1.3 18.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.3 17.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
1.2 49.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.2 19.6 GO:0030215 semaphorin receptor binding(GO:0030215)
1.2 11.8 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
1.2 3.5 GO:0008859 exoribonuclease II activity(GO:0008859)
1.1 53.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
1.0 4.8 GO:0061649 ubiquitinated histone binding(GO:0061649)
1.0 30.6 GO:0042288 MHC class I protein binding(GO:0042288)
0.8 15.6 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.8 14.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.8 12.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.7 4.8 GO:0048408 epidermal growth factor binding(GO:0048408)
0.7 17.7 GO:0045295 gamma-catenin binding(GO:0045295)
0.7 2.6 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.6 5.8 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.6 8.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.6 17.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.6 6.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.5 2.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.4 13.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.4 37.6 GO:0097110 scaffold protein binding(GO:0097110)
0.4 11.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.4 5.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.4 5.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.3 8.8 GO:0070064 proline-rich region binding(GO:0070064)
0.3 6.2 GO:0001056 RNA polymerase III activity(GO:0001056)
0.3 2.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 13.9 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 12.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.2 9.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 4.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 3.9 GO:0003680 AT DNA binding(GO:0003680)
0.2 14.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 2.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 4.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 9.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 10.0 GO:0008536 Ran GTPase binding(GO:0008536)
0.2 4.0 GO:0097493 S100 protein binding(GO:0044548) structural molecule activity conferring elasticity(GO:0097493)
0.2 2.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 0.8 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.2 3.8 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 29.4 GO:0008201 heparin binding(GO:0008201)
0.2 10.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 3.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 6.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 4.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 8.0 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.1 3.5 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 1.1 GO:0038132 neuregulin binding(GO:0038132)
0.1 13.3 GO:0051082 unfolded protein binding(GO:0051082)
0.1 33.3 GO:0003924 GTPase activity(GO:0003924)
0.1 4.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 10.3 GO:0017124 SH3 domain binding(GO:0017124)
0.1 14.0 GO:0000287 magnesium ion binding(GO:0000287)
0.0 39.2 GO:0005198 structural molecule activity(GO:0005198)
0.0 6.3 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 3.7 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 1.8 GO:0043531 ADP binding(GO:0043531)
0.0 4.4 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 3.1 GO:0019905 syntaxin binding(GO:0019905)
0.0 2.6 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 14.9 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.0 2.5 GO:0005178 integrin binding(GO:0005178)
0.0 1.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 32.1 PID ARF 3PATHWAY Arf1 pathway
0.6 47.1 PID RHOA PATHWAY RhoA signaling pathway
0.6 17.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.6 52.5 PID ILK PATHWAY Integrin-linked kinase signaling
0.4 23.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.4 21.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.4 28.7 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.3 20.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.3 37.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.3 6.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.3 6.8 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.3 10.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.2 18.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 6.8 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 9.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.2 12.8 PID HNF3A PATHWAY FOXA1 transcription factor network
0.2 22.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 3.8 PID IL1 PATHWAY IL1-mediated signaling events
0.1 4.4 PID RAS PATHWAY Regulation of Ras family activation
0.1 1.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 5.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 1.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 10.8 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 2.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.1 2.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 8.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 11.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 4.0 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.8 PID ATM PATHWAY ATM pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 118.2 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
1.6 45.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
1.5 32.1 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
1.0 50.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.9 8.0 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.9 12.9 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.8 14.6 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.8 12.8 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.8 11.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.6 6.8 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.5 16.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.5 10.7 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.4 23.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.4 11.0 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.4 10.8 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.4 15.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.3 14.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.3 6.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.2 19.1 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.2 14.9 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 7.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 3.9 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.2 6.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.2 13.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.2 28.7 REACTOME TRANSLATION Genes involved in Translation
0.2 4.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.2 2.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 2.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 5.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 10.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 2.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 9.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 2.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 1.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.5 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 2.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor