avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
CEBPB Links Ensembl NCBI GeneCards UniProt	ENSG00000172216.6	CEBPB

Gene	Promoter	Pearson corr. coef.	P-value	Plot
CEBPB	hg38_v1_chr20_+_50190821_50190839	0.45	2.6e-12	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr20_+_380747 Show fit	20.48	ENST00000217233.9	TRIB3 Links Ensembl NCBI GeneCards UniProt Show fit	tribbles pseudokinase 3
chr12_+_57230301 Show fit	18.57	ENST00000553474.5	SHMT2 Links Ensembl NCBI GeneCards UniProt Show fit	serine hydroxymethyltransferase 2
chr12_+_57230336 Show fit	18.05	ENST00000555773.5 ENST00000554975.5 ENST00000449049.7	SHMT2 Links Ensembl NCBI GeneCards UniProt Show fit	serine hydroxymethyltransferase 2
chr12_+_57230086 Show fit	15.51	ENST00000414700.7 ENST00000557703.5	SHMT2 Links Ensembl NCBI GeneCards UniProt Show fit	serine hydroxymethyltransferase 2
chr4_-_138242325 Show fit	11.50	ENST00000280612.9	SLC7A11 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 7 member 11
chr5_+_33440947 Show fit	11.45	ENST00000455217.6 ENST00000265112.8	TARS1 Links Ensembl NCBI GeneCards UniProt Show fit	threonyl-tRNA synthetase 1
chr5_+_33440696 Show fit	10.99	ENST00000502553.5 ENST00000514259.5	TARS1 Links Ensembl NCBI GeneCards UniProt Show fit	threonyl-tRNA synthetase 1
chr14_-_100375333 Show fit	10.64	ENST00000557297.5 ENST00000555813.5 ENST00000392882.7 ENST00000557135.5 ENST00000556698.5 ENST00000554509.5 ENST00000555410.5	WARS1 Links Ensembl NCBI GeneCards UniProt Show fit	tryptophanyl-tRNA synthetase 1
chr1_+_212608628 Show fit	10.28	ENST00000613954.4 ENST00000341491.9 ENST00000366985.5	ATF3 Links Ensembl NCBI GeneCards UniProt Show fit	activating transcription factor 3
chr12_+_57229694 Show fit	9.80	ENST00000557487.5 ENST00000328923.8 ENST00000555634.5 ENST00000556689.5	SHMT2 Links Ensembl NCBI GeneCards UniProt Show fit	serine hydroxymethyltransferase 2
chr1_+_98661666 Show fit	9.42	ENST00000529992.5	SNX7 Links Ensembl NCBI GeneCards UniProt Show fit	sorting nexin 7
chrX_-_110440218 Show fit	9.07	ENST00000372057.1 ENST00000372054.3	AMMECR1 Links Ensembl NCBI GeneCards UniProt Show fit GNG5P2 Links Ensembl NCBI GeneCards UniProt Show fit	AMMECR nuclear protein 1 G protein subunit gamma 5 pseudogene 2
chr14_-_100375602 Show fit	8.85	ENST00000553395.5 ENST00000553545.5 ENST00000344102.9 ENST00000556338.5 ENST00000553934.1	WARS1 Links Ensembl NCBI GeneCards UniProt Show fit	tryptophanyl-tRNA synthetase 1
chr11_+_114296347 Show fit	8.63	ENST00000299964.4	NNMT Links Ensembl NCBI GeneCards UniProt Show fit	nicotinamide N-methyltransferase
chr19_-_46784733 Show fit	8.45	ENST00000593713.1 ENST00000598022.1 ENST00000434726.6	SLC1A5 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 member 5
chr19_-_46784905 Show fit	8.04	ENST00000594991.5	SLC1A5 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 member 5
chr3_+_157436842 Show fit	8.01	ENST00000295927.4	PTX3 Links Ensembl NCBI GeneCards UniProt Show fit	pentraxin 3
chr9_-_92293674 Show fit	7.99	ENST00000683679.1 ENST00000683565.1 ENST00000684557.1 ENST00000682578.1 ENST00000443024.7 ENST00000375643.7 ENST00000683469.1	IARS1 Links Ensembl NCBI GeneCards UniProt Show fit	isoleucyl-tRNA synthetase 1
chr17_-_81937221 Show fit	7.71	ENST00000402252.6 ENST00000583564.5 ENST00000585244.1 ENST00000337943.9 ENST00000579698.5	PYCR1 Links Ensembl NCBI GeneCards UniProt Show fit	pyrroline-5-carboxylate reductase 1
chr17_+_41689862 Show fit	7.68	ENST00000586699.1	EIF1 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 1
chr6_+_30720335 Show fit	7.32	ENST00000327892.13	TUBB Links Ensembl NCBI GeneCards UniProt Show fit	tubulin beta class I
chr1_+_53014926 Show fit	7.09	ENST00000430330.6 ENST00000408941.7 ENST00000478274.6 ENST00000484100.5 ENST00000435345.6 ENST00000488965.1	SCP2 Links Ensembl NCBI GeneCards UniProt Show fit	sterol carrier protein 2
chr17_-_81937277 Show fit	6.99	ENST00000405481.8 ENST00000329875.13 ENST00000585215.5	PYCR1 Links Ensembl NCBI GeneCards UniProt Show fit	pyrroline-5-carboxylate reductase 1
chr15_-_82571741 Show fit	6.96	ENST00000562833.2 ENST00000611163.4	ENSG00000260836.2 Links Ensembl NCBI GeneCards UniProt Show fit CPEB1 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein cytoplasmic polyadenylation element binding protein 1
chr17_-_66220630 Show fit	6.73	ENST00000585162.1	APOH Links Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein H
chrX_+_24054931 Show fit	6.71	ENST00000253039.9 ENST00000423068.1	EIF2S3 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 2 subunit gamma
chr6_-_32844643 Show fit	6.71	ENST00000374881.3	PSMB8 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit beta 8
chr17_-_81937320 Show fit	6.70	ENST00000577624.5 ENST00000403172.8 ENST00000619204.4 ENST00000629768.2	PYCR1 Links Ensembl NCBI GeneCards UniProt Show fit	pyrroline-5-carboxylate reductase 1
chr5_-_138543198 Show fit	6.67	ENST00000507939.5 ENST00000572514.5 ENST00000499810.6 ENST00000360541.10	ETF1 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation termination factor 1
chr1_-_36482904 Show fit	6.45	ENST00000373106.6	CSF3R Links Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 3 receptor
chr1_-_32817311 Show fit	6.20	ENST00000373477.9 ENST00000675785.1	YARS1 Links Ensembl NCBI GeneCards UniProt Show fit	tyrosyl-tRNA synthetase 1
chr22_+_35381086 Show fit	6.12	ENST00000216117.9 ENST00000677931.1 ENST00000679074.1	HMOX1 Links Ensembl NCBI GeneCards UniProt Show fit	heme oxygenase 1
chr19_+_33374312 Show fit	6.04	ENST00000585933.2	CEBPG Links Ensembl NCBI GeneCards UniProt Show fit	CCAAT enhancer binding protein gamma
chr11_-_102798148 Show fit	5.98	ENST00000315274.7	MMP1 Links Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 1
chr12_-_46268989 Show fit	5.83	ENST00000549049.5 ENST00000439706.5 ENST00000398637.10	SLC38A1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 38 member 1
chr22_-_30246739 Show fit	5.83	ENST00000403987.3 ENST00000249075.4	LIF Links Ensembl NCBI GeneCards UniProt Show fit	LIF interleukin 6 family cytokine
chr4_-_154612635 Show fit	5.82	ENST00000407946.5 ENST00000405164.5 ENST00000336098.8 ENST00000393846.6 ENST00000404648.7 ENST00000443553.5	FGG Links Ensembl NCBI GeneCards UniProt Show fit	fibrinogen gamma chain
chr5_+_52787899 Show fit	5.73	ENST00000274311.3 ENST00000282588.7	PELO Links Ensembl NCBI GeneCards UniProt Show fit ITGA1 Links Ensembl NCBI GeneCards UniProt Show fit	pelota mRNA surveillance and ribosome rescue factor integrin subunit alpha 1
chr6_+_31927683 Show fit	5.69	ENST00000456570.5	ENSG00000244255.5 Links Ensembl NCBI GeneCards UniProt Show fit	novel complement component 2 (C2) and complement factor B (CFB) protein
chr5_+_179678613 Show fit	5.47	ENST00000681674.1 ENST00000681712.1 ENST00000681903.1	CANX Links Ensembl NCBI GeneCards UniProt Show fit	calnexin
chr21_-_43075831 Show fit	5.46	ENST00000398158.5 ENST00000398165.8	CBS Links Ensembl NCBI GeneCards UniProt Show fit	cystathionine beta-synthase
chr16_+_56936654 Show fit	5.38	ENST00000563911.5	HERPUD1 Links Ensembl NCBI GeneCards UniProt Show fit	homocysteine inducible ER protein with ubiquitin like domain 1
chr9_+_2621766 Show fit	5.38	ENST00000382100.8	VLDLR Links Ensembl NCBI GeneCards UniProt Show fit	very low density lipoprotein receptor
chr3_+_12351493 Show fit	5.27	ENST00000683699.1	PPARG Links Ensembl NCBI GeneCards UniProt Show fit	peroxisome proliferator activated receptor gamma
chr2_+_210556590 Show fit	5.14	ENST00000233072.10 ENST00000619804.1	CPS1 Links Ensembl NCBI GeneCards UniProt Show fit	carbamoyl-phosphate synthase 1
chr9_+_2621556 Show fit	5.08	ENST00000680746.1	VLDLR Links Ensembl NCBI GeneCards UniProt Show fit	very low density lipoprotein receptor
chr11_+_62881686 Show fit	5.03	ENST00000536981.6 ENST00000539891.6	SLC3A2 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 3 member 2
chr12_-_6342020 Show fit	4.95	ENST00000540022.5 ENST00000536194.1	TNFRSF1A Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 1A
chr17_-_40822604 Show fit	4.78	ENST00000269576.6 ENST00000635956.2	KRT10 Links Ensembl NCBI GeneCards UniProt Show fit	keratin 10
chr11_-_3057386 Show fit	4.62	ENST00000529772.5 ENST00000278224.13 ENST00000380525.9	CARS1 Links Ensembl NCBI GeneCards UniProt Show fit	cysteinyl-tRNA synthetase 1
chr21_-_6467509 Show fit	4.49	ENST00000624406.3 ENST00000398168.5 ENST00000624934.3	CBSL Links Ensembl NCBI GeneCards UniProt Show fit	cystathionine beta-synthase like
chr20_+_57561103 Show fit	4.43	ENST00000319441.6	PCK1 Links Ensembl NCBI GeneCards UniProt Show fit	phosphoenolpyruvate carboxykinase 1
chr12_+_57455266 Show fit	4.42	ENST00000266646.3	INHBE Links Ensembl NCBI GeneCards UniProt Show fit	inhibin subunit beta E
chr6_-_41941507 Show fit	4.33	ENST00000372987.8	CCND3 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin D3
chr1_-_220046432 Show fit	4.32	ENST00000609181.5 ENST00000366923.8	EPRS1 Links Ensembl NCBI GeneCards UniProt Show fit	glutamyl-prolyl-tRNA synthetase 1
chr7_-_56034133 Show fit	4.26	ENST00000421626.5	PSPH Links Ensembl NCBI GeneCards UniProt Show fit	phosphoserine phosphatase
chr3_+_12351470 Show fit	4.20	ENST00000287820.10	PPARG Links Ensembl NCBI GeneCards UniProt Show fit	peroxisome proliferator activated receptor gamma
chr16_+_72054477 Show fit	4.18	ENST00000355906.10 ENST00000570083.5 ENST00000228226.12 ENST00000398131.6 ENST00000569639.5 ENST00000564499.5 ENST00000357763.8 ENST00000613898.1 ENST00000562526.5 ENST00000565574.5 ENST00000568417.6	HP Links Ensembl NCBI GeneCards UniProt Show fit	haptoglobin
chr6_-_41941795 Show fit	4.13	ENST00000372991.9	CCND3 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin D3
chr16_+_1309714 Show fit	4.08	ENST00000566587.5	UBE2I Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 I
chr19_+_48993864 Show fit	3.98	ENST00000595090.6	RUVBL2 Links Ensembl NCBI GeneCards UniProt Show fit	RuvB like AAA ATPase 2
chr6_-_41941728 Show fit	3.86	ENST00000414200.6	CCND3 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin D3
chr15_+_96325935 Show fit	3.80	ENST00000421109.6	NR2F2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 2 group F member 2
chrX_-_107000185 Show fit	3.79	ENST00000355610.9	MORC4 Links Ensembl NCBI GeneCards UniProt Show fit	MORC family CW-type zinc finger 4
chr12_-_6342066 Show fit	3.78	ENST00000162749.7 ENST00000440083.6	TNFRSF1A Links Ensembl NCBI GeneCards UniProt Show fit	TNF receptor superfamily member 1A
chr5_+_126423176 Show fit	3.77	ENST00000542322.5 ENST00000544396.5	GRAMD2B Links Ensembl NCBI GeneCards UniProt Show fit	GRAM domain containing 2B
chr14_-_91946989 Show fit	3.65	ENST00000556154.5	FBLN5 Links Ensembl NCBI GeneCards UniProt Show fit	fibulin 5
chrX_-_134658450 Show fit	3.64	ENST00000359237.9	PLAC1 Links Ensembl NCBI GeneCards UniProt Show fit	placenta enriched 1
chr3_-_64019334 Show fit	3.63	ENST00000480205.5	PSMD6 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome 26S subunit, non-ATPase 6
chr11_+_119085200 Show fit	3.61	ENST00000650101.1	HMBS Links Ensembl NCBI GeneCards UniProt Show fit	hydroxymethylbilane synthase
chr2_+_71453538 Show fit	3.60	ENST00000258104.8	DYSF Links Ensembl NCBI GeneCards UniProt Show fit	dysferlin
chr20_-_34112205 Show fit	3.55	ENST00000374980.3	EIF2S2 Links Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 2 subunit beta
chr5_+_126423122 Show fit	3.54	ENST00000515200.5	GRAMD2B Links Ensembl NCBI GeneCards UniProt Show fit	GRAM domain containing 2B
chr2_-_159798234 Show fit	3.46	ENST00000429078.6 ENST00000553424.5	CD302 Links Ensembl NCBI GeneCards UniProt Show fit	CD302 molecule
chr5_+_126423363 Show fit	3.46	ENST00000285689.8	GRAMD2B Links Ensembl NCBI GeneCards UniProt Show fit	GRAM domain containing 2B
chr6_+_32844789 Show fit	3.44	ENST00000414474.5	PSMB9 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit beta 9
chr11_-_31810991 Show fit	3.36	ENST00000640684.1	PAX6 Links Ensembl NCBI GeneCards UniProt Show fit	paired box 6
chr7_+_99408609 Show fit	3.32	ENST00000403633.6	BUD31 Links Ensembl NCBI GeneCards UniProt Show fit	BUD31 homolog
chr11_+_119084873 Show fit	3.31	ENST00000652429.1 ENST00000442944.7 ENST00000537841.5 ENST00000542729.5 ENST00000546302.6 ENST00000536813.6 ENST00000544387.5 ENST00000543090.5	HMBS Links Ensembl NCBI GeneCards UniProt Show fit	hydroxymethylbilane synthase
chr19_+_35745613 Show fit	3.28	ENST00000222266.2 ENST00000587708.7	PSENEN Links Ensembl NCBI GeneCards UniProt Show fit	presenilin enhancer, gamma-secretase subunit
chr19_+_35745590 Show fit	3.27	ENST00000591949.1	PSENEN Links Ensembl NCBI GeneCards UniProt Show fit	presenilin enhancer, gamma-secretase subunit
chr5_-_132777866 Show fit	3.11	ENST00000448933.5	SEPTIN8 Links Ensembl NCBI GeneCards UniProt Show fit	septin 8
chr10_+_113125536 Show fit	3.05	ENST00000349937.7	TCF7L2 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 7 like 2
chr1_-_149936324 Show fit	3.05	ENST00000369140.7	MTMR11 Links Ensembl NCBI GeneCards UniProt Show fit	myotubularin related protein 11
chr3_-_187745460 Show fit	2.97	ENST00000406870.7	BCL6 Links Ensembl NCBI GeneCards UniProt Show fit	BCL6 transcription repressor
chr2_-_159798043 Show fit	2.92	ENST00000664982.1 ENST00000259053.6	ENSG00000287091.1 Links Ensembl NCBI GeneCards UniProt Show fit CD302 Links Ensembl NCBI GeneCards UniProt Show fit	novel transcript, sense intronic to CD302and LY75-CD302 CD302 molecule
chr16_-_70289480 Show fit	2.86	ENST00000261772.13 ENST00000675953.1 ENST00000675691.1 ENST00000675133.1 ENST00000674512.1 ENST00000675045.1 ENST00000675853.1 ENST00000565361.3 ENST00000674963.1 ENST00000674691.1	AARS1 Links Ensembl NCBI GeneCards UniProt Show fit	alanyl-tRNA synthetase 1
chr6_+_31927703 Show fit	2.82	ENST00000418949.6 ENST00000299367.10 ENST00000383177.7 ENST00000477310.1	C2 Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000244255.5 Links Ensembl NCBI GeneCards UniProt Show fit	complement C2 novel complement component 2 (C2) and complement factor B (CFB) protein
chr1_-_27626229 Show fit	2.57	ENST00000399173.5	FGR Links Ensembl NCBI GeneCards UniProt Show fit	FGR proto-oncogene, Src family tyrosine kinase
chr16_+_56932134 Show fit	2.57	ENST00000439977.7 ENST00000300302.9 ENST00000344114.8 ENST00000379792.6	HERPUD1 Links Ensembl NCBI GeneCards UniProt Show fit	homocysteine inducible ER protein with ubiquitin like domain 1
chr12_-_24949026 Show fit	2.56	ENST00000539780.5 ENST00000546285.1 ENST00000342945.9 ENST00000261192.12	BCAT1 Links Ensembl NCBI GeneCards UniProt Show fit	branched chain amino acid transaminase 1
chr12_-_122703346 Show fit	2.53	ENST00000328880.6	HCAR2 Links Ensembl NCBI GeneCards UniProt Show fit	hydroxycarboxylic acid receptor 2
chr6_-_158819355 Show fit	2.52	ENST00000367075.4	EZR Links Ensembl NCBI GeneCards UniProt Show fit	ezrin
chr2_+_240868817 Show fit	2.40	ENST00000307503.4	AGXT Links Ensembl NCBI GeneCards UniProt Show fit	alanine--glyoxylate and serine--pyruvate aminotransferase
chr12_+_111405861 Show fit	2.33	ENST00000341259.7	SH2B3 Links Ensembl NCBI GeneCards UniProt Show fit	SH2B adaptor protein 3
chr4_-_163613505 Show fit	2.31	ENST00000339875.9	MARCHF1 Links Ensembl NCBI GeneCards UniProt Show fit	membrane associated ring-CH-type finger 1
chr5_-_142325001 Show fit	2.28	ENST00000344120.4 ENST00000434127.3	SPRY4 Links Ensembl NCBI GeneCards UniProt Show fit	sprouty RTK signaling antagonist 4
chr12_-_54297884 Show fit	2.27	ENST00000553198.1	NFE2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear factor, erythroid 2
chr5_+_38846002 Show fit	2.26	ENST00000274276.8	OSMR Links Ensembl NCBI GeneCards UniProt Show fit	oncostatin M receptor
chr5_+_150640652 Show fit	2.18	ENST00000307662.5	SYNPO Links Ensembl NCBI GeneCards UniProt Show fit	synaptopodin
chr1_-_149936816 Show fit	2.14	ENST00000439741.4	MTMR11 Links Ensembl NCBI GeneCards UniProt Show fit	myotubularin related protein 11
chr20_+_38346474 Show fit	1.97	ENST00000217407.3	LBP Links Ensembl NCBI GeneCards UniProt Show fit	lipopolysaccharide binding protein
chr12_-_122716790 Show fit	1.97	ENST00000528880.3	HCAR3 Links Ensembl NCBI GeneCards UniProt Show fit	hydroxycarboxylic acid receptor 3
chr7_+_80133830 Show fit	1.96	ENST00000648098.1 ENST00000648476.1 ENST00000648412.1 ENST00000648953.1 ENST00000648306.1 ENST00000648832.1 ENST00000648877.1 ENST00000442586.2 ENST00000649487.1 ENST00000649267.1	GNAI1 Links Ensembl NCBI GeneCards UniProt Show fit	G protein subunit alpha i1
chr1_+_154272589 Show fit	1.93	ENST00000457918.6 ENST00000483970.6 ENST00000328703.12 ENST00000435087.1 ENST00000532105.1	HAX1 Links Ensembl NCBI GeneCards UniProt Show fit	HCLS1 associated protein X-1
chr1_+_218345326 Show fit	1.84	ENST00000366930.9	TGFB2 Links Ensembl NCBI GeneCards UniProt Show fit	transforming growth factor beta 2
chr11_-_31811231 Show fit	1.76	ENST00000438681.6	PAX6 Links Ensembl NCBI GeneCards UniProt Show fit	paired box 6
chr2_+_28395511 Show fit	1.76	ENST00000436647.1	FOSL2 Links Ensembl NCBI GeneCards UniProt Show fit	FOS like 2, AP-1 transcription factor subunit
chr1_+_153259684 Show fit	1.72	ENST00000368742.4	LORICRIN Links Ensembl NCBI GeneCards UniProt Show fit	loricrin cornified envelope precursor protein
chr17_-_79839387 Show fit	1.70	ENST00000448310.1 ENST00000269397.9	CBX4 Links Ensembl NCBI GeneCards UniProt Show fit	chromobox 4
chr4_-_69860138 Show fit	1.68	ENST00000226444.4	SULT1E1 Links Ensembl NCBI GeneCards UniProt Show fit	sulfotransferase family 1E member 1
chr1_-_44031446 Show fit	1.64	ENST00000372310.8 ENST00000466926.1	SLC6A9 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 6 member 9
chr11_-_31811112 Show fit	1.60	ENST00000640242.1 ENST00000640613.1 ENST00000606377.7	PAX6 Links Ensembl NCBI GeneCards UniProt Show fit	paired box 6
chr7_+_28685968 Show fit	1.56	ENST00000396298.6	CREB5 Links Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element binding protein 5
chr17_-_48626325 Show fit	1.49	ENST00000311177.7	HOXB9 Links Ensembl NCBI GeneCards UniProt Show fit	homeobox B9
chr5_-_102296260 Show fit	1.47	ENST00000310954.7	SLCO4C1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier organic anion transporter family member 4C1
chr3_+_186717348 Show fit	1.47	ENST00000447445.1 ENST00000287611.8 ENST00000644859.2	KNG1 Links Ensembl NCBI GeneCards UniProt Show fit	kininogen 1
chr7_+_114922346 Show fit	1.47	ENST00000393486.5	MDFIC Links Ensembl NCBI GeneCards UniProt Show fit	MyoD family inhibitor domain containing
chr18_+_63752935 Show fit	1.46	ENST00000425392.5 ENST00000336429.6	SERPINB7 Links Ensembl NCBI GeneCards UniProt Show fit	serpin family B member 7
chr5_+_170353480 Show fit	1.39	ENST00000377360.8	KCNIP1 Links Ensembl NCBI GeneCards UniProt Show fit	potassium voltage-gated channel interacting protein 1
chr6_+_31927486 Show fit	1.38	ENST00000442278.6	C2 Links Ensembl NCBI GeneCards UniProt Show fit	complement C2
chr16_-_28539004 Show fit	1.34	ENST00000395641.2	NUPR1 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear protein 1, transcriptional regulator
chr19_-_54313074 Show fit	1.34	ENST00000486742.2 ENST00000432233.8	LILRA5 Links Ensembl NCBI GeneCards UniProt Show fit	leukocyte immunoglobulin like receptor A5
chr5_-_179620933 Show fit	1.31	ENST00000521173.5	HNRNPH1 Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein H1
chr11_-_31811140 Show fit	1.30	ENST00000639916.1	PAX6 Links Ensembl NCBI GeneCards UniProt Show fit	paired box 6
chr7_-_116030750 Show fit	1.29	ENST00000265440.12 ENST00000320239.11	TFEC Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor EC
chr10_+_14838288 Show fit	1.23	ENST00000640019.3 ENST00000493178.1 ENST00000378372.8	ENSG00000284024.4 Links Ensembl NCBI GeneCards UniProt Show fit HSPA14 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein heat shock protein family A (Hsp70) member 14
chr3_-_100114488 Show fit	1.20	ENST00000477258.2 ENST00000354552.7 ENST00000331335.9 ENST00000398326.2	FILIP1L Links Ensembl NCBI GeneCards UniProt Show fit	filamin A interacting protein 1 like
chr16_-_57775103 Show fit	1.14	ENST00000540079.6 ENST00000569222.5	KIFC3 Links Ensembl NCBI GeneCards UniProt Show fit	kinesin family member C3
chr7_-_77199808 Show fit	1.10	ENST00000248598.6	FGL2 Links Ensembl NCBI GeneCards UniProt Show fit	fibrinogen like 2
chr14_-_91947383 Show fit	1.06	ENST00000267620.14	FBLN5 Links Ensembl NCBI GeneCards UniProt Show fit	fibulin 5
chr11_-_31811034 Show fit	1.05	ENST00000638250.1	PAX6 Links Ensembl NCBI GeneCards UniProt Show fit	paired box 6
chr7_-_116030735 Show fit	1.03	ENST00000393485.5	TFEC Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor EC
chr16_-_28538951 Show fit	1.00	ENST00000324873.8	NUPR1 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear protein 1, transcriptional regulator
chrX_+_9463272 Show fit	0.97	ENST00000407597.7 ENST00000380961.5 ENST00000424279.6	TBL1X Links Ensembl NCBI GeneCards UniProt Show fit	transducin beta like 1 X-linked
chr17_-_43125353 Show fit	0.94	ENST00000476777.5 ENST00000491747.6 ENST00000478531.5 ENST00000357654.9 ENST00000477152.5 ENST00000618469.1 ENST00000352993.7 ENST00000493795.5 ENST00000493919.5	BRCA1 Links Ensembl NCBI GeneCards UniProt Show fit	BRCA1 DNA repair associated
chr5_-_82278341 Show fit	0.94	ENST00000510210.5 ENST00000512493.5 ENST00000296674.13 ENST00000507980.1 ENST00000511844.1 ENST00000651545.1	RPS23 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S23
chr12_-_95996302 Show fit	0.91	ENST00000261208.8 ENST00000538703.5 ENST00000541929.5	HAL Links Ensembl NCBI GeneCards UniProt Show fit	histidine ammonia-lyase
chr1_-_44031352 Show fit	0.80	ENST00000372306.7 ENST00000475075.6	SLC6A9 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 6 member 9
chr7_-_99408548 Show fit	0.80	ENST00000626285.1 ENST00000350498.8	PDAP1 Links Ensembl NCBI GeneCards UniProt Show fit	PDGFA associated protein 1
chr12_+_6535278 Show fit	0.78	ENST00000396858.5	GAPDH Links Ensembl NCBI GeneCards UniProt Show fit	glyceraldehyde-3-phosphate dehydrogenase
chr1_+_99646025 Show fit	0.77	ENST00000263174.9 ENST00000605497.5 ENST00000615664.1	PALMD Links Ensembl NCBI GeneCards UniProt Show fit	palmdelphin
chr2_+_46542474 Show fit	0.76	ENST00000238738.9	RHOQ Links Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member Q
chr17_-_43125300 Show fit	0.73	ENST00000497488.1 ENST00000354071.7 ENST00000489037.1 ENST00000470026.5 ENST00000644555.1 ENST00000586385.5 ENST00000591534.5 ENST00000591849.5	BRCA1 Links Ensembl NCBI GeneCards UniProt Show fit	BRCA1 DNA repair associated
chr17_+_58148384 Show fit	0.72	ENST00000268912.6 ENST00000641449.1	OR4D1 Links Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 4 subfamily D member 1
chr11_-_31810657 Show fit	0.71	ENST00000379109.7	PAX6 Links Ensembl NCBI GeneCards UniProt Show fit	paired box 6
chrX_+_13569593 Show fit	0.71	ENST00000361306.6 ENST00000380602.3	EGFL6 Links Ensembl NCBI GeneCards UniProt Show fit	EGF like domain multiple 6
chrX_+_100584928 Show fit	0.69	ENST00000373031.5	TNMD Links Ensembl NCBI GeneCards UniProt Show fit	tenomodulin
chr1_-_221742074 Show fit	0.67	ENST00000366899.4	DUSP10 Links Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 10
chr17_-_43125450 Show fit	0.66	ENST00000494123.5 ENST00000468300.5 ENST00000471181.7 ENST00000652672.1	BRCA1 Links Ensembl NCBI GeneCards UniProt Show fit	BRCA1 DNA repair associated
chr17_-_10469558 Show fit	0.60	ENST00000255381.2	MYH4 Links Ensembl NCBI GeneCards UniProt Show fit	myosin heavy chain 4
chr15_-_79971164 Show fit	0.59	ENST00000335661.6 ENST00000267953.4 ENST00000677151.1	BCL2A1 Links Ensembl NCBI GeneCards UniProt Show fit	BCL2 related protein A1
chr6_+_31971831 Show fit	0.58	ENST00000375331.7 ENST00000375333.3	STK19 Links Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 19
chrX_+_116436599 Show fit	0.58	ENST00000598581.3	SLC6A14 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 6 member 14
chr8_-_42501224 Show fit	0.58	ENST00000520262.6 ENST00000517366.1	SLC20A2 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 20 member 2
chr7_-_27185223 Show fit	0.49	ENST00000517402.1 ENST00000006015.4	HOXA11 Links Ensembl NCBI GeneCards UniProt Show fit	homeobox A11
chr9_-_13175824 Show fit	0.45	ENST00000545857.5	MPDZ Links Ensembl NCBI GeneCards UniProt Show fit	multiple PDZ domain crumbs cell polarity complex component
chr10_-_35090545 Show fit	0.43	ENST00000374751.7 ENST00000626172.2	CUL2 Links Ensembl NCBI GeneCards UniProt Show fit	cullin 2
chr3_+_45689338 Show fit	0.42	ENST00000438671.3 ENST00000389061.10	SACM1L Links Ensembl NCBI GeneCards UniProt Show fit	SAC1 like phosphatidylinositide phosphatase
chr11_+_7485492 Show fit	0.42	ENST00000534244.1 ENST00000329293.4	OLFML1 Links Ensembl NCBI GeneCards UniProt Show fit	olfactomedin like 1
chr3_+_45689241 Show fit	0.40	ENST00000418611.5 ENST00000672477.1	SACM1L Links Ensembl NCBI GeneCards UniProt Show fit	SAC1 like phosphatidylinositide phosphatase
chr15_+_40953463 Show fit	0.36	ENST00000617768.5	CHAC1 Links Ensembl NCBI GeneCards UniProt Show fit	ChaC glutathione specific gamma-glutamylcyclotransferase 1
chr10_+_95755652 Show fit	0.35	ENST00000371207.8	ENTPD1 Links Ensembl NCBI GeneCards UniProt Show fit	ectonucleoside triphosphate diphosphohydrolase 1
chrX_-_81201886 Show fit	0.34	ENST00000451455.1 ENST00000358130.7 ENST00000436386.5	HMGN5 Links Ensembl NCBI GeneCards UniProt Show fit	high mobility group nucleosome binding domain 5
chr1_-_23531206 Show fit	0.31	ENST00000361729.3	E2F2 Links Ensembl NCBI GeneCards UniProt Show fit	E2F transcription factor 2
chr10_+_95755737 Show fit	0.30	ENST00000543964.6	ENTPD1 Links Ensembl NCBI GeneCards UniProt Show fit	ectonucleoside triphosphate diphosphohydrolase 1
chrX_-_152451273 Show fit	0.30	ENST00000370314.9	GABRA3 Links Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit alpha3
chr7_+_48924559 Show fit	0.29	ENST00000650262.1	CDC14C Links Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 14C
chr15_+_98648502 Show fit	0.29	ENST00000650285.1 ENST00000649865.1	IGF1R Links Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor 1 receptor
chr6_+_5261497 Show fit	0.26	ENST00000274680.9	FARS2 Links Ensembl NCBI GeneCards UniProt Show fit	phenylalanyl-tRNA synthetase 2, mitochondrial
chr3_-_3110347 Show fit	0.23	ENST00000383846.5 ENST00000427088.1 ENST00000446632.7 ENST00000418488.6 ENST00000438560.5	IL5RA Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 5 receptor subunit alpha
chr13_+_27251545 Show fit	0.22	ENST00000311549.11	RPL21 Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L21
chr16_+_58392462 Show fit	0.22	ENST00000318129.6	GINS3 Links Ensembl NCBI GeneCards UniProt Show fit	GINS complex subunit 3
chr19_+_11239602 Show fit	0.21	ENST00000252453.12	ANGPTL8 Links Ensembl NCBI GeneCards UniProt Show fit	angiopoietin like 8
chr11_-_102724781 Show fit	0.21	ENST00000438475.2	MMP8 Links Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 8
chr1_+_203626775 Show fit	0.17	ENST00000367218.7	ATP2B4 Links Ensembl NCBI GeneCards UniProt Show fit	ATPase plasma membrane Ca2+ transporting 4
chr17_+_30921935 Show fit	0.14	ENST00000581285.5 ENST00000330889.8	ADAP2 Links Ensembl NCBI GeneCards UniProt Show fit	ArfGAP with dual PH domains 2
chr3_-_48016400 Show fit	0.11	ENST00000434267.5 ENST00000683076.1 ENST00000633710.1	MAP4 Links Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 4
chr2_+_135586250 Show fit	0.10	ENST00000410054.5 ENST00000628915.2	R3HDM1 Links Ensembl NCBI GeneCards UniProt Show fit	R3H domain containing 1
chr12_+_55997180 Show fit	0.10	ENST00000356124.8 ENST00000266971.8 ENST00000394115.6 ENST00000547586.5 ENST00000552258.5 ENST00000548274.5 ENST00000546833.5	SUOX Links Ensembl NCBI GeneCards UniProt Show fit	sulfite oxidase
chr16_+_1309621 Show fit	0.06	ENST00000397515.6 ENST00000397514.8 ENST00000567383.6 ENST00000403747.6	UBE2I Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 I
chr1_+_87328860 Show fit	0.05	ENST00000370544.10	LMO4 Links Ensembl NCBI GeneCards UniProt Show fit	LIM domain only 4

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.3	61.9	GO:0019264	glycine biosynthetic process from serine(GO:0019264)
4.1	16.5	GO:1903803	glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
3.4	10.3	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
2.7	21.4	GO:0055129	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
2.7	8.0	GO:1903015	regulation of exo-alpha-sialidase activity(GO:1903015)
2.3	6.9	GO:0018160	peptidyl-pyrromethane cofactor linkage(GO:0018160)
2.3	9.1	GO:0032764	negative regulation of mast cell cytokine production(GO:0032764)
2.0	9.9	GO:0006535	cysteine biosynthetic process from serine(GO:0006535)
1.9	5.8	GO:1901674	histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
1.7	5.1	GO:0071400	carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) cellular response to oleic acid(GO:0071400) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
1.5	10.5	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
1.5	4.4	GO:0051365	cellular response to potassium ion starvation(GO:0051365)
1.4	4.2	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
1.4	9.5	GO:2000230	negative regulation of pancreatic stellate cell proliferation(GO:2000230)
1.2	2.4	GO:0019448	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
1.2	7.1	GO:0032383	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
1.1	5.7	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
1.1	7.7	GO:0009048	dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
1.0	22.8	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
1.0	4.1	GO:1903755	regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
1.0	4.0	GO:0071733	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.9	3.8	GO:0009956	radial pattern formation(GO:0009956)
0.8	5.0	GO:0060356	leucine import(GO:0060356)
0.8	2.4	GO:0061537	glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.7	7.0	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.7	6.7	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.7	2.6	GO:0002536	respiratory burst involved in inflammatory response(GO:0002536) regulation of respiratory burst involved in inflammatory response(GO:0060264)
0.6	1.8	GO:0042704	uterine wall breakdown(GO:0042704)
0.6	6.0	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.6	8.7	GO:0071550	death-inducing signaling complex assembly(GO:0071550)
0.6	9.8	GO:0003322	pancreatic A cell development(GO:0003322)
0.6	1.7	GO:0006711	estrogen catabolic process(GO:0006711)
0.6	6.7	GO:0006449	regulation of translational termination(GO:0006449)
0.6	3.3	GO:2000825	positive regulation of androgen receptor activity(GO:2000825)
0.5	2.6	GO:0009099	branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.5	8.6	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.5	2.5	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.5	2.5	GO:1902896	terminal web assembly(GO:1902896)
0.5	8.0	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.5	4.3	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.5	2.3	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.4	3.5	GO:0002176	male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.4	11.5	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.4	4.7	GO:0048251	elastic fiber assembly(GO:0048251)
0.4	6.5	GO:0007220	Notch receptor processing(GO:0007220)
0.4	4.2	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.4	1.5	GO:0090362	positive regulation of platelet-derived growth factor production(GO:0090362)
0.3	5.8	GO:1902475	L-alpha-amino acid transmembrane transport(GO:1902475)
0.3	6.5	GO:0097186	amelogenesis(GO:0097186)
0.3	0.9	GO:0043606	histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.3	5.5	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.3	12.3	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.3	1.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.3	3.6	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.3	5.8	GO:0090331	negative regulation of platelet aggregation(GO:0090331)
0.3	3.1	GO:0044334	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) myoblast fate commitment(GO:0048625) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.2	2.2	GO:0099563	modification of synaptic structure(GO:0099563)
0.2	3.6	GO:0001778	plasma membrane repair(GO:0001778)
0.2	0.8	GO:0035606	peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2	2.0	GO:1904321	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1	6.0	GO:0032461	positive regulation of protein oligomerization(GO:0032461)
0.1	0.7	GO:0035990	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1	12.9	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.1	2.3	GO:2000194	regulation of female gonad development(GO:2000194)
0.1	2.6	GO:0033008	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.1	1.9	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.1	0.3	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.1	1.8	GO:0003334	keratinocyte development(GO:0003334)
0.1	6.9	GO:0042267	natural killer cell mediated cytotoxicity(GO:0042267)
0.1	2.3	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.1	4.4	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.1	2.3	GO:0006337	nucleosome disassembly(GO:0006337)
0.1	0.6	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.1	1.5	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.1	2.9	GO:0018149	peptide cross-linking(GO:0018149)
0.1	0.3	GO:0051389	inactivation of MAPKK activity(GO:0051389)
0.1	0.3	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.5	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
0.0	1.5	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.8	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0	0.9	GO:0018126	protein hydroxylation(GO:0018126)
0.0	2.3	GO:0070373	negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0	0.4	GO:0006751	glutathione catabolic process(GO:0006751)
0.0	0.1	GO:0070221	sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0	0.3	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.0	0.6	GO:0008053	mitochondrial fusion(GO:0008053)
0.0	1.5	GO:1904590	negative regulation of protein import into nucleus(GO:0042308) negative regulation of protein import(GO:1904590)
0.0	6.4	GO:0006909	phagocytosis(GO:0006909)
0.0	0.2	GO:0050746	regulation of lipoprotein metabolic process(GO:0050746)
0.0	7.0	GO:0006897	endocytosis(GO:0006897)
0.0	1.7	GO:0016925	protein sumoylation(GO:0016925)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.2	61.9	GO:0070552	BRISC complex(GO:0070552)
3.2	9.5	GO:1990622	CHOP-ATF3 complex(GO:1990622)
2.6	10.3	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
1.5	10.2	GO:1990111	spermatoproteasome complex(GO:1990111)
1.4	5.7	GO:0034665	integrin alpha1-beta1 complex(GO:0034665)
1.1	8.0	GO:1990037	Lewy body core(GO:1990037)
1.0	4.2	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
1.0	4.1	GO:1990356	sumoylated E2 ligase complex(GO:1990356)
0.8	2.5	GO:0044393	microspike(GO:0044393)
0.7	6.5	GO:0070765	gamma-secretase complex(GO:0070765)
0.6	4.7	GO:0071953	elastic fiber(GO:0071953)
0.6	6.9	GO:0005577	fibrinogen complex(GO:0005577)
0.5	17.2	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.5	2.3	GO:0031436	BRCA1-BARD1 complex(GO:0031436)
0.4	4.0	GO:0097255	R2TP complex(GO:0097255)
0.4	7.3	GO:0005641	nuclear envelope lumen(GO:0005641)
0.3	5.5	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.3	7.0	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.3	3.1	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.2	12.3	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2	9.5	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.1	10.8	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.1	3.6	GO:0005838	proteasome regulatory particle(GO:0005838)
0.1	11.5	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	5.1	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1	1.7	GO:0035102	PRC1 complex(GO:0035102)
0.1	1.1	GO:0005915	zonula adherens(GO:0005915)
0.1	0.8	GO:0097452	GAIT complex(GO:0097452)
0.1	14.1	GO:0048770	melanosome(GO:0042470) pigment granule(GO:0048770)
0.1	5.5	GO:0005902	microvillus(GO:0005902)
0.1	11.3	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.1	2.5	GO:0001533	cornified envelope(GO:0001533)
0.1	2.6	GO:0016235	aggresome(GO:0016235)
0.1	0.4	GO:0030891	VCB complex(GO:0030891)
0.0	5.2	GO:0005901	caveola(GO:0005901)
0.0	0.3	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	21.8	GO:0005759	mitochondrial matrix(GO:0005759)
0.0	3.0	GO:0005657	replication fork(GO:0005657)
0.0	3.3	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.0	12.4	GO:0019898	extrinsic component of membrane(GO:0019898)
0.0	0.8	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	1.5	GO:0035577	azurophil granule membrane(GO:0035577)
0.0	0.4	GO:0043220	Schmidt-Lanterman incisure(GO:0043220)
0.0	9.8	GO:0000790	nuclear chromatin(GO:0000790)
0.0	1.9	GO:0016529	sarcoplasmic reticulum(GO:0016529)
0.0	0.6	GO:0032982	myosin filament(GO:0032982)
0.0	1.4	GO:1904724	tertiary granule lumen(GO:1904724)
0.0	2.9	GO:0043197	dendritic spine(GO:0043197)
0.0	1.0	GO:0005876	spindle microtubule(GO:0005876)
0.0	2.3	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.8	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.0	2.9	GO:0030027	lamellipodium(GO:0030027)
0.0	0.9	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	1.3	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	20.6	GO:0005887	integral component of plasma membrane(GO:0005887)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
10.3	61.9	GO:0004372	glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
3.6	21.4	GO:0004735	pyrroline-5-carboxylate reductase activity(GO:0004735)
3.5	10.5	GO:0034189	very-low-density lipoprotein particle binding(GO:0034189)
2.8	13.9	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
2.4	7.1	GO:0070538	oleic acid binding(GO:0070538)
2.3	6.9	GO:0004418	hydroxymethylbilane synthase activity(GO:0004418)
2.0	9.9	GO:0004122	cystathionine beta-synthase activity(GO:0004122)
1.9	15.1	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
1.7	6.7	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
1.5	4.4	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
1.5	8.7	GO:0043120	tumor necrosis factor binding(GO:0043120)
1.3	5.1	GO:0004088	carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
1.3	20.5	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
1.2	6.1	GO:0004392	heme oxygenase (decyclizing) activity(GO:0004392)
1.1	8.0	GO:0001849	complement component C1q binding(GO:0001849)
1.1	4.3	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
1.0	4.1	GO:0061656	SUMO conjugating enzyme activity(GO:0061656)
1.0	6.7	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.9	9.5	GO:0050692	DBD domain binding(GO:0050692)
0.8	4.0	GO:0043141	ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.7	5.7	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.6	4.2	GO:0030492	hemoglobin binding(GO:0030492)
0.6	2.3	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.5	5.8	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.5	2.6	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.5	2.6	GO:0004084	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.4	5.0	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.4	1.8	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.4	7.0	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.4	10.2	GO:0070003	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3	9.3	GO:0032794	GTPase activating protein binding(GO:0032794)
0.3	2.0	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.3	1.7	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.3	0.8	GO:0035605	peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.3	0.8	GO:0032427	GBD domain binding(GO:0032427)
0.2	17.9	GO:0003743	translation initiation factor activity(GO:0003743)
0.2	2.9	GO:0030280	structural constituent of epidermis(GO:0030280)
0.2	5.5	GO:0034185	apolipoprotein binding(GO:0034185)
0.2	5.8	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.2	12.3	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.2	3.0	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2	0.9	GO:0016841	ammonia-lyase activity(GO:0016841)
0.2	6.0	GO:0008301	DNA binding, bending(GO:0008301)
0.2	9.8	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.2	3.1	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.1	0.3	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
0.1	0.8	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1	0.6	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.1	3.8	GO:0001972	retinoic acid binding(GO:0001972)
0.1	2.5	GO:0044548	S100 protein binding(GO:0044548)
0.1	1.9	GO:0008483	transaminase activity(GO:0008483)
0.1	1.7	GO:0019789	SUMO transferase activity(GO:0019789)
0.1	1.5	GO:0030332	cyclin binding(GO:0030332)
0.1	1.1	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1	7.4	GO:0008170	N-methyltransferase activity(GO:0008170)
0.1	3.6	GO:0005544	calcium-dependent phospholipid binding(GO:0005544)
0.1	0.7	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.1	0.3	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	1.5	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	2.3	GO:0050699	WW domain binding(GO:0050699)
0.0	0.6	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	1.3	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.6	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	12.8	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	4.6	GO:0005179	hormone activity(GO:0005179)
0.0	0.4	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.0	0.6	GO:0051400	BH domain binding(GO:0051400)
0.0	4.1	GO:0005178	integrin binding(GO:0005178)
0.0	0.1	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.0	6.4	GO:0030246	carbohydrate binding(GO:0030246)
0.0	0.3	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	1.5	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	4.9	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.0	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.6	GO:0000146	microfilament motor activity(GO:0000146)
0.0	1.7	GO:0019955	cytokine binding(GO:0019955)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	15.4	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3	10.6	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.3	17.5	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3	6.5	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.2	14.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.2	5.7	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.2	12.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.2	10.0	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2	11.7	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.2	4.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	7.0	PID AURORA A PATHWAY	Aurora A signaling
0.1	1.6	ST G ALPHA S PATHWAY	G alpha s Pathway
0.1	2.6	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.1	9.8	PID CDC42 PATHWAY	CDC42 signaling events
0.1	2.3	PID EPO PATHWAY	EPO signaling pathway
0.1	3.0	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	4.4	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	3.8	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	3.1	PID AP1 PATHWAY	AP-1 transcription factor network
0.1	2.5	PID RHOA PATHWAY	RhoA signaling pathway
0.1	2.0	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	1.5	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.3	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	3.3	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
0.0	0.4	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0	1.4	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.8	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.6	PID BCR 5PATHWAY	BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.7	20.5	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.9	25.1	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.7	37.1	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.5	17.4	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.5	6.5	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
0.4	13.0	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.4	7.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.4	4.4	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.4	5.5	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.3	5.8	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.3	4.4	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.3	8.7	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.3	9.8	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2	5.7	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.2	4.2	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.2	4.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2	24.4	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.2	13.8	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.2	5.6	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	11.2	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1	2.4	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1	6.5	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.1	10.3	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.1	4.0	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.1	2.0	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
0.1	2.6	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	2.6	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	2.3	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	7.3	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.1	1.5	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	8.5	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.1	1.5	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.1	2.5	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	6.1	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.8	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	1.1	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.3	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.0	0.3	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	1.8	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.4	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	1.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production