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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for CUUUGGU
Z-value: 0.51
Motif logo
miRNA associated with seed CUUUGGU
| Name | miRBASE accession |
|---|---|
|
hsa-miR-9-5p
|
MIMAT0000441 |
Activity profile of CUUUGGU motif
Sorted Z-values of CUUUGGU motif
Network of associatons between targets according to the STRING database.
First level regulatory network of CUUUGGU
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.5 | 22.4 | GO:0044111 | development involved in symbiotic interaction(GO:0044111) |
| 4.4 | 13.2 | GO:0060279 | regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279) |
| 4.1 | 12.4 | GO:0060434 | bronchus morphogenesis(GO:0060434) |
| 4.1 | 12.4 | GO:0051295 | establishment of meiotic spindle localization(GO:0051295) |
| 3.1 | 21.9 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 3.1 | 18.6 | GO:1903553 | positive regulation of extracellular exosome assembly(GO:1903553) |
| 3.0 | 17.7 | GO:0060978 | angiogenesis involved in coronary vascular morphogenesis(GO:0060978) |
| 2.9 | 14.6 | GO:0032792 | negative regulation of triglyceride biosynthetic process(GO:0010868) negative regulation of CREB transcription factor activity(GO:0032792) |
| 2.4 | 7.2 | GO:0090402 | oncogene-induced cell senescence(GO:0090402) |
| 2.4 | 7.1 | GO:0006447 | regulation of translational initiation by iron(GO:0006447) |
| 2.4 | 18.9 | GO:1902219 | negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219) |
| 2.4 | 9.4 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 2.2 | 13.2 | GO:0008218 | bioluminescence(GO:0008218) |
| 2.0 | 5.9 | GO:0021555 | midbrain-hindbrain boundary morphogenesis(GO:0021555) trochlear nerve development(GO:0021558) |
| 1.9 | 5.7 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
| 1.9 | 7.5 | GO:0018231 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 1.9 | 7.5 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 1.8 | 5.3 | GO:0043321 | regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323) |
| 1.6 | 6.5 | GO:1902617 | response to fluoride(GO:1902617) |
| 1.6 | 4.7 | GO:2000797 | amniotic stem cell differentiation(GO:0097086) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798) |
| 1.6 | 4.7 | GO:0097069 | response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387) |
| 1.5 | 4.6 | GO:1903778 | protein localization to vacuolar membrane(GO:1903778) |
| 1.5 | 3.0 | GO:0048808 | male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598) |
| 1.5 | 6.0 | GO:0042663 | regulation of endodermal cell fate specification(GO:0042663) |
| 1.5 | 20.9 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 1.5 | 5.9 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 1.4 | 7.2 | GO:0034036 | purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428) |
| 1.4 | 7.2 | GO:1901526 | positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925) |
| 1.4 | 9.5 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
| 1.4 | 4.1 | GO:0034402 | recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402) |
| 1.3 | 4.0 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 1.3 | 26.2 | GO:0043568 | positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568) |
| 1.3 | 6.5 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 1.2 | 7.5 | GO:0060414 | aorta smooth muscle tissue morphogenesis(GO:0060414) |
| 1.2 | 3.7 | GO:0001544 | initiation of primordial ovarian follicle growth(GO:0001544) |
| 1.2 | 4.7 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
| 1.2 | 4.7 | GO:0032058 | positive regulation of translational initiation in response to stress(GO:0032058) |
| 1.2 | 4.6 | GO:0045053 | protein retention in Golgi apparatus(GO:0045053) asymmetric Golgi ribbon formation(GO:0090164) |
| 1.1 | 27.0 | GO:0030208 | dermatan sulfate biosynthetic process(GO:0030208) |
| 1.1 | 8.8 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 1.1 | 5.3 | GO:1903385 | regulation of homophilic cell adhesion(GO:1903385) |
| 1.0 | 4.2 | GO:1902459 | positive regulation of stem cell population maintenance(GO:1902459) |
| 1.0 | 3.1 | GO:0031393 | negative regulation of prostaglandin biosynthetic process(GO:0031393) negative regulation of helicase activity(GO:0051097) negative regulation of response to alcohol(GO:1901420) |
| 1.0 | 4.1 | GO:0032804 | viral protein processing(GO:0019082) negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472) |
| 1.0 | 7.1 | GO:0015866 | ADP transport(GO:0015866) |
| 1.0 | 3.0 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
| 1.0 | 9.0 | GO:0035897 | proteolysis in other organism(GO:0035897) |
| 1.0 | 4.0 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
| 1.0 | 7.9 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
| 1.0 | 3.9 | GO:0018201 | N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201) |
| 1.0 | 3.9 | GO:0035740 | CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) |
| 1.0 | 6.8 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
| 0.9 | 1.8 | GO:0072172 | ureteric bud formation(GO:0060676) regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107) mesonephric tubule formation(GO:0072172) |
| 0.9 | 2.7 | GO:2000687 | negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687) |
| 0.9 | 3.6 | GO:1900127 | positive regulation of hyaluronan biosynthetic process(GO:1900127) |
| 0.9 | 4.4 | GO:0098706 | ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706) |
| 0.9 | 0.9 | GO:0061054 | dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) positive regulation of dermatome development(GO:0061184) |
| 0.9 | 2.6 | GO:0071921 | establishment of sister chromatid cohesion(GO:0034085) regulation of chromosome condensation(GO:0060623) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922) |
| 0.9 | 2.6 | GO:0016344 | meiotic chromosome movement towards spindle pole(GO:0016344) |
| 0.9 | 2.6 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
| 0.8 | 2.5 | GO:0015917 | aminophospholipid transport(GO:0015917) |
| 0.8 | 2.5 | GO:1901674 | histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674) |
| 0.8 | 4.9 | GO:0010637 | negative regulation of mitochondrial fusion(GO:0010637) |
| 0.8 | 2.4 | GO:0048865 | stem cell fate commitment(GO:0048865) |
| 0.8 | 11.4 | GO:0090136 | epithelial cell-cell adhesion(GO:0090136) |
| 0.8 | 15.1 | GO:0019511 | peptidyl-proline hydroxylation(GO:0019511) |
| 0.8 | 2.3 | GO:1904502 | regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504) |
| 0.7 | 20.8 | GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) |
| 0.7 | 2.2 | GO:0048294 | negative regulation of isotype switching to IgE isotypes(GO:0048294) |
| 0.7 | 2.2 | GO:1904339 | negative regulation of dopaminergic neuron differentiation(GO:1904339) |
| 0.7 | 6.6 | GO:0071578 | zinc II ion transmembrane import(GO:0071578) |
| 0.7 | 7.3 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.7 | 8.0 | GO:0042415 | norepinephrine metabolic process(GO:0042415) |
| 0.7 | 2.9 | GO:1904379 | protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379) |
| 0.7 | 3.6 | GO:0042986 | positive regulation of amyloid precursor protein biosynthetic process(GO:0042986) |
| 0.7 | 22.6 | GO:0071800 | podosome assembly(GO:0071800) |
| 0.7 | 2.1 | GO:0031064 | negative regulation of histone deacetylation(GO:0031064) |
| 0.7 | 2.8 | GO:1904382 | protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382) |
| 0.7 | 6.0 | GO:0071680 | response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681) |
| 0.7 | 3.3 | GO:0051138 | positive regulation of NK T cell differentiation(GO:0051138) |
| 0.7 | 2.0 | GO:0003420 | regulation of growth plate cartilage chondrocyte proliferation(GO:0003420) |
| 0.7 | 8.5 | GO:0036010 | protein localization to endosome(GO:0036010) |
| 0.6 | 4.5 | GO:1903593 | regulation of histamine secretion by mast cell(GO:1903593) |
| 0.6 | 2.5 | GO:0061086 | negative regulation of histone H3-K27 methylation(GO:0061086) |
| 0.6 | 3.8 | GO:0016560 | protein import into peroxisome matrix, docking(GO:0016560) |
| 0.6 | 8.1 | GO:1901978 | positive regulation of cell cycle checkpoint(GO:1901978) |
| 0.6 | 1.9 | GO:0042946 | glucoside transport(GO:0042946) |
| 0.6 | 7.4 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 0.6 | 5.4 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 0.6 | 10.1 | GO:0072498 | embryonic skeletal joint development(GO:0072498) |
| 0.6 | 4.1 | GO:2000381 | negative regulation of mesoderm development(GO:2000381) |
| 0.6 | 3.5 | GO:1904885 | beta-catenin destruction complex assembly(GO:1904885) |
| 0.6 | 2.9 | GO:0060355 | positive regulation of cell adhesion molecule production(GO:0060355) |
| 0.6 | 1.2 | GO:2001045 | negative regulation of integrin-mediated signaling pathway(GO:2001045) |
| 0.6 | 2.2 | GO:0045629 | negative regulation of T-helper 2 cell differentiation(GO:0045629) |
| 0.6 | 1.7 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
| 0.5 | 1.6 | GO:0006499 | N-terminal protein myristoylation(GO:0006499) |
| 0.5 | 1.6 | GO:0090118 | receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) |
| 0.5 | 2.6 | GO:1904059 | regulation of locomotor rhythm(GO:1904059) |
| 0.5 | 2.6 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 0.5 | 1.5 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
| 0.5 | 1.5 | GO:1901258 | positive regulation of granulocyte colony-stimulating factor production(GO:0071657) positive regulation of macrophage colony-stimulating factor production(GO:1901258) |
| 0.5 | 2.0 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
| 0.5 | 1.9 | GO:0048861 | leukemia inhibitory factor signaling pathway(GO:0048861) |
| 0.5 | 0.9 | GO:0061113 | pancreas morphogenesis(GO:0061113) |
| 0.5 | 14.1 | GO:0007176 | regulation of epidermal growth factor-activated receptor activity(GO:0007176) |
| 0.5 | 2.8 | GO:0030917 | midbrain-hindbrain boundary development(GO:0030917) |
| 0.5 | 4.6 | GO:0070933 | histone H4 deacetylation(GO:0070933) |
| 0.5 | 15.6 | GO:0042744 | hydrogen peroxide catabolic process(GO:0042744) |
| 0.5 | 1.8 | GO:0032455 | nerve growth factor processing(GO:0032455) |
| 0.5 | 1.8 | GO:0021937 | cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937) |
| 0.4 | 1.3 | GO:0015888 | thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934) |
| 0.4 | 2.2 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
| 0.4 | 1.8 | GO:1904117 | response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117) |
| 0.4 | 1.3 | GO:0070682 | proteasome regulatory particle assembly(GO:0070682) |
| 0.4 | 1.7 | GO:0021707 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
| 0.4 | 2.6 | GO:0002005 | angiotensin catabolic process in blood(GO:0002005) |
| 0.4 | 15.6 | GO:0048009 | insulin-like growth factor receptor signaling pathway(GO:0048009) |
| 0.4 | 1.3 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
| 0.4 | 1.6 | GO:1903976 | Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147) negative regulation of glial cell migration(GO:1903976) |
| 0.4 | 1.2 | GO:1902263 | apoptotic process involved in embryonic digit morphogenesis(GO:1902263) |
| 0.4 | 2.8 | GO:0045617 | negative regulation of keratinocyte differentiation(GO:0045617) |
| 0.4 | 9.1 | GO:0051923 | sulfation(GO:0051923) |
| 0.4 | 3.1 | GO:0015705 | iodide transport(GO:0015705) |
| 0.4 | 9.8 | GO:0006907 | pinocytosis(GO:0006907) |
| 0.4 | 1.5 | GO:0001957 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.4 | 1.5 | GO:0021965 | spinal cord ventral commissure morphogenesis(GO:0021965) dorsal/ventral axon guidance(GO:0033563) |
| 0.4 | 4.4 | GO:0035360 | positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360) |
| 0.4 | 4.4 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 0.4 | 6.2 | GO:0036149 | phosphatidylinositol acyl-chain remodeling(GO:0036149) |
| 0.4 | 1.4 | GO:0070940 | dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940) |
| 0.4 | 6.4 | GO:0097369 | sodium ion import(GO:0097369) |
| 0.4 | 3.2 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.4 | 1.4 | GO:0014859 | negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) |
| 0.4 | 6.0 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.3 | 1.4 | GO:0002904 | positive regulation of B cell apoptotic process(GO:0002904) |
| 0.3 | 2.3 | GO:0010998 | regulation of translational initiation by eIF2 alpha phosphorylation(GO:0010998) |
| 0.3 | 6.9 | GO:1902894 | negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894) |
| 0.3 | 6.6 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.3 | 3.2 | GO:0019064 | fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800) |
| 0.3 | 6.8 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
| 0.3 | 5.3 | GO:0071670 | smooth muscle cell chemotaxis(GO:0071670) |
| 0.3 | 0.6 | GO:0060061 | Spemann organizer formation(GO:0060061) |
| 0.3 | 2.8 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 0.3 | 5.1 | GO:0043586 | tongue development(GO:0043586) |
| 0.3 | 6.0 | GO:0032486 | Rap protein signal transduction(GO:0032486) |
| 0.3 | 9.8 | GO:0046653 | tetrahydrofolate metabolic process(GO:0046653) |
| 0.3 | 1.1 | GO:0002349 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
| 0.3 | 1.4 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.3 | 5.0 | GO:0006002 | fructose 6-phosphate metabolic process(GO:0006002) |
| 0.3 | 1.4 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
| 0.3 | 4.1 | GO:0097201 | negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201) |
| 0.3 | 0.8 | GO:2001226 | negative regulation of chloride transport(GO:2001226) |
| 0.3 | 29.6 | GO:0002062 | chondrocyte differentiation(GO:0002062) |
| 0.3 | 3.9 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
| 0.3 | 3.6 | GO:0021957 | corticospinal tract morphogenesis(GO:0021957) |
| 0.3 | 1.0 | GO:1900450 | inactivation of MAPKK activity(GO:0051389) negative regulation of glutamate receptor signaling pathway(GO:1900450) negative regulation of NMDA glutamate receptor activity(GO:1904782) |
| 0.3 | 0.8 | GO:0051534 | negative regulation of NFAT protein import into nucleus(GO:0051534) |
| 0.3 | 2.0 | GO:0045905 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
| 0.2 | 1.5 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
| 0.2 | 4.7 | GO:0060211 | regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213) |
| 0.2 | 0.7 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) |
| 0.2 | 1.9 | GO:0031087 | deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087) |
| 0.2 | 0.7 | GO:1904017 | cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 0.2 | 0.7 | GO:0071529 | cementum mineralization(GO:0071529) |
| 0.2 | 0.7 | GO:0051182 | coenzyme transport(GO:0051182) |
| 0.2 | 1.1 | GO:0023019 | signal transduction involved in regulation of gene expression(GO:0023019) |
| 0.2 | 5.4 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
| 0.2 | 8.7 | GO:0032007 | negative regulation of TOR signaling(GO:0032007) |
| 0.2 | 1.5 | GO:1901314 | negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915) |
| 0.2 | 0.6 | GO:0061502 | early endosome to recycling endosome transport(GO:0061502) |
| 0.2 | 21.2 | GO:0042035 | regulation of cytokine biosynthetic process(GO:0042035) |
| 0.2 | 2.9 | GO:0060736 | prostate gland growth(GO:0060736) |
| 0.2 | 0.6 | GO:0003344 | pericardium morphogenesis(GO:0003344) |
| 0.2 | 0.8 | GO:0016240 | autophagosome docking(GO:0016240) |
| 0.2 | 5.9 | GO:0015721 | bile acid and bile salt transport(GO:0015721) |
| 0.2 | 0.9 | GO:0006015 | 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391) |
| 0.2 | 1.6 | GO:0060148 | positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637) |
| 0.2 | 3.8 | GO:0035518 | histone H2A monoubiquitination(GO:0035518) |
| 0.2 | 3.4 | GO:0034656 | nucleobase-containing small molecule catabolic process(GO:0034656) |
| 0.2 | 1.8 | GO:0051964 | negative regulation of synapse assembly(GO:0051964) |
| 0.2 | 0.9 | GO:0060340 | positive regulation of type I interferon-mediated signaling pathway(GO:0060340) |
| 0.2 | 12.4 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.2 | 24.7 | GO:0006406 | mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427) |
| 0.2 | 1.0 | GO:1903566 | positive regulation of protein localization to cilium(GO:1903566) |
| 0.2 | 5.3 | GO:0006337 | nucleosome disassembly(GO:0006337) |
| 0.2 | 0.9 | GO:0031291 | Ran protein signal transduction(GO:0031291) |
| 0.2 | 2.9 | GO:2000811 | negative regulation of anoikis(GO:2000811) |
| 0.2 | 3.4 | GO:0030828 | positive regulation of cGMP biosynthetic process(GO:0030828) |
| 0.2 | 1.7 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
| 0.2 | 3.0 | GO:0017121 | phospholipid scrambling(GO:0017121) |
| 0.2 | 24.5 | GO:0030509 | BMP signaling pathway(GO:0030509) |
| 0.2 | 0.7 | GO:0090283 | regulation of protein glycosylation in Golgi(GO:0090283) |
| 0.2 | 3.1 | GO:1900745 | positive regulation of p38MAPK cascade(GO:1900745) |
| 0.2 | 1.8 | GO:0010862 | positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) |
| 0.2 | 1.8 | GO:0048934 | peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935) |
| 0.2 | 0.6 | GO:0031507 | heterochromatin assembly(GO:0031507) |
| 0.2 | 0.8 | GO:0072423 | response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) |
| 0.2 | 0.6 | GO:0071110 | protein biotinylation(GO:0009305) histone biotinylation(GO:0071110) |
| 0.2 | 2.1 | GO:0021694 | cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) regulation of cholesterol homeostasis(GO:2000188) |
| 0.2 | 2.5 | GO:0071880 | adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880) |
| 0.2 | 1.2 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
| 0.2 | 1.6 | GO:0051005 | negative regulation of lipoprotein lipase activity(GO:0051005) |
| 0.2 | 6.6 | GO:0071480 | cellular response to gamma radiation(GO:0071480) |
| 0.1 | 6.2 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.1 | 1.0 | GO:0046940 | nucleoside monophosphate phosphorylation(GO:0046940) |
| 0.1 | 1.3 | GO:0046827 | positive regulation of protein export from nucleus(GO:0046827) |
| 0.1 | 2.0 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.1 | 1.0 | GO:1903433 | regulation of constitutive secretory pathway(GO:1903433) |
| 0.1 | 1.1 | GO:0033629 | negative regulation of cell adhesion mediated by integrin(GO:0033629) |
| 0.1 | 6.8 | GO:0010761 | fibroblast migration(GO:0010761) |
| 0.1 | 1.5 | GO:0032025 | response to cobalt ion(GO:0032025) |
| 0.1 | 5.7 | GO:0051123 | RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123) |
| 0.1 | 4.5 | GO:0070979 | protein K11-linked ubiquitination(GO:0070979) |
| 0.1 | 2.2 | GO:0008228 | opsonization(GO:0008228) |
| 0.1 | 2.0 | GO:0098969 | neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540) |
| 0.1 | 3.9 | GO:0015991 | energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) |
| 0.1 | 3.1 | GO:0030214 | hyaluronan catabolic process(GO:0030214) |
| 0.1 | 1.2 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 0.1 | 1.3 | GO:0006824 | cobalt ion transport(GO:0006824) |
| 0.1 | 1.7 | GO:0043508 | negative regulation of JUN kinase activity(GO:0043508) |
| 0.1 | 1.7 | GO:0021680 | cerebellar Purkinje cell layer development(GO:0021680) |
| 0.1 | 3.1 | GO:0048635 | negative regulation of muscle organ development(GO:0048635) |
| 0.1 | 0.6 | GO:0033299 | secretion of lysosomal enzymes(GO:0033299) |
| 0.1 | 0.6 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.1 | 6.6 | GO:0035914 | skeletal muscle cell differentiation(GO:0035914) |
| 0.1 | 4.6 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
| 0.1 | 7.0 | GO:0007368 | determination of left/right symmetry(GO:0007368) |
| 0.1 | 1.3 | GO:0021794 | thalamus development(GO:0021794) |
| 0.1 | 0.5 | GO:0060242 | contact inhibition(GO:0060242) |
| 0.1 | 0.9 | GO:0051481 | negative regulation of cytosolic calcium ion concentration(GO:0051481) |
| 0.1 | 5.2 | GO:0045445 | myoblast differentiation(GO:0045445) |
| 0.1 | 1.2 | GO:0035162 | embryonic hemopoiesis(GO:0035162) |
| 0.1 | 1.9 | GO:0097503 | sialylation(GO:0097503) |
| 0.1 | 3.0 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
| 0.1 | 3.2 | GO:0060119 | inner ear receptor cell development(GO:0060119) |
| 0.1 | 0.6 | GO:0090204 | protein localization to nuclear pore(GO:0090204) |
| 0.1 | 0.4 | GO:2000645 | negative regulation of receptor catabolic process(GO:2000645) |
| 0.1 | 6.9 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) |
| 0.1 | 6.3 | GO:0048208 | vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208) |
| 0.1 | 0.8 | GO:0006451 | selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451) |
| 0.1 | 3.6 | GO:0061718 | NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718) |
| 0.1 | 0.4 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
| 0.1 | 1.2 | GO:0060081 | membrane hyperpolarization(GO:0060081) |
| 0.1 | 2.2 | GO:0030970 | retrograde protein transport, ER to cytosol(GO:0030970) |
| 0.1 | 1.5 | GO:0051016 | barbed-end actin filament capping(GO:0051016) |
| 0.1 | 0.8 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 0.1 | 1.5 | GO:0045109 | intermediate filament organization(GO:0045109) |
| 0.1 | 0.3 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
| 0.1 | 10.4 | GO:0006613 | cotranslational protein targeting to membrane(GO:0006613) |
| 0.1 | 1.1 | GO:0045116 | protein neddylation(GO:0045116) |
| 0.1 | 4.3 | GO:0009301 | snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.1 | 0.6 | GO:0031584 | activation of phospholipase D activity(GO:0031584) |
| 0.1 | 0.5 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
| 0.1 | 0.6 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
| 0.1 | 1.6 | GO:0002755 | MyD88-dependent toll-like receptor signaling pathway(GO:0002755) |
| 0.1 | 0.7 | GO:0010867 | positive regulation of triglyceride biosynthetic process(GO:0010867) |
| 0.1 | 1.0 | GO:0045332 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.1 | 0.2 | GO:0031053 | primary miRNA processing(GO:0031053) |
| 0.1 | 0.5 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.1 | 3.0 | GO:0006400 | tRNA modification(GO:0006400) |
| 0.1 | 0.2 | GO:0006550 | isoleucine catabolic process(GO:0006550) |
| 0.0 | 0.6 | GO:0051934 | dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494) |
| 0.0 | 0.2 | GO:1904381 | Golgi apparatus mannose trimming(GO:1904381) |
| 0.0 | 5.4 | GO:0007588 | excretion(GO:0007588) |
| 0.0 | 0.1 | GO:0032849 | regulation of cellular pH reduction(GO:0032847) positive regulation of cellular pH reduction(GO:0032849) |
| 0.0 | 0.3 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
| 0.0 | 0.6 | GO:0002115 | store-operated calcium entry(GO:0002115) |
| 0.0 | 0.3 | GO:0045717 | negative regulation of fatty acid biosynthetic process(GO:0045717) |
| 0.0 | 0.4 | GO:0044387 | negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387) |
| 0.0 | 0.4 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.0 | 1.7 | GO:0032760 | positive regulation of tumor necrosis factor production(GO:0032760) |
| 0.0 | 0.3 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.0 | 0.8 | GO:2000144 | positive regulation of DNA-templated transcription, initiation(GO:2000144) |
| 0.0 | 1.1 | GO:0051353 | positive regulation of oxidoreductase activity(GO:0051353) |
| 0.0 | 0.4 | GO:0060019 | radial glial cell differentiation(GO:0060019) |
| 0.0 | 0.7 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
| 0.0 | 2.6 | GO:1902017 | regulation of cilium assembly(GO:1902017) |
| 0.0 | 0.7 | GO:0007520 | myoblast fusion(GO:0007520) |
| 0.0 | 0.4 | GO:0036500 | ATF6-mediated unfolded protein response(GO:0036500) |
| 0.0 | 1.2 | GO:0051496 | positive regulation of stress fiber assembly(GO:0051496) |
| 0.0 | 0.4 | GO:0035878 | nail development(GO:0035878) |
| 0.0 | 12.3 | GO:0006260 | DNA replication(GO:0006260) |
| 0.0 | 3.3 | GO:0090175 | Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175) |
| 0.0 | 0.9 | GO:1901998 | toxin transport(GO:1901998) |
| 0.0 | 5.6 | GO:0008360 | regulation of cell shape(GO:0008360) |
| 0.0 | 2.1 | GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process(GO:0043154) |
| 0.0 | 2.2 | GO:2000134 | negative regulation of cell cycle G1/S phase transition(GO:1902807) negative regulation of G1/S transition of mitotic cell cycle(GO:2000134) |
| 0.0 | 0.4 | GO:1990035 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
| 0.0 | 1.3 | GO:0050775 | positive regulation of dendrite morphogenesis(GO:0050775) |
| 0.0 | 2.1 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.0 | 0.4 | GO:0007084 | mitotic nuclear envelope reassembly(GO:0007084) |
| 0.0 | 1.5 | GO:0008625 | extrinsic apoptotic signaling pathway via death domain receptors(GO:0008625) |
| 0.0 | 0.2 | GO:0032000 | positive regulation of fatty acid beta-oxidation(GO:0032000) |
| 0.0 | 11.5 | GO:0043312 | neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312) |
| 0.0 | 0.6 | GO:0042733 | embryonic digit morphogenesis(GO:0042733) |
| 0.0 | 0.2 | GO:0043517 | positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517) |
| 0.0 | 0.0 | GO:0021571 | rhombomere 5 development(GO:0021571) |
| 0.0 | 0.3 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
| 0.0 | 1.2 | GO:0048706 | embryonic skeletal system development(GO:0048706) |
| 0.0 | 1.7 | GO:0030308 | negative regulation of cell growth(GO:0030308) |
| 0.0 | 0.1 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.0 | 0.4 | GO:0034080 | chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.0 | 0.0 | GO:0071286 | cellular response to magnesium ion(GO:0071286) |
| 0.0 | 0.5 | GO:0060996 | dendritic spine development(GO:0060996) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.2 | 12.7 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
| 2.8 | 19.9 | GO:0044354 | pinosome(GO:0044352) macropinosome(GO:0044354) |
| 2.7 | 29.3 | GO:0098651 | basement membrane collagen trimer(GO:0098651) |
| 2.5 | 12.4 | GO:0097513 | myosin II filament(GO:0097513) |
| 2.5 | 24.8 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 2.3 | 7.0 | GO:0043512 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 2.1 | 12.6 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 1.6 | 4.7 | GO:0017109 | glutamate-cysteine ligase complex(GO:0017109) |
| 1.5 | 4.5 | GO:0044609 | DBIRD complex(GO:0044609) |
| 1.4 | 4.2 | GO:0071148 | TEAD-1-YAP complex(GO:0071148) |
| 1.1 | 21.9 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 1.0 | 7.2 | GO:0035985 | senescence-associated heterochromatin focus(GO:0035985) |
| 1.0 | 9.6 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.9 | 3.8 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 0.9 | 0.9 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 0.9 | 4.7 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
| 0.9 | 5.3 | GO:0032010 | phagolysosome(GO:0032010) |
| 0.8 | 6.6 | GO:0005579 | membrane attack complex(GO:0005579) |
| 0.7 | 2.8 | GO:1990075 | periciliary membrane compartment(GO:1990075) |
| 0.6 | 33.7 | GO:0002102 | podosome(GO:0002102) |
| 0.6 | 8.1 | GO:0090543 | Flemming body(GO:0090543) |
| 0.6 | 6.8 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.5 | 1.6 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
| 0.5 | 3.1 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.5 | 7.6 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.5 | 1.9 | GO:0044232 | organelle membrane contact site(GO:0044232) |
| 0.5 | 7.4 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.5 | 16.3 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.4 | 50.6 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.4 | 4.1 | GO:0016593 | Cdc73/Paf1 complex(GO:0016593) |
| 0.4 | 4.6 | GO:0042555 | MCM complex(GO:0042555) |
| 0.4 | 4.2 | GO:0071203 | WASH complex(GO:0071203) |
| 0.3 | 3.4 | GO:0008278 | cohesin complex(GO:0008278) |
| 0.3 | 3.6 | GO:0035749 | myelin sheath adaxonal region(GO:0035749) |
| 0.3 | 2.3 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.3 | 2.2 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.3 | 5.1 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.3 | 5.5 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.3 | 5.4 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.3 | 3.9 | GO:0033177 | proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179) |
| 0.3 | 9.4 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.3 | 1.7 | GO:0032279 | axonemal microtubule(GO:0005879) asymmetric synapse(GO:0032279) |
| 0.3 | 19.4 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.3 | 5.0 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
| 0.2 | 15.6 | GO:0035577 | azurophil granule membrane(GO:0035577) |
| 0.2 | 21.8 | GO:0032580 | Golgi cisterna membrane(GO:0032580) |
| 0.2 | 3.3 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.2 | 0.9 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.2 | 0.7 | GO:0035517 | PR-DUB complex(GO:0035517) |
| 0.2 | 2.1 | GO:0019907 | cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907) |
| 0.2 | 15.0 | GO:0005844 | polysome(GO:0005844) |
| 0.2 | 0.9 | GO:0002189 | ribose phosphate diphosphokinase complex(GO:0002189) |
| 0.2 | 3.5 | GO:0034098 | VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098) |
| 0.2 | 7.2 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.2 | 63.7 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.2 | 17.2 | GO:0005604 | basement membrane(GO:0005604) |
| 0.2 | 2.4 | GO:0044300 | cerebellar mossy fiber(GO:0044300) |
| 0.2 | 0.7 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
| 0.2 | 5.6 | GO:0090665 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.2 | 5.3 | GO:0016514 | SWI/SNF complex(GO:0016514) |
| 0.2 | 2.0 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.2 | 2.3 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.1 | 7.5 | GO:0097610 | cleavage furrow(GO:0032154) cell surface furrow(GO:0097610) |
| 0.1 | 1.3 | GO:0000445 | THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445) |
| 0.1 | 2.5 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 8.7 | GO:0010494 | cytoplasmic stress granule(GO:0010494) |
| 0.1 | 1.1 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.1 | 0.5 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.1 | 2.5 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.1 | 4.2 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.1 | 0.5 | GO:0048179 | activin receptor complex(GO:0048179) |
| 0.1 | 4.1 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.1 | 2.3 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.1 | 6.9 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.1 | 0.6 | GO:0005677 | chromatin silencing complex(GO:0005677) |
| 0.1 | 0.4 | GO:0002945 | cyclin K-CDK13 complex(GO:0002945) |
| 0.1 | 19.6 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.1 | 6.1 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.1 | 1.2 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.1 | 0.8 | GO:0000796 | condensin complex(GO:0000796) |
| 0.1 | 4.4 | GO:0005771 | multivesicular body(GO:0005771) |
| 0.1 | 54.5 | GO:0005925 | focal adhesion(GO:0005925) |
| 0.1 | 43.6 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.1 | 2.5 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 0.4 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.1 | 5.6 | GO:0005902 | microvillus(GO:0005902) |
| 0.1 | 1.3 | GO:0008540 | proteasome regulatory particle, base subcomplex(GO:0008540) |
| 0.1 | 32.3 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.1 | 0.3 | GO:0030895 | apolipoprotein B mRNA editing enzyme complex(GO:0030895) |
| 0.1 | 9.0 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.1 | 3.6 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.1 | 3.3 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.1 | 3.0 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.1 | 1.2 | GO:0043194 | axon initial segment(GO:0043194) |
| 0.1 | 35.4 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.1 | 2.0 | GO:0016235 | aggresome(GO:0016235) |
| 0.1 | 4.9 | GO:0035578 | azurophil granule lumen(GO:0035578) |
| 0.1 | 7.3 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.0 | 3.8 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.0 | 1.9 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.0 | 4.0 | GO:0043657 | host(GO:0018995) host cell(GO:0043657) |
| 0.0 | 1.1 | GO:0045335 | phagocytic vesicle(GO:0045335) |
| 0.0 | 1.7 | GO:0098878 | ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878) |
| 0.0 | 3.7 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.0 | 0.2 | GO:0097059 | CNTFR-CLCF1 complex(GO:0097059) |
| 0.0 | 3.9 | GO:0030666 | endocytic vesicle membrane(GO:0030666) |
| 0.0 | 0.6 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.0 | 0.6 | GO:0005922 | connexon complex(GO:0005922) |
| 0.0 | 0.7 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.0 | 2.0 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
| 0.0 | 3.7 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.0 | 1.7 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 4.4 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 26.8 | GO:0005615 | extracellular space(GO:0005615) |
| 0.0 | 0.4 | GO:0030117 | membrane coat(GO:0030117) coated membrane(GO:0048475) |
| 0.0 | 2.0 | GO:0070160 | bicellular tight junction(GO:0005923) occluding junction(GO:0070160) |
| 0.0 | 0.7 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 0.8 | GO:0016591 | DNA-directed RNA polymerase II, holoenzyme(GO:0016591) |
| 0.0 | 2.6 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 2.6 | GO:0031968 | organelle outer membrane(GO:0031968) |
| 0.0 | 12.0 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.0 | 1.0 | GO:0000502 | proteasome complex(GO:0000502) |
| 0.0 | 0.6 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 0.2 | GO:0030870 | Mre11 complex(GO:0030870) |
| 0.0 | 1.1 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970) |
| 0.0 | 4.1 | GO:0005783 | endoplasmic reticulum(GO:0005783) |
| 0.0 | 4.9 | GO:0031966 | mitochondrial membrane(GO:0031966) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.2 | 15.6 | GO:0005010 | insulin-like growth factor-activated receptor activity(GO:0005010) |
| 4.1 | 12.4 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
| 4.0 | 12.1 | GO:0047757 | chondroitin-glucuronate 5-epimerase activity(GO:0047757) |
| 4.0 | 19.9 | GO:0019834 | phospholipase A2 inhibitor activity(GO:0019834) |
| 4.0 | 19.9 | GO:0008160 | protein tyrosine phosphatase activator activity(GO:0008160) |
| 3.1 | 21.9 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 3.1 | 15.6 | GO:0005152 | interleukin-1 receptor antagonist activity(GO:0005152) |
| 3.0 | 9.1 | GO:0050510 | N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510) |
| 2.6 | 7.9 | GO:0005017 | platelet-derived growth factor-activated receptor activity(GO:0005017) |
| 2.4 | 12.2 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) |
| 2.2 | 6.5 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
| 2.1 | 8.5 | GO:0004487 | methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488) |
| 1.9 | 5.7 | GO:0035575 | histone demethylase activity (H4-K20 specific)(GO:0035575) |
| 1.9 | 7.5 | GO:0004687 | myosin light chain kinase activity(GO:0004687) |
| 1.8 | 12.7 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
| 1.8 | 7.1 | GO:0004886 | 9-cis retinoic acid receptor activity(GO:0004886) vitamin D response element binding(GO:0070644) |
| 1.7 | 5.2 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 1.6 | 9.6 | GO:0038085 | vascular endothelial growth factor binding(GO:0038085) |
| 1.6 | 4.7 | GO:0004357 | glutamate-cysteine ligase activity(GO:0004357) |
| 1.5 | 5.9 | GO:0008508 | bile acid:sodium symporter activity(GO:0008508) |
| 1.5 | 5.9 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 1.4 | 7.2 | GO:0004677 | DNA-dependent protein kinase activity(GO:0004677) |
| 1.3 | 3.8 | GO:0004758 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 1.2 | 6.2 | GO:0031871 | proteinase activated receptor binding(GO:0031871) |
| 1.2 | 5.0 | GO:0004360 | glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360) |
| 1.2 | 7.4 | GO:0038049 | transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) |
| 1.2 | 3.6 | GO:0051717 | inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717) |
| 1.2 | 7.2 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 1.2 | 3.6 | GO:0034736 | sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736) |
| 1.1 | 4.5 | GO:0005111 | type 2 fibroblast growth factor receptor binding(GO:0005111) |
| 1.1 | 4.4 | GO:0052851 | cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851) |
| 1.1 | 6.6 | GO:0015093 | ferrous iron transmembrane transporter activity(GO:0015093) |
| 1.1 | 19.2 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
| 1.0 | 3.1 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
| 1.0 | 3.1 | GO:0004119 | cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) |
| 1.0 | 7.1 | GO:0005346 | adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217) |
| 1.0 | 14.6 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
| 1.0 | 3.9 | GO:0004379 | glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107) |
| 0.9 | 7.0 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.8 | 3.8 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.7 | 9.8 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.7 | 2.1 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
| 0.7 | 6.8 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.7 | 4.7 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.6 | 1.9 | GO:0004923 | leukemia inhibitory factor receptor activity(GO:0004923) |
| 0.6 | 3.1 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.6 | 1.9 | GO:0042947 | glucoside transmembrane transporter activity(GO:0042947) |
| 0.6 | 5.5 | GO:0019158 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.6 | 3.6 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.6 | 12.4 | GO:0043495 | protein anchor(GO:0043495) |
| 0.6 | 4.1 | GO:0098988 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988) |
| 0.6 | 5.1 | GO:0030274 | LIM domain binding(GO:0030274) |
| 0.6 | 2.2 | GO:0035473 | lipase binding(GO:0035473) |
| 0.5 | 20.7 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.5 | 2.1 | GO:0005169 | neurotrophin TRKB receptor binding(GO:0005169) |
| 0.5 | 1.6 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
| 0.5 | 4.7 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
| 0.5 | 7.6 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
| 0.5 | 1.5 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.5 | 1.9 | GO:0099580 | ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580) |
| 0.5 | 9.2 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.5 | 2.9 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.4 | 1.3 | GO:0015563 | thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563) |
| 0.4 | 11.1 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.4 | 3.0 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 0.4 | 1.3 | GO:0070905 | serine binding(GO:0070905) |
| 0.4 | 2.1 | GO:0034647 | histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647) |
| 0.4 | 1.7 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
| 0.4 | 32.1 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.4 | 10.0 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.4 | 7.5 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.4 | 2.3 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.4 | 15.7 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.4 | 29.0 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.4 | 5.7 | GO:0048406 | nerve growth factor binding(GO:0048406) |
| 0.4 | 1.5 | GO:0019798 | procollagen-proline dioxygenase activity(GO:0019798) |
| 0.4 | 1.9 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 0.4 | 1.1 | GO:0030226 | apolipoprotein receptor activity(GO:0030226) |
| 0.4 | 3.0 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.4 | 1.5 | GO:0050659 | N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659) |
| 0.4 | 2.9 | GO:0005534 | galactose binding(GO:0005534) |
| 0.4 | 2.5 | GO:0050815 | phosphoserine binding(GO:0050815) |
| 0.4 | 9.2 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.4 | 4.6 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.3 | 8.7 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.3 | 1.4 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.3 | 4.4 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.3 | 3.3 | GO:0015386 | sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.3 | 3.2 | GO:0032027 | myosin light chain binding(GO:0032027) |
| 0.3 | 3.2 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
| 0.3 | 4.2 | GO:0001075 | transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) |
| 0.3 | 0.8 | GO:0004382 | guanosine-diphosphatase activity(GO:0004382) |
| 0.3 | 1.6 | GO:0033592 | RNA strand annealing activity(GO:0033592) |
| 0.3 | 8.5 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.3 | 2.0 | GO:0071253 | connexin binding(GO:0071253) |
| 0.3 | 1.8 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.2 | 3.7 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
| 0.2 | 9.0 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.2 | 4.4 | GO:0008327 | methyl-CpG binding(GO:0008327) |
| 0.2 | 15.2 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.2 | 1.2 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 0.2 | 6.0 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 0.2 | 4.7 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.2 | 0.7 | GO:0010861 | thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) |
| 0.2 | 0.7 | GO:0008523 | sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) |
| 0.2 | 1.8 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.2 | 2.0 | GO:0035242 | protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
| 0.2 | 2.0 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
| 0.2 | 35.6 | GO:0003697 | single-stranded DNA binding(GO:0003697) |
| 0.2 | 0.6 | GO:0001224 | RNA polymerase II transcription cofactor binding(GO:0001224) RNA polymerase II transcription corepressor binding(GO:0001226) |
| 0.2 | 4.6 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.2 | 2.9 | GO:0061578 | Lys63-specific deubiquitinase activity(GO:0061578) |
| 0.2 | 1.0 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.2 | 1.0 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
| 0.2 | 4.7 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
| 0.2 | 2.2 | GO:0044213 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 0.2 | 3.3 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.2 | 1.2 | GO:0072542 | protein phosphatase activator activity(GO:0072542) |
| 0.2 | 6.5 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.2 | 3.0 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
| 0.2 | 2.2 | GO:0070053 | thrombospondin receptor activity(GO:0070053) |
| 0.2 | 3.7 | GO:0001221 | transcription cofactor binding(GO:0001221) |
| 0.2 | 4.2 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.2 | 1.3 | GO:0004017 | adenylate kinase activity(GO:0004017) |
| 0.2 | 1.3 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.2 | 8.9 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.2 | 6.2 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
| 0.2 | 1.4 | GO:0031545 | peptidyl-proline 4-dioxygenase activity(GO:0031545) |
| 0.2 | 0.5 | GO:0044547 | DNA topoisomerase binding(GO:0044547) |
| 0.2 | 1.7 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.2 | 1.3 | GO:0019966 | interleukin-1 binding(GO:0019966) |
| 0.2 | 5.5 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.2 | 3.4 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
| 0.2 | 0.8 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.2 | 0.6 | GO:0005334 | norepinephrine:sodium symporter activity(GO:0005334) |
| 0.2 | 0.5 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.2 | 0.8 | GO:0004800 | thyroxine 5'-deiodinase activity(GO:0004800) |
| 0.2 | 0.8 | GO:0051998 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 0.2 | 5.3 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.2 | 6.5 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.2 | 0.8 | GO:0036033 | mediator complex binding(GO:0036033) |
| 0.2 | 0.6 | GO:0004079 | biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271) |
| 0.2 | 6.9 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.2 | 4.3 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.2 | 1.7 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.1 | 3.9 | GO:0044769 | ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961) |
| 0.1 | 0.9 | GO:0004749 | ribose phosphate diphosphokinase activity(GO:0004749) |
| 0.1 | 7.6 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.1 | 5.0 | GO:0017025 | TBP-class protein binding(GO:0017025) |
| 0.1 | 6.8 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.1 | 5.7 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.1 | 15.6 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.1 | 2.1 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
| 0.1 | 1.9 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
| 0.1 | 4.2 | GO:0046875 | ephrin receptor binding(GO:0046875) |
| 0.1 | 0.1 | GO:0019238 | cyclohydrolase activity(GO:0019238) |
| 0.1 | 0.1 | GO:0016532 | superoxide dismutase copper chaperone activity(GO:0016532) |
| 0.1 | 2.8 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.1 | 1.6 | GO:0017110 | nucleoside-diphosphatase activity(GO:0017110) |
| 0.1 | 0.9 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.1 | 0.4 | GO:0015275 | stretch-activated, cation-selective, calcium channel activity(GO:0015275) |
| 0.1 | 7.2 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.1 | 1.7 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.1 | 32.5 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
| 0.1 | 0.7 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.1 | 2.6 | GO:0004659 | prenyltransferase activity(GO:0004659) |
| 0.1 | 1.9 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.1 | 16.2 | GO:0008201 | heparin binding(GO:0008201) |
| 0.1 | 1.6 | GO:0097016 | L27 domain binding(GO:0097016) |
| 0.1 | 0.3 | GO:0001601 | peptide YY receptor activity(GO:0001601) |
| 0.1 | 0.9 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.1 | 1.6 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.1 | 1.1 | GO:0016594 | glycine binding(GO:0016594) |
| 0.1 | 3.4 | GO:0003705 | transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705) |
| 0.1 | 2.0 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.1 | 1.4 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.1 | 0.9 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.1 | 0.3 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 0.1 | 1.6 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.1 | 0.8 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.1 | 36.5 | GO:0045296 | cadherin binding(GO:0045296) |
| 0.1 | 0.2 | GO:0032427 | GBD domain binding(GO:0032427) |
| 0.1 | 1.7 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.1 | 15.1 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.1 | 24.8 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.1 | 0.6 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.1 | 2.9 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.1 | 1.2 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.1 | 22.5 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.1 | 2.0 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.1 | 1.7 | GO:0046966 | thyroid hormone receptor binding(GO:0046966) |
| 0.1 | 1.4 | GO:0051019 | mitogen-activated protein kinase binding(GO:0051019) |
| 0.1 | 0.9 | GO:0019534 | toxin transporter activity(GO:0019534) |
| 0.1 | 1.0 | GO:0043422 | protein kinase B binding(GO:0043422) |
| 0.1 | 1.1 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.1 | 2.1 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.1 | 6.3 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.1 | 0.6 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.1 | 7.0 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.1 | 2.7 | GO:0004702 | receptor signaling protein serine/threonine kinase activity(GO:0004702) |
| 0.1 | 0.4 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.1 | 0.8 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.1 | 20.1 | GO:0043565 | sequence-specific DNA binding(GO:0043565) |
| 0.1 | 1.5 | GO:0000049 | tRNA binding(GO:0000049) |
| 0.1 | 1.3 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.1 | 0.6 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.0 | 0.9 | GO:0033613 | activating transcription factor binding(GO:0033613) |
| 0.0 | 0.5 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 0.0 | 0.2 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.0 | 0.2 | GO:0016807 | cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004) |
| 0.0 | 1.9 | GO:0030145 | manganese ion binding(GO:0030145) |
| 0.0 | 1.1 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
| 0.0 | 0.1 | GO:0000982 | transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982) |
| 0.0 | 0.7 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.0 | 0.6 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 2.6 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 0.2 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) |
| 0.0 | 0.2 | GO:0032296 | ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296) primary miRNA binding(GO:0070878) |
| 0.0 | 0.4 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.0 | 0.9 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.0 | 0.2 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.0 | 0.9 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.0 | 0.9 | GO:0003690 | double-stranded DNA binding(GO:0003690) |
| 0.0 | 0.1 | GO:0070411 | I-SMAD binding(GO:0070411) |
| 0.0 | 3.8 | GO:0003713 | transcription coactivator activity(GO:0003713) |
| 0.0 | 0.4 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.0 | 0.2 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
| 0.0 | 1.4 | GO:0001618 | virus receptor activity(GO:0001618) |
| 0.0 | 0.4 | GO:0008138 | protein tyrosine/serine/threonine phosphatase activity(GO:0008138) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 69.8 | PID INTEGRIN3 PATHWAY | Beta3 integrin cell surface interactions |
| 1.0 | 19.1 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.9 | 21.3 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.8 | 29.3 | NABA BASEMENT MEMBRANES | Genes encoding structural components of basement membranes |
| 0.7 | 9.6 | PID VEGF VEGFR PATHWAY | VEGF and VEGFR signaling network |
| 0.6 | 25.7 | PID EPHA2 FWD PATHWAY | EPHA2 forward signaling |
| 0.6 | 29.4 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.5 | 14.9 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.4 | 33.5 | PID DELTA NP63 PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
| 0.3 | 22.8 | PID ECADHERIN STABILIZATION PATHWAY | Stabilization and expansion of the E-cadherin adherens junction |
| 0.3 | 14.2 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.3 | 13.3 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.3 | 9.0 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.3 | 3.6 | SA PTEN PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.3 | 2.6 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 0.3 | 3.6 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 0.3 | 4.3 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.2 | 22.4 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.2 | 10.9 | PID BMP PATHWAY | BMP receptor signaling |
| 0.2 | 10.6 | ST P38 MAPK PATHWAY | p38 MAPK Pathway |
| 0.2 | 4.7 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.2 | 36.7 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.2 | 9.1 | PID HIF2PATHWAY | HIF-2-alpha transcription factor network |
| 0.2 | 1.4 | SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES | Genes related to the insulin receptor pathway |
| 0.2 | 11.3 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.2 | 7.1 | PID ALK1 PATHWAY | ALK1 signaling events |
| 0.2 | 7.4 | PID MAPK TRK PATHWAY | Trk receptor signaling mediated by the MAPK pathway |
| 0.2 | 8.4 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.2 | 3.1 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.2 | 8.0 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.2 | 9.7 | PID NOTCH PATHWAY | Notch signaling pathway |
| 0.1 | 25.0 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 9.7 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 3.9 | PID EPHA FWDPATHWAY | EPHA forward signaling |
| 0.1 | 1.6 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.1 | 7.2 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.1 | 3.9 | PID IFNG PATHWAY | IFN-gamma pathway |
| 0.1 | 1.2 | PID NETRIN PATHWAY | Netrin-mediated signaling events |
| 0.1 | 28.5 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 1.2 | PID EPO PATHWAY | EPO signaling pathway |
| 0.1 | 1.2 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.1 | 5.6 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.1 | 0.6 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.1 | 1.1 | PID PS1 PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.1 | 1.3 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.1 | 26.3 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.1 | 0.9 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 4.4 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.1 | 0.4 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
| 0.1 | 3.7 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.1 | 3.1 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.1 | 0.3 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.1 | 0.6 | SA G2 AND M PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.1 | 5.7 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 5.2 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.1 | 2.7 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 6.9 | PID P53 DOWNSTREAM PATHWAY | Direct p53 effectors |
| 0.0 | 2.4 | PID HNF3A PATHWAY | FOXA1 transcription factor network |
| 0.0 | 1.5 | ST FAS SIGNALING PATHWAY | Fas Signaling Pathway |
| 0.0 | 0.8 | PID ATM PATHWAY | ATM pathway |
| 0.0 | 1.6 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 0.5 | PID VEGFR1 2 PATHWAY | Signaling events mediated by VEGFR1 and VEGFR2 |
| 0.0 | 0.2 | PID INSULIN PATHWAY | Insulin Pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 28.3 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 1.1 | 13.2 | REACTOME GLYCOPROTEIN HORMONES | Genes involved in Glycoprotein hormones |
| 1.1 | 28.5 | REACTOME HS GAG DEGRADATION | Genes involved in HS-GAG degradation |
| 0.9 | 23.3 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 0.9 | 3.6 | REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK | Genes involved in Negative regulation of the PI3K/AKT network |
| 0.7 | 12.6 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.7 | 31.4 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.7 | 21.2 | REACTOME CHONDROITIN SULFATE BIOSYNTHESIS | Genes involved in Chondroitin sulfate biosynthesis |
| 0.7 | 19.7 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.7 | 7.4 | REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR | Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor |
| 0.6 | 15.1 | REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
| 0.6 | 8.8 | REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM | Genes involved in Chondroitin sulfate/dermatan sulfate metabolism |
| 0.6 | 26.3 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.6 | 14.5 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.6 | 3.9 | REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS | Genes involved in Membrane binding and targetting of GAG proteins |
| 0.5 | 3.2 | REACTOME BINDING AND ENTRY OF HIV VIRION | Genes involved in Binding and entry of HIV virion |
| 0.5 | 12.7 | REACTOME SHC1 EVENTS IN EGFR SIGNALING | Genes involved in SHC1 events in EGFR signaling |
| 0.5 | 9.3 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.5 | 6.0 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.4 | 29.0 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.4 | 19.7 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.4 | 12.4 | REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.4 | 6.2 | REACTOME HEPARAN SULFATE HEPARIN HS GAG METABOLISM | Genes involved in Heparan sulfate/heparin (HS-GAG) metabolism |
| 0.4 | 6.2 | REACTOME ACYL CHAIN REMODELLING OF PI | Genes involved in Acyl chain remodelling of PI |
| 0.4 | 21.5 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.3 | 4.3 | REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY | Genes involved in Adenylate cyclase activating pathway |
| 0.3 | 11.6 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |
| 0.3 | 9.6 | REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
| 0.3 | 4.5 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.3 | 4.6 | REACTOME ERKS ARE INACTIVATED | Genes involved in ERKs are inactivated |
| 0.3 | 8.3 | REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING | Genes involved in Transferrin endocytosis and recycling |
| 0.3 | 6.8 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.2 | 4.2 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.2 | 11.4 | REACTOME O LINKED GLYCOSYLATION OF MUCINS | Genes involved in O-linked glycosylation of mucins |
| 0.2 | 1.4 | REACTOME SPRY REGULATION OF FGF SIGNALING | Genes involved in Spry regulation of FGF signaling |
| 0.2 | 3.5 | REACTOME CTNNB1 PHOSPHORYLATION CASCADE | Genes involved in Beta-catenin phosphorylation cascade |
| 0.2 | 3.2 | REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION | Genes involved in Nuclear Events (kinase and transcription factor activation) |
| 0.2 | 2.8 | REACTOME CALNEXIN CALRETICULIN CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.2 | 0.9 | REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS | Genes involved in Transport of Ribonucleoproteins into the Host Nucleus |
| 0.2 | 4.2 | REACTOME HYALURONAN METABOLISM | Genes involved in Hyaluronan metabolism |
| 0.2 | 2.4 | REACTOME RNA POL III TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase III Transcription Termination |
| 0.2 | 8.3 | REACTOME GENERATION OF SECOND MESSENGER MOLECULES | Genes involved in Generation of second messenger molecules |
| 0.2 | 2.9 | REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX | Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex |
| 0.2 | 5.3 | REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.2 | 4.2 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.2 | 1.5 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.2 | 1.5 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.2 | 12.5 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.2 | 2.5 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 1.8 | REACTOME TRANS GOLGI NETWORK VESICLE BUDDING | Genes involved in trans-Golgi Network Vesicle Budding |
| 0.1 | 6.6 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.1 | 4.1 | REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS | Genes involved in Ionotropic activity of Kainate Receptors |
| 0.1 | 1.6 | REACTOME TRAF6 MEDIATED NFKB ACTIVATION | Genes involved in TRAF6 mediated NF-kB activation |
| 0.1 | 1.2 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.1 | 2.2 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.1 | 4.7 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.1 | 4.0 | REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER | Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter |
| 0.1 | 0.9 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.1 | 19.1 | REACTOME DIABETES PATHWAYS | Genes involved in Diabetes pathways |
| 0.1 | 6.1 | REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION | Genes involved in Transport to the Golgi and subsequent modification |
| 0.1 | 1.6 | REACTOME GPVI MEDIATED ACTIVATION CASCADE | Genes involved in GPVI-mediated activation cascade |
| 0.1 | 6.5 | REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE | Genes involved in Nitric oxide stimulates guanylate cyclase |
| 0.1 | 2.7 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.1 | 3.3 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.1 | 3.9 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.1 | 9.0 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 0.6 | REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX | Genes involved in Formation of the HIV-1 Early Elongation Complex |
| 0.1 | 3.6 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 4.8 | REACTOME GLUCOSE TRANSPORT | Genes involved in Glucose transport |
| 0.1 | 4.2 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.1 | 1.6 | REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY | Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity |
| 0.1 | 3.1 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.1 | 0.2 | REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION | Genes involved in RORA Activates Circadian Expression |
| 0.1 | 6.0 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.1 | 1.9 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 0.1 | 1.1 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.1 | 1.2 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.1 | 5.7 | REACTOME DOWNSTREAM SIGNAL TRANSDUCTION | Genes involved in Downstream signal transduction |
| 0.1 | 10.4 | REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE | Genes involved in SRP-dependent cotranslational protein targeting to membrane |
| 0.1 | 1.6 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 0.1 | 2.0 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.1 | 2.5 | REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.0 | 0.5 | REACTOME OPSINS | Genes involved in Opsins |
| 0.0 | 0.9 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 0.0 | 1.6 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.0 | 0.8 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.0 | 1.5 | REACTOME NETRIN1 SIGNALING | Genes involved in Netrin-1 signaling |
| 0.0 | 1.4 | REACTOME DEADENYLATION OF MRNA | Genes involved in Deadenylation of mRNA |
| 0.0 | 0.3 | REACTOME MRNA PROCESSING | Genes involved in mRNA Processing |
| 0.0 | 1.1 | REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 0.9 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.0 | 0.6 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.0 | 0.4 | REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE | Genes involved in Synthesis of PIPs at the late endosome membrane |
| 0.0 | 0.1 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.0 | 0.9 | REACTOME BASIGIN INTERACTIONS | Genes involved in Basigin interactions |
| 0.0 | 0.2 | REACTOME MICRORNA MIRNA BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
| 0.0 | 0.6 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.0 | 1.3 | REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 | Genes involved in CDK-mediated phosphorylation and removal of Cdc6 |
| 0.0 | 2.1 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.0 | 0.8 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 0.2 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.0 | 0.7 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.0 | 0.9 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 0.9 | REACTOME METABOLISM OF CARBOHYDRATES | Genes involved in Metabolism of carbohydrates |