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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for CLOCK
Z-value: 13.78
Motif logo
Transcription factors associated with CLOCK
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
CLOCK
|
ENSG00000134852.15 | CLOCK |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CLOCK | hg38_v1_chr4_-_55546900_55546919 | 0.01 | 9.1e-01 | Click! |
Activity profile of CLOCK motif
Sorted Z-values of CLOCK motif
Network of associatons between targets according to the STRING database.
First level regulatory network of CLOCK
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 32.3 | 96.9 | GO:0002368 | B cell cytokine production(GO:0002368) |
| 27.8 | 139.0 | GO:0033387 | putrescine biosynthetic process from ornithine(GO:0033387) |
| 21.3 | 85.3 | GO:0018106 | peptidyl-histidine phosphorylation(GO:0018106) |
| 19.3 | 115.5 | GO:0019264 | glycine biosynthetic process from serine(GO:0019264) |
| 17.7 | 17.7 | GO:0018171 | peptidyl-cysteine oxidation(GO:0018171) |
| 14.5 | 72.4 | GO:1904637 | response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637) |
| 13.2 | 118.6 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 13.1 | 52.5 | GO:2000259 | positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259) |
| 12.8 | 153.8 | GO:1905098 | regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495) negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) |
| 12.6 | 37.7 | GO:0046452 | dihydrofolate metabolic process(GO:0046452) |
| 11.0 | 98.8 | GO:0031536 | regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994) positive regulation of exit from mitosis(GO:0031536) |
| 9.5 | 66.4 | GO:0046985 | histone H4-R3 methylation(GO:0043985) negative regulation of megakaryocyte differentiation(GO:0045653) positive regulation of hemoglobin biosynthetic process(GO:0046985) |
| 9.1 | 45.4 | GO:1904764 | negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764) |
| 8.8 | 43.8 | GO:0015862 | uridine transport(GO:0015862) |
| 8.5 | 33.9 | GO:0042264 | peptidyl-aspartic acid hydroxylation(GO:0042264) |
| 7.7 | 30.8 | GO:0000961 | negative regulation of mitochondrial RNA catabolic process(GO:0000961) |
| 7.6 | 122.4 | GO:0009113 | purine nucleobase biosynthetic process(GO:0009113) |
| 7.5 | 37.5 | GO:0006546 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 7.2 | 28.6 | GO:2000254 | regulation of male germ cell proliferation(GO:2000254) negative regulation of male germ cell proliferation(GO:2000255) |
| 7.1 | 21.3 | GO:0097698 | telomere maintenance via base-excision repair(GO:0097698) |
| 6.9 | 27.6 | GO:1901165 | negative regulation of MDA-5 signaling pathway(GO:0039534) positive regulation of trophoblast cell migration(GO:1901165) |
| 6.8 | 20.4 | GO:1901388 | regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389) |
| 6.7 | 20.2 | GO:0090149 | mitochondrial membrane fission(GO:0090149) |
| 6.5 | 109.8 | GO:0006089 | lactate metabolic process(GO:0006089) |
| 6.3 | 18.8 | GO:0097252 | oligodendrocyte apoptotic process(GO:0097252) |
| 5.7 | 22.8 | GO:1990928 | response to amino acid starvation(GO:1990928) |
| 5.6 | 16.7 | GO:2000298 | regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298) |
| 5.3 | 15.9 | GO:0000454 | snoRNA guided rRNA pseudouridine synthesis(GO:0000454) |
| 5.1 | 20.2 | GO:0055011 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
| 4.8 | 14.4 | GO:0070407 | oxidation-dependent protein catabolic process(GO:0070407) |
| 4.6 | 13.7 | GO:2000234 | positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234) |
| 4.5 | 18.2 | GO:2000435 | regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435) |
| 4.5 | 49.9 | GO:0006552 | leucine catabolic process(GO:0006552) |
| 4.2 | 33.5 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 4.0 | 16.2 | GO:0046833 | positive regulation of RNA export from nucleus(GO:0046833) |
| 3.9 | 11.8 | GO:1903033 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 3.8 | 26.8 | GO:0008295 | spermidine biosynthetic process(GO:0008295) |
| 3.8 | 19.0 | GO:0006344 | maintenance of chromatin silencing(GO:0006344) |
| 3.8 | 11.4 | GO:0044205 | 'de novo' UMP biosynthetic process(GO:0044205) |
| 3.5 | 17.3 | GO:0070370 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 3.4 | 47.2 | GO:0015074 | DNA integration(GO:0015074) |
| 3.3 | 20.0 | GO:0048254 | snoRNA localization(GO:0048254) |
| 3.3 | 23.1 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 3.2 | 19.2 | GO:0006696 | ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204) |
| 3.2 | 12.7 | GO:0009956 | radial pattern formation(GO:0009956) |
| 3.1 | 9.4 | GO:1901503 | ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503) |
| 3.1 | 40.5 | GO:0045008 | depyrimidination(GO:0045008) |
| 3.1 | 9.2 | GO:0006059 | hexitol metabolic process(GO:0006059) |
| 3.1 | 45.8 | GO:0000338 | protein deneddylation(GO:0000338) |
| 3.0 | 23.8 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
| 2.9 | 26.0 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
| 2.8 | 25.4 | GO:0010835 | regulation of protein ADP-ribosylation(GO:0010835) |
| 2.8 | 11.0 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
| 2.7 | 10.7 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
| 2.6 | 13.2 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) |
| 2.6 | 7.8 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 2.4 | 7.2 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 2.4 | 7.2 | GO:0072425 | signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) |
| 2.3 | 9.3 | GO:0008588 | release of cytoplasmic sequestered NF-kappaB(GO:0008588) |
| 2.3 | 13.8 | GO:0098704 | fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539) |
| 2.2 | 15.6 | GO:0046061 | dATP catabolic process(GO:0046061) |
| 2.2 | 6.6 | GO:0052047 | interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047) |
| 2.2 | 13.0 | GO:0051563 | microglia differentiation(GO:0014004) microglia development(GO:0014005) collateral sprouting in absence of injury(GO:0048669) smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) response to norepinephrine(GO:0071873) cellular response to norepinephrine stimulus(GO:0071874) |
| 2.1 | 12.9 | GO:0006065 | UDP-glucuronate biosynthetic process(GO:0006065) glucose 1-phosphate metabolic process(GO:0019255) |
| 2.0 | 2.0 | GO:0000960 | mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960) |
| 2.0 | 17.7 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 2.0 | 21.5 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 1.9 | 15.4 | GO:1903026 | negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026) |
| 1.9 | 5.7 | GO:0042704 | uterine wall breakdown(GO:0042704) |
| 1.9 | 30.2 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 1.9 | 35.8 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 1.9 | 11.2 | GO:0019509 | L-methionine biosynthetic process from methylthioadenosine(GO:0019509) |
| 1.9 | 13.1 | GO:0006616 | SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616) |
| 1.9 | 29.7 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 1.8 | 5.5 | GO:0070902 | mitochondrial tRNA pseudouridine synthesis(GO:0070902) |
| 1.8 | 12.6 | GO:0033183 | negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915) |
| 1.8 | 21.5 | GO:0006983 | ER overload response(GO:0006983) |
| 1.7 | 12.1 | GO:0046726 | positive regulation by virus of viral protein levels in host cell(GO:0046726) |
| 1.7 | 12.1 | GO:0032328 | alanine transport(GO:0032328) |
| 1.7 | 8.4 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 1.6 | 4.7 | GO:0048817 | negative regulation of hair follicle maturation(GO:0048817) |
| 1.5 | 4.6 | GO:0060577 | subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578) |
| 1.5 | 18.5 | GO:0019388 | galactose catabolic process(GO:0019388) |
| 1.5 | 6.1 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 1.5 | 24.2 | GO:0051085 | chaperone mediated protein folding requiring cofactor(GO:0051085) |
| 1.5 | 112.2 | GO:0070125 | mitochondrial translational elongation(GO:0070125) |
| 1.5 | 4.4 | GO:0036245 | cellular response to menadione(GO:0036245) |
| 1.4 | 34.5 | GO:0031167 | rRNA methylation(GO:0031167) |
| 1.4 | 39.9 | GO:0000470 | maturation of LSU-rRNA(GO:0000470) |
| 1.4 | 8.5 | GO:0006012 | galactose metabolic process(GO:0006012) |
| 1.4 | 4.1 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
| 1.3 | 4.0 | GO:1990519 | pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519) |
| 1.3 | 2.7 | GO:0006286 | base-excision repair, base-free sugar-phosphate removal(GO:0006286) DNA dephosphorylation(GO:0098502) |
| 1.3 | 5.3 | GO:2000393 | negative regulation of lamellipodium morphogenesis(GO:2000393) |
| 1.3 | 53.2 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 1.3 | 7.8 | GO:0010643 | cell communication by chemical coupling(GO:0010643) |
| 1.3 | 21.3 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 1.2 | 13.3 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
| 1.2 | 22.3 | GO:0070831 | basement membrane assembly(GO:0070831) |
| 1.2 | 3.5 | GO:1902498 | regulation of protein autoubiquitination(GO:1902498) |
| 1.1 | 18.7 | GO:0043457 | regulation of cellular respiration(GO:0043457) |
| 1.1 | 5.5 | GO:0007412 | axon target recognition(GO:0007412) |
| 1.1 | 20.5 | GO:0006107 | oxaloacetate metabolic process(GO:0006107) |
| 1.0 | 13.7 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 1.0 | 9.7 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 1.0 | 13.6 | GO:1903441 | protein localization to ciliary membrane(GO:1903441) |
| 1.0 | 23.0 | GO:0035067 | negative regulation of histone acetylation(GO:0035067) |
| 0.9 | 6.5 | GO:0072553 | terminal button organization(GO:0072553) |
| 0.9 | 3.7 | GO:0060528 | secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) |
| 0.9 | 6.4 | GO:2000507 | positive regulation of energy homeostasis(GO:2000507) |
| 0.9 | 23.6 | GO:0006271 | DNA strand elongation involved in DNA replication(GO:0006271) |
| 0.9 | 7.2 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
| 0.9 | 10.8 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
| 0.9 | 3.5 | GO:0090063 | positive regulation of microtubule nucleation(GO:0090063) |
| 0.9 | 13.8 | GO:0006488 | dolichol-linked oligosaccharide biosynthetic process(GO:0006488) |
| 0.9 | 39.2 | GO:0006409 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.8 | 5.8 | GO:0000154 | rRNA modification(GO:0000154) |
| 0.8 | 5.8 | GO:1902570 | protein localization to nucleolus(GO:1902570) |
| 0.8 | 10.9 | GO:0032310 | prostaglandin secretion(GO:0032310) |
| 0.7 | 10.3 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
| 0.7 | 14.6 | GO:0099514 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 0.7 | 5.1 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.7 | 5.0 | GO:0034201 | response to oleic acid(GO:0034201) |
| 0.7 | 40.2 | GO:0018196 | peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279) |
| 0.7 | 6.1 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.7 | 6.1 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.7 | 6.7 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.7 | 3.3 | GO:0006551 | leucine metabolic process(GO:0006551) |
| 0.7 | 29.2 | GO:0097421 | liver regeneration(GO:0097421) |
| 0.7 | 8.5 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
| 0.6 | 6.4 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
| 0.6 | 9.6 | GO:0010452 | histone H3-K36 methylation(GO:0010452) |
| 0.6 | 4.5 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
| 0.6 | 3.1 | GO:0006001 | fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) |
| 0.6 | 2.5 | GO:0046900 | tetrahydrofolylpolyglutamate metabolic process(GO:0046900) |
| 0.6 | 3.1 | GO:0002074 | extraocular skeletal muscle development(GO:0002074) |
| 0.6 | 17.9 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.6 | 8.3 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 0.6 | 15.7 | GO:0018126 | protein hydroxylation(GO:0018126) |
| 0.6 | 3.5 | GO:0090206 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 0.6 | 4.5 | GO:0090160 | Golgi to lysosome transport(GO:0090160) |
| 0.5 | 34.8 | GO:0042274 | ribosomal small subunit biogenesis(GO:0042274) |
| 0.5 | 11.4 | GO:0001765 | membrane raft assembly(GO:0001765) |
| 0.5 | 21.9 | GO:0046856 | phosphatidylinositol dephosphorylation(GO:0046856) |
| 0.5 | 4.2 | GO:0031944 | negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032) |
| 0.5 | 7.8 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 0.5 | 1.5 | GO:0021778 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
| 0.5 | 25.9 | GO:0031648 | protein destabilization(GO:0031648) |
| 0.5 | 3.5 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 0.5 | 1.9 | GO:0036216 | response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109) diapedesis(GO:0050904) |
| 0.5 | 8.0 | GO:0051597 | response to methylmercury(GO:0051597) |
| 0.4 | 39.8 | GO:0006521 | regulation of cellular amino acid metabolic process(GO:0006521) |
| 0.4 | 10.6 | GO:0090190 | positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190) |
| 0.4 | 5.0 | GO:0015939 | pantothenate metabolic process(GO:0015939) |
| 0.4 | 39.5 | GO:0006334 | nucleosome assembly(GO:0006334) |
| 0.4 | 20.9 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.4 | 2.0 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.4 | 30.6 | GO:0045454 | cell redox homeostasis(GO:0045454) |
| 0.4 | 8.5 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
| 0.4 | 1.5 | GO:0097167 | circadian regulation of translation(GO:0097167) |
| 0.4 | 73.6 | GO:0002576 | platelet degranulation(GO:0002576) |
| 0.4 | 19.1 | GO:0043330 | response to exogenous dsRNA(GO:0043330) |
| 0.4 | 2.9 | GO:0045905 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.3 | 17.1 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) peptidyl-proline modification(GO:0018208) |
| 0.3 | 5.2 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
| 0.3 | 6.9 | GO:0018146 | keratan sulfate biosynthetic process(GO:0018146) |
| 0.3 | 1.7 | GO:0000012 | single strand break repair(GO:0000012) |
| 0.3 | 11.2 | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289) |
| 0.3 | 20.7 | GO:0071349 | interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349) |
| 0.3 | 2.1 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
| 0.3 | 7.9 | GO:0006308 | DNA catabolic process(GO:0006308) |
| 0.3 | 8.1 | GO:0006418 | tRNA aminoacylation for protein translation(GO:0006418) |
| 0.3 | 3.1 | GO:0023035 | CD40 signaling pathway(GO:0023035) |
| 0.3 | 9.2 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.3 | 1.0 | GO:0010593 | negative regulation of lamellipodium assembly(GO:0010593) |
| 0.2 | 2.2 | GO:0051549 | positive regulation of keratinocyte migration(GO:0051549) |
| 0.2 | 8.0 | GO:0033198 | response to ATP(GO:0033198) |
| 0.2 | 11.1 | GO:0071392 | cellular response to estradiol stimulus(GO:0071392) |
| 0.2 | 2.3 | GO:0043653 | mitochondrial fragmentation involved in apoptotic process(GO:0043653) |
| 0.2 | 5.7 | GO:0009235 | cobalamin metabolic process(GO:0009235) |
| 0.2 | 2.3 | GO:2001214 | positive regulation of vasculogenesis(GO:2001214) |
| 0.2 | 7.9 | GO:1901998 | toxin transport(GO:1901998) |
| 0.2 | 28.1 | GO:0002062 | chondrocyte differentiation(GO:0002062) |
| 0.2 | 0.7 | GO:0072321 | chaperone-mediated protein transport(GO:0072321) |
| 0.2 | 6.2 | GO:0000717 | nucleotide-excision repair, DNA duplex unwinding(GO:0000717) |
| 0.1 | 2.6 | GO:0070584 | mitochondrion morphogenesis(GO:0070584) |
| 0.1 | 15.1 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 0.1 | 6.1 | GO:0006487 | protein N-linked glycosylation(GO:0006487) |
| 0.1 | 8.7 | GO:0042147 | retrograde transport, endosome to Golgi(GO:0042147) |
| 0.1 | 2.2 | GO:0044804 | nucleophagy(GO:0044804) |
| 0.1 | 1.1 | GO:0061469 | regulation of type B pancreatic cell proliferation(GO:0061469) |
| 0.1 | 5.9 | GO:0032781 | positive regulation of ATPase activity(GO:0032781) |
| 0.1 | 1.2 | GO:0006750 | glutathione biosynthetic process(GO:0006750) |
| 0.1 | 15.4 | GO:0007160 | cell-matrix adhesion(GO:0007160) |
| 0.1 | 0.1 | GO:0008065 | establishment of blood-nerve barrier(GO:0008065) |
| 0.0 | 0.1 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 0.0 | 1.0 | GO:0010738 | regulation of protein kinase A signaling(GO:0010738) |
| 0.0 | 0.5 | GO:1903286 | regulation of potassium ion import(GO:1903286) |
| 0.0 | 1.9 | GO:0070527 | platelet aggregation(GO:0070527) |
| 0.0 | 2.6 | GO:2001237 | negative regulation of extrinsic apoptotic signaling pathway(GO:2001237) |
| 0.0 | 0.3 | GO:0010226 | response to lithium ion(GO:0010226) |
| 0.0 | 0.0 | GO:0048769 | sarcomerogenesis(GO:0048769) |
| 0.0 | 0.4 | GO:0006884 | cell volume homeostasis(GO:0006884) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 18.8 | 112.8 | GO:0042721 | mitochondrial inner membrane protein insertion complex(GO:0042721) |
| 12.1 | 72.4 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
| 11.6 | 115.5 | GO:0070552 | BRISC complex(GO:0070552) |
| 10.8 | 96.9 | GO:0046696 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) lipopolysaccharide receptor complex(GO:0046696) |
| 9.4 | 37.5 | GO:0005960 | glycine cleavage complex(GO:0005960) |
| 7.4 | 22.3 | GO:0005606 | laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260) |
| 6.8 | 20.4 | GO:1990913 | sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917) |
| 6.2 | 49.9 | GO:1905202 | 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202) |
| 6.2 | 24.6 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 6.0 | 48.1 | GO:0016012 | sarcoglycan complex(GO:0016012) |
| 5.7 | 45.4 | GO:0098575 | lumenal side of lysosomal membrane(GO:0098575) |
| 4.4 | 70.1 | GO:0034709 | methylosome(GO:0034709) |
| 4.3 | 21.3 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
| 4.2 | 33.9 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 3.9 | 15.8 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
| 3.4 | 98.8 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 3.4 | 13.6 | GO:0020003 | symbiont-containing vacuole(GO:0020003) |
| 3.2 | 25.8 | GO:0070761 | pre-snoRNP complex(GO:0070761) |
| 3.1 | 9.3 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
| 2.4 | 7.2 | GO:0070939 | Dsl1p complex(GO:0070939) |
| 2.4 | 87.5 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 2.4 | 11.8 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 2.3 | 15.9 | GO:0090661 | box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661) |
| 2.3 | 90.7 | GO:0005762 | organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762) |
| 2.2 | 15.2 | GO:1990111 | spermatoproteasome complex(GO:1990111) |
| 2.1 | 22.8 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 2.1 | 67.8 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 2.0 | 30.0 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 2.0 | 6.0 | GO:1990723 | cytoplasmic periphery of the nuclear pore complex(GO:1990723) |
| 1.7 | 17.1 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 1.7 | 18.8 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 1.6 | 36.3 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 1.5 | 13.4 | GO:0072546 | ER membrane protein complex(GO:0072546) |
| 1.5 | 5.8 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 1.5 | 13.1 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) |
| 1.4 | 13.0 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
| 1.4 | 26.0 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 1.4 | 17.7 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
| 1.3 | 18.6 | GO:0005686 | U2 snRNP(GO:0005686) |
| 1.3 | 9.2 | GO:0034719 | SMN-Sm protein complex(GO:0034719) |
| 1.3 | 89.5 | GO:0005637 | nuclear inner membrane(GO:0005637) |
| 1.1 | 12.1 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
| 1.1 | 50.8 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 1.0 | 14.6 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 1.0 | 7.2 | GO:1990726 | Lsm1-7-Pat1 complex(GO:1990726) |
| 1.0 | 5.1 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
| 1.0 | 17.6 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 1.0 | 43.9 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.9 | 28.6 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.8 | 2.4 | GO:0071821 | FANCM-MHF complex(GO:0071821) |
| 0.8 | 21.6 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.8 | 3.1 | GO:0005863 | striated muscle myosin thick filament(GO:0005863) |
| 0.8 | 10.9 | GO:0031088 | platelet dense granule membrane(GO:0031088) |
| 0.8 | 71.4 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.7 | 201.4 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.7 | 21.6 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.7 | 7.9 | GO:0030126 | COPI vesicle coat(GO:0030126) |
| 0.6 | 1.9 | GO:0000805 | X chromosome(GO:0000805) |
| 0.5 | 6.6 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.5 | 52.7 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.5 | 61.5 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.5 | 6.2 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.5 | 6.0 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.5 | 20.2 | GO:0031430 | M band(GO:0031430) |
| 0.5 | 6.7 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.5 | 6.1 | GO:0005915 | zonula adherens(GO:0005915) |
| 0.5 | 5.0 | GO:0042587 | glycogen granule(GO:0042587) |
| 0.4 | 2.2 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
| 0.4 | 35.2 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.4 | 2.3 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.4 | 34.9 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.3 | 3.1 | GO:0000439 | core TFIIH complex(GO:0000439) |
| 0.3 | 2.3 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
| 0.3 | 66.6 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.3 | 1.5 | GO:0030686 | 90S preribosome(GO:0030686) |
| 0.3 | 37.0 | GO:0005840 | ribosome(GO:0005840) |
| 0.3 | 39.5 | GO:0048770 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.3 | 14.9 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
| 0.3 | 37.6 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.3 | 15.6 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.3 | 26.9 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.3 | 58.3 | GO:0005802 | trans-Golgi network(GO:0005802) |
| 0.2 | 109.4 | GO:0005874 | microtubule(GO:0005874) |
| 0.2 | 2.3 | GO:0000153 | cytoplasmic ubiquitin ligase complex(GO:0000153) |
| 0.2 | 41.2 | GO:0031968 | organelle outer membrane(GO:0031968) |
| 0.2 | 6.5 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.2 | 16.7 | GO:0005811 | lipid particle(GO:0005811) |
| 0.2 | 15.6 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.2 | 3.8 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.2 | 4.7 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.2 | 9.4 | GO:0031907 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.2 | 16.0 | GO:0030175 | filopodium(GO:0030175) |
| 0.2 | 9.0 | GO:0005657 | replication fork(GO:0005657) |
| 0.2 | 4.4 | GO:0005921 | gap junction(GO:0005921) |
| 0.2 | 96.3 | GO:0048471 | perinuclear region of cytoplasm(GO:0048471) |
| 0.1 | 49.2 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.1 | 94.7 | GO:0005730 | nucleolus(GO:0005730) |
| 0.0 | 4.4 | GO:0000932 | cytoplasmic mRNA processing body(GO:0000932) |
| 0.0 | 6.2 | GO:0042383 | sarcolemma(GO:0042383) |
| 0.0 | 0.7 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
| 0.0 | 1.6 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.0 | 0.1 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.0 | 2.2 | GO:0036064 | ciliary basal body(GO:0036064) |
| 0.0 | 1.1 | GO:0035097 | histone methyltransferase complex(GO:0035097) |
| 0.0 | 0.1 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
| 0.0 | 1.2 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.0 | 35.2 | GO:0070062 | extracellular exosome(GO:0070062) |
| 0.0 | 1.8 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 20.1 | 60.2 | GO:0004639 | phosphoribosylaminoimidazole carboxylase activity(GO:0004638) phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639) |
| 19.3 | 115.5 | GO:0004793 | glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732) |
| 16.1 | 96.9 | GO:0034186 | apolipoprotein A-I binding(GO:0034186) |
| 14.4 | 100.8 | GO:0004459 | lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459) |
| 12.5 | 37.5 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
| 11.5 | 34.5 | GO:0008988 | rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) |
| 11.3 | 33.9 | GO:0004597 | peptide-aspartate beta-dioxygenase activity(GO:0004597) |
| 11.1 | 66.4 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 10.5 | 52.5 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 8.7 | 26.0 | GO:0004766 | spermidine synthase activity(GO:0004766) |
| 8.3 | 49.9 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 7.5 | 30.0 | GO:0042134 | rRNA primary transcript binding(GO:0042134) |
| 6.8 | 20.4 | GO:0002135 | CTP binding(GO:0002135) |
| 6.2 | 49.9 | GO:0004485 | methylcrotonoyl-CoA carboxylase activity(GO:0004485) |
| 6.2 | 18.7 | GO:0003978 | UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978) |
| 6.0 | 60.3 | GO:0004844 | uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506) |
| 5.8 | 29.2 | GO:0070180 | large ribosomal subunit rRNA binding(GO:0070180) |
| 5.8 | 46.3 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 5.8 | 63.4 | GO:0004673 | protein histidine kinase activity(GO:0004673) |
| 5.2 | 15.6 | GO:0044714 | GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693) |
| 5.1 | 15.4 | GO:0000035 | acyl binding(GO:0000035) |
| 5.0 | 45.4 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 4.8 | 14.4 | GO:0070362 | mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364) |
| 4.6 | 13.8 | GO:0000033 | alpha-1,3-mannosyltransferase activity(GO:0000033) |
| 4.3 | 21.5 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 4.3 | 29.9 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
| 4.2 | 33.5 | GO:0102337 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 3.9 | 27.6 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 3.5 | 24.6 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 3.2 | 12.9 | GO:0051748 | UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748) |
| 3.2 | 19.2 | GO:0004310 | farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996) |
| 3.1 | 15.5 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 3.0 | 12.1 | GO:0003976 | UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976) |
| 2.8 | 8.5 | GO:0033858 | N-acetylgalactosamine kinase activity(GO:0033858) |
| 2.8 | 38.8 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 2.7 | 13.7 | GO:0033857 | diphosphoinositol-pentakisphosphate kinase activity(GO:0033857) |
| 2.7 | 10.9 | GO:0016404 | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404) |
| 2.6 | 15.8 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 2.5 | 5.0 | GO:0031177 | phosphopantetheine binding(GO:0031177) |
| 2.4 | 130.1 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 2.3 | 18.6 | GO:0030620 | U2 snRNA binding(GO:0030620) |
| 2.3 | 13.8 | GO:0005353 | fructose transmembrane transporter activity(GO:0005353) |
| 2.3 | 15.9 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 2.2 | 24.6 | GO:0046790 | virion binding(GO:0046790) |
| 2.2 | 102.8 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) |
| 2.2 | 13.1 | GO:0005047 | signal recognition particle binding(GO:0005047) |
| 2.1 | 72.2 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 2.0 | 30.2 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 2.0 | 18.0 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 1.9 | 13.0 | GO:0051425 | PTB domain binding(GO:0051425) |
| 1.8 | 5.5 | GO:0004730 | pseudouridylate synthase activity(GO:0004730) |
| 1.8 | 11.0 | GO:0022833 | mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833) |
| 1.7 | 6.9 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 1.7 | 5.1 | GO:0004346 | glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309) |
| 1.6 | 80.8 | GO:0004864 | protein phosphatase inhibitor activity(GO:0004864) |
| 1.6 | 32.1 | GO:0005337 | nucleoside transmembrane transporter activity(GO:0005337) |
| 1.6 | 16.0 | GO:0034485 | phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) |
| 1.6 | 7.9 | GO:0004530 | deoxyribonuclease I activity(GO:0004530) |
| 1.6 | 7.8 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
| 1.6 | 53.2 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
| 1.5 | 29.1 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 1.4 | 158.0 | GO:0008565 | protein transporter activity(GO:0008565) |
| 1.4 | 73.3 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 1.3 | 20.0 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
| 1.3 | 4.0 | GO:0015218 | pyrimidine nucleotide transmembrane transporter activity(GO:0015218) |
| 1.2 | 19.0 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 1.1 | 5.7 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
| 1.1 | 22.8 | GO:0000339 | RNA cap binding(GO:0000339) |
| 1.1 | 33.5 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 1.1 | 9.6 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 1.0 | 18.8 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 1.0 | 30.3 | GO:0008266 | poly(U) RNA binding(GO:0008266) |
| 1.0 | 9.3 | GO:0000990 | transcription factor activity, core RNA polymerase binding(GO:0000990) |
| 1.0 | 25.7 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 1.0 | 20.6 | GO:0015037 | peptide disulfide oxidoreductase activity(GO:0015037) |
| 1.0 | 5.8 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.9 | 5.5 | GO:0031694 | alpha-2A adrenergic receptor binding(GO:0031694) |
| 0.9 | 6.4 | GO:0004169 | dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169) |
| 0.9 | 4.4 | GO:0019776 | Atg8 ligase activity(GO:0019776) |
| 0.9 | 12.4 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.9 | 26.3 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.9 | 48.5 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.8 | 12.6 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.8 | 17.7 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.8 | 13.2 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.8 | 42.9 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.7 | 14.1 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.7 | 6.1 | GO:0047623 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.7 | 12.1 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.7 | 3.3 | GO:0004084 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.7 | 9.4 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.7 | 137.7 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.6 | 7.0 | GO:0035381 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.6 | 17.1 | GO:0005527 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.6 | 11.8 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.6 | 8.0 | GO:0016634 | oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634) |
| 0.6 | 10.8 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.6 | 27.3 | GO:0004407 | histone deacetylase activity(GO:0004407) |
| 0.6 | 9.3 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.6 | 1.7 | GO:0070259 | tyrosyl-DNA phosphodiesterase activity(GO:0070259) |
| 0.5 | 15.2 | GO:0070003 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.5 | 4.2 | GO:1990239 | steroid hormone binding(GO:1990239) |
| 0.5 | 3.1 | GO:0018479 | benzaldehyde dehydrogenase (NAD+) activity(GO:0018479) |
| 0.5 | 43.1 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.5 | 5.0 | GO:0047760 | butyrate-CoA ligase activity(GO:0047760) |
| 0.4 | 23.9 | GO:0030145 | manganese ion binding(GO:0030145) |
| 0.4 | 16.7 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.4 | 3.7 | GO:0016274 | arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274) |
| 0.4 | 5.7 | GO:0031419 | cobalamin binding(GO:0031419) |
| 0.4 | 11.2 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.4 | 12.7 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.4 | 6.1 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.3 | 2.0 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) |
| 0.3 | 100.2 | GO:0015631 | tubulin binding(GO:0015631) |
| 0.3 | 5.1 | GO:0030515 | snoRNA binding(GO:0030515) |
| 0.3 | 8.1 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.3 | 135.2 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.3 | 20.2 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.3 | 9.4 | GO:0015301 | anion:anion antiporter activity(GO:0015301) |
| 0.3 | 30.5 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.3 | 5.9 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.3 | 3.1 | GO:0097493 | structural molecule activity conferring elasticity(GO:0097493) |
| 0.2 | 2.9 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 0.2 | 0.9 | GO:0099580 | ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580) |
| 0.2 | 22.3 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.2 | 8.1 | GO:0051539 | 4 iron, 4 sulfur cluster binding(GO:0051539) |
| 0.2 | 1.5 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.2 | 5.2 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.2 | 6.1 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.2 | 6.2 | GO:0016504 | peptidase activator activity(GO:0016504) |
| 0.2 | 8.3 | GO:0016811 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811) |
| 0.1 | 1.0 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022) |
| 0.1 | 1.1 | GO:0000403 | Y-form DNA binding(GO:0000403) |
| 0.1 | 4.8 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.1 | 2.5 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
| 0.1 | 7.8 | GO:0016776 | phosphotransferase activity, phosphate group as acceptor(GO:0016776) |
| 0.1 | 11.5 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.1 | 1.9 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.1 | 1.1 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.1 | 1.8 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
| 0.1 | 3.1 | GO:0031593 | polyubiquitin binding(GO:0031593) |
| 0.1 | 0.8 | GO:0016813 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813) |
| 0.1 | 2.2 | GO:0003678 | DNA helicase activity(GO:0003678) |
| 0.1 | 1.0 | GO:0034237 | protein kinase A regulatory subunit binding(GO:0034237) |
| 0.0 | 0.7 | GO:0070034 | telomerase RNA binding(GO:0070034) |
| 0.0 | 0.7 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 0.0 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 0.0 | 0.3 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
| 0.0 | 0.3 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 0.0 | 0.4 | GO:0015379 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 0.0 | 1.2 | GO:0004180 | carboxypeptidase activity(GO:0004180) |
| 0.0 | 3.7 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 0.1 | GO:0043295 | glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
| 0.0 | 3.0 | GO:0005516 | calmodulin binding(GO:0005516) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 7.8 | 155.1 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 3.8 | 72.2 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 3.1 | 436.2 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 1.2 | 22.3 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.9 | 47.3 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.8 | 49.6 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 0.7 | 58.2 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.6 | 20.2 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.5 | 52.5 | PID HDAC CLASSI PATHWAY | Signaling events mediated by HDAC Class I |
| 0.5 | 7.0 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.4 | 24.6 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.4 | 18.8 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.3 | 25.5 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.3 | 38.5 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.3 | 18.5 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.3 | 62.3 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.3 | 22.8 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.3 | 25.5 | WNT SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.3 | 16.5 | PID E2F PATHWAY | E2F transcription factor network |
| 0.3 | 9.0 | PID NCADHERIN PATHWAY | N-cadherin signaling events |
| 0.2 | 9.6 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.2 | 7.8 | PID IFNG PATHWAY | IFN-gamma pathway |
| 0.2 | 10.7 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.2 | 12.7 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.2 | 13.2 | PID ERA GENOMIC PATHWAY | Validated nuclear estrogen receptor alpha network |
| 0.2 | 6.1 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.2 | 9.0 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.1 | 6.9 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 3.5 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.1 | 5.0 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.1 | 2.1 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.1 | 1.5 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.1 | 4.5 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.1 | 1.7 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 11.3 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.0 | 0.5 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.0 | 0.5 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 8.8 | 177.0 | REACTOME METABOLISM OF POLYAMINES | Genes involved in Metabolism of polyamines |
| 6.9 | 103.5 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 4.5 | 49.5 | REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION | Genes involved in APOBEC3G mediated resistance to HIV-1 infection |
| 3.8 | 98.8 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 3.5 | 204.4 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 2.6 | 85.3 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 2.1 | 21.3 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 2.0 | 72.4 | REACTOME MEIOTIC RECOMBINATION | Genes involved in Meiotic Recombination |
| 2.0 | 33.4 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 1.8 | 24.6 | REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA | Genes involved in Activation of Chaperone Genes by ATF6-alpha |
| 1.7 | 15.5 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 1.7 | 68.4 | REACTOME FATTY ACYL COA BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
| 1.6 | 29.1 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 1.6 | 52.7 | REACTOME PYRUVATE METABOLISM | Genes involved in Pyruvate metabolism |
| 1.3 | 36.2 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 1.2 | 27.6 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 1.1 | 22.5 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 1.1 | 26.9 | REACTOME PURINE SALVAGE | Genes involved in Purine salvage |
| 1.0 | 45.4 | REACTOME LYSOSOME VESICLE BIOGENESIS | Genes involved in Lysosome Vesicle Biogenesis |
| 1.0 | 43.1 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 1.0 | 17.7 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.9 | 7.9 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.9 | 25.9 | REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN | Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein |
| 0.9 | 74.5 | REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S | Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S |
| 0.8 | 43.1 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.8 | 17.3 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.7 | 32.7 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.7 | 9.3 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.7 | 10.6 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.7 | 26.9 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.6 | 62.5 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.5 | 15.3 | REACTOME FORMATION OF INCISION COMPLEX IN GG NER | Genes involved in Formation of incision complex in GG-NER |
| 0.5 | 12.9 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.5 | 28.1 | REACTOME TRANSLATION | Genes involved in Translation |
| 0.5 | 12.7 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.5 | 16.5 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.5 | 11.9 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.5 | 21.9 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.4 | 33.5 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.4 | 13.3 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 0.4 | 2.3 | REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND | Genes involved in Processive synthesis on the lagging strand |
| 0.4 | 23.1 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.4 | 7.2 | REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
| 0.4 | 4.4 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.3 | 13.5 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.3 | 9.4 | REACTOME PEROXISOMAL LIPID METABOLISM | Genes involved in Peroxisomal lipid metabolism |
| 0.3 | 18.0 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.3 | 6.9 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.3 | 6.6 | REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
| 0.3 | 33.0 | REACTOME HOST INTERACTIONS OF HIV FACTORS | Genes involved in Host Interactions of HIV factors |
| 0.3 | 8.0 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.3 | 4.4 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.2 | 17.8 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.2 | 17.7 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.2 | 5.6 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.1 | 6.7 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.1 | 2.1 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.1 | 1.9 | REACTOME SIGNALING BY SCF KIT | Genes involved in Signaling by SCF-KIT |
| 0.1 | 6.1 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.1 | 1.7 | REACTOME DOUBLE STRAND BREAK REPAIR | Genes involved in Double-Strand Break Repair |
| 0.1 | 0.9 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.1 | 2.1 | REACTOME TRIGLYCERIDE BIOSYNTHESIS | Genes involved in Triglyceride Biosynthesis |
| 0.1 | 4.2 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 0.1 | 2.9 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.1 | 3.1 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.1 | 4.0 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 2.2 | REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING | Genes involved in Negative regulators of RIG-I/MDA5 signaling |
| 0.0 | 1.1 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.0 | 0.7 | REACTOME EXTENSION OF TELOMERES | Genes involved in Extension of Telomeres |
| 0.0 | 5.0 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.0 | 4.3 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 1.5 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.0 | 8.5 | REACTOME METABOLISM OF CARBOHYDRATES | Genes involved in Metabolism of carbohydrates |
| 0.0 | 3.2 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 0.9 | REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION | Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription |
| 0.0 | 2.3 | REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING | Genes involved in p75 NTR receptor-mediated signalling |
| 0.0 | 0.5 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.0 | 0.3 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |