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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for CCCUGAG
Z-value: 7.12
Motif logo
miRNA associated with seed CCCUGAG
| Name | miRBASE accession |
|---|---|
|
hsa-miR-125a-5p
|
MIMAT0000443 |
|
hsa-miR-125b-5p
|
MIMAT0000423 |
|
hsa-miR-4319
|
MIMAT0016870 |
Activity profile of CCCUGAG motif
Sorted Z-values of CCCUGAG motif
Network of associatons between targets according to the STRING database.
First level regulatory network of CCCUGAG
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrX_+_65488735 | 40.53 |
ENST00000338957.4
|
ZC3H12B
|
zinc finger CCCH-type containing 12B |
| chr15_+_31326807 | 30.92 |
ENST00000307145.4
|
KLF13
|
Kruppel like factor 13 |
| chr9_-_113340248 | 24.55 |
ENST00000341761.8
ENST00000374195.7 ENST00000374193.9 |
WDR31
|
WD repeat domain 31 |
| chr1_+_77779618 | 23.10 |
ENST00000370791.7
ENST00000443751.3 ENST00000645756.1 ENST00000643390.1 ENST00000642959.1 |
MIGA1
|
mitoguardin 1 |
| chr22_-_39152622 | 22.89 |
ENST00000216133.10
|
CBX7
|
chromobox 7 |
| chr6_+_11537738 | 21.66 |
ENST00000379426.2
|
TMEM170B
|
transmembrane protein 170B |
| chr19_+_7903843 | 21.20 |
ENST00000397981.7
ENST00000397979.4 ENST00000397983.7 |
MAP2K7
|
mitogen-activated protein kinase kinase 7 |
| chr4_-_2262082 | 20.51 |
ENST00000337190.7
|
MXD4
|
MAX dimerization protein 4 |
| chr15_+_74541200 | 20.31 |
ENST00000622429.1
ENST00000346246.10 |
ARID3B
|
AT-rich interaction domain 3B |
| chr3_-_57693045 | 20.21 |
ENST00000311128.10
|
DENND6A
|
DENN domain containing 6A |
| chr2_-_206086057 | 19.65 |
ENST00000403263.6
|
INO80D
|
INO80 complex subunit D |
| chr11_-_22829793 | 19.14 |
ENST00000354193.5
|
SVIP
|
small VCP interacting protein |
| chr12_+_51424802 | 18.31 |
ENST00000453097.7
|
SLC4A8
|
solute carrier family 4 member 8 |
| chr8_-_65842051 | 18.07 |
ENST00000401827.8
|
PDE7A
|
phosphodiesterase 7A |
| chr17_+_18315273 | 17.82 |
ENST00000406438.5
|
SMCR8
|
SMCR8-C9orf72 complex subunit |
| chr9_-_120714457 | 17.36 |
ENST00000373930.4
|
MEGF9
|
multiple EGF like domains 9 |
| chr17_-_63700100 | 17.29 |
ENST00000578993.5
ENST00000259006.8 ENST00000583211.5 |
LIMD2
|
LIM domain containing 2 |
| chr2_+_61065863 | 16.89 |
ENST00000402291.6
|
KIAA1841
|
KIAA1841 |
| chr3_+_15427551 | 16.86 |
ENST00000396842.7
|
EAF1
|
ELL associated factor 1 |
| chr8_+_38176802 | 16.62 |
ENST00000287322.5
|
BAG4
|
BAG cochaperone 4 |
| chr22_+_41381923 | 16.53 |
ENST00000266304.9
|
TEF
|
TEF transcription factor, PAR bZIP family member |
| chr4_+_7043315 | 16.49 |
ENST00000310074.8
ENST00000512388.1 |
TADA2B
|
transcriptional adaptor 2B |
| chr17_-_78717018 | 15.58 |
ENST00000585509.5
|
CYTH1
|
cytohesin 1 |
| chr6_+_106098933 | 14.74 |
ENST00000369089.3
|
PRDM1
|
PR/SET domain 1 |
| chr10_+_119207560 | 14.24 |
ENST00000392870.3
|
GRK5
|
G protein-coupled receptor kinase 5 |
| chr11_-_62727444 | 14.24 |
ENST00000301785.7
|
HNRNPUL2
|
heterogeneous nuclear ribonucleoprotein U like 2 |
| chr1_-_207051202 | 14.19 |
ENST00000315927.9
|
YOD1
|
YOD1 deubiquitinase |
| chr16_+_1612337 | 14.01 |
ENST00000674071.1
ENST00000397412.8 |
CRAMP1
|
cramped chromatin regulator homolog 1 |
| chr2_-_201071579 | 14.01 |
ENST00000453765.5
ENST00000452799.5 ENST00000446678.5 ENST00000418596.7 ENST00000681958.1 |
FAM126B
|
family with sequence similarity 126 member B |
| chr19_-_18522051 | 13.99 |
ENST00000262809.9
|
ELL
|
elongation factor for RNA polymerase II |
| chr11_+_33257265 | 13.97 |
ENST00000303296.9
ENST00000379016.7 |
HIPK3
|
homeodomain interacting protein kinase 3 |
| chr2_+_73984902 | 13.89 |
ENST00000409262.8
|
TET3
|
tet methylcytosine dioxygenase 3 |
| chr1_+_203305510 | 13.72 |
ENST00000290551.5
|
BTG2
|
BTG anti-proliferation factor 2 |
| chr16_-_28925172 | 13.55 |
ENST00000544477.5
ENST00000357573.10 ENST00000358201.9 |
RABEP2
|
rabaptin, RAB GTPase binding effector protein 2 |
| chr15_+_81196871 | 13.52 |
ENST00000559383.5
ENST00000394660.6 ENST00000683961.1 |
IL16
|
interleukin 16 |
| chr6_+_391743 | 13.49 |
ENST00000380956.9
|
IRF4
|
interferon regulatory factor 4 |
| chr15_-_72117712 | 13.39 |
ENST00000444904.5
ENST00000564571.5 |
MYO9A
|
myosin IXA |
| chr3_+_183635605 | 13.08 |
ENST00000493074.1
ENST00000437402.5 ENST00000454495.6 ENST00000473045.5 ENST00000468101.5 ENST00000427201.2 ENST00000482138.1 ENST00000454652.6 ENST00000242810.11 |
KLHL24
|
kelch like family member 24 |
| chr9_-_124771304 | 12.69 |
ENST00000416460.6
ENST00000487099.7 |
NR6A1
|
nuclear receptor subfamily 6 group A member 1 |
| chr12_-_120369156 | 12.69 |
ENST00000257552.7
|
MSI1
|
musashi RNA binding protein 1 |
| chr16_+_4847431 | 12.67 |
ENST00000262376.11
|
UBN1
|
ubinuclein 1 |
| chr19_+_18683656 | 12.56 |
ENST00000338797.10
ENST00000321949.13 |
CRTC1
|
CREB regulated transcription coactivator 1 |
| chr4_-_25030922 | 12.53 |
ENST00000382114.9
|
LGI2
|
leucine rich repeat LGI family member 2 |
| chrX_+_111096136 | 12.34 |
ENST00000372007.10
|
PAK3
|
p21 (RAC1) activated kinase 3 |
| chr12_+_11649666 | 12.33 |
ENST00000396373.9
|
ETV6
|
ETS variant transcription factor 6 |
| chr5_-_160312524 | 12.21 |
ENST00000520748.1
ENST00000257536.13 ENST00000393977.7 |
CCNJL
|
cyclin J like |
| chr2_-_9003657 | 12.12 |
ENST00000462696.1
ENST00000305997.8 |
MBOAT2
|
membrane bound O-acyltransferase domain containing 2 |
| chr15_-_89814845 | 11.84 |
ENST00000679248.1
ENST00000300060.7 ENST00000560137.2 |
ANPEP
|
alanyl aminopeptidase, membrane |
| chr3_+_186930518 | 11.78 |
ENST00000169298.8
ENST00000457772.6 ENST00000455441.5 ENST00000427315.5 |
ST6GAL1
|
ST6 beta-galactoside alpha-2,6-sialyltransferase 1 |
| chr22_-_43862480 | 11.68 |
ENST00000330884.9
|
SULT4A1
|
sulfotransferase family 4A member 1 |
| chr1_-_21345475 | 11.24 |
ENST00000415912.6
|
ECE1
|
endothelin converting enzyme 1 |
| chr11_-_128522264 | 11.13 |
ENST00000531611.5
|
ETS1
|
ETS proto-oncogene 1, transcription factor |
| chr3_+_46979659 | 11.05 |
ENST00000450053.8
|
NBEAL2
|
neurobeachin like 2 |
| chrX_-_19970298 | 11.03 |
ENST00000379687.7
ENST00000379682.8 |
BCLAF3
|
BCLAF1 and THRAP3 family member 3 |
| chr17_-_50130121 | 10.95 |
ENST00000330175.9
|
SAMD14
|
sterile alpha motif domain containing 14 |
| chr12_-_42144823 | 10.89 |
ENST00000398675.8
|
GXYLT1
|
glucoside xylosyltransferase 1 |
| chr6_+_137867414 | 10.88 |
ENST00000237289.8
ENST00000433680.1 |
TNFAIP3
|
TNF alpha induced protein 3 |
| chr19_+_40191410 | 10.80 |
ENST00000253055.8
|
MAP3K10
|
mitogen-activated protein kinase kinase kinase 10 |
| chr7_-_140176970 | 10.72 |
ENST00000397560.7
|
KDM7A
|
lysine demethylase 7A |
| chr5_-_176537361 | 10.55 |
ENST00000274811.9
|
RNF44
|
ring finger protein 44 |
| chr1_+_12166978 | 10.39 |
ENST00000376259.7
ENST00000536782.2 |
TNFRSF1B
|
TNF receptor superfamily member 1B |
| chr19_+_4969105 | 10.39 |
ENST00000611640.4
ENST00000159111.9 ENST00000588337.5 ENST00000381759.8 |
KDM4B
|
lysine demethylase 4B |
| chr16_-_2214776 | 10.23 |
ENST00000333503.8
|
PGP
|
phosphoglycolate phosphatase |
| chr1_-_212035513 | 10.15 |
ENST00000366992.7
ENST00000366993.7 ENST00000440600.6 ENST00000366994.8 |
INTS7
|
integrator complex subunit 7 |
| chr9_-_128067310 | 10.14 |
ENST00000373078.5
|
NAIF1
|
nuclear apoptosis inducing factor 1 |
| chr10_+_102918276 | 9.51 |
ENST00000369878.9
ENST00000369875.3 |
CNNM2
|
cyclin and CBS domain divalent metal cation transport mediator 2 |
| chr7_-_143362687 | 9.45 |
ENST00000409578.5
ENST00000443739.7 ENST00000409346.5 |
FAM131B
|
family with sequence similarity 131 member B |
| chr1_-_157138388 | 9.35 |
ENST00000368192.9
|
ETV3
|
ETS variant transcription factor 3 |
| chr16_-_71577082 | 9.34 |
ENST00000355962.5
|
TAT
|
tyrosine aminotransferase |
| chr6_+_138161932 | 9.29 |
ENST00000251691.5
|
ARFGEF3
|
ARFGEF family member 3 |
| chr5_+_56815534 | 9.19 |
ENST00000399503.4
|
MAP3K1
|
mitogen-activated protein kinase kinase kinase 1 |
| chr1_+_47438036 | 9.11 |
ENST00000334793.6
|
FOXD2
|
forkhead box D2 |
| chr14_+_69398683 | 9.01 |
