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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for CREB1

Z-value: 13.43

Motif logo

Transcription factors associated with CREB1

Gene Symbol Gene ID Gene Info
ENSG00000118260.15 CREB1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CREB1hg38_v1_chr2_+_207529731_2075297470.632.2e-25Click!

Activity profile of CREB1 motif

Sorted Z-values of CREB1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_-_17246846 120.13 ENST00000628418.1
ENST00000361272.9
ENST00000523917.5
CCR4-NOT transcription complex subunit 7
chr6_-_17706748 90.07 ENST00000613258.4
ENST00000537253.5
nucleoporin 153
chr6_-_17706852 89.83 ENST00000262077.3
nucleoporin 153
chr3_+_44976236 67.26 ENST00000265564.8
exosome component 7
chr2_-_68062974 46.34 ENST00000407324.5
ENST00000355848.7
ENST00000410067.8
ENST00000409302.1
C1D nuclear receptor corepressor
chr1_-_53238485 45.55 ENST00000371466.4
ENST00000371470.8
mago homolog, exon junction complex subunit
chr15_-_34101807 40.38 ENST00000527822.5
ENST00000528949.1
ENST00000256545.9
ER membrane protein complex subunit 7
chr22_+_20117734 38.90 ENST00000416427.5
ENST00000421656.5
ENST00000423859.5
ENST00000418705.2
RAN binding protein 1
chr6_-_31958431 38.49 ENST00000625905.1
ENST00000454913.5
ENST00000436289.6
negative elongation factor complex member E
chr6_-_43059367 38.36 ENST00000230413.9
ENST00000487429.1
ENST00000388752.8
ENST00000489623.1
ENST00000468957.1
mitochondrial ribosomal protein L2
chr4_+_145098269 37.83 ENST00000502586.5
ENST00000296577.9
ATP binding cassette subfamily E member 1
chr17_-_49708145 36.44 ENST00000514907.5
ENST00000503334.5
ENST00000508520.5
solute carrier family 35 member B1
chr14_-_60981034 35.88 ENST00000555420.1
ENST00000261249.7
ENST00000553903.1
tRNA methyltransferase 5
chr11_-_126268810 35.62 ENST00000332118.11
SRP receptor subunit alpha
chr3_-_53255990 35.54 ENST00000423525.6
transketolase
chr14_+_104753120 34.29 ENST00000535554.4
ENST00000329967.11
ENST00000347067.9
ENST00000553810.5
SIVA1 apoptosis inducing factor
chr12_+_132144417 33.98 ENST00000330579.6
nucleolar complex associated 4 homolog
chr11_-_62839564 32.73 ENST00000311713.11
ENST00000278856.9
WD repeat domain 74
chr6_-_31958852 32.57 ENST00000375425.9
ENST00000426722.5
negative elongation factor complex member E
chr6_-_31806937 31.78 ENST00000375661.6
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr2_+_113437691 31.60 ENST00000259199.9
ENST00000416503.6
ENST00000433343.6
COBW domain containing 2
chr6_-_31958935 31.41 ENST00000441998.5
ENST00000444811.6
ENST00000375429.8
negative elongation factor complex member E
chr11_+_60842095 29.74 ENST00000227520.10
coiled-coil domain containing 86
chr3_-_196942377 29.65 ENST00000447325.5
nuclear cap binding protein subunit 2
chr21_-_43107553 29.47 ENST00000380276.6
ENST00000291552.9
U2 small nuclear RNA auxiliary factor 1
chr7_+_23105747 29.21 ENST00000322275.9
ENST00000339077.10
kelch like family member 7
chr3_-_196942427 28.76 ENST00000411704.1
ENST00000452404.6
nuclear cap binding protein subunit 2
chr12_-_123633604 28.71 ENST00000534960.5
ENST00000424014.7
eukaryotic translation initiation factor 2B subunit alpha
chr12_+_69239592 28.62 ENST00000456847.7
ENST00000266679.8
cleavage and polyadenylation specific factor 6
chr19_+_10251901 28.44 ENST00000592514.5
ENST00000307422.9
ENST00000590150.5
ENST00000590669.5
mitochondrial ribosomal protein L4
chr2_-_28870266 28.34 ENST00000306108.10
tRNA methyltransferase 61B
chr1_+_145607978 28.08 ENST00000313835.14
ENST00000534502.5
G protein-coupled receptor 89A
chr13_+_102596972 27.96 ENST00000376052.5
ENST00000376065.8
ENST00000652308.1
ENST00000651544.1
tripeptidyl peptidase 2
chr21_-_6499202 27.84 ENST00000619610.2
ENST00000610664.5
ENST00000639996.1
U2 small nuclear RNA auxiliary factor 1 like 5
chr1_-_229508287 27.68 ENST00000261396.6
nucleoporin 133
chr14_+_23306958 27.54 ENST00000554635.1
ENST00000557008.2
BCL2 like 2
BCL2L2-PABPN1 readthrough
chr9_-_32573150 27.48 ENST00000379847.8
ENST00000350021.2
NADH:ubiquinone oxidoreductase subunit B6
chr22_+_20117497 27.12 ENST00000331821.7
ENST00000411892.5
RAN binding protein 1
chr15_+_80059635 27.01 ENST00000559157.5
zinc finger AN1-type containing 6
chr9_-_41189310 26.53 ENST00000456520.5
ENST00000377391.8
ENST00000613716.4
ENST00000617933.1
COBW domain containing 6
chr1_-_186375325 26.33 ENST00000613151.1
translocated promoter region, nuclear basket protein
chr12_-_120446372 26.29 ENST00000546954.2
TP53 regulated inhibitor of apoptosis 1
chr17_+_8249273 26.17 ENST00000584044.5
ENST00000314666.11
ENST00000581242.3
phosphoribosylformylglycinamidine synthase
chr2_-_240025380 25.92 ENST00000676782.1
ENST00000677407.1
ENST00000678914.1
ENST00000677294.1
ENST00000676491.1
ENST00000677567.1
ENST00000679158.1
ENST00000448880.6
ENST00000677263.1
ENST00000678289.1
ENST00000678737.1
NADH:ubiquinone oxidoreductase subunit A10
chr9_+_68241854 25.86 ENST00000616550.4
ENST00000618217.4
ENST00000377342.9
ENST00000478048.5
ENST00000360171.11
COBW domain containing 3
chr12_+_107685759 25.56 ENST00000412830.8
ENST00000547995.5
PWP1 homolog, endonuclein
chr9_+_65675834 25.53 ENST00000377392.9
ENST00000377384.5
ENST00000430059.6
ENST00000429800.6
ENST00000382405.8
ENST00000377395.8
COBW domain containing 5
chrX_+_24054931 25.10 ENST00000253039.9
ENST00000423068.1
eukaryotic translation initiation factor 2 subunit gamma
chr1_-_114716729 24.99 ENST00000369535.5
NRAS proto-oncogene, GTPase
chr9_-_179008 24.99 ENST00000613508.4
ENST00000382447.8
ENST00000382389.5
ENST00000377447.7
ENST00000382393.2
ENST00000314367.14
ENST00000356521.8
ENST00000377400.8
COBW domain containing 1
chr15_+_80059568 24.99 ENST00000613266.4
ENST00000561060.5
zinc finger AN1-type containing 6
chrX_-_47659128 24.55 ENST00000333119.7
ENST00000335890.3
ubiquitously expressed prefoldin like chaperone
chr17_-_782317 23.88 ENST00000301329.10
glyoxalase domain containing 4
chr2_-_240025299 23.83 ENST00000404554.5
ENST00000407129.3
ENST00000307300.8
ENST00000678455.1
ENST00000444548.6
ENST00000252711.7
ENST00000620965.5
ENST00000443626.5
NADH:ubiquinone oxidoreductase subunit A10
chr17_-_49707900 23.78 ENST00000511763.6
ENST00000515850.6
ENST00000649906.1
ENST00000240333.12
solute carrier family 35 member B1
chr17_-_782253 23.58 ENST00000628529.2
ENST00000625892.1
ENST00000301328.9
ENST00000576419.1
glyoxalase domain containing 4
chr9_-_32573173 23.37 ENST00000366466.5
NADH:ubiquinone oxidoreductase subunit B6
chr3_+_141738263 23.36 ENST00000480908.1
ENST00000393000.3
ENST00000273480.4
ring finger protein 7
chr2_-_3558280 23.20 ENST00000315212.4
ribonuclease H1
chr11_+_34105582 22.88 ENST00000531159.6
ENST00000257829.8
N-acetyltransferase 10
chr17_+_75667315 22.36 ENST00000584667.6
ENST00000355423.7
SAP30 binding protein
chr12_+_69239627 22.24 ENST00000551516.1
cleavage and polyadenylation specific factor 6
chr3_-_53256009 21.96 ENST00000296289.10
ENST00000462138.6
ENST00000423516.5
transketolase
chr19_+_10252206 21.48 ENST00000253099.11
ENST00000393733.6
ENST00000588502.5
mitochondrial ribosomal protein L4
chr3_-_9986682 21.04 ENST00000429759.5
ER membrane protein complex subunit 3
chrX_-_154019800 20.88 ENST00000444230.5
ENST00000393687.6
ENST00000429936.6
ENST00000369974.6
ENST00000369980.8
interleukin 1 receptor associated kinase 1
chr1_-_35641498 20.64 ENST00000373237.4
proteasome 20S subunit beta 2
chr6_-_144095556 20.52 ENST00000367569.4
splicing factor 3b subunit 5
chr1_+_186375813 20.42 ENST00000419367.8
ENST00000287859.11
ENST00000367470.8
odr-4 GPCR localization factor homolog
chr19_+_54115726 20.30 ENST00000445811.5
ENST00000321030.9
ENST00000445124.5
ENST00000447810.5
pre-mRNA processing factor 31
chr17_+_35587478 20.09 ENST00000618940.4
adaptor related protein complex 2 subunit beta 1
chr12_-_45990519 19.83 ENST00000266589.10
ENST00000369367.8
ENST00000395453.2
ENST00000395454.6
SR-related CTD associated factor 11
chr2_-_130181542 19.83 ENST00000441135.1
ENST00000680679.1
ENST00000680401.1
ENST00000351288.10
ENST00000680298.1
ENST00000431183.6
sphingomyelin phosphodiesterase 4
chr9_-_33001522 19.66 ENST00000463596.6
ENST00000673598.1
ENST00000477119.2
ENST00000673416.1
ENST00000309615.8
ENST00000397172.8
ENST00000379813.7
ENST00000379819.6
ENST00000379825.7
ENST00000379817.7
ENST00000672438.1
ENST00000476858.6
aprataxin
chr14_-_54441325 19.62 ENST00000556113.1
ENST00000553660.5
ENST00000216416.9
ENST00000395573.8
ENST00000557690.5
cornichon family AMPA receptor auxiliary protein 1
chr1_-_220046432 19.58 ENST00000609181.5
ENST00000366923.8
glutamyl-prolyl-tRNA synthetase 1
chr17_+_75667390 18.86 ENST00000583536.5
SAP30 binding protein
chr17_-_48944772 18.83 ENST00000290330.7
ENST00000502492.6
SNF8 subunit of ESCRT-II
chr4_+_112637120 18.26 ENST00000509061.5
ENST00000344442.10
ENST00000508577.5
ENST00000513553.5
La ribonucleoprotein 7, transcriptional regulator
chr5_-_133968578 18.05 ENST00000231512.5
chromosome 5 open reading frame 15
chr6_+_41787651 17.77 ENST00000398884.7
ENST00000398881.4
translocase of outer mitochondrial membrane 6
chr3_-_101686690 17.63 ENST00000469605.1
ENST00000495401.5
ENST00000394077.8
ribosomal protein L24
chr16_+_19067893 17.62 ENST00000544894.6
ENST00000561858.5
coenzyme Q7, hydroxylase
chr1_-_31644866 17.49 ENST00000373703.5
penta-EF-hand domain containing 1
chr11_-_66345066 17.08 ENST00000359957.8
ENST00000425825.6
BRMS1 transcriptional repressor and anoikis regulator
chr2_+_130181662 17.05 ENST00000425361.5
ENST00000457492.5
mitotic spindle organizing protein 2B
chr3_-_44976117 17.04 ENST00000342790.8
ENST00000424952.7
ENST00000339420.7
ENST00000296127.7
ENST00000455235.5
zinc finger DHHC-type palmitoyltransferase 3
chr17_+_59565598 16.99 ENST00000251241.9
ENST00000425628.7
ENST00000584385.5
ENST00000580030.1
DEAH-box helicase 40
chr16_-_3717505 16.80 ENST00000538171.5
ENST00000246957.10
TNF receptor associated protein 1
chr20_+_56468585 16.75 ENST00000023939.8
ENST00000395881.7
ENST00000357348.10
ENST00000449062.1
replication termination factor 2
chr1_+_147928420 16.70 ENST00000314163.12
ENST00000468618.6
G protein-coupled receptor 89B
chr15_+_80059651 16.51 ENST00000561012.5
ENST00000261749.11
ENST00000564367.5
ENST00000558494.5
zinc finger AN1-type containing 6
chr3_-_196942500 16.41 ENST00000321256.10
ENST00000427641.2
nuclear cap binding protein subunit 2
chr8_+_100150621 16.29 ENST00000522439.1
ENST00000353107.8
RNA polymerase II, I and III subunit K
chr7_+_23181994 16.25 ENST00000410002.7
ENST00000258742.10
ENST00000413919.1
nucleoporin 42
chr9_-_92115383 16.09 ENST00000337841.4
ENST00000262554.7
serine palmitoyltransferase long chain base subunit 1
chr17_-_38825303 16.01 ENST00000614790.5
CWC25 spliceosome associated protein homolog
chr5_-_179806830 15.85 ENST00000292591.12
alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B
chr6_-_34888004 15.84 ENST00000650109.1
ENST00000361288.9
ENST00000420584.3
TATA-box binding protein associated factor 11
chr8_-_125091727 15.77 ENST00000517845.5
ENST00000318410.12
WASH complex subunit 5
chr3_-_52409783 15.71 ENST00000470173.1
ENST00000296288.9
ENST00000460680.6
BRCA1 associated protein 1
chr9_-_132079856 15.70 ENST00000651555.1
ENST00000651950.1
ENST00000357028.6
ENST00000474263.1
ENST00000292035.10
mediator complex subunit 27
chr17_+_782340 15.61 ENST00000304478.9
mitochondrial rRNA methyltransferase 3
chr4_-_39366342 15.42 ENST00000503784.1
ENST00000349703.7
ENST00000381897.5
replication factor C subunit 1
chr1_-_154627945 14.99 ENST00000681683.1
ENST00000368471.8
ENST00000649042.1
ENST00000680270.1
ENST00000649022.2
ENST00000681056.1
ENST00000649724.1
adenosine deaminase RNA specific
chr9_+_137188646 14.93 ENST00000322310.10
SS nuclear autoantigen 1
chr4_+_121801311 14.70 ENST00000379663.7
ENST00000243498.10
ENST00000509800.5
exosome component 9
chr6_+_37433197 14.57 ENST00000455891.5
ENST00000373451.9
cap methyltransferase 1
chr1_-_154627576 14.50 ENST00000648311.1
adenosine deaminase RNA specific
chr17_+_42833390 14.23 ENST00000590720.6
ENST00000586114.5
ENST00000585805.5
ENST00000441946.6
ENST00000591152.5
ENST00000589469.5
ENST00000293362.7
ENST00000592169.2
proteasome activator subunit 3
chr16_-_20741792 14.12 ENST00000396083.7
THUMP domain containing 1
chr7_-_94004345 14.11 ENST00000222547.8
ENST00000433727.5
Bet1 golgi vesicular membrane trafficking protein
chr19_+_10871516 13.58 ENST00000327064.9
ENST00000588947.5
coactivator associated arginine methyltransferase 1
chr19_-_5719849 13.57 ENST00000590729.5
lon peptidase 1, mitochondrial
chr9_+_137188697 13.47 ENST00000464553.2
SS nuclear autoantigen 1
chr17_+_35587239 12.86 ENST00000621914.4
ENST00000621668.4
ENST00000616681.4
ENST00000612035.4
ENST00000610402.5
ENST00000614600.4
ENST00000590432.5
ENST00000612116.5
adaptor related protein complex 2 subunit beta 1
chr1_+_44775531 12.85 ENST00000396651.8
ENST00000372209.3
ribosomal protein S8
chr11_+_65122301 12.73 ENST00000534078.1
ENST00000526171.5
ENST00000279242.7
ENST00000531705.1
ENST00000533943.1
mitochondrial ribosomal protein L49
chr4_-_4542034 12.70 ENST00000306200.7
syntaxin 18
chr8_+_132775340 12.18 ENST00000622263.4
ENST00000220847.8
ENST00000395379.5
ENST00000395386.7
ENST00000485595.5
ENST00000337920.8
PHD finger protein 20 like 1
chr16_+_70346856 11.91 ENST00000302243.12
ENST00000417604.6
DEAD-box helicase 19A
chr4_-_145098183 11.89 ENST00000451299.6
ENST00000507656.6
ENST00000309439.9
anaphase promoting complex subunit 10
chr19_-_5720159 11.60 ENST00000593119.5
lon peptidase 1, mitochondrial
chr11_-_62805429 11.58 ENST00000294172.7
ENST00000531131.1
ENST00000530875.5
ENST00000531709.6
nuclear RNA export factor 1
chr19_+_35629027 11.56 ENST00000588161.5
ENST00000262633.9
ENST00000592202.5
ENST00000586618.5
ENST00000589559.5
RNA binding motif protein 42
chr16_-_2268373 11.43 ENST00000566458.5
RNA binding protein with serine rich domain 1
chr19_-_18919348 11.43 ENST00000349893.8
ENST00000351079.8
ENST00000600932.5
ENST00000262812.9
COPI coat complex subunit epsilon
chr5_-_75511213 11.31 ENST00000644445.1
ENST00000646302.1
ENST00000644912.1
ENST00000642809.1
ENST00000644377.1
ceramide transporter 1
chr2_+_95402688 11.22 ENST00000233379.9
ENST00000445649.1
ENST00000447036.5
ENST00000418606.1
fumarylacetoacetate hydrolase domain containing 2A
chr15_+_22838635 11.04 ENST00000398014.7
ENST00000359727.8
ENST00000674173.1
ENST00000337451.8
ENST00000674289.1
ENST00000674477.1
ENST00000398013.7
ENST00000674330.1
ENST00000560039.1
ENST00000539711.2
NIPA magnesium transporter 2
chr7_+_44606619 10.91 ENST00000222673.6
ENST00000444676.5
ENST00000631326.2
oxoglutarate dehydrogenase
chr6_-_106325416 10.74 ENST00000343245.7
autophagy related 5
chr19_+_35629107 10.53 ENST00000589871.1
RNA binding motif protein 42
chr14_+_30622304 9.74 ENST00000676658.1
ENST00000679165.1
ENST00000676509.1
ENST00000678716.1
ENST00000678402.1
ENST00000678124.1
ENST00000677413.1
ENST00000553693.6
ENST00000469043.2
ENST00000676954.1
ENST00000676812.1
ENST00000678669.1
ENST00000676520.1
ENST00000557076.6
ENST00000544052.6
ENST00000458591.7
ENST00000677340.1
ENST00000676674.1
ENST00000396629.6
ENST00000678579.1
sec1 family domain containing 1
chr9_+_131125578 9.67 ENST00000359428.10
ENST00000411637.6
ENST00000652454.1
nucleoporin 214
chr14_+_60981114 9.56 ENST00000354886.6
solute carrier family 38 member 6
chr6_-_106325735 9.53 ENST00000635758.2
ENST00000369076.8
ENST00000636437.1
autophagy related 5
chr9_+_111631354 9.41 ENST00000374294.3
DNAJC25-GNG10 readthrough
chr6_-_106325616 9.38 ENST00000360666.6
autophagy related 5
chr4_-_145098135 9.32 ENST00000502847.1
ENST00000513054.5
anaphase promoting complex subunit 10
chr1_-_186375239 9.10 ENST00000367478.9
translocated promoter region, nuclear basket protein
chr11_+_66843413 9.09 ENST00000524506.5
ENST00000309657.8
Ras converting CAAX endopeptidase 1
chr12_+_63780126 9.02 ENST00000537373.5
ribitol xylosyltransferase 1
chr3_+_185586270 8.95 ENST00000296257.10
SUMO specific peptidase 2
chr11_+_67428446 8.84 ENST00000524934.5
ENST00000312629.10
ENST00000420069.3
ribosomal protein S6 kinase B2
chr4_-_145098541 8.81 ENST00000613466.4
ENST00000514390.5
anaphase promoting complex subunit 10
chr16_+_1309621 8.80 ENST00000397515.6
ENST00000397514.8
ENST00000567383.6
ENST00000403747.6
ubiquitin conjugating enzyme E2 I
chr4_-_73258785 8.59 ENST00000639793.1
ENST00000358602.9
ENST00000330838.10
ENST00000561029.1
ankyrin repeat domain 17
chr9_+_93576557 8.56 ENST00000359246.9
ENST00000375376.8
PHD finger protein 2
chr11_-_65122057 8.56 ENST00000531743.5
ENST00000527548.5
ENST00000526555.5
ENST00000529639.6
ENST00000279259.7
FAU ubiquitin like and ribosomal protein S30 fusion
chr12_+_63779894 8.53 ENST00000261234.11
ribitol xylosyltransferase 1
chr16_+_19067639 8.30 ENST00000568985.5
ENST00000566110.5
coenzyme Q7, hydroxylase
chr11_+_57712574 8.30 ENST00000278422.9
ENST00000378312.8
thioredoxin related transmembrane protein 2
chr15_-_58749569 8.27 ENST00000402627.5
ENST00000559053.1
ENST00000260408.8
ENST00000561288.1
ENST00000461408.2
ENST00000439637.5
ENST00000558004.1
ADAM metallopeptidase domain 10
chr15_-_72783685 8.22 ENST00000456471.3
ENST00000311669.12
ADP dependent glucokinase
chr3_+_114056728 8.20 ENST00000485050.5
ENST00000281273.8
ENST00000479882.5
ENST00000493014.1
queuine tRNA-ribosyltransferase accessory subunit 2
chr19_-_5720131 7.86 ENST00000587365.1
ENST00000360614.8
ENST00000585374.5
lon peptidase 1, mitochondrial
chr14_+_23306816 7.66 ENST00000678311.1
ENST00000557579.2
ENST00000250405.10
ENST00000679000.1
ENST00000557236.6
ENST00000678502.1
ENST00000553781.5
BCL2 like 2
BCL2L2-PABPN1 readthrough
chr16_+_29816084 7.63 ENST00000320330.8
PAXIP1 associated glutamate rich protein 1
chr21_+_43659528 7.60 ENST00000340648.6
ribosomal RNA processing 1B
chr8_-_37899454 7.01 ENST00000522727.5
ENST00000287263.8
ENST00000330843.9
RAB11 family interacting protein 1
chr6_+_41921491 6.97 ENST00000230340.9
bystin like
chr2_+_108719473 6.92 ENST00000283195.11
RAN binding protein 2
chr22_+_26483851 6.83 ENST00000215917.11
SRR1 domain containing
chrX_+_136497586 6.81 ENST00000218364.5
HIV-1 Tat specific factor 1
chr4_-_39458900 6.81 ENST00000503040.5
ENST00000508595.6
ENST00000295955.14
ENST00000645496.2
ribosomal protein L9
chr16_+_1972035 6.66 ENST00000568546.6
ENST00000615855.4
transducin beta like 3
chr5_-_75511596 6.43 ENST00000643158.1
ENST00000261415.12
ENST00000646713.1
ENST00000643773.1
ENST00000645866.1
ENST00000644072.2
ENST00000643780.2
ENST00000645483.1
ENST00000642556.1
ENST00000646511.1
ceramide transporter 1
chr15_+_63189554 6.21 ENST00000559006.1
ENST00000321437.9
RAB8B, member RAS oncogene family
chr9_+_131125973 6.20 ENST00000651639.1
ENST00000451030.5
ENST00000531584.1
nucleoporin 214
chr16_+_1309136 6.16 ENST00000325437.9
ubiquitin conjugating enzyme E2 I
chr16_-_68023201 5.74 ENST00000332395.7
DEAD-box helicase 28
chr9_-_120793343 5.73 ENST00000684047.1
F-box and WD repeat domain containing 2
chr11_+_20387681 5.63 ENST00000437750.2
ENST00000331079.11
protein arginine methyltransferase 3
chr11_-_65122177 5.50 ENST00000434372.2
FAU ubiquitin like and ribosomal protein S30 fusion
chr4_-_39458876 5.47 ENST00000449470.6
ENST00000503277.6
ribosomal protein L9
chr17_-_81512671 5.42 ENST00000679480.1
ENST00000644774.2
ENST00000571721.6
ENST00000575842.5
ENST00000575087.5
ENST00000573283.7
ENST00000571691.6
ENST00000570382.2
actin gamma 1
chr12_-_121793668 5.31 ENST00000267205.7
ras homolog family member F, filopodia associated
chr14_+_31561376 5.18 ENST00000550649.5
ENST00000281081.12
nucleotide binding protein like
chr16_-_2268054 5.12 ENST00000561518.5
ENST00000561718.5
ENST00000567147.5
ENST00000562690.5
ENST00000569598.6
RNA binding protein with serine rich domain 1
chr12_-_57772087 5.04 ENST00000324871.12
ENST00000257848.7
methyltransferase like 1
chr20_-_62861763 4.97 ENST00000217162.5
ENST00000335351.8
transcription factor like 5
chr19_-_45730861 4.61 ENST00000317683.4
F-box protein 46
chr4_-_75514261 4.45 ENST00000380840.6
ENST00000513257.5
ENST00000507014.1
ring finger and CHY zinc finger domain containing 1
chr9_+_93576708 4.21 ENST00000610682.1
PHD finger protein 2
chr2_+_119223815 4.18 ENST00000393106.6
ENST00000393110.7
ENST00000409811.5
ENST00000393107.2
STEAP3 metalloreductase
chr8_+_37736612 4.16 ENST00000518526.5
ENST00000523887.5
ENST00000648919.1
ENST00000519638.3
ER lipid raft associated 2
chr9_-_120793377 4.12 ENST00000684001.1
ENST00000684405.1
ENST00000608872.6
F-box and WD repeat domain containing 2
chr15_-_66497708 4.05 ENST00000566658.1
ENST00000563480.6
ENST00000395589.6
ENST00000316634.6
ENST00000307979.7
small nuclear RNA activating complex polypeptide 5
chr3_+_30606574 3.90 ENST00000295754.10
ENST00000359013.4
transforming growth factor beta receptor 2
chr11_-_65121780 3.79 ENST00000525297.5
ENST00000529259.1
FAU ubiquitin like and ribosomal protein S30 fusion
chr16_+_19067989 3.71 ENST00000569127.1
coenzyme Q7, hydroxylase
chrX_+_24693879 3.45 ENST00000379068.8
ENST00000677890.1
ENST00000379059.7
DNA polymerase alpha 1, catalytic subunit
chr11_+_67266437 3.45 ENST00000308595.10
ENST00000526285.1
G protein-coupled receptor kinase 2
chr3_+_11272413 3.41 ENST00000446450.6
ENST00000354956.9
ENST00000354449.7
ENST00000419112.5
autophagy related 7
chr19_+_10871673 3.40 ENST00000344150.8
coactivator associated arginine methyltransferase 1
chr2_+_131476112 3.31 ENST00000321253.7
tubulin alpha 3d
chr1_+_203007364 3.22 ENST00000367242.4
transmembrane protein 183A
chr1_-_1724274 3.02 ENST00000401096.2
ENST00000357760.6
ENST00000358779.9
ENST00000378633.5
ENST00000404249.8
cyclin dependent kinase 11A
chr12_+_120446418 2.84 ENST00000551765.6
ENST00000229384.5
glutamyl-tRNA amidotransferase subunit C

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
60.0 179.9 GO:0075732 viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594)
27.3 82.0 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
21.4 64.2 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
20.1 60.2 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
19.2 57.5 GO:0005999 xylulose biosynthetic process(GO:0005999)
18.7 74.8 GO:0006408 snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
17.7 35.4 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
13.6 149.6 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
11.0 33.0 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
9.9 29.7 GO:0044034 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
7.6 22.9 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
6.6 32.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
6.4 102.5 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
6.4 25.6 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
6.3 18.8 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
6.1 48.8 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
5.7 28.4 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
5.7 17.0 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
5.6 16.8 GO:0009386 translational attenuation(GO:0009386)
5.4 37.8 GO:0060702 negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702)
5.0 35.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
4.6 23.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
4.2 12.7 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
4.0 16.1 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
3.9 15.6 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
3.7 15.0 GO:1903182 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
3.5 17.6 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
3.4 20.3 GO:0048254 snoRNA localization(GO:0048254)
3.2 12.8 GO:0061187 regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
3.2 15.8 GO:0033206 meiotic cytokinesis(GO:0033206)
3.1 15.7 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
2.6 26.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
2.5 74.7 GO:0072663 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
2.5 19.8 GO:0006685 sphingomyelin catabolic process(GO:0006685)
2.3 46.3 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
2.2 26.3 GO:2001138 regulation of phospholipid transport(GO:2001138) positive regulation of phospholipid transport(GO:2001140)
2.1 17.1 GO:2000210 positive regulation of anoikis(GO:2000210)
2.1 27.7 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
2.1 14.6 GO:0080009 mRNA methylation(GO:0080009)
2.1 8.3 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
2.0 19.7 GO:0000012 single strand break repair(GO:0000012)
1.9 17.5 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
1.7 8.6 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
1.6 14.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
1.5 9.0 GO:0016926 protein desumoylation(GO:0016926)
1.5 60.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
1.5 23.4 GO:0045116 protein neddylation(GO:0045116) response to redox state(GO:0051775)
1.5 100.6 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
1.4 5.7 GO:1902775 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
1.4 9.7 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
1.3 101.0 GO:0070125 mitochondrial translational elongation(GO:0070125)
1.3 3.9 GO:0060434 bronchus morphogenesis(GO:0060434)
1.2 11.0 GO:0015693 magnesium ion transport(GO:0015693)
1.2 20.9 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
1.1 3.4 GO:0075071 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
1.1 21.0 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
1.0 37.6 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.9 2.8 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.9 7.0 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.9 1.8 GO:0009106 lipoate metabolic process(GO:0009106)
0.9 104.8 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.9 3.5 GO:0006272 DNA replication, synthesis of RNA primer(GO:0006269) leading strand elongation(GO:0006272)
0.9 29.0 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.9 17.0 GO:0018345 protein palmitoylation(GO:0018345)
0.8 44.8 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.8 4.2 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.8 4.2 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.8 22.9 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.7 15.4 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.7 2.2 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.7 5.6 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.7 30.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.6 15.6 GO:0006491 N-glycan processing(GO:0006491)
0.6 14.3 GO:0000154 rRNA modification(GO:0000154)
0.6 15.8 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.6 33.9 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.5 16.3 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.5 4.0 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.5 20.5 GO:0043631 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.5 2.0 GO:0030047 actin modification(GO:0030047)
0.5 28.7 GO:0014003 oligodendrocyte development(GO:0014003)
0.4 7.6 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.4 3.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.4 34.9 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436)
0.3 3.6 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.3 25.0 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.3 8.8 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.3 29.9 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.3 19.8 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.3 5.2 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.3 2.1 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.3 4.3 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 62.6 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.2 0.9 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.2 2.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.2 34.3 GO:0046718 viral entry into host cell(GO:0046718)
0.2 11.9 GO:0051028 mRNA transport(GO:0051028)
0.2 2.0 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 8.2 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 7.0 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 21.3 GO:0006413 translational initiation(GO:0006413)
0.1 8.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 1.4 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.1 7.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 7.2 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 5.4 GO:0001895 retina homeostasis(GO:0001895)
0.1 0.5 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.1 4.2 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 5.3 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
24.0 120.1 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
18.7 74.8 GO:0005846 nuclear cap binding complex(GO:0005846)
14.6 102.5 GO:0032021 NELF complex(GO:0032021)
14.0 238.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
11.3 34.0 GO:0030689 Noc complex(GO:0030689)
10.7 53.7 GO:0089701 U2AF(GO:0089701)
9.9 128.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
7.0 20.9 GO:0045323 interleukin-1 receptor complex(GO:0045323)
6.8 61.4 GO:0072546 ER membrane protein complex(GO:0072546)
6.3 25.1 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
5.9 29.7 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
5.2 15.7 GO:0035517 PR-DUB complex(GO:0035517)
5.2 46.8 GO:0042382 paraspeckles(GO:0042382)
4.5 31.8 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
4.2 29.5 GO:0044530 supraspliceosomal complex(GO:0044530)
4.1 28.7 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
4.0 16.1 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
3.9 23.4 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
3.7 15.0 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
3.6 14.2 GO:0008537 proteasome activator complex(GO:0008537)
3.0 29.9 GO:0005785 signal recognition particle receptor complex(GO:0005785)
2.9 35.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
2.5 101.0 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
2.3 64.7 GO:0035145 exon-exon junction complex(GO:0035145)
2.3 27.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
2.2 17.8 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
2.2 15.4 GO:0005663 DNA replication factor C complex(GO:0005663)
2.1 17.1 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
1.6 24.5 GO:0000930 gamma-tubulin complex(GO:0000930)
1.6 60.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
1.6 100.6 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
1.5 32.9 GO:0036020 endolysosome membrane(GO:0036020)
1.5 20.6 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
1.4 40.8 GO:0071011 precatalytic spliceosome(GO:0071011)
1.4 37.8 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
1.3 22.9 GO:0030686 90S preribosome(GO:0030686)
1.3 6.7 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
1.3 15.8 GO:0071203 WASH complex(GO:0071203)
1.3 41.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
1.1 30.6 GO:0005680 anaphase-promoting complex(GO:0005680)
1.0 16.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
1.0 11.6 GO:0042405 nuclear inclusion body(GO:0042405)
1.0 11.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.9 2.8 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.8 8.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.8 40.9 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.7 9.7 GO:0017119 Golgi transport complex(GO:0017119)
0.7 18.8 GO:0036452 ESCRT complex(GO:0036452)
0.7 17.1 GO:0070822 Sin3-type complex(GO:0070822)
0.7 7.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.7 28.1 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.6 3.9 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.6 6.2 GO:0051286 cell tip(GO:0051286)
0.6 7.0 GO:0005686 U2 snRNP(GO:0005686)
0.6 3.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.4 43.1 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.4 26.8 GO:0031201 SNARE complex(GO:0031201)
0.4 2.0 GO:0044305 calyx of Held(GO:0044305)
0.4 5.4 GO:0097433 dense body(GO:0097433)
0.4 5.0 GO:0001673 male germ cell nucleus(GO:0001673)
0.3 21.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.3 28.4 GO:0036064 ciliary basal body(GO:0036064)
0.3 2.7 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.2 25.0 GO:0070821 tertiary granule membrane(GO:0070821)
0.2 23.3 GO:0005643 nuclear pore(GO:0005643)
0.2 12.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 3.6 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.2 30.9 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 1.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 12.8 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.1 14.7 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 9.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 3.4 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.1 7.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 6.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 9.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 7.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 16.6 GO:0005681 spliceosomal complex(GO:0005681)
0.1 30.9 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 0.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 43.6 GO:0000139 Golgi membrane(GO:0000139)
0.1 4.2 GO:0005771 multivesicular body(GO:0005771)
0.1 8.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 9.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 12.1 GO:0000790 nuclear chromatin(GO:0000790)
0.0 2.5 GO:0005840 ribosome(GO:0005840)
0.0 11.3 GO:0005667 transcription factor complex(GO:0005667)
0.0 12.0 GO:0005635 nuclear envelope(GO:0005635)
0.0 8.7 GO:0016607 nuclear speck(GO:0016607)
0.0 5.3 GO:0030667 secretory granule membrane(GO:0030667)
0.0 2.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.0 GO:0030175 filopodium(GO:0030175)
0.0 3.0 GO:0019866 mitochondrial inner membrane(GO:0005743) organelle inner membrane(GO:0019866)
0.0 4.2 GO:0005769 early endosome(GO:0005769)
0.0 4.2 GO:0098857 membrane raft(GO:0045121) membrane microdomain(GO:0098857)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
20.1 60.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
14.4 57.5 GO:0004802 transketolase activity(GO:0004802)
11.0 33.0 GO:0070364 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
10.3 215.3 GO:0043495 protein anchor(GO:0043495)
8.8 26.3 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
7.5 74.8 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
6.7 120.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
6.6 19.7 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
6.5 25.8 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
5.9 29.7 GO:0019776 Atg8 ligase activity(GO:0019776)
5.6 28.0 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
5.4 37.8 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
5.4 16.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
5.2 15.6 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
5.1 20.3 GO:0030622 U4atac snRNA binding(GO:0030622)
5.0 29.9 GO:0005047 signal recognition particle binding(GO:0005047)
4.3 82.0 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
3.7 15.0 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
3.7 29.5 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
3.6 14.6 GO:0008174 mRNA methyltransferase activity(GO:0008174)
3.5 28.3 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
3.5 27.8 GO:0050733 RS domain binding(GO:0050733)
3.5 20.9 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
3.3 23.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
2.9 8.8 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
2.3 22.6 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
2.2 15.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
2.2 19.8 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
2.2 15.4 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
2.1 23.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
2.0 14.2 GO:0061133 endopeptidase activator activity(GO:0061133)
1.9 29.0 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
1.9 100.6 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.9 35.2 GO:0051400 BH domain binding(GO:0051400)
1.7 43.8 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
1.7 31.8 GO:0017070 U6 snRNA binding(GO:0017070)
1.6 43.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
1.5 44.8 GO:0008308 voltage-gated anion channel activity(GO:0008308)
1.5 9.0 GO:0016929 SUMO-specific protease activity(GO:0016929)
1.4 32.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
1.4 8.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
1.4 46.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
1.3 3.9 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
1.1 3.4 GO:0031753 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
1.1 63.8 GO:0031593 polyubiquitin binding(GO:0031593)
1.1 51.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
1.0 4.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
1.0 12.4 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
1.0 16.3 GO:0001054 RNA polymerase I activity(GO:0001054)
1.0 15.8 GO:0042809 vitamin D receptor binding(GO:0042809)
0.9 17.0 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.8 11.0 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.8 53.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.7 12.8 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.6 17.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.6 22.9 GO:0000049 tRNA binding(GO:0000049)
0.6 128.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.6 24.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.6 1.8 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.6 11.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.6 3.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.6 6.2 GO:0030911 TPR domain binding(GO:0030911)
0.5 17.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.5 6.9 GO:0019789 SUMO transferase activity(GO:0019789)
0.5 17.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.4 2.1 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.3 23.1 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.3 1.9 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 7.6 GO:0030331 estrogen receptor binding(GO:0030331)
0.3 12.7 GO:0005484 SNAP receptor activity(GO:0005484)
0.3 18.8 GO:0035064 methylated histone binding(GO:0035064)
0.3 23.8 GO:0019905 syntaxin binding(GO:0019905)
0.3 6.7 GO:0030515 snoRNA binding(GO:0030515)
0.2 0.7 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.2 2.0 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.2 18.8 GO:0047485 protein N-terminus binding(GO:0047485)
0.2 13.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.2 3.5 GO:0008408 3'-5' exonuclease activity(GO:0008408)
0.2 95.0 GO:0003682 chromatin binding(GO:0003682)
0.2 9.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 40.4 GO:0030246 carbohydrate binding(GO:0030246)
0.1 28.2 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1 2.2 GO:0031005 filamin binding(GO:0031005)
0.1 30.7 GO:0003924 GTPase activity(GO:0003924)
0.1 4.2 GO:0015485 cholesterol binding(GO:0015485)
0.1 7.2 GO:0015171 amino acid transmembrane transporter activity(GO:0015171)
0.0 8.3 GO:0005178 integrin binding(GO:0005178)
0.0 2.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 45.7 GO:0003723 RNA binding(GO:0003723)
0.0 1.2 GO:0051082 unfolded protein binding(GO:0051082)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.3 210.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
1.4 25.0 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.7 19.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.6 20.9 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.5 72.4 PID E2F PATHWAY E2F transcription factor network
0.4 6.9 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 13.6 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.2 15.4 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 3.9 PID ALK1 PATHWAY ALK1 signaling events
0.1 20.0 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 8.3 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 5.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 8.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.9 PID P53 REGULATION PATHWAY p53 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
8.6 352.2 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
6.8 82.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
3.4 120.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
2.3 20.9 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
2.2 69.7 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
1.8 25.0 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
1.7 26.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.7 31.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
1.3 46.8 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
1.3 30.6 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
1.3 32.9 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
1.2 100.6 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
1.2 8.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
1.0 11.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.9 36.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.8 55.8 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.8 18.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.6 15.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.5 29.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.5 36.3 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.4 19.8 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.3 20.6 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.3 29.5 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.3 15.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.3 9.8 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.3 2.0 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.3 57.5 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.3 40.3 REACTOME TRANSLATION Genes involved in Translation
0.2 3.5 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.2 4.0 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.2 8.8 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.2 15.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.2 3.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 4.2 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.1 3.9 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 2.2 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 5.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 3.6 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production