avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Download the whole report

Gene Symbol	Gene ID	Gene Info
CEBPE Links Ensembl NCBI GeneCards UniProt	ENSG00000092067.6	CEBPE
CEBPD Links Ensembl NCBI GeneCards UniProt	ENSG00000221869.5	CEBPD

Gene	Promoter	Pearson corr. coef.	P-value	Plot
CEBPD	hg38_v1_chr8_-_47738153_47738173	0.41	4.8e-10	Click!
CEBPE	hg38_v1_chr14_-_23119248_23119265	-0.12	8.4e-02	Click!

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Promoter	Score	Transcript	Gene	Gene Info
chr9_-_91423819 Show fit	42.01	ENST00000297689.4	NFIL3 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear factor, interleukin 3 regulated
chr5_+_96662214 Show fit	34.61	ENST00000395812.6	CAST Links Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr5_+_96662366 Show fit	33.15	ENST00000675179.1 ENST00000421689.6 ENST00000674984.1 ENST00000512620.5	CAST Links Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr16_-_84618041 Show fit	32.75	ENST00000564057.1	COTL1 Links Ensembl NCBI GeneCards UniProt Show fit	coactosin like F-actin binding protein 1
chr5_+_96662314 Show fit	32.63	ENST00000674702.1	CAST Links Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr16_-_84618067 Show fit	32.30	ENST00000262428.5	COTL1 Links Ensembl NCBI GeneCards UniProt Show fit	coactosin like F-actin binding protein 1
chr15_+_45635017 Show fit	31.49	ENST00000260324.12	SQOR Links Ensembl NCBI GeneCards UniProt Show fit	sulfide quinone oxidoreductase
chr5_+_96662046 Show fit	28.59	ENST00000338252.7 ENST00000508830.5	CAST Links Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr3_+_157436842 Show fit	27.54	ENST00000295927.4	PTX3 Links Ensembl NCBI GeneCards UniProt Show fit	pentraxin 3
chr19_-_40465760 Show fit	27.33	ENST00000643519.1	BLVRB Links Ensembl NCBI GeneCards UniProt Show fit	biliverdin reductase B
chr19_-_40465736 Show fit	26.11	ENST00000263368.9 ENST00000595483.5	BLVRB Links Ensembl NCBI GeneCards UniProt Show fit	biliverdin reductase B
chr14_+_20469399 Show fit	22.32	ENST00000361505.10 ENST00000553591.1	PNP Links Ensembl NCBI GeneCards UniProt Show fit	purine nucleoside phosphorylase
chr6_-_85644043 Show fit	21.35	ENST00000678930.1 ENST00000678355.1	SYNCRIP Links Ensembl NCBI GeneCards UniProt Show fit	synaptotagmin binding cytoplasmic RNA interacting protein
chr14_-_22815421 Show fit	19.76	ENST00000674313.1 ENST00000555959.1	SLC7A7 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 7 member 7
chr1_-_156751654 Show fit	19.04	ENST00000357325.10	HDGF Links Ensembl NCBI GeneCards UniProt Show fit	heparin binding growth factor
chr14_+_103121457 Show fit	18.74	ENST00000333007.8	TNFAIP2 Links Ensembl NCBI GeneCards UniProt Show fit	TNF alpha induced protein 2
chr1_-_156751597 Show fit	18.60	ENST00000537739.5	HDGF Links Ensembl NCBI GeneCards UniProt Show fit	heparin binding growth factor
chr2_-_112836702 Show fit	18.27	ENST00000416750.1 ENST00000263341.7 ENST00000418817.5	IL1B Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 beta
chr10_+_17228215 Show fit	17.29	ENST00000544301.7	VIM Links Ensembl NCBI GeneCards UniProt Show fit	vimentin
chr4_-_184826030 Show fit	17.12	ENST00000507295.5 ENST00000504900.5 ENST00000454703.6	ACSL1 Links Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase long chain family member 1
chr15_+_58138368 Show fit	17.10	ENST00000219919.9 ENST00000536493.1	AQP9 Links Ensembl NCBI GeneCards UniProt Show fit	aquaporin 9
chr4_-_184825960 Show fit	17.01	ENST00000281455.7	ACSL1 Links Ensembl NCBI GeneCards UniProt Show fit	acyl-CoA synthetase long chain family member 1
chr19_-_2042066 Show fit	16.69	ENST00000591588.1 ENST00000591142.5	MKNK2 Links Ensembl NCBI GeneCards UniProt Show fit	MAPK interacting serine/threonine kinase 2
chr12_-_122716790 Show fit	16.10	ENST00000528880.3	HCAR3 Links Ensembl NCBI GeneCards UniProt Show fit	hydroxycarboxylic acid receptor 3
chr6_-_85643832 Show fit	16.03	ENST00000677771.1 ENST00000676688.1	SYNCRIP Links Ensembl NCBI GeneCards UniProt Show fit	synaptotagmin binding cytoplasmic RNA interacting protein
chr12_-_122703346 Show fit	15.79	ENST00000328880.6	HCAR2 Links Ensembl NCBI GeneCards UniProt Show fit	hydroxycarboxylic acid receptor 2
chr17_-_36090133 Show fit	15.73	ENST00000613922.2	CCL3 Links Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 3
chr14_-_22815801 Show fit	14.94	ENST00000397532.9	SLC7A7 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 7 member 7
chr2_-_177263522 Show fit	14.79	ENST00000448782.5 ENST00000446151.6	NFE2L2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear factor, erythroid 2 like 2
chr6_-_85643778 Show fit	14.37	ENST00000676637.1 ENST00000678528.1	SYNCRIP Links Ensembl NCBI GeneCards UniProt Show fit	synaptotagmin binding cytoplasmic RNA interacting protein
chr1_-_1779976 Show fit	13.94	ENST00000378625.5	NADK Links Ensembl NCBI GeneCards UniProt Show fit	NAD kinase
chr14_-_22815856 Show fit	13.90	ENST00000554758.1 ENST00000397528.8	SLC7A7 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 7 member 7
chr5_-_140633167 Show fit	13.68	ENST00000302014.11	CD14 Links Ensembl NCBI GeneCards UniProt Show fit	CD14 molecule
chr19_+_859654 Show fit	13.56	ENST00000592860.2 ENST00000327726.11	CFD Links Ensembl NCBI GeneCards UniProt Show fit	complement factor D
chr11_-_105035113 Show fit	13.28	ENST00000526568.5 ENST00000531166.5 ENST00000534497.5 ENST00000527979.5 ENST00000533400.6 ENST00000528974.1 ENST00000525825.5 ENST00000353247.9 ENST00000446369.5 ENST00000436863.7	CASP1 Links Ensembl NCBI GeneCards UniProt Show fit	caspase 1
chr16_+_72054477 Show fit	12.95	ENST00000355906.10 ENST00000570083.5 ENST00000228226.12 ENST00000398131.6 ENST00000569639.5 ENST00000564499.5 ENST00000357763.8 ENST00000613898.1 ENST00000562526.5 ENST00000565574.5 ENST00000568417.6	HP Links Ensembl NCBI GeneCards UniProt Show fit	haptoglobin
chr9_+_107283256 Show fit	12.82	ENST00000358015.8	RAD23B Links Ensembl NCBI GeneCards UniProt Show fit	RAD23 homolog B, nucleotide excision repair protein
chr17_-_36196748 Show fit	12.58	ENST00000619989.1	CCL3L1 Links Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine ligand 3 like 1
chr3_+_186613052 Show fit	12.46	ENST00000411641.7 ENST00000273784.5	AHSG Links Ensembl NCBI GeneCards UniProt Show fit	alpha 2-HS glycoprotein
chr20_-_35742207 Show fit	12.07	ENST00000397370.3 ENST00000528062.7 ENST00000374038.7 ENST00000253363.11 ENST00000361162.10	RBM39 Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 39
chr12_+_103930600 Show fit	11.91	ENST00000680316.1 ENST00000679861.1	HSP90B1 Links Ensembl NCBI GeneCards UniProt Show fit	heat shock protein 90 beta family member 1
chr12_+_101877571 Show fit	11.74	ENST00000258534.13	DRAM1 Links Ensembl NCBI GeneCards UniProt Show fit	DNA damage regulated autophagy modulator 1
chr19_+_33373694 Show fit	11.48	ENST00000284000.9	CEBPG Links Ensembl NCBI GeneCards UniProt Show fit	CCAAT enhancer binding protein gamma
chr17_+_7558774 Show fit	11.33	ENST00000396545.4	TNFSF13 Links Ensembl NCBI GeneCards UniProt Show fit	TNF superfamily member 13
chr2_-_177263800 Show fit	11.12	ENST00000397063.8 ENST00000421929.5	NFE2L2 Links Ensembl NCBI GeneCards UniProt Show fit	nuclear factor, erythroid 2 like 2
chr1_+_154405326 Show fit	10.66	ENST00000368485.8	IL6R Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 6 receptor
chr5_+_50667405 Show fit	9.93	ENST00000505554.5	PARP8 Links Ensembl NCBI GeneCards UniProt Show fit	poly(ADP-ribose) polymerase family member 8
chr16_-_30445865 Show fit	9.74	ENST00000478753.5	SEPHS2 Links Ensembl NCBI GeneCards UniProt Show fit	selenophosphate synthetase 2
chr1_-_186680411 Show fit	9.69	ENST00000367468.10	PTGS2 Links Ensembl NCBI GeneCards UniProt Show fit	prostaglandin-endoperoxide synthase 2
chr6_+_31927683 Show fit	9.52	ENST00000456570.5	ENSG00000244255.5 Links Ensembl NCBI GeneCards UniProt Show fit	novel complement component 2 (C2) and complement factor B (CFB) protein
chr19_-_15332507 Show fit	9.47	ENST00000679869.1 ENST00000360016.9	BRD4 Links Ensembl NCBI GeneCards UniProt Show fit	bromodomain containing 4
chr10_-_93601228 Show fit	9.30	ENST00000371464.8	RBP4 Links Ensembl NCBI GeneCards UniProt Show fit	retinol binding protein 4
chr2_-_224497816 Show fit	9.25	ENST00000451538.1	CUL3 Links Ensembl NCBI GeneCards UniProt Show fit	cullin 3
chr17_+_7558712 Show fit	8.64	ENST00000338784.9 ENST00000625791.2	TNFSF13 Links Ensembl NCBI GeneCards UniProt Show fit	TNF superfamily member 13
chr3_+_46354072 Show fit	8.56	ENST00000445132.3 ENST00000421659.1	CCR2 Links Ensembl NCBI GeneCards UniProt Show fit	C-C motif chemokine receptor 2
chr5_-_140633690 Show fit	8.41	ENST00000512545.1 ENST00000401743.6	CD14 Links Ensembl NCBI GeneCards UniProt Show fit	CD14 molecule
chr1_+_154405193 Show fit	8.40	ENST00000622330.4 ENST00000344086.8	IL6R Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 6 receptor
chr1_-_151059561 Show fit	8.24	ENST00000357235.6 ENST00000540998.5	CDC42SE1 Links Ensembl NCBI GeneCards UniProt Show fit	CDC42 small effector 1
chr5_-_10761156 Show fit	8.07	ENST00000432074.2 ENST00000230895.11	DAP Links Ensembl NCBI GeneCards UniProt Show fit	death associated protein
chr5_+_50666917 Show fit	7.61	ENST00000514342.6	PARP8 Links Ensembl NCBI GeneCards UniProt Show fit	poly(ADP-ribose) polymerase family member 8
chr19_+_6887560 Show fit	7.60	ENST00000250572.12 ENST00000381407.9 ENST00000450315.7 ENST00000312053.9 ENST00000381404.8	ADGRE1 Links Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor E1
chr4_-_102825526 Show fit	7.59	ENST00000504211.5 ENST00000508476.5	UBE2D3 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 D3
chr17_+_7558465 Show fit	7.47	ENST00000349228.8	TNFSF13 Links Ensembl NCBI GeneCards UniProt Show fit	TNF superfamily member 13
chr17_-_63773534 Show fit	7.43	ENST00000403162.7 ENST00000582252.1 ENST00000225726.10	CCDC47 Links Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 47
chr1_+_32292067 Show fit	7.16	ENST00000373548.8 ENST00000428704.1	HDAC1 Links Ensembl NCBI GeneCards UniProt Show fit	histone deacetylase 1
chr4_-_102825767 Show fit	6.87	ENST00000505207.5 ENST00000502404.5 ENST00000507845.5	UBE2D3 Links Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 D3
chr2_-_208254232 Show fit	6.64	ENST00000415913.5 ENST00000415282.5 ENST00000446179.5	IDH1 Links Ensembl NCBI GeneCards UniProt Show fit	isocitrate dehydrogenase (NADP(+)) 1
chr12_+_7060676 Show fit	6.61	ENST00000617865.4 ENST00000402681.7 ENST00000360817.10	C1S Links Ensembl NCBI GeneCards UniProt Show fit	complement C1s
chr19_-_6720641 Show fit	6.58	ENST00000245907.11	C3 Links Ensembl NCBI GeneCards UniProt Show fit	complement C3
chr2_-_215436061 Show fit	6.42	ENST00000421182.5 ENST00000432072.6 ENST00000323926.10 ENST00000336916.8 ENST00000357867.8 ENST00000359671.5 ENST00000446046.5 ENST00000354785.11 ENST00000356005.8 ENST00000443816.5 ENST00000426059.1	FN1 Links Ensembl NCBI GeneCards UniProt Show fit	fibronectin 1
chr2_+_218382265 Show fit	6.40	ENST00000233202.11	SLC11A1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 11 member 1
chr3_+_136930469 Show fit	6.31	ENST00000469404.1 ENST00000467911.1	NCK1 Links Ensembl NCBI GeneCards UniProt Show fit	NCK adaptor protein 1
chr12_-_95996302 Show fit	6.23	ENST00000261208.8 ENST00000538703.5 ENST00000541929.5	HAL Links Ensembl NCBI GeneCards UniProt Show fit	histidine ammonia-lyase
chr3_-_58214671 Show fit	6.13	ENST00000460422.1 ENST00000483681.5	DNASE1L3 Links Ensembl NCBI GeneCards UniProt Show fit	deoxyribonuclease 1 like 3
chr2_+_102104563 Show fit	6.13	ENST00000409589.5 ENST00000409329.5	IL1R1 Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 receptor type 1
chr10_+_14838288 Show fit	5.96	ENST00000640019.3 ENST00000493178.1 ENST00000378372.8	ENSG00000284024.4 Links Ensembl NCBI GeneCards UniProt Show fit HSPA14 Links Ensembl NCBI GeneCards UniProt Show fit	novel protein heat shock protein family A (Hsp70) member 14
chr10_-_80289647 Show fit	5.84	ENST00000372213.8	MAT1A Links Ensembl NCBI GeneCards UniProt Show fit	methionine adenosyltransferase 1A
chr1_-_154627576 Show fit	5.84	ENST00000648311.1	ADAR Links Ensembl NCBI GeneCards UniProt Show fit	adenosine deaminase RNA specific
chrX_-_136880715 Show fit	5.82	ENST00000431446.7 ENST00000320676.11 ENST00000562646.5	RBMX Links Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein X-linked
chr7_+_22727147 Show fit	5.76	ENST00000426291.5 ENST00000401651.5 ENST00000258743.10 ENST00000407492.5 ENST00000401630.7 ENST00000406575.1	IL6 Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 6
chr1_+_209768597 Show fit	5.72	ENST00000487271.5 ENST00000477431.1	TRAF3IP3 Links Ensembl NCBI GeneCards UniProt Show fit	TRAF3 interacting protein 3
chr3_+_11272413 Show fit	5.67	ENST00000446450.6 ENST00000354956.9 ENST00000354449.7 ENST00000419112.5	ATG7 Links Ensembl NCBI GeneCards UniProt Show fit	autophagy related 7
chr6_+_31927703 Show fit	5.65	ENST00000418949.6 ENST00000299367.10 ENST00000383177.7 ENST00000477310.1	C2 Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000244255.5 Links Ensembl NCBI GeneCards UniProt Show fit	complement C2 novel complement component 2 (C2) and complement factor B (CFB) protein
chr5_+_50666950 Show fit	5.60	ENST00000513738.5 ENST00000503665.5 ENST00000514067.6 ENST00000503046.5	PARP8 Links Ensembl NCBI GeneCards UniProt Show fit	poly(ADP-ribose) polymerase family member 8
chr5_-_179623098 Show fit	5.53	ENST00000630639.1 ENST00000329433.10 ENST00000510411.5	HNRNPH1 Links Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein H1
chr10_-_17617235 Show fit	5.48	ENST00000466335.1	HACD1 Links Ensembl NCBI GeneCards UniProt Show fit	3-hydroxyacyl-CoA dehydratase 1
chr20_+_35172046 Show fit	5.41	ENST00000216968.5	PROCR Links Ensembl NCBI GeneCards UniProt Show fit	protein C receptor
chr17_-_7114648 Show fit	5.33	ENST00000355035.9	ASGR2 Links Ensembl NCBI GeneCards UniProt Show fit	asialoglycoprotein receptor 2
chr8_-_6877928 Show fit	5.31	ENST00000297439.4	DEFB1 Links Ensembl NCBI GeneCards UniProt Show fit	defensin beta 1
chr19_-_48993300 Show fit	5.31	ENST00000323798.8 ENST00000263276.6	GYS1 Links Ensembl NCBI GeneCards UniProt Show fit	glycogen synthase 1
chr12_-_7109176 Show fit	5.18	ENST00000545280.5 ENST00000543933.5 ENST00000545337.1 ENST00000266542.9 ENST00000544702.5	C1RL Links Ensembl NCBI GeneCards UniProt Show fit	complement C1r subcomponent like
chr16_-_21652598 Show fit	5.13	ENST00000569602.1 ENST00000268389.6	IGSF6 Links Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin superfamily member 6
chr14_+_101809855 Show fit	5.08	ENST00000557714.1 ENST00000445439.7 ENST00000334743.9 ENST00000557095.5	PPP2R5C Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 2 regulatory subunit B'gamma
chr6_+_108656346 Show fit	4.96	ENST00000540898.1	FOXO3 Links Ensembl NCBI GeneCards UniProt Show fit	forkhead box O3
chr6_+_31927486 Show fit	4.96	ENST00000442278.6	C2 Links Ensembl NCBI GeneCards UniProt Show fit	complement C2
chr3_-_46464868 Show fit	4.93	ENST00000417439.5 ENST00000231751.9 ENST00000431944.1	LTF Links Ensembl NCBI GeneCards UniProt Show fit	lactotransferrin
chr17_-_7114813 Show fit	4.86	ENST00000254850.11	ASGR2 Links Ensembl NCBI GeneCards UniProt Show fit	asialoglycoprotein receptor 2
chr6_-_132734692 Show fit	4.86	ENST00000509351.5 ENST00000417437.6 ENST00000423615.6 ENST00000427187.6 ENST00000414302.7 ENST00000367927.9 ENST00000450865.2	VNN3 Links Ensembl NCBI GeneCards UniProt Show fit	vanin 3
chr1_+_209768482 Show fit	4.69	ENST00000367023.5	TRAF3IP3 Links Ensembl NCBI GeneCards UniProt Show fit	TRAF3 interacting protein 3
chr4_-_154590735 Show fit	4.59	ENST00000403106.8 ENST00000622532.1 ENST00000651975.1	FGA Links Ensembl NCBI GeneCards UniProt Show fit	fibrinogen alpha chain
chr7_+_43764191 Show fit	4.53	ENST00000424330.1	BLVRA Links Ensembl NCBI GeneCards UniProt Show fit	biliverdin reductase A
chr7_-_36724380 Show fit	4.52	ENST00000617267.4	AOAH Links Ensembl NCBI GeneCards UniProt Show fit	acyloxyacyl hydrolase
chr15_-_63157464 Show fit	4.32	ENST00000330964.10 ENST00000635699.1 ENST00000439025.1	RPS27L Links Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S27 like
chr20_+_57561103 Show fit	4.31	ENST00000319441.6	PCK1 Links Ensembl NCBI GeneCards UniProt Show fit	phosphoenolpyruvate carboxykinase 1
chr7_+_150368189 Show fit	4.24	ENST00000519397.1 ENST00000479668.5	REPIN1 Links Ensembl NCBI GeneCards UniProt Show fit	replication initiator 1
chr1_-_154608705 Show fit	4.18	ENST00000649749.1 ENST00000648871.1	ADAR Links Ensembl NCBI GeneCards UniProt Show fit	adenosine deaminase RNA specific
chr11_-_77474041 Show fit	4.14	ENST00000278568.8	PAK1 Links Ensembl NCBI GeneCards UniProt Show fit	p21 (RAC1) activated kinase 1
chr14_-_55191534 Show fit	4.08	ENST00000395425.6 ENST00000247191.7	DLGAP5 Links Ensembl NCBI GeneCards UniProt Show fit	DLG associated protein 5
chr2_-_24328113 Show fit	4.08	ENST00000622089.4	ITSN2 Links Ensembl NCBI GeneCards UniProt Show fit	intersectin 2
chr4_-_121823843 Show fit	3.94	ENST00000274026.10	CCNA2 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin A2
chr19_+_10718047 Show fit	3.86	ENST00000585892.5 ENST00000355667.11 ENST00000389253.9 ENST00000359692.10	DNM2 Links Ensembl NCBI GeneCards UniProt Show fit	dynamin 2
chr13_-_46105009 Show fit	3.84	ENST00000439329.5 ENST00000674625.1 ENST00000181383.10	CPB2 Links Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase B2
chrX_-_106038721 Show fit	3.77	ENST00000372563.2	SERPINA7 Links Ensembl NCBI GeneCards UniProt Show fit	serpin family A member 7
chr1_+_81800368 Show fit	3.69	ENST00000674489.1 ENST00000674442.1 ENST00000674419.1 ENST00000674407.1 ENST00000674168.1 ENST00000674307.1 ENST00000674209.1 ENST00000370715.5 ENST00000370713.5 ENST00000319517.10 ENST00000627151.2 ENST00000370717.6	ADGRL2 Links Ensembl NCBI GeneCards UniProt Show fit	adhesion G protein-coupled receptor L2
chr11_-_77474087 Show fit	3.68	ENST00000356341.8	PAK1 Links Ensembl NCBI GeneCards UniProt Show fit	p21 (RAC1) activated kinase 1
chr11_-_47426216 Show fit	3.62	ENST00000530651.5 ENST00000524447.6 ENST00000531051.6 ENST00000526993.1 ENST00000602866.5	PSMC3 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome 26S subunit, ATPase 3
chr8_-_101204697 Show fit	3.58	ENST00000517844.5	ZNF706 Links Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 706
chr15_+_39581068 Show fit	3.42	ENST00000397591.2 ENST00000260356.6	THBS1 Links Ensembl NCBI GeneCards UniProt Show fit	thrombospondin 1
chr11_+_119085200 Show fit	3.34	ENST00000650101.1	HMBS Links Ensembl NCBI GeneCards UniProt Show fit	hydroxymethylbilane synthase
chr11_-_47426419 Show fit	3.33	ENST00000298852.8 ENST00000530912.5 ENST00000619920.4	PSMC3 Links Ensembl NCBI GeneCards UniProt Show fit	proteasome 26S subunit, ATPase 3
chr14_+_20955484 Show fit	3.31	ENST00000304625.3	RNASE2 Links Ensembl NCBI GeneCards UniProt Show fit	ribonuclease A family member 2
chr10_-_95656643 Show fit	3.29	ENST00000371221.3 ENST00000371224.7	ALDH18A1 Links Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 18 family member A1
chr3_+_186666003 Show fit	3.28	ENST00000232003.5	HRG Links Ensembl NCBI GeneCards UniProt Show fit	histidine rich glycoprotein
chr22_-_28711931 Show fit	3.16	ENST00000434810.5 ENST00000456369.5	CHEK2 Links Ensembl NCBI GeneCards UniProt Show fit	checkpoint kinase 2
chr10_+_88990531 Show fit	3.12	ENST00000355740.7	FAS Links Ensembl NCBI GeneCards UniProt Show fit	Fas cell surface death receptor
chr3_+_186717348 Show fit	3.06	ENST00000447445.1 ENST00000287611.8 ENST00000644859.2	KNG1 Links Ensembl NCBI GeneCards UniProt Show fit	kininogen 1
chr11_+_18266254 Show fit	3.03	ENST00000532858.5 ENST00000649195.1 ENST00000356524.9 ENST00000405158.2	SAA1 Links Ensembl NCBI GeneCards UniProt Show fit	serum amyloid A1
chr10_-_17617326 Show fit	2.86	ENST00000326961.6 ENST00000361271.8	HACD1 Links Ensembl NCBI GeneCards UniProt Show fit	3-hydroxyacyl-CoA dehydratase 1
chr15_-_82952683 Show fit	2.85	ENST00000450735.7 ENST00000304231.12	HOMER2 Links Ensembl NCBI GeneCards UniProt Show fit	homer scaffold protein 2
chr2_+_46542474 Show fit	2.78	ENST00000238738.9	RHOQ Links Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member Q
chr14_+_101809795 Show fit	2.77	ENST00000350249.7 ENST00000557621.5 ENST00000556946.1	PPP2R5C Links Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 2 regulatory subunit B'gamma
chr10_+_88990621 Show fit	2.72	ENST00000352159.8	FAS Links Ensembl NCBI GeneCards UniProt Show fit	Fas cell surface death receptor
chr14_-_45253161 Show fit	2.71	ENST00000451174.1 ENST00000310806.9	MIS18BP1 Links Ensembl NCBI GeneCards UniProt Show fit	MIS18 binding protein 1
chr9_-_14314132 Show fit	2.62	ENST00000380953.6	NFIB Links Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I B
chr1_-_111200633 Show fit	2.53	ENST00000357640.9	DENND2D Links Ensembl NCBI GeneCards UniProt Show fit	DENN domain containing 2D
chr6_+_131573219 Show fit	2.51	ENST00000356962.2 ENST00000368087.8 ENST00000673427.1 ENST00000640973.1	ARG1 Links Ensembl NCBI GeneCards UniProt Show fit	arginase 1
chr2_+_63842325 Show fit	2.51	ENST00000445915.6 ENST00000475462.5	UGP2 Links Ensembl NCBI GeneCards UniProt Show fit	UDP-glucose pyrophosphorylase 2
chr19_-_41439899 Show fit	2.50	ENST00000597457.5 ENST00000589970.5 ENST00000595425.5 ENST00000438807.7 ENST00000589102.1 ENST00000221943.14 ENST00000592922.6	DMAC2 Links Ensembl NCBI GeneCards UniProt Show fit	distal membrane arm assembly complex 2
chr12_-_85836372 Show fit	2.41	ENST00000361228.5	RASSF9 Links Ensembl NCBI GeneCards UniProt Show fit	Ras association domain family member 9
chr5_-_122078249 Show fit	2.38	ENST00000231004.5	LOX Links Ensembl NCBI GeneCards UniProt Show fit	lysyl oxidase
chr8_+_109540602 Show fit	2.37	ENST00000530629.5 ENST00000620557.4	EBAG9 Links Ensembl NCBI GeneCards UniProt Show fit	estrogen receptor binding site associated antigen 9
chr2_-_98663464 Show fit	2.24	ENST00000414521.6	MGAT4A Links Ensembl NCBI GeneCards UniProt Show fit	alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
chr1_-_36464262 Show fit	2.23	ENST00000373116.6	MRPS15 Links Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein S15
chr3_+_130850585 Show fit	2.21	ENST00000505330.5 ENST00000504381.5 ENST00000507488.6	ATP2C1 Links Ensembl NCBI GeneCards UniProt Show fit	ATPase secretory pathway Ca2+ transporting 1
chr10_+_88990736 Show fit	2.17	ENST00000357339.6 ENST00000652046.1 ENST00000355279.2	FAS Links Ensembl NCBI GeneCards UniProt Show fit	Fas cell surface death receptor
chr8_+_109540075 Show fit	2.14	ENST00000614147.1 ENST00000337573.10	EBAG9 Links Ensembl NCBI GeneCards UniProt Show fit	estrogen receptor binding site associated antigen 9
chr3_-_120682215 Show fit	2.13	ENST00000283871.10	HGD Links Ensembl NCBI GeneCards UniProt Show fit	homogentisate 1,2-dioxygenase
chr12_+_66189208 Show fit	2.08	ENST00000261233.9	IRAK3 Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 receptor associated kinase 3
chr1_+_94418375 Show fit	2.06	ENST00000370214.9	ABCD3 Links Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily D member 3
chr1_+_94418435 Show fit	2.06	ENST00000647998.2	ABCD3 Links Ensembl NCBI GeneCards UniProt Show fit	ATP binding cassette subfamily D member 3
chr2_-_191014137 Show fit	2.05	ENST00000673777.1 ENST00000673942.1 ENST00000424722.6 ENST00000392322.7 ENST00000361099.8 ENST00000392323.6 ENST00000673816.1 ENST00000673847.1 ENST00000673952.1 ENST00000540176.6 ENST00000673841.1	STAT1 Links Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 1
chr4_+_77158252 Show fit	2.05	ENST00000395640.5	CCNG2 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin G2
chr21_-_26967057 Show fit	2.00	ENST00000284987.6	ADAMTS5 Links Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase with thrombospondin type 1 motif 5
chr6_+_30720335 Show fit	1.88	ENST00000327892.13	TUBB Links Ensembl NCBI GeneCards UniProt Show fit	tubulin beta class I
chr20_-_22585451 Show fit	1.84	ENST00000377115.4	FOXA2 Links Ensembl NCBI GeneCards UniProt Show fit	forkhead box A2
chr4_+_77158418 Show fit	1.83	ENST00000509972.1	CCNG2 Links Ensembl NCBI GeneCards UniProt Show fit	cyclin G2
chr17_-_79839387 Show fit	1.83	ENST00000448310.1 ENST00000269397.9	CBX4 Links Ensembl NCBI GeneCards UniProt Show fit	chromobox 4
chr22_+_17084920 Show fit	1.79	ENST00000612619.1 ENST00000319363.11	IL17RA Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 17 receptor A
chr3_+_12351493 Show fit	1.71	ENST00000683699.1	PPARG Links Ensembl NCBI GeneCards UniProt Show fit	peroxisome proliferator activated receptor gamma
chr17_-_49677976 Show fit	1.70	ENST00000665825.1 ENST00000508805.5 ENST00000515508.6 ENST00000451526.6 ENST00000507970.5	SPOP Links Ensembl NCBI GeneCards UniProt Show fit	speckle type BTB/POZ protein
chr1_+_162561504 Show fit	1.66	ENST00000271469.7 ENST00000367926.8	UAP1 Links Ensembl NCBI GeneCards UniProt Show fit	UDP-N-acetylglucosamine pyrophosphorylase 1
chr22_-_28712136 Show fit	1.59	ENST00000464581.6	CHEK2 Links Ensembl NCBI GeneCards UniProt Show fit	checkpoint kinase 2
chr19_-_1652576 Show fit	1.53	ENST00000453954.6 ENST00000395423.7 ENST00000262965.12 ENST00000588136.7	TCF3 Links Ensembl NCBI GeneCards UniProt Show fit	transcription factor 3
chr1_+_207088825 Show fit	1.44	ENST00000367078.8	C4BPB Links Ensembl NCBI GeneCards UniProt Show fit	complement component 4 binding protein beta
chr3_-_122514876 Show fit	1.42	ENST00000493510.1 ENST00000476916.5 ENST00000344337.11 ENST00000465882.5	KPNA1 Links Ensembl NCBI GeneCards UniProt Show fit	karyopherin subunit alpha 1
chr19_-_51645545 Show fit	1.42	ENST00000534261.3	SIGLEC5 Links Ensembl NCBI GeneCards UniProt Show fit	sialic acid binding Ig like lectin 5
chr1_-_67054100 Show fit	1.42	ENST00000235345.6	SLC35D1 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 35 member D1
chr11_-_64742937 Show fit	1.39	ENST00000394428.5 ENST00000394429.5	RASGRP2 Links Ensembl NCBI GeneCards UniProt Show fit	RAS guanyl releasing protein 2
chr2_+_113127588 Show fit	1.37	ENST00000409930.4	IL1RN Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 receptor antagonist
chr19_-_15331890 Show fit	1.29	ENST00000594841.5 ENST00000601941.1	BRD4 Links Ensembl NCBI GeneCards UniProt Show fit	bromodomain containing 4
chr11_-_4697831 Show fit	1.23	ENST00000641159.1 ENST00000396950.4 ENST00000532598.1	OR51C1P Links Ensembl NCBI GeneCards UniProt Show fit OR51E2 Links Ensembl NCBI GeneCards UniProt Show fit	olfactory receptor family 51 subfamily C member 1 pseudogene olfactory receptor family 51 subfamily E member 2
chr20_-_59007807 Show fit	1.22	ENST00000680386.1	CTSZ Links Ensembl NCBI GeneCards UniProt Show fit	cathepsin Z
chr17_-_43125300 Show fit	1.21	ENST00000497488.1 ENST00000354071.7 ENST00000489037.1 ENST00000470026.5 ENST00000644555.1 ENST00000586385.5 ENST00000591534.5 ENST00000591849.5	BRCA1 Links Ensembl NCBI GeneCards UniProt Show fit	BRCA1 DNA repair associated
chr20_-_1619996 Show fit	1.18	ENST00000381603.7 ENST00000381605.9 ENST00000279477.11 ENST00000568365.1 ENST00000564763.1	SIRPB1 Links Ensembl NCBI GeneCards UniProt Show fit ENSG00000260861.6 Links Ensembl NCBI GeneCards UniProt Show fit	signal regulatory protein beta 1 novel protein, SIRPB1-SIRPD readthrough
chr1_-_47231715 Show fit	1.16	ENST00000371884.6	TAL1 Links Ensembl NCBI GeneCards UniProt Show fit	TAL bHLH transcription factor 1, erythroid differentiation factor
chr4_-_39977836 Show fit	1.14	ENST00000303538.13 ENST00000503396.5	PDS5A Links Ensembl NCBI GeneCards UniProt Show fit	PDS5 cohesin associated factor A
chr3_+_42091316 Show fit	1.12	ENST00000327628.10	TRAK1 Links Ensembl NCBI GeneCards UniProt Show fit	trafficking kinesin protein 1
chr17_-_49678074 Show fit	1.12	ENST00000505581.5 ENST00000504102.6 ENST00000514121.6 ENST00000393328.6 ENST00000509079.6 ENST00000347630.6	SPOP Links Ensembl NCBI GeneCards UniProt Show fit	speckle type BTB/POZ protein
chr14_+_58298497 Show fit	1.08	ENST00000348476.7 ENST00000355431.8 ENST00000395168.7	ARID4A Links Ensembl NCBI GeneCards UniProt Show fit	AT-rich interaction domain 4A
chr12_+_66189254 Show fit	1.08	ENST00000457197.2	IRAK3 Links Ensembl NCBI GeneCards UniProt Show fit	interleukin 1 receptor associated kinase 3
chr8_-_25458389 Show fit	1.06	ENST00000221200.9	KCTD9 Links Ensembl NCBI GeneCards UniProt Show fit	potassium channel tetramerization domain containing 9
chr17_+_75093287 Show fit	1.04	ENST00000538213.6 ENST00000584118.1	SLC16A5 Links Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 16 member 5
chr1_-_168729187 Show fit	1.04	ENST00000367817.4	DPT Links Ensembl NCBI GeneCards UniProt Show fit	dermatopontin
chr2_-_191013955 Show fit	1.02	ENST00000409465.5	STAT1 Links Ensembl NCBI GeneCards UniProt Show fit	signal transducer and activator of transcription 1
chr4_-_76007501 Show fit	0.97	ENST00000264888.6	CXCL9 Links Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 9
chr7_+_23106267 Show fit	0.97	ENST00000409689.5 ENST00000410047.1	KLHL7 Links Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 7
chr9_-_85741874 Show fit	0.96	ENST00000357081.8 ENST00000337006.8 ENST00000628899.1	AGTPBP1 Links Ensembl NCBI GeneCards UniProt Show fit	ATP/GTP binding protein 1
chr19_+_40991274 Show fit	0.91	ENST00000324071.10	CYP2B6 Links Ensembl NCBI GeneCards UniProt Show fit	cytochrome P450 family 2 subfamily B member 6
chr19_-_54189550 Show fit	0.87	ENST00000338624.10 ENST00000245615.6	MBOAT7 Links Ensembl NCBI GeneCards UniProt Show fit	membrane bound O-acyltransferase domain containing 7
chr20_+_64084995 Show fit	0.87	ENST00000349451.3	OPRL1 Links Ensembl NCBI GeneCards UniProt Show fit	opioid related nociceptin receptor 1
chr3_-_158732442 Show fit	0.83	ENST00000479756.1 ENST00000237696.10	RARRES1 Links Ensembl NCBI GeneCards UniProt Show fit	retinoic acid receptor responder 1
chr11_+_15073562 Show fit	0.82	ENST00000533448.1 ENST00000324229.11	CALCB Links Ensembl NCBI GeneCards UniProt Show fit	calcitonin related polypeptide beta
chr2_-_77522347 Show fit	0.81	ENST00000409093.1 ENST00000409884.6 ENST00000409088.3	LRRTM4 Links Ensembl NCBI GeneCards UniProt Show fit	leucine rich repeat transmembrane neuronal 4
chr1_-_161118024 Show fit	0.79	ENST00000368010.4	PFDN2 Links Ensembl NCBI GeneCards UniProt Show fit	prefoldin subunit 2
chr6_+_167291309 Show fit	0.79	ENST00000230256.8	UNC93A Links Ensembl NCBI GeneCards UniProt Show fit	unc-93 homolog A
chr17_+_59209867 Show fit	0.77	ENST00000578922.1 ENST00000300917.10	SMG8 Links Ensembl NCBI GeneCards UniProt Show fit	SMG8 nonsense mediated mRNA decay factor
chr19_+_11239602 Show fit	0.69	ENST00000252453.12	ANGPTL8 Links Ensembl NCBI GeneCards UniProt Show fit	angiopoietin like 8
chr7_-_44848021 Show fit	0.69	ENST00000349299.7 ENST00000521529.5 ENST00000350771.7 ENST00000222690.10 ENST00000381124.9 ENST00000437072.5 ENST00000446531.1 ENST00000308153.9	H2AZ2 Links Ensembl NCBI GeneCards UniProt Show fit	H2A.Z variant histone 2
chr6_+_167291329 Show fit	0.65	ENST00000366829.2	UNC93A Links Ensembl NCBI GeneCards UniProt Show fit	unc-93 homolog A
chr19_-_6670151 Show fit	0.64	ENST00000675206.1	TNFSF14 Links Ensembl NCBI GeneCards UniProt Show fit	TNF superfamily member 14

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.9	26.8	GO:1903015	regulation of exo-alpha-sialidase activity(GO:1903015)
7.9	31.5	GO:0070221	sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
6.9	48.6	GO:1990822	regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
6.5	25.9	GO:1903786	mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
6.2	24.8	GO:0002384	hepatic immune response(GO:0002384)
6.1	18.3	GO:0060557	positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
5.6	129.0	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
5.6	22.3	GO:0072526	pyridine-containing compound catabolic process(GO:0072526)
4.9	34.1	GO:0034201	response to oleic acid(GO:0034201)
4.5	58.0	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
4.4	13.3	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
4.4	22.1	GO:0071727	toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
4.3	12.9	GO:2000296	negative regulation of hydrogen peroxide catabolic process(GO:2000296)
4.3	17.1	GO:0071918	pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
3.7	51.7	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
3.3	6.6	GO:0006097	glyoxylate cycle(GO:0006097)
3.3	6.6	GO:0002892	type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
3.2	9.7	GO:2001280	positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
3.2	15.8	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
3.1	9.2	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
2.9	8.6	GO:2000439	immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439)
2.8	13.9	GO:0006741	NADP biosynthetic process(GO:0006741)
2.6	15.7	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
2.2	8.9	GO:0043091	L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
2.1	6.4	GO:0052047	interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
2.1	6.3	GO:1903676	regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
2.1	6.2	GO:0043606	histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
2.0	6.1	GO:2000661	positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
1.9	15.6	GO:0001887	selenium compound metabolic process(GO:0001887)
1.9	5.7	GO:1901859	late nucleophagy(GO:0044805) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
1.9	18.7	GO:0051601	exocyst localization(GO:0051601)
1.8	75.1	GO:0050832	defense response to fungus(GO:0050832)
1.8	27.4	GO:0048298	positive regulation of isotype switching to IgA isotypes(GO:0048298)
1.8	5.3	GO:0060474	positive regulation of sperm motility involved in capacitation(GO:0060474)
1.7	10.0	GO:1900369	regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
1.7	5.0	GO:0001544	initiation of primordial ovarian follicle growth(GO:0001544)
1.6	4.8	GO:0072428	signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
1.6	9.3	GO:0048807	female genitalia morphogenesis(GO:0048807)
1.4	4.3	GO:0051365	cellular response to potassium ion starvation(GO:0051365)
1.4	4.1	GO:1902101	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
1.3	17.3	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
1.3	3.9	GO:0071373	cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373)
1.2	8.5	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
1.2	3.6	GO:1903526	negative regulation of membrane tubulation(GO:1903526)
1.2	10.6	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
1.1	11.5	GO:0043353	enucleate erythrocyte differentiation(GO:0043353) positive regulation of interferon-gamma biosynthetic process(GO:0045078)
1.1	8.0	GO:0097527	necroptotic signaling pathway(GO:0097527)
1.1	3.3	GO:0018160	peptidyl-pyrromethane cofactor linkage(GO:0018160)
1.0	3.1	GO:2000697	negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
1.0	7.2	GO:0061198	fungiform papilla formation(GO:0061198)
1.0	7.9	GO:0043152	induction of bacterial agglutination(GO:0043152)
1.0	42.0	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.9	11.9	GO:0036500	ATF6-mediated unfolded protein response(GO:0036500)
0.9	7.8	GO:0061052	negative regulation of cell proliferation involved in contact inhibition(GO:0060244) negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.8	1.5	GO:0002326	B cell lineage commitment(GO:0002326)
0.7	7.4	GO:0006983	ER overload response(GO:0006983)
0.7	13.4	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.7	3.9	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
0.6	16.7	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.6	1.8	GO:0045013	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.6	1.2	GO:0060374	mast cell differentiation(GO:0060374)
0.6	2.8	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.5	3.2	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.5	12.5	GO:0006907	pinocytosis(GO:0006907)
0.5	10.8	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.5	8.3	GO:0042761	fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.5	3.3	GO:0019240	citrulline biosynthetic process(GO:0019240)
0.5	1.4	GO:0070510	regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.4	4.0	GO:0015939	pantothenate metabolic process(GO:0015939)
0.4	2.2	GO:0032468	Golgi calcium ion homeostasis(GO:0032468)
0.4	17.7	GO:0048247	lymphocyte chemotaxis(GO:0048247)
0.4	6.1	GO:0010623	programmed cell death involved in cell development(GO:0010623)
0.3	36.0	GO:0036498	IRE1-mediated unfolded protein response(GO:0036498)
0.3	7.0	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.3	4.9	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.3	12.8	GO:0000717	nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.3	14.5	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
0.3	3.8	GO:0070327	thyroid hormone transport(GO:0070327)
0.3	1.4	GO:0045959	regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.3	2.0	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.3	1.1	GO:0098957	anterograde axonal transport of mitochondrion(GO:0098957)
0.3	1.1	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.3	1.9	GO:0060331	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.3	2.1	GO:0006572	tyrosine catabolic process(GO:0006572)
0.2	0.5	GO:0038091	VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.2	1.2	GO:1900133	regulation of renin secretion into blood stream(GO:1900133)
0.2	5.8	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2	2.6	GO:0021740	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2	2.8	GO:0048875	chemical homeostasis within a tissue(GO:0048875)
0.2	2.4	GO:0048251	elastic fiber assembly(GO:0048251)
0.2	3.6	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.2	0.6	GO:0060003	copper ion export(GO:0060003)
0.2	1.4	GO:2000660	negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2	0.9	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.2	10.2	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.2	6.0	GO:0034198	cellular response to amino acid starvation(GO:0034198)
0.1	0.6	GO:0015910	peroxisomal long-chain fatty acid import(GO:0015910)
0.1	4.3	GO:0042772	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.1	2.8	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1	8.5	GO:0050819	negative regulation of coagulation(GO:0050819)
0.1	0.6	GO:0015677	copper ion import(GO:0015677) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1	1.7	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1	6.0	GO:0006458	'de novo' protein folding(GO:0006458)
0.1	2.2	GO:0006491	N-glycan processing(GO:0006491)
0.1	1.5	GO:0021694	cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1	5.3	GO:0005978	glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1	0.5	GO:0032916	negative regulation of cardiac muscle adaptation(GO:0010616) evasion or tolerance of host defenses by virus(GO:0019049) positive regulation of transforming growth factor beta3 production(GO:0032916) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) negative regulation of lung blood pressure(GO:0061767) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.1	5.0	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.1	1.4	GO:0019054	modulation by virus of host process(GO:0019054)
0.1	1.1	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.1	0.2	GO:0060585	positive regulation of the force of heart contraction by chemical signal(GO:0003099) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0	1.7	GO:1903861	positive regulation of dendrite extension(GO:1903861)
0.0	5.5	GO:0008543	fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0	0.7	GO:0044342	type B pancreatic cell proliferation(GO:0044342)
0.0	1.0	GO:0030199	collagen fibril organization(GO:0030199)
0.0	0.2	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0	0.3	GO:0042738	exogenous drug catabolic process(GO:0042738)
0.0	0.3	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0	0.6	GO:0006337	nucleosome disassembly(GO:0006337)
0.0	0.4	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.2	GO:0097264	self proteolysis(GO:0097264)
0.0	1.8	GO:0016925	protein sumoylation(GO:0016925)
0.0	1.9	GO:0051225	spindle assembly(GO:0051225)
0.0	0.2	GO:0042249	establishment of planar polarity of embryonic epithelium(GO:0042249)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.7	51.7	GO:0097452	GAIT complex(GO:0097452)
5.0	24.8	GO:0005896	interleukin-6 receptor complex(GO:0005896)
4.4	13.3	GO:0072557	IPAF inflammasome complex(GO:0072557)
3.2	12.9	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
3.2	12.8	GO:0071942	XPC complex(GO:0071942)
2.5	22.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
2.3	15.8	GO:0044530	supraspliceosomal complex(GO:0044530)
1.2	14.4	GO:0005577	fibrinogen complex(GO:0005577)
1.2	9.2	GO:0005827	polar microtubule(GO:0005827)
1.1	18.7	GO:0000145	exocyst(GO:0000145)
0.9	2.8	GO:0032426	stereocilium tip(GO:0032426)
0.9	19.9	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.7	7.0	GO:0031595	nuclear proteasome complex(GO:0031595)
0.7	3.9	GO:0001940	male pronucleus(GO:0001940)
0.6	23.4	GO:1904724	tertiary granule lumen(GO:1904724)
0.5	112.7	GO:0101002	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.4	45.0	GO:0043195	terminal bouton(GO:0043195)
0.4	4.2	GO:0005664	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.4	6.3	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.4	8.0	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.4	7.2	GO:0016580	Sin3 complex(GO:0016580)
0.3	37.4	GO:0017053	transcriptional repressor complex(GO:0017053)
0.3	5.3	GO:0097225	sperm midpiece(GO:0097225)
0.3	26.3	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.3	1.4	GO:0031436	BRCA1-BARD1 complex(GO:0031436)
0.2	7.8	GO:0071437	invadopodium(GO:0071437)
0.2	4.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.2	7.9	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.2	3.6	GO:0001891	phagocytic cup(GO:0001891)
0.2	1.9	GO:0005641	nuclear envelope lumen(GO:0005641)
0.2	2.4	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.1	3.3	GO:0036019	endolysosome(GO:0036019)
0.1	20.1	GO:0016605	PML body(GO:0016605)
0.1	22.5	GO:0032993	protein-DNA complex(GO:0032993)
0.1	11.3	GO:0042579	peroxisome(GO:0005777) microbody(GO:0042579)
0.1	2.6	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.1	12.4	GO:0035578	azurophil granule lumen(GO:0035578)
0.1	45.1	GO:0016323	basolateral plasma membrane(GO:0016323)
0.1	1.8	GO:0035102	PRC1 complex(GO:0035102)
0.1	0.8	GO:0016272	prefoldin complex(GO:0016272)
0.1	5.3	GO:0016234	inclusion body(GO:0016234)
0.1	9.7	GO:0005901	caveola(GO:0005901)
0.1	7.4	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.1	2.2	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1	2.8	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.1	6.6	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.1	3.8	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1	4.3	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.1	8.6	GO:0043204	perikaryon(GO:0043204)
0.1	19.2	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.1	4.9	GO:0031225	anchored component of membrane(GO:0031225)
0.1	26.3	GO:0005743	mitochondrial inner membrane(GO:0005743)
0.1	3.8	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	0.5	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.1	8.1	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	10.4	GO:0010008	endosome membrane(GO:0010008)
0.0	5.5	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.0	2.0	GO:0005581	collagen trimer(GO:0005581)
0.0	49.8	GO:0005615	extracellular space(GO:0005615)
0.0	6.0	GO:0005840	ribosome(GO:0005840)
0.0	6.5	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	1.2	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	16.5	GO:0005764	lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0	2.7	GO:0044217	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	1.1	GO:1904115	axon cytoplasm(GO:1904115)
0.0	32.7	GO:0005783	endoplasmic reticulum(GO:0005783)
0.0	3.4	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.0	2.2	GO:0005802	trans-Golgi network(GO:0005802)
0.0	10.2	GO:0005815	microtubule organizing center(GO:0005815)
0.0	1.4	GO:0032587	ruffle membrane(GO:0032587)
0.0	1.1	GO:0000775	chromosome, centromeric region(GO:0000775)
0.0	1.2	GO:0030667	secretory granule membrane(GO:0030667)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
14.5	58.0	GO:0004074	biliverdin reductase activity(GO:0004074)
12.9	129.0	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
6.4	19.1	GO:0070119	ciliary neurotrophic factor binding(GO:0070119)
5.7	17.1	GO:0015265	urea channel activity(GO:0015265)
5.6	22.3	GO:0002060	purine nucleobase binding(GO:0002060)
5.5	22.1	GO:0016019	peptidoglycan receptor activity(GO:0016019)
5.2	31.5	GO:0016672	oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672)
4.0	48.6	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
3.9	27.5	GO:0001849	complement component C1q binding(GO:0001849)
3.9	15.7	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
3.5	17.3	GO:1990254	keratin filament binding(GO:1990254)
3.1	9.2	GO:0031208	POZ domain binding(GO:0031208)
2.9	8.6	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
2.8	8.3	GO:0080023	3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
2.4	9.7	GO:0050473	arachidonate 15-lipoxygenase activity(GO:0050473)
2.2	37.6	GO:0001222	transcription corepressor binding(GO:0001222)
2.2	6.6	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450)
1.8	12.5	GO:0030492	hemoglobin binding(GO:0030492)
1.8	5.3	GO:0031731	CCR6 chemokine receptor binding(GO:0031731)
1.5	6.1	GO:0004909	interleukin-1, Type I, activating receptor activity(GO:0004909)
1.5	4.5	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
1.5	10.2	GO:0004873	asialoglycoprotein receptor activity(GO:0004873)
1.4	4.3	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
1.4	34.1	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
1.3	8.0	GO:0043120	tumor necrosis factor binding(GO:0043120)
1.3	51.7	GO:0008143	poly(A) binding(GO:0008143)
1.3	10.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
1.2	6.2	GO:0016841	ammonia-lyase activity(GO:0016841)
1.2	19.6	GO:0005149	interleukin-1 receptor binding(GO:0005149)
1.2	4.9	GO:0017159	pantetheine hydrolase activity(GO:0017159)
1.2	16.7	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.2	5.8	GO:0005138	interleukin-6 receptor binding(GO:0005138)
1.1	3.4	GO:0070052	collagen V binding(GO:0070052)
1.1	3.3	GO:0004418	hydroxymethylbilane synthase activity(GO:0004418)
1.1	13.3	GO:0050700	CARD domain binding(GO:0050700)
1.1	11.9	GO:0046790	virion binding(GO:0046790)
1.1	6.3	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.9	5.7	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.9	2.8	GO:0032427	GBD domain binding(GO:0032427)
0.9	3.7	GO:0016524	latrotoxin receptor activity(GO:0016524)
0.8	3.3	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.8	2.4	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.8	7.0	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.7	26.1	GO:0001221	transcription cofactor binding(GO:0001221)
0.7	3.3	GO:0004522	ribonuclease A activity(GO:0004522)
0.6	31.7	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.6	6.4	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.6	2.5	GO:0051748	UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.6	23.1	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.6	9.3	GO:0019841	retinal binding(GO:0016918) retinol binding(GO:0019841)
0.5	5.3	GO:0035251	UDP-glucosyltransferase activity(GO:0035251)
0.5	14.3	GO:0003951	NAD+ kinase activity(GO:0003951)
0.5	8.1	GO:0070513	death domain binding(GO:0070513)
0.4	7.2	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.4	2.8	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.4	3.6	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.4	1.5	GO:0070644	vitamin D response element binding(GO:0070644)
0.4	11.5	GO:0008301	DNA binding, bending(GO:0008301)
0.4	43.2	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.3	12.6	GO:0048020	CCR chemokine receptor binding(GO:0048020)
0.3	8.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.3	4.3	GO:0008494	translation activator activity(GO:0008494)
0.3	22.6	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.3	14.5	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.3	2.2	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3	0.6	GO:0004008	copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.3	5.5	GO:0008266	poly(U) RNA binding(GO:0008266)
0.3	9.2	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.3	1.8	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.3	1.7	GO:0070569	uridylyltransferase activity(GO:0070569)
0.2	1.0	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.2	12.8	GO:0031593	polyubiquitin binding(GO:0031593)
0.2	0.9	GO:0001626	nociceptin receptor activity(GO:0001626)
0.2	1.9	GO:0050692	DBD domain binding(GO:0050692)
0.2	10.9	GO:0016504	peptidase activator activity(GO:0016504)
0.2	1.4	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.2	2.5	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2	0.5	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2	0.6	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1	38.3	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	7.8	GO:0048365	Rac GTPase binding(GO:0048365)
0.1	0.3	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1	13.1	GO:0000149	SNARE binding(GO:0000149)
0.1	1.8	GO:0032183	SUMO transferase activity(GO:0019789) SUMO binding(GO:0032183)
0.1	6.1	GO:0004520	endodeoxyribonuclease activity(GO:0004520)
0.1	0.6	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.1	0.5	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.1	2.1	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1	1.9	GO:0032794	GTPase activating protein binding(GO:0032794)
0.1	1.4	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	5.8	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1	7.9	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.1	41.8	GO:0003779	actin binding(GO:0003779)
0.1	3.9	GO:0097472	cyclin-dependent protein kinase activity(GO:0097472)
0.1	1.1	GO:0097602	cullin family protein binding(GO:0097602)
0.1	1.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	2.5	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	24.1	GO:0004930	G-protein coupled receptor activity(GO:0004930)
0.0	5.9	GO:0001047	core promoter binding(GO:0001047)
0.0	1.1	GO:0042056	chemoattractant activity(GO:0042056)
0.0	3.6	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	4.1	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	1.4	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	1.4	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.6	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	1.1	GO:0004407	histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0	0.2	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	2.8	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.0	1.6	GO:0050840	extracellular matrix binding(GO:0050840)
0.0	0.8	GO:0044183	protein binding involved in protein folding(GO:0044183)
0.0	0.8	GO:0005184	neuropeptide hormone activity(GO:0005184)
0.0	4.1	GO:0004721	phosphoprotein phosphatase activity(GO:0004721)
0.0	1.2	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	2.2	GO:0003735	structural constituent of ribosome(GO:0003735)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	24.8	ST STAT3 PATHWAY	STAT3 Pathway
1.1	31.6	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.7	25.1	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.5	27.5	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.4	26.5	PID AURORA B PATHWAY	Aurora B signaling
0.4	7.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.4	22.8	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.4	3.1	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.4	13.3	PID AURORA A PATHWAY	Aurora A signaling
0.3	14.5	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.3	9.7	PID S1P S1P1 PATHWAY	S1P1 pathway
0.3	14.2	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.3	6.4	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3	5.0	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.3	8.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2	6.3	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.2	8.1	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.2	4.5	PID IL1 PATHWAY	IL1-mediated signaling events
0.2	10.8	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.2	12.0	PID BMP PATHWAY	BMP receptor signaling
0.2	15.7	PID IL12 2PATHWAY	IL12-mediated signaling events
0.2	3.9	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2	11.9	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.1	7.0	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	1.5	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.1	3.9	PID ATM PATHWAY	ATM pathway
0.1	1.4	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.1	6.1	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	3.0	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.1	1.0	PID IL23 PATHWAY	IL23-mediated signaling events
0.1	4.1	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	4.1	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	4.5	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.1	22.7	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	2.8	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	3.8	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.0	1.4	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.5	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.0	61.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
2.0	37.4	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
1.9	34.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
1.7	22.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
1.6	27.9	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
1.4	13.9	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
1.3	17.1	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
1.1	17.0	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.9	11.9	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.9	44.9	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.7	13.3	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.6	14.1	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.5	28.7	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.5	17.3	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.5	37.6	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.5	29.3	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.5	11.0	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.4	22.1	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.4	12.8	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.4	4.3	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.3	3.9	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3	8.0	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.3	4.8	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.3	7.9	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.2	34.4	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.2	5.9	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.2	5.0	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.2	5.8	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.2	6.5	REACTOME AMYLOIDS	Genes involved in Amyloids
0.2	3.6	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.2	3.9	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.1	3.0	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.1	3.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	6.6	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.1	10.0	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.1	1.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	19.8	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.1	8.2	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.1	2.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	1.4	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.1	2.6	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	1.2	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	1.4	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.1	12.5	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1	5.3	REACTOME GLUCOSE METABOLISM	Genes involved in Glucose metabolism
0.0	1.8	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	5.8	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	1.2	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	3.9	REACTOME SIGNALING BY PDGF	Genes involved in Signaling by PDGF
0.0	1.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	1.9	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.8	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	1.9	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	2.8	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.0	0.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	1.6	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events