ENST00000556605.5
ENST00000031146.8 ENST00000336643.10 |
SLC39A9
|
solute carrier family 39 member 9 |
| chr6_-_24911029 | 8.97 |
ENST00000259698.9
ENST00000644621.1 ENST00000644411.1 |
RIPOR2
|
RHO family interacting cell polarization regulator 2 |
| chr16_+_27550127 | 8.94 |
ENST00000261588.9
|
KATNIP
|
katanin interacting protein |
| chr15_-_61229297 | 8.92 |
ENST00000335670.11
|
RORA
|
RAR related orphan receptor A |
| chr5_+_96936071 | 8.86 |
ENST00000231368.10
|
LNPEP
|
leucyl and cystinyl aminopeptidase |
| chr11_-_64844620 | 8.67 |
ENST00000342711.6
|
CDC42BPG
|
CDC42 binding protein kinase gamma |
| chr10_+_99329349 | 8.67 |
ENST00000356713.5
|
CNNM1
|
cyclin and CBS domain divalent metal cation transport mediator 1 |
| chr15_-_79090760 | 8.63 |
ENST00000419573.7
ENST00000558480.7 |
RASGRF1
|
Ras protein specific guanine nucleotide releasing factor 1 |
| chr1_+_32108035 | 8.60 |
ENST00000373625.8
|
KPNA6
|
karyopherin subunit alpha 6 |
| chr3_+_50674896 | 8.59 |
ENST00000266037.10
|
DOCK3
|
dedicator of cytokinesis 3 |
| chr12_+_69239560 | 8.58 |
ENST00000435070.7
|
CPSF6
|
cleavage and polyadenylation specific factor 6 |
| chr19_+_19211949 | 8.57 |
ENST00000252575.11
|
NCAN
|
neurocan |
| chr2_-_38377256 | 8.54 |
ENST00000443098.5
ENST00000449130.5 ENST00000651368.1 ENST00000378954.9 ENST00000419554.6 ENST00000451483.1 ENST00000406122.5 |
ATL2
|
atlastin GTPase 2 |
| chr3_-_13420307 | 8.49 |
ENST00000254508.7
|
NUP210
|
nucleoporin 210 |
| chr12_+_13044371 | 8.40 |
ENST00000197268.13
|
FAM234B
|
family with sequence similarity 234 member B |
| chr12_+_4909895 | 8.40 |
ENST00000638821.1
ENST00000382545.5 |
ENSG00000256654.4
KCNA1
|
novel transcript, sense overlapping KCNA1 potassium voltage-gated channel subfamily A member 1 |
| chr15_-_73368951 | 8.38 |
ENST00000261917.4
|
HCN4
|
hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| chr3_+_49554436 | 8.08 |
ENST00000296452.5
|
BSN
|
bassoon presynaptic cytomatrix protein |
| chr11_-_46918522 | 8.00 |
ENST00000378623.6
ENST00000534404.1 |
LRP4
|
LDL receptor related protein 4 |
| chr1_+_169368175 | 8.00 |
ENST00000367808.8
ENST00000426663.1 |
BLZF1
|
basic leucine zipper nuclear factor 1 |
| chr7_+_49773632 | 7.91 |
ENST00000340652.5
|
VWC2
|
von Willebrand factor C domain containing 2 |
| chr1_+_205227889 | 7.91 |
ENST00000358024.8
|
TMCC2
|
transmembrane and coiled-coil domain family 2 |
| chr16_-_75464655 | 7.80 |
ENST00000569276.1
ENST00000357613.8 ENST00000561878.2 ENST00000566980.1 ENST00000567194.5 |
TMEM170A
ENSG00000261717.5
|
transmembrane protein 170A novel TMEM170A-CFDP1 readthrough protein |
| chr6_-_100464912 | 7.75 |
ENST00000369208.8
|
SIM1
|
SIM bHLH transcription factor 1 |
| chr8_-_63086031 | 7.72 |
ENST00000260116.5
|
TTPA
|
alpha tocopherol transfer protein |
| chr8_-_66667138 | 7.71 |
ENST00000310421.5
|
VCPIP1
|
valosin containing protein interacting protein 1 |
| chr12_-_56333693 | 7.71 |
ENST00000425394.7
ENST00000548043.5 |
PAN2
|
poly(A) specific ribonuclease subunit PAN2 |
| chr10_-_15719885 | 7.70 |
ENST00000378076.4
|
ITGA8
|
integrin subunit alpha 8 |
| chr11_-_118176576 | 7.68 |
ENST00000278947.6
|
SCN2B
|
sodium voltage-gated channel beta subunit 2 |
| chr4_+_110476133 | 7.64 |
ENST00000265162.10
|
ENPEP
|
glutamyl aminopeptidase |
| chr3_+_37452121 | 7.52 |
ENST00000264741.10
|
ITGA9
|
integrin subunit alpha 9 |
| chr2_+_17878637 | 7.52 |
ENST00000304101.9
|
KCNS3
|
potassium voltage-gated channel modifier subfamily S member 3 |
| chr4_+_71339014 | 7.48 |
ENST00000340595.4
|
SLC4A4
|
solute carrier family 4 member 4 |
| chr1_+_182789765 | 7.44 |
ENST00000367555.5
ENST00000367553.6 |
NPL
|
N-acetylneuraminate pyruvate lyase |
| chr12_+_56007484 | 7.38 |
ENST00000262032.9
|
IKZF4
|
IKAROS family zinc finger 4 |
| chr7_+_143288215 | 7.33 |
ENST00000619992.4
ENST00000310447.10 |
CASP2
|
caspase 2 |
| chr9_-_19786928 | 7.31 |
ENST00000341998.6
ENST00000286344.3 |
SLC24A2
|
solute carrier family 24 member 2 |
| chr18_+_33578213 | 7.30 |
ENST00000681521.1
ENST00000269197.12 |
ASXL3
|
ASXL transcriptional regulator 3 |
| chr22_+_21417357 | 7.27 |
ENST00000407464.7
|
HIC2
|
HIC ZBTB transcriptional repressor 2 |
| chr20_+_57391388 | 7.05 |
ENST00000356208.10
ENST00000440234.6 |
RBM38
|
RNA binding motif protein 38 |
| chr19_+_45093140 | 7.05 |
ENST00000544069.2
ENST00000221462.9 |
PPP1R37
|
protein phosphatase 1 regulatory subunit 37 |
| chr1_-_35557378 | 7.05 |
ENST00000325722.8
ENST00000469892.5 |
KIAA0319L
|
KIAA0319 like |
| chr1_-_156282799 | 7.04 |
ENST00000361813.5
|
SMG5
|
SMG5 nonsense mediated mRNA decay factor |
| chr11_+_94543894 | 7.01 |
ENST00000358752.4
|
FUT4
|
fucosyltransferase 4 |
| chr17_+_44758958 | 7.01 |
ENST00000200557.11
|
ADAM11
|
ADAM metallopeptidase domain 11 |
| chr18_+_34978244 | 6.98 |
ENST00000436190.6
|
MAPRE2
|
microtubule associated protein RP/EB family member 2 |
| chr10_+_96832252 | 6.90 |
ENST00000676187.1
ENST00000675687.1 ENST00000676123.1 ENST00000675471.1 ENST00000371103.8 ENST00000421806.4 ENST00000675250.1 ENST00000540664.6 ENST00000676414.1 |
LCOR
|
ligand dependent nuclear receptor corepressor |
| chr8_-_73878816 | 6.90 |
ENST00000602593.6
ENST00000651945.1 ENST00000419880.7 ENST00000517608.5 ENST00000650817.1 |
UBE2W
|
ubiquitin conjugating enzyme E2 W |
| chr13_-_72781871 | 6.87 |
ENST00000377767.9
ENST00000377780.8 |
DIS3
|
DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease |
| chr11_-_78188588 | 6.75 |
ENST00000526208.5
ENST00000529350.1 ENST00000530018.5 ENST00000528776.1 ENST00000340067.4 |
KCTD21
|
potassium channel tetramerization domain containing 21 |
| chr14_+_73644875 | 6.70 |
ENST00000554113.5
ENST00000553645.7 ENST00000555631.6 ENST00000311089.7 ENST00000555919.7 ENST00000554339.5 ENST00000554871.5 |
DNAL1
|
dynein axonemal light chain 1 |
| chr5_-_100903252 | 6.70 |
ENST00000231461.10
|
ST8SIA4
|
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 |
| chr11_-_119381629 | 6.68 |
ENST00000260187.7
ENST00000455332.6 |
USP2
|
ubiquitin specific peptidase 2 |
| chr19_-_19643597 | 6.62 |
ENST00000587205.1
ENST00000203556.9 |
GMIP
|
GEM interacting protein |
| chr1_-_200410052 | 6.54 |
ENST00000294740.3
|
ZNF281
|
zinc finger protein 281 |
| chr9_+_35538619 | 6.51 |
ENST00000455600.1
|
RUSC2
|
RUN and SH3 domain containing 2 |
| chr14_-_92106607 | 6.50 |
ENST00000340660.10
ENST00000393287.9 ENST00000429774.6 ENST00000545170.5 ENST00000620536.4 ENST00000621269.4 |
ATXN3
|
ataxin 3 |
| chr1_-_109397888 | 6.37 |
ENST00000256637.8
|
SORT1
|
sortilin 1 |
| chr22_-_50261272 | 6.34 |
ENST00000395780.5
|
MAPK12
|
mitogen-activated protein kinase 12 |
| chr14_+_70907450 | 6.31 |
ENST00000304743.7
|
PCNX1
|
pecanex 1 |
| chr2_-_102736819 | 6.27 |
ENST00000258436.10
|
MFSD9
|
major facilitator superfamily domain containing 9 |
| chr1_+_26529745 | 6.25 |
ENST00000374168.7
ENST00000374166.8 |
RPS6KA1
|
ribosomal protein S6 kinase A1 |
| chr10_+_72215981 | 6.21 |
ENST00000615507.4
ENST00000621663.4 ENST00000299381.5 |
ANAPC16
|
anaphase promoting complex subunit 16 |
| chr2_-_212538766 | 6.19 |
ENST00000342788.9
|
ERBB4
|
erb-b2 receptor tyrosine kinase 4 |
| chr9_-_35650902 | 6.18 |
ENST00000259608.8
ENST00000618781.1 |
SIT1
|
signaling threshold regulating transmembrane adaptor 1 |
| chr1_-_150579530 | 6.17 |
ENST00000307940.3
ENST00000678610.1 ENST00000678770.1 ENST00000369026.3 |
MCL1
|
MCL1 apoptosis regulator, BCL2 family member |
| chr9_-_92670124 | 6.13 |
ENST00000287996.8
|
IPPK
|
inositol-pentakisphosphate 2-kinase |
| chr14_+_56118404 | 6.13 |
ENST00000267460.9
|
PELI2
|
pellino E3 ubiquitin protein ligase family member 2 |
| chr3_+_5187697 | 6.09 |
ENST00000256497.9
|
EDEM1
|
ER degradation enhancing alpha-mannosidase like protein 1 |
| chr16_-_19718175 | 6.07 |
ENST00000219837.12
|
KNOP1
|
lysine rich nucleolar protein 1 |
| chr17_-_39197652 | 6.05 |
ENST00000394303.8
|
CACNB1
|
calcium voltage-gated channel auxiliary subunit beta 1 |
| chr11_-_117232033 | 6.02 |
ENST00000524507.6
ENST00000320934.8 ENST00000532301.5 ENST00000676339.1 ENST00000540028.5 |
PCSK7
|
proprotein convertase subtilisin/kexin type 7 |
| chr14_-_70809494 | 5.95 |
ENST00000381250.8
ENST00000554752.7 ENST00000555993.6 |
MAP3K9
|
mitogen-activated protein kinase kinase kinase 9 |
| chr1_-_23168847 | 5.90 |
ENST00000418342.5
|
LUZP1
|
leucine zipper protein 1 |
| chr3_+_141487008 | 5.82 |
ENST00000286364.9
ENST00000452898.2 |
RASA2
|
RAS p21 protein activator 2 |
| chr17_-_8190154 | 5.72 |
ENST00000389017.6
|
BORCS6
|
BLOC-1 related complex subunit 6 |
| chr12_-_51324138 | 5.54 |
ENST00000452142.7
|
BIN2
|
bridging integrator 2 |
| chr16_-_79600698 | 5.53 |
ENST00000393350.1
|
MAF
|
MAF bZIP transcription factor |
| chr12_+_53380639 | 5.51 |
ENST00000426431.2
|
SP1
|
Sp1 transcription factor |
| chr6_-_110815408 | 5.49 |
ENST00000368911.8
|
CDK19
|
cyclin dependent kinase 19 |
| chr19_-_11339573 | 5.42 |
ENST00000222120.8
|
RAB3D
|
RAB3D, member RAS oncogene family |
| chr10_-_92243246 | 5.38 |
ENST00000412050.8
ENST00000614585.4 |
CPEB3
|
cytoplasmic polyadenylation element binding protein 3 |
| chr3_-_133895867 | 5.36 |
ENST00000285208.9
|
RAB6B
|
RAB6B, member RAS oncogene family |
| chr17_+_63622406 | 5.36 |
ENST00000579585.5
ENST00000361733.8 ENST00000584573.5 ENST00000361357.7 |
MAP3K3
|
mitogen-activated protein kinase kinase kinase 3 |
| chr20_-_5001474 | 5.31 |
ENST00000338244.6
|
SLC23A2
|
solute carrier family 23 member 2 |
| chr21_-_39313610 | 5.30 |
ENST00000342449.8
ENST00000341322.4 |
BRWD1
|
bromodomain and WD repeat domain containing 1 |
| chr16_-_67719300 | 5.28 |
ENST00000602279.2
ENST00000268797.12 ENST00000602855.2 ENST00000602377.1 |
GFOD2
|
glucose-fructose oxidoreductase domain containing 2 |
| chr10_+_97498881 | 5.24 |
ENST00000370664.4
|
UBTD1
|
ubiquitin domain containing 1 |
| chr18_-_63319987 | 5.21 |
ENST00000398117.1
|
BCL2
|
BCL2 apoptosis regulator |
| chr22_-_36703723 | 5.20 |
ENST00000300105.7
|
CACNG2
|
calcium voltage-gated channel auxiliary subunit gamma 2 |
| chr5_-_141878396 | 5.19 |
ENST00000503492.5
ENST00000287008.8 ENST00000394536.4 |
PCDH1
|
protocadherin 1 |
| chr17_+_21376321 | 5.18 |
ENST00000583088.6
|
KCNJ12
|
potassium inwardly rectifying channel subfamily J member 12 |
| chr14_-_99604167 | 5.16 |
ENST00000380243.9
|
CCDC85C
|
coiled-coil domain containing 85C |
| chr16_-_18926408 | 5.16 |
ENST00000446231.7
|
SMG1
|
SMG1 nonsense mediated mRNA decay associated PI3K related kinase |
| chr8_-_144326908 | 5.16 |
ENST00000332324.5
|
DGAT1
|
diacylglycerol O-acyltransferase 1 |
| chr6_-_79947541 | 5.15 |
ENST00000369816.5
|
ELOVL4
|
ELOVL fatty acid elongase 4 |
| chr1_-_6261053 | 5.13 |
ENST00000377893.3
|
GPR153
|
G protein-coupled receptor 153 |
| chr10_-_49539112 | 5.12 |
ENST00000355832.10
ENST00000447839.7 |
ERCC6
|
ERCC excision repair 6, chromatin remodeling factor |
| chr2_-_208025494 | 5.08 |
ENST00000457206.1
ENST00000427836.8 |
PLEKHM3
|
pleckstrin homology domain containing M3 |
| chr22_+_39994926 | 5.06 |
ENST00000333407.11
|
FAM83F
|
family with sequence similarity 83 member F |
| chr17_-_68291116 | 4.99 |
ENST00000327268.8
ENST00000580666.6 |
SLC16A6
|
solute carrier family 16 member 6 |
| chr17_-_28897602 | 4.97 |
ENST00000394906.6
ENST00000585169.5 |
FLOT2
|
flotillin 2 |
| chr4_+_38664189 | 4.87 |
ENST00000514033.1
ENST00000261438.10 |
KLF3
|
Kruppel like factor 3 |
| chr2_-_50347710 | 4.82 |
ENST00000342183.9
ENST00000401710.5 |
NRXN1
|
neurexin 1 |
| chr4_+_37453914 | 4.62 |
ENST00000381980.9
ENST00000508175.5 |
C4orf19
|
chromosome 4 open reading frame 19 |
| chr6_+_35259703 | 4.53 |
ENST00000373953.8
ENST00000339411.5 |
ZNF76
|
zinc finger protein 76 |
| chr8_+_22999535 | 4.52 |
ENST00000251822.7
|
RHOBTB2
|
Rho related BTB domain containing 2 |
| chr12_-_122896066 | 4.45 |
ENST00000267202.7
ENST00000535765.5 |
VPS37B
|
VPS37B subunit of ESCRT-I |
| chr15_+_85380565 | 4.43 |
ENST00000559362.5
ENST00000394518.7 |
AKAP13
|
A-kinase anchoring protein 13 |
| chr9_-_33167296 | 4.42 |
ENST00000379731.5
ENST00000535206.5 |
B4GALT1
|
beta-1,4-galactosyltransferase 1 |
| chr17_-_5468951 | 4.30 |
ENST00000225296.8
|
DHX33
|
DEAH-box helicase 33 |
| chr10_+_14878848 | 4.29 |
ENST00000433779.5
ENST00000378325.7 ENST00000354919.11 ENST00000313519.9 ENST00000420416.1 |
SUV39H2
|
suppressor of variegation 3-9 homolog 2 |
| chr2_+_176188658 | 4.26 |
ENST00000331462.6
|
HOXD1
|
homeobox D1 |
| chr1_-_217089627 | 4.19 |
ENST00000361525.7
|
ESRRG
|
estrogen related receptor gamma |
| chr1_+_154405193 | 4.19 |
ENST00000622330.4
ENST00000344086.8 |
IL6R
|
interleukin 6 receptor |
| chr3_+_58237501 | 4.12 |
ENST00000295962.8
|
ABHD6
|
abhydrolase domain containing 6, acylglycerol lipase |
| chr12_-_3873346 | 4.10 |
ENST00000427057.6
|
PARP11
|
poly(ADP-ribose) polymerase family member 11 |
| chr12_+_71686061 | 4.06 |
ENST00000266673.10
ENST00000550524.5 |
TMEM19
|
transmembrane protein 19 |
| chr1_+_16367088 | 4.03 |
ENST00000471507.5
ENST00000401089.3 ENST00000401088.9 ENST00000492354.1 |
SZRD1
|
SUZ RNA binding domain containing 1 |
| chr11_-_36510232 | 4.02 |
ENST00000348124.5
ENST00000526995.6 |
TRAF6
|
TNF receptor associated factor 6 |
| chr12_-_116881431 | 4.01 |
ENST00000257572.5
|
HRK
|
harakiri, BCL2 interacting protein |
| chr10_+_102461380 | 3.99 |
ENST00000238936.8
ENST00000369931.3 |
MFSD13A
|
major facilitator superfamily domain containing 13A |
| chr15_-_92655712 | 3.89 |
ENST00000327355.6
|
FAM174B
|
family with sequence similarity 174 member B |
| chr2_+_130356036 | 3.88 |
ENST00000347849.7
ENST00000175756.10 |
PTPN18
|
protein tyrosine phosphatase non-receptor type 18 |
| chr17_-_42181081 | 3.83 |
ENST00000607371.5
|
KCNH4
|
potassium voltage-gated channel subfamily H member 4 |
| chr22_+_29205877 | 3.82 |
ENST00000334018.11
ENST00000429226.5 ENST00000404755.7 ENST00000404820.7 ENST00000430127.1 |
EMID1
|
EMI domain containing 1 |
| chr16_+_68264501 | 3.77 |
ENST00000618043.4
ENST00000219343.11 ENST00000566834.5 ENST00000566454.5 |
SLC7A6
|
solute carrier family 7 member 6 |
| chr9_+_76459152 | 3.75 |
ENST00000444201.6
ENST00000376730.5 |
GCNT1
|
glucosaminyl (N-acetyl) transferase 1 |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.9 | 14.7 | GO:1990654 | regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654) |
| 4.8 | 19.1 | GO:1903070 | negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070) |
| 4.7 | 14.2 | GO:1990168 | protein K33-linked deubiquitination(GO:1990168) |
| 4.5 | 13.5 | GO:0045082 | interleukin-13 biosynthetic process(GO:0042231) positive regulation of interleukin-10 biosynthetic process(GO:0045082) |
| 4.2 | 12.6 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
| 3.6 | 10.9 | GO:0034147 | regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) |
| 3.6 | 10.7 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
| 2.8 | 14.0 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 2.7 | 8.1 | GO:0098928 | presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526) |
| 2.7 | 8.0 | GO:1904395 | positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
| 2.6 | 30.9 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
| 2.6 | 10.2 | GO:0006114 | glycerol biosynthetic process(GO:0006114) |
| 2.4 | 17.0 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
| 2.4 | 21.2 | GO:0035897 | proteolysis in other organism(GO:0035897) |
| 2.3 | 9.3 | GO:0035871 | protein K11-linked deubiquitination(GO:0035871) |
| 2.3 | 6.9 | GO:0071043 | CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) |
| 2.3 | 18.1 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 2.2 | 11.2 | GO:0034959 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
| 2.1 | 6.2 | GO:0061026 | cardiac muscle tissue regeneration(GO:0061026) |
| 2.1 | 12.3 | GO:0007296 | vitellogenesis(GO:0007296) |
| 2.0 | 20.2 | GO:2000049 | positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049) |
| 1.8 | 16.6 | GO:1903748 | negative regulation of establishment of protein localization to mitochondrion(GO:1903748) |
| 1.8 | 5.5 | GO:0036166 | phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239) |
| 1.8 | 9.0 | GO:1903904 | negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107) |
| 1.8 | 5.4 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
| 1.6 | 6.5 | GO:1904379 | protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379) |
| 1.6 | 14.2 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
| 1.5 | 7.7 | GO:0090212 | vitamin E metabolic process(GO:0042360) negative regulation of establishment of blood-brain barrier(GO:0090212) |
| 1.5 | 6.1 | GO:1904154 | positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) |
| 1.5 | 4.5 | GO:1903774 | positive regulation of viral budding via host ESCRT complex(GO:1903774) |
| 1.5 | 4.4 | GO:0005988 | lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) |
| 1.4 | 5.6 | GO:0060023 | soft palate development(GO:0060023) |
| 1.4 | 13.9 | GO:1901538 | DNA methylation involved in embryo development(GO:0043045) histone H3-K4 trimethylation(GO:0080182) changes to DNA methylation involved in embryo development(GO:1901538) |
| 1.4 | 5.4 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
| 1.3 | 5.2 | GO:0046671 | negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671) |
| 1.3 | 7.6 | GO:0002005 | angiotensin catabolic process in blood(GO:0002005) |
| 1.2 | 2.5 | GO:0003342 | proepicardium development(GO:0003342) septum transversum development(GO:0003343) |
| 1.2 | 3.7 | GO:0046619 | optic placode formation involved in camera-type eye formation(GO:0046619) |
| 1.2 | 6.1 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 1.2 | 9.3 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 1.1 | 3.4 | GO:0042137 | sequestering of neurotransmitter(GO:0042137) |
| 1.1 | 4.4 | GO:1900169 | regulation of glucocorticoid mediated signaling pathway(GO:1900169) |
| 1.1 | 19.2 | GO:0006054 | N-acetylneuraminate metabolic process(GO:0006054) |
| 1.0 | 4.2 | GO:0002384 | hepatic immune response(GO:0002384) |
| 1.0 | 6.2 | GO:2000491 | positive regulation of hepatic stellate cell activation(GO:2000491) |
| 1.0 | 5.2 | GO:0099590 | neurotransmitter receptor internalization(GO:0099590) |
| 1.0 | 11.1 | GO:0030578 | PML body organization(GO:0030578) positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996) |
| 1.0 | 7.7 | GO:0046684 | response to pyrethroid(GO:0046684) |
| 0.9 | 10.4 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
| 0.9 | 17.9 | GO:0010960 | magnesium ion homeostasis(GO:0010960) |
| 0.9 | 3.7 | GO:0035627 | ceramide transport(GO:0035627) |
| 0.9 | 10.1 | GO:0034472 | snRNA 3'-end processing(GO:0034472) |
| 0.9 | 7.3 | GO:0035234 | luteolysis(GO:0001554) ectopic germ cell programmed cell death(GO:0035234) |
| 0.9 | 24.9 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 0.9 | 8.9 | GO:0002480 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) |
| 0.9 | 6.2 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
| 0.9 | 9.4 | GO:0097011 | cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012) |
| 0.8 | 2.5 | GO:1901994 | meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994) |
| 0.8 | 2.5 | GO:0003358 | noradrenergic neuron development(GO:0003358) |
| 0.8 | 8.4 | GO:0071321 | cellular response to cGMP(GO:0071321) |
| 0.8 | 3.2 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 0.8 | 6.3 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.8 | 2.3 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.7 | 2.2 | GO:1901492 | positive regulation of lymphangiogenesis(GO:1901492) |
| 0.7 | 8.9 | GO:0021702 | cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) |
| 0.7 | 5.0 | GO:1903903 | regulation of establishment of T cell polarity(GO:1903903) |
| 0.7 | 24.2 | GO:0008053 | mitochondrial fusion(GO:0008053) |
| 0.7 | 2.7 | GO:1990086 | lens fiber cell apoptotic process(GO:1990086) |
| 0.7 | 6.7 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.7 | 14.0 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
| 0.7 | 8.6 | GO:0035020 | regulation of Rac protein signal transduction(GO:0035020) |
| 0.6 | 3.2 | GO:0010701 | positive regulation of norepinephrine secretion(GO:0010701) |
| 0.6 | 6.4 | GO:0051005 | negative regulation of lipoprotein lipase activity(GO:0051005) |
| 0.6 | 13.7 | GO:2000178 | negative regulation of neural precursor cell proliferation(GO:2000178) |
| 0.6 | 1.2 | GO:0090370 | negative regulation of cholesterol efflux(GO:0090370) |
| 0.6 | 4.3 | GO:0036123 | histone H3-K9 dimethylation(GO:0036123) |
| 0.6 | 15.1 | GO:0036152 | phosphatidylethanolamine acyl-chain remodeling(GO:0036152) |
| 0.6 | 13.5 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.6 | 2.8 | GO:0097155 | embryonic heart tube left/right pattern formation(GO:0060971) fasciculation of sensory neuron axon(GO:0097155) |
| 0.6 | 5.6 | GO:0035461 | vitamin transmembrane transport(GO:0035461) |
| 0.5 | 3.3 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
| 0.5 | 2.2 | GO:0072107 | regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107) |
| 0.5 | 7.0 | GO:0042354 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.5 | 3.6 | GO:0001767 | establishment of lymphocyte polarity(GO:0001767) |
| 0.5 | 1.6 | GO:0061113 | pancreas morphogenesis(GO:0061113) |
| 0.5 | 1.5 | GO:0050928 | negative regulation of positive chemotaxis(GO:0050928) |
| 0.5 | 13.1 | GO:0045109 | intermediate filament organization(GO:0045109) |
| 0.5 | 2.5 | GO:1904674 | positive regulation of somatic stem cell population maintenance(GO:1904674) regulation of stem cell division(GO:2000035) |
| 0.5 | 12.3 | GO:0010763 | positive regulation of fibroblast migration(GO:0010763) |
| 0.5 | 1.9 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
| 0.5 | 6.7 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
| 0.5 | 7.5 | GO:0055089 | fatty acid homeostasis(GO:0055089) |
| 0.5 | 3.8 | GO:0060352 | cell adhesion molecule production(GO:0060352) |
| 0.5 | 16.5 | GO:0035066 | positive regulation of histone acetylation(GO:0035066) |
| 0.5 | 4.1 | GO:2000124 | regulation of endocannabinoid signaling pathway(GO:2000124) |
| 0.5 | 6.3 | GO:0006975 | DNA damage induced protein phosphorylation(GO:0006975) |
| 0.5 | 2.7 | GO:0045410 | positive regulation of interleukin-6 biosynthetic process(GO:0045410) |
| 0.4 | 2.2 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
| 0.4 | 6.7 | GO:0045475 | locomotor rhythm(GO:0045475) |
| 0.4 | 3.5 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.4 | 4.8 | GO:0097107 | postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 0.4 | 25.3 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.4 | 1.3 | GO:1903465 | vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830) |
| 0.4 | 11.7 | GO:0034035 | purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427) |
| 0.4 | 7.8 | GO:0071786 | endoplasmic reticulum tubular network organization(GO:0071786) |
| 0.4 | 5.2 | GO:0032927 | positive regulation of activin receptor signaling pathway(GO:0032927) |
| 0.4 | 5.9 | GO:0001842 | neural fold formation(GO:0001842) |
| 0.4 | 0.8 | GO:0033023 | mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) |
| 0.4 | 1.5 | GO:0014053 | negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) positive regulation of prolactin secretion(GO:1902722) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450) |
| 0.4 | 2.3 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.4 | 4.1 | GO:0070102 | interleukin-6-mediated signaling pathway(GO:0070102) |
| 0.4 | 2.2 | GO:0030579 | ubiquitin-dependent SMAD protein catabolic process(GO:0030579) |
| 0.4 | 6.1 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.4 | 8.6 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 0.4 | 18.1 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.3 | 9.0 | GO:1903846 | positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846) |
| 0.3 | 9.0 | GO:0006829 | zinc II ion transport(GO:0006829) |
| 0.3 | 5.4 | GO:1900745 | positive regulation of p38MAPK cascade(GO:1900745) |
| 0.3 | 11.8 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.3 | 6.5 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
| 0.3 | 1.7 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
| 0.3 | 0.8 | GO:1902202 | regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) |
| 0.3 | 5.5 | GO:0097320 | membrane tubulation(GO:0097320) |
| 0.3 | 2.5 | GO:0048712 | negative regulation of astrocyte differentiation(GO:0048712) |
| 0.3 | 12.7 | GO:0006336 | DNA replication-independent nucleosome assembly(GO:0006336) |
| 0.2 | 7.7 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 0.2 | 11.1 | GO:0071431 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.2 | 7.5 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.2 | 1.5 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.2 | 4.6 | GO:0030970 | retrograde protein transport, ER to cytosol(GO:0030970) |
| 0.2 | 6.9 | GO:0071218 | cellular response to misfolded protein(GO:0071218) |
| 0.2 | 4.0 | GO:0032464 | positive regulation of protein homooligomerization(GO:0032464) |
| 0.2 | 1.9 | GO:0061158 | 3'-UTR-mediated mRNA destabilization(GO:0061158) |
| 0.2 | 3.6 | GO:2000353 | positive regulation of endothelial cell apoptotic process(GO:2000353) |
| 0.2 | 8.0 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
| 0.2 | 3.0 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 0.2 | 1.7 | GO:0002371 | dendritic cell cytokine production(GO:0002371) |
| 0.2 | 6.2 | GO:0043029 | T cell homeostasis(GO:0043029) |
| 0.2 | 3.5 | GO:0002467 | germinal center formation(GO:0002467) |
| 0.2 | 3.3 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.2 | 5.5 | GO:0030220 | platelet formation(GO:0030220) |
| 0.2 | 2.7 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
| 0.2 | 4.5 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.2 | 9.2 | GO:0002755 | MyD88-dependent toll-like receptor signaling pathway(GO:0002755) |
| 0.2 | 3.3 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
| 0.2 | 4.3 | GO:0045943 | positive regulation of transcription from RNA polymerase I promoter(GO:0045943) |
| 0.2 | 1.2 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 0.2 | 0.8 | GO:0006655 | phosphatidylglycerol biosynthetic process(GO:0006655) |
| 0.2 | 10.1 | GO:1902108 | regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108) |
| 0.1 | 8.3 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.1 | 2.2 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.1 | 0.8 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.1 | 1.5 | GO:0051964 | negative regulation of collateral sprouting(GO:0048671) negative regulation of synapse assembly(GO:0051964) |
| 0.1 | 5.5 | GO:0070306 | lens fiber cell differentiation(GO:0070306) |
| 0.1 | 13.7 | GO:0071427 | mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427) |
| 0.1 | 0.7 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
| 0.1 | 2.9 | GO:0048935 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.1 | 6.0 | GO:0016486 | peptide hormone processing(GO:0016486) |
| 0.1 | 2.2 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
| 0.1 | 0.5 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.1 | 1.4 | GO:0021670 | lateral ventricle development(GO:0021670) |
| 0.1 | 7.4 | GO:0010830 | regulation of myotube differentiation(GO:0010830) |
| 0.1 | 0.8 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 0.1 | 3.0 | GO:0010842 | retina layer formation(GO:0010842) |
| 0.1 | 3.3 | GO:0043536 | positive regulation of blood vessel endothelial cell migration(GO:0043536) |
| 0.1 | 1.8 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
| 0.1 | 12.4 | GO:0031532 | actin cytoskeleton reorganization(GO:0031532) |
| 0.1 | 0.8 | GO:0031087 | nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 0.1 | 1.9 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.1 | 2.5 | GO:0006098 | pentose-phosphate shunt(GO:0006098) |
| 0.1 | 10.4 | GO:0050728 | negative regulation of inflammatory response(GO:0050728) |
| 0.1 | 5.8 | GO:0046580 | negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058) |
| 0.1 | 3.0 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.1 | 0.8 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 0.1 | 5.1 | GO:0009584 | detection of visible light(GO:0009584) |
| 0.1 | 7.5 | GO:0001657 | ureteric bud development(GO:0001657) |
| 0.1 | 2.0 | GO:0010919 | regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732) |
| 0.1 | 4.2 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.1 | 3.1 | GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197) |
| 0.1 | 4.2 | GO:0007528 | neuromuscular junction development(GO:0007528) |
| 0.1 | 6.4 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.1 | 4.2 | GO:0048384 | retinoic acid receptor signaling pathway(GO:0048384) |
| 0.1 | 2.4 | GO:0000083 | regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083) |
| 0.1 | 10.0 | GO:0051291 | protein heterooligomerization(GO:0051291) |
| 0.1 | 0.6 | GO:0015732 | prostaglandin transport(GO:0015732) |
| 0.1 | 3.5 | GO:0051973 | positive regulation of telomerase activity(GO:0051973) |
| 0.1 | 10.3 | GO:0006368 | transcription elongation from RNA polymerase II promoter(GO:0006368) |
| 0.1 | 6.4 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 0.1 | 14.6 | GO:0007601 | visual perception(GO:0007601) |
| 0.1 | 1.7 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
| 0.1 | 4.8 | GO:0032418 | lysosome localization(GO:0032418) |
| 0.1 | 0.3 | GO:0046167 | glycerol-3-phosphate biosynthetic process(GO:0046167) |
| 0.1 | 3.4 | GO:0042982 | amyloid precursor protein metabolic process(GO:0042982) |
| 0.1 | 3.1 | GO:0046686 | response to cadmium ion(GO:0046686) |
| 0.1 | 3.5 | GO:0051865 | protein autoubiquitination(GO:0051865) |
| 0.1 | 1.7 | GO:1900078 | positive regulation of cellular response to insulin stimulus(GO:1900078) |
| 0.1 | 4.4 | GO:0050729 | positive regulation of inflammatory response(GO:0050729) |
| 0.1 | 3.0 | GO:0019933 | cAMP-mediated signaling(GO:0019933) |
| 0.1 | 1.5 | GO:0035025 | positive regulation of Rho protein signal transduction(GO:0035025) |
| 0.1 | 0.8 | GO:0045577 | regulation of B cell differentiation(GO:0045577) |
| 0.1 | 3.6 | GO:0030593 | neutrophil chemotaxis(GO:0030593) |
| 0.1 | 0.6 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.1 | 0.4 | GO:0048149 | behavioral response to ethanol(GO:0048149) |
| 0.0 | 0.1 | GO:0015783 | GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079) |
| 0.0 | 4.3 | GO:0019233 | sensory perception of pain(GO:0019233) |
| 0.0 | 0.3 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.0 | 7.1 | GO:0071805 | cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805) |
| 0.0 | 5.0 | GO:0015718 | monocarboxylic acid transport(GO:0015718) |
| 0.0 | 1.0 | GO:1901185 | negative regulation of ERBB signaling pathway(GO:1901185) |
| 0.0 | 0.3 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
| 0.0 | 0.3 | GO:0034378 | chylomicron assembly(GO:0034378) |
| 0.0 | 7.2 | GO:0051056 | regulation of small GTPase mediated signal transduction(GO:0051056) |
| 0.0 | 2.3 | GO:0000725 | double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725) |
| 0.0 | 4.1 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.0 | 1.2 | GO:0001938 | positive regulation of endothelial cell proliferation(GO:0001938) |
| 0.0 | 6.9 | GO:0090305 | nucleic acid phosphodiester bond hydrolysis(GO:0090305) |
| 0.0 | 4.7 | GO:0006367 | transcription initiation from RNA polymerase II promoter(GO:0006367) |
| 0.0 | 0.3 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.0 | 0.6 | GO:2000785 | regulation of autophagosome assembly(GO:2000785) |
| 0.0 | 1.1 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 0.0 | 0.2 | GO:0042481 | regulation of odontogenesis(GO:0042481) |
| 0.0 | 2.6 | GO:0070997 | neuron death(GO:0070997) |
| 0.0 | 1.0 | GO:0006310 | DNA recombination(GO:0006310) |
| 0.0 | 1.7 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.5 | 14.0 | GO:0035363 | histone locus body(GO:0035363) |
| 3.1 | 9.4 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 3.0 | 17.8 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 2.7 | 8.1 | GO:0048788 | cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569) |
| 2.6 | 7.7 | GO:0031251 | PAN complex(GO:0031251) |
| 2.4 | 19.1 | GO:0097425 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 2.3 | 13.9 | GO:0001940 | male pronucleus(GO:0001940) |
| 2.2 | 11.2 | GO:0031302 | intrinsic component of endosome membrane(GO:0031302) |
| 1.9 | 13.5 | GO:0000788 | nuclear nucleosome(GO:0000788) |
| 1.9 | 7.7 | GO:0034678 | integrin alpha8-beta1 complex(GO:0034678) |
| 1.8 | 8.9 | GO:0031905 | early endosome lumen(GO:0031905) |
| 1.4 | 22.9 | GO:0035102 | PRC1 complex(GO:0035102) |
| 1.3 | 9.2 | GO:0043196 | varicosity(GO:0043196) |
| 1.0 | 16.5 | GO:0030914 | STAGA complex(GO:0030914) |
| 1.0 | 6.7 | GO:0036157 | outer dynein arm(GO:0036157) |
| 1.0 | 13.4 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 1.0 | 8.6 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.9 | 10.1 | GO:0032039 | integrator complex(GO:0032039) |
| 0.8 | 4.2 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.8 | 9.0 | GO:0060171 | stereocilium membrane(GO:0060171) |
| 0.8 | 7.9 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.7 | 3.7 | GO:0000836 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
| 0.7 | 7.0 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.7 | 2.0 | GO:0005592 | collagen type XI trimer(GO:0005592) |
| 0.6 | 21.5 | GO:0032809 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.6 | 4.4 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 0.5 | 6.9 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.5 | 4.5 | GO:0000813 | ESCRT I complex(GO:0000813) |
| 0.4 | 3.5 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.4 | 3.4 | GO:0060203 | clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203) |
| 0.4 | 8.4 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.4 | 2.5 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.4 | 1.5 | GO:0032144 | 4-aminobutyrate transaminase complex(GO:0032144) |
| 0.4 | 5.2 | GO:0098839 | postsynaptic density membrane(GO:0098839) |
| 0.3 | 7.7 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.3 | 3.7 | GO:0070776 | H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776) |
| 0.3 | 5.8 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.3 | 1.2 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.3 | 22.0 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.3 | 3.6 | GO:0071203 | WASH complex(GO:0071203) |
| 0.3 | 3.0 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.3 | 12.8 | GO:0009925 | basal plasma membrane(GO:0009925) |
| 0.3 | 5.4 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.3 | 1.7 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.3 | 23.5 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.3 | 3.1 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.3 | 4.0 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.2 | 5.4 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.2 | 28.8 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.2 | 5.0 | GO:0001931 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.2 | 1.2 | GO:0032444 | activin responsive factor complex(GO:0032444) |
| 0.2 | 2.6 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
| 0.2 | 5.5 | GO:0001891 | phagocytic cup(GO:0001891) |
| 0.2 | 13.1 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.2 | 6.2 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.2 | 4.1 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.2 | 3.9 | GO:0046930 | pore complex(GO:0046930) |
| 0.2 | 7.0 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.2 | 24.4 | GO:0034705 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
| 0.2 | 32.4 | GO:0005923 | bicellular tight junction(GO:0005923) |
| 0.2 | 5.2 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.2 | 0.9 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
| 0.1 | 1.5 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.1 | 5.5 | GO:0016592 | mediator complex(GO:0016592) |
| 0.1 | 7.4 | GO:0005795 | Golgi stack(GO:0005795) |
| 0.1 | 2.4 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 11.1 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
| 0.1 | 2.2 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.1 | 9.0 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.1 | 2.7 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.1 | 0.8 | GO:0098576 | lumenal side of membrane(GO:0098576) |
| 0.1 | 0.8 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.1 | 14.5 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.1 | 6.1 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.1 | 4.2 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.1 | 4.8 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 15.5 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.1 | 28.0 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.1 | 1.3 | GO:0071437 | invadopodium(GO:0071437) |
| 0.1 | 0.7 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
| 0.1 | 1.9 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.1 | 0.7 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.0 | 15.7 | GO:0098852 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.0 | 5.0 | GO:0019897 | extrinsic component of plasma membrane(GO:0019897) |
| 0.0 | 4.5 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.8 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 5.2 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.0 | 2.3 | GO:1990391 | DNA repair complex(GO:1990391) |
| 0.0 | 1.7 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 1.9 | GO:0030665 | clathrin-coated vesicle membrane(GO:0030665) |
| 0.0 | 14.7 | GO:0016604 | nuclear body(GO:0016604) |
| 0.0 | 2.3 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.0 | 67.8 | GO:0005829 | cytosol(GO:0005829) |
| 0.0 | 0.3 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 12.6 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.0 | 36.1 | GO:0005887 | integral component of plasma membrane(GO:0005887) |
| 0.0 | 115.5 | GO:0005634 | nucleus(GO:0005634) |
| 0.0 | 2.5 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 1.1 | GO:0031225 | anchored component of membrane(GO:0031225) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.7 | 14.2 | GO:1904455 | ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455) |
| 3.6 | 10.7 | GO:0035575 | histone demethylase activity (H4-K20 specific)(GO:0035575) |
| 3.4 | 10.2 | GO:0098519 | nucleotide phosphatase activity, acting on free nucleotides(GO:0098519) |
| 3.2 | 12.9 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 3.1 | 9.3 | GO:0080130 | L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130) |
| 2.6 | 7.7 | GO:0008431 | vitamin E binding(GO:0008431) |
| 2.5 | 7.4 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
| 2.4 | 14.2 | GO:0047696 | beta-adrenergic receptor kinase activity(GO:0047696) |
| 2.4 | 11.8 | GO:0003835 | beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835) |
| 1.8 | 10.9 | GO:0035252 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 1.8 | 5.3 | GO:0008523 | sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) |
| 1.7 | 5.2 | GO:0004144 | diacylglycerol O-acyltransferase activity(GO:0004144) |
| 1.7 | 15.1 | GO:0047144 | 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144) |
| 1.7 | 8.4 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 1.5 | 8.9 | GO:0008142 | oxysterol binding(GO:0008142) |
| 1.4 | 17.4 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 1.4 | 4.2 | GO:0070119 | ciliary neurotrophic factor binding(GO:0070119) |
| 1.3 | 25.8 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 1.3 | 16.6 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 1.3 | 3.8 | GO:0003829 | beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829) |
| 1.2 | 7.3 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 1.1 | 28.3 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 1.1 | 4.4 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 1.1 | 6.4 | GO:0010465 | nerve growth factor receptor activity(GO:0010465) |
| 1.0 | 7.7 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 1.0 | 6.7 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 1.0 | 34.4 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.9 | 11.4 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.9 | 10.4 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.9 | 3.7 | GO:0097001 | ceramide binding(GO:0097001) |
| 0.9 | 6.3 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
| 0.8 | 2.5 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
| 0.8 | 12.6 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 0.8 | 19.1 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.8 | 2.4 | GO:0050405 | [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405) |
| 0.8 | 7.0 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
| 0.7 | 24.9 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.7 | 39.5 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 0.7 | 5.1 | GO:0035198 | miRNA binding(GO:0035198) |
| 0.7 | 4.3 | GO:1904047 | S-adenosyl-L-methionine binding(GO:1904047) |
| 0.7 | 3.4 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.7 | 13.5 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.6 | 11.7 | GO:0004062 | aryl sulfotransferase activity(GO:0004062) |
| 0.6 | 4.3 | GO:0000182 | rDNA binding(GO:0000182) |
| 0.6 | 9.5 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.6 | 9.4 | GO:0017151 | DEAD/H-box RNA helicase binding(GO:0017151) |
| 0.5 | 3.2 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.5 | 3.7 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
| 0.5 | 6.3 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.5 | 6.7 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.5 | 4.2 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 0.5 | 14.5 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.4 | 8.3 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.4 | 5.1 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.4 | 7.7 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.4 | 10.8 | GO:0031489 | myosin V binding(GO:0031489) |
| 0.4 | 1.2 | GO:0000247 | C-8 sterol isomerase activity(GO:0000247) |
| 0.4 | 6.2 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.4 | 6.1 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.4 | 2.0 | GO:0004991 | parathyroid hormone receptor activity(GO:0004991) |
| 0.4 | 9.7 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.4 | 18.1 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.4 | 5.9 | GO:0070411 | I-SMAD binding(GO:0070411) |
| 0.4 | 1.5 | GO:0047298 | 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298) |
| 0.4 | 3.7 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.4 | 4.1 | GO:0017002 | activin-activated receptor activity(GO:0017002) |
| 0.4 | 4.0 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.4 | 20.3 | GO:0001205 | transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205) |
| 0.4 | 6.9 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
| 0.3 | 2.7 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.3 | 5.4 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.3 | 10.4 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.3 | 14.7 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.3 | 2.5 | GO:0010385 | double-stranded methylated DNA binding(GO:0010385) |
| 0.3 | 18.7 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.3 | 4.4 | GO:0005078 | cAMP-dependent protein kinase activity(GO:0004691) MAP-kinase scaffold activity(GO:0005078) |
| 0.3 | 3.9 | GO:0004726 | non-membrane spanning protein tyrosine phosphatase activity(GO:0004726) |
| 0.3 | 11.4 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.3 | 13.9 | GO:0016706 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706) |
| 0.3 | 0.8 | GO:0003858 | 3-hydroxybutyrate dehydrogenase activity(GO:0003858) |
| 0.3 | 26.9 | GO:0101005 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.3 | 21.8 | GO:0004879 | RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531) |
| 0.3 | 3.3 | GO:0005168 | neurotrophin TRKA receptor binding(GO:0005168) |
| 0.2 | 12.2 | GO:0042162 | telomeric DNA binding(GO:0042162) |
| 0.2 | 7.3 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.2 | 3.0 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.2 | 11.2 | GO:0017046 | peptide hormone binding(GO:0017046) |
| 0.2 | 2.0 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
| 0.2 | 18.8 | GO:0035254 | glutamate receptor binding(GO:0035254) |
| 0.2 | 4.8 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 0.2 | 8.6 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.2 | 13.5 | GO:0016278 | lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279) |
| 0.2 | 2.9 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
| 0.2 | 8.5 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.2 | 1.5 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.2 | 1.1 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.2 | 1.7 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.2 | 1.5 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
| 0.2 | 4.9 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.2 | 0.8 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.1 | 7.4 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.1 | 21.8 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.1 | 3.1 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.1 | 4.2 | GO:0008331 | high voltage-gated calcium channel activity(GO:0008331) |
| 0.1 | 3.6 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.1 | 3.0 | GO:0030552 | cAMP binding(GO:0030552) |
| 0.1 | 14.0 | GO:0051117 | ATPase binding(GO:0051117) |
| 0.1 | 2.6 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 1.9 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.1 | 4.1 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.1 | 6.2 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.1 | 36.7 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.1 | 1.5 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.1 | 3.7 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.1 | 1.3 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
| 0.1 | 3.6 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.1 | 1.2 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.1 | 2.1 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 0.1 | 0.3 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 0.1 | 5.2 | GO:0008028 | monocarboxylic acid transmembrane transporter activity(GO:0008028) |
| 0.1 | 1.3 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.1 | 1.7 | GO:0001163 | RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164) |
| 0.1 | 1.8 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 2.2 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.1 | 0.8 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 0.1 | 2.6 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.1 | 9.0 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.1 | 2.6 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.1 | 0.3 | GO:0004370 | glycerol kinase activity(GO:0004370) |
| 0.1 | 13.6 | GO:0008083 | growth factor activity(GO:0008083) |
| 0.1 | 0.8 | GO:0070567 | cytidylyltransferase activity(GO:0070567) |
| 0.1 | 3.8 | GO:0015297 | antiporter activity(GO:0015297) |
| 0.1 | 0.8 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 0.1 | 7.9 | GO:0004519 | endonuclease activity(GO:0004519) |
| 0.1 | 4.5 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
| 0.1 | 5.2 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 0.1 | 1.1 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 0.1 | 0.7 | GO:0043495 | protein anchor(GO:0043495) |
| 0.0 | 0.1 | GO:0005457 | GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080) |
| 0.0 | 2.9 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 32.9 | GO:0001071 | nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700) |
| 0.0 | 0.5 | GO:0016868 | intramolecular transferase activity, phosphotransferases(GO:0016868) |
| 0.0 | 11.1 | GO:0046982 | protein heterodimerization activity(GO:0046982) |
| 0.0 | 1.4 | GO:0030971 | receptor tyrosine kinase binding(GO:0030971) |
| 0.0 | 12.2 | GO:0004674 | protein serine/threonine kinase activity(GO:0004674) |
| 0.0 | 2.3 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.0 | 0.7 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.0 | 0.6 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.0 | 0.5 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.0 | 6.0 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 2.2 | GO:0002020 | protease binding(GO:0002020) |
| 0.0 | 0.1 | GO:0015288 | porin activity(GO:0015288) |
| 0.0 | 4.3 | GO:0003682 | chromatin binding(GO:0003682) |
| 0.0 | 2.0 | GO:0003774 | motor activity(GO:0003774) |
| 0.0 | 4.0 | GO:0005543 | phospholipid binding(GO:0005543) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 74.4 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.5 | 15.1 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.4 | 6.3 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.4 | 3.4 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.4 | 7.0 | ST STAT3 PATHWAY | STAT3 Pathway |
| 0.4 | 19.8 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.4 | 12.3 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.3 | 14.5 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.3 | 8.6 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.3 | 7.3 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.3 | 12.5 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 0.3 | 8.1 | SA B CELL RECEPTOR COMPLEXES | Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases. |
| 0.2 | 11.3 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.2 | 18.5 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.2 | 7.7 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.2 | 4.8 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.2 | 2.7 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.2 | 18.3 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.2 | 10.2 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.2 | 2.5 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.1 | 10.1 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.1 | 5.0 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.1 | 21.9 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.1 | 3.5 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.1 | 1.2 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.1 | 44.3 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 11.8 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.1 | 5.4 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.1 | 4.3 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.1 | 7.0 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.1 | 6.9 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.1 | 1.5 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.1 | 4.1 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.1 | 1.7 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.1 | 18.3 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 2.1 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.1 | 4.4 | PID THROMBIN PAR1 PATHWAY | PAR1-mediated thrombin signaling events |
| 0.1 | 2.0 | PID INTEGRIN1 PATHWAY | Beta1 integrin cell surface interactions |
| 0.1 | 4.2 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.1 | 2.3 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.0 | 1.3 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 0.0 | 0.9 | ST ADRENERGIC | Adrenergic Pathway |
| 0.0 | 0.6 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 10.2 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.9 | 21.8 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.8 | 8.9 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.8 | 24.8 | REACTOME NOD1 2 SIGNALING PATHWAY | Genes involved in NOD1/2 Signaling Pathway |
| 0.7 | 15.1 | REACTOME ACYL CHAIN REMODELLING OF PE | Genes involved in Acyl chain remodelling of PE |
| 0.6 | 14.6 | REACTOME N GLYCAN ANTENNAE ELONGATION | Genes involved in N-Glycan antennae elongation |
| 0.6 | 6.9 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.5 | 11.7 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.4 | 25.4 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.4 | 4.5 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.4 | 14.0 | REACTOME ELONGATION ARREST AND RECOVERY | Genes involved in Elongation arrest and recovery |
| 0.3 | 4.2 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.3 | 34.3 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.3 | 11.5 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.3 | 8.6 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.3 | 11.1 | REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
| 0.3 | 8.6 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.3 | 4.7 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.2 | 5.2 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.2 | 8.3 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 0.2 | 32.6 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.2 | 5.1 | REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX | Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex |
| 0.2 | 8.4 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 0.2 | 7.7 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.2 | 0.8 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.2 | 2.7 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.2 | 1.5 | REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT | Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript |
| 0.2 | 8.0 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.2 | 13.1 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.2 | 6.2 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.2 | 3.7 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.2 | 9.9 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.2 | 4.1 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.2 | 4.9 | REACTOME TRAF6 MEDIATED NFKB ACTIVATION | Genes involved in TRAF6 mediated NF-kB activation |
| 0.2 | 5.4 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.2 | 13.0 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
| 0.1 | 3.7 | REACTOME SIGNALING BY ROBO RECEPTOR | Genes involved in Signaling by Robo receptor |
| 0.1 | 1.5 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.1 | 2.4 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.1 | 5.2 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.1 | 20.1 | REACTOME G ALPHA S SIGNALLING EVENTS | Genes involved in G alpha (s) signalling events |
| 0.1 | 6.3 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.1 | 1.5 | REACTOME TIE2 SIGNALING | Genes involved in Tie2 Signaling |
| 0.1 | 3.5 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.1 | 1.5 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.1 | 3.2 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.1 | 0.7 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.1 | 13.0 | REACTOME G ALPHA Q SIGNALLING EVENTS | Genes involved in G alpha (q) signalling events |
| 0.1 | 0.8 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.1 | 5.4 | REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS | Genes involved in Glycerophospholipid biosynthesis |
| 0.1 | 5.3 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 6.0 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 2.0 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.0 | 6.9 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 0.8 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.0 | 1.5 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.0 | 2.4 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 0.6 | REACTOME TRANSPORT OF ORGANIC ANIONS | Genes involved in Transport of organic anions |
| 0.0 | 0.5 | REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 2.8 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.0 | 0.6 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 0.3 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |