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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for CEBPE_CEBPD

Z-value: 0.89

Motif logo

Transcription factors associated with CEBPE_CEBPD

Gene Symbol Gene ID Gene Info
ENSG00000092067.6 CEBPE
ENSG00000221869.5 CEBPD

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPDhg38_v1_chr8_-_47738153_477381730.414.8e-10Click!
CEBPEhg38_v1_chr14_-_23119248_23119265-0.128.4e-02Click!

Activity profile of CEBPE_CEBPD motif

Sorted Z-values of CEBPE_CEBPD motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPE_CEBPD

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr9_-_91423819 42.01 ENST00000297689.4
nuclear factor, interleukin 3 regulated
chr5_+_96662214 34.61 ENST00000395812.6
calpastatin
chr5_+_96662366 33.15 ENST00000675179.1
ENST00000421689.6
ENST00000674984.1
ENST00000512620.5
calpastatin
chr16_-_84618041 32.75 ENST00000564057.1
coactosin like F-actin binding protein 1
chr5_+_96662314 32.63 ENST00000674702.1
calpastatin
chr16_-_84618067 32.30 ENST00000262428.5
coactosin like F-actin binding protein 1
chr15_+_45635017 31.49 ENST00000260324.12
sulfide quinone oxidoreductase
chr5_+_96662046 28.59 ENST00000338252.7
ENST00000508830.5
calpastatin
chr3_+_157436842 27.54 ENST00000295927.4
pentraxin 3
chr19_-_40465760 27.33 ENST00000643519.1
biliverdin reductase B
chr19_-_40465736 26.11 ENST00000263368.9
ENST00000595483.5
biliverdin reductase B
chr14_+_20469399 22.32 ENST00000361505.10
ENST00000553591.1
purine nucleoside phosphorylase
chr6_-_85644043 21.35 ENST00000678930.1
ENST00000678355.1
synaptotagmin binding cytoplasmic RNA interacting protein
chr14_-_22815421 19.76 ENST00000674313.1
ENST00000555959.1
solute carrier family 7 member 7
chr1_-_156751654 19.04 ENST00000357325.10
heparin binding growth factor
chr14_+_103121457 18.74 ENST00000333007.8
TNF alpha induced protein 2
chr1_-_156751597 18.60 ENST00000537739.5
heparin binding growth factor
chr2_-_112836702 18.27 ENST00000416750.1
ENST00000263341.7
ENST00000418817.5
interleukin 1 beta
chr10_+_17228215 17.29 ENST00000544301.7
vimentin
chr4_-_184826030 17.12 ENST00000507295.5
ENST00000504900.5
ENST00000454703.6
acyl-CoA synthetase long chain family member 1
chr15_+_58138368 17.10 ENST00000219919.9
ENST00000536493.1
aquaporin 9
chr4_-_184825960 17.01 ENST00000281455.7
acyl-CoA synthetase long chain family member 1
chr19_-_2042066 16.69 ENST00000591588.1
ENST00000591142.5
MAPK interacting serine/threonine kinase 2
chr12_-_122716790 16.10 ENST00000528880.3
hydroxycarboxylic acid receptor 3
chr6_-_85643832 16.03 ENST00000677771.1
ENST00000676688.1
synaptotagmin binding cytoplasmic RNA interacting protein
chr12_-_122703346 15.79 ENST00000328880.6
hydroxycarboxylic acid receptor 2
chr17_-_36090133 15.73 ENST00000613922.2
C-C motif chemokine ligand 3
chr14_-_22815801 14.94 ENST00000397532.9
solute carrier family 7 member 7
chr2_-_177263522 14.79 ENST00000448782.5
ENST00000446151.6
nuclear factor, erythroid 2 like 2
chr6_-_85643778 14.37 ENST00000676637.1
ENST00000678528.1
synaptotagmin binding cytoplasmic RNA interacting protein
chr1_-_1779976 13.94 ENST00000378625.5
NAD kinase
chr14_-_22815856 13.90 ENST00000554758.1
ENST00000397528.8
solute carrier family 7 member 7
chr5_-_140633167 13.68 ENST00000302014.11
CD14 molecule
chr19_+_859654 13.56 ENST00000592860.2
ENST00000327726.11
complement factor D
chr11_-_105035113 13.28 ENST00000526568.5
ENST00000531166.5
ENST00000534497.5
ENST00000527979.5
ENST00000533400.6
ENST00000528974.1
ENST00000525825.5
ENST00000353247.9
ENST00000446369.5
ENST00000436863.7
caspase 1
chr16_+_72054477 12.95 ENST00000355906.10
ENST00000570083.5
ENST00000228226.12
ENST00000398131.6
ENST00000569639.5
ENST00000564499.5
ENST00000357763.8
ENST00000613898.1
ENST00000562526.5
ENST00000565574.5
ENST00000568417.6
haptoglobin
chr9_+_107283256 12.82 ENST00000358015.8
RAD23 homolog B, nucleotide excision repair protein
chr17_-_36196748 12.58 ENST00000619989.1
C-C motif chemokine ligand 3 like 1
chr3_+_186613052 12.46 ENST00000411641.7
ENST00000273784.5
alpha 2-HS glycoprotein
chr20_-_35742207 12.07 ENST00000397370.3
ENST00000528062.7
ENST00000374038.7
ENST00000253363.11
ENST00000361162.10
RNA binding motif protein 39
chr12_+_103930600 11.91 ENST00000680316.1
ENST00000679861.1
heat shock protein 90 beta family member 1
chr12_+_101877571 11.74 ENST00000258534.13
DNA damage regulated autophagy modulator 1
chr19_+_33373694 11.48 ENST00000284000.9
CCAAT enhancer binding protein gamma
chr17_+_7558774 11.33 ENST00000396545.4
TNF superfamily member 13
chr2_-_177263800 11.12 ENST00000397063.8
ENST00000421929.5
nuclear factor, erythroid 2 like 2
chr1_+_154405326 10.66 ENST00000368485.8
interleukin 6 receptor
chr5_+_50667405 9.93 ENST00000505554.5
poly(ADP-ribose) polymerase family member 8
chr16_-_30445865 9.74 ENST00000478753.5
selenophosphate synthetase 2
chr1_-_186680411 9.69 ENST00000367468.10
prostaglandin-endoperoxide synthase 2
chr6_+_31927683 9.52 ENST00000456570.5
novel complement component 2 (C2) and complement factor B (CFB) protein
chr19_-_15332507 9.47 ENST00000679869.1
ENST00000360016.9
bromodomain containing 4
chr10_-_93601228 9.30 ENST00000371464.8
retinol binding protein 4
chr2_-_224497816 9.25 ENST00000451538.1
cullin 3
chr17_+_7558712 8.64 ENST00000338784.9
ENST00000625791.2
TNF superfamily member 13
chr3_+_46354072 8.56 ENST00000445132.3
ENST00000421659.1
C-C motif chemokine receptor 2
chr5_-_140633690 8.41 ENST00000512545.1
ENST00000401743.6
CD14 molecule
chr1_+_154405193 8.40 ENST00000622330.4
ENST00000344086.8
interleukin 6 receptor
chr1_-_151059561 8.24 ENST00000357235.6
ENST00000540998.5
CDC42 small effector 1
chr5_-_10761156 8.07 ENST00000432074.2
ENST00000230895.11
death associated protein
chr5_+_50666917 7.61 ENST00000514342.6
poly(ADP-ribose) polymerase family member 8
chr19_+_6887560 7.60 ENST00000250572.12
ENST00000381407.9
ENST00000450315.7
ENST00000312053.9
ENST00000381404.8
adhesion G protein-coupled receptor E1
chr4_-_102825526 7.59 ENST00000504211.5
ENST00000508476.5
ubiquitin conjugating enzyme E2 D3
chr17_+_7558465 7.47 ENST00000349228.8
TNF superfamily member 13
chr17_-_63773534 7.43 ENST00000403162.7
ENST00000582252.1
ENST00000225726.10
coiled-coil domain containing 47
chr1_+_32292067 7.16 ENST00000373548.8
ENST00000428704.1
histone deacetylase 1
chr4_-_102825767 6.87 ENST00000505207.5
ENST00000502404.5
ENST00000507845.5
ubiquitin conjugating enzyme E2 D3
chr2_-_208254232 6.64 ENST00000415913.5
ENST00000415282.5
ENST00000446179.5
isocitrate dehydrogenase (NADP(+)) 1
chr12_+_7060676 6.61 ENST00000617865.4
ENST00000402681.7
ENST00000360817.10
complement C1s
chr19_-_6720641 6.58 ENST00000245907.11
complement C3
chr2_-_215436061 6.42 ENST00000421182.5
ENST00000432072.6
ENST00000323926.10
ENST00000336916.8
ENST00000357867.8
ENST00000359671.5
ENST00000446046.5
ENST00000354785.11
ENST00000356005.8
ENST00000443816.5
ENST00000426059.1
fibronectin 1
chr2_+_218382265 6.40 ENST00000233202.11
solute carrier family 11 member 1
chr3_+_136930469 6.31 ENST00000469404.1
ENST00000467911.1
NCK adaptor protein 1
chr12_-_95996302 6.23 ENST00000261208.8
ENST00000538703.5
ENST00000541929.5
histidine ammonia-lyase
chr3_-_58214671 6.13 ENST00000460422.1
ENST00000483681.5
deoxyribonuclease 1 like 3
chr2_+_102104563 6.13 ENST00000409589.5
ENST00000409329.5
interleukin 1 receptor type 1
chr10_+_14838288 5.96 ENST00000640019.3
ENST00000493178.1
ENST00000378372.8
novel protein
heat shock protein family A (Hsp70) member 14
chr10_-_80289647 5.84 ENST00000372213.8
methionine adenosyltransferase 1A
chr1_-_154627576 5.84 ENST00000648311.1
adenosine deaminase RNA specific
chrX_-_136880715 5.82 ENST00000431446.7
ENST00000320676.11
ENST00000562646.5
RNA binding motif protein X-linked
chr7_+_22727147 5.76 ENST00000426291.5
ENST00000401651.5
ENST00000258743.10
ENST00000407492.5
ENST00000401630.7
ENST00000406575.1
interleukin 6
chr1_+_209768597 5.72 ENST00000487271.5
ENST00000477431.1
TRAF3 interacting protein 3
chr3_+_11272413 5.67 ENST00000446450.6
ENST00000354956.9
ENST00000354449.7
ENST00000419112.5
autophagy related 7
chr6_+_31927703 5.65 ENST00000418949.6
ENST00000299367.10
ENST00000383177.7
ENST00000477310.1
complement C2
novel complement component 2 (C2) and complement factor B (CFB) protein
chr5_+_50666950 5.60 ENST00000513738.5
ENST00000503665.5
ENST00000514067.6
ENST00000503046.5
poly(ADP-ribose) polymerase family member 8
chr5_-_179623098 5.53 ENST00000630639.1
ENST00000329433.10
ENST00000510411.5
heterogeneous nuclear ribonucleoprotein H1
chr10_-_17617235 5.48 ENST00000466335.1
3-hydroxyacyl-CoA dehydratase 1
chr20_+_35172046 5.41 ENST00000216968.5
protein C receptor
chr17_-_7114648 5.33 ENST00000355035.9
asialoglycoprotein receptor 2
chr8_-_6877928 5.31 ENST00000297439.4
defensin beta 1
chr19_-_48993300 5.31 ENST00000323798.8
ENST00000263276.6
glycogen synthase 1
chr12_-_7109176 5.18 ENST00000545280.5
ENST00000543933.5
ENST00000545337.1
ENST00000266542.9
ENST00000544702.5
complement C1r subcomponent like
chr16_-_21652598 5.13 ENST00000569602.1
ENST00000268389.6
immunoglobulin superfamily member 6
chr14_+_101809855 5.08 ENST00000557714.1
ENST00000445439.7
ENST00000334743.9
ENST00000557095.5
protein phosphatase 2 regulatory subunit B'gamma
chr6_+_108656346 4.96 ENST00000540898.1
forkhead box O3
chr6_+_31927486 4.96 ENST00000442278.6
complement C2
chr3_-_46464868 4.93 ENST00000417439.5
ENST00000231751.9
ENST00000431944.1
lactotransferrin
chr17_-_7114813 4.86 ENST00000254850.11
asialoglycoprotein receptor 2
chr6_-_132734692 4.86 ENST00000509351.5
ENST00000417437.6
ENST00000423615.6
ENST00000427187.6
ENST00000414302.7
ENST00000367927.9
ENST00000450865.2
vanin 3
chr1_+_209768482 4.69 ENST00000367023.5
TRAF3 interacting protein 3
chr4_-_154590735 4.59 ENST00000403106.8
ENST00000622532.1
ENST00000651975.1
fibrinogen alpha chain
chr7_+_43764191 4.53 ENST00000424330.1
biliverdin reductase A
chr7_-_36724380 4.52 ENST00000617267.4
acyloxyacyl hydrolase
chr15_-_63157464 4.32 ENST00000330964.10
ENST00000635699.1
ENST00000439025.1
ribosomal protein S27 like
chr20_+_57561103 4.31 ENST00000319441.6
phosphoenolpyruvate carboxykinase 1
chr7_+_150368189 4.24 ENST00000519397.1
ENST00000479668.5
replication initiator 1
chr1_-_154608705 4.18 ENST00000649749.1
ENST00000648871.1
adenosine deaminase RNA specific
chr11_-_77474041 4.14 ENST00000278568.8
p21 (RAC1) activated kinase 1
chr14_-_55191534 4.08 ENST00000395425.6
ENST00000247191.7
DLG associated protein 5
chr2_-_24328113 4.08 ENST00000622089.4
intersectin 2
chr4_-_121823843 3.94 ENST00000274026.10
cyclin A2
chr19_+_10718047 3.86 ENST00000585892.5
ENST00000355667.11
ENST00000389253.9
ENST00000359692.10
dynamin 2
chr13_-_46105009 3.84 ENST00000439329.5
ENST00000674625.1
ENST00000181383.10
carboxypeptidase B2
chrX_-_106038721 3.77 ENST00000372563.2
serpin family A member 7
chr1_+_81800368 3.69 ENST00000674489.1
ENST00000674442.1
ENST00000674419.1
ENST00000674407.1
ENST00000674168.1
ENST00000674307.1
ENST00000674209.1
ENST00000370715.5
ENST00000370713.5
ENST00000319517.10
ENST00000627151.2
ENST00000370717.6
adhesion G protein-coupled receptor L2
chr11_-_77474087 3.68 ENST00000356341.8
p21 (RAC1) activated kinase 1
chr11_-_47426216 3.62 ENST00000530651.5
ENST00000524447.6
ENST00000531051.6
ENST00000526993.1
ENST00000602866.5
proteasome 26S subunit, ATPase 3
chr8_-_101204697 3.58 ENST00000517844.5
zinc finger protein 706
chr15_+_39581068 3.42 ENST00000397591.2
ENST00000260356.6
thrombospondin 1
chr11_+_119085200 3.34 ENST00000650101.1
hydroxymethylbilane synthase
chr11_-_47426419 3.33 ENST00000298852.8
ENST00000530912.5
ENST00000619920.4
proteasome 26S subunit, ATPase 3
chr14_+_20955484 3.31 ENST00000304625.3
ribonuclease A family member 2
chr10_-_95656643 3.29 ENST00000371221.3
ENST00000371224.7
aldehyde dehydrogenase 18 family member A1
chr3_+_186666003 3.28 ENST00000232003.5
histidine rich glycoprotein
chr22_-_28711931 3.16 ENST00000434810.5
ENST00000456369.5
checkpoint kinase 2
chr10_+_88990531 3.12 ENST00000355740.7
Fas cell surface death receptor
chr3_+_186717348 3.06 ENST00000447445.1
ENST00000287611.8
ENST00000644859.2
kininogen 1
chr11_+_18266254 3.03 ENST00000532858.5
ENST00000649195.1
ENST00000356524.9
ENST00000405158.2
serum amyloid A1
chr10_-_17617326 2.86 ENST00000326961.6
ENST00000361271.8
3-hydroxyacyl-CoA dehydratase 1
chr15_-_82952683 2.85 ENST00000450735.7
ENST00000304231.12
homer scaffold protein 2
chr2_+_46542474 2.78 ENST00000238738.9
ras homolog family member Q
chr14_+_101809795 2.77 ENST00000350249.7
ENST00000557621.5
ENST00000556946.1
protein phosphatase 2 regulatory subunit B'gamma
chr10_+_88990621 2.72 ENST00000352159.8
Fas cell surface death receptor
chr14_-_45253161 2.71 ENST00000451174.1
ENST00000310806.9
MIS18 binding protein 1
chr9_-_14314132 2.62 ENST00000380953.6
nuclear factor I B
chr1_-_111200633 2.53 ENST00000357640.9
DENN domain containing 2D
chr6_+_131573219 2.51 ENST00000356962.2
ENST00000368087.8
ENST00000673427.1
ENST00000640973.1
arginase 1
chr2_+_63842325 2.51 ENST00000445915.6
ENST00000475462.5
UDP-glucose pyrophosphorylase 2
chr19_-_41439899 2.50 ENST00000597457.5
ENST00000589970.5
ENST00000595425.5
ENST00000438807.7
ENST00000589102.1
ENST00000221943.14
ENST00000592922.6
distal membrane arm assembly complex 2
chr12_-_85836372 2.41 ENST00000361228.5
Ras association domain family member 9
chr5_-_122078249 2.38 ENST00000231004.5
lysyl oxidase
chr8_+_109540602 2.37 ENST00000530629.5
ENST00000620557.4
estrogen receptor binding site associated antigen 9
chr2_-_98663464 2.24 ENST00000414521.6
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A
chr1_-_36464262 2.23 ENST00000373116.6
mitochondrial ribosomal protein S15
chr3_+_130850585 2.21 ENST00000505330.5
ENST00000504381.5
ENST00000507488.6
ATPase secretory pathway Ca2+ transporting 1
chr10_+_88990736 2.17 ENST00000357339.6
ENST00000652046.1
ENST00000355279.2
Fas cell surface death receptor
chr8_+_109540075 2.14 ENST00000614147.1
ENST00000337573.10
estrogen receptor binding site associated antigen 9
chr3_-_120682215 2.13 ENST00000283871.10
homogentisate 1,2-dioxygenase
chr12_+_66189208 2.08 ENST00000261233.9
interleukin 1 receptor associated kinase 3
chr1_+_94418375 2.06 ENST00000370214.9
ATP binding cassette subfamily D member 3
chr1_+_94418435 2.06 ENST00000647998.2
ATP binding cassette subfamily D member 3
chr2_-_191014137 2.05 ENST00000673777.1
ENST00000673942.1
ENST00000424722.6
ENST00000392322.7
ENST00000361099.8
ENST00000392323.6
ENST00000673816.1
ENST00000673847.1
ENST00000673952.1
ENST00000540176.6
ENST00000673841.1
signal transducer and activator of transcription 1
chr4_+_77158252 2.05 ENST00000395640.5
cyclin G2
chr21_-_26967057 2.00 ENST00000284987.6
ADAM metallopeptidase with thrombospondin type 1 motif 5
chr6_+_30720335 1.88 ENST00000327892.13
tubulin beta class I
chr20_-_22585451 1.84 ENST00000377115.4
forkhead box A2
chr4_+_77158418 1.83 ENST00000509972.1
cyclin G2
chr17_-_79839387 1.83 ENST00000448310.1
ENST00000269397.9
chromobox 4
chr22_+_17084920 1.79 ENST00000612619.1
ENST00000319363.11
interleukin 17 receptor A
chr3_+_12351493 1.71 ENST00000683699.1
peroxisome proliferator activated receptor gamma
chr17_-_49677976 1.70 ENST00000665825.1
ENST00000508805.5
ENST00000515508.6
ENST00000451526.6
ENST00000507970.5
speckle type BTB/POZ protein
chr1_+_162561504 1.66 ENST00000271469.7
ENST00000367926.8
UDP-N-acetylglucosamine pyrophosphorylase 1
chr22_-_28712136 1.59 ENST00000464581.6
checkpoint kinase 2
chr19_-_1652576 1.53 ENST00000453954.6
ENST00000395423.7
ENST00000262965.12
ENST00000588136.7
transcription factor 3
chr1_+_207088825 1.44 ENST00000367078.8
complement component 4 binding protein beta
chr3_-_122514876 1.42 ENST00000493510.1
ENST00000476916.5
ENST00000344337.11
ENST00000465882.5
karyopherin subunit alpha 1
chr19_-_51645545 1.42 ENST00000534261.3
sialic acid binding Ig like lectin 5
chr1_-_67054100 1.42 ENST00000235345.6
solute carrier family 35 member D1
chr11_-_64742937 1.39 ENST00000394428.5
ENST00000394429.5
RAS guanyl releasing protein 2
chr2_+_113127588 1.37 ENST00000409930.4
interleukin 1 receptor antagonist
chr19_-_15331890 1.29 ENST00000594841.5
ENST00000601941.1
bromodomain containing 4
chr11_-_4697831 1.23 ENST00000641159.1
ENST00000396950.4
ENST00000532598.1
olfactory receptor family 51 subfamily C member 1 pseudogene
olfactory receptor family 51 subfamily E member 2
chr20_-_59007807 1.22 ENST00000680386.1
cathepsin Z
chr17_-_43125300 1.21 ENST00000497488.1
ENST00000354071.7
ENST00000489037.1
ENST00000470026.5
ENST00000644555.1
ENST00000586385.5
ENST00000591534.5
ENST00000591849.5
BRCA1 DNA repair associated
chr20_-_1619996 1.18 ENST00000381603.7
ENST00000381605.9
ENST00000279477.11
ENST00000568365.1
ENST00000564763.1
signal regulatory protein beta 1
novel protein, SIRPB1-SIRPD readthrough
chr1_-_47231715 1.16 ENST00000371884.6
TAL bHLH transcription factor 1, erythroid differentiation factor
chr4_-_39977836 1.14 ENST00000303538.13
ENST00000503396.5
PDS5 cohesin associated factor A
chr3_+_42091316 1.12 ENST00000327628.10
trafficking kinesin protein 1
chr17_-_49678074 1.12 ENST00000505581.5
ENST00000504102.6
ENST00000514121.6
ENST00000393328.6
ENST00000509079.6
ENST00000347630.6
speckle type BTB/POZ protein
chr14_+_58298497 1.08 ENST00000348476.7
ENST00000355431.8
ENST00000395168.7
AT-rich interaction domain 4A
chr12_+_66189254 1.08 ENST00000457197.2
interleukin 1 receptor associated kinase 3
chr8_-_25458389 1.06 ENST00000221200.9
potassium channel tetramerization domain containing 9
chr17_+_75093287 1.04 ENST00000538213.6
ENST00000584118.1
solute carrier family 16 member 5
chr1_-_168729187 1.04 ENST00000367817.4
dermatopontin
chr2_-_191013955 1.02 ENST00000409465.5
signal transducer and activator of transcription 1
chr4_-_76007501 0.97 ENST00000264888.6
C-X-C motif chemokine ligand 9
chr7_+_23106267 0.97 ENST00000409689.5
ENST00000410047.1
kelch like family member 7
chr9_-_85741874 0.96 ENST00000357081.8
ENST00000337006.8
ENST00000628899.1
ATP/GTP binding protein 1
chr19_+_40991274 0.91 ENST00000324071.10
cytochrome P450 family 2 subfamily B member 6
chr19_-_54189550 0.87 ENST00000338624.10
ENST00000245615.6
membrane bound O-acyltransferase domain containing 7
chr20_+_64084995 0.87 ENST00000349451.3
opioid related nociceptin receptor 1
chr3_-_158732442 0.83 ENST00000479756.1
ENST00000237696.10
retinoic acid receptor responder 1
chr11_+_15073562 0.82 ENST00000533448.1
ENST00000324229.11
calcitonin related polypeptide beta
chr2_-_77522347 0.81 ENST00000409093.1
ENST00000409884.6
ENST00000409088.3
leucine rich repeat transmembrane neuronal 4
chr1_-_161118024 0.79 ENST00000368010.4
prefoldin subunit 2
chr6_+_167291309 0.79 ENST00000230256.8
unc-93 homolog A
chr17_+_59209867 0.77 ENST00000578922.1
ENST00000300917.10
SMG8 nonsense mediated mRNA decay factor
chr19_+_11239602 0.69 ENST00000252453.12
angiopoietin like 8
chr7_-_44848021 0.69 ENST00000349299.7
ENST00000521529.5
ENST00000350771.7
ENST00000222690.10
ENST00000381124.9
ENST00000437072.5
ENST00000446531.1
ENST00000308153.9
H2A.Z variant histone 2
chr6_+_167291329 0.65 ENST00000366829.2
unc-93 homolog A
chr19_-_6670151 0.64 ENST00000675206.1
TNF superfamily member 14

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.9 26.8 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
7.9 31.5 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
6.9 48.6 GO:1990822 regulation of arginine metabolic process(GO:0000821) basic amino acid transmembrane transport(GO:1990822)
6.5 25.9 GO:1903786 mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
6.2 24.8 GO:0002384 hepatic immune response(GO:0002384)
6.1 18.3 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
5.6 129.0 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
5.6 22.3 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
4.9 34.1 GO:0034201 response to oleic acid(GO:0034201)
4.5 58.0 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
4.4 13.3 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
4.4 22.1 GO:0071727 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
4.3 12.9 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
4.3 17.1 GO:0071918 pyrimidine nucleobase transport(GO:0015855) urea transmembrane transport(GO:0071918) purine nucleobase transmembrane transport(GO:1904823)
3.7 51.7 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
3.3 6.6 GO:0006097 glyoxylate cycle(GO:0006097)
3.3 6.6 GO:0002892 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
3.2 9.7 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
3.2 15.8 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
3.1 9.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
2.9 8.6 GO:2000439 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) negative regulation of eosinophil activation(GO:1902567) positive regulation of monocyte extravasation(GO:2000439)
2.8 13.9 GO:0006741 NADP biosynthetic process(GO:0006741)
2.6 15.7 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
2.2 8.9 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
2.1 6.4 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
2.1 6.3 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
2.1 6.2 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
2.0 6.1 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
1.9 15.6 GO:0001887 selenium compound metabolic process(GO:0001887)
1.9 5.7 GO:1901859 late nucleophagy(GO:0044805) negative regulation of mitochondrial DNA replication(GO:0090298) negative regulation of mitochondrial DNA metabolic process(GO:1901859)
1.9 18.7 GO:0051601 exocyst localization(GO:0051601)
1.8 75.1 GO:0050832 defense response to fungus(GO:0050832)
1.8 27.4 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
1.8 5.3 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
1.7 10.0 GO:1900369 regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
1.7 5.0 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
1.6 4.8 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
1.6 9.3 GO:0048807 female genitalia morphogenesis(GO:0048807)
1.4 4.3 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
1.4 4.1 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
1.3 17.3 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
1.3 3.9 GO:0071373 cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373)
1.2 8.5 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
1.2 3.6 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
1.2 10.6 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
1.1 11.5 GO:0043353 enucleate erythrocyte differentiation(GO:0043353) positive regulation of interferon-gamma biosynthetic process(GO:0045078)
1.1 8.0 GO:0097527 necroptotic signaling pathway(GO:0097527)
1.1 3.3 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
1.0 3.1 GO:2000697 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
1.0 7.2 GO:0061198 fungiform papilla formation(GO:0061198)
1.0 7.9 GO:0043152 induction of bacterial agglutination(GO:0043152)
1.0 42.0 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.9 11.9 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.9 7.8 GO:0061052 negative regulation of cell proliferation involved in contact inhibition(GO:0060244) negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.8 1.5 GO:0002326 B cell lineage commitment(GO:0002326)
0.7 7.4 GO:0006983 ER overload response(GO:0006983)
0.7 13.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.7 3.9 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.6 16.7 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.6 1.8 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.6 1.2 GO:0060374 mast cell differentiation(GO:0060374)
0.6 2.8 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.5 3.2 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.5 12.5 GO:0006907 pinocytosis(GO:0006907)
0.5 10.8 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.5 8.3 GO:0042761 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.5 3.3 GO:0019240 citrulline biosynthetic process(GO:0019240)
0.5 1.4 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
0.4 4.0 GO:0015939 pantothenate metabolic process(GO:0015939)
0.4 2.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.4 17.7 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.4 6.1 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.3 36.0 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.3 7.0 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.3 4.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.3 12.8 GO:0000717 nucleotide-excision repair, DNA duplex unwinding(GO:0000717)
0.3 14.5 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.3 3.8 GO:0070327 thyroid hormone transport(GO:0070327)
0.3 1.4 GO:0045959 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959)
0.3 2.0 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.3 1.1 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.3 1.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.3 1.9 GO:0060331 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.3 2.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 0.5 GO:0038091 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.2 1.2 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.2 5.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 2.6 GO:0021740 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.2 2.8 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.2 2.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 3.6 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.2 0.6 GO:0060003 copper ion export(GO:0060003)
0.2 1.4 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 0.9 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 10.2 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.2 6.0 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.1 0.6 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 4.3 GO:0042772 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.1 2.8 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1 8.5 GO:0050819 negative regulation of coagulation(GO:0050819)
0.1 0.6 GO:0015677 copper ion import(GO:0015677) ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 1.7 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 6.0 GO:0006458 'de novo' protein folding(GO:0006458)
0.1 2.2 GO:0006491 N-glycan processing(GO:0006491)
0.1 1.5 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.1 5.3 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 0.5 GO:0032916 negative regulation of cardiac muscle adaptation(GO:0010616) evasion or tolerance of host defenses by virus(GO:0019049) positive regulation of transforming growth factor beta3 production(GO:0032916) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) negative regulation of lung blood pressure(GO:0061767) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.1 5.0 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 1.4 GO:0019054 modulation by virus of host process(GO:0019054)
0.1 1.1 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 0.2 GO:0060585 positive regulation of the force of heart contraction by chemical signal(GO:0003099) regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 1.7 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 5.5 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.7 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 1.0 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.0 0.3 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.3 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.4 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.2 GO:0097264 self proteolysis(GO:0097264)
0.0 1.8 GO:0016925 protein sumoylation(GO:0016925)
0.0 1.9 GO:0051225 spindle assembly(GO:0051225)
0.0 0.2 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 51.7 GO:0097452 GAIT complex(GO:0097452)
5.0 24.8 GO:0005896 interleukin-6 receptor complex(GO:0005896)
4.4 13.3 GO:0072557 IPAF inflammasome complex(GO:0072557)
3.2 12.9 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
3.2 12.8 GO:0071942 XPC complex(GO:0071942)
2.5 22.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
2.3 15.8 GO:0044530 supraspliceosomal complex(GO:0044530)
1.2 14.4 GO:0005577 fibrinogen complex(GO:0005577)
1.2 9.2 GO:0005827 polar microtubule(GO:0005827)
1.1 18.7 GO:0000145 exocyst(GO:0000145)
0.9 2.8 GO:0032426 stereocilium tip(GO:0032426)
0.9 19.9 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.7 7.0 GO:0031595 nuclear proteasome complex(GO:0031595)
0.7 3.9 GO:0001940 male pronucleus(GO:0001940)
0.6 23.4 GO:1904724 tertiary granule lumen(GO:1904724)
0.5 112.7 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.4 45.0 GO:0043195 terminal bouton(GO:0043195)
0.4 4.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.4 6.3 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.4 8.0 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.4 7.2 GO:0016580 Sin3 complex(GO:0016580)
0.3 37.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.3 5.3 GO:0097225 sperm midpiece(GO:0097225)
0.3 26.3 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.3 1.4 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
0.2 7.8 GO:0071437 invadopodium(GO:0071437)
0.2 4.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 7.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 3.6 GO:0001891 phagocytic cup(GO:0001891)
0.2 1.9 GO:0005641 nuclear envelope lumen(GO:0005641)
0.2 2.4 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 3.3 GO:0036019 endolysosome(GO:0036019)
0.1 20.1 GO:0016605 PML body(GO:0016605)
0.1 22.5 GO:0032993 protein-DNA complex(GO:0032993)
0.1 11.3 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 2.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 12.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 45.1 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 1.8 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.8 GO:0016272 prefoldin complex(GO:0016272)
0.1 5.3 GO:0016234 inclusion body(GO:0016234)
0.1 9.7 GO:0005901 caveola(GO:0005901)
0.1 7.4 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 2.2 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 2.8 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.1 6.6 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.1 3.8 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 4.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 8.6 GO:0043204 perikaryon(GO:0043204)
0.1 19.2 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 4.9 GO:0031225 anchored component of membrane(GO:0031225)
0.1 26.3 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.1 3.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 0.5 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 8.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 10.4 GO:0010008 endosome membrane(GO:0010008)
0.0 5.5 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 49.8 GO:0005615 extracellular space(GO:0005615)
0.0 6.0 GO:0005840 ribosome(GO:0005840)
0.0 6.5 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 16.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 2.7 GO:0044217 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 1.1 GO:1904115 axon cytoplasm(GO:1904115)
0.0 32.7 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 3.4 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 2.2 GO:0005802 trans-Golgi network(GO:0005802)
0.0 10.2 GO:0005815 microtubule organizing center(GO:0005815)
0.0 1.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 1.1 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 1.2 GO:0030667 secretory granule membrane(GO:0030667)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
14.5 58.0 GO:0004074 biliverdin reductase activity(GO:0004074)
12.9 129.0 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
6.4 19.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
5.7 17.1 GO:0015265 urea channel activity(GO:0015265)
5.6 22.3 GO:0002060 purine nucleobase binding(GO:0002060)
5.5 22.1 GO:0016019 peptidoglycan receptor activity(GO:0016019)
5.2 31.5 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672)
4.0 48.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
3.9 27.5 GO:0001849 complement component C1q binding(GO:0001849)
3.9 15.7 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
3.5 17.3 GO:1990254 keratin filament binding(GO:1990254)
3.1 9.2 GO:0031208 POZ domain binding(GO:0031208)
2.9 8.6 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
2.8 8.3 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
2.4 9.7 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
2.2 37.6 GO:0001222 transcription corepressor binding(GO:0001222)
2.2 6.6 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
1.8 12.5 GO:0030492 hemoglobin binding(GO:0030492)
1.8 5.3 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
1.5 6.1 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
1.5 4.5 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
1.5 10.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
1.4 4.3 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
1.4 34.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
1.3 8.0 GO:0043120 tumor necrosis factor binding(GO:0043120)
1.3 51.7 GO:0008143 poly(A) binding(GO:0008143)
1.3 10.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
1.2 6.2 GO:0016841 ammonia-lyase activity(GO:0016841)
1.2 19.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
1.2 4.9 GO:0017159 pantetheine hydrolase activity(GO:0017159)
1.2 16.7 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.2 5.8 GO:0005138 interleukin-6 receptor binding(GO:0005138)
1.1 3.4 GO:0070052 collagen V binding(GO:0070052)
1.1 3.3 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
1.1 13.3 GO:0050700 CARD domain binding(GO:0050700)
1.1 11.9 GO:0046790 virion binding(GO:0046790)
1.1 6.3 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.9 5.7 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.9 2.8 GO:0032427 GBD domain binding(GO:0032427)
0.9 3.7 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.8 3.3 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.8 2.4 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.8 7.0 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.7 26.1 GO:0001221 transcription cofactor binding(GO:0001221)
0.7 3.3 GO:0004522 ribonuclease A activity(GO:0004522)
0.6 31.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.6 6.4 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.6 2.5 GO:0051748 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
0.6 23.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.6 9.3 GO:0019841 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.5 5.3 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.5 14.3 GO:0003951 NAD+ kinase activity(GO:0003951)
0.5 8.1 GO:0070513 death domain binding(GO:0070513)
0.4 7.2 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.4 2.8 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.4 3.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.4 1.5 GO:0070644 vitamin D response element binding(GO:0070644)
0.4 11.5 GO:0008301 DNA binding, bending(GO:0008301)
0.4 43.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.3 12.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.3 8.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.3 4.3 GO:0008494 translation activator activity(GO:0008494)
0.3 22.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.3 14.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.3 2.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 0.6 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.3 5.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.3 9.2 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.3 1.8 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 1.7 GO:0070569 uridylyltransferase activity(GO:0070569)
0.2 1.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 12.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.2 0.9 GO:0001626 nociceptin receptor activity(GO:0001626)
0.2 1.9 GO:0050692 DBD domain binding(GO:0050692)
0.2 10.9 GO:0016504 peptidase activator activity(GO:0016504)
0.2 1.4 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.2 2.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 0.5 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.2 0.6 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 38.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 7.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 0.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 13.1 GO:0000149 SNARE binding(GO:0000149)
0.1 1.8 GO:0032183 SUMO transferase activity(GO:0019789) SUMO binding(GO:0032183)
0.1 6.1 GO:0004520 endodeoxyribonuclease activity(GO:0004520)
0.1 0.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.5 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.1 2.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 5.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 7.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.1 41.8 GO:0003779 actin binding(GO:0003779)
0.1 3.9 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.1 1.1 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.1 GO:0050811 GABA receptor binding(GO:0050811)
0.0 2.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 24.1 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 5.9 GO:0001047 core promoter binding(GO:0001047)
0.0 1.1 GO:0042056 chemoattractant activity(GO:0042056)
0.0 3.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 4.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.4 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 1.1 GO:0004407 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 2.8 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 1.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 4.1 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 1.2 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 2.2 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 24.8 ST STAT3 PATHWAY STAT3 Pathway
1.1 31.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.7 25.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.5 27.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.4 26.5 PID AURORA B PATHWAY Aurora B signaling
0.4 7.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.4 22.8 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.4 3.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.4 13.3 PID AURORA A PATHWAY Aurora A signaling
0.3 14.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.3 9.7 PID S1P S1P1 PATHWAY S1P1 pathway
0.3 14.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.3 6.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3 5.0 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.3 8.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 6.3 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.2 8.1 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.2 4.5 PID IL1 PATHWAY IL1-mediated signaling events
0.2 10.8 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.2 12.0 PID BMP PATHWAY BMP receptor signaling
0.2 15.7 PID IL12 2PATHWAY IL12-mediated signaling events
0.2 3.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 11.9 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 7.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 1.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 3.9 PID ATM PATHWAY ATM pathway
0.1 1.4 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 6.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 1.0 PID IL23 PATHWAY IL23-mediated signaling events
0.1 4.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 4.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 4.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 22.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.1 2.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 3.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.4 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 61.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
2.0 37.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
1.9 34.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
1.7 22.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
1.6 27.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
1.4 13.9 REACTOME BETA DEFENSINS Genes involved in Beta defensins
1.3 17.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
1.1 17.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.9 11.9 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.9 44.9 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.7 13.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.6 14.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.5 28.7 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.5 17.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.5 37.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.5 29.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.5 11.0 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.4 22.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.4 12.8 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.4 4.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.3 3.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.3 8.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.3 4.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.3 7.9 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.2 34.4 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.2 5.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 5.0 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.2 5.8 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 6.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 3.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.2 3.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 3.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 3.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 6.6 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.1 10.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.1 19.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.1 8.2 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 2.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 2.6 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 1.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 1.4 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.1 12.5 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 5.3 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 1.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 5.8 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 1.2 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 3.9 REACTOME SIGNALING BY PDGF Genes involved in Signaling by PDGF
0.0 1.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 1.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.8 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events