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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for CEBPG

Z-value: 2.27

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Transcription factors associated with CEBPG

Gene Symbol Gene ID Gene Info
CEBPG
ENSG00000153879.9 CEBPG

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPGhg38_v1_chr19_+_33373694_33373826,
hg38_v1_chr19_+_33374312_33374348		-0.371.6e-08Click!

Activity profile of CEBPG motif

Sorted Z-values of CEBPG motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPG

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr11_-_5227063 20.10 ENST00000335295.4
ENST00000485743.1
ENST00000647020.1
HBB
hemoglobin subunit beta
chr3_+_186717348 13.32 ENST00000447445.1
ENST00000287611.8
ENST00000644859.2
KNG1
kininogen 1
chr3_+_101849505 12.33 ENST00000326151.9
ENST00000326172.9
NFKBIZ
NFKB inhibitor zeta
chr12_-_12338674 10.43 ENST00000545735.1
MANSC1
MANSC domain containing 1
chr12_+_7060676 9.64 ENST00000617865.4
ENST00000402681.7
ENST00000360817.10
C1S
complement C1s
chr3_+_186613052 9.39 ENST00000411641.7
ENST00000273784.5
AHSG
alpha 2-HS glycoprotein
chr19_-_20661563 8.13 ENST00000601440.6
ENST00000291750.6
ENST00000595094.1
ZNF626
ENSG00000269110.1
zinc finger protein 626
novel transcript
chr16_+_72063226 7.97 ENST00000540303.7
ENST00000356967.6
ENST00000561690.1
HPR
haptoglobin-related protein
chr16_+_72054477 7.53 ENST00000355906.10
ENST00000570083.5
ENST00000228226.12
ENST00000398131.6
ENST00000569639.5
ENST00000564499.5
ENST00000357763.8
ENST00000613898.1
ENST00000562526.5
ENST00000565574.5
ENST00000568417.6
HP
haptoglobin
chr19_-_20661507 7.51 ENST00000612591.4
ENST00000595405.1
ZNF626
zinc finger protein 626
chr4_+_73404255 7.43 ENST00000621628.4
ENST00000621085.4
ENST00000415165.6
ENST00000295897.9
ENST00000503124.5
ENST00000509063.5
ENST00000401494.7
ALB
albumin
chr4_-_687325 6.98 ENST00000503156.5
SLC49A3
solute carrier family 49 member 3
chr9_+_114323098 6.87 ENST00000259396.9
ORM1
orosomucoid 1
chr2_-_21044063 6.58 ENST00000233242.5
APOB
apolipoprotein B
chr6_+_31927683 6.48 ENST00000456570.5
ENSG00000244255.5
novel complement component 2 (C2) and complement factor B (CFB) protein
chr4_+_70383123 6.06 ENST00000304915.8
SMR3B
submaxillary gland androgen regulated protein 3B
chr17_-_69150062 6.03 ENST00000522787.5
ENST00000521538.5
ABCA10
ATP binding cassette subfamily A member 10
chr14_-_69797232 5.82 ENST00000216540.5
SLC10A1
solute carrier family 10 member 1
chr9_+_128149447 5.58 ENST00000277480.7
ENST00000372998.1
LCN2
lipocalin 2
chr16_+_6019585 5.48 ENST00000547372.5
RBFOX1
RNA binding fox-1 homolog 1
chr11_+_18266254 5.38 ENST00000532858.5
ENST00000649195.1
ENST00000356524.9
ENST00000405158.2
SAA1
serum amyloid A1
chr1_-_153348825 5.31 ENST00000368739.3
ENST00000359650.10
PGLYRP4
peptidoglycan recognition protein 4
chr17_-_66229380 4.73 ENST00000205948.11
APOH
apolipoprotein H
chr7_+_22727147 4.40 ENST00000426291.5
ENST00000401651.5
ENST00000258743.10
ENST00000407492.5
ENST00000401630.7
ENST00000406575.1
IL6
interleukin 6
chr1_-_161307420 4.40 ENST00000491222.5
ENST00000672287.2
MPZ
myelin protein zero
chrX_+_47078434 4.35 ENST00000397180.6
RGN
regucalcin
chr12_-_114403898 4.31 ENST00000526441.1
TBX5
T-box transcription factor 5
chr13_-_46105009 4.27 ENST00000439329.5
ENST00000674625.1
ENST00000181383.10
CPB2
carboxypeptidase B2
chr16_+_6019016 4.24 ENST00000550418.6
RBFOX1
RNA binding fox-1 homolog 1
chrX_+_47078380 4.19 ENST00000352078.8
RGN
regucalcin
chr3_-_194351290 4.13 ENST00000429275.1
ENST00000323830.4
CPN2
carboxypeptidase N subunit 2
chr3_-_49689053 4.12 ENST00000449682.2
MST1
macrophage stimulating 1
chr6_+_31927486 4.09 ENST00000442278.6
C2
complement C2
chr6_+_31927703 4.06 ENST00000418949.6
ENST00000299367.10
ENST00000383177.7
ENST00000477310.1
C2
ENSG00000244255.5
complement C2
novel complement component 2 (C2) and complement factor B (CFB) protein
chr22_-_30505650 4.05 ENST00000381982.3
ENST00000255858.12
SEC14L4
SEC14 like lipid binding 4
chr3_-_42264887 3.99 ENST00000334681.9
CCK
cholecystokinin
chrX_+_139530730 3.91 ENST00000218099.7
F9
coagulation factor IX
chr1_+_196774813 3.85 ENST00000471440.6
ENST00000391985.7
ENST00000617219.1
ENST00000367425.9
CFHR3
complement factor H related 3
chr1_+_111227610 3.83 ENST00000369744.6
CHI3L2
chitinase 3 like 2
chr6_-_134950081 3.82 ENST00000367847.2
ENST00000265605.7
ENST00000367845.6
ALDH8A1
aldehyde dehydrogenase 8 family member A1
chr10_-_68332914 3.78 ENST00000358769.7
ENST00000495025.2
PBLD
phenazine biosynthesis like protein domain containing
chr16_+_6019071 3.75 ENST00000547605.5
ENST00000553186.5
RBFOX1
RNA binding fox-1 homolog 1
chr1_+_111227699 3.57 ENST00000369748.9
CHI3L2
chitinase 3 like 2
chr4_+_70360751 3.54 ENST00000226460.5
SMR3A
submaxillary gland androgen regulated protein 3A
chr8_-_6877928 3.44 ENST00000297439.4
DEFB1
defensin beta 1
chr12_-_10453330 3.39 ENST00000347831.9
ENST00000359151.8
KLRC1
killer cell lectin like receptor C1
chr3_-_48088800 3.35 ENST00000423088.5
MAP4
microtubule associated protein 4
chr15_-_34337462 3.25 ENST00000676379.1
SLC12A6
solute carrier family 12 member 6
chr4_+_174918400 3.21 ENST00000404450.8
ENST00000514159.1
ADAM29
ADAM metallopeptidase domain 29
chr19_+_54906140 3.14 ENST00000291890.9
ENST00000598576.5
ENST00000594765.5
ENST00000350790.9
ENST00000338835.9
ENST00000357397.5
NCR1
natural cytotoxicity triggering receptor 1
chr4_+_174918355 3.11 ENST00000505141.5
ENST00000359240.7
ENST00000615367.4
ENST00000445694.5
ENST00000618444.1
ADAM29
ADAM metallopeptidase domain 29
chr5_-_122078249 3.09 ENST00000231004.5
LOX
lysyl oxidase
chr1_+_244969869 3.08 ENST00000366523.5
EFCAB2
EF-hand calcium binding domain 2
chr1_-_113887574 3.07 ENST00000393316.8
BCL2L15
BCL2 like 15
chr8_-_144060681 3.05 ENST00000618853.5
OPLAH
5-oxoprolinase, ATP-hydrolysing
chr11_-_18236795 3.02 ENST00000278222.7
SAA4
serum amyloid A4, constitutive
chr6_+_131135408 3.00 ENST00000431975.7
ENST00000683794.1
AKAP7
A-kinase anchoring protein 7
chr1_+_196888014 2.96 ENST00000367416.6
ENST00000608469.6
ENST00000251424.8
ENST00000367418.2
CFHR4
complement factor H related 4
chr3_-_149221811 2.80 ENST00000455472.3
ENST00000264613.11
CP
ceruloplasmin
chrX_+_1336585 2.75 ENST00000381469.7
IL3RA
interleukin 3 receptor subunit alpha
chr7_-_138755892 2.64 ENST00000644341.1
ENST00000478480.2
ATP6V0A4
ATPase H+ transporting V0 subunit a4
chr17_-_41612757 2.54 ENST00000301653.9
ENST00000593067.1
KRT16
keratin 16
chr10_-_68332878 2.48 ENST00000309049.8
PBLD
phenazine biosynthesis like protein domain containing
chr3_+_178536205 2.45 ENST00000420517.6
KCNMB2
potassium calcium-activated channel subfamily M regulatory beta subunit 2
chr4_+_95840084 2.44 ENST00000295266.6
PDHA2
pyruvate dehydrogenase E1 subunit alpha 2
chr11_-_102798148 2.29 ENST00000315274.7
MMP1
matrix metallopeptidase 1
chr12_-_52680398 2.29 ENST00000252244.3
KRT1
keratin 1
chr1_+_172420681 2.26 ENST00000367727.9
C1orf105
chromosome 1 open reading frame 105
chr5_+_50667405 2.23 ENST00000505554.5
PARP8
poly(ADP-ribose) polymerase family member 8
chr19_+_48755512 2.09 ENST00000593756.6
FGF21
fibroblast growth factor 21
chr8_-_7018295 2.09 ENST00000327857.7
DEFA3
defensin alpha 3
chr4_+_70734419 2.05 ENST00000502653.5
RUFY3
RUN and FYVE domain containing 3
chr5_-_146878720 2.01 ENST00000394411.9
ENST00000453001.5
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr8_-_120811988 2.00 ENST00000517992.2
SNTB1
syntrophin beta 1
chr11_-_123741614 1.92 ENST00000526252.5
ENST00000530393.6
ENST00000533463.5
ENST00000336139.8
ENST00000529691.1
ENST00000528306.5
ZNF202
zinc finger protein 202
chr11_-_61920267 1.88 ENST00000531922.2
ENST00000301773.9
RAB3IL1
RAB3A interacting protein like 1
chr2_+_102104563 1.81 ENST00000409589.5
ENST00000409329.5
IL1R1
interleukin 1 receptor type 1
chr5_-_146878595 1.79 ENST00000394409.7
PPP2R2B
protein phosphatase 2 regulatory subunit Bbeta
chr1_+_99646025 1.71 ENST00000263174.9
ENST00000605497.5
ENST00000615664.1
PALMD
palmdelphin
chr20_+_56412393 1.68 ENST00000679529.1
CASS4
Cas scaffold protein family member 4
chr16_-_33845229 1.66 ENST00000569103.2
IGHV3OR16-17
immunoglobulin heavy variable 3/OR16-17 (non-functional)
chr12_+_111034136 1.65 ENST00000261726.11
CUX2
cut like homeobox 2
chr1_-_54801161 1.64 ENST00000371274.8
TTC22
tetratricopeptide repeat domain 22
chr15_-_34336749 1.61 ENST00000397707.6
ENST00000560611.5
SLC12A6
solute carrier family 12 member 6
chr3_+_178536407 1.61 ENST00000452583.6
KCNMB2
potassium calcium-activated channel subfamily M regulatory beta subunit 2
chrX_+_110520312 1.56 ENST00000602699.1
TDGF1P3
teratocarcinoma-derived growth factor 1 pseudogene 3
chr21_-_36480060 1.47 ENST00000399137.5
CLDN14
claudin 14
chr6_-_132734692 1.45 ENST00000509351.5
ENST00000417437.6
ENST00000423615.6
ENST00000427187.6
ENST00000414302.7
ENST00000367927.9
ENST00000450865.2
VNN3
vanin 3
chr21_-_36480117 1.43 ENST00000399135.6
CLDN14
claudin 14
chr8_+_42697339 1.41 ENST00000289957.3
ENST00000534391.1
CHRNB3
cholinergic receptor nicotinic beta 3 subunit
chr11_-_35360050 1.40 ENST00000644868.1
ENST00000643454.1
ENST00000646080.1
SLC1A2
solute carrier family 1 member 2
chr19_+_48756067 1.38 ENST00000222157.5
FGF21
fibroblast growth factor 21
chr10_+_18340821 1.36 ENST00000612743.1
ENST00000612134.4
CACNB2
calcium voltage-gated channel auxiliary subunit beta 2
chr14_-_80211472 1.35 ENST00000557125.1
ENST00000438257.9
ENST00000422005.7
DIO2
iodothyronine deiodinase 2
chr15_-_74203172 1.33 ENST00000616000.4
STRA6
signaling receptor and transporter of retinol STRA6
chr19_+_47035300 1.31 ENST00000439365.6
ENST00000594670.1
NPAS1
neuronal PAS domain protein 1
chr4_+_69931066 1.30 ENST00000246891.9
CSN1S1
casein alpha s1
chr20_+_56412112 1.29 ENST00000360314.7
CASS4
Cas scaffold protein family member 4
chr9_-_133121228 1.28 ENST00000372050.8
RALGDS
ral guanine nucleotide dissociation stimulator
chr11_+_26188836 1.28 ENST00000672621.1
ANO3
anoctamin 3
chr11_-_102705737 1.24 ENST00000260229.5
MMP27
matrix metallopeptidase 27
chr20_+_56412249 1.22 ENST00000679887.1
ENST00000434344.2
CASS4
Cas scaffold protein family member 4
chr3_+_73061659 1.22 ENST00000533473.1
EBLN2
endogenous Bornavirus like nucleoprotein 2
chr21_+_42199686 1.21 ENST00000398457.6
ABCG1
ATP binding cassette subfamily G member 1
chr12_-_95996302 1.16 ENST00000261208.8
ENST00000538703.5
ENST00000541929.5
HAL
histidine ammonia-lyase
chr1_-_54801290 1.14 ENST00000371276.9
TTC22
tetratricopeptide repeat domain 22
chr19_+_50418930 1.14 ENST00000439922.6
ENST00000595883.6
ENST00000597855.5
ENST00000596074.5
ENST00000594685.1
ENST00000270632.7
SPIB
Spi-B transcription factor
chrX_+_136205982 1.00 ENST00000628568.1
FHL1
four and a half LIM domains 1
chr2_-_89010515 0.93 ENST00000493819.1
IGKV1-9
immunoglobulin kappa variable 1-9
chr3_+_157436842 0.91 ENST00000295927.4
PTX3
pentraxin 3
chrX_-_52517213 0.90 ENST00000375616.5
XAGE1B
X antigen family member 1B
chrX_-_100874209 0.90 ENST00000372964.5
ENST00000217885.5
NOX1
NADPH oxidase 1
chrX_-_74614612 0.87 ENST00000349225.2
ENST00000332687.11
RLIM
ring finger protein, LIM domain interacting
chr18_+_34709356 0.86 ENST00000585446.1
ENST00000681241.1
DTNA
dystrobrevin alpha
chr10_+_18340699 0.84 ENST00000377329.10
CACNB2
calcium voltage-gated channel auxiliary subunit beta 2
chr4_-_118352967 0.80 ENST00000296498.3
PRSS12
serine protease 12
chr7_-_82443766 0.78 ENST00000356860.8
CACNA2D1
calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr21_+_37420299 0.77 ENST00000455097.6
ENST00000643854.1
ENST00000645424.1
ENST00000642309.1
ENST00000645774.1
ENST00000398956.2
DYRK1A
dual specificity tyrosine phosphorylation regulated kinase 1A
chr19_+_2476118 0.73 ENST00000215631.9
ENST00000587345.1
GADD45B
growth arrest and DNA damage inducible beta
chr7_-_82443715 0.72 ENST00000356253.9
ENST00000423588.1
CACNA2D1
calcium voltage-gated channel auxiliary subunit alpha2delta 1
chr13_+_29428603 0.71 ENST00000380808.6
MTUS2
microtubule associated scaffold protein 2
chr1_-_47190013 0.71 ENST00000294338.7
PDZK1IP1
PDZK1 interacting protein 1
chr11_+_76782250 0.66 ENST00000533752.1
ENST00000612930.1
TSKU
tsukushi, small leucine rich proteoglycan
chr19_-_18538371 0.64 ENST00000596015.1
FKBP8
FKBP prolyl isomerase 8
chr10_-_90921079 0.58 ENST00000371697.4
ANKRD1
ankyrin repeat domain 1
chr9_-_114930508 0.54 ENST00000223795.3
ENST00000618336.4
TNFSF8
TNF superfamily member 8
chr14_+_39233908 0.54 ENST00000280082.4
MIA2
MIA SH3 domain ER export factor 2
chr9_+_133534807 0.54 ENST00000393060.1
ADAMTSL2
ADAMTS like 2
chr2_-_182427014 0.54 ENST00000409365.5
ENST00000351439.9
PDE1A
phosphodiesterase 1A
chr1_-_179143044 0.51 ENST00000504405.5
ENST00000512653.5
ENST00000344730.7
ABL2
ABL proto-oncogene 2, non-receptor tyrosine kinase
chr22_-_30471986 0.41 ENST00000401751.5
ENST00000402286.5
ENST00000403066.5
ENST00000215812.9
SEC14L3
SEC14 like lipid binding 3
chr6_-_30742486 0.38 ENST00000438162.5
ENST00000454845.1
FLOT1
flotillin 1
chr7_-_8236878 0.36 ENST00000401396.5
ENST00000317367.9
ICA1
islet cell autoantigen 1
chr9_+_113150991 0.32 ENST00000259392.8
SLC31A2
solute carrier family 31 member 2
chr19_-_6670151 0.28 ENST00000675206.1
TNFSF14
TNF superfamily member 14
chr8_+_96584920 0.25 ENST00000521590.5
SDC2
syndecan 2
chr14_-_106117159 0.22 ENST00000390601.3
IGHV3-11
immunoglobulin heavy variable 3-11
chr1_+_154405326 0.14 ENST00000368485.8
IL6R
interleukin 6 receptor
chr19_-_6670117 0.13 ENST00000245912.7
TNFSF14
TNF superfamily member 14
chr6_-_132618178 0.07 ENST00000275191.2
TAAR2
trace amine associated receptor 2
chr18_-_28036585 0.06 ENST00000399380.7
CDH2
cadherin 2
chr16_-_57186014 0.02 ENST00000566584.5
ENST00000566481.5
ENST00000566077.5
ENST00000564108.5
ENST00000309137.13
ENST00000565458.5
ENST00000566681.1
ENST00000567439.5
PSME3IP1
proteasome activator subunit 3 interacting protein 1
chr1_+_59296971 0.01 ENST00000371218.8
FGGY
FGGY carbohydrate kinase domain containing

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
6.7 20.1 GO:0030185 nitric oxide transport(GO:0030185)
2.5 7.5 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
2.5 7.4 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
2.1 8.5 GO:1903610 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
2.1 6.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
1.8 5.3 GO:0051710 regulation of cytolysis in other organism(GO:0051710)
1.4 4.3 GO:0003218 cardiac left ventricle formation(GO:0003218)
1.1 3.4 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
1.1 5.6 GO:0010046 response to mycotoxin(GO:0010046) iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.1 4.4 GO:1990637 response to prolactin(GO:1990637)
1.1 4.3 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
1.0 11.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.9 6.6 GO:0006642 triglyceride mobilization(GO:0006642)
0.9 2.7 GO:0038156 interleukin-3-mediated signaling pathway(GO:0038156)
0.9 3.5 GO:1904640 response to methionine(GO:1904640)
0.8 22.0 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.7 8.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.7 4.9 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.7 7.4 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.6 1.8 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
0.6 6.9 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.6 3.3 GO:0051012 microtubule sliding(GO:0051012)
0.4 1.3 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.4 3.8 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.4 1.2 GO:0009720 detection of hormone stimulus(GO:0009720)
0.4 1.2 GO:0019557 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.4 3.7 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.4 9.4 GO:0006907 pinocytosis(GO:0006907)
0.3 4.0 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.3 0.9 GO:1903015 regulation of exo-alpha-sialidase activity(GO:1903015)
0.3 0.9 GO:1990451 cellular stress response to acidic pH(GO:1990451)
0.3 4.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.3 3.1 GO:0048251 elastic fiber assembly(GO:0048251)
0.2 1.3 GO:0061143 alveolar primary septum development(GO:0061143)
0.2 2.6 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 14.2 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.2 4.1 GO:0005513 detection of calcium ion(GO:0005513)
0.2 0.7 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.2 3.8 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.1 4.4 GO:0098743 cell aggregation(GO:0098743)
0.1 2.5 GO:0051546 keratinocyte migration(GO:0051546)
0.1 2.1 GO:0002227 innate immune response in mucosa(GO:0002227)
0.1 2.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 4.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 5.4 GO:0048246 macrophage chemotaxis(GO:0048246)
0.1 1.4 GO:0015939 pantothenate metabolic process(GO:0015939)
0.1 1.4 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 3.1 GO:0006825 copper ion transport(GO:0006825)
0.1 0.4 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 1.4 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1 2.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.9 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.1 3.1 GO:0042269 regulation of natural killer cell mediated cytotoxicity(GO:0042269)
0.1 0.5 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.1 1.7 GO:0007614 short-term memory(GO:0007614)
0.1 3.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 1.3 GO:0060746 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.1 2.3 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.1 7.3 GO:0030449 regulation of complement activation(GO:0030449) regulation of protein activation cascade(GO:2000257)
0.0 2.3 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.3 GO:0008218 bioluminescence(GO:0008218)
0.0 0.8 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 3.0 GO:0050918 positive chemotaxis(GO:0050918)
0.0 0.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 2.1 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.6 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.0 1.2 GO:0030574 collagen catabolic process(GO:0030574)
0.0 1.0 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 5.0 GO:0006869 lipid transport(GO:0006869)
0.0 0.5 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
6.9 27.6 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.9 6.6 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.8 4.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.7 8.0 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.5 13.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.4 4.0 GO:0043203 axon hillock(GO:0043203)
0.3 37.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.3 2.6 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 2.4 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.2 3.4 GO:0097225 sperm midpiece(GO:0097225)
0.2 3.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 1.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 22.7 GO:0072562 blood microparticle(GO:0072562)
0.1 3.8 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 3.1 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 3.0 GO:0071437 invadopodium(GO:0071437)
0.1 12.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 2.0 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 6.3 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.8 GO:0043083 synaptic cleft(GO:0043083)
0.0 1.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 3.3 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0 3.1 GO:0005581 collagen trimer(GO:0005581)
0.0 13.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.4 GO:0030673 axolemma(GO:0030673)
0.0 4.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 8.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 2.5 GO:0005882 intermediate filament(GO:0005882)
0.0 26.7 GO:0005615 extracellular space(GO:0005615)
0.0 2.8 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 3.2 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.3 GO:0005903 brush border(GO:0005903)
0.0 1.5 GO:0055037 recycling endosome(GO:0055037)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 35.6 GO:0030492 hemoglobin binding(GO:0030492)
2.1 8.5 GO:0004341 gluconolactonase activity(GO:0004341)
1.6 6.6 GO:0035473 lipase binding(GO:0035473)
1.5 5.8 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
1.2 5.0 GO:0016019 peptidoglycan receptor activity(GO:0016019)
1.2 4.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
1.1 3.4 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
1.0 3.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.9 2.7 GO:0004912 interleukin-3 receptor activity(GO:0004912)
0.7 3.4 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.7 7.4 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.6 2.4 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.5 3.0 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.5 7.4 GO:0015643 toxic substance binding(GO:0015643)
0.5 1.8 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
0.4 4.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.4 1.4 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.4 2.8 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.3 4.9 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.3 3.8 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.3 1.2 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.3 0.9 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.3 8.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.3 1.4 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.3 23.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2 1.2 GO:0016841 ammonia-lyase activity(GO:0016841)
0.2 3.7 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.2 8.4 GO:0042056 chemoattractant activity(GO:0042056)
0.2 0.6 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 2.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.9 GO:0001849 complement component C1q binding(GO:0001849)
0.1 3.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 4.1 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.5 GO:0050436 microfibril binding(GO:0050436)
0.1 4.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 29.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 2.6 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 1.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 3.0 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 7.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 1.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.8 GO:0048156 tau protein binding(GO:0048156)
0.0 3.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 6.9 GO:0016853 isomerase activity(GO:0016853)
0.0 1.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 5.6 GO:0005506 iron ion binding(GO:0005506)
0.0 10.8 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.3 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 1.7 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.0 0.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 3.1 GO:0030165 PDZ domain binding(GO:0030165)
0.0 3.0 GO:0005319 lipid transporter activity(GO:0005319)
0.0 1.1 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 12.8 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 3.1 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 15.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.3 13.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.2 5.1 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 9.4 PID BMP PATHWAY BMP receptor signaling
0.1 7.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 22.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.8 PID ATR PATHWAY ATR signaling pathway
0.1 2.7 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.8 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.0 2.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 2.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.9 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.9 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.3 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 17.8 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.8 13.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.7 17.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.3 7.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 6.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 4.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 3.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 5.4 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 4.3 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 20.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 2.5 REACTOME DEFENSINS Genes involved in Defensins
0.1 5.4 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.1 4.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 2.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 2.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 2.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 2.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 3.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 4.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation