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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for CCAGUGU

Z-value: 2.11

Motif logo

miRNA associated with seed CCAGUGU

NamemiRBASE accession
MIMAT0000231
MIMAT0000263

Activity profile of CCAGUGU motif

Sorted Z-values of CCAGUGU motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CCAGUGU

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_+_183023409 12.75 ENST00000258341.5
laminin subunit gamma 1
chrX_-_100636799 10.57 ENST00000373020.9
tetraspanin 6
chr12_+_12891554 10.41 ENST00000014914.6
G protein-coupled receptor class C group 5 member A
chr7_+_116525524 10.33 ENST00000405348.6
caveolin 1
chr14_+_61695777 9.65 ENST00000323441.10
hypoxia inducible factor 1 subunit alpha
chr8_+_103298836 8.77 ENST00000523739.5
ENST00000358755.5
frizzled class receptor 6
chr9_+_107283256 7.96 ENST00000358015.8
RAD23 homolog B, nucleotide excision repair protein
chr9_-_125241327 7.76 ENST00000324460.7
ENST00000680272.1
ENST00000680032.1
heat shock protein family A (Hsp70) member 5
chr15_-_34101807 7.57 ENST00000527822.5
ENST00000528949.1
ENST00000256545.9
ER membrane protein complex subunit 7
chr22_-_36387949 6.61 ENST00000216181.11
myosin heavy chain 9
chr7_+_101127095 6.41 ENST00000223095.5
serpin family E member 1
chr6_+_21593742 6.25 ENST00000244745.4
SRY-box transcription factor 4
chr9_-_125189721 6.15 ENST00000456642.1
ENST00000373547.9
ENST00000415905.5
ENST00000451402.5
protein phosphatase 6 catalytic subunit
chr17_-_4366616 5.99 ENST00000572484.5
ENST00000396981.7
ubiquitin conjugating enzyme E2 G1
chr2_-_241272812 5.86 ENST00000427007.5
ENST00000458564.5
ENST00000452065.5
ENST00000427183.6
ENST00000426343.5
ENST00000422080.5
ENST00000449504.5
ENST00000449864.5
ENST00000391975.5
high density lipoprotein binding protein
chr11_-_102452758 5.74 ENST00000398136.7
ENST00000361236.7
transmembrane protein 123
chr12_+_71754834 5.72 ENST00000261263.5
RAB21, member RAS oncogene family
chr10_-_96586975 5.46 ENST00000371142.9
transmembrane 9 superfamily member 3
chr2_-_152717966 5.42 ENST00000410080.8
pre-mRNA processing factor 40 homolog A
chr2_-_46941760 5.25 ENST00000444761.6
ENST00000409147.1
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chr1_+_193121950 4.92 ENST00000367435.5
cell division cycle 73
chr8_-_13514821 4.61 ENST00000276297.9
DLC1 Rho GTPase activating protein
chr2_+_36355712 4.47 ENST00000280527.7
cysteine rich transmembrane BMP regulator 1
chr10_-_119536533 4.42 ENST00000392865.5
regulator of G protein signaling 10
chr3_-_190120881 4.36 ENST00000319332.10
prolyl 3-hydroxylase 2
chr2_+_99337364 4.32 ENST00000617677.1
ENST00000289371.11
eukaryotic translation initiation factor 5B
chr19_+_44809089 4.30 ENST00000270233.12
ENST00000591520.6
basal cell adhesion molecule (Lutheran blood group)
chr12_-_92145838 4.24 ENST00000256015.5
BTG anti-proliferation factor 1
chrX_+_23783163 4.21 ENST00000379254.5
ENST00000379270.5
ENST00000683890.1
spermidine/spermine N1-acetyltransferase 1
novel protein
chr11_+_34051722 4.14 ENST00000341394.9
ENST00000389645.7
cell cycle associated protein 1
chr17_-_48604959 3.99 ENST00000225648.4
ENST00000484302.3
homeobox B6
chr1_-_94237562 3.92 ENST00000260526.11
ENST00000370217.3
Rho GTPase activating protein 29
chr20_-_10673987 3.90 ENST00000254958.10
jagged canonical Notch ligand 1
chr3_-_160565560 3.76 ENST00000334256.9
ENST00000676866.1
ENST00000469804.1
karyopherin subunit alpha 4
chr10_+_69124152 3.72 ENST00000395098.5
ENST00000263559.11
VPS26, retromer complex component A
chr11_-_57530714 3.54 ENST00000525158.1
ENST00000257245.9
ENST00000525587.1
translocase of inner mitochondrial membrane 10
chr3_+_180912656 3.53 ENST00000357559.9
ENST00000491062.5
ENST00000468861.5
ENST00000445140.6
ENST00000484958.5
FMR1 autosomal homolog 1
chr10_+_58512864 3.51 ENST00000373886.8
BicC family RNA binding protein 1
chr1_-_38859669 3.45 ENST00000373001.4
Ras related GTP binding C
chrX_-_74614612 3.45 ENST00000349225.2
ENST00000332687.11
ring finger protein, LIM domain interacting
chr1_-_84506565 3.44 ENST00000370641.3
ENST00000370645.9
G protein subunit gamma 5
chr8_+_23528947 3.42 ENST00000519973.6
solute carrier family 25 member 37
chr9_-_91423819 3.40 ENST00000297689.4
nuclear factor, interleukin 3 regulated
chr16_-_50368920 3.33 ENST00000394688.8
bromodomain containing 7
chr20_+_19758245 3.26 ENST00000255006.12
Ras and Rab interactor 2
chr11_+_87037820 3.12 ENST00000340353.11
transmembrane protein 135
chr6_+_30888672 3.08 ENST00000446312.5
discoidin domain receptor tyrosine kinase 1
chr19_-_11197516 2.97 ENST00000592903.5
ENST00000586659.6
ENST00000589359.5
ENST00000588724.5
KN motif and ankyrin repeat domains 2
chr8_+_97869040 2.94 ENST00000254898.7
ENST00000524308.5
ENST00000522025.6
matrilin 2
chr11_-_65614195 2.89 ENST00000309100.8
ENST00000529839.1
ENST00000526293.1
mitogen-activated protein kinase kinase kinase 11
chr4_+_139301478 2.88 ENST00000296543.10
ENST00000398947.1
N-alpha-acetyltransferase 15, NatA auxiliary subunit
chr1_+_51236252 2.87 ENST00000242719.4
ring finger protein 11
chr14_+_20469399 2.81 ENST00000361505.10
ENST00000553591.1
purine nucleoside phosphorylase
chr15_-_77071099 2.78 ENST00000267970.9
ENST00000346495.6
ENST00000424443.7
ENST00000561277.5
tetraspanin 3
chr12_-_120250145 2.77 ENST00000458477.6
paxillin
chr11_+_63938971 2.69 ENST00000539656.5
ENST00000377793.9
N-alpha-acetyltransferase 40, NatD catalytic subunit
chr9_+_128683645 2.65 ENST00000372692.8
SET nuclear proto-oncogene
chr22_-_37019434 2.63 ENST00000249042.8
ENST00000403892.7
thiosulfate sulfurtransferase
chr5_-_83720813 2.60 ENST00000515590.1
ENST00000274341.9
hyaluronan and proteoglycan link protein 1
chr17_+_57085092 2.59 ENST00000575322.1
ENST00000337714.8
A-kinase anchoring protein 1
chr12_-_14803462 2.58 ENST00000261167.7
ENST00000535328.1
WW domain binding protein 11
chr5_+_154941063 2.50 ENST00000523037.6
ENST00000265229.12
ENST00000439747.7
ENST00000522038.5
mitochondrial ribosomal protein L22
chr14_-_34630109 2.48 ENST00000396526.7
sorting nexin 6
chr10_-_45535346 2.45 ENST00000453424.7
ENST00000395769.6
membrane associated ring-CH-type finger 8
chr3_-_177196451 2.44 ENST00000430069.5
ENST00000630796.2
ENST00000428970.5
TBL1X receptor 1
chr2_+_169733811 2.41 ENST00000392647.7
kelch like family member 23
chr11_-_27506751 2.39 ENST00000278193.7
ENST00000524596.1
lin-7 homolog C, crumbs cell polarity complex component
chr10_+_110919595 2.36 ENST00000369452.9
SHOC2 leucine rich repeat scaffold protein
chr10_-_100185993 2.35 ENST00000421367.7
ENST00000370408.2
ENST00000407654.7
ER lipid raft associated 1
chr9_-_35732122 2.33 ENST00000314888.10
talin 1
chr15_-_41972504 2.31 ENST00000220325.9
EH domain containing 4
chr16_-_4937064 2.31 ENST00000590782.6
ENST00000345988.7
periplakin
chr5_+_180494430 2.29 ENST00000393356.7
ENST00000618123.4
CCR4-NOT transcription complex subunit 6
chrX_-_77895546 2.24 ENST00000358075.11
magnesium transporter 1
chr1_+_218345326 2.24 ENST00000366930.9
transforming growth factor beta 2
chr20_-_63969890 2.09 ENST00000369888.6
zinc finger protein 512B
chr16_+_15949549 2.08 ENST00000399408.7
ENST00000572882.3
ENST00000677164.1
ATP binding cassette subfamily C member 1
chr14_+_49893055 2.08 ENST00000298316.7
ADP ribosylation factor 6
chr10_-_70170466 2.07 ENST00000373239.2
ENST00000373241.9
ENST00000373242.6
secretion associated Ras related GTPase 1A
chr21_+_38805165 2.06 ENST00000360214.8
ETS proto-oncogene 2, transcription factor
chr10_+_87504867 2.03 ENST00000371994.8
multiple inositol-polyphosphate phosphatase 1
chr1_+_147928420 2.00 ENST00000314163.12
ENST00000468618.6
G protein-coupled receptor 89B
chr1_+_19644284 2.00 ENST00000375136.8
NBL1, DAN family BMP antagonist
chr13_-_35476682 1.99 ENST00000379919.6
mab-21 like 1
chr14_+_67241417 1.97 ENST00000556345.6
ENST00000555925.5
ENST00000261681.9
ENST00000557783.1
membrane palmitoylated protein 5
chr2_-_39437264 1.97 ENST00000263881.8
ENST00000341681.9
mitogen-activated protein kinase kinase kinase kinase 3
chr2_-_183038405 1.93 ENST00000361354.9
NCK associated protein 1
chr3_+_97821984 1.91 ENST00000389622.7
crystallin beta-gamma domain containing 3
chr12_+_101877571 1.89 ENST00000258534.13
DNA damage regulated autophagy modulator 1
chr8_+_143597814 1.88 ENST00000504548.4
tigger transposable element derived 5
chr1_+_218285283 1.84 ENST00000366932.4
ribosomal RNA processing 15 homolog
chr8_+_69466617 1.83 ENST00000525061.5
ENST00000260128.8
ENST00000458141.6
sulfatase 1
chr22_-_18024513 1.83 ENST00000441493.7
microtubule associated monooxygenase, calponin and LIM domain containing 3
chr11_-_62646598 1.80 ENST00000648273.1
ENST00000356638.8
ENST00000346178.8
ENST00000534779.5
ENST00000525994.1
ENST00000540933.5
glucosidase II alpha subunit
chr1_+_145607978 1.78 ENST00000313835.14
ENST00000534502.5
G protein-coupled receptor 89A
chr8_-_121641424 1.77 ENST00000303924.5
hyaluronan synthase 2
chrX_+_41334154 1.75 ENST00000441189.4
ENST00000644513.1
ENST00000644109.1
ENST00000646122.1
ENST00000644074.1
ENST00000644876.2
ENST00000399959.7
ENST00000646319.1
DEAD-box helicase 3 X-linked
chr11_+_9664061 1.74 ENST00000447399.6
ENST00000318950.11
switching B cell complex subunit SWAP70
chr17_+_47649899 1.72 ENST00000290158.9
karyopherin subunit beta 1
chr12_+_109097568 1.72 ENST00000242576.7
uracil DNA glycosylase
chr3_-_157160094 1.69 ENST00000295925.5
ENST00000295926.8
cyclin L1
chr1_+_35883189 1.67 ENST00000674304.1
ENST00000373204.6
ENST00000674426.1
argonaute RISC component 1
chr11_+_12377524 1.66 ENST00000334956.15
parvin alpha
chrX_+_68499021 1.65 ENST00000462683.6
Yip1 domain family member 6
chr18_-_21111778 1.64 ENST00000399799.3
Rho associated coiled-coil containing protein kinase 1
chr19_+_57363469 1.63 ENST00000282282.4
ENST00000543226.2
ENST00000596755.1
ENST00000597658.1
zinc finger protein 547
trafficking protein particle complex 2B
novel protein
chr8_+_30384511 1.58 ENST00000339877.8
ENST00000320203.8
ENST00000287771.9
ENST00000397323.9
RNA binding protein, mRNA processing factor
chr6_+_43770707 1.58 ENST00000324450.11
ENST00000417285.7
ENST00000413642.8
ENST00000372055.9
ENST00000482630.7
ENST00000425836.7
ENST00000372064.9
ENST00000372077.8
ENST00000519767.5
vascular endothelial growth factor A
chr11_-_79441016 1.54 ENST00000278550.12
teneurin transmembrane protein 4
chr14_-_55411817 1.49 ENST00000247178.6
autophagy related 14
chr22_+_29883158 1.48 ENST00000333027.7
ENST00000401950.7
ENST00000445401.5
ENST00000323630.9
ENST00000351488.7
myotubularin related protein 3
chr20_+_11890723 1.48 ENST00000254977.7
BTB domain containing 3
chr17_+_30477362 1.42 ENST00000225724.9
ENST00000451249.7
ENST00000467337.6
ENST00000581721.5
ENST00000414833.2
golgi SNAP receptor complex member 1
chr14_+_75002903 1.40 ENST00000266126.10
eukaryotic translation initiation factor 2B subunit beta
chr10_-_86521737 1.37 ENST00000298767.10
WAPL cohesin release factor
chr17_+_38870050 1.37 ENST00000318008.11
ENST00000435347.7
LIM and SH3 protein 1
chr19_+_34254543 1.36 ENST00000588470.5
ENST00000299505.8
ENST00000589583.5
granule associated Rac and RHOG effector 1
chr17_+_4833331 1.35 ENST00000355280.11
ENST00000347992.11
misshapen like kinase 1
chr12_+_64404338 1.35 ENST00000332707.10
exportin for tRNA
chr7_+_144355288 1.28 ENST00000498580.5
ENST00000056217.10
Rho guanine nucleotide exchange factor 5
chr18_+_57435366 1.27 ENST00000491143.3
one cut homeobox 2
chr9_+_37422673 1.26 ENST00000318158.11
ENST00000607784.1
glyoxylate and hydroxypyruvate reductase
chr6_-_108074703 1.19 ENST00000193322.8
osteoclastogenesis associated transmembrane protein 1
chr7_+_107580215 1.17 ENST00000465919.5
ENST00000005259.9
ENST00000445771.6
ENST00000479917.5
ENST00000421217.5
ENST00000457837.5
B cell receptor associated protein 29
chr2_+_147845020 1.15 ENST00000241416.12
activin A receptor type 2A
chr12_+_12717359 1.15 ENST00000614874.2
ENST00000228872.9
cyclin dependent kinase inhibitor 1B
chr2_+_108719473 1.14 ENST00000283195.11
RAN binding protein 2
chrX_-_78139612 1.12 ENST00000341864.6
TATA-box binding protein associated factor 9b
chr12_+_50085325 1.08 ENST00000551966.5
ENST00000550477.5
ENST00000394963.9
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr1_+_99969979 1.06 ENST00000427993.7
ENST00000533028.8
ENST00000639221.1
ENST00000638336.1
ENST00000639807.1
ENST00000640715.1
ENST00000465289.6
ENST00000639994.1
ENST00000638988.1
ENST00000640732.1
ENST00000640600.1
ENST00000638338.1
ENST00000638792.1
ENST00000639037.1
solute carrier family 35 member A3
novel protein
chr2_+_159712457 1.04 ENST00000539065.5
ENST00000259050.8
ENST00000409175.6
ENST00000421037.1
membrane associated ring-CH-type finger 7
chr3_-_125375249 1.01 ENST00000484491.5
ENST00000492394.5
ENST00000471196.1
ENST00000468369.5
ENST00000485866.5
ENST00000360647.9
zinc finger protein 148
chr5_+_133051983 1.01 ENST00000304858.7
ENST00000617074.4
ENST00000615899.1
heat shock protein family A (Hsp70) member 4
chr17_-_64506281 1.01 ENST00000225792.10
ENST00000585060.5
DEAD-box helicase 5
chr20_-_25585517 0.99 ENST00000422516.5
ENST00000278886.11
ninein like
chr8_-_101205561 0.98 ENST00000519744.5
ENST00000311212.9
ENST00000521272.5
ENST00000519882.5
zinc finger protein 706
chr16_+_31033513 0.97 ENST00000313843.8
syntaxin 4
chr6_+_10555787 0.96 ENST00000316170.9
glucosaminyl (N-acetyl) transferase 2 (I blood group)
chr20_-_49568101 0.95 ENST00000244043.5
prostaglandin I2 synthase
chr8_-_8893548 0.93 ENST00000276282.7
malignant fibrous histiocytoma amplified sequence 1
chr15_-_75579248 0.91 ENST00000306726.6
ENST00000618819.5
protein tyrosine phosphatase non-receptor type 9
chr3_-_115071333 0.85 ENST00000462705.5
zinc finger and BTB domain containing 20
chr8_+_94823210 0.85 ENST00000521860.5
ENST00000523731.6
ENST00000519457.5
ENST00000519053.5
integrator complex subunit 8
chr13_-_23375431 0.85 ENST00000683270.1
ENST00000684163.1
ENST00000402364.1
ENST00000683367.1
sacsin molecular chaperone
chr15_-_63381835 0.84 ENST00000344366.7
ENST00000178638.8
ENST00000422263.2
carbonic anhydrase 12
chr14_+_102922639 0.84 ENST00000299155.10
amnion associated transmembrane protein
chr12_+_50400809 0.80 ENST00000293618.12
ENST00000429001.7
ENST00000398473.7
ENST00000548174.5
ENST00000548697.5
ENST00000548993.5
ENST00000614335.4
ENST00000522085.5
ENST00000615080.4
ENST00000518444.5
ENST00000551886.5
ENST00000523389.5
ENST00000518561.5
ENST00000347328.9
ENST00000550260.1
La ribonucleoprotein 4
chr1_+_88684222 0.78 ENST00000316005.11
ENST00000370521.8
protein kinase N2
chr5_-_177351522 0.77 ENST00000513877.1
ENST00000515209.5
ENST00000514458.5
ENST00000502560.5
ENST00000303127.12
lectin, mannose binding 2
chr22_-_45977154 0.77 ENST00000339464.9
Wnt family member 7B
chr21_-_33588624 0.77 ENST00000437395.5
ENST00000453626.5
ENST00000303113.10
ENST00000303071.10
ENST00000432378.5
DNA replication fork stabilization factor DONSON
chr9_+_74497308 0.76 ENST00000376896.8
RAR related orphan receptor B
chr20_-_14337602 0.73 ENST00000378053.3
ENST00000341420.5
fibronectin leucine rich transmembrane protein 3
chr7_-_140062841 0.71 ENST00000263549.8
poly(ADP-ribose) polymerase family member 12
chr10_+_73744346 0.69 ENST00000345254.9
ENST00000339365.2
SEC24 homolog C, COPII coat complex component
chr2_+_190408324 0.68 ENST00000417958.5
ENST00000432036.5
ENST00000392328.6
major facilitator superfamily domain containing 6
chr6_+_20401864 0.67 ENST00000346618.8
ENST00000613242.4
E2F transcription factor 3
chr3_+_38453832 0.67 ENST00000352511.5
activin A receptor type 2B
chr11_-_77820706 0.66 ENST00000440064.2
ENST00000528095.5
ENST00000308488.11
remodeling and spacing factor 1
chr13_-_74133892 0.65 ENST00000377669.7
Kruppel like factor 12
chr2_+_100820102 0.61 ENST00000335681.10
neuronal PAS domain protein 2
chr9_-_104928139 0.59 ENST00000423487.6
ENST00000374733.1
ENST00000374736.8
ENST00000678995.1
ATP binding cassette subfamily A member 1
chr17_-_5486157 0.58 ENST00000572834.5
ENST00000158771.9
ENST00000570848.5
ENST00000571971.1
derlin 2
chr16_+_71895493 0.58 ENST00000606369.5
ENST00000537613.5
ENST00000424485.6
ENST00000378799.11
ENST00000329908.12
ENST00000538850.5
ENST00000541918.5
ENST00000534994.5
ENST00000378798.9
ENST00000539186.5
IST1 factor associated with ESCRT-III
chr12_-_8949628 0.57 ENST00000000412.8
ENST00000543845.1
ENST00000544245.1
ENST00000536844.5
mannose-6-phosphate receptor, cation dependent
chr9_+_34990250 0.56 ENST00000454002.6
ENST00000545841.5
DnaJ heat shock protein family (Hsp40) member B5
chr16_-_30787169 0.56 ENST00000262525.6
zinc finger protein 629
chr9_-_36400260 0.52 ENST00000259605.11
ENST00000353739.8
ENST00000611646.4
ring finger protein 38
chr15_+_64387828 0.50 ENST00000261884.8
thyroid hormone receptor interactor 4
chr17_+_782340 0.50 ENST00000304478.9
mitochondrial rRNA methyltransferase 3
chr19_+_44846175 0.49 ENST00000252485.8
ENST00000252483.10
nectin cell adhesion molecule 2
chr21_-_26967057 0.48 ENST00000284987.6
ADAM metallopeptidase with thrombospondin type 1 motif 5
chr17_+_59619885 0.46 ENST00000269122.8
ENST00000580081.1
ENST00000579456.5
clathrin heavy chain
chr1_-_37034492 0.45 ENST00000373091.8
glutamate ionotropic receptor kainate type subunit 3
chr2_-_101151253 0.45 ENST00000376840.8
ENST00000409318.2
TBC1 domain family member 8
chr17_-_58007217 0.44 ENST00000258962.5
ENST00000582730.6
ENST00000584773.5
ENST00000585096.1
serine and arginine rich splicing factor 1
chr1_+_3069160 0.43 ENST00000511072.5
PR/SET domain 16
chr2_+_70258088 0.38 ENST00000433351.7
ENST00000264441.9
prenylcysteine oxidase 1
chr17_+_47896150 0.37 ENST00000642065.1
ENST00000613139.1
ENST00000637314.1
ENST00000637943.1
ENST00000376741.5
ENST00000635868.1
Sp2 transcription factor
chr7_-_27156646 0.34 ENST00000242159.5
homeobox A7
chr3_-_136752361 0.31 ENST00000480733.1
ENST00000629124.2
ENST00000383202.7
ENST00000236698.9
ENST00000434713.6
stromal antigen 1
chr16_-_71808803 0.30 ENST00000563104.5
ENST00000569975.5
ENST00000565412.5
ENST00000567583.1
ENST00000299980.9
adaptor related protein complex 1 subunit gamma 1
chr19_+_39125769 0.29 ENST00000602004.1
ENST00000599470.5
ENST00000321944.8
ENST00000593480.5
ENST00000358301.7
ENST00000593690.5
ENST00000599386.5
p21 (RAC1) activated kinase 4
chr7_+_77798750 0.28 ENST00000416283.6
ENST00000422959.6
ENST00000307305.12
ENST00000424760.5
putative homeodomain transcription factor 2
chr1_-_208244375 0.26 ENST00000367033.4
plexin A2
chr1_-_89065200 0.25 ENST00000370473.5
guanylate binding protein 1
chr3_+_99638475 0.23 ENST00000452013.5
ENST00000261037.7
ENST00000652472.1
ENST00000273342.8
ENST00000621757.1
collagen type VIII alpha 1 chain
chr18_-_28177102 0.23 ENST00000413878.2
ENST00000269141.8
cadherin 2
chr4_-_23890035 0.21 ENST00000507380.1
ENST00000264867.7
PPARG coactivator 1 alpha
chr2_-_36966503 0.20 ENST00000263918.9
striatin
chr12_-_122422544 0.19 ENST00000358808.6
ENST00000361654.8
ENST00000539080.1
ENST00000537178.5
CAP-Gly domain containing linker protein 1
chr12_-_66678934 0.18 ENST00000545666.5
ENST00000398016.7
ENST00000359742.9
ENST00000538211.5
glutamate receptor interacting protein 1
chr11_-_34357994 0.17 ENST00000435224.3
ankyrin repeat and BTB domain containing 2
chr15_+_85380565 0.17 ENST00000559362.5
ENST00000394518.7
A-kinase anchoring protein 13
chr3_-_120094436 0.15 ENST00000264235.13
ENST00000677034.1
glycogen synthase kinase 3 beta
chr2_+_44168866 0.15 ENST00000282412.9
ENST00000409432.7
ENST00000378551.6
ENST00000345249.8
protein phosphatase, Mg2+/Mn2+ dependent 1B
chr10_+_96043394 0.14 ENST00000403870.7
ENST00000265992.9
ENST00000465148.3
cyclin J
chr10_+_100535927 0.11 ENST00000299163.7
hypoxia inducible factor 1 subunit alpha inhibitor
chr11_+_120336357 0.09 ENST00000397843.7
Rho guanine nucleotide exchange factor 12
chr3_-_52679713 0.08 ENST00000296302.11
ENST00000356770.8
ENST00000337303.8
ENST00000409057.5
ENST00000410007.5
ENST00000409114.7
ENST00000409767.5
ENST00000423351.5
polybromo 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.3 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
2.2 6.6 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
2.2 8.8 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
2.1 6.4 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
1.9 7.8 GO:1903891 regulation of ATF6-mediated unfolded protein response(GO:1903891)
1.7 8.5 GO:0035910 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
1.6 4.9 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
1.6 9.7 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
1.4 4.2 GO:0009447 putrescine catabolic process(GO:0009447)
1.1 3.4 GO:0048250 mitochondrial iron ion transport(GO:0048250)
1.0 3.9 GO:0061443 ciliary body morphogenesis(GO:0061073) endocardial cushion cell differentiation(GO:0061443)
1.0 2.9 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.9 2.6 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.8 11.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.7 2.8 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.7 2.1 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.7 12.7 GO:0070831 basement membrane assembly(GO:0070831)
0.7 10.6 GO:0039532 negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.6 1.7 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.6 2.3 GO:2000327 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.5 1.6 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.5 1.5 GO:0032289 central nervous system myelin formation(GO:0032289)
0.5 3.1 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.5 2.0 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.5 2.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.5 1.4 GO:0071922 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.4 1.7 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.4 1.6 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.4 2.9 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.4 5.7 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.4 3.5 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.4 2.3 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.4 3.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.4 6.7 GO:0034384 high-density lipoprotein particle clearance(GO:0034384)
0.4 2.9 GO:0007256 activation of JNKK activity(GO:0007256)
0.4 5.7 GO:0045793 positive regulation of cell size(GO:0045793)
0.4 1.8 GO:0070295 renal water absorption(GO:0070295) positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.3 5.6 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.3 3.5 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.3 1.7 GO:0031291 Ran protein signal transduction(GO:0031291)
0.3 4.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.3 1.0 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.3 1.3 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.3 1.5 GO:0016240 autophagosome docking(GO:0016240)
0.3 2.1 GO:0001705 ectoderm formation(GO:0001705) ectodermal cell fate commitment(GO:0001712)
0.3 0.6 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.3 1.7 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing by siRNA(GO:0090625) mRNA cleavage involved in gene silencing(GO:0098795)
0.3 2.4 GO:0060613 fat pad development(GO:0060613)
0.2 0.5 GO:1900125 regulation of hyaluronan biosynthetic process(GO:1900125)
0.2 8.0 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.2 2.7 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.2 4.4 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.2 1.7 GO:0071651 mature ribosome assembly(GO:0042256) positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.2 4.4 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.2 1.9 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.2 1.8 GO:0015693 magnesium ion transport(GO:0015693)
0.2 3.7 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.2 1.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 1.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.2 0.8 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.2 1.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.2 1.8 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.2 1.6 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.2 2.8 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 1.7 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.2 1.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.2 4.5 GO:2000637 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.2 12.8 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.2 1.1 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 0.7 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 0.6 GO:0009838 abscission(GO:0009838)
0.1 3.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 3.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 2.1 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.1 3.0 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 1.0 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 1.7 GO:0045008 depyrimidination(GO:0045008)
0.1 0.4 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.1 0.8 GO:0035881 amacrine cell differentiation(GO:0035881)
0.1 2.8 GO:0007172 signal complex assembly(GO:0007172)
0.1 0.5 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.1 3.5 GO:1903432 regulation of TORC1 signaling(GO:1903432)
0.1 0.8 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 3.7 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 2.3 GO:0006907 pinocytosis(GO:0006907)
0.1 1.0 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.1 1.6 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.1 2.3 GO:0033622 integrin activation(GO:0033622)
0.1 0.2 GO:2000182 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637) regulation of progesterone biosynthetic process(GO:2000182)
0.1 0.3 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.6 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.7 GO:0016584 nucleosome positioning(GO:0016584)
0.1 1.7 GO:0071670 smooth muscle cell chemotaxis(GO:0071670)
0.1 4.1 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 3.1 GO:0032094 response to food(GO:0032094)
0.1 4.5 GO:0048009 insulin-like growth factor receptor signaling pathway(GO:0048009)
0.1 0.7 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.2 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 2.8 GO:2000758 positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.1 0.5 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.1 3.4 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.1 6.2 GO:0032465 regulation of cytokinesis(GO:0032465)
0.1 0.6 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 3.6 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.1 1.0 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 1.8 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.1 3.1 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.1 0.2 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 5.7 GO:0006446 regulation of translational initiation(GO:0006446)
0.1 0.5 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 1.1 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.1 2.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 1.5 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.1 0.4 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.1 1.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 2.9 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 0.3 GO:0060174 limb bud formation(GO:0060174)
0.1 0.2 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.6 GO:0051775 response to redox state(GO:0051775)
0.0 3.0 GO:0031102 neuron projection regeneration(GO:0031102)
0.0 0.3 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.7 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 2.4 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.1 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.5 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.9 GO:0016180 snRNA processing(GO:0016180)
0.0 2.4 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.2 GO:0060019 radial glial cell differentiation(GO:0060019)
0.0 4.0 GO:0048704 embryonic skeletal system morphogenesis(GO:0048704)
0.0 1.8 GO:0030042 actin filament depolymerization(GO:0030042)
0.0 0.9 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.0 GO:0060601 lateral sprouting from an epithelium(GO:0060601)
0.0 0.2 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 2.0 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.0 2.3 GO:0070268 cornification(GO:0070268)
0.0 1.0 GO:0021762 substantia nigra development(GO:0021762)
0.0 0.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.5 GO:1901998 toxin transport(GO:1901998)
0.0 0.9 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 1.5 GO:0021987 cerebral cortex development(GO:0021987)
0.0 1.3 GO:0007588 excretion(GO:0007588)
0.0 0.8 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.0 3.2 GO:0006457 protein folding(GO:0006457)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 12.7 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
2.0 8.0 GO:0071942 XPC complex(GO:0071942)
1.3 6.6 GO:0097513 actomyosin contractile ring(GO:0005826) myosin II filament(GO:0097513)
1.2 3.7 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.8 7.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.7 1.5 GO:1903349 omegasome membrane(GO:1903349)
0.7 5.7 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.6 2.5 GO:0097422 tubular endosome(GO:0097422)
0.6 10.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.6 3.5 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.5 7.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.4 4.9 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.4 2.9 GO:0031415 NatA complex(GO:0031415)
0.4 3.5 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.4 1.1 GO:1990723 cytoplasmic periphery of the nuclear pore complex(GO:1990723)
0.3 1.4 GO:0005797 Golgi medial cisterna(GO:0005797)
0.3 7.0 GO:0005685 U1 snRNP(GO:0005685)
0.3 8.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 2.9 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.2 1.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.2 2.7 GO:0090543 Flemming body(GO:0090543)
0.2 2.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 1.4 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2 1.7 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.2 9.7 GO:1904115 axon cytoplasm(GO:1904115)
0.2 2.8 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.9 GO:0031209 SCAR complex(GO:0031209)
0.1 6.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 2.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 1.4 GO:0008278 cohesin complex(GO:0008278)
0.1 2.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 2.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 4.5 GO:0090544 BAF-type complex(GO:0090544)
0.1 0.6 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 1.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 6.9 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 10.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 6.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.8 GO:0070852 cell body fiber(GO:0070852)
0.1 1.1 GO:0000124 SAGA complex(GO:0000124)
0.1 0.9 GO:0032039 integrator complex(GO:0032039)
0.1 2.3 GO:0030057 desmosome(GO:0030057)
0.1 7.5 GO:0005604 basement membrane(GO:0005604)
0.1 3.5 GO:0005844 polysome(GO:0005844)
0.1 1.0 GO:0032059 bleb(GO:0032059)
0.1 1.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 5.8 GO:0005811 lipid particle(GO:0005811)
0.1 2.5 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 0.7 GO:0031010 ISWI-type complex(GO:0031010)
0.1 6.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 1.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 3.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.5 GO:0071439 clathrin complex(GO:0071439)
0.0 1.0 GO:0071141 SMAD protein complex(GO:0071141)
0.0 2.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 4.7 GO:0005643 nuclear pore(GO:0005643)
0.0 0.5 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 2.8 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.6 GO:0030904 retromer complex(GO:0030904)
0.0 0.7 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 1.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 1.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 2.4 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 2.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.4 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 3.8 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 2.6 GO:0030496 midbody(GO:0030496)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 2.8 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.0 0.2 GO:0097440 apical dendrite(GO:0097440)
0.0 0.8 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.5 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.3 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
1.5 4.5 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
1.4 4.3 GO:0005055 laminin receptor activity(GO:0005055)
1.1 4.4 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.7 2.9 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.7 2.8 GO:0002060 purine nucleobase binding(GO:0002060)
0.7 2.0 GO:0051717 phosphohistidine phosphatase activity(GO:0008969) bisphosphoglycerate phosphatase activity(GO:0034416) inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717)
0.7 2.7 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.6 1.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.5 2.6 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.5 3.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.5 1.8 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.4 2.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.4 1.7 GO:0043273 CTPase activity(GO:0043273)
0.4 2.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.4 3.5 GO:0033592 RNA strand annealing activity(GO:0033592)
0.3 7.8 GO:0051787 misfolded protein binding(GO:0051787)
0.3 1.6 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.3 1.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.3 6.6 GO:0043495 protein anchor(GO:0043495)
0.3 2.9 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.3 3.4 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.3 2.3 GO:0030274 LIM domain binding(GO:0030274)
0.2 1.0 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.2 12.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 1.8 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.2 2.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 6.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.2 0.6 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.2 4.0 GO:0005112 Notch binding(GO:0005112)
0.2 1.7 GO:0016015 morphogen activity(GO:0016015)
0.2 4.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 1.3 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.2 2.5 GO:0034452 dynactin binding(GO:0034452)
0.2 1.7 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.2 1.0 GO:0035500 MH2 domain binding(GO:0035500)
0.2 0.5 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.2 3.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 5.4 GO:0070064 proline-rich region binding(GO:0070064)
0.2 4.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 8.0 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 1.2 GO:0098821 BMP receptor activity(GO:0098821)
0.1 1.0 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 2.4 GO:0097016 L27 domain binding(GO:0097016)
0.1 1.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 13.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.3 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 3.6 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.1 2.1 GO:0031996 thioesterase binding(GO:0031996)
0.1 5.0 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 2.8 GO:0017166 vinculin binding(GO:0017166)
0.1 1.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 3.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 2.6 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 7.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 2.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 7.2 GO:0019003 GDP binding(GO:0019003)
0.1 5.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 1.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1 3.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 1.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 4.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.9 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 6.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 0.5 GO:0098988 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.1 1.8 GO:0071949 FAD binding(GO:0071949)
0.1 6.9 GO:0030165 PDZ domain binding(GO:0030165)
0.1 6.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.3 GO:0005537 mannose binding(GO:0005537)
0.1 6.7 GO:0008565 protein transporter activity(GO:0008565)
0.1 4.2 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.1 0.4 GO:0044547 DNA topoisomerase binding(GO:0044547) RS domain binding(GO:0050733)
0.1 1.1 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.4 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.1 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 2.3 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.8 GO:0070628 proteasome binding(GO:0070628)
0.0 3.4 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 1.4 GO:0000049 tRNA binding(GO:0000049)
0.0 0.8 GO:0004697 protein kinase C activity(GO:0004697)
0.0 1.4 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 8.5 GO:0030246 carbohydrate binding(GO:0030246)
0.0 1.2 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.8 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 2.6 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 1.0 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 0.6 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.5 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 1.2 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.1 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 7.0 GO:0045296 cadherin binding(GO:0045296)
0.0 0.4 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 12.7 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.4 20.0 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.2 7.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 7.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 6.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 1.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 2.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 2.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 7.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.1 2.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.1 3.0 PID REELIN PATHWAY Reelin signaling pathway
0.1 3.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 1.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 2.3 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 1.8 PID ALK1 PATHWAY ALK1 signaling events
0.1 2.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.9 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 7.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.6 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 2.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.0 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.6 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 6.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.8 PID RHOA PATHWAY RhoA signaling pathway
0.0 1.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.1 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.1 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.0 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.4 3.9 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.3 10.3 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.3 9.7 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.2 8.0 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.2 4.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 8.2 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 2.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 1.7 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.2 7.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 2.6 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 3.4 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 1.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 2.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 11.6 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 7.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 1.8 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 2.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 1.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 3.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 5.1 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 0.8 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 1.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 3.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.1 2.1 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 2.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 0.7 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 1.0 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 1.3 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.5 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 1.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 5.7 REACTOME TRANSLATION Genes involved in Translation
0.0 2.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 4.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.5 REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING Genes involved in Activation of Kainate Receptors upon glutamate binding
0.0 1.0 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production