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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for CREB3L2

Z-value: 0.53

Motif logo

Transcription factors associated with CREB3L2

Gene Symbol Gene ID Gene Info
ENSG00000182158.15 CREB3L2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CREB3L2hg38_v1_chr7_-_138002017_1380021380.372.0e-08Click!

Activity profile of CREB3L2 motif

Sorted Z-values of CREB3L2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB3L2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr21_-_26843012 18.91 ENST00000517777.6
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr21_-_26843063 18.78 ENST00000678221.1
ADAM metallopeptidase with thrombospondin type 1 motif 1
chr8_+_22367259 17.47 ENST00000520644.1
ENST00000359741.10
ENST00000381237.6
ENST00000240095.10
solute carrier family 39 member 14
chr12_-_55728977 14.85 ENST00000552164.5
CD63 molecule
chr12_-_55729660 14.65 ENST00000546457.1
ENST00000549117.5
CD63 molecule
chr15_-_60397964 14.40 ENST00000558998.5
ENST00000560165.5
ENST00000557986.5
ENST00000559467.5
ENST00000677968.1
ENST00000678450.1
ENST00000332680.8
ENST00000396024.7
ENST00000557906.6
ENST00000558558.6
ENST00000559113.6
ENST00000559780.6
ENST00000559956.6
ENST00000560468.6
ENST00000678870.1
ENST00000678061.1
ENST00000451270.7
ENST00000421017.6
ENST00000560466.5
ENST00000558132.5
ENST00000559370.5
ENST00000559725.5
ENST00000558985.6
ENST00000679109.1
annexin A2
chr12_-_55728994 14.00 ENST00000257857.9
CD63 molecule
chr12_-_55728640 13.36 ENST00000551173.5
ENST00000420846.7
CD63 molecule
chr11_+_32091065 12.71 ENST00000054950.4
reticulocalbin 1
chr15_-_60398733 12.64 ENST00000559818.6
annexin A2
chr2_-_46915745 11.71 ENST00000649435.1
ENST00000409105.5
ENST00000319466.9
ENST00000409973.5
ENST00000409913.5
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chr7_-_6484057 11.69 ENST00000490996.1
ENST00000258739.9
ENST00000436575.5
KDEL endoplasmic reticulum protein retention receptor 2
diacylglycerol lipase beta
chr2_-_46916020 11.67 ENST00000409800.5
ENST00000409218.5
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chr8_+_97775775 11.07 ENST00000521545.7
lysosomal protein transmembrane 4 beta
chr3_-_123884290 10.95 ENST00000346322.9
ENST00000360772.7
ENST00000360304.8
myosin light chain kinase
chr2_+_46699241 10.24 ENST00000394861.3
suppressor of cytokine signaling 5
chr17_-_15260752 9.57 ENST00000676329.1
ENST00000675551.1
ENST00000644020.1
ENST00000674947.1
peripheral myelin protein 22
chr3_+_123067016 9.09 ENST00000316218.12
protein disulfide isomerase family A member 5
chr6_+_151240368 8.92 ENST00000253332.5
A-kinase anchoring protein 12
chr6_+_151239951 8.64 ENST00000402676.7
A-kinase anchoring protein 12
chr3_-_57597443 8.27 ENST00000463880.1
ADP ribosylation factor 4
chr2_-_69387188 8.02 ENST00000674507.1
ENST00000357308.9
glutamine--fructose-6-phosphate transaminase 1
chr2_-_69387241 7.44 ENST00000361060.5
glutamine--fructose-6-phosphate transaminase 1
chr10_-_125161019 7.38 ENST00000411419.6
C-terminal binding protein 2
chr2_-_69387130 6.91 ENST00000674438.1
glutamine--fructose-6-phosphate transaminase 1
chr6_-_7910776 6.70 ENST00000379757.9
thioredoxin domain containing 5
chr18_+_9708230 6.65 ENST00000578921.6
RAB31, member RAS oncogene family
chr12_-_48924919 6.61 ENST00000444214.6
FKBP prolyl isomerase 11
chr5_+_138753412 6.52 ENST00000520339.5
ENST00000627109.2
ENST00000302763.12
ENST00000518910.5
catenin alpha 1
chr5_-_144170607 6.46 ENST00000448443.6
ENST00000513112.5
ENST00000519064.5
ENST00000274496.10
ENST00000522203.5
Yip1 domain family member 5
chr17_+_41812974 6.44 ENST00000321562.9
FKBP prolyl isomerase 10
chr17_+_19648792 6.38 ENST00000630662.2
aldehyde dehydrogenase 3 family member A2
chr6_-_144008364 6.23 ENST00000625622.2
PLAG1 like zinc finger 1
chr17_-_41812586 6.00 ENST00000355468.7
ENST00000590496.1
prolyl 3-hydroxylase family member 4 (inactive)
chr7_-_121396284 6.00 ENST00000359943.8
ENST00000426156.1
ENST00000412653.5
FAM3 metabolism regulating signaling molecule C
chr6_-_144008118 5.99 ENST00000629195.2
ENST00000650125.1
ENST00000647880.1
ENST00000649307.1
ENST00000674357.1
ENST00000417959.4
ENST00000635591.1
PLAG1 like zinc finger 1
hydatidiform mole associated and imprinted
chrX_+_106693838 5.84 ENST00000324342.7
ring finger protein 128
chr6_-_144008396 5.53 ENST00000354765.6
ENST00000416623.5
ENST00000649211.1
PLAG1 like zinc finger 1
chr11_-_6481350 5.38 ENST00000423813.6
ENST00000614314.4
ADP ribosylation factor interacting protein 2
chr2_+_197500398 5.33 ENST00000604458.1
HSPE1-MOB4 readthrough
chr3_-_57597325 5.28 ENST00000496292.5
ENST00000489843.1
ENST00000303436.11
ADP ribosylation factor 4
chr4_+_187995764 5.25 ENST00000509524.5
ENST00000326866.5
ZFP42 zinc finger protein
chr8_+_38030496 5.13 ENST00000338825.5
eukaryotic translation initiation factor 4E binding protein 1
chr17_+_19648723 5.02 ENST00000672357.1
ENST00000584332.6
ENST00000176643.11
ENST00000339618.8
ENST00000579855.5
ENST00000671878.1
ENST00000395575.7
aldehyde dehydrogenase 3 family member A2
chr2_+_46698909 4.99 ENST00000650611.1
ENST00000306503.5
long intergenic non-protein coding RNA 1118
suppressor of cytokine signaling 5
chr7_+_16753731 4.90 ENST00000262067.5
tetraspanin 13
chr17_+_19648915 4.90 ENST00000672567.1
ENST00000672709.1
aldehyde dehydrogenase 3 family member A2
chr11_-_6481304 4.87 ENST00000254584.6
ENST00000525235.1
ENST00000396777.8
ENST00000445086.6
ADP ribosylation factor interacting protein 2
chr14_+_61695435 4.86 ENST00000337138.9
ENST00000394997.5
hypoxia inducible factor 1 subunit alpha
chr21_-_17612842 4.86 ENST00000339775.10
ENST00000348354.7
BTG anti-proliferation factor 3
chrX_-_103686687 4.82 ENST00000441076.7
ENST00000422355.5
ENST00000442614.5
ENST00000451301.5
mortality factor 4 like 2
chr2_-_65130090 4.78 ENST00000398529.7
ENST00000409751.1
ENST00000409892.5
ENST00000409784.8
RAB1A, member RAS oncogene family
chr17_+_51166431 4.67 ENST00000393190.4
NME/NM23 nucleoside diphosphate kinase 2
chr1_-_112956063 4.41 ENST00000538576.5
ENST00000369626.8
ENST00000458229.6
solute carrier family 16 member 1
chr3_-_179071742 4.37 ENST00000311417.7
ENST00000652290.1
zinc finger matrin-type 3
chr3_+_141426108 4.34 ENST00000441582.2
ENST00000510726.1
zinc finger and BTB domain containing 38
chr8_+_81280527 4.31 ENST00000297258.11
fatty acid binding protein 5
chr20_+_25248036 4.09 ENST00000216962.9
glycogen phosphorylase B
chr2_+_171687672 4.07 ENST00000409197.5
ENST00000456808.5
ENST00000409317.5
ENST00000409773.5
ENST00000411953.5
ENST00000409453.5
dynein cytoplasmic 1 intermediate chain 2
chr9_+_706841 4.03 ENST00000382293.7
KN motif and ankyrin repeat domains 1
chr2_+_171687457 3.96 ENST00000397119.8
ENST00000410079.7
ENST00000438879.5
dynein cytoplasmic 1 intermediate chain 2
chr2_-_27323006 3.78 ENST00000402310.5
ENST00000405983.5
ENST00000403262.6
mitochondrial inner membrane protein MPV17
chr21_-_43076362 3.77 ENST00000359624.7
ENST00000352178.9
cystathionine beta-synthase
chr19_-_46787278 3.71 ENST00000412532.6
solute carrier family 1 member 5
chr2_+_216633411 3.65 ENST00000233809.9
insulin like growth factor binding protein 2
chr2_+_171687409 3.55 ENST00000452242.5
ENST00000340296.8
dynein cytoplasmic 1 intermediate chain 2
chr5_+_134648772 3.48 ENST00000398844.7
ENST00000322887.8
SEC24 homolog A, COPII coat complex component
chr21_-_6468040 3.45 ENST00000618024.4
ENST00000617706.4
cystathionine beta-synthase like
chr7_-_134459089 3.44 ENST00000285930.9
aldo-keto reductase family 1 member B
chr19_-_4670331 3.42 ENST00000262947.8
ENST00000599630.1
myeloid derived growth factor
chr21_-_43075831 3.39 ENST00000398158.5
ENST00000398165.8
cystathionine beta-synthase
chr4_-_18021727 3.37 ENST00000675605.1
ENST00000675927.1
ENST00000674942.1
ENST00000675143.1
ENST00000382226.5
ENST00000326877.8
ENST00000635767.1
ligand dependent nuclear receptor corepressor like
chr2_+_74198605 3.34 ENST00000409804.5
ENST00000678340.1
ENST00000679055.1
ENST00000394053.7
ENST00000409601.1
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr20_+_45891309 3.27 ENST00000354880.9
ENST00000646241.3
ENST00000191018.9
cathepsin A
chr8_+_1823918 3.18 ENST00000349830.8
Rho guanine nucleotide exchange factor 10
chr13_+_113297217 3.13 ENST00000332556.5
lysosomal associated membrane protein 1
chr21_-_6467509 3.07 ENST00000624406.3
ENST00000398168.5
ENST00000624934.3
cystathionine beta-synthase like
chr8_+_22245125 3.02 ENST00000306433.9
ENST00000519237.5
ENST00000397802.8
RNA polymerase III subunit D
chr20_+_45891370 2.99 ENST00000607482.6
ENST00000372459.7
cathepsin A
chr17_-_38853629 2.98 ENST00000378096.3
ENST00000479035.7
ENST00000394332.5
ENST00000394333.5
ENST00000577407.5
ribosomal protein L23
chr2_+_197500371 2.97 ENST00000409468.1
ENST00000233893.10
heat shock protein family E (Hsp10) member 1
chr17_+_42536226 2.95 ENST00000225927.7
N-acetyl-alpha-glucosaminidase
chr11_-_113875555 2.95 ENST00000003302.8
ENST00000545540.5
ubiquitin specific peptidase 28
chr22_-_42857194 2.90 ENST00000437119.6
ENST00000454099.5
ENST00000263245.10
ADP ribosylation factor GTPase activating protein 3
chr16_+_283157 2.86 ENST00000219406.11
ENST00000404312.5
ENST00000456379.1
protein disulfide isomerase family A member 2
chr11_+_68008542 2.84 ENST00000614849.4
aldehyde dehydrogenase 3 family member B1
chr1_-_11805977 2.81 ENST00000376486.3
methylenetetrahydrofolate reductase
chr17_+_42536510 2.79 ENST00000585572.1
ENST00000586516.5
ENST00000591587.1
novel transcript
N-acetyl-alpha-glucosaminidase
chr2_+_171687501 2.77 ENST00000508530.5
dynein cytoplasmic 1 intermediate chain 2
chr1_-_11805924 2.74 ENST00000418034.1
methylenetetrahydrofolate reductase
chr1_-_11805949 2.74 ENST00000376590.9
methylenetetrahydrofolate reductase
chr14_+_74084947 2.72 ENST00000674221.1
ENST00000554938.2
lin-52 DREAM MuvB core complex component
chr12_+_6724008 2.68 ENST00000626119.2
ENST00000543155.6
COP9 signalosome subunit 7A
chr11_-_64246907 2.67 ENST00000309318.8
protein phosphatase 1 regulatory inhibitor subunit 14B
chr2_-_27119012 2.65 ENST00000312734.8
cell growth regulator with EF-hand domain 1
chr2_-_120223371 2.61 ENST00000426077.3
transmembrane protein 185B
chr1_-_1232031 2.60 ENST00000263741.12
stromal cell derived factor 4
chr19_+_48954850 2.60 ENST00000345358.12
ENST00000539787.2
ENST00000415969.6
ENST00000354470.7
ENST00000506183.5
ENST00000391871.4
ENST00000293288.12
BCL2 associated X, apoptosis regulator
chr3_+_129249594 2.58 ENST00000314797.10
COPI coat complex subunit gamma 1
chr3_-_155854375 2.57 ENST00000643144.2
ENST00000359479.7
ENST00000646424.1
solute carrier family 33 member 1
chr2_-_27119099 2.53 ENST00000402550.5
ENST00000402394.6
cell growth regulator with EF-hand domain 1
chr5_-_131797030 2.52 ENST00000615660.4
folliculin interacting protein 1
chr1_-_1232061 2.49 ENST00000660930.1
stromal cell derived factor 4
chr1_-_1231966 2.48 ENST00000360001.12
stromal cell derived factor 4
chr21_+_36069941 2.47 ENST00000530908.5
ENST00000439427.2
ENST00000290349.11
ENST00000399191.3
carbonyl reductase 1
chr18_-_49460630 2.43 ENST00000675505.1
ENST00000442713.6
ENST00000269445.10
dymeclin
chr12_+_6724071 2.42 ENST00000229251.7
ENST00000539735.5
ENST00000538410.5
COP9 signalosome subunit 7A
chr17_-_76726753 2.40 ENST00000617192.4
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
chr16_+_66880503 2.35 ENST00000568869.1
ENST00000311765.4
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr1_-_77683356 2.33 ENST00000414381.5
ENST00000370798.5
zinc finger ZZ-type containing 3
chr19_+_36214602 2.32 ENST00000456324.5
zinc finger protein 146
chr2_+_200812185 2.30 ENST00000409226.5
ENST00000452790.6
basic leucine zipper and W2 domains 1
chr19_+_36215096 2.28 ENST00000443387.3
zinc finger protein 146
chr1_-_68497030 2.22 ENST00000456315.7
ENST00000525124.1
ENST00000370966.9
DEP domain containing 1
chr12_+_57230301 2.20 ENST00000553474.5
serine hydroxymethyltransferase 2
chr8_-_132105265 2.16 ENST00000414222.1
HERV-H LTR-associating 1
chr17_-_7234262 2.13 ENST00000575756.5
ENST00000575458.5
dishevelled segment polarity protein 2
chr1_+_116373233 2.11 ENST00000295598.10
ATPase Na+/K+ transporting subunit alpha 1
chr20_+_62642492 2.09 ENST00000217159.6
solute carrier organic anion transporter family member 4A1
chr2_-_27118900 2.06 ENST00000405600.5
ENST00000260595.9
cell growth regulator with EF-hand domain 1
chr12_+_57230086 2.02 ENST00000414700.7
ENST00000557703.5
serine hydroxymethyltransferase 2
chr17_-_76726590 2.00 ENST00000397625.9
ENST00000445478.6
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
chrX_+_48574938 1.99 ENST00000376755.1
RNA binding motif protein 3
chr2_-_73112885 1.97 ENST00000486777.7
RAB11 family interacting protein 5
chr5_-_131796921 1.96 ENST00000307968.11
ENST00000307954.12
folliculin interacting protein 1
chr12_+_6724271 1.94 ENST00000534947.5
ENST00000541866.5
ENST00000534877.5
ENST00000538753.5
COP9 signalosome subunit 7A
chr17_-_76726453 1.82 ENST00000585429.1
jumonji domain containing 6, arginine demethylase and lysine hydroxylase
chr17_-_18363451 1.81 ENST00000354098.7
serine hydroxymethyltransferase 1
chr17_+_74432079 1.81 ENST00000392627.7
ENST00000392628.7
ENST00000582473.2
G protein-coupled receptor class C group 5 member C
chr6_+_159969070 1.77 ENST00000356956.6
insulin like growth factor 2 receptor
chr12_-_122266425 1.76 ENST00000643696.1
ENST00000267199.9
VPS33A core subunit of CORVET and HOPS complexes
chr22_-_43015133 1.74 ENST00000453643.5
ENST00000263246.8
protein kinase C and casein kinase substrate in neurons 2
chr17_-_18363504 1.70 ENST00000583780.1
ENST00000316694.8
ENST00000352886.10
serine hydroxymethyltransferase 1
chr10_-_70170466 1.69 ENST00000373239.2
ENST00000373241.9
ENST00000373242.6
secretion associated Ras related GTPase 1A
chr1_-_77682639 1.68 ENST00000370801.8
ENST00000433749.5
zinc finger ZZ-type containing 3
chr17_-_81937221 1.64 ENST00000402252.6
ENST00000583564.5
ENST00000585244.1
ENST00000337943.9
ENST00000579698.5
pyrroline-5-carboxylate reductase 1
chr22_-_29267965 1.58 ENST00000216085.12
rhomboid domain containing 3
chrX_+_48574477 1.58 ENST00000376759.8
RNA binding motif protein 3
chr5_-_115544734 1.55 ENST00000274457.5
fem-1 homolog C
chr9_-_127715633 1.54 ENST00000335223.5
ENST00000416214.1
ENST00000543175.5
peptidyl-tRNA hydrolase 1 homolog
chr17_-_81937320 1.51 ENST00000577624.5
ENST00000403172.8
ENST00000619204.4
ENST00000629768.2
pyrroline-5-carboxylate reductase 1
chr17_-_81937277 1.50 ENST00000405481.8
ENST00000329875.13
ENST00000585215.5
pyrroline-5-carboxylate reductase 1
chr8_+_98117285 1.49 ENST00000401707.7
ENST00000522319.5
POP1 homolog, ribonuclease P/MRP subunit
chr2_+_64454145 1.48 ENST00000238875.10
galectin like
chrX_-_120560884 1.45 ENST00000404115.8
cullin 4B
chrX_-_120561424 1.45 ENST00000681206.1
ENST00000679927.1
ENST00000336592.11
cullin 4B
chr12_+_57229694 1.43 ENST00000557487.5
ENST00000328923.8
ENST00000555634.5
ENST00000556689.5
serine hydroxymethyltransferase 2
chr15_+_58431985 1.40 ENST00000433326.2
ENST00000299022.10
lipase C, hepatic type
chr21_+_7744971 1.37 ENST00000622934.3
ENST00000619874.4
ENST00000612624.4
ENST00000624304.3
ENST00000624758.3
small integral membrane protein 11B
chr10_-_102714371 1.35 ENST00000260746.6
ADP ribosylation factor like GTPase 3
chr22_-_36507022 1.35 ENST00000216187.10
ENST00000397224.9
ENST00000423980.1
FAD dependent oxidoreductase domain containing 2
chr11_+_6481473 1.34 ENST00000530751.1
ENST00000254616.11
translocase of inner mitochondrial membrane 10B
chr2_+_200811882 1.34 ENST00000409600.6
basic leucine zipper and W2 domains 1
chr5_-_151157722 1.31 ENST00000517486.5
ENST00000377751.9
ENST00000521512.5
ENST00000517757.5
ENST00000354546.10
annexin A6
chrY_-_21894439 1.28 ENST00000418956.2
ENST00000382680.5
RNA binding motif protein Y-linked family 1 member D
chr1_-_33431079 1.26 ENST00000683057.1
polyhomeotic homolog 2
chr11_-_61792581 1.26 ENST00000537328.6
transmembrane protein 258
chr19_+_13764502 1.24 ENST00000040663.8
ENST00000319545.12
methylthioribose-1-phosphate isomerase 1
chr1_-_243851066 1.19 ENST00000263826.12
AKT serine/threonine kinase 3
chrX_-_15854743 1.18 ENST00000450644.2
adaptor related protein complex 1 subunit sigma 2
chr1_+_42456525 1.16 ENST00000372560.3
ENST00000372561.4
ENST00000372556.3
phosphopantothenoylcysteine synthetase
chr12_+_57230336 1.16 ENST00000555773.5
ENST00000554975.5
ENST00000449049.7
serine hydroxymethyltransferase 2
chr16_+_1678271 1.14 ENST00000562684.5
ENST00000561516.5
ENST00000248098.8
ENST00000382711.9
ENST00000566742.5
Jupiter microtubule associated homolog 2
chr12_+_120978686 1.14 ENST00000541395.5
ENST00000544413.2
HNF1 homeobox A
chr8_+_1823967 1.12 ENST00000520359.5
ENST00000518288.5
Rho guanine nucleotide exchange factor 10
chr15_+_58771280 1.11 ENST00000559228.6
ENST00000450403.3
MINDY lysine 48 deubiquitinase 2
chr19_+_33194308 1.05 ENST00000253193.9
LDL receptor related protein 3
chr8_-_143597362 1.03 ENST00000534380.6
ENST00000533494.6
ENST00000531218.6
ENST00000317198.10
ENST00000526340.5
ENST00000419152.7
ENST00000532400.1
ENST00000529516.6
ENST00000534377.6
ENST00000531621.5
ENST00000530191.6
ENST00000524900.1
ENST00000526838.5
ENST00000531931.1
ENST00000534475.5
ENST00000423316.7
ENST00000442189.6
ENST00000524624.5
ENST00000532596.5
ENST00000529832.5
ENST00000530306.5
ENST00000530545.5
ENST00000525261.5
ENST00000534804.5
ENST00000528303.5
ENST00000528610.5
ENST00000526710.1
eukaryotic translation elongation factor 1 delta
chrX_+_154458274 1.02 ENST00000369682.4
plexin A3
chr2_-_73113018 0.98 ENST00000258098.6
RAB11 family interacting protein 5
chr19_-_42255119 0.96 ENST00000222329.9
ENST00000594664.1
ETS2 repressor factor
novel protein
chr16_+_1678304 0.96 ENST00000569765.5
Jupiter microtubule associated homolog 2
chr1_+_43979877 0.94 ENST00000356836.10
ENST00000309519.8
beta-1,4-galactosyltransferase 2
chrX_-_120560947 0.91 ENST00000674137.11
ENST00000371322.11
ENST00000681090.1
cullin 4B
chr17_-_42181116 0.90 ENST00000264661.4
potassium voltage-gated channel subfamily H member 4
chr20_-_63537361 0.89 ENST00000217185.3
ENST00000542869.3
protein tyrosine kinase 6
chr19_-_2783308 0.88 ENST00000677562.1
ENST00000677754.1
small glutamine rich tetratricopeptide repeat containing alpha
chr2_-_148020689 0.87 ENST00000457954.5
ENST00000392857.10
ENST00000540442.5
ENST00000535373.5
origin recognition complex subunit 4
chr6_-_84227634 0.87 ENST00000617909.1
ENST00000403245.8
centrosomal protein 162
chr15_-_72375940 0.85 ENST00000567213.2
ENST00000566304.5
ENST00000567159.5
ENST00000683884.1
ENST00000684520.1
ENST00000268097.10
hexosaminidase subunit alpha
chr4_+_37453914 0.84 ENST00000381980.9
ENST00000508175.5
chromosome 4 open reading frame 19
chr13_+_34942263 0.81 ENST00000379939.7
ENST00000400445.7
neurobeachin
chr1_+_42456090 0.79 ENST00000372562.1
phosphopantothenoylcysteine synthetase
chrY_-_21918032 0.78 ENST00000382658.5
ENST00000382659.6
RNA binding motif protein Y-linked family 1 member E
chr13_+_32315071 0.78 ENST00000544455.6
BRCA2 DNA repair associated
chr7_-_142885737 0.69 ENST00000359396.9
ENST00000436401.1
transient receptor potential cation channel subfamily V member 6
chr10_+_102132994 0.69 ENST00000413464.6
ENST00000278070.7
PPARG related coactivator 1
chr6_-_84227596 0.69 ENST00000257766.8
centrosomal protein 162
chr1_-_109619605 0.68 ENST00000679935.1
G protein subunit alpha transducin 2
chr2_-_88627365 0.67 ENST00000303236.9
eukaryotic translation initiation factor 2 alpha kinase 3
chr19_+_1275997 0.65 ENST00000469144.5
family with sequence similarity 174 member C
chr17_-_42181081 0.63 ENST00000607371.5
potassium voltage-gated channel subfamily H member 4
chrY_+_21511338 0.62 ENST00000383020.7
ENST00000619219.1
ENST00000439108.6
ENST00000303902.9
RNA binding motif protein Y-linked family 1 member B
RNA binding motif protein Y-linked family 1 member A1
chr12_+_49961864 0.61 ENST00000293599.7
aquaporin 5
chrY_+_21534879 0.61 ENST00000382707.6
RNA binding motif protein Y-linked family 1 member A1
chr19_+_49677228 0.60 ENST00000454376.7
ENST00000524771.5
protein arginine methyltransferase 1
chr2_+_64453969 0.58 ENST00000464281.5
galectin like
chr7_+_151232464 0.57 ENST00000482173.5
ENST00000495645.5
ENST00000035307.6
chondroitin polymerizing factor 2
chr2_+_206159580 0.56 ENST00000236957.9
ENST00000392221.5
ENST00000445505.5
eukaryotic translation elongation factor 1 beta 2
chr15_-_50686768 0.55 ENST00000560955.5
ENST00000646667.1
transient receptor potential cation channel subfamily M member 7

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.4 27.0 GO:0044111 development involved in symbiotic interaction(GO:0044111)
4.1 16.3 GO:0033306 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
4.1 56.9 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
2.7 13.7 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
2.5 7.6 GO:0070625 zymogen granule exocytosis(GO:0070625)
2.4 14.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
2.2 6.5 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
2.1 6.2 GO:0070078 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine(GO:0018395) histone arginine demethylation(GO:0070077) histone H3-R2 demethylation(GO:0070078) histone H4-R3 demethylation(GO:0070079)
2.0 36.1 GO:0001542 ovulation from ovarian follicle(GO:0001542)
1.9 17.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
1.8 11.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
1.7 10.3 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
1.6 14.4 GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
1.5 17.6 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
1.5 14.5 GO:0006621 protein retention in ER lumen(GO:0006621)
1.4 8.3 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
1.4 12.4 GO:0031584 activation of phospholipase D activity(GO:0031584)
1.3 5.1 GO:1990928 response to amino acid starvation(GO:1990928)
1.2 22.4 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
1.2 4.7 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
1.1 3.4 GO:0006059 hexitol metabolic process(GO:0006059)
1.0 3.1 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
1.0 4.0 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.9 3.7 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.9 2.6 GO:1902512 B cell selection(GO:0002339) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.8 4.9 GO:0070101 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030) positive regulation of chemokine-mediated signaling pathway(GO:0070101)
0.7 3.0 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.7 7.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.6 2.6 GO:0051182 coenzyme transport(GO:0051182)
0.6 4.4 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.6 6.3 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.6 1.9 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.6 9.9 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.6 5.8 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.5 6.5 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.5 4.3 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.5 9.6 GO:0032060 bleb assembly(GO:0032060)
0.5 10.3 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.5 7.0 GO:0000338 protein deneddylation(GO:0000338)
0.4 23.4 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.4 5.7 GO:0046548 locomotor rhythm(GO:0045475) retinal rod cell development(GO:0046548)
0.4 3.0 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.4 1.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.4 6.0 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.3 1.5 GO:0016078 tRNA catabolic process(GO:0016078)
0.3 1.6 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.3 0.8 GO:0035565 regulation of pronephros size(GO:0035565)
0.3 3.8 GO:0032836 glomerular basement membrane development(GO:0032836)
0.2 13.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.2 1.2 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.2 2.1 GO:0090032 negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.2 1.7 GO:0070836 caveola assembly(GO:0070836)
0.2 3.8 GO:0070914 UV-damage excision repair(GO:0070914)
0.2 1.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.2 2.5 GO:0042373 vitamin K metabolic process(GO:0042373)
0.2 1.5 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.2 18.3 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.2 0.5 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.2 4.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 2.1 GO:0046185 aldehyde catabolic process(GO:0046185)
0.2 15.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.2 0.7 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.2 3.4 GO:0046655 folic acid metabolic process(GO:0046655)
0.2 0.6 GO:0015670 carbon dioxide transport(GO:0015670)
0.1 1.8 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.1 2.6 GO:0051683 establishment of Golgi localization(GO:0051683)
0.1 2.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.1 6.7 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 3.0 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 1.0 GO:1902287 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.1 4.3 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.1 3.7 GO:0010226 response to lithium ion(GO:0010226)
0.1 5.6 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 0.7 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.1 3.2 GO:0005980 glycogen catabolic process(GO:0005980)
0.1 0.3 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1 0.5 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.1 1.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 7.3 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 0.4 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.2 GO:0046066 dGDP metabolic process(GO:0046066)
0.1 3.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 2.1 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 1.5 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 0.9 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.9 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.9 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 5.2 GO:0008585 female gonad development(GO:0008585)
0.0 1.3 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 1.3 GO:0042461 photoreceptor cell development(GO:0042461)
0.0 0.3 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 3.4 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 0.5 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.2 GO:0045007 depurination(GO:0045007)
0.0 0.2 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 10.9 GO:0043010 camera-type eye development(GO:0043010)
0.0 0.3 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 4.9 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 1.2 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 1.3 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.9 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.9 GO:0006270 DNA replication initiation(GO:0006270)
0.0 1.8 GO:0032526 response to retinoic acid(GO:0032526)
0.0 2.8 GO:0002576 platelet degranulation(GO:0002576)
0.0 2.4 GO:0060348 bone development(GO:0060348)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.4 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 56.9 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
3.9 27.0 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.9 2.7 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.8 6.3 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.7 3.4 GO:0097454 Schwann cell microvillus(GO:0097454)
0.7 6.8 GO:0070552 BRISC complex(GO:0070552)
0.6 14.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.5 7.6 GO:0032059 bleb(GO:0032059)
0.5 6.5 GO:0005915 zonula adherens(GO:0005915)
0.5 7.4 GO:0097470 ribbon synapse(GO:0097470)
0.4 1.2 GO:0033593 BRCA2-MAGE-D1 complex(GO:0033593)
0.4 9.6 GO:0043218 compact myelin(GO:0043218)
0.3 3.1 GO:0032010 phagolysosome(GO:0032010) alveolar lamellar body(GO:0097208)
0.3 3.8 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.3 25.4 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.3 6.0 GO:0031089 platelet dense granule lumen(GO:0031089)
0.3 6.5 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.3 1.8 GO:0071439 clathrin complex(GO:0071439)
0.3 36.5 GO:0005604 basement membrane(GO:0005604)
0.3 1.6 GO:0005879 axonemal microtubule(GO:0005879)
0.2 1.5 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.2 19.9 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 2.6 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 2.6 GO:0030126 COPI vesicle coat(GO:0030126)
0.2 4.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 2.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 14.2 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.2 11.0 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.2 4.8 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.2 0.5 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.2 6.0 GO:0000795 synaptonemal complex(GO:0000795)
0.1 8.9 GO:0005801 cis-Golgi network(GO:0005801)
0.1 7.0 GO:0008180 COP9 signalosome(GO:0008180)
0.1 3.0 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 19.3 GO:0032587 ruffle membrane(GO:0032587)
0.1 2.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.1 14.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.1 1.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 32.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 1.0 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 4.9 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.9 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 1.3 GO:0035102 PRC1 complex(GO:0035102)
0.1 18.5 GO:0030027 lamellipodium(GO:0030027)
0.1 0.3 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 8.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 3.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.1 0.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 1.3 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 6.5 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 1.9 GO:0016235 aggresome(GO:0016235)
0.0 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 8.9 GO:0005938 cell cortex(GO:0005938)
0.0 2.7 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 3.0 GO:0072562 blood microparticle(GO:0072562)
0.0 1.1 GO:0005905 clathrin-coated pit(GO:0005905)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.6 22.4 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
5.4 16.3 GO:0046577 long-chain-alcohol oxidase activity(GO:0046577)
5.4 27.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
3.9 11.7 GO:0005046 KDEL sequence binding(GO:0005046)
2.9 17.5 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
2.7 11.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
2.7 13.7 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
2.1 6.2 GO:0033749 histone demethylase activity (H3-R2 specific)(GO:0033746) histone demethylase activity (H4-R3 specific)(GO:0033749)
1.7 10.3 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
1.4 8.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
1.1 7.4 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
1.0 14.4 GO:0045504 dynein heavy chain binding(GO:0045504)
1.0 4.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
1.0 17.6 GO:0008179 adenylate cyclase binding(GO:0008179)
0.8 3.3 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.8 6.3 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.8 18.7 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.7 4.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.6 3.0 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.6 1.8 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.6 2.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.6 6.2 GO:0004673 protein histidine kinase activity(GO:0004673)
0.5 2.5 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.5 13.0 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.5 28.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.5 10.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.5 3.7 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.4 4.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.3 3.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.3 6.6 GO:0015929 hexosaminidase activity(GO:0015929)
0.3 1.5 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.3 2.7 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.3 35.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 5.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.3 2.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.2 6.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 2.8 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.2 4.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 0.9 GO:0004461 lactose synthase activity(GO:0004461)
0.2 2.6 GO:0051434 BH3 domain binding(GO:0051434)
0.2 0.6 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.2 1.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.2 1.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.2 2.1 GO:1990239 sodium:potassium-exchanging ATPase activity(GO:0005391) steroid hormone binding(GO:1990239)
0.1 3.0 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 0.7 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.1 1.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 1.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 2.6 GO:0015295 solute:proton symporter activity(GO:0015295)
0.1 4.9 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 2.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 3.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.3 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 5.0 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 0.4 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 2.0 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 6.3 GO:0019003 GDP binding(GO:0019003)
0.1 4.3 GO:0019894 kinesin binding(GO:0019894)
0.1 0.4 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.1 0.2 GO:0004766 spermidine synthase activity(GO:0004766)
0.1 4.6 GO:0005504 fatty acid binding(GO:0005504)
0.1 1.7 GO:0070300 phosphatidic acid binding(GO:0070300)
0.1 1.4 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.3 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 1.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.7 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 1.9 GO:0005109 frizzled binding(GO:0005109)
0.0 41.9 GO:0005509 calcium ion binding(GO:0005509)
0.0 2.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 4.4 GO:0002039 p53 binding(GO:0002039)
0.0 2.9 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.6 GO:0015250 water channel activity(GO:0015250)
0.0 3.7 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 2.6 GO:0051087 chaperone binding(GO:0051087)
0.0 2.9 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 6.0 GO:0005125 cytokine activity(GO:0005125)
0.0 4.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.0 2.5 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 10.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 1.3 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 0.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.2 GO:0005262 calcium channel activity(GO:0005262)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 10.3 PID ARF 3PATHWAY Arf1 pathway
0.3 18.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 11.0 PID AURORA B PATHWAY Aurora B signaling
0.2 4.9 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.2 41.3 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 26.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 15.2 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 9.6 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 1.2 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.1 5.1 PID INSULIN PATHWAY Insulin Pathway
0.1 5.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 9.3 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 2.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 4.8 PID PLK1 PATHWAY PLK1 signaling events
0.1 9.9 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 1.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 3.0 PID P53 REGULATION PATHWAY p53 pathway
0.0 2.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 3.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.8 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.5 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 2.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 24.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.3 53.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.3 5.1 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.3 4.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.3 11.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.3 8.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 11.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 4.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 20.6 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.2 7.9 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 13.3 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 6.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.2 4.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.2 3.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 3.0 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.1 4.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 2.4 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 4.9 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 2.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 2.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 3.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.1 1.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 0.9 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 2.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 4.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 0.9 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 1.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 1.0 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.8 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 2.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.7 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 3.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.7 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 1.4 REACTOME TRANSLATION Genes involved in Translation
0.0 0.8 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.5 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway