Project

avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for BCL6B

Z-value: 1.09

Motif logo

logo of

Transcription factors associated with BCL6B

Gene Symbol Gene ID Gene Info
BCL6B
ENSG00000161940.11 BCL6B

Activity profile of BCL6B motif

Sorted Z-values of BCL6B motif

Network of associatons between targets according to the STRING database.

First level regulatory network of BCL6B

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:

Promoter Score Transcript Gene Gene Info
chr3_-_149377637 16.14 ENST00000305366.8
TM4SF1
transmembrane 4 L six family member 1
chr2_-_215393126 12.59 ENST00000456923.5
FN1
fibronectin 1
chr20_+_11892493 11.84 ENST00000422390.5
ENST00000618918.4
BTBD3
BTB domain containing 3
chr9_-_115118145 11.25 ENST00000350763.9
TNC
tenascin C
chr9_-_115118198 11.12 ENST00000534839.1
ENST00000535648.5
TNC
tenascin C
chr2_-_175005357 9.05 ENST00000409156.7
ENST00000444573.2
ENST00000409900.9
CHN1
chimerin 1
chr2_-_55010348 8.29 ENST00000394609.6
RTN4
reticulon 4
chr12_+_103930600 8.00 ENST00000680316.1
ENST00000679861.1
HSP90B1
heat shock protein 90 beta family member 1
chr1_-_108192818 7.37 ENST00000370041.4
SLC25A24
solute carrier family 25 member 24
chr9_-_110256466 6.97 ENST00000374515.9
ENST00000374517.6
TXN
thioredoxin
chr12_+_103930332 6.75 ENST00000681861.1
ENST00000550595.2
ENST00000680762.1
ENST00000614327.2
ENST00000681949.1
ENST00000299767.10
HSP90B1
heat shock protein 90 beta family member 1
chr7_+_134779663 6.74 ENST00000361901.6
CALD1
caldesmon 1
chr7_+_134779625 6.59 ENST00000454108.5
ENST00000361675.7
CALD1
caldesmon 1
chr1_+_84144260 6.58 ENST00000370685.7
PRKACB
protein kinase cAMP-activated catalytic subunit beta
chr17_-_50397472 6.42 ENST00000576448.1
ENST00000225972.8
LRRC59
leucine rich repeat containing 59
chr7_+_832488 6.35 ENST00000405266.5
ENST00000403868.5
ENST00000425407.6
SUN1
Sad1 and UNC84 domain containing 1
chr7_+_832470 6.24 ENST00000401592.6
SUN1
Sad1 and UNC84 domain containing 1
chr3_+_159069252 6.10 ENST00000640015.1
ENST00000476809.7
ENST00000485419.7
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr15_+_65550819 5.51 ENST00000569894.5
HACD3
3-hydroxyacyl-CoA dehydratase 3
chr1_-_209652329 5.50 ENST00000367030.7
ENST00000356082.9
LAMB3
laminin subunit beta 3
chr12_+_19205294 5.30 ENST00000424268.5
PLEKHA5
pleckstrin homology domain containing A5
chr13_-_36131286 5.20 ENST00000255448.8
ENST00000379892.4
DCLK1
doublecortin like kinase 1
chr2_+_188292771 5.16 ENST00000359135.7
GULP1
GULP PTB domain containing engulfment adaptor 1
chr2_+_188292814 5.11 ENST00000409580.5
ENST00000409637.7
GULP1
GULP PTB domain containing engulfment adaptor 1
chr3_+_124384513 4.23 ENST00000682540.1
ENST00000522553.6
ENST00000682695.1
ENST00000682674.1
ENST00000684382.1
KALRN
kalirin RhoGEF kinase
chr3_-_123884290 3.80 ENST00000346322.9
ENST00000360772.7
ENST00000360304.8
MYLK
myosin light chain kinase
chr2_-_187554351 3.52 ENST00000437725.5
ENST00000409676.5
ENST00000233156.9
ENST00000339091.8
ENST00000420747.1
TFPI
tissue factor pathway inhibitor
chr8_-_140800535 3.51 ENST00000521986.5
ENST00000523539.5
PTK2
protein tyrosine kinase 2
chr3_+_124384950 3.40 ENST00000683146.1
KALRN
kalirin RhoGEF kinase
chr2_-_144430934 3.33 ENST00000638087.1
ENST00000638007.1
ZEB2
zinc finger E-box binding homeobox 2
chr5_-_141320755 3.17 ENST00000624761.1
ENST00000313368.8
TAF7
TATA-box binding protein associated factor 7
chr1_+_193060034 2.98 ENST00000367446.7
ENST00000367443.5
ENST00000367444.7
ENST00000367445.7
RO60
Ro60, Y RNA binding protein
chr1_-_150697128 2.84 ENST00000427665.1
ENST00000271732.8
GOLPH3L
golgi phosphoprotein 3 like
chr12_-_120250145 2.83 ENST00000458477.6
PXN
paxillin
chr1_-_211830748 2.76 ENST00000366997.9
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr3_+_124384757 2.73 ENST00000684374.1
KALRN
kalirin RhoGEF kinase
chr7_-_30550761 2.68 ENST00000598361.4
ENST00000440438.6
ENSG00000281039.1
GARS1-DT
novel protein
GARS1 divergent transcript
chr6_+_39792298 2.62 ENST00000633794.1
ENST00000274867.9
DAAM2
dishevelled associated activator of morphogenesis 2
chr15_+_66453418 2.57 ENST00000566326.1
MAP2K1
mitogen-activated protein kinase kinase 1
chr12_-_49187369 2.44 ENST00000547939.6
TUBA1A
tubulin alpha 1a
chr11_-_95910665 2.39 ENST00000674610.1
ENST00000675660.1
MTMR2
myotubularin related protein 2
chr11_+_73647549 2.38 ENST00000227214.10
ENST00000398494.8
ENST00000543085.5
PLEKHB1
pleckstrin homology domain containing B1
chr11_-_95910824 2.36 ENST00000674528.1
ENST00000675477.1
ENST00000675636.1
MTMR2
myotubularin related protein 2
chr18_+_3252267 2.35 ENST00000536605.1
ENST00000580887.5
MYL12A
myosin light chain 12A
chr10_-_60733467 2.33 ENST00000373827.6
ANK3
ankyrin 3
chr7_-_23347704 2.33 ENST00000619562.4
IGF2BP3
insulin like growth factor 2 mRNA binding protein 3
chr13_-_36131352 2.13 ENST00000360631.8
DCLK1
doublecortin like kinase 1
chr11_-_95910748 2.07 ENST00000675933.1
MTMR2
myotubularin related protein 2
chr2_+_69893940 2.03 ENST00000244227.8
ENST00000409116.5
SNRNP27
small nuclear ribonucleoprotein U4/U6.U5 subunit 27
chr18_+_74499861 1.98 ENST00000324301.12
CNDP2
carnosine dipeptidase 2
chr14_+_94612383 1.91 ENST00000393080.8
ENST00000555820.1
ENST00000393078.5
ENST00000467132.5
SERPINA3
serpin family A member 3
chr15_+_44711487 1.79 ENST00000544417.5
ENST00000559916.1
ENST00000648006.3
B2M
beta-2-microglobulin
chr11_-_65557740 1.77 ENST00000526927.5
LTBP3
latent transforming growth factor beta binding protein 3
chr1_-_53940100 1.66 ENST00000371376.1
HSPB11
heat shock protein family B (small) member 11
chr16_-_82170175 1.62 ENST00000563504.5
ENST00000569021.1
ENST00000258169.9
MPHOSPH6
M-phase phosphoprotein 6
chr1_+_235367360 1.52 ENST00000651186.1
ENST00000406207.5
ENST00000645899.1
ENST00000644578.1
ENST00000645372.1
ENST00000647407.1
ENST00000642610.2
ENST00000543662.4
ENST00000366601.8
TBCE
tubulin folding cofactor E
chr9_-_96383675 1.50 ENST00000375257.2
ENST00000375259.9
ENST00000253270.13
SLC35D2
solute carrier family 35 member D2
chr8_-_101204697 1.48 ENST00000517844.5
ZNF706
zinc finger protein 706
chr10_+_11165475 1.45 ENST00000609692.5
ENST00000354897.3
CELF2
CUGBP Elav-like family member 2
chr17_-_78187036 1.43 ENST00000590862.5
ENST00000590430.5
ENST00000301634.12
ENST00000586613.1
TK1
thymidine kinase 1
chr11_+_59144767 1.38 ENST00000527629.6
ENST00000361723.7
ENST00000531408.6
ENST00000420244.6
FAM111A
FAM111 trypsin like peptidase A
chr4_+_26319636 1.34 ENST00000342295.6
ENST00000506956.5
ENST00000512671.6
ENST00000345843.8
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr18_-_27990256 1.29 ENST00000675173.1
CDH2
cadherin 2
chr15_+_49621004 1.23 ENST00000403028.8
ENST00000558653.5
ENST00000559164.5
ENST00000560632.5
ENST00000559405.5
ENST00000251250.7
DTWD1
DTW domain containing 1
chr10_+_110964125 1.21 ENST00000265277.9
SHOC2
SHOC2 leucine rich repeat scaffold protein
chr15_-_64381431 1.21 ENST00000558008.3
ENST00000300035.9
ENST00000559519.5
ENST00000380258.6
PCLAF
PCNA clamp associated factor
chr2_+_66435116 1.19 ENST00000272369.14
ENST00000560281.6
MEIS1
Meis homeobox 1
chr8_-_90082871 1.14 ENST00000265431.7
CALB1
calbindin 1
chr19_-_46471484 1.12 ENST00000313683.15
ENST00000602246.1
PNMA8A
PNMA family member 8A
chr4_-_88231322 1.08 ENST00000515655.5
ABCG2
ATP binding cassette subfamily G member 2 (Junior blood group)
chr11_+_27041313 1.03 ENST00000528583.5
BBOX1
gamma-butyrobetaine hydroxylase 1
chr2_+_172821575 1.03 ENST00000397087.7
RAPGEF4
Rap guanine nucleotide exchange factor 4
chr19_+_11089446 0.99 ENST00000557933.5
ENST00000455727.6
ENST00000535915.5
ENST00000545707.5
ENST00000558518.6
ENST00000558013.5
LDLR
low density lipoprotein receptor
chr19_+_44643902 0.95 ENST00000403059.8
ENST00000425690.8
PVR
PVR cell adhesion molecule
chr6_+_44227025 0.94 ENST00000371708.1
SLC29A1
solute carrier family 29 member 1 (Augustine blood group)
chr1_+_209704836 0.87 ENST00000367027.5
HSD11B1
hydroxysteroid 11-beta dehydrogenase 1
chr6_+_101181254 0.83 ENST00000682090.1
ENST00000421544.6
GRIK2
glutamate ionotropic receptor kainate type subunit 2
chr16_-_67483541 0.82 ENST00000290953.3
AGRP
agouti related neuropeptide
chrX_+_96684638 0.80 ENST00000355827.8
ENST00000373061.7
DIAPH2
diaphanous related formin 2
chr1_-_230714112 0.68 ENST00000681514.1
ENST00000366667.6
ENST00000680041.1
AGT
angiotensinogen
chr9_-_92482350 0.62 ENST00000375543.2
ASPN
asporin
chr3_+_23916979 0.58 ENST00000434031.6
ENST00000307839.10
ENST00000413699.7
ENST00000645079.1
ENST00000456530.7
ENST00000412097.5
ENST00000644684.1
ENST00000415719.5
ENST00000644185.1
ENST00000436146.2
RPL15
ribosomal protein L15
chr19_-_13116649 0.57 ENST00000437766.5
ENST00000221504.12
TRMT1
tRNA methyltransferase 1
chr14_-_29927801 0.57 ENST00000331968.11
PRKD1
protein kinase D1
chr2_-_187554473 0.53 ENST00000453013.5
ENST00000417013.5
TFPI
tissue factor pathway inhibitor
chr11_-_18236795 0.51 ENST00000278222.7
SAA4
serum amyloid A4, constitutive
chr9_+_85941121 0.50 ENST00000361671.10
NAA35
N-alpha-acetyltransferase 35, NatC auxiliary subunit
chr12_+_69738853 0.44 ENST00000247833.12
ENST00000378815.10
ENST00000483530.6
RAB3IP
RAB3A interacting protein
chr19_+_44644025 0.42 ENST00000406449.8
PVR
PVR cell adhesion molecule
chr19_-_13116719 0.41 ENST00000588229.1
ENST00000357720.9
TRMT1
tRNA methyltransferase 1
chrX_-_31266925 0.40 ENST00000680557.1
ENST00000378680.6
ENST00000378723.7
ENST00000680768.2
ENST00000681870.1
ENST00000680355.1
ENST00000682322.1
ENST00000682600.1
ENST00000680162.2
ENST00000681153.1
ENST00000681334.1
DMD
dystrophin
chr15_-_75579248 0.38 ENST00000306726.6
ENST00000618819.5
PTPN9
protein tyrosine phosphatase non-receptor type 9
chr10_-_72216267 0.37 ENST00000342444.8
ENST00000533958.1
ENST00000672957.1
ENST00000527593.5
ENST00000672940.1
ENST00000530461.5
ENST00000317168.11
ENST00000524829.5
ASCC1
activating signal cointegrator 1 complex subunit 1
chr12_-_91180365 0.37 ENST00000547937.5
DCN
decorin
chr15_+_74318553 0.35 ENST00000558821.5
ENST00000268082.4
CCDC33
coiled-coil domain containing 33
chr11_-_49208589 0.30 ENST00000256999.7
FOLH1
folate hydrolase 1
chr11_+_124115404 0.29 ENST00000361352.9
ENST00000449321.5
ENST00000392748.5
ENST00000392744.4
ENST00000456829.7
VWA5A
von Willebrand factor A domain containing 5A
chr3_+_23917693 0.29 ENST00000354811.5
RPL15
ribosomal protein L15
chr12_-_10849464 0.26 ENST00000544994.5
ENST00000228811.8
ENST00000540107.2
PRR4
proline rich 4
chr12_-_124495252 0.26 ENST00000405201.5
NCOR2
nuclear receptor corepressor 2
chr11_-_49208532 0.19 ENST00000356696.7
FOLH1
folate hydrolase 1
chr6_+_31620701 0.18 ENST00000376033.3
ENST00000376007.8
PRRC2A
proline rich coiled-coil 2A
chr12_-_122500924 0.16 ENST00000633063.3
ZCCHC8
zinc finger CCHC-type containing 8
chr11_-_49208619 0.14 ENST00000340334.11
FOLH1
folate hydrolase 1
chr6_-_29375291 0.11 ENST00000396806.3
OR12D3
olfactory receptor family 12 subfamily D member 3
chr1_-_168729187 0.11 ENST00000367817.4
DPT
dermatopontin
chrX_+_96684712 0.09 ENST00000373049.8
DIAPH2
diaphanous related formin 2
chr4_-_98657635 0.08 ENST00000515287.5
ENST00000511651.5
ENST00000505184.5
TSPAN5
tetraspanin 5
chr17_+_82830496 0.06 ENST00000683821.1
TBCD
tubulin folding cofactor D
chr1_-_153549120 0.05 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr13_+_72782116 0.02 ENST00000326291.11
ENST00000617689.4
PIBF1
progesterone immunomodulatory binding factor 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.5 22.4 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
4.2 12.6 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
2.5 12.6 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
1.2 10.4 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
1.1 6.6 GO:0097338 response to clozapine(GO:0097338)
1.1 7.4 GO:0015866 ADP transport(GO:0015866)
1.0 7.0 GO:0006662 glycerol ether metabolic process(GO:0006662)
0.9 14.8 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.8 8.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.8 5.5 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.6 3.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.6 6.8 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.6 1.8 GO:1904440 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) cellular response to iron(III) ion(GO:0071283) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.6 1.8 GO:1902462 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.6 2.3 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.4 4.0 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.4 3.3 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.4 2.6 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.3 1.0 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.3 3.2 GO:0015846 polyamine transport(GO:0015846)
0.3 1.5 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.3 6.3 GO:0007172 signal complex assembly(GO:0007172)
0.3 2.8 GO:0048194 Golgi vesicle budding(GO:0048194)
0.2 9.0 GO:0008045 motor neuron axon guidance(GO:0008045)
0.2 1.4 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.2 0.7 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.2 1.5 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.2 5.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 1.3 GO:0072554 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) blood vessel lumenization(GO:0072554) blood vessel endothelial cell fate specification(GO:0097101) positive regulation of ephrin receptor signaling pathway(GO:1901189) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.2 0.9 GO:0015862 uridine transport(GO:0015862)
0.2 7.3 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.2 2.8 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.1 1.3 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 1.4 GO:0046125 thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.1 1.1 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 1.1 GO:0015886 heme transport(GO:0015886)
0.1 1.7 GO:0070986 left/right axis specification(GO:0070986)
0.1 0.6 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 1.0 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.8 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.1 2.0 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 1.9 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.6 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 1.5 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 0.3 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 11.3 GO:0021987 cerebral cortex development(GO:0021987)
0.1 0.6 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 1.2 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1 7.2 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.1 0.8 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.4 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 1.6 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.0 1.0 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.9 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 1.5 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.4 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 2.2 GO:0007602 phototransduction(GO:0007602)
0.0 14.7 GO:0006936 muscle contraction(GO:0006936)
0.0 0.5 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 2.6 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 1.2 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 1.4 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 2.3 GO:0051028 mRNA transport(GO:0051028)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 22.4 GO:0005614 interstitial matrix(GO:0005614)
1.0 14.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
1.0 11.8 GO:0005577 fibrinogen complex(GO:0005577)
1.0 12.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.9 13.3 GO:0030478 actin cap(GO:0030478)
0.8 5.5 GO:0005610 laminin-5 complex(GO:0005610)
0.4 1.8 GO:0031905 early endosome lumen(GO:0031905)
0.3 8.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.3 6.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 3.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.2 11.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 1.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 6.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 1.0 GO:0097443 sorting endosome(GO:0097443)
0.1 10.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 2.3 GO:0043194 spectrin-associated cytoskeleton(GO:0014731) axon initial segment(GO:0043194)
0.1 1.7 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.3 GO:0005916 fascia adherens(GO:0005916) catenin complex(GO:0016342)
0.1 22.4 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 0.5 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.8 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 2.8 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 5.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 0.4 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 2.3 GO:0016459 myosin complex(GO:0016459)
0.0 1.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.4 GO:0031527 filopodium membrane(GO:0031527)
0.0 1.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.1 GO:0043195 terminal bouton(GO:0043195)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 2.0 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.4 GO:0031672 A band(GO:0031672)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.5 22.4 GO:0045545 syndecan binding(GO:0045545)
1.2 7.0 GO:0047134 protein-disulfide reductase activity(GO:0047134)
1.1 7.4 GO:0005347 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
1.0 13.5 GO:0046790 virion binding(GO:0046790)
0.9 3.8 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.8 3.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.8 5.5 GO:0102344 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.6 12.6 GO:0043495 protein anchor(GO:0043495)
0.5 13.3 GO:0005523 tropomyosin binding(GO:0005523)
0.4 5.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.4 6.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 1.0 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.3 10.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.3 6.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.3 2.8 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.3 0.9 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 2.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2 1.4 GO:0004797 thymidine kinase activity(GO:0004797)
0.2 1.0 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.2 12.6 GO:0016504 peptidase activator activity(GO:0016504)
0.2 9.0 GO:0046875 ephrin receptor binding(GO:0046875)
0.2 1.5 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.2 3.5 GO:0008432 JUN kinase binding(GO:0008432)
0.2 1.1 GO:0005499 vitamin D binding(GO:0005499)
0.2 0.6 GO:1904493 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.1 1.1 GO:0015232 heme transporter activity(GO:0015232)
0.1 1.0 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 3.2 GO:0017166 vinculin binding(GO:0017166)
0.1 2.0 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 1.3 GO:0000150 recombinase activity(GO:0000150)
0.1 0.9 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 2.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 1.3 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 3.3 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 1.8 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 5.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 17.4 GO:0031625 ubiquitin protein ligase binding(GO:0031625)
0.0 2.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 3.5 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 1.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.6 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.0 GO:0030552 cAMP binding(GO:0030552)
0.0 1.6 GO:0051087 chaperone binding(GO:0051087)
0.0 6.8 GO:0045296 cadherin binding(GO:0045296)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 1.4 GO:0001618 virus receptor activity(GO:0001618)
0.0 1.2 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.5 GO:0042056 chemoattractant activity(GO:0042056)
0.0 1.2 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 1.0 GO:0005518 collagen binding(GO:0005518)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 37.8 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.3 10.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.2 4.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 7.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.2 10.3 PID ARF6 PATHWAY Arf6 signaling events
0.2 2.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.2 10.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.2 14.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.2 9.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 4.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 7.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 3.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 1.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.6 PID IGF1 PATHWAY IGF1 pathway
0.0 1.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.0 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 1.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.4 PID E2F PATHWAY E2F transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 14.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.6 15.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.4 6.8 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.4 7.0 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.3 17.1 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 21.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 2.6 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.2 7.6 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.2 1.8 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 2.8 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.2 18.7 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.1 4.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 4.0 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1 1.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 2.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 5.0 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.1 2.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 2.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 6.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 2.2 REACTOME DIABETES PATHWAYS Genes involved in Diabetes pathways
0.0 0.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones