Project

avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for BATF3

Z-value: 1.05

Motif logo

logo of

Transcription factors associated with BATF3

Gene Symbol Gene ID Gene Info
BATF3
ENSG00000123685.9 BATF3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BATF3hg38_v1_chr1_-_212699817_212699846-0.091.9e-01Click!

Activity profile of BATF3 motif

Sorted Z-values of BATF3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of BATF3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr5_-_172771187 28.37 ENST00000239223.4
DUSP1
dual specificity phosphatase 1
chr6_+_139135063 10.77 ENST00000367658.3
HECA
hdc homolog, cell cycle regulator
chr12_-_122896066 9.40 ENST00000267202.7
ENST00000535765.5
VPS37B
VPS37B subunit of ESCRT-I
chr6_+_89081787 8.45 ENST00000354922.3
PNRC1
proline rich nuclear receptor coactivator 1
chr2_+_10044175 7.16 ENST00000440320.5
ENST00000535335.1
KLF11
Kruppel like factor 11
chr17_+_36103819 7.14 ENST00000615863.2
ENST00000621626.1
CCL4
C-C motif chemokine ligand 4
chr2_+_10043524 7.03 ENST00000305883.6
KLF11
Kruppel like factor 11
chr6_+_32972187 7.00 ENST00000607833.5
BRD2
bromodomain containing 2
chr1_+_1001002 6.88 ENST00000624697.4
ENST00000624652.1
ISG15
ISG15 ubiquitin like modifier
chr22_+_38201932 6.43 ENST00000538999.1
ENST00000538320.5
ENST00000338483.7
ENST00000441709.1
MAFF
MAF bZIP transcription factor F
chr5_-_176537361 5.77 ENST00000274811.9
RNF44
ring finger protein 44
chr11_+_102347312 5.25 ENST00000621637.1
ENST00000613397.4
BIRC2
baculoviral IAP repeat containing 2
chr11_+_102347205 5.16 ENST00000532832.5
ENST00000530675.5
ENST00000227758.7
ENST00000533742.5
ENST00000532672.5
ENST00000531259.5
ENST00000527465.1
BIRC2
baculoviral IAP repeat containing 2
chr6_-_90296824 4.75 ENST00000257749.9
BACH2
BTB domain and CNC homolog 2
chr14_-_49586325 4.58 ENST00000557519.1
ENST00000396020.7
ENST00000554075.2
ENST00000245458.11
RPS29
ribosomal protein S29
chr6_-_90296908 4.52 ENST00000537989.5
BACH2
BTB domain and CNC homolog 2
chr19_-_47113756 3.86 ENST00000253048.10
ZC3H4
zinc finger CCCH-type containing 4
chr3_+_38165484 3.80 ENST00000446845.5
ENST00000311806.8
OXSR1
oxidative stress responsive kinase 1
chr6_+_31971831 3.17 ENST00000375331.7
ENST00000375333.3
STK19
serine/threonine kinase 19
chr8_-_66178455 2.96 ENST00000276571.5
CRH
corticotropin releasing hormone
chr10_+_122163672 2.89 ENST00000369004.7
ENST00000260733.7
TACC2
transforming acidic coiled-coil containing protein 2
chr10_+_122163426 2.52 ENST00000360561.7
TACC2
transforming acidic coiled-coil containing protein 2
chr6_-_30556477 2.36 ENST00000376621.8
GNL1
G protein nucleolar 1 (putative)
chr10_+_122163590 2.27 ENST00000368999.5
TACC2
transforming acidic coiled-coil containing protein 2
chr3_-_101686690 2.12 ENST00000469605.1
ENST00000495401.5
ENST00000394077.8
RPL24
ribosomal protein L24
chrX_+_43654888 2.02 ENST00000542639.5
MAOA
monoamine oxidase A
chr1_+_156061142 1.97 ENST00000361084.10
RAB25
RAB25, member RAS oncogene family
chr9_-_97922487 1.88 ENST00000455506.1
ENST00000375117.8
ENST00000375119.8
ENST00000611338.4
TRMO
tRNA methyltransferase O
chr2_-_74529670 1.88 ENST00000377526.4
AUP1
AUP1 lipid droplet regulating VLDL assembly factor
chr22_+_31122923 1.80 ENST00000620191.4
ENST00000412277.6
ENST00000412985.5
ENST00000331075.10
ENST00000420017.5
ENST00000400294.6
ENST00000405300.5
ENST00000404390.7
INPP5J
inositol polyphosphate-5-phosphatase J
chr2_+_74530018 1.64 ENST00000437202.1
HTRA2
HtrA serine peptidase 2
chr2_+_69915041 1.59 ENST00000540449.5
MXD1
MAX dimerization protein 1
chr2_-_219399981 1.47 ENST00000519905.1
ENST00000523282.5
ENST00000434339.5
ENST00000457935.5
DNPEP
aspartyl aminopeptidase
chr3_-_52278620 1.35 ENST00000296490.8
WDR82
WD repeat domain 82
chr18_+_79069385 1.27 ENST00000426216.6
ENST00000307671.12
ENST00000586672.5
ENST00000586722.5
ATP9B
ATPase phospholipid transporting 9B (putative)
chr2_+_69915100 1.25 ENST00000264444.7
MXD1
MAX dimerization protein 1
chr1_+_153778178 1.24 ENST00000532853.5
SLC27A3
solute carrier family 27 member 3
chr15_-_48178144 1.19 ENST00000616409.4
ENST00000324324.12
ENST00000610570.4
MYEF2
myelin expression factor 2
chr2_+_74529923 1.18 ENST00000258080.8
ENST00000352222.7
HTRA2
HtrA serine peptidase 2
chr10_+_131900999 1.16 ENST00000455566.6
PPP2R2D
protein phosphatase 2 regulatory subunit Bdelta
chr6_+_37433197 1.11 ENST00000455891.5
ENST00000373451.9
CMTR1
cap methyltransferase 1
chr16_+_68023249 0.95 ENST00000358896.10
ENST00000568099.6
DUS2
dihydrouridine synthase 2
chr16_+_68023276 0.90 ENST00000567100.5
ENST00000565263.6
ENST00000432752.5
ENST00000569289.5
ENST00000564781.1
DUS2
dihydrouridine synthase 2
chr6_-_106325735 0.85 ENST00000635758.2
ENST00000369076.8
ENST00000636437.1
ATG5
autophagy related 5
chr11_-_85665077 0.79 ENST00000527447.2
CREBZF
CREB/ATF bZIP transcription factor
chr4_-_39366342 0.76 ENST00000503784.1
ENST00000349703.7
ENST00000381897.5
RFC1
replication factor C subunit 1
chr15_-_42548763 0.69 ENST00000563454.5
ENST00000397130.8
ENST00000570160.1
ENST00000323443.6
LRRC57
leucine rich repeat containing 57
chr15_+_42548810 0.61 ENST00000568876.5
ENST00000568846.6
ENST00000562398.5
ENST00000260372.8
HAUS2
HAUS augmin like complex subunit 2
chr6_-_106325416 0.61 ENST00000343245.7
ATG5
autophagy related 5
chr5_+_113513674 0.56 ENST00000161863.9
ENST00000515883.5
YTHDC2
YTH domain containing 2
chr4_-_2008835 0.45 ENST00000411649.3
ENST00000382882.9
ENST00000431323.6
NELFA
negative elongation factor complex member A
chr16_-_3018170 0.42 ENST00000572154.1
ENST00000328796.5
CLDN6
claudin 6
chr6_-_106325616 0.38 ENST00000360666.6
ATG5
autophagy related 5
chr20_+_43590912 0.36 ENST00000373030.8
ENST00000373039.4
IFT52
intraflagellar transport 52
chr14_+_67619911 0.33 ENST00000261783.4
ARG2
arginase 2
chr16_-_68023201 0.24 ENST00000332395.7
DDX28
DEAD-box helicase 28
chr6_-_31972123 0.22 ENST00000337523.10
DXO
decapping exoribonuclease
chr8_+_37736612 0.21 ENST00000518526.5
ENST00000523887.5
ENST00000648919.1
ENST00000519638.3
ERLIN2
ER lipid raft associated 2
chr3_-_119463606 0.17 ENST00000319172.10
ENST00000491685.5
ENST00000461654.1
TMEM39A
transmembrane protein 39A
chr6_-_31972290 0.10 ENST00000375349.7
DXO
decapping exoribonuclease
chr17_+_31094969 0.07 ENST00000431387.8
ENST00000358273.9
NF1
neurofibromin 1
chr17_-_51046868 0.02 ENST00000510283.5
ENST00000510855.1
SPAG9
sperm associated antigen 9
chr19_-_51002527 0.00 ENST00000595238.1
ENST00000600767.5
KLK8
kallikrein related peptidase 8

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.5 10.4 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
3.1 9.4 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
1.9 28.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
1.3 3.8 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
1.2 7.1 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
1.0 3.0 GO:0070093 positive regulation of corticotropin secretion(GO:0051461) positive regulation of cortisol secretion(GO:0051464) negative regulation of glucagon secretion(GO:0070093) cellular response to cocaine(GO:0071314)
0.9 8.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.9 6.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.7 2.8 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.6 1.8 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.4 2.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.3 14.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.3 1.8 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
0.2 6.4 GO:0007567 parturition(GO:0007567)
0.2 1.1 GO:0080009 mRNA methylation(GO:0080009)
0.1 1.3 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 2.0 GO:0042420 dopamine catabolic process(GO:0042420)
0.1 0.4 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 2.0 GO:0031268 pseudopodium organization(GO:0031268)
0.1 1.9 GO:0030488 tRNA methylation(GO:0030488)
0.1 1.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 7.0 GO:0006334 nucleosome assembly(GO:0006334)
0.1 0.2 GO:1902775 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 1.9 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.6 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 1.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 1.3 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.0 7.1 GO:0021987 cerebral cortex development(GO:0021987)
0.0 10.8 GO:0030323 respiratory tube development(GO:0030323)
0.0 0.2 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.8 GO:0070987 error-free translesion synthesis(GO:0070987)
0.0 4.6 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.3 GO:0000050 urea cycle(GO:0000050)
0.0 9.3 GO:1902593 single-organism nuclear import(GO:1902593)
0.0 2.4 GO:0002456 T cell mediated immunity(GO:0002456)
0.0 0.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 5.8 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process(GO:0043161)
0.0 0.2 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 9.4 GO:0000813 ESCRT I complex(GO:0000813)
0.7 13.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.6 3.0 GO:0043196 varicosity(GO:0043196)
0.4 1.9 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.4 1.8 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 9.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.3 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 0.8 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 2.0 GO:0031143 pseudopodium(GO:0031143)
0.1 0.6 GO:0070652 HAUS complex(GO:0070652)
0.1 0.4 GO:0032021 NELF complex(GO:0032021)
0.1 4.6 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 8.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.4 GO:0044292 dendrite terminus(GO:0044292)
0.0 1.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 14.2 GO:0005925 focal adhesion(GO:0005925)
0.0 0.4 GO:0016327 apicolateral plasma membrane(GO:0016327)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
9.5 28.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
2.6 10.4 GO:0098770 FBXO family protein binding(GO:0098770)
1.4 7.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.8 9.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.5 6.9 GO:0031386 protein tag(GO:0031386)
0.5 1.9 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.4 1.8 GO:0019776 Atg8 ligase activity(GO:0019776)
0.3 1.8 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 1.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.2 2.0 GO:0008131 primary amine oxidase activity(GO:0008131)
0.2 1.8 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445) phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.2 7.0 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.2 1.9 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 0.8 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 9.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 1.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.1 3.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 1.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 1.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 1.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.2 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.0 1.0 GO:0031489 myosin V binding(GO:0031489)
0.0 7.7 GO:0035257 nuclear hormone receptor binding(GO:0035257)
0.0 3.8 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 6.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 5.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 22.9 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 2.8 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.2 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 28.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.3 10.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 7.1 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 7.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 2.8 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.2 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 0.8 PID FAS PATHWAY FAS (CD95) signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 9.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 10.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.2 8.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 7.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 2.0 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 4.6 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 6.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 1.8 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 3.0 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 1.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 2.1 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions