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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for BARHL1

Z-value: 11.65

Motif logo

Transcription factors associated with BARHL1

Gene Symbol Gene ID Gene Info
ENSG00000125492.10 BARHL1

Activity profile of BARHL1 motif

Sorted Z-values of BARHL1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of BARHL1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_-_108058361 59.27 ENST00000398258.7
CD47 molecule
chr3_-_185923893 45.69 ENST00000259043.11
transformer 2 beta homolog
chr8_-_63026179 44.67 ENST00000677919.1
gamma-glutamyl hydrolase
chr4_+_106315534 42.76 ENST00000510207.5
aminoacyl tRNA synthetase complex interacting multifunctional protein 1
chr14_+_55661272 40.33 ENST00000555573.5
kinectin 1
chr15_+_41286011 40.25 ENST00000661438.1
novel protein
chr18_-_36122110 39.75 ENST00000586829.1
solute carrier family 39 member 6
chr5_-_69369257 38.74 ENST00000509462.5
TATA-box binding protein associated factor 9
chr8_-_27838034 37.41 ENST00000522944.5
PDZ binding kinase
chr15_-_60398733 36.15 ENST00000559818.6
annexin A2
chr17_-_42018488 36.14 ENST00000589773.5
ENST00000674214.1
DnaJ heat shock protein family (Hsp40) member C7
chr13_+_30422487 35.42 ENST00000638137.1
ENST00000635918.2
ubiquitin conjugating enzyme E2 L5
chr17_-_8210203 34.91 ENST00000578549.5
ENST00000582368.5
aurora kinase B
chr12_-_110445540 33.74 ENST00000547365.1
actin related protein 2/3 complex subunit 3
chr13_-_23433735 33.52 ENST00000423156.2
ENST00000683210.1
ENST00000682775.1
ENST00000684497.1
ENST00000682944.1
ENST00000683489.1
ENST00000684385.1
ENST00000683680.1
sacsin molecular chaperone
chr12_-_119804298 32.99 ENST00000678652.1
ENST00000678494.1
citron rho-interacting serine/threonine kinase
chr3_+_133805789 32.65 ENST00000678299.1
SRP receptor subunit beta
chr8_-_80029904 32.62 ENST00000521434.5
ENST00000519120.1
ENST00000520946.1
mitochondrial ribosomal protein S28
chr11_-_11353241 32.49 ENST00000528848.3
casein kinase 2 alpha 3
chr18_+_657637 32.16 ENST00000323274.15
thymidylate synthetase
chr18_+_657734 32.00 ENST00000323250.9
ENST00000323224.7
thymidylate synthetase
chr22_+_41621977 31.86 ENST00000405506.2
X-ray repair cross complementing 6
chr12_-_119803383 31.09 ENST00000392520.2
ENST00000678677.1
ENST00000679249.1
ENST00000676849.1
citron rho-interacting serine/threonine kinase
chr17_-_42136431 30.90 ENST00000552162.5
ENST00000550504.5
RAB5C, member RAS oncogene family
chr3_+_184300564 30.70 ENST00000435761.5
ENST00000439383.5
proteasome 26S subunit, non-ATPase 2
chr17_-_75154534 30.10 ENST00000356033.8
Jupiter microtubule associated homolog 1
chr2_-_175181663 28.25 ENST00000392541.3
ENST00000284727.9
ENST00000409194.5
ATP synthase membrane subunit c locus 3
chr2_+_86199355 27.80 ENST00000254644.12
ENST00000605125.5
ENST00000337109.9
ENST00000409180.1
mitochondrial ribosomal protein L35
chr1_+_165895564 27.79 ENST00000469256.6
uridine-cytidine kinase 2
chr20_-_56392131 27.78 ENST00000422322.5
ENST00000371356.6
ENST00000451915.1
ENST00000347343.6
ENST00000395911.5
ENST00000395915.8
ENST00000395907.5
ENST00000441357.5
ENST00000456249.5
ENST00000420474.5
ENST00000395914.5
ENST00000312783.10
ENST00000395913.7
aurora kinase A
chr3_+_128794748 27.32 ENST00000674589.1
RAB7A, member RAS oncogene family
chr1_-_17045219 27.16 ENST00000491274.5
succinate dehydrogenase complex iron sulfur subunit B
chr8_+_54135203 26.82 ENST00000260102.9
ENST00000519831.5
mitochondrial ribosomal protein L15
chr17_-_58353069 26.69 ENST00000580947.1
SPT4 homolog, DSIF elongation factor subunit
chr4_-_173334385 26.67 ENST00000446922.6
high mobility group box 2
chrX_-_77634229 26.62 ENST00000675732.1
ATRX chromatin remodeler
chr6_-_13814490 26.53 ENST00000379170.8
mitochondrial calcium uniporter regulator 1
chr14_+_77708076 26.51 ENST00000238688.9
ENST00000557342.6
ENST00000557623.5
ENST00000557431.5
ENST00000556831.5
ENST00000556375.5
ENST00000553981.1
SRA stem-loop interacting RNA binding protein
chr5_+_69167117 26.44 ENST00000506572.5
ENST00000256442.10
cyclin B1
chr1_-_92075441 26.18 ENST00000596516.2
SET like protein
chr3_+_172039556 26.17 ENST00000415807.7
ENST00000421757.5
fibronectin type III domain containing 3B
chr11_+_35180342 25.85 ENST00000639002.1
CD44 molecule (Indian blood group)
chr5_+_163460650 25.20 ENST00000358715.3
hyaluronan mediated motility receptor
chr1_+_165895583 25.10 ENST00000470820.1
uridine-cytidine kinase 2
chr5_+_172958729 24.97 ENST00000519974.5
ENST00000521476.5
ribosomal protein L26 like 1
chr8_+_11809135 24.89 ENST00000528643.5
ENST00000525777.5
farnesyl-diphosphate farnesyltransferase 1
chr12_-_76068933 24.71 ENST00000552056.5
nucleosome assembly protein 1 like 1
chr11_+_114439424 24.66 ENST00000544196.5
ENST00000265881.10
ENST00000539754.5
ENST00000539275.5
RNA exonuclease 2
chr4_+_106315689 24.12 ENST00000358008.7
aminoacyl tRNA synthetase complex interacting multifunctional protein 1
chr15_-_59657494 24.07 ENST00000396063.5
ENST00000396060.7
ENST00000396064.7
ENST00000484743.5
ENST00000559706.1
general transcription factor IIA subunit 2
chr7_-_123557679 23.98 ENST00000677264.1
ENST00000471770.5
ENST00000676730.1
ENST00000677391.1
ENST00000677251.1
ENST00000470123.2
ENST00000679163.1
ENST00000676614.1
ENST00000378795.9
ENST00000676516.1
ENST00000355749.7
ENST00000678090.1
NADH:ubiquinone oxidoreductase subunit A5
chr17_+_68525795 23.97 ENST00000592800.5
protein kinase cAMP-dependent type I regulatory subunit alpha
chr15_+_78540405 23.96 ENST00000560217.5
ENST00000559082.5
ENST00000559948.5
ENST00000413382.6
ENST00000559146.5
ENST00000044462.12
ENST00000558281.5
proteasome 20S subunit alpha 4
chr1_+_220094086 23.95 ENST00000366922.3
isoleucyl-tRNA synthetase 2, mitochondrial
chr4_+_112637456 23.88 ENST00000505034.5
ENST00000324052.10
La ribonucleoprotein 7, transcriptional regulator
chr11_+_102112445 23.87 ENST00000524575.5
Yes1 associated transcriptional regulator
chr1_-_74732997 23.76 ENST00000370872.7
ENST00000370871.7
ENST00000340866.10
ENST00000370870.5
crystallin zeta
chr11_+_35180279 23.74 ENST00000531873.5
CD44 molecule (Indian blood group)
chr2_+_27212866 23.70 ENST00000419744.1
all-trans retinoic acid induced differentiation factor
chr17_-_40417873 23.65 ENST00000423485.6
DNA topoisomerase II alpha
chr1_-_246193727 23.53 ENST00000391836.3
SET and MYND domain containing 3
chr1_+_13060769 23.51 ENST00000617807.3
heterogeneous nuclear ribonucleoprotein C like 3
chr4_-_142305935 23.25 ENST00000511838.5
inositol polyphosphate-4-phosphatase type II B
chr6_-_79234713 22.85 ENST00000620514.1
high mobility group nucleosomal binding domain 3
chr3_-_197226351 22.72 ENST00000656428.1
discs large MAGUK scaffold protein 1
chr5_+_163460623 22.62 ENST00000393915.9
ENST00000432118.6
hyaluronan mediated motility receptor
chrX_+_70290077 22.23 ENST00000374403.4
kinesin family member 4A
chr10_-_93482326 22.20 ENST00000359263.9
myoferlin
chr5_+_160421847 22.10 ENST00000352433.10
ENST00000517480.1
ENST00000520452.5
ENST00000393964.1
PTTG1 regulator of sister chromatid separation, securin
chr16_+_51553436 22.09 ENST00000565308.2
heterogeneous nuclear ribonucleoprotein A1 pseudogene 48
chr16_-_58129358 21.99 ENST00000565880.1
ENST00000262498.8
cilia and flagella associated protein 20
chr15_+_40161003 21.88 ENST00000412359.7
ENST00000287598.11
BUB1 mitotic checkpoint serine/threonine kinase B
chr5_-_179617581 21.85 ENST00000523449.5
heterogeneous nuclear ribonucleoprotein H1
chr18_+_58149314 21.81 ENST00000435432.6
ENST00000357895.9
ENST00000586263.5
NEDD4 like E3 ubiquitin protein ligase
chr12_+_107685759 21.80 ENST00000412830.8
ENST00000547995.5
PWP1 homolog, endonuclein
chr8_-_100950549 21.80 ENST00000395951.7
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta
chr19_+_47130782 21.76 ENST00000597808.5
ENST00000413379.7
ENST00000600706.5
ENST00000270225.12
ENST00000598840.5
ENST00000600753.1
ENST00000392776.3
SUMO1 activating enzyme subunit 1
chr1_+_165827574 21.60 ENST00000367879.9
uridine-cytidine kinase 2
chr11_-_47426419 21.43 ENST00000298852.8
ENST00000530912.5
ENST00000619920.4
proteasome 26S subunit, ATPase 3
chr5_-_43557689 21.42 ENST00000338972.8
ENST00000511321.5
ENST00000515338.1
poly(A) binding protein interacting protein 1
chr20_+_25407657 21.35 ENST00000262460.5
GINS complex subunit 1
chr2_-_32011001 21.07 ENST00000404530.6
mediator of cell motility 1
chrX_-_15493234 21.04 ENST00000380420.10
pirin
chr12_-_71157992 20.97 ENST00000247829.8
tetraspanin 8
chr9_+_36572854 20.95 ENST00000543751.5
ENST00000536860.5
ENST00000541717.4
ENST00000536329.5
ENST00000536987.5
ENST00000298048.7
ENST00000495529.5
ENST00000545008.5
maternal embryonic leucine zipper kinase
chr4_-_121823843 20.95 ENST00000274026.10
cyclin A2
chr13_-_23433676 20.93 ENST00000682547.1
ENST00000455470.6
ENST00000382292.9
sacsin molecular chaperone
chr15_+_66505289 20.90 ENST00000565627.5
ENST00000564179.5
ENST00000307897.10
zwilch kinetochore protein
chr11_-_14499833 20.84 ENST00000249923.7
ENST00000529866.5
COPI coat complex subunit beta 1
chr8_-_108248700 20.63 ENST00000220849.10
ENST00000678937.1
ENST00000678901.1
ENST00000678243.1
ENST00000677674.1
ENST00000521297.2
ENST00000677272.1
ENST00000522352.6
ENST00000678042.1
ENST00000519627.2
ENST00000521440.6
ENST00000678773.1
ENST00000676698.1
ENST00000518345.2
ENST00000677447.1
ENST00000676548.1
ENST00000519030.6
ENST00000518442.5
eukaryotic translation initiation factor 3 subunit E
chr3_+_172750682 20.47 ENST00000232458.9
ENST00000540509.5
epithelial cell transforming 2
chr6_-_149746497 20.42 ENST00000367404.8
ENST00000340413.7
ENST00000543637.1
nucleoporin 43
chr7_+_76303547 20.37 ENST00000429938.1
heat shock protein family B (small) member 1
chr12_+_69239592 20.35 ENST00000456847.7
ENST00000266679.8
cleavage and polyadenylation specific factor 6
chr14_+_35292429 20.31 ENST00000555764.5
ENST00000556506.1
proteasome 20S subunit alpha 6
chr15_-_59657468 20.21 ENST00000396061.5
general transcription factor IIA subunit 2
chrX_+_120604199 20.21 ENST00000371315.3
MCTS1 re-initiation and release factor
chr2_+_161308407 20.13 ENST00000409682.8
proteasome 26S subunit, non-ATPase 14
chr5_+_141182369 20.12 ENST00000609684.3
ENST00000625044.1
ENST00000623407.1
ENST00000623884.1
protocadherin beta 16
novel transcript
chr12_-_71157872 19.96 ENST00000546561.2
tetraspanin 8
chr15_+_66504959 19.92 ENST00000535141.6
ENST00000613446.4
ENST00000446801.6
zwilch kinetochore protein
chr1_+_53014926 19.87 ENST00000430330.6
ENST00000408941.7
ENST00000478274.6
ENST00000484100.5
ENST00000435345.6
ENST00000488965.1
sterol carrier protein 2
chr1_+_51617079 19.73 ENST00000447887.5
ENST00000428468.6
ENST00000453295.5
oxysterol binding protein like 9
chr2_-_150487658 19.72 ENST00000375734.6
ENST00000263895.9
ENST00000454202.5
Rho family GTPase 3
chr12_+_103965863 19.66 ENST00000392872.8
ENST00000537100.5
thymine DNA glycosylase
chr10_+_5446601 19.56 ENST00000449083.5
ENST00000380359.3
neuroepithelial cell transforming 1
chr11_-_47642519 19.38 ENST00000302503.8
ENST00000530428.1
mitochondrial carrier 2
chr8_-_80029826 19.37 ENST00000519386.5
mitochondrial ribosomal protein S28
chr9_-_124415421 19.36 ENST00000259457.8
ENST00000441097.1
proteasome 20S subunit beta 7
chr12_+_69585434 19.36 ENST00000299300.11
ENST00000544368.6
chaperonin containing TCP1 subunit 2
chr9_+_89311187 19.32 ENST00000314355.7
CDC28 protein kinase regulatory subunit 2
chr14_+_34993240 19.23 ENST00000677647.1
signal recognition particle 54
chr14_+_20455968 19.19 ENST00000438886.1
apurinic/apyrimidinic endodeoxyribonuclease 1
chr3_-_64023986 19.09 ENST00000394431.6
proteasome 26S subunit, non-ATPase 6
chr18_-_36798482 19.09 ENST00000590258.2
tubulin polyglutamylase complex subunit 2
chr7_+_99325857 19.08 ENST00000638617.1
ENST00000262942.10
novel protein, ARPC1A and ARPC1B readthrough
actin related protein 2/3 complex subunit 1A
chr7_+_2354810 19.02 ENST00000360876.9
ENST00000413917.5
ENST00000397011.2
eukaryotic translation initiation factor 3 subunit B
chr12_+_56041893 18.99 ENST00000552361.1
ENST00000646449.2
ribosomal protein S26
chr15_+_65550819 18.88 ENST00000569894.5
3-hydroxyacyl-CoA dehydratase 3
chr7_-_88226965 18.74 ENST00000490437.5
ENST00000431660.5
sorcin
chr7_+_16661182 18.72 ENST00000446596.5
ENST00000452975.6
ENST00000438834.5
basic leucine zipper and W2 domains 2
chr1_-_70205531 18.58 ENST00000370952.4
leucine rich repeat containing 40
chr9_+_113275642 18.54 ENST00000374199.9
ENST00000374198.5
pre-mRNA processing factor 4
chr10_+_13586933 18.46 ENST00000417658.5
ENST00000378572.8
ENST00000320054.4
pre-mRNA processing factor 18
chr8_-_27837765 18.42 ENST00000521226.2
ENST00000301905.9
PDZ binding kinase
chr10_-_93482194 18.30 ENST00000358334.9
ENST00000371488.3
myoferlin
chr9_-_146140 18.29 ENST00000475990.5
COBW domain containing 1
chr2_+_171922442 18.22 ENST00000264108.5
histone acetyltransferase 1
chr7_+_80133830 18.21 ENST00000648098.1
ENST00000648476.1
ENST00000648412.1
ENST00000648953.1
ENST00000648306.1
ENST00000648832.1
ENST00000648877.1
ENST00000442586.2
ENST00000649487.1
ENST00000649267.1
G protein subunit alpha i1
chr6_+_138404206 18.17 ENST00000607197.6
ENST00000367697.7
heme binding protein 2
chr7_-_88226987 18.00 ENST00000394641.7
sorcin
chr6_+_63521738 17.87 ENST00000648894.1
ENST00000639568.2
protein tyrosine phosphatase 4A1
chrX_+_120604084 17.76 ENST00000371317.10
MCTS1 re-initiation and release factor
chr5_-_77776321 17.75 ENST00000380377.9
tubulin folding cofactor A
chr20_-_44504850 17.71 ENST00000411544.5
serine incorporator 3
chr15_+_80072559 17.67 ENST00000560228.5
ENST00000559835.5
ENST00000559775.5
ENST00000558688.5
ENST00000560392.5
ENST00000560976.5
ENST00000558272.5
ENST00000558390.5
zinc finger AN1-type containing 6
chr2_+_169798841 17.61 ENST00000260956.9
ENST00000417292.5
small RNA binding exonuclease protection factor La
chr20_-_49188360 17.54 ENST00000371828.7
ENST00000340954.11
ENST00000347458.9
ENST00000360426.8
ENST00000371792.5
ENST00000371802.5
ENST00000437404.2
staufen double-stranded RNA binding protein 1
chr3_-_196082078 17.52 ENST00000360110.9
ENST00000392396.7
ENST00000420415.5
transferrin receptor
chr21_-_29073565 17.52 ENST00000431234.1
ENST00000286788.9
ENST00000540844.5
chaperonin containing TCP1 subunit 8
chr8_+_11803012 17.39 ENST00000528812.5
ENST00000622850.2
farnesyl-diphosphate farnesyltransferase 1
chr6_-_85644043 17.38 ENST00000678930.1
ENST00000678355.1
synaptotagmin binding cytoplasmic RNA interacting protein
chr7_+_73692596 17.37 ENST00000453316.1
BUD23 rRNA methyltransferase and ribosome maturation factor
chr3_-_32502783 17.37 ENST00000205636.4
CKLF like MARVEL transmembrane domain containing 6
chr5_+_168486462 17.37 ENST00000231572.8
ENST00000626454.1
arginyl-tRNA synthetase 1
chr13_-_37105664 17.31 ENST00000379800.4
casein kinase 1 alpha 1 like
chr20_+_37777262 17.31 ENST00000373469.1
catenin beta like 1
chr3_-_133661896 17.28 ENST00000260810.10
DNA topoisomerase II binding protein 1
chr20_+_11917859 17.20 ENST00000618296.4
ENST00000378226.7
BTB domain containing 3
chr17_+_37491464 17.19 ENST00000613659.1
dual specificity phosphatase 14
chr19_+_49676140 17.19 ENST00000527382.5
ENST00000528623.5
protein arginine methyltransferase 1
chr5_-_135399863 17.13 ENST00000510038.1
ENST00000304332.8
macroH2A.1 histone
chr7_-_97872420 17.12 ENST00000444334.5
ENST00000422745.5
ENST00000451771.5
ENST00000175506.8
asparagine synthetase (glutamine-hydrolyzing)
chr1_+_40988513 17.07 ENST00000649215.1
CTP synthase 1
chr1_-_45522870 17.01 ENST00000424390.2
peroxiredoxin 1
chr3_+_128726130 16.95 ENST00000676425.1
ENST00000675864.1
RAB7A, member RAS oncogene family
chr4_+_56435730 16.85 ENST00000514888.5
ENST00000264221.6
ENST00000505164.5
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
chr4_-_142305826 16.82 ENST00000514525.1
inositol polyphosphate-4-phosphatase type II B
chr6_-_8102046 16.81 ENST00000488226.2
eukaryotic translation elongation factor 1 epsilon 1
chr19_+_39655907 16.79 ENST00000392051.4
galectin 16
chr6_+_70667863 16.78 ENST00000370455.8
small ArfGAP 1
chr3_-_146528750 16.74 ENST00000483300.5
phospholipid scramblase 1
chr1_-_193106048 16.71 ENST00000367440.3
glutaredoxin 2
chr11_-_14499803 16.70 ENST00000439561.7
ENST00000534234.5
COPI coat complex subunit beta 1
chr12_+_68686951 16.68 ENST00000378905.6
ENST00000229179.9
nucleoporin 107
chr6_-_79234619 16.63 ENST00000344726.9
ENST00000275036.11
high mobility group nucleosomal binding domain 3
chr1_-_108192818 16.50 ENST00000370041.4
solute carrier family 25 member 24
chr7_+_832470 16.47 ENST00000401592.6
Sad1 and UNC84 domain containing 1
chrX_+_19355582 16.40 ENST00000379804.1
pyruvate dehydrogenase E1 subunit alpha 1
chr13_-_30464234 16.39 ENST00000399489.5
ENST00000339872.8
high mobility group box 1
chr3_-_57597443 16.30 ENST00000463880.1
ADP ribosylation factor 4
chrX_+_155881306 16.21 ENST00000286448.12
ENST00000262640.11
ENST00000460621.6
vesicle associated membrane protein 7
chr11_-_33717409 16.21 ENST00000651485.1
CD59 molecule (CD59 blood group)
chr9_+_69145463 16.19 ENST00000636438.1
tight junction protein 2
chr3_-_149576203 16.19 ENST00000472417.1
WW domain containing transcription regulator 1
chr16_-_66830903 16.15 ENST00000566336.5
ENST00000394074.6
ENST00000563185.6
ENST00000359087.8
ENST00000290810.8
ENST00000379463.6
ENST00000565535.5
NEDD8 activating enzyme E1 subunit 1
chr12_+_53300027 16.14 ENST00000549488.5
MYG1 exonuclease
chr17_+_36486668 16.13 ENST00000617429.5
ENST00000620324.4
ENST00000616269.1
zinc finger HIT-type containing 3
chr17_-_67366562 16.08 ENST00000356126.8
ENST00000357146.4
proteasome 26S subunit, non-ATPase 12
chr4_+_56436131 16.06 ENST00000399688.7
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
chr16_-_23596277 16.05 ENST00000562133.5
ENST00000570319.5
ENST00000007516.8
NADH:ubiquinone oxidoreductase subunit AB1
chr13_+_48037692 16.01 ENST00000258662.3
nudix hydrolase 15
chr8_+_42391895 16.00 ENST00000521158.5
voltage dependent anion channel 3
chr10_-_125816596 15.98 ENST00000368786.5
uroporphyrinogen III synthase
chr9_+_105700953 15.96 ENST00000374688.5
transmembrane protein 38B
chr17_+_75234704 15.95 ENST00000579838.1
nucleoporin 85
chr4_+_112637514 15.91 ENST00000651579.1
La ribonucleoprotein 7, transcriptional regulator
chr20_-_49188323 15.91 ENST00000371856.7
staufen double-stranded RNA binding protein 1
chr11_-_83286328 15.91 ENST00000525503.5
coiled-coil domain containing 90B
chr2_-_224497816 15.89 ENST00000451538.1
cullin 3
chr1_+_171512032 15.88 ENST00000426496.6
proline rich coiled-coil 2C
chr22_-_41690462 15.81 ENST00000648350.1
ENST00000402458.1
small nuclear ribonucleoprotein 13
chr7_+_55951852 15.81 ENST00000285298.9
mitochondrial ribosomal protein S17
chr9_+_69205141 15.79 ENST00000649134.1
ENST00000539225.2
ENST00000650084.1
ENST00000648402.1
tight junction protein 2
chr1_+_225777813 15.75 ENST00000619790.4
ENST00000626563.2
ENST00000304786.12
ENST00000650651.1
ENST00000366839.8
ENST00000651761.1
ENST00000366838.1
signal recognition particle 9
chr2_+_201071984 15.69 ENST00000237889.9
ENST00000433898.5
ENST00000684175.1
ENST00000682325.1
ENST00000454214.1
ENST00000684420.1
NADH:ubiquinone oxidoreductase subunit B3
chr4_-_102828022 15.69 ENST00000502690.5
ubiquitin conjugating enzyme E2 D3
chr7_-_97872120 15.63 ENST00000394309.7
ENST00000414884.1
ENST00000442734.5
asparagine synthetase (glutamine-hydrolyzing)
chr3_-_186806445 15.53 ENST00000418288.5
ENST00000296273.7
replication factor C subunit 4
chr5_-_140691312 15.52 ENST00000438307.6
ENST00000415192.6
ENST00000509087.2
ENST00000675698.1
ENST00000504156.7
ENST00000457527.6
ENST00000307633.7
ENST00000676327.1
ENST00000675851.1
ENST00000675366.1
ENST00000675204.1
ENST00000507746.7
ENST00000431330.7
histidyl-tRNA synthetase 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
19.6 58.9 GO:0007174 epidermal growth factor catabolic process(GO:0007174)
18.6 74.5 GO:0009224 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
16.6 66.4 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
16.0 64.2 GO:0019860 uracil metabolic process(GO:0019860)
14.6 58.3 GO:0002188 translation reinitiation(GO:0002188)
14.2 42.7 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
11.7 46.9 GO:0070981 L-asparagine biosynthetic process(GO:0070981) L-asparagine metabolic process(GO:0070982)
11.2 44.7 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
9.9 49.6 GO:0044111 development involved in symbiotic interaction(GO:0044111)
9.6 28.8 GO:0071283 cellular response to iron(III) ion(GO:0071283)
9.5 66.7 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
9.3 37.1 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
9.3 27.8 GO:1900195 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
9.2 46.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
8.8 26.3 GO:0034476 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
8.2 48.9 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
8.0 8.0 GO:0006529 asparagine biosynthetic process(GO:0006529)
7.8 46.7 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
7.5 22.6 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
7.5 44.8 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
7.4 44.3 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
7.3 21.9 GO:1904908 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
7.0 20.9 GO:0071373 cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373)
6.7 20.0 GO:0036111 very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
6.6 26.3 GO:0007113 endomitotic cell cycle(GO:0007113)
6.5 26.0 GO:0072186 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
6.4 19.2 GO:0097698 telomere maintenance via base-excision repair(GO:0097698)
6.4 25.4 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
6.3 19.0 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
6.3 31.3 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
6.2 18.6 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
6.2 43.3 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
6.2 37.0 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
6.1 30.4 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
6.0 42.0 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
5.9 76.7 GO:0006265 DNA topological change(GO:0006265)
5.9 11.8 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
5.8 23.4 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
5.8 17.4 GO:0070476 RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
5.7 28.3 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
5.6 22.4 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
5.5 16.5 GO:0015866 ADP transport(GO:0015866)
5.5 71.4 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
5.5 21.8 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
5.4 16.2 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595) protein localization to vacuolar membrane(GO:1903778)
5.3 21.2 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938) neuron projection maintenance(GO:1990535)
5.3 15.9 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
5.1 20.4 GO:0099640 axo-dendritic protein transport(GO:0099640)
5.0 25.0 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
5.0 15.0 GO:0006781 succinyl-CoA pathway(GO:0006781)
5.0 29.9 GO:0042780 tRNA 3'-end processing(GO:0042780)
4.9 19.6 GO:0006348 chromatin silencing at telomere(GO:0006348)
4.9 14.7 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
4.9 19.5 GO:0046502 uroporphyrinogen III biosynthetic process(GO:0006780) uroporphyrinogen III metabolic process(GO:0046502)
4.8 19.2 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
4.8 19.0 GO:0051311 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
4.7 65.7 GO:0000492 box C/D snoRNP assembly(GO:0000492)
4.6 64.4 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
4.6 13.7 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
4.6 13.7 GO:1904688 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
4.5 9.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
4.5 31.7 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
4.5 13.5 GO:0036245 cellular response to menadione(GO:0036245)
4.5 9.0 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
4.4 137.9 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
4.4 4.4 GO:0033048 negative regulation of sister chromatid segregation(GO:0033046) negative regulation of mitotic sister chromatid segregation(GO:0033048) negative regulation of chromosome segregation(GO:0051985) negative regulation of mitotic sister chromatid separation(GO:2000816)
4.4 39.8 GO:0071578 zinc II ion transmembrane import(GO:0071578)
4.4 13.2 GO:0060382 regulation of DNA strand elongation(GO:0060382)
4.3 13.0 GO:0033168 conversion of ds siRNA to ss siRNA involved in RNA interference(GO:0033168) conversion of ds siRNA to ss siRNA(GO:0036404)
4.1 8.3 GO:0097327 response to antineoplastic agent(GO:0097327)
4.1 12.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
4.1 37.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
4.0 8.0 GO:0050787 detoxification of mercury ion(GO:0050787)
3.9 35.4 GO:0009249 protein lipoylation(GO:0009249)
3.9 19.5 GO:0051792 medium-chain fatty acid biosynthetic process(GO:0051792)
3.8 11.5 GO:1901420 negative regulation of response to alcohol(GO:1901420)
3.8 7.6 GO:0034729 histone H3-K79 methylation(GO:0034729)
3.8 37.6 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
3.7 11.2 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
3.7 11.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
3.7 7.4 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
3.7 40.5 GO:0042262 DNA protection(GO:0042262)
3.6 10.9 GO:0006097 glyoxylate cycle(GO:0006097)
3.6 14.5 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
3.6 25.1 GO:1903301 positive regulation of hexokinase activity(GO:1903301)
3.5 10.6 GO:0006106 fumarate metabolic process(GO:0006106)
3.5 45.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
3.5 10.5 GO:0019285 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
3.5 27.7 GO:0032020 ISG15-protein conjugation(GO:0032020)
3.5 13.9 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
3.5 10.4 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
3.4 6.8 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
3.4 40.6 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
3.4 10.1 GO:2000866 positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866)
3.4 37.1 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
3.4 30.3 GO:1902416 positive regulation of mRNA binding(GO:1902416)
3.4 26.8 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
3.3 19.9 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
3.3 13.1 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
3.3 9.8 GO:1902594 viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594)
3.2 16.2 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
3.2 9.7 GO:0007518 myoblast fate determination(GO:0007518)
3.2 22.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
3.2 19.0 GO:0075525 viral translational termination-reinitiation(GO:0075525)
3.2 6.3 GO:0002424 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
3.1 34.5 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
3.1 24.8 GO:0007008 outer mitochondrial membrane organization(GO:0007008)
3.1 330.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
3.1 12.3 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
3.1 6.1 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
3.0 33.5 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
3.0 9.1 GO:0048200 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
3.0 15.0 GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
3.0 8.9 GO:1901355 response to rapamycin(GO:1901355)
3.0 5.9 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
3.0 20.7 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
3.0 64.9 GO:0051292 nuclear pore complex assembly(GO:0051292)
2.9 8.8 GO:0016107 sesquiterpenoid metabolic process(GO:0006714) sesquiterpenoid catabolic process(GO:0016107) farnesol metabolic process(GO:0016487) farnesol catabolic process(GO:0016488) regulation of testosterone biosynthetic process(GO:2000224)
2.9 17.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
2.9 8.7 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
2.8 48.4 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
2.8 59.5 GO:0008228 opsonization(GO:0008228)
2.8 36.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
2.8 38.9 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
2.8 11.1 GO:0072683 T cell extravasation(GO:0072683)
2.7 54.9 GO:0006228 UTP biosynthetic process(GO:0006228)
2.7 19.0 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
2.7 13.5 GO:1902896 terminal web assembly(GO:1902896)
2.7 40.3 GO:0000338 protein deneddylation(GO:0000338)
2.7 18.7 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
2.7 34.7 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
2.7 21.4 GO:1902969 mitotic DNA replication(GO:1902969)
2.7 16.0 GO:0015853 adenine transport(GO:0015853)
2.6 23.7 GO:0031584 activation of phospholipase D activity(GO:0031584)
2.6 13.1 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
2.6 20.9 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
2.6 15.7 GO:1990034 calcium ion export from cell(GO:1990034)
2.6 23.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
2.5 7.6 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
2.5 33.0 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
2.5 40.6 GO:0042178 xenobiotic catabolic process(GO:0042178)
2.5 10.1 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
2.5 25.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
2.5 17.6 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
2.5 22.5 GO:0000710 meiotic mismatch repair(GO:0000710)
2.5 32.3 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
2.4 4.9 GO:0015920 lipopolysaccharide transport(GO:0015920)
2.4 29.0 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
2.4 14.4 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
2.4 14.3 GO:0019255 UDP-glucuronate biosynthetic process(GO:0006065) glucose 1-phosphate metabolic process(GO:0019255)
2.4 7.1 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
2.4 9.5 GO:1901873 regulation of post-translational protein modification(GO:1901873)
2.3 35.1 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
2.3 9.3 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
2.3 11.6 GO:1900063 regulation of peroxisome organization(GO:1900063)
2.3 6.9 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
2.3 146.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
2.2 8.9 GO:0007144 female meiosis I(GO:0007144)
2.2 28.8 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
2.2 17.6 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
2.2 13.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
2.2 6.5 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
2.2 8.6 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
2.1 16.7 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
2.1 156.8 GO:0070125 mitochondrial translational elongation(GO:0070125)
2.1 98.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
2.1 6.3 GO:0051182 coenzyme transport(GO:0051182)
2.1 6.2 GO:0006710 androgen catabolic process(GO:0006710)
2.1 10.3 GO:2000542 negative regulation of gastrulation(GO:2000542)
2.0 28.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
2.0 15.8 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
2.0 7.9 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
2.0 3.9 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
2.0 29.5 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
2.0 7.9 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
2.0 7.9 GO:0048194 Golgi vesicle budding(GO:0048194)
2.0 7.9 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
2.0 9.8 GO:1900368 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
1.9 7.7 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
1.9 17.2 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
1.9 13.4 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
1.9 30.4 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
1.9 11.4 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
1.9 5.7 GO:0006740 NADPH regeneration(GO:0006740)
1.9 24.7 GO:0048227 plasma membrane to endosome transport(GO:0048227)
1.9 11.2 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
1.9 14.9 GO:0070900 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
1.8 11.0 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
1.8 25.7 GO:0001778 plasma membrane repair(GO:0001778)
1.8 5.5 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) negative regulation of histone H4-K16 acetylation(GO:2000619)
1.8 7.3 GO:1904045 cellular response to aldosterone(GO:1904045)
1.8 18.2 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
1.8 10.9 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
1.8 3.6 GO:0097252 oligodendrocyte apoptotic process(GO:0097252)
1.8 7.2 GO:0098904 regulation of AV node cell action potential(GO:0098904)
1.8 12.6 GO:0001731 formation of translation preinitiation complex(GO:0001731)
1.8 17.9 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
1.8 33.8 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
1.8 5.3 GO:0014016 neuroblast differentiation(GO:0014016)
1.8 5.3 GO:1903722 regulation of centriole elongation(GO:1903722)
1.8 7.1 GO:0046223 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
1.8 28.4 GO:0006105 succinate metabolic process(GO:0006105)
1.8 5.3 GO:0035720 intraciliary anterograde transport(GO:0035720)
1.8 14.0 GO:0051026 chiasma assembly(GO:0051026)
1.7 10.5 GO:0001880 Mullerian duct regression(GO:0001880)
1.7 5.2 GO:1904387 response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387)
1.7 29.2 GO:0003334 keratinocyte development(GO:0003334)
1.7 8.5 GO:0030242 pexophagy(GO:0030242)
1.7 22.2 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
1.7 3.4 GO:0003162 atrioventricular node development(GO:0003162)
1.7 30.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.7 11.8 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
1.7 58.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
1.7 1.7 GO:2000354 regulation of ovarian follicle development(GO:2000354)
1.7 6.7 GO:1901143 insulin catabolic process(GO:1901143)
1.7 25.0 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.7 19.9 GO:0051451 myoblast migration(GO:0051451)
1.7 8.3 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
1.7 14.9 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
1.6 21.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
1.6 14.7 GO:1904798 positive regulation of core promoter binding(GO:1904798)
1.6 14.6 GO:0042407 cristae formation(GO:0042407)
1.6 27.4 GO:1903753 negative regulation of p38MAPK cascade(GO:1903753)
1.6 4.8 GO:0006447 regulation of translational initiation by iron(GO:0006447)
1.6 25.2 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
1.6 12.5 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
1.5 10.5 GO:0008215 spermine metabolic process(GO:0008215)
1.5 12.0 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
1.5 6.0 GO:0021817 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473)
1.5 10.4 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
1.5 16.3 GO:0006552 leucine catabolic process(GO:0006552)
1.4 11.4 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
1.4 41.4 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
1.4 18.5 GO:0006983 ER overload response(GO:0006983)
1.4 2.8 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242) positive regulation of synaptic vesicle endocytosis(GO:1900244) positive regulation of synaptic vesicle recycling(GO:1903423)
1.4 4.2 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
1.4 12.6 GO:0043382 regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382)
1.4 5.6 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
1.4 15.3 GO:0001682 tRNA 5'-leader removal(GO:0001682)
1.4 2.8 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
1.4 26.0 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
1.4 55.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
1.4 21.8 GO:0051683 establishment of Golgi localization(GO:0051683)
1.4 8.2 GO:0097338 response to clozapine(GO:0097338)
1.4 1.4 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
1.3 5.3 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
1.3 26.7 GO:0000028 ribosomal small subunit assembly(GO:0000028)
1.3 54.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
1.3 5.3 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
1.3 11.9 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
1.3 1.3 GO:0032875 regulation of DNA endoreduplication(GO:0032875)
1.3 6.5 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
1.3 7.8 GO:0046086 adenosine biosynthetic process(GO:0046086)
1.3 5.2 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
1.3 59.2 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
1.3 8.8 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
1.3 2.5 GO:0090234 regulation of kinetochore assembly(GO:0090234)
1.2 3.7 GO:0007538 primary sex determination(GO:0007538)
1.2 13.5 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
1.2 2.5 GO:1990169 detoxification of copper ion(GO:0010273) detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501) stress response to copper ion(GO:1990169)
1.2 17.1 GO:0070987 error-free translesion synthesis(GO:0070987)
1.2 26.7 GO:0030214 hyaluronan catabolic process(GO:0030214)
1.2 9.7 GO:0007068 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
1.2 42.1 GO:0006370 7-methylguanosine mRNA capping(GO:0006370) 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
1.2 10.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.2 3.6 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
1.2 5.9 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
1.2 9.4 GO:0051983 regulation of chromosome segregation(GO:0051983)
1.2 1.2 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
1.2 4.6 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
1.1 4.6 GO:0016584 nucleosome positioning(GO:0016584)
1.1 6.8 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
1.1 15.9 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
1.1 11.3 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
1.1 13.5 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
1.1 3.4 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
1.1 5.6 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
1.1 5.6 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
1.1 3.3 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
1.1 4.4 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
1.1 5.5 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
1.1 10.0 GO:0000012 single strand break repair(GO:0000012)
1.1 14.3 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
1.1 53.7 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
1.1 8.7 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
1.1 5.5 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
1.1 16.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
1.1 8.6 GO:0090151 establishment of protein localization to mitochondrial membrane(GO:0090151)
1.1 2.1 GO:0031393 negative regulation of prostaglandin biosynthetic process(GO:0031393)
1.1 11.7 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
1.1 9.6 GO:2001169 regulation of ATP biosynthetic process(GO:2001169) positive regulation of ATP biosynthetic process(GO:2001171)
1.1 2.1 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) positive regulation of mast cell cytokine production(GO:0032765)
1.1 12.7 GO:0032610 interleukin-1 alpha production(GO:0032610)
1.1 3.2 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
1.1 20.0 GO:0006012 galactose metabolic process(GO:0006012)
1.1 24.2 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
1.1 32.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
1.0 6.3 GO:1904274 tricellular tight junction assembly(GO:1904274)
1.0 11.3 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
1.0 11.3 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
1.0 24.5 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
1.0 5.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
1.0 8.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
1.0 9.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
1.0 4.1 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
1.0 12.1 GO:1903599 positive regulation of mitophagy(GO:1903599)
1.0 15.2 GO:1904355 positive regulation of telomere capping(GO:1904355)
1.0 7.0 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
1.0 14.8 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
1.0 4.9 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
1.0 6.9 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
1.0 4.9 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
1.0 23.5 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
1.0 12.7 GO:0070986 left/right axis specification(GO:0070986)
1.0 63.5 GO:0007062 sister chromatid cohesion(GO:0007062)
1.0 15.6 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
1.0 2.9 GO:0060434 bronchus morphogenesis(GO:0060434)
1.0 14.5 GO:0019184 nonribosomal peptide biosynthetic process(GO:0019184)
1.0 5.8 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
1.0 5.8 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
1.0 4.8 GO:0016139 glycoside catabolic process(GO:0016139)
1.0 2.9 GO:1901253 regulation of intracellular transport of viral material(GO:1901252) negative regulation of intracellular transport of viral material(GO:1901253)
0.9 0.9 GO:0035627 ceramide transport(GO:0035627)
0.9 7.6 GO:0052695 cellular glucuronidation(GO:0052695)
0.9 10.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.9 3.7 GO:0048496 maintenance of organ identity(GO:0048496)
0.9 1.9 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.9 8.4 GO:0071492 response to UV-A(GO:0070141) cellular response to UV-A(GO:0071492)
0.9 32.2 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.9 5.5 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.9 3.7 GO:1990834 autophagic cell death(GO:0048102) response to odorant(GO:1990834)
0.9 6.4 GO:0001887 selenium compound metabolic process(GO:0001887)
0.9 5.4 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.9 3.6 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.9 7.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.9 2.6 GO:1900125 regulation of hyaluronan biosynthetic process(GO:1900125) positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.9 0.9 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.9 3.5 GO:0048388 endosomal lumen acidification(GO:0048388)
0.9 0.9 GO:0060559 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.9 4.3 GO:0042256 mature ribosome assembly(GO:0042256)
0.8 5.0 GO:0006064 glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
0.8 5.0 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.8 7.4 GO:0006089 lactate metabolic process(GO:0006089)
0.8 9.9 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.8 5.7 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.8 4.1 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.8 22.0 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.8 23.5 GO:0006301 postreplication repair(GO:0006301)
0.8 3.2 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
0.8 4.8 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.8 23.1 GO:0015991 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.8 3.2 GO:0031125 rRNA 3'-end processing(GO:0031125) U4 snRNA 3'-end processing(GO:0034475)
0.8 24.5 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.8 7.8 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.8 23.4 GO:0006625 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.8 28.8 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.8 3.9 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.8 1.5 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.8 8.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.8 14.3 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.7 6.0 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.7 3.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.7 3.0 GO:0035803 egg coat formation(GO:0035803)
0.7 3.7 GO:0048537 mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541) Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.7 50.4 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.7 10.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.7 5.0 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.7 21.4 GO:0043489 RNA stabilization(GO:0043489) mRNA stabilization(GO:0048255)
0.7 9.3 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.7 2.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.7 3.5 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.7 23.2 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.7 1.4 GO:0060467 negative regulation of fertilization(GO:0060467)
0.7 2.1 GO:0010710 regulation of collagen catabolic process(GO:0010710)
0.7 3.5 GO:2000210 positive regulation of anoikis(GO:2000210)
0.7 4.1 GO:0051012 microtubule sliding(GO:0051012)
0.7 7.5 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.7 64.3 GO:0006334 nucleosome assembly(GO:0006334)
0.7 3.3 GO:0046628 positive regulation of insulin receptor signaling pathway(GO:0046628)
0.7 4.7 GO:1905066 arterial endothelial cell fate commitment(GO:0060844) canonical Wnt signaling pathway involved in heart development(GO:0061316) canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317) blood vessel lumenization(GO:0072554) positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.7 41.3 GO:0048207 vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.7 5.3 GO:0030091 protein repair(GO:0030091)
0.7 7.9 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.7 8.6 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.6 6.5 GO:0051601 exocyst localization(GO:0051601)
0.6 5.8 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.6 3.8 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.6 1.9 GO:0033210 leptin-mediated signaling pathway(GO:0033210)
0.6 20.1 GO:0006376 mRNA splice site selection(GO:0006376)
0.6 1.9 GO:0044278 cell wall disruption in other organism(GO:0044278)
0.6 14.9 GO:0051764 actin crosslink formation(GO:0051764)
0.6 15.5 GO:0006623 protein targeting to vacuole(GO:0006623)
0.6 3.0 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.6 3.0 GO:0033216 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.6 6.1 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578) carnitine biosynthetic process(GO:0045329)
0.6 7.3 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.6 4.2 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.6 9.0 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.6 7.8 GO:0006903 vesicle targeting(GO:0006903)
0.6 1.2 GO:0051036 regulation of endosome size(GO:0051036)
0.6 4.8 GO:0008535 respiratory chain complex IV assembly(GO:0008535) mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.6 2.9 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.6 4.1 GO:2000002 negative regulation of cell cycle checkpoint(GO:1901977) negative regulation of DNA damage checkpoint(GO:2000002)
0.6 1.8 GO:0051541 elastin metabolic process(GO:0051541)
0.6 1.7 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.6 1.2 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.6 2.3 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.6 8.6 GO:0040023 establishment of nucleus localization(GO:0040023)
0.6 4.6 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.6 2.3 GO:0065001 negative regulation of histone H3-K36 methylation(GO:0000415) negative regulation of histone H3-K4 methylation(GO:0051572) specification of axis polarity(GO:0065001)
0.6 1.7 GO:0036233 glycine import(GO:0036233)
0.6 5.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.6 6.6 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.5 2.7 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.5 12.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.5 5.9 GO:0070365 hepatocyte differentiation(GO:0070365)
0.5 20.4 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.5 12.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.5 17.0 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.5 2.1 GO:1904293 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) negative regulation of ERAD pathway(GO:1904293)
0.5 4.2 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.5 2.6 GO:0007497 posterior midgut development(GO:0007497) enteric smooth muscle cell differentiation(GO:0035645)
0.5 1.5 GO:2000302 positive regulation of synaptic vesicle priming(GO:0010808) positive regulation of synaptic vesicle transport(GO:1902805) positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.5 8.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.5 12.6 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.5 3.9 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.5 4.8 GO:2000059 negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.5 1.9 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.5 3.3 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.5 9.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.5 4.6 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.5 3.2 GO:0060242 contact inhibition(GO:0060242)
0.5 8.2 GO:0043928 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.5 16.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.5 3.2 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.5 5.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.5 28.5 GO:0045454 cell redox homeostasis(GO:0045454)
0.4 5.8 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.4 2.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.4 2.2 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.4 3.1 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.4 5.7 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.4 8.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.4 3.0 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.4 2.5 GO:0036438 maintenance of lens transparency(GO:0036438)
0.4 1.3 GO:1903069 regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903069) positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.4 4.6 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.4 7.5 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.4 10.2 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.4 3.2 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.4 24.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.4 96.3 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.4 1.6 GO:0048733 sebaceous gland development(GO:0048733)
0.4 1.2 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.4 1.2 GO:2000697 negative regulation by virus of viral protein levels in host cell(GO:0046725) kidney mesenchymal cell proliferation(GO:0072135) metanephric mesenchymal cell proliferation involved in metanephros development(GO:0072136) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.4 2.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.4 15.8 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.4 0.8 GO:0033591 response to L-ascorbic acid(GO:0033591)
0.4 0.4 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.4 0.7 GO:0006598 polyamine catabolic process(GO:0006598) spermidine catabolic process(GO:0046203)
0.4 1.9 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.4 11.9 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.4 3.3 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.4 4.1 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.4 1.8 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
0.4 1.8 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.4 4.3 GO:0006458 'de novo' protein folding(GO:0006458)
0.4 2.2 GO:0043247 telomere maintenance in response to DNA damage(GO:0043247)
0.4 1.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.4 0.7 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.4 4.6 GO:0015884 folic acid transport(GO:0015884)
0.4 1.1 GO:0006726 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.4 2.5 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.4 1.8 GO:0006551 leucine metabolic process(GO:0006551)
0.3 31.0 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.3 2.7 GO:0071888 macrophage apoptotic process(GO:0071888)
0.3 6.0 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.3 5.6 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.3 2.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.3 2.6 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.3 12.1 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.3 8.3 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.3 2.5 GO:0046836 glycolipid transport(GO:0046836)
0.3 1.6 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.3 16.0 GO:0016925 protein sumoylation(GO:0016925)
0.3 1.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.3 3.4 GO:0034063 stress granule assembly(GO:0034063)
0.3 1.5 GO:0097052 L-kynurenine metabolic process(GO:0097052)
0.3 5.2 GO:0006829 zinc II ion transport(GO:0006829)
0.3 7.5 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.3 3.3 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.3 27.1 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.3 11.3 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.3 1.9 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.3 13.2 GO:0032508 DNA duplex unwinding(GO:0032508)
0.3 3.5 GO:0001553 luteinization(GO:0001553)
0.3 2.9 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.3 2.9 GO:1902186 regulation of viral release from host cell(GO:1902186)
0.3 2.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 2.0 GO:0072599 establishment of protein localization to endoplasmic reticulum(GO:0072599)
0.3 9.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.3 9.3 GO:0030224 monocyte differentiation(GO:0030224)
0.2 3.2 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.2 1.5 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.2 2.5 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.2 2.0 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.2 7.8 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.2 18.5 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.2 5.6 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.2 1.2 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.2 0.7 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.2 2.5 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.2 3.8 GO:0042359 vitamin D metabolic process(GO:0042359)
0.2 1.6 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.2 0.9 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.2 1.6 GO:0060536 cartilage morphogenesis(GO:0060536)
0.2 1.3 GO:0042976 activation of Janus kinase activity(GO:0042976)
0.2 11.7 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.2 2.1 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 0.4 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.2 1.5 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 0.8 GO:0003340 regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003339) negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.2 6.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.2 1.6 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.2 3.1 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.2 1.8 GO:0060546 negative regulation of necroptotic process(GO:0060546)
0.2 9.8 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.2 0.4 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.2 3.2 GO:1901186 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742) positive regulation of ERBB signaling pathway(GO:1901186)
0.2 1.3 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.2 0.6 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
0.2 3.8 GO:0000042 protein targeting to Golgi(GO:0000042)
0.2 5.6 GO:0005980 glycogen catabolic process(GO:0005980)
0.2 0.7 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.2 4.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 4.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 1.8 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.2 0.8 GO:0055064 chloride ion homeostasis(GO:0055064)
0.2 0.5 GO:1901529 positive regulation of anion channel activity(GO:1901529) positive regulation of anion transmembrane transport(GO:1903961)
0.2 0.8 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.2 3.9 GO:0030517 negative regulation of axon extension(GO:0030517)
0.2 7.8 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.2 0.5 GO:0036071 N-glycan fucosylation(GO:0036071)
0.2 1.8 GO:0090382 phagosome maturation(GO:0090382)
0.2 1.4 GO:0097264 self proteolysis(GO:0097264)
0.2 1.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.2 3.7 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.2 3.6 GO:1901998 toxin transport(GO:1901998)
0.2 0.2 GO:0032071 regulation of deoxyribonuclease activity(GO:0032070) regulation of endodeoxyribonuclease activity(GO:0032071)
0.1 17.2 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.1 4.2 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.9 GO:0097104 postsynaptic membrane assembly(GO:0097104)
0.1 1.0 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 0.7 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.1 0.7 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 2.6 GO:0007635 chemosensory behavior(GO:0007635)
0.1 3.7 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.1 0.5 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 0.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 7.0 GO:0051225 spindle assembly(GO:0051225)
0.1 0.6 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.6 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.1 0.6 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.1 0.3 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.1 0.1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.2 GO:0071389 cellular response to mineralocorticoid stimulus(GO:0071389)
0.1 0.6 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 0.9 GO:0016180 snRNA processing(GO:0016180)
0.1 2.1 GO:0003382 epithelial cell morphogenesis(GO:0003382)
0.1 11.2 GO:0007018 microtubule-based movement(GO:0007018)
0.1 1.4 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.1 2.8 GO:0043171 peptide catabolic process(GO:0043171)
0.1 1.2 GO:0044705 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.1 1.6 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.7 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 1.7 GO:0006826 iron ion transport(GO:0006826)
0.1 0.8 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 1.1 GO:0018345 protein palmitoylation(GO:0018345)
0.1 2.0 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.1 0.2 GO:0035425 autocrine signaling(GO:0035425)
0.1 1.1 GO:0046835 carbohydrate phosphorylation(GO:0046835)
0.0 2.8 GO:0045333 cellular respiration(GO:0045333)
0.0 3.3 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 2.7 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.3 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.3 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.0 0.8 GO:0060416 response to growth hormone(GO:0060416)
0.0 0.5 GO:0006298 mismatch repair(GO:0006298)
0.0 0.6 GO:0032232 negative regulation of actin filament bundle assembly(GO:0032232)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.3 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.0 0.3 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.3 GO:0010226 response to lithium ion(GO:0010226)
0.0 1.3 GO:0045727 positive regulation of translation(GO:0045727)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.6 GO:0018208 protein peptidyl-prolyl isomerization(GO:0000413) peptidyl-proline modification(GO:0018208)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.5 GO:0046037 GMP metabolic process(GO:0046037)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
26.9 80.8 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
19.6 58.9 GO:0032419 extrinsic component of lysosome membrane(GO:0032419)
12.2 36.6 GO:0031262 Ndc80 complex(GO:0031262)
10.3 41.1 GO:1990423 RZZ complex(GO:1990423)
10.2 30.7 GO:0034515 proteasome storage granule(GO:0034515)
8.7 43.3 GO:0043564 Ku70:Ku80 complex(GO:0043564)
8.6 102.8 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
8.0 23.9 GO:0071148 TEAD-1-YAP complex(GO:0071148)
7.7 46.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
7.3 21.9 GO:0031933 telomeric heterochromatin(GO:0031933)
7.1 35.4 GO:0097149 centralspindlin complex(GO:0097149)
7.0 62.7 GO:0032133 chromosome passenger complex(GO:0032133)
6.7 26.8 GO:0031510 SUMO activating enzyme complex(GO:0031510)
6.6 26.4 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
6.5 32.5 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
6.3 18.8 GO:0071001 U4/U6 snRNP(GO:0071001)
6.2 49.9 GO:0070761 pre-snoRNP complex(GO:0070761)
6.2 68.1 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
6.0 29.8 GO:0032044 DSIF complex(GO:0032044)
5.7 28.7 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
5.7 22.9 GO:0000811 GINS complex(GO:0000811)
5.7 56.7 GO:0005785 signal recognition particle receptor complex(GO:0005785)
5.6 16.8 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
5.6 55.5 GO:0031595 nuclear proteasome complex(GO:0031595)
5.5 55.1 GO:0070852 cell body fiber(GO:0070852)
5.2 36.7 GO:0044326 dendritic spine neck(GO:0044326)
5.2 36.2 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
5.1 30.4 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
5.0 30.0 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
5.0 14.9 GO:0033565 ESCRT-0 complex(GO:0033565)
5.0 64.4 GO:0002199 zona pellucida receptor complex(GO:0002199)
4.8 24.0 GO:0001940 male pronucleus(GO:0001940)
4.8 19.0 GO:0005715 late recombination nodule(GO:0005715)
4.6 13.8 GO:0035370 UBC13-UEV1A complex(GO:0035370)
4.6 41.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
4.6 41.0 GO:0072546 ER membrane protein complex(GO:0072546)
4.5 26.8 GO:0031597 cytosolic proteasome complex(GO:0031597)
4.5 13.4 GO:0044611 nuclear pore inner ring(GO:0044611)
4.4 13.2 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
4.4 26.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
4.4 122.1 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
4.3 13.0 GO:0033167 ARC complex(GO:0033167)
4.0 12.1 GO:0097414 glial cytoplasmic inclusion(GO:0097409) classical Lewy body(GO:0097414) Lewy neurite(GO:0097462) Lewy body corona(GO:1990038)
3.9 46.5 GO:0030126 COPI vesicle coat(GO:0030126)
3.8 30.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
3.7 11.2 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
3.7 18.7 GO:0000408 EKC/KEOPS complex(GO:0000408)
3.7 63.3 GO:0031080 nuclear pore outer ring(GO:0031080)
3.7 37.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
3.6 46.6 GO:0033093 Weibel-Palade body(GO:0033093)
3.5 14.2 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
3.5 24.5 GO:0090661 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
3.5 13.9 GO:0001405 presequence translocase-associated import motor(GO:0001405)
3.5 48.4 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
3.4 10.3 GO:0005588 collagen type V trimer(GO:0005588)
3.4 27.4 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
3.3 29.8 GO:0070652 HAUS complex(GO:0070652)
3.2 15.8 GO:0001651 dense fibrillar component(GO:0001651)
3.2 19.0 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
3.2 9.5 GO:0002079 inner acrosomal membrane(GO:0002079)
3.0 15.1 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
3.0 54.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
2.8 8.5 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
2.8 25.3 GO:0042382 paraspeckles(GO:0042382)
2.8 11.1 GO:0005960 glycine cleavage complex(GO:0005960)
2.8 41.3 GO:0034709 methylosome(GO:0034709)
2.6 7.9 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
2.6 7.9 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
2.6 33.9 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
2.6 2.6 GO:0071920 cleavage body(GO:0071920)
2.5 30.4 GO:0005688 U6 snRNP(GO:0005688)
2.4 14.6 GO:0061617 MICOS complex(GO:0061617)
2.4 9.5 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
2.3 14.0 GO:0009368 endopeptidase Clp complex(GO:0009368)
2.3 66.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
2.3 36.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
2.2 6.6 GO:0045323 interleukin-1 receptor complex(GO:0045323)
2.2 10.9 GO:0030896 checkpoint clamp complex(GO:0030896)
2.2 17.4 GO:0000796 condensin complex(GO:0000796)
2.2 28.3 GO:0005838 proteasome regulatory particle(GO:0005838)
2.2 32.6 GO:0045277 respiratory chain complex IV(GO:0045277)
2.1 17.0 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
2.1 25.1 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
2.1 122.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
2.1 16.6 GO:0005827 polar microtubule(GO:0005827)
2.1 4.1 GO:0070939 Dsl1p complex(GO:0070939)
2.1 12.3 GO:0070545 PeBoW complex(GO:0070545)
2.0 42.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
2.0 8.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
2.0 8.0 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
2.0 15.9 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
1.9 13.6 GO:0097550 transcriptional preinitiation complex(GO:0097550)
1.9 21.3 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
1.9 5.8 GO:0034657 GID complex(GO:0034657)
1.9 9.5 GO:0005685 U1 snRNP(GO:0005685)
1.9 9.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
1.8 9.1 GO:0032301 MutSalpha complex(GO:0032301)
1.8 10.8 GO:0005839 proteasome core complex(GO:0005839)
1.8 5.3 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
1.8 15.9 GO:0044754 autolysosome(GO:0044754)
1.8 1.8 GO:0000346 transcription export complex(GO:0000346)
1.7 5.2 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
1.7 27.7 GO:0097470 ribbon synapse(GO:0097470)
1.7 5.2 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
1.7 18.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
1.7 13.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
1.7 30.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
1.7 6.7 GO:0071986 Ragulator complex(GO:0071986)
1.7 5.0 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
1.7 18.4 GO:0000974 Prp19 complex(GO:0000974)
1.7 3.3 GO:0005899 insulin receptor complex(GO:0005899)
1.7 11.6 GO:0016272 prefoldin complex(GO:0016272)
1.6 123.6 GO:0015935 small ribosomal subunit(GO:0015935)
1.6 17.9 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
1.6 6.3 GO:0005846 nuclear cap binding complex(GO:0005846)
1.6 6.3 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
1.5 21.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
1.5 19.8 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.5 58.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
1.5 17.6 GO:0005869 dynactin complex(GO:0005869)
1.5 17.5 GO:0071203 WASH complex(GO:0071203)
1.5 68.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
1.4 37.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
1.4 15.8 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
1.4 8.5 GO:1990357 terminal web(GO:1990357)
1.4 23.9 GO:0035748 myelin sheath abaxonal region(GO:0035748)
1.4 9.8 GO:0044530 supraspliceosomal complex(GO:0044530)
1.4 5.4 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
1.3 62.5 GO:0008180 COP9 signalosome(GO:0008180)
1.3 42.5 GO:0005684 U2-type spliceosomal complex(GO:0005684)
1.3 35.8 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
1.3 3.9 GO:0034455 t-UTP complex(GO:0034455)
1.3 2.6 GO:0002139 stereocilia coupling link(GO:0002139)
1.3 8.9 GO:0034719 SMN-Sm protein complex(GO:0034719)
1.3 8.9 GO:0090543 Flemming body(GO:0090543)
1.3 20.2 GO:0033276 transcription factor TFTC complex(GO:0033276)
1.3 44.2 GO:0031258 lamellipodium membrane(GO:0031258)
1.3 208.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
1.2 30.0 GO:0005640 nuclear outer membrane(GO:0005640)
1.2 9.9 GO:0070187 telosome(GO:0070187)
1.2 26.1 GO:0032433 filopodium tip(GO:0032433)
1.2 29.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
1.2 3.6 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
1.2 38.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
1.2 9.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
1.2 26.5 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
1.2 6.9 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
1.1 9.1 GO:0031931 TORC1 complex(GO:0031931)
1.1 4.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
1.1 60.9 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
1.1 26.6 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
1.1 2.2 GO:0055087 Ski complex(GO:0055087)
1.1 5.5 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
1.1 4.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
1.1 10.6 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
1.0 54.1 GO:1904115 axon cytoplasm(GO:1904115)
1.0 3.1 GO:1902636 kinociliary basal body(GO:1902636)
1.0 65.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
1.0 3.0 GO:0005663 DNA replication factor C complex(GO:0005663)
1.0 8.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
1.0 10.5 GO:0071141 SMAD protein complex(GO:0071141)
0.9 10.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.9 19.8 GO:0030056 hemidesmosome(GO:0030056)
0.9 3.7 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.9 9.2 GO:0070552 BRISC complex(GO:0070552)
0.9 4.6 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.9 2.7 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
0.9 8.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.8 4.1 GO:0070847 core mediator complex(GO:0070847)
0.8 11.5 GO:0005641 nuclear envelope lumen(GO:0005641)
0.8 2.4 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.8 3.2 GO:0044307 dendritic branch(GO:0044307)
0.8 6.3 GO:0061689 tricellular tight junction(GO:0061689)
0.8 2.4 GO:0031905 early endosome lumen(GO:0031905)
0.8 13.1 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.8 57.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.8 3.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.8 8.3 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.7 20.7 GO:0031143 pseudopodium(GO:0031143)
0.7 5.1 GO:0030891 VCB complex(GO:0030891)
0.7 5.7 GO:0034464 BBSome(GO:0034464)
0.7 8.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.7 4.3 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.7 15.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.7 7.7 GO:1990023 mitotic spindle midzone(GO:1990023)
0.7 13.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.7 82.2 GO:0031985 Golgi cisterna(GO:0031985)
0.7 7.6 GO:0031209 SCAR complex(GO:0031209)
0.7 4.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.7 18.4 GO:0005680 anaphase-promoting complex(GO:0005680)
0.7 7.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.7 33.1 GO:0005771 multivesicular body(GO:0005771)
0.7 2.0 GO:0071817 MMXD complex(GO:0071817)
0.7 41.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.7 8.5 GO:0070469 respiratory chain(GO:0070469)
0.6 67.3 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.6 4.5 GO:0005610 laminin-5 complex(GO:0005610)
0.6 20.9 GO:0099738 cell cortex region(GO:0099738)
0.6 31.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.6 2.9 GO:0036021 endolysosome lumen(GO:0036021)
0.6 20.7 GO:0016592 mediator complex(GO:0016592)
0.6 133.9 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.6 55.7 GO:0015934 large ribosomal subunit(GO:0015934)
0.5 6.0 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.5 11.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.5 8.0 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.5 8.9 GO:0000930 gamma-tubulin complex(GO:0000930)
0.5 5.7 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.5 14.6 GO:0005876 spindle microtubule(GO:0005876)
0.5 10.9 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.5 8.1 GO:0000776 kinetochore(GO:0000776)
0.5 2.5 GO:0045120 pronucleus(GO:0045120)
0.5 3.3 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.5 3.8 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.5 24.1 GO:0002102 podosome(GO:0002102)
0.5 12.8 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.5 12.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.4 4.0 GO:0000815 ESCRT III complex(GO:0000815)
0.4 2.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.4 122.5 GO:0031965 nuclear membrane(GO:0031965)
0.4 18.3 GO:0090544 BAF-type complex(GO:0090544)
0.4 62.2 GO:0000793 condensed chromosome(GO:0000793)
0.4 2.5 GO:0035861 site of double-strand break(GO:0035861)
0.4 1.2 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.4 1.6 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.4 1.6 GO:0035841 new growing cell tip(GO:0035841)
0.4 1.2 GO:0070557 PCNA-p21 complex(GO:0070557)
0.4 6.1 GO:0031941 filamentous actin(GO:0031941)
0.4 16.9 GO:0045171 intercellular bridge(GO:0045171)
0.4 11.3 GO:0005795 Golgi stack(GO:0005795)
0.4 24.9 GO:0005811 lipid particle(GO:0005811)
0.4 1.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.4 5.3 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.3 16.1 GO:0072686 mitotic spindle(GO:0072686)
0.3 49.1 GO:0005635 nuclear envelope(GO:0005635)
0.3 3.1 GO:0005675 holo TFIIH complex(GO:0005675)
0.3 1.3 GO:1990037 Lewy body core(GO:1990037)
0.3 3.6 GO:0005652 nuclear lamina(GO:0005652)
0.3 1.9 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.3 3.6 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.3 31.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.3 23.8 GO:0070821 tertiary granule membrane(GO:0070821)
0.3 8.9 GO:0045095 keratin filament(GO:0045095)
0.2 1.2 GO:0033503 HULC complex(GO:0033503)
0.2 3.1 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2 34.2 GO:0005819 spindle(GO:0005819)
0.2 3.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 2.0 GO:0005787 signal peptidase complex(GO:0005787)
0.2 4.0 GO:1902555 endoribonuclease complex(GO:1902555)
0.2 20.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.2 50.3 GO:0030529 intracellular ribonucleoprotein complex(GO:0030529)
0.2 2.7 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.2 1.7 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.2 2.6 GO:0031528 microvillus membrane(GO:0031528)
0.2 1.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 149.3 GO:0005730 nucleolus(GO:0005730)
0.2 4.0 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.2 11.9 GO:0032432 actin filament bundle(GO:0032432)
0.2 16.1 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.2 43.3 GO:0005759 mitochondrial matrix(GO:0005759)
0.2 13.2 GO:0016605 PML body(GO:0016605)
0.2 0.5 GO:0032389 MutLalpha complex(GO:0032389)
0.1 19.4 GO:0043197 dendritic spine(GO:0043197)
0.1 0.4 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.1 2.2 GO:0035102 PRC1 complex(GO:0035102)
0.1 3.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.5 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.1 5.3 GO:0005814 centriole(GO:0005814)
0.1 0.9 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.9 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.2 GO:0032280 symmetric synapse(GO:0032280)
0.1 10.3 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 12.8 GO:0000785 chromatin(GO:0000785)
0.0 0.9 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 2.0 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.2 GO:0000938 GARP complex(GO:0000938)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
12.4 37.1 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
11.0 54.9 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
10.6 74.5 GO:0004849 uridine kinase activity(GO:0004849)
10.4 41.4 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
10.2 30.5 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
9.8 29.3 GO:0004638 phosphoribosylaminoimidazole carboxylase activity(GO:0004638) phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
9.3 37.1 GO:0070404 NADH binding(GO:0070404)
8.9 53.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
8.2 48.9 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
8.1 48.4 GO:0005047 signal recognition particle binding(GO:0005047)
8.0 40.1 GO:0017161 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
8.0 103.8 GO:1990825 sequence-specific mRNA binding(GO:1990825)
7.8 23.4 GO:0003896 DNA primase activity(GO:0003896)
7.5 30.0 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
7.3 21.9 GO:0015616 DNA translocase activity(GO:0015616)
7.2 36.2 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
7.2 28.7 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
7.0 49.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
6.9 20.7 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
6.8 20.4 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
6.7 20.0 GO:0044594 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
6.6 19.9 GO:0070538 oleic acid binding(GO:0070538)
6.3 25.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
6.3 31.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
6.1 18.2 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
6.0 53.7 GO:0035174 histone serine kinase activity(GO:0035174)
5.8 29.2 GO:1903135 cupric ion binding(GO:1903135)
5.8 17.5 GO:0004998 transferrin receptor activity(GO:0004998)
5.6 16.8 GO:0048030 disaccharide binding(GO:0048030)
5.4 32.6 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
5.3 16.0 GO:0000035 acyl binding(GO:0000035)
5.3 16.0 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
5.3 15.9 GO:0031208 POZ domain binding(GO:0031208)
5.3 148.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
5.3 15.8 GO:0034512 box C/D snoRNA binding(GO:0034512)
5.1 30.7 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
5.1 30.4 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
5.0 15.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
4.9 19.5 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
4.8 43.3 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
4.8 19.2 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
4.8 19.2 GO:0003883 CTP synthase activity(GO:0003883)
4.8 9.5 GO:0035614 snRNA stem-loop binding(GO:0035614)
4.7 33.2 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
4.5 13.4 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
4.4 39.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
4.2 41.8 GO:0042731 PH domain binding(GO:0042731)
4.2 49.9 GO:0070053 thrombospondin receptor activity(GO:0070053)
4.1 53.1 GO:0008641 small protein activating enzyme activity(GO:0008641)
3.9 27.5 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
3.9 23.5 GO:0030621 U4 snRNA binding(GO:0030621)
3.8 15.1 GO:0033677 DNA/RNA helicase activity(GO:0033677)
3.8 11.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
3.8 49.0 GO:0008494 translation activator activity(GO:0008494)
3.7 11.1 GO:0004047 aminomethyltransferase activity(GO:0004047)
3.6 10.9 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
3.6 14.3 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
3.5 10.6 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
3.5 49.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
3.5 24.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
3.4 6.8 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
3.4 33.9 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
3.4 13.5 GO:0042809 vitamin D receptor binding(GO:0042809)
3.4 64.1 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
3.3 36.4 GO:0051920 peroxiredoxin activity(GO:0051920)
3.2 19.3 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
3.1 83.3 GO:0070628 proteasome binding(GO:0070628)
3.1 12.3 GO:0004504 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
3.1 15.3 GO:0042296 ISG15 transferase activity(GO:0042296)
3.0 48.6 GO:1901612 cardiolipin binding(GO:1901612)
3.0 123.4 GO:0070717 poly-purine tract binding(GO:0070717)
3.0 54.0 GO:0019871 sodium channel inhibitor activity(GO:0019871)
2.9 8.8 GO:0047787 geranylgeranyl reductase activity(GO:0045550) delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
2.9 17.5 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
2.8 16.8 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
2.8 19.3 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
2.7 10.9 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
2.7 106.7 GO:0000049 tRNA binding(GO:0000049)
2.6 20.9 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
2.6 12.8 GO:0045504 dynein heavy chain binding(GO:0045504)
2.6 12.8 GO:0004427 inorganic diphosphatase activity(GO:0004427)
2.6 7.7 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
2.4 7.3 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
2.4 7.3 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
2.4 21.5 GO:0008266 poly(U) RNA binding(GO:0008266)
2.4 21.3 GO:0019784 NEDD8-specific protease activity(GO:0019784)
2.4 113.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
2.4 16.5 GO:0005347 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
2.3 32.8 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
2.3 6.9 GO:0098519 polynucleotide 5'-phosphatase activity(GO:0004651) nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
2.3 97.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
2.2 6.7 GO:0031626 beta-endorphin binding(GO:0031626)
2.2 26.6 GO:0032137 guanine/thymine mispair binding(GO:0032137)
2.2 61.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
2.2 26.3 GO:0004526 ribonuclease P activity(GO:0004526)
2.2 39.4 GO:0035497 cAMP response element binding(GO:0035497)
2.2 8.7 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
2.2 15.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
2.2 8.6 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
2.1 34.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
2.1 10.7 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
2.1 81.0 GO:0005540 hyaluronic acid binding(GO:0005540)
2.1 8.5 GO:0043515 kinetochore binding(GO:0043515)
2.1 17.0 GO:0004485 methylcrotonoyl-CoA carboxylase activity(GO:0004485)
2.1 95.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
2.1 75.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
2.1 23.0 GO:0015266 protein channel activity(GO:0015266)
2.1 6.3 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
2.0 28.6 GO:0031386 protein tag(GO:0031386)
2.0 8.2 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
2.0 20.3 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
2.0 8.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
2.0 4.1 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
2.0 6.1 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
2.0 16.0 GO:0015288 porin activity(GO:0015288)
2.0 35.8 GO:0001055 RNA polymerase II activity(GO:0001055)
2.0 19.8 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
2.0 7.8 GO:0016524 latrotoxin receptor activity(GO:0016524)
1.9 7.7 GO:0070990 snRNP binding(GO:0070990) U1 snRNP binding(GO:1990446)
1.9 5.8 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
1.9 24.9 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
1.9 13.4 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
1.9 22.6 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
1.9 7.5 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
1.8 9.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
1.8 138.6 GO:0019003 GDP binding(GO:0019003)
1.8 5.5 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
1.8 9.0 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
1.8 1.8 GO:0016419 [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420)
1.8 5.4 GO:0004531 deoxyribonuclease II activity(GO:0004531) endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
1.7 14.0 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
1.7 12.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
1.7 5.2 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
1.7 36.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
1.7 6.8 GO:0035800 deubiquitinase activator activity(GO:0035800)
1.7 17.0 GO:0051371 muscle alpha-actinin binding(GO:0051371)
1.7 114.7 GO:0003743 translation initiation factor activity(GO:0003743)
1.7 23.6 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
1.7 5.0 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
1.7 36.5 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
1.6 17.8 GO:0033038 bitter taste receptor activity(GO:0033038)
1.6 11.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
1.6 43.2 GO:0017025 TBP-class protein binding(GO:0017025)
1.5 55.7 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
1.5 9.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
1.5 10.5 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.5 38.9 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
1.5 13.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
1.5 10.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
1.5 4.4 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
1.4 5.7 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
1.4 7.1 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
1.4 18.3 GO:0046790 virion binding(GO:0046790)
1.4 4.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
1.4 8.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
1.4 23.5 GO:0017049 GTP-Rho binding(GO:0017049)
1.4 12.4 GO:0089720 caspase binding(GO:0089720)
1.4 16.5 GO:0038132 neuregulin binding(GO:0038132)
1.4 38.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
1.3 10.7 GO:0050733 RS domain binding(GO:0050733)
1.3 6.7 GO:0004311 farnesyltranstransferase activity(GO:0004311)
1.3 5.3 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
1.3 29.3 GO:0008242 omega peptidase activity(GO:0008242)
1.3 29.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
1.3 6.6 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
1.3 7.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
1.3 6.5 GO:0016936 galactoside binding(GO:0016936)
1.3 5.1 GO:0002060 purine nucleobase binding(GO:0002060) glycogen phosphorylase activity(GO:0008184)
1.3 15.4 GO:0043495 protein anchor(GO:0043495)
1.3 2.6 GO:0010521 telomerase inhibitor activity(GO:0010521)
1.3 3.8 GO:1902271 D3 vitamins binding(GO:1902271)
1.3 2.5 GO:0017089 glycolipid transporter activity(GO:0017089)
1.3 5.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
1.2 17.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.2 4.9 GO:0034186 apolipoprotein A-I binding(GO:0034186)
1.2 61.2 GO:0004385 guanylate kinase activity(GO:0004385)
1.2 31.4 GO:0070840 dynein complex binding(GO:0070840)
1.2 39.5 GO:0001671 ATPase activator activity(GO:0001671)
1.2 9.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
1.2 42.5 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
1.2 59.8 GO:0048487 beta-tubulin binding(GO:0048487)
1.2 5.8 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
1.2 8.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
1.1 5.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.1 3.4 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
1.1 19.1 GO:0031369 translation initiation factor binding(GO:0031369)
1.1 44.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.1 3.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.1 5.5 GO:0019776 Atg8 ligase activity(GO:0019776)
1.1 29.3 GO:0000993 RNA polymerase II core binding(GO:0000993)
1.1 3.3 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
1.1 5.3 GO:0016882 cyclo-ligase activity(GO:0016882)
1.1 17.0 GO:0017128 phospholipid scramblase activity(GO:0017128)
1.1 10.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
1.1 7.4 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
1.0 11.4 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
1.0 28.9 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
1.0 11.3 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
1.0 3.0 GO:0055100 adiponectin binding(GO:0055100)
1.0 5.0 GO:0019798 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
1.0 10.1 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
1.0 7.8 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
1.0 5.8 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.0 25.3 GO:0001848 complement binding(GO:0001848)
1.0 26.3 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.0 4.8 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.9 12.3 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.9 7.3 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.9 10.0 GO:0050700 CARD domain binding(GO:0050700)
0.9 5.5 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.9 29.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.9 2.6 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
0.9 2.6 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.9 3.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.9 2.6 GO:0004556 alpha-amylase activity(GO:0004556)
0.9 12.0 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.9 20.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.9 7.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.9 15.4 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.8 65.1 GO:0097110 scaffold protein binding(GO:0097110)
0.8 9.8 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
0.8 2.4 GO:0042020 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.8 14.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.8 21.5 GO:0070064 proline-rich region binding(GO:0070064)
0.8 3.2 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.8 17.4 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442) ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.8 8.6 GO:0032051 clathrin light chain binding(GO:0032051)
0.8 29.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.8 13.1 GO:0008327 methyl-CpG binding(GO:0008327)
0.8 5.4 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.8 23.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.8 10.7 GO:0050786 RAGE receptor binding(GO:0050786)
0.8 3.8 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.8 3.0 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.8 14.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.7 6.7 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.7 20.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.7 58.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.7 15.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.7 2.2 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.7 2.1 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.7 8.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.7 7.8 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.7 2.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.7 4.9 GO:0016421 CoA carboxylase activity(GO:0016421)
0.7 5.6 GO:0015232 heme transporter activity(GO:0015232)
0.7 1.4 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.7 5.5 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.7 5.5 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.7 34.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.7 4.6 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.7 8.6 GO:0008432 JUN kinase binding(GO:0008432)
0.7 29.7 GO:0019894 kinesin binding(GO:0019894)
0.7 130.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.6 13.6 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.6 12.8 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.6 10.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.6 24.0 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.6 6.8 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.6 2.5 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.6 16.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.6 37.5 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.6 6.1 GO:0034594 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.6 6.0 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.6 12.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.6 6.0 GO:0051434 BH3 domain binding(GO:0051434)
0.6 1.7 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.6 4.0 GO:0017091 AU-rich element binding(GO:0017091)
0.5 2.2 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.5 13.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.5 4.3 GO:0043422 protein kinase B binding(GO:0043422)
0.5 6.5 GO:0045505 dynein light chain binding(GO:0045503) dynein intermediate chain binding(GO:0045505)
0.5 2.7 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.5 19.8 GO:0008536 Ran GTPase binding(GO:0008536)
0.5 11.0 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.5 1.6 GO:0052854 (S)-2-hydroxy-acid oxidase activity(GO:0003973) oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.5 7.3 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.5 8.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.5 18.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.5 1.5 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.5 28.3 GO:0035064 methylated histone binding(GO:0035064)
0.5 2.5 GO:0004771 sterol esterase activity(GO:0004771)
0.5 10.9 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.5 4.2 GO:0019158 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.5 8.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.5 83.5 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.5 11.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.4 9.4 GO:0030515 snoRNA binding(GO:0030515)
0.4 9.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.4 5.2 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.4 1.3 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.4 12.7 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.4 4.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.4 7.0 GO:0070410 co-SMAD binding(GO:0070410)
0.4 6.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.4 3.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.4 1.9 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.4 3.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.4 11.4 GO:0003774 motor activity(GO:0003774)
0.4 35.3 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.4 7.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.4 2.6 GO:0004962 endothelin receptor activity(GO:0004962)
0.4 2.9 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.4 2.5 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.4 5.4 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.4 2.2 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.4 12.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.4 5.0 GO:0045502 dynein binding(GO:0045502)
0.4 1.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.4 1.8 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.3 38.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3 15.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.3 2.8 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 4.4 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.3 1.0 GO:0019826 oxygen sensor activity(GO:0019826)
0.3 3.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.3 1.3 GO:0004925 prolactin receptor activity(GO:0004925)
0.3 21.6 GO:0030276 clathrin binding(GO:0030276)
0.3 5.8 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.3 1.3 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.3 3.5 GO:0043295 glutathione binding(GO:0043295)
0.3 4.0 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.3 1.6 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.3 1.9 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 1.2 GO:0004743 pyruvate kinase activity(GO:0004743)
0.3 103.3 GO:0045296 cadherin binding(GO:0045296)
0.3 12.0 GO:0050699 WW domain binding(GO:0050699)
0.3 1.7 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.3 2.3 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733) galactose 3-O-sulfotransferase activity(GO:0050694)
0.3 4.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.3 7.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 4.2 GO:0050811 GABA receptor binding(GO:0050811)
0.3 8.6 GO:0032947 protein complex scaffold(GO:0032947)
0.3 2.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.3 2.5 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.3 1.6 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.3 0.3 GO:0031849 olfactory receptor binding(GO:0031849)
0.3 2.8 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.3 6.4 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.2 9.5 GO:0019905 syntaxin binding(GO:0019905)
0.2 0.7 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.2 1.2 GO:0016778 diphosphotransferase activity(GO:0016778)
0.2 0.9 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.2 2.3 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.2 3.9 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.2 2.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 4.7 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.2 3.8 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.2 0.7 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.2 6.5 GO:0042169 SH2 domain binding(GO:0042169)
0.2 2.4 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 3.0 GO:0004383 guanylate cyclase activity(GO:0004383)
0.2 1.8 GO:0000149 SNARE binding(GO:0000149)
0.2 2.9 GO:0008517 folic acid transporter activity(GO:0008517)
0.2 12.6 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.2 4.6 GO:0030331 estrogen receptor binding(GO:0030331)
0.2 0.7 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.2 9.5 GO:0046332 SMAD binding(GO:0046332)
0.2 2.2 GO:0008135 translation factor activity, RNA binding(GO:0008135)
0.2 30.4 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.2 1.5 GO:1990459 transferrin receptor binding(GO:1990459)
0.2 0.5 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.2 26.5 GO:0051015 actin filament binding(GO:0051015)
0.1 0.4 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 14.8 GO:0042393 histone binding(GO:0042393)
0.1 1.9 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.5 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 5.2 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.1 6.9 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 0.6 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 2.0 GO:0005537 mannose binding(GO:0005537)
0.1 4.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 0.8 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 1.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 7.3 GO:0030165 PDZ domain binding(GO:0030165)
0.1 3.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.1 1.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 19.3 GO:0008017 microtubule binding(GO:0008017)
0.1 2.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 47.3 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.1 2.3 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.5 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 6.7 GO:0008565 protein transporter activity(GO:0008565)
0.1 0.4 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.1 0.4 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1 0.2 GO:1990763 arrestin family protein binding(GO:1990763)
0.1 0.1 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.1 1.0 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 1.0 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.4 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.3 GO:0035240 dopamine binding(GO:0035240)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 3.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 9.4 GO:0003712 transcription cofactor activity(GO:0003712)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 1.6 GO:0005178 integrin binding(GO:0005178)
0.0 0.5 GO:0031593 polyubiquitin binding(GO:0031593)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 3.0 PID FAS PATHWAY FAS (CD95) signaling pathway
2.3 177.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
2.3 70.8 PID FANCONI PATHWAY Fanconi anemia pathway
1.9 95.0 PID BARD1 PATHWAY BARD1 signaling events
1.7 66.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
1.6 9.5 PID IL6 7 PATHWAY IL6-mediated signaling events
1.5 49.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
1.4 91.3 PID PLK1 PATHWAY PLK1 signaling events
1.4 56.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
1.4 36.9 PID S1P S1P1 PATHWAY S1P1 pathway
1.3 87.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
1.3 50.8 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
1.1 4.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
1.0 46.9 PID HIF2PATHWAY HIF-2-alpha transcription factor network
1.0 39.1 PID MYC PATHWAY C-MYC pathway
1.0 9.2 PID NECTIN PATHWAY Nectin adhesion pathway
1.0 91.1 PID E2F PATHWAY E2F transcription factor network
0.9 86.3 PID CDC42 PATHWAY CDC42 signaling events
0.9 51.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.8 30.9 PID IL3 PATHWAY IL3-mediated signaling events
0.8 25.0 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.8 49.8 PID RHOA PATHWAY RhoA signaling pathway
0.8 34.6 PID AURORA B PATHWAY Aurora B signaling
0.8 9.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.8 21.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.7 58.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.7 118.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.7 22.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.7 22.7 PID IL2 1PATHWAY IL2-mediated signaling events
0.7 8.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.6 5.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.6 9.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.6 10.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.6 10.8 PID AURORA A PATHWAY Aurora A signaling
0.6 55.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.6 9.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.6 13.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.6 16.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.6 16.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.6 32.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.6 8.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.6 10.5 PID ALK2 PATHWAY ALK2 signaling events
0.5 13.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.5 37.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.5 22.0 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.5 23.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.5 17.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.4 6.9 PID ATM PATHWAY ATM pathway
0.4 2.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.4 13.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.4 13.0 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.4 4.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.3 21.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.3 7.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.3 5.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.3 6.6 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.3 4.0 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.2 5.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.2 2.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 6.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 2.9 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 3.9 SIG CHEMOTAXIS Genes related to chemotaxis
0.2 1.8 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 5.6 PID ENDOTHELIN PATHWAY Endothelins
0.1 8.1 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.1 2.1 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 4.0 PID ARF6 PATHWAY Arf6 signaling events
0.1 4.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 3.1 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.1 2.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 1.3 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 2.5 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
9.2 83.0 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
6.6 26.4 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
4.6 316.0 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
4.4 70.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
4.4 21.9 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
4.2 46.5 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
4.1 61.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
4.0 124.5 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
3.8 91.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
3.6 36.1 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
3.6 43.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
3.4 37.1 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
3.4 131.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
3.1 94.3 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
2.9 57.9 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
2.9 74.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
2.8 67.4 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
2.7 231.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
2.7 149.0 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
2.7 42.5 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
2.5 71.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
2.5 37.6 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
2.5 49.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
2.4 79.5 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
2.4 43.0 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
2.2 31.0 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
2.2 70.1 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
2.2 32.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
2.1 14.4 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
2.0 60.9 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
2.0 36.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
2.0 15.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
1.9 21.4 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
1.9 36.9 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
1.9 17.0 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
1.8 35.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
1.7 41.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
1.7 38.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
1.7 63.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
1.6 35.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
1.6 12.8 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
1.6 35.2 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
1.6 25.1 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
1.5 29.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
1.5 48.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
1.5 21.8 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
1.4 6.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
1.4 40.6 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
1.3 97.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
1.3 9.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
1.3 34.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
1.2 6.2 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
1.2 9.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
1.2 65.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
1.2 21.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
1.2 11.6 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
1.2 21.9 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
1.1 100.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
1.1 143.4 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
1.1 3.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
1.1 33.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
1.1 25.8 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
1.1 79.9 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
1.1 22.2 REACTOME KINESINS Genes involved in Kinesins
1.1 140.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
1.0 20.7 REACTOME DEADENYLATION DEPENDENT MRNA DECAY Genes involved in Deadenylation-dependent mRNA decay
1.0 18.3 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
1.0 23.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.9 26.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.9 9.0 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.9 3.5 REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX Genes involved in Assembly of the pre-replicative complex
0.9 23.9 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.8 60.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.8 15.4 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.8 2.4 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.8 22.8 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.8 15.6 REACTOME TRANSLATION Genes involved in Translation
0.8 14.4 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.7 17.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.7 7.8 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.7 36.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.7 10.9 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.7 11.5 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.6 12.8 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.6 8.9 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.6 27.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.6 56.5 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.6 2.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.5 17.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.5 8.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.5 8.9 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.5 13.9 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.5 75.8 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.5 4.9 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.5 7.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.4 12.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.4 5.0 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.4 9.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.4 10.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.4 6.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.4 4.0 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.4 8.7 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.3 7.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.3 4.1 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.3 4.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.2 6.1 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 3.4 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2 1.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 4.8 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 3.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 2.1 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.2 4.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.2 8.4 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.2 6.7 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 4.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.2 4.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.2 1.3 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 2.5 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.1 3.2 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 0.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 6.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.8 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.1 3.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 4.2 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 3.6 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.1 2.5 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 2.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 1.5 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 0.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 1.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.1 0.7 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 5.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 0.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.2 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.6 REACTOME MYOGENESIS Genes involved in Myogenesis