ISMARA results: CREB3L1

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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for CREB3L1_CREB3

Z-value: 1.67

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Transcription factors associated with CREB3L1_CREB3

Gene Symbol	Gene ID	Gene Info
CREB3L1 Ensembl NCBI GeneCards UniProt	ENSG00000157613.11	CREB3L1
CREB3 Ensembl NCBI GeneCards UniProt	ENSG00000107175.12	CREB3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
CREB3	hg38_v1_chr9_+_35732649_35732685	0.23	5.8e-04	Click!
CREB3L1	hg38_v1_chr11_+_46277648_46277686	0.22	1.1e-03	Click!

Activity profile of CREB3L1_CREB3 motif

Sorted Z-values of CREB3L1_CREB3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB3L1_CREB3

View svg image
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Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr3_+_100492548 Show fit	23.29	ENST00000323523.8 ENST00000403410.5 ENST00000449609.1	TMEM45A Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 45A
chr12_-_106247950 Show fit	23.03	ENST00000378026.5	CKAP4 Ensembl NCBI GeneCards UniProt Show fit	cytoskeleton associated protein 4
chr7_+_128739395 Show fit	22.19	ENST00000479257.5	CALU Ensembl NCBI GeneCards UniProt Show fit	calumenin
chr7_+_128739292 Show fit	21.70	ENST00000535011.6 ENST00000542996.6 ENST00000249364.9 ENST00000449187.6	CALU Ensembl NCBI GeneCards UniProt Show fit	calumenin
chr22_+_38468036 Show fit	21.59	ENST00000409006.3 ENST00000216014.9	KDELR3 Ensembl NCBI GeneCards UniProt Show fit	KDEL endoplasmic reticulum protein retention receptor 3
chr11_+_32091065 Show fit	21.31	ENST00000054950.4	RCN1 Ensembl NCBI GeneCards UniProt Show fit	reticulocalbin 1
chr2_-_69387188 Show fit	18.95	ENST00000674507.1 ENST00000357308.9	GFPT1 Ensembl NCBI GeneCards UniProt Show fit	glutamine--fructose-6-phosphate transaminase 1
chr3_-_57597443 Show fit	18.75	ENST00000463880.1	ARF4 Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor 4
chr19_-_48390847 Show fit	17.96	ENST00000597017.5	KDELR1 Ensembl NCBI GeneCards UniProt Show fit	KDEL endoplasmic reticulum protein retention receptor 1
chrX_+_47582408 Show fit	16.85	ENST00000456754.6 ENST00000218388.9 ENST00000377017.5 ENST00000441738.1	TIMP1 Ensembl NCBI GeneCards UniProt Show fit	TIMP metallopeptidase inhibitor 1
chr2_-_69387241 Show fit	16.59	ENST00000361060.5	GFPT1 Ensembl NCBI GeneCards UniProt Show fit	glutamine--fructose-6-phosphate transaminase 1
chr2_-_69387130 Show fit	16.50	ENST00000674438.1	GFPT1 Ensembl NCBI GeneCards UniProt Show fit	glutamine--fructose-6-phosphate transaminase 1
chr3_-_57597325 Show fit	15.97	ENST00000496292.5 ENST00000489843.1 ENST00000303436.11	ARF4 Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor 4
chr7_+_94394886 Show fit	15.86	ENST00000297268.11 ENST00000620463.1	COL1A2 Ensembl NCBI GeneCards UniProt Show fit	collagen type I alpha 2 chain
chr6_+_116370938 Show fit	14.12	ENST00000644252.3 ENST00000646710.1 ENST00000359564.3	DSE Ensembl NCBI GeneCards UniProt Show fit	dermatan sulfate epimerase
chr1_+_162561504 Show fit	13.86	ENST00000271469.7 ENST00000367926.8	UAP1 Ensembl NCBI GeneCards UniProt Show fit	UDP-N-acetylglucosamine pyrophosphorylase 1
chr19_-_40690629 Show fit	13.13	ENST00000252891.8	NUMBL Ensembl NCBI GeneCards UniProt Show fit	NUMB like endocytic adaptor protein
chr9_+_99222258 Show fit	13.00	ENST00000223641.5	SEC61B Ensembl NCBI GeneCards UniProt Show fit	SEC61 translocon subunit beta
chr5_-_132227472 Show fit	12.87	ENST00000428369.6	P4HA2 Ensembl NCBI GeneCards UniProt Show fit	prolyl 4-hydroxylase subunit alpha 2
chr19_-_4670331 Show fit	12.84	ENST00000262947.8 ENST00000599630.1	MYDGF Ensembl NCBI GeneCards UniProt Show fit	myeloid derived growth factor
chr5_-_132227808 Show fit	12.49	ENST00000401867.5 ENST00000379086.5 ENST00000379100.7 ENST00000418055.5 ENST00000453286.5 ENST00000360568.8 ENST00000379104.7 ENST00000166534.8	P4HA2 Ensembl NCBI GeneCards UniProt Show fit	prolyl 4-hydroxylase subunit alpha 2
chr2_-_241315180 Show fit	12.18	ENST00000441124.5 ENST00000391976.6	HDLBP Ensembl NCBI GeneCards UniProt Show fit	high density lipoprotein binding protein
chr8_-_63026179 Show fit	11.56	ENST00000677919.1	GGH Ensembl NCBI GeneCards UniProt Show fit	gamma-glutamyl hydrolase
chr6_+_31948956 Show fit	11.07	ENST00000483004.1	CFB Ensembl NCBI GeneCards UniProt Show fit	complement factor B
chr9_+_98056694 Show fit	10.97	ENST00000210444.6	NANS Ensembl NCBI GeneCards UniProt Show fit	N-acetylneuraminate synthase
chrX_+_153794635 Show fit	9.96	ENST00000370086.8 ENST00000370085.3	SSR4 Ensembl NCBI GeneCards UniProt Show fit	signal sequence receptor subunit 4
chr12_-_50222694 Show fit	9.60	ENST00000552783.5	LIMA1 Ensembl NCBI GeneCards UniProt Show fit	LIM domain and actin binding 1
chr8_-_70607654 Show fit	9.57	ENST00000521425.5	TRAM1 Ensembl NCBI GeneCards UniProt Show fit	translocation associated membrane protein 1
chr3_+_37861926 Show fit	9.37	ENST00000443503.6	CTDSPL Ensembl NCBI GeneCards UniProt Show fit	CTD small phosphatase like
chrX_+_153794152 Show fit	9.30	ENST00000370087.5	SSR4 Ensembl NCBI GeneCards UniProt Show fit	signal sequence receptor subunit 4
chr12_-_50222348 Show fit	8.96	ENST00000552823.5 ENST00000552909.5	LIMA1 Ensembl NCBI GeneCards UniProt Show fit	LIM domain and actin binding 1
chr8_-_108443409 Show fit	8.90	ENST00000678023.1 ENST00000679198.1 ENST00000678881.1 ENST00000677084.1 ENST00000676663.1 ENST00000677614.1 ENST00000677040.1 ENST00000676487.1 ENST00000677409.1 ENST00000678797.1 ENST00000678334.1	EIF3E Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 3 subunit E
chr3_+_37861849 Show fit	8.85	ENST00000273179.10	CTDSPL Ensembl NCBI GeneCards UniProt Show fit	CTD small phosphatase like
chr5_-_10761156 Show fit	8.50	ENST00000432074.2 ENST00000230895.11	DAP Ensembl NCBI GeneCards UniProt Show fit	death associated protein
chr5_-_39424966 Show fit	8.44	ENST00000515700.5 ENST00000320816.11 ENST00000339788.10	DAB2 Ensembl NCBI GeneCards UniProt Show fit	DAB adaptor protein 2
chr18_-_49491586 Show fit	8.26	ENST00000584895.5 ENST00000580210.5 ENST00000579408.5	RPL17-C18orf32 Ensembl NCBI GeneCards UniProt Show fit RPL17 Ensembl NCBI GeneCards UniProt Show fit	RPL17-C18orf32 readthrough ribosomal protein L17
chr2_+_241315223 Show fit	8.21	ENST00000428282.5 ENST00000360051.7	SEPTIN2 Ensembl NCBI GeneCards UniProt Show fit	septin 2
chr12_-_120201099 Show fit	8.15	ENST00000551150.5 ENST00000313104.9 ENST00000547191.5 ENST00000546989.5 ENST00000392514.9 ENST00000228306.8 ENST00000550856.5	RPLP0 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein lateral stalk subunit P0
chr5_-_39425187 Show fit	8.03	ENST00000545653.5	DAB2 Ensembl NCBI GeneCards UniProt Show fit	DAB adaptor protein 2
chr11_-_62573846 Show fit	8.00	ENST00000329251.5	EEF1G Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation elongation factor 1 gamma
chr2_+_241315092 Show fit	7.98	ENST00000391973.6	SEPTIN2 Ensembl NCBI GeneCards UniProt Show fit	septin 2
chr11_-_14499803 Show fit	7.80	ENST00000439561.7 ENST00000534234.5	COPB1 Ensembl NCBI GeneCards UniProt Show fit	COPI coat complex subunit beta 1
chr2_+_182716227 Show fit	7.68	ENST00000680258.1 ENST00000680667.1 ENST00000264065.12 ENST00000616986.5 ENST00000679884.1	DNAJC10 Ensembl NCBI GeneCards UniProt Show fit	DnaJ heat shock protein family (Hsp40) member C10
chr11_-_14499833 Show fit	7.56	ENST00000249923.7 ENST00000529866.5	COPB1 Ensembl NCBI GeneCards UniProt Show fit	COPI coat complex subunit beta 1
chr20_+_31547367 Show fit	7.52	ENST00000394552.3	MCTS2P Ensembl NCBI GeneCards UniProt Show fit	MCTS family member 2, pseudogene
chr10_-_96586975 Show fit	7.49	ENST00000371142.9	TM9SF3 Ensembl NCBI GeneCards UniProt Show fit	transmembrane 9 superfamily member 3
chr2_+_27032938 Show fit	7.32	ENST00000238788.14 ENST00000404032.7	TMEM214 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 214
chr3_+_123067016 Show fit	6.93	ENST00000316218.12	PDIA5 Ensembl NCBI GeneCards UniProt Show fit	protein disulfide isomerase family A member 5
chr3_-_108222383 Show fit	6.88	ENST00000264538.4	IFT57 Ensembl NCBI GeneCards UniProt Show fit	intraflagellar transport 57
chr10_+_119651372 Show fit	6.83	ENST00000369085.8	BAG3 Ensembl NCBI GeneCards UniProt Show fit	BAG cochaperone 3
chr6_-_7313146 Show fit	6.79	ENST00000489567.5 ENST00000479365.5 ENST00000462112.1 ENST00000397511.6 ENST00000244763.9 ENST00000474597.5 ENST00000650389.1	SSR1 Ensembl NCBI GeneCards UniProt Show fit	signal sequence receptor subunit 1
chr7_-_30026617 Show fit	6.74	ENST00000222803.10	FKBP14 Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase 14
chr19_+_5681140 Show fit	6.49	ENST00000579559.1 ENST00000577222.5	HSD11B1L Ensembl NCBI GeneCards UniProt Show fit RPL36 Ensembl NCBI GeneCards UniProt Show fit	hydroxysteroid 11-beta dehydrogenase 1 like ribosomal protein L36
chr9_+_111631354 Show fit	6.49	ENST00000374294.3	DNAJC25-GNG10 Ensembl NCBI GeneCards UniProt Show fit	DNAJC25-GNG10 readthrough
chr7_-_94004345 Show fit	6.41	ENST00000222547.8 ENST00000433727.5	BET1 Ensembl NCBI GeneCards UniProt Show fit	Bet1 golgi vesicular membrane trafficking protein
chr8_+_63168553 Show fit	6.31	ENST00000617200.1 ENST00000623280.3	YTHDF3 Ensembl NCBI GeneCards UniProt Show fit	YTH N6-methyladenosine RNA binding protein 3
chr2_-_120223371 Show fit	6.30	ENST00000426077.3	TMEM185B Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 185B
chr8_+_63168597 Show fit	6.29	ENST00000539294.6 ENST00000621957.4 ENST00000517371.5 ENST00000621413.4 ENST00000612880.4	YTHDF3 Ensembl NCBI GeneCards UniProt Show fit	YTH N6-methyladenosine RNA binding protein 3
chr6_+_151240368 Show fit	6.16	ENST00000253332.5	AKAP12 Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 12
chr7_+_39623547 Show fit	6.00	ENST00000005257.7	RALA Ensembl NCBI GeneCards UniProt Show fit	RAS like proto-oncogene A
chr5_+_69093943 Show fit	5.88	ENST00000621204.4	SLC30A5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 30 member 5
chr12_-_56315890 Show fit	5.72	ENST00000551286.1 ENST00000549318.5	CNPY2 Ensembl NCBI GeneCards UniProt Show fit ENSG00000144785.8 Ensembl NCBI GeneCards UniProt Show fit	canopy FGF signaling regulator 2 novel protein
chr5_+_66144288 Show fit	5.69	ENST00000334121.11	SREK1 Ensembl NCBI GeneCards UniProt Show fit	splicing regulatory glutamic acid and lysine rich protein 1
chr4_-_118836067 Show fit	5.69	ENST00000280551.11	SEC24D Ensembl NCBI GeneCards UniProt Show fit	SEC24 homolog D, COPII coat complex component
chr12_-_48924919 Show fit	5.54	ENST00000444214.6	FKBP11 Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase 11
chr5_+_149960719 Show fit	5.50	ENST00000286298.5 ENST00000433184.1	SLC26A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 26 member 2
chr6_-_109381739 Show fit	5.43	ENST00000504373.2	CD164 Ensembl NCBI GeneCards UniProt Show fit	CD164 molecule
chr6_+_24775413 Show fit	5.29	ENST00000378054.6 ENST00000620958.4 ENST00000476555.5	GMNN Ensembl NCBI GeneCards UniProt Show fit	geminin DNA replication inhibitor
chr6_+_24774925 Show fit	5.29	ENST00000356509.7 ENST00000230056.8	GMNN Ensembl NCBI GeneCards UniProt Show fit	geminin DNA replication inhibitor
chr5_+_134648772 Show fit	5.17	ENST00000398844.7 ENST00000322887.8	SEC24A Ensembl NCBI GeneCards UniProt Show fit	SEC24 homolog A, COPII coat complex component
chr17_+_18781250 Show fit	5.04	ENST00000476139.5	TVP23B Ensembl NCBI GeneCards UniProt Show fit	trans-golgi network vesicle protein 23 homolog B
chr6_-_100881281 Show fit	4.76	ENST00000369143.2 ENST00000369162.7 ENST00000324723.10 ENST00000522650.5	ASCC3 Ensembl NCBI GeneCards UniProt Show fit	activating signal cointegrator 1 complex subunit 3
chr6_+_151239951 Show fit	4.72	ENST00000402676.7	AKAP12 Ensembl NCBI GeneCards UniProt Show fit	A-kinase anchoring protein 12
chr17_+_7252024 Show fit	4.37	ENST00000573513.5 ENST00000354429.6 ENST00000574255.5 ENST00000356683.6 ENST00000396627.6	ELP5 Ensembl NCBI GeneCards UniProt Show fit	elongator acetyltransferase complex subunit 5
chr12_-_56316002 Show fit	4.36	ENST00000547423.5 ENST00000548360.1 ENST00000551475.5	ENSG00000144785.8 Ensembl NCBI GeneCards UniProt Show fit CNPY2 Ensembl NCBI GeneCards UniProt Show fit	novel protein canopy FGF signaling regulator 2
chrX_-_10576901 Show fit	4.34	ENST00000380779.5	MID1 Ensembl NCBI GeneCards UniProt Show fit	midline 1
chr1_+_173477324 Show fit	4.32	ENST00000340385.6	PRDX6 Ensembl NCBI GeneCards UniProt Show fit	peroxiredoxin 6
chrX_+_154398890 Show fit	4.28	ENST00000406022.6	RPL10 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L10
chr12_-_56315952 Show fit	4.23	ENST00000273308.9	CNPY2 Ensembl NCBI GeneCards UniProt Show fit	canopy FGF signaling regulator 2
chr6_-_73521783 Show fit	4.22	ENST00000331523.7 ENST00000356303.7	EEF1A1 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation elongation factor 1 alpha 1
chr7_-_73770258 Show fit	4.12	ENST00000395145.3	CLDN3 Ensembl NCBI GeneCards UniProt Show fit	claudin 3
chr1_-_153967621 Show fit	4.11	ENST00000413622.5 ENST00000310483.10	SLC39A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 39 member 1
chr3_-_49358320 Show fit	4.07	ENST00000643797.1 ENST00000646881.2 ENST00000496791.2	GPX1 Ensembl NCBI GeneCards UniProt Show fit	glutathione peroxidase 1
chr5_-_126595237 Show fit	4.03	ENST00000637206.1 ENST00000553117.5	ALDH7A1 Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 7 family member A1
chr8_-_29350666 Show fit	3.97	ENST00000240100.7	DUSP4 Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 4
chr16_+_56657924 Show fit	3.97	ENST00000334350.7	MT1F Ensembl NCBI GeneCards UniProt Show fit	metallothionein 1F
chr19_+_49527988 Show fit	3.95	ENST00000270645.8	RCN3 Ensembl NCBI GeneCards UniProt Show fit	reticulocalbin 3
chr21_-_37073019 Show fit	3.90	ENST00000360525.9	PIGP Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol glycan anchor biosynthesis class P
chr17_-_15563428 Show fit	3.85	ENST00000584811.5 ENST00000419890.3 ENST00000518321.6 ENST00000438826.7 ENST00000225576.7 ENST00000428082.6 ENST00000522212.6	TVP23C Ensembl NCBI GeneCards UniProt Show fit TVP23C-CDRT4 Ensembl NCBI GeneCards UniProt Show fit	trans-golgi network vesicle protein 23 homolog C TVP23C-CDRT4 readthrough
chr9_+_114587706 Show fit	3.83	ENST00000677115.1 ENST00000677452.1 ENST00000374050.4 ENST00000677498.1 ENST00000679150.1	ATP6V1G1 Ensembl NCBI GeneCards UniProt Show fit	ATPase H+ transporting V1 subunit G1
chr1_-_119140628 Show fit	3.83	ENST00000369426.9 ENST00000235521.5	WARS2 Ensembl NCBI GeneCards UniProt Show fit	tryptophanyl tRNA synthetase 2, mitochondrial
chr17_+_7252237 Show fit	3.83	ENST00000570500.5	ELP5 Ensembl NCBI GeneCards UniProt Show fit	elongator acetyltransferase complex subunit 5
chr7_+_16753731 Show fit	3.83	ENST00000262067.5	TSPAN13 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 13
chr4_-_121823843 Show fit	3.76	ENST00000274026.10	CCNA2 Ensembl NCBI GeneCards UniProt Show fit	cyclin A2
chr12_+_52069967 Show fit	3.75	ENST00000336854.9 ENST00000550604.1 ENST00000553049.5 ENST00000548915.1	ATG101 Ensembl NCBI GeneCards UniProt Show fit	autophagy related 101
chrX_-_103686687 Show fit	3.66	ENST00000441076.7 ENST00000422355.5 ENST00000442614.5 ENST00000451301.5	MORF4L2 Ensembl NCBI GeneCards UniProt Show fit	mortality factor 4 like 2
chr2_+_170929198 Show fit	3.64	ENST00000234160.5	GORASP2 Ensembl NCBI GeneCards UniProt Show fit	golgi reassembly stacking protein 2
chr6_+_151452447 Show fit	3.59	ENST00000367294.4	ARMT1 Ensembl NCBI GeneCards UniProt Show fit	acidic residue methyltransferase 1
chr16_+_56608577 Show fit	3.59	ENST00000245185.6 ENST00000561491.1	MT2A Ensembl NCBI GeneCards UniProt Show fit	metallothionein 2A
chr8_+_22565236 Show fit	3.58	ENST00000523900.5	SORBS3 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 3
chr18_-_49492305 Show fit	3.56	ENST00000615479.4 ENST00000583637.5 ENST00000618613.5 ENST00000615760.4 ENST00000578528.1 ENST00000578532.5 ENST00000580387.5 ENST00000579248.5 ENST00000580261.6 ENST00000581373.5 ENST00000618619.4 ENST00000617346.4 ENST00000583036.5 ENST00000332968.11	RPL17 Ensembl NCBI GeneCards UniProt Show fit RPL17-C18orf32 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L17 RPL17-C18orf32 readthrough
chr19_+_797392 Show fit	3.54	ENST00000627714.2 ENST00000349038.8 ENST00000586481.5	PTBP1 Ensembl NCBI GeneCards UniProt Show fit	polypyrimidine tract binding protein 1
chr3_+_133573637 Show fit	3.52	ENST00000264993.8	CDV3 Ensembl NCBI GeneCards UniProt Show fit	CDV3 homolog
chr16_+_56657999 Show fit	3.50	ENST00000568475.1	MT1F Ensembl NCBI GeneCards UniProt Show fit	metallothionein 1F
chr8_+_108443601 Show fit	3.48	ENST00000524143.5 ENST00000220853.8	EMC2 Ensembl NCBI GeneCards UniProt Show fit	ER membrane protein complex subunit 2
chr8_+_132775340 Show fit	3.47	ENST00000622263.4 ENST00000220847.8 ENST00000395379.5 ENST00000395386.7 ENST00000485595.5 ENST00000337920.8	PHF20L1 Ensembl NCBI GeneCards UniProt Show fit	PHD finger protein 20 like 1
chr11_+_118572373 Show fit	3.46	ENST00000392859.7 ENST00000264028.5 ENST00000614498.4 ENST00000359415.8 ENST00000534182.2	ARCN1 Ensembl NCBI GeneCards UniProt Show fit	archain 1
chr2_-_33599269 Show fit	3.44	ENST00000431950.1 ENST00000403368.1 ENST00000238823.13	FAM98A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 98 member A
chr19_+_797443 Show fit	3.41	ENST00000356948.11 ENST00000394601.8 ENST00000589575.5 ENST00000587191.3	PTBP1 Ensembl NCBI GeneCards UniProt Show fit	polypyrimidine tract binding protein 1
chr14_-_49620594 Show fit	3.30	ENST00000298289.7	RPL36AL Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L36a like
chr17_+_7252268 Show fit	3.29	ENST00000396628.6 ENST00000574993.5 ENST00000573657.5	ELP5 Ensembl NCBI GeneCards UniProt Show fit	elongator acetyltransferase complex subunit 5
chr3_-_121749704 Show fit	3.24	ENST00000393667.7 ENST00000340645.9 ENST00000614479.4	GOLGB1 Ensembl NCBI GeneCards UniProt Show fit	golgin B1
chr3_-_49358272 Show fit	3.23	ENST00000419349.2	GPX1 Ensembl NCBI GeneCards UniProt Show fit	glutathione peroxidase 1
chr20_-_17682234 Show fit	3.21	ENST00000377813.6 ENST00000377807.6 ENST00000360807.8 ENST00000398782.2	RRBP1 Ensembl NCBI GeneCards UniProt Show fit	ribosome binding protein 1
chr19_+_49677228 Show fit	3.18	ENST00000454376.7 ENST00000524771.5	PRMT1 Ensembl NCBI GeneCards UniProt Show fit	protein arginine methyltransferase 1
chr3_-_49358340 Show fit	3.14	ENST00000419783.3	GPX1 Ensembl NCBI GeneCards UniProt Show fit	glutathione peroxidase 1
chr1_-_64966488 Show fit	3.02	ENST00000342505.5 ENST00000673254.1	JAK1 Ensembl NCBI GeneCards UniProt Show fit	Janus kinase 1
chr1_+_32180044 Show fit	3.00	ENST00000373609.1	TXLNA Ensembl NCBI GeneCards UniProt Show fit	taxilin alpha
chr10_-_70170466 Show fit	2.99	ENST00000373239.2 ENST00000373241.9 ENST00000373242.6	SAR1A Ensembl NCBI GeneCards UniProt Show fit	secretion associated Ras related GTPase 1A
chr10_+_87863595 Show fit	2.94	ENST00000371953.8	PTEN Ensembl NCBI GeneCards UniProt Show fit	phosphatase and tensin homolog
chr11_-_3797746 Show fit	2.86	ENST00000359171.8	NUP98 Ensembl NCBI GeneCards UniProt Show fit	nucleoporin 98 and 96 precursor
chr2_+_197500371 Show fit	2.86	ENST00000409468.1 ENST00000233893.10	HSPE1 Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family E (Hsp10) member 1
chr5_-_95554944 Show fit	2.83	ENST00000513823.5 ENST00000649566.1 ENST00000358746.7 ENST00000514952.5	TTC37 Ensembl NCBI GeneCards UniProt Show fit	tetratricopeptide repeat domain 37
chr12_+_56158343 Show fit	2.83	ENST00000548580.5 ENST00000293422.9 ENST00000348108.8 ENST00000549017.5 ENST00000549566.5 ENST00000550697.6 ENST00000536128.5 ENST00000547649.5 ENST00000547408.5 ENST00000551589.5 ENST00000549392.5 ENST00000548400.5 ENST00000548293.5	MYL6 Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 6
chr6_+_32969345 Show fit	2.81	ENST00000678250.1	BRD2 Ensembl NCBI GeneCards UniProt Show fit	bromodomain containing 2
chr7_-_101217569 Show fit	2.76	ENST00000223127.8	PLOD3 Ensembl NCBI GeneCards UniProt Show fit	procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
chr11_-_18322122 Show fit	2.75	ENST00000349215.8 ENST00000396253.7 ENST00000438420.6	HPS5 Ensembl NCBI GeneCards UniProt Show fit	HPS5 biogenesis of lysosomal organelles complex 2 subunit 2
chr1_-_43367689 Show fit	2.73	ENST00000621943.4	ELOVL1 Ensembl NCBI GeneCards UniProt Show fit	ELOVL fatty acid elongase 1
chr19_+_49677055 Show fit	2.71	ENST00000534465.6 ENST00000391851.8 ENST00000610806.4	PRMT1 Ensembl NCBI GeneCards UniProt Show fit	protein arginine methyltransferase 1
chr3_-_25783434 Show fit	2.69	ENST00000396649.7 ENST00000280700.10 ENST00000428257.5	NGLY1 Ensembl NCBI GeneCards UniProt Show fit	N-glycanase 1
chr1_+_32179665 Show fit	2.67	ENST00000373610.8	TXLNA Ensembl NCBI GeneCards UniProt Show fit	taxilin alpha
chr9_-_72365198 Show fit	2.66	ENST00000376962.10 ENST00000376960.8	ZFAND5 Ensembl NCBI GeneCards UniProt Show fit	zinc finger AN1-type containing 5
chr15_+_78873030 Show fit	2.65	ENST00000558502.5	MORF4L1 Ensembl NCBI GeneCards UniProt Show fit	mortality factor 4 like 1
chr7_+_23105747 Show fit	2.64	ENST00000322275.9 ENST00000339077.10	KLHL7 Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 7
chr2_-_197435002 Show fit	2.63	ENST00000335508.11 ENST00000414963.2 ENST00000487698.5	SF3B1 Ensembl NCBI GeneCards UniProt Show fit	splicing factor 3b subunit 1
chr1_-_33431079 Show fit	2.63	ENST00000683057.1	PHC2 Ensembl NCBI GeneCards UniProt Show fit	polyhomeotic homolog 2
chr19_-_42255119 Show fit	2.55	ENST00000222329.9 ENST00000594664.1	ERF Ensembl NCBI GeneCards UniProt Show fit ENSG00000268643.2 Ensembl NCBI GeneCards UniProt Show fit	ETS2 repressor factor novel protein
chr14_-_34875348 Show fit	2.40	ENST00000360310.6	BAZ1A Ensembl NCBI GeneCards UniProt Show fit	bromodomain adjacent to zinc finger domain 1A
chr5_+_127517611 Show fit	2.40	ENST00000296666.13 ENST00000442138.6 ENST00000512635.2	PRRC1 Ensembl NCBI GeneCards UniProt Show fit	proline rich coiled-coil 1
chr11_+_809961 Show fit	2.40	ENST00000321153.9 ENST00000530797.5	RPLP2 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein lateral stalk subunit P2
chr19_-_3985451 Show fit	2.35	ENST00000309311.7	EEF2 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation elongation factor 2
chr6_+_32969165 Show fit	2.33	ENST00000496118.2 ENST00000449085.4	BRD2 Ensembl NCBI GeneCards UniProt Show fit	bromodomain containing 2
chr11_-_3797458 Show fit	2.30	ENST00000355260.7	NUP98 Ensembl NCBI GeneCards UniProt Show fit	nucleoporin 98 and 96 precursor
chr11_-_119101814 Show fit	2.28	ENST00000682791.1 ENST00000639704.1 ENST00000354202.9	DPAGT1 Ensembl NCBI GeneCards UniProt Show fit	dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
chr10_-_119080794 Show fit	2.27	ENST00000369144.8 ENST00000541549.2	EIF3A Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 3 subunit A
chr17_+_7252502 Show fit	2.26	ENST00000570322.5 ENST00000576496.5 ENST00000574841.2	ELP5 Ensembl NCBI GeneCards UniProt Show fit	elongator acetyltransferase complex subunit 5
chr20_+_23350755 Show fit	2.22	ENST00000254998.3	NXT1 Ensembl NCBI GeneCards UniProt Show fit	nuclear transport factor 2 like export factor 1
chr1_-_64966284 Show fit	2.20	ENST00000671929.1 ENST00000673046.1 ENST00000672247.1	JAK1 Ensembl NCBI GeneCards UniProt Show fit	Janus kinase 1
chr14_+_55051639 Show fit	2.19	ENST00000395468.9 ENST00000622254.1	MAPK1IP1L Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase 1 interacting protein 1 like
chr5_-_55307540 Show fit	2.17	ENST00000508346.1 ENST00000621106.4 ENST00000251636.10	DHX29 Ensembl NCBI GeneCards UniProt Show fit	DExH-box helicase 29
chr3_-_156555083 Show fit	2.13	ENST00000265044.7 ENST00000476217.5	SSR3 Ensembl NCBI GeneCards UniProt Show fit	signal sequence receptor subunit 3
chr11_-_119057185 Show fit	2.10	ENST00000614668.4 ENST00000617285.5	HYOU1 Ensembl NCBI GeneCards UniProt Show fit	hypoxia up-regulated 1
chr6_-_107958165 Show fit	2.06	ENST00000369002.9	SEC63 Ensembl NCBI GeneCards UniProt Show fit	SEC63 homolog, protein translocation regulator
chr9_-_124941054 Show fit	2.06	ENST00000373555.9	GOLGA1 Ensembl NCBI GeneCards UniProt Show fit	golgin A1
chr14_+_30622304 Show fit	2.04	ENST00000676658.1 ENST00000679165.1 ENST00000676509.1 ENST00000678716.1 ENST00000678402.1 ENST00000678124.1 ENST00000677413.1 ENST00000553693.6 ENST00000469043.2 ENST00000676954.1 ENST00000676812.1 ENST00000678669.1 ENST00000676520.1 ENST00000557076.6 ENST00000544052.6 ENST00000458591.7 ENST00000677340.1 ENST00000676674.1 ENST00000396629.6 ENST00000678579.1	SCFD1 Ensembl NCBI GeneCards UniProt Show fit	sec1 family domain containing 1
chr21_+_43719095 Show fit	2.00	ENST00000468090.5 ENST00000291565.9	PDXK Ensembl NCBI GeneCards UniProt Show fit	pyridoxal kinase
chr11_-_119057105 Show fit	2.00	ENST00000534233.5 ENST00000614711.4 ENST00000530467.5 ENST00000621959.4 ENST00000532519.6 ENST00000532421.5 ENST00000610597.1 ENST00000612687.4	HYOU1 Ensembl NCBI GeneCards UniProt Show fit	hypoxia up-regulated 1
chr7_+_151232464 Show fit	2.00	ENST00000482173.5 ENST00000495645.5 ENST00000035307.6	CHPF2 Ensembl NCBI GeneCards UniProt Show fit	chondroitin polymerizing factor 2
chr11_-_6481350 Show fit	1.97	ENST00000423813.6 ENST00000614314.4	ARFIP2 Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor interacting protein 2
chr11_-_119057218 Show fit	1.96	ENST00000652093.1	HYOU1 Ensembl NCBI GeneCards UniProt Show fit	hypoxia up-regulated 1
chr14_-_77761132 Show fit	1.96	ENST00000554775.5 ENST00000261531.12 ENST00000555761.5 ENST00000554324.1	SNW1 Ensembl NCBI GeneCards UniProt Show fit	SNW domain containing 1
chr3_-_119240870 Show fit	1.93	ENST00000467604.5 ENST00000393765.7 ENST00000491906.5 ENST00000475803.5 ENST00000479150.5 ENST00000470111.5 ENST00000459820.5 ENST00000459778.5 ENST00000359213.7	B4GALT4 Ensembl NCBI GeneCards UniProt Show fit	beta-1,4-galactosyltransferase 4
chr16_-_66925526 Show fit	1.91	ENST00000299759.11 ENST00000420652.5	RRAD Ensembl NCBI GeneCards UniProt Show fit	RRAD, Ras related glycolysis inhibitor and calcium channel regulator
chr11_-_61816985 Show fit	1.91	ENST00000350997.12	FADS1 Ensembl NCBI GeneCards UniProt Show fit	fatty acid desaturase 1
chr6_-_31970923 Show fit	1.91	ENST00000495340.5	DXO Ensembl NCBI GeneCards UniProt Show fit	decapping exoribonuclease
chr6_+_63211446 Show fit	1.90	ENST00000370659.1	FKBP1C Ensembl NCBI GeneCards UniProt Show fit	FKBP prolyl isomerase family member 1C
chr1_-_43367956 Show fit	1.89	ENST00000372458.8	ELOVL1 Ensembl NCBI GeneCards UniProt Show fit	ELOVL fatty acid elongase 1
chr17_+_28744034 Show fit	1.86	ENST00000444415.7 ENST00000262396.10	TRAF4 Ensembl NCBI GeneCards UniProt Show fit	TNF receptor associated factor 4
chr14_-_34874887 Show fit	1.86	ENST00000382422.6	BAZ1A Ensembl NCBI GeneCards UniProt Show fit	bromodomain adjacent to zinc finger domain 1A
chr16_+_81007189 Show fit	1.85	ENST00000439957.7 ENST00000305850.10 ENST00000393335.7 ENST00000428963.6 ENST00000564669.5	CENPN Ensembl NCBI GeneCards UniProt Show fit	centromere protein N
chr3_+_129249594 Show fit	1.84	ENST00000314797.10	COPG1 Ensembl NCBI GeneCards UniProt Show fit	COPI coat complex subunit gamma 1
chr13_-_30465923 Show fit	1.84	ENST00000341423.10 ENST00000326004.4	HMGB1 Ensembl NCBI GeneCards UniProt Show fit	high mobility group box 1
chr12_+_49961864 Show fit	1.83	ENST00000293599.7	AQP5 Ensembl NCBI GeneCards UniProt Show fit	aquaporin 5
chr11_+_125625967 Show fit	1.83	ENST00000428830.6 ENST00000278916.8 ENST00000544373.5 ENST00000532669.5 ENST00000527013.6 ENST00000526937.5 ENST00000534685.5	CHEK1 Ensembl NCBI GeneCards UniProt Show fit	checkpoint kinase 1
chr11_-_6481304 Show fit	1.83	ENST00000254584.6 ENST00000525235.1 ENST00000396777.8 ENST00000445086.6	ARFIP2 Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor interacting protein 2
chr5_+_55307979 Show fit	1.80	ENST00000230640.10	MTREX Ensembl NCBI GeneCards UniProt Show fit	Mtr4 exosome RNA helicase
chr10_-_109923428 Show fit	1.79	ENST00000403138.6 ENST00000369683.5 ENST00000502935.6 ENST00000322238.12	XPNPEP1 Ensembl NCBI GeneCards UniProt Show fit	X-prolyl aminopeptidase 1
chr4_-_47463649 Show fit	1.79	ENST00000381571.6	COMMD8 Ensembl NCBI GeneCards UniProt Show fit	COMM domain containing 8
chr20_-_17682060 Show fit	1.76	ENST00000455029.3	RRBP1 Ensembl NCBI GeneCards UniProt Show fit	ribosome binding protein 1
chr2_-_130129222 Show fit	1.75	ENST00000409914.7	POTEF Ensembl NCBI GeneCards UniProt Show fit	POTE ankyrin domain family member F
chr1_+_42456090 Show fit	1.69	ENST00000372562.1	PPCS Ensembl NCBI GeneCards UniProt Show fit	phosphopantothenoylcysteine synthetase
chr10_-_43407769 Show fit	1.69	ENST00000357065.8	HNRNPF Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein F
chr7_+_130380339 Show fit	1.68	ENST00000481342.5 ENST00000604896.5 ENST00000011292.8	CPA1 Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase A1
chr17_+_59565598 Show fit	1.67	ENST00000251241.9 ENST00000425628.7 ENST00000584385.5 ENST00000580030.1	DHX40 Ensembl NCBI GeneCards UniProt Show fit	DEAH-box helicase 40
chr12_-_104958268 Show fit	1.61	ENST00000432951.1 ENST00000258538.8 ENST00000415674.1 ENST00000424946.1 ENST00000433540.5	SLC41A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 41 member 2
chr4_-_67701113 Show fit	1.59	ENST00000420827.2 ENST00000322244.10	UBA6 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin like modifier activating enzyme 6
chr1_+_151399557 Show fit	1.53	ENST00000290541.7	PSMB4 Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit beta 4
chr3_-_195543308 Show fit	1.52	ENST00000618156.5	PPP1R2 Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory inhibitor subunit 2
chr8_+_22565655 Show fit	1.51	ENST00000523965.5	SORBS3 Ensembl NCBI GeneCards UniProt Show fit	sorbin and SH3 domain containing 3
chr16_-_68236069 Show fit	1.51	ENST00000473183.7 ENST00000565858.5	ESRP2 Ensembl NCBI GeneCards UniProt Show fit	epithelial splicing regulatory protein 2
chr17_+_68515399 Show fit	1.49	ENST00000588188.6	PRKAR1A Ensembl NCBI GeneCards UniProt Show fit	protein kinase cAMP-dependent type I regulatory subunit alpha
chr4_-_110623051 Show fit	1.48	ENST00000557119.2 ENST00000644743.1	PITX2 Ensembl NCBI GeneCards UniProt Show fit	paired like homeodomain 2
chr16_+_53130921 Show fit	1.47	ENST00000564845.5	CHD9 Ensembl NCBI GeneCards UniProt Show fit	chromodomain helicase DNA binding protein 9
chr6_-_89352706 Show fit	1.45	ENST00000435041.3	UBE2J1 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 J1
chr6_-_73521549 Show fit	1.42	ENST00000676547.1	EEF1A1 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation elongation factor 1 alpha 1
chr11_+_3797819 Show fit	1.42	ENST00000396986.6 ENST00000300730.10 ENST00000396993.8 ENST00000532523.5 ENST00000459679.5 ENST00000464229.5 ENST00000464261.5 ENST00000490830.5 ENST00000464906.6 ENST00000464441.5	PGAP2 Ensembl NCBI GeneCards UniProt Show fit	post-GPI attachment to proteins 2
chr4_+_109815503 Show fit	1.41	ENST00000394631.7	GAR1 Ensembl NCBI GeneCards UniProt Show fit	GAR1 ribonucleoprotein
chr1_-_112956063 Show fit	1.39	ENST00000538576.5 ENST00000369626.8 ENST00000458229.6	SLC16A1 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 16 member 1
chrX_+_102599168 Show fit	1.34	ENST00000246174.6	ARMCX5 Ensembl NCBI GeneCards UniProt Show fit	armadillo repeat containing X-linked 5
chr8_+_60678705 Show fit	1.33	ENST00000423902.7	CHD7 Ensembl NCBI GeneCards UniProt Show fit	chromodomain helicase DNA binding protein 7

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.5	16.5	GO:0035026	leading edge cell differentiation(GO:0035026)
4.0	39.5	GO:0006621	protein retention in ER lumen(GO:0006621)
3.9	66.0	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
3.9	34.7	GO:0031584	activation of phospholipase D activity(GO:0031584)
3.5	10.4	GO:1902905	positive regulation of fibril organization(GO:1902905)
3.1	15.4	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
2.9	11.6	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
2.8	16.8	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
2.3	2.3	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
2.1	10.6	GO:0071163	DNA replication preinitiation complex assembly(GO:0071163)
1.5	6.1	GO:0036483	neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0036483) regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903381) negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903382)
1.4	14.3	GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
1.4	25.4	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
1.3	4.0	GO:0019285	glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
1.3	3.8	GO:0071373	cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373)
1.1	15.9	GO:0043589	skin morphogenesis(GO:0043589)
1.1	5.5	GO:0050428	purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
1.0	6.1	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
1.0	8.9	GO:1902416	positive regulation of mRNA binding(GO:1902416)
0.9	10.9	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.9	3.6	GO:0010273	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.9	3.5	GO:0021691	cerebellar Purkinje cell layer maturation(GO:0021691)
0.9	13.7	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.8	11.0	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
0.8	5.9	GO:0045653	histone H4-R3 methylation(GO:0043985) negative regulation of megakaryocyte differentiation(GO:0045653) positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.8	13.1	GO:0021670	lateral ventricle development(GO:0021670)
0.8	3.3	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.8	7.1	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.8	11.7	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.7	2.9	GO:1903121	rhythmic synaptic transmission(GO:0060024) regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.7	5.7	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.7	2.1	GO:0000454	snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.7	2.8	GO:0046947	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.7	2.0	GO:0042822	pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.7	5.3	GO:0061088	regulation of sequestering of zinc ion(GO:0061088)
0.7	2.0	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350) positive regulation of response to alcohol(GO:1901421)
0.6	12.2	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.6	1.9	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.6	1.8	GO:0015670	carbon dioxide transport(GO:0015670)
0.6	4.8	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.6	14.1	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.6	2.4	GO:2000767	positive regulation of cytoplasmic translation(GO:2000767)
0.6	5.2	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
0.5	11.1	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.5	6.0	GO:0051665	membrane raft localization(GO:0051665)
0.5	1.5	GO:0060577	subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.5	7.0	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.5	1.8	GO:2000426	plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
0.5	2.3	GO:0019348	dolichol metabolic process(GO:0019348)
0.4	1.3	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.4	1.7	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.4	12.6	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.4	6.8	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.3	29.0	GO:0036498	IRE1-mediated unfolded protein response(GO:0036498)
0.3	7.5	GO:0071294	cellular response to zinc ion(GO:0071294)
0.3	1.6	GO:0021764	amygdala development(GO:0021764)
0.3	6.5	GO:0060972	left/right pattern formation(GO:0060972)
0.3	22.4	GO:0031529	ruffle organization(GO:0031529)
0.3	4.3	GO:0035372	protein localization to microtubule(GO:0035372)
0.3	46.0	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.3	2.0	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.3	5.6	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.3	3.7	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.3	4.0	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.3	14.7	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
0.2	4.1	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.2	6.3	GO:0043968	histone H2A acetylation(GO:0043968)
0.2	4.3	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2	1.5	GO:1904153	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.2	1.5	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.2	3.9	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.2	1.4	GO:0035879	plasma membrane lactate transport(GO:0035879)
0.2	0.8	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.2	2.9	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.2	3.8	GO:0036295	cellular response to increased oxygen levels(GO:0036295)
0.2	2.7	GO:0090073	positive regulation of protein homodimerization activity(GO:0090073)
0.2	85.0	GO:0043687	post-translational protein modification(GO:0043687)
0.2	1.0	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
0.1	2.0	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.1	1.0	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1	7.4	GO:0018208	peptidyl-proline modification(GO:0018208)
0.1	1.8	GO:0010815	bradykinin catabolic process(GO:0010815)
0.1	4.1	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1	1.4	GO:0002778	antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
0.1	1.9	GO:0071028	nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1	8.5	GO:0010507	negative regulation of autophagy(GO:0010507)
0.1	0.9	GO:0032472	Golgi calcium ion transport(GO:0032472)
0.1	1.9	GO:0036109	alpha-linolenic acid metabolic process(GO:0036109)
0.1	3.0	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1	0.8	GO:0045144	meiotic sister chromatid segregation(GO:0045144)
0.1	1.8	GO:0051683	establishment of Golgi localization(GO:0051683)
0.1	1.6	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.1	14.9	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.1	1.5	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835) negative regulation of activated T cell proliferation(GO:0046007)
0.1	5.4	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1	1.0	GO:0036158	outer dynein arm assembly(GO:0036158)
0.1	5.1	GO:0051496	positive regulation of stress fiber assembly(GO:0051496)
0.1	7.2	GO:0000380	alternative mRNA splicing, via spliceosome(GO:0000380)
0.1	8.0	GO:0006749	glutathione metabolic process(GO:0006749)
0.1	1.4	GO:0006506	GPI anchor metabolic process(GO:0006505) GPI anchor biosynthetic process(GO:0006506)
0.1	1.4	GO:0010867	positive regulation of triglyceride biosynthetic process(GO:0010867)
0.1	2.7	GO:0003016	respiratory system process(GO:0003016)
0.1	0.3	GO:0061188	regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.1	0.2	GO:0051039	histone displacement(GO:0001207) positive regulation of transcription involved in meiotic cell cycle(GO:0051039)
0.1	0.9	GO:0007220	Notch receptor processing(GO:0007220)
0.1	1.7	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.1	1.0	GO:0016180	snRNA processing(GO:0016180)
0.1	1.9	GO:0031055	chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1	2.2	GO:0018146	keratan sulfate biosynthetic process(GO:0018146)
0.1	0.4	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.1	0.2	GO:0002874	regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) regulation of interleukin-18 production(GO:0032661)
0.1	0.2	GO:1901895	negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0	2.6	GO:0045815	positive regulation of gene expression, epigenetic(GO:0045815)
0.0	2.8	GO:0033275	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.0	3.8	GO:0001570	vasculogenesis(GO:0001570)
0.0	2.9	GO:0006334	nucleosome assembly(GO:0006334)
0.0	1.0	GO:0042438	melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.0	1.6	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.0	0.6	GO:0046827	positive regulation of protein export from nucleus(GO:0046827)
0.0	2.6	GO:0006338	chromatin remodeling(GO:0006338)
0.0	1.7	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.4	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	1.5	GO:0005977	glycogen metabolic process(GO:0005977)
0.0	0.6	GO:0045022	early endosome to late endosome transport(GO:0045022)
0.0	0.3	GO:0038003	opioid receptor signaling pathway(GO:0038003)
0.0	0.4	GO:0070584	mitochondrion morphogenesis(GO:0070584)
0.0	0.7	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.2	GO:0046548	retinal rod cell development(GO:0046548)
0.0	1.7	GO:0016241	regulation of macroautophagy(GO:0016241)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
5.4	32.3	GO:0005784	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
4.4	43.9	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
2.7	16.5	GO:0070022	transforming growth factor beta receptor homodimeric complex(GO:0070022)
2.2	36.0	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
1.4	4.3	GO:0008623	CHRAC(GO:0008623)
1.2	13.7	GO:0033588	Elongator holoenzyme complex(GO:0033588)
1.2	15.9	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
1.0	23.0	GO:0042599	lamellar body(GO:0042599)
0.9	2.8	GO:0055087	Ski complex(GO:0055087)
0.9	13.7	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.9	6.1	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.7	12.0	GO:0030127	COPII vesicle coat(GO:0030127)
0.7	9.0	GO:0097413	Lewy body(GO:0097413)
0.6	3.8	GO:0001940	male pronucleus(GO:0001940)
0.6	6.9	GO:0044292	dendrite terminus(GO:0044292)
0.6	3.4	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.5	5.6	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.4	2.1	GO:0072588	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.4	11.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.4	3.9	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.4	5.9	GO:0034709	methylosome(GO:0034709)
0.4	1.4	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
0.4	37.6	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.3	22.1	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.3	12.2	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.3	0.8	GO:0000939	condensed chromosome inner kinetochore(GO:0000939)
0.3	88.6	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.3	8.9	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.2	2.9	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.2	0.6	GO:0070695	FHF complex(GO:0070695)
0.2	2.4	GO:0042788	polysomal ribosome(GO:0042788)
0.2	6.3	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2	2.0	GO:0071014	cyclin/CDK positive transcription elongation factor complex(GO:0008024) post-mRNA release spliceosomal complex(GO:0071014)
0.2	0.4	GO:0098559	cytoplasmic side of early endosome membrane(GO:0098559)
0.2	10.0	GO:0005801	cis-Golgi network(GO:0005801)
0.2	2.6	GO:0035102	PRC1 complex(GO:0035102)
0.2	7.3	GO:0005881	cytoplasmic microtubule(GO:0005881)
0.2	13.6	GO:0035580	specific granule lumen(GO:0035580)
0.2	2.1	GO:0005689	U2 snRNP(GO:0005686) U12-type spliceosomal complex(GO:0005689)
0.1	31.0	GO:0043197	dendritic spine(GO:0043197)
0.1	2.8	GO:0016461	unconventional myosin complex(GO:0016461)
0.1	1.0	GO:0036157	outer dynein arm(GO:0036157)
0.1	4.1	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.1	1.5	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.1	2.8	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.1	1.5	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
0.1	0.9	GO:0070765	gamma-secretase complex(GO:0070765)
0.1	2.2	GO:0031082	BLOC complex(GO:0031082)
0.1	1.0	GO:0045009	melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1	1.5	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.1	1.7	GO:0000800	lateral element(GO:0000800)
0.1	6.2	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	1.0	GO:0032039	integrator complex(GO:0032039)
0.1	1.5	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.1	13.1	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.1	0.9	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.1	0.8	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1	38.8	GO:0000139	Golgi membrane(GO:0000139)
0.1	1.2	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.1	10.3	GO:0072562	blood microparticle(GO:0072562)
0.1	0.6	GO:0005638	lamin filament(GO:0005638)
0.0	0.8	GO:0097431	mitotic spindle pole(GO:0097431)
0.0	2.6	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	8.6	GO:0005681	spliceosomal complex(GO:0005681)
0.0	1.8	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.2	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0	6.8	GO:0030018	Z disc(GO:0030018)
0.0	0.1	GO:0070876	SOSS complex(GO:0070876)
0.0	5.3	GO:0030667	secretory granule membrane(GO:0030667)
0.0	2.2	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	3.1	GO:0035578	azurophil granule lumen(GO:0035578)
0.0	2.8	GO:0005643	nuclear pore(GO:0005643)
0.0	1.8	GO:0005902	microvillus(GO:0005902)
0.0	4.1	GO:0005875	microtubule associated complex(GO:0005875)
0.0	11.8	GO:0005925	focal adhesion(GO:0005925)
0.0	1.5	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.0	0.4	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0	38.6	GO:0070062	extracellular exosome(GO:0070062)
0.0	8.5	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	0.6	GO:0001669	acrosomal vesicle(GO:0001669)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
13.0	52.0	GO:0004360	glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
6.0	18.0	GO:0005046	KDEL sequence binding(GO:0005046)
5.1	25.4	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
4.7	14.1	GO:0047757	chondroitin-glucuronate 5-epimerase activity(GO:0047757)
3.6	21.6	GO:0046923	ER retention sequence binding(GO:0046923)
2.0	6.0	GO:0031755	endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
1.9	13.0	GO:0048408	epidermal growth factor binding(GO:0048408)
1.4	13.9	GO:0070569	uridylyltransferase activity(GO:0070569)
1.3	4.0	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
1.2	15.9	GO:0048407	platelet-derived growth factor binding(GO:0048407)
1.1	12.6	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
1.0	5.9	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
1.0	2.9	GO:0051717	inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717)
0.9	5.5	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.9	29.5	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.8	11.0	GO:0070567	cytidylyltransferase activity(GO:0070567)
0.8	3.3	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.8	16.8	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.7	3.6	GO:0051998	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.7	16.5	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.7	5.7	GO:0102338	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.7	2.8	GO:0050211	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.7	2.0	GO:0031403	lithium ion binding(GO:0031403)
0.7	2.0	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.6	1.9	GO:0070704	C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
0.6	10.9	GO:0008179	adenylate cyclase binding(GO:0008179)
0.6	4.8	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.6	16.0	GO:0003746	translation elongation factor activity(GO:0003746)
0.6	8.2	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.6	5.2	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.6	2.3	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.5	6.8	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.5	11.6	GO:0008242	omega peptidase activity(GO:0008242)
0.5	14.2	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.5	9.4	GO:0070513	death domain binding(GO:0070513)
0.5	15.8	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.5	1.5	GO:0001226	RNA polymerase II transcription corepressor binding(GO:0001226)
0.5	1.9	GO:0034353	RNA pyrophosphohydrolase activity(GO:0034353)
0.4	9.4	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.4	18.6	GO:0003785	actin monomer binding(GO:0003785)
0.4	2.2	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.4	3.9	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.4	3.8	GO:0016875	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.4	6.9	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.3	3.6	GO:0046870	cadmium ion binding(GO:0046870)
0.3	10.5	GO:0001848	complement binding(GO:0001848)
0.3	2.1	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.3	1.6	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.3	1.8	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.2	1.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.2	7.0	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
0.2	6.1	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.2	1.5	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.2	13.3	GO:0003743	translation initiation factor activity(GO:0003743)
0.2	5.1	GO:0017166	vinculin binding(GO:0017166)
0.2	37.6	GO:0003735	structural constituent of ribosome(GO:0003735)
0.2	1.7	GO:0043142	single-stranded DNA-dependent ATPase activity(GO:0043142)
0.2	5.5	GO:0005246	calcium channel regulator activity(GO:0005246)
0.1	4.0	GO:0004029	aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1	2.7	GO:0031996	thioesterase binding(GO:0031996)
0.1	21.4	GO:0000149	SNARE binding(GO:0000149)
0.1	5.5	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.1	2.8	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	1.4	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.1	0.8	GO:0061133	endopeptidase activator activity(GO:0061133)
0.1	2.0	GO:0042809	vitamin D receptor binding(GO:0042809)
0.1	3.8	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.1	10.6	GO:0070491	repressing transcription factor binding(GO:0070491)
0.1	1.6	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.1	0.4	GO:0004995	tachykinin receptor activity(GO:0004995)
0.1	2.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.1	1.5	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.1	1.8	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	17.9	GO:0004721	phosphoprotein phosphatase activity(GO:0004721)
0.1	0.9	GO:0016423	tRNA (guanine) methyltransferase activity(GO:0016423)
0.1	1.7	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.1	1.0	GO:0005402	sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.1	0.8	GO:0045504	dynein heavy chain binding(GO:0045504)
0.1	3.8	GO:0097472	cyclin-dependent protein kinase activity(GO:0097472)
0.1	1.7	GO:0017025	TBP-class protein binding(GO:0017025)
0.1	1.5	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1	5.2	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.1	2.8	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.7	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	37.7	GO:0005509	calcium ion binding(GO:0005509)
0.0	0.6	GO:0043274	phospholipase binding(GO:0043274)
0.0	1.3	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	1.5	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	2.8	GO:0008565	protein transporter activity(GO:0008565)
0.0	17.9	GO:0005198	structural molecule activity(GO:0005198)
0.0	2.4	GO:0008276	protein methyltransferase activity(GO:0008276)
0.0	0.6	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	1.5	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	7.7	GO:0045296	cadherin binding(GO:0045296)
0.0	4.3	GO:0044822	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0	0.3	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.3	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	1.4	GO:0051219	phosphoprotein binding(GO:0051219)
0.0	20.1	GO:0003723	RNA binding(GO:0003723)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	22.8	PID ARF 3PATHWAY	Arf1 pathway
0.5	5.2	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.5	18.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.4	11.1	ST G ALPHA S PATHWAY	G alpha s Pathway
0.3	12.9	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.3	20.4	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.3	41.1	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.2	3.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2	16.5	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.2	10.3	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.2	3.8	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2	2.9	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2	8.9	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
0.2	1.3	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.1	4.0	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.1	25.7	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	2.3	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.1	17.2	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.1	5.3	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.1	2.7	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	1.8	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.1	2.7	PID FOXO PATHWAY	FoxO family signaling
0.1	1.5	ST GAQ PATHWAY	G alpha q Pathway
0.0	1.9	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.9	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.0	1.5	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	1.7	PID P73PATHWAY	p73 transcription factor network
0.0	1.6	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.7	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.7	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	16.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
1.0	8.0	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.9	14.5	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.8	16.5	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.7	10.4	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
0.6	45.4	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.6	11.1	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.6	10.6	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.5	9.4	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.5	11.2	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.4	78.2	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.4	16.8	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.3	5.2	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.3	41.7	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.3	6.6	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2	2.9	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.2	6.0	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.2	1.6	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.2	14.7	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.2	8.0	REACTOME TRANSLATION	Genes involved in Translation
0.2	4.0	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.2	5.7	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2	3.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.2	3.8	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.2	7.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.2	3.9	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1	3.8	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.1	1.9	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.1	1.8	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	2.0	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.1	1.7	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	4.1	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.1	2.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.1	1.4	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	1.5	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	1.9	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1	2.3	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1	0.9	REACTOME SIGNALING BY NOTCH3	Genes involved in Signaling by NOTCH3
0.1	1.7	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1	1.6	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.1	1.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	0.4	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1	10.8	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	1.5	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	2.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.0	2.3	REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT	Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0	3.3	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.7	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.8	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	4.1	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	2.7	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0	0.9	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.6	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.8	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase

Results for CREB3L1_CREB3

Z-value: 1.67

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Transcription factors associated with CREB3L1_CREB3

Activity-expression correlation:

Activity profile of CREB3L1_CREB3 motif

Sorted Z-values of CREB3L1_CREB3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB3L1_CREB3

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: