Project
avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for DLX1_HOXA3_BARX2
Z-value: 0.29
Motif logo
Transcription factors associated with DLX1_HOXA3_BARX2
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
DLX1
|
ENSG00000144355.15 | DLX1 |
|
HOXA3
|
ENSG00000105997.23 | HOXA3 |
|
BARX2
|
ENSG00000043039.7 | BARX2 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| BARX2 | hg38_v1_chr11_+_129375841_129375863 | 0.26 | 1.2e-04 | Click! |
| HOXA3 | hg38_v1_chr7_-_27140195_27140221 | 0.24 | 3.6e-04 | Click! |
Activity profile of DLX1_HOXA3_BARX2 motif
Sorted Z-values of DLX1_HOXA3_BARX2 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of DLX1_HOXA3_BARX2
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.7 | 14.0 | GO:2000863 | positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866) |
| 2.2 | 22.1 | GO:0006537 | glutamate biosynthetic process(GO:0006537) |
| 1.9 | 5.6 | GO:1905246 | regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246) |
| 1.7 | 5.0 | GO:0070105 | positive regulation of interleukin-6-mediated signaling pathway(GO:0070105) |
| 1.6 | 4.8 | GO:0072709 | cellular response to sorbitol(GO:0072709) |
| 1.2 | 3.7 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
| 1.2 | 14.5 | GO:0051581 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 1.1 | 3.2 | GO:1990168 | protein K33-linked deubiquitination(GO:1990168) |
| 1.0 | 2.9 | GO:0034769 | basement membrane disassembly(GO:0034769) |
| 0.9 | 3.5 | GO:1990414 | replication-born double-strand break repair via sister chromatid exchange(GO:1990414) |
| 0.8 | 5.0 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
| 0.7 | 7.2 | GO:0036309 | protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) |
| 0.7 | 8.6 | GO:0098712 | L-glutamate import across plasma membrane(GO:0098712) |
| 0.6 | 4.5 | GO:0048241 | epinephrine transport(GO:0048241) |
| 0.6 | 2.5 | GO:0010430 | fatty acid omega-oxidation(GO:0010430) |
| 0.6 | 2.9 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
| 0.6 | 1.7 | GO:0061026 | cardiac muscle tissue regeneration(GO:0061026) |
| 0.6 | 11.3 | GO:0006068 | ethanol catabolic process(GO:0006068) |
| 0.5 | 1.1 | GO:0071879 | positive regulation of adrenergic receptor signaling pathway(GO:0071879) |
| 0.5 | 1.6 | GO:1904844 | response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845) |
| 0.5 | 3.2 | GO:0061743 | motor learning(GO:0061743) |
| 0.5 | 1.5 | GO:0032661 | regulation of interleukin-18 production(GO:0032661) |
| 0.5 | 1.4 | GO:0002503 | peptide antigen assembly with MHC class II protein complex(GO:0002503) |
| 0.5 | 1.4 | GO:0061713 | neural crest cell migration involved in heart formation(GO:0003147) cell migration involved in heart formation(GO:0060974) anterior neural tube closure(GO:0061713) |
| 0.5 | 1.8 | GO:0071418 | cellular response to amine stimulus(GO:0071418) |
| 0.4 | 1.3 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) |
| 0.4 | 1.3 | GO:0035928 | miRNA catabolic process(GO:0010587) rRNA import into mitochondrion(GO:0035928) |
| 0.4 | 10.1 | GO:0009756 | carbohydrate mediated signaling(GO:0009756) |
| 0.4 | 3.5 | GO:0090063 | positive regulation of microtubule nucleation(GO:0090063) |
| 0.4 | 3.1 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 0.4 | 2.5 | GO:0033133 | positive regulation of glucokinase activity(GO:0033133) |
| 0.4 | 1.3 | GO:0015860 | purine nucleoside transmembrane transport(GO:0015860) |
| 0.4 | 2.9 | GO:0070562 | regulation of vitamin D receptor signaling pathway(GO:0070562) |
| 0.4 | 5.3 | GO:0042908 | xenobiotic transport(GO:0042908) |
| 0.4 | 1.6 | GO:0019355 | nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628) |
| 0.4 | 2.7 | GO:1904879 | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879) |
| 0.4 | 1.2 | GO:0015722 | canalicular bile acid transport(GO:0015722) |
| 0.4 | 2.2 | GO:0007296 | vitellogenesis(GO:0007296) |
| 0.4 | 0.4 | GO:1990167 | protein K27-linked deubiquitination(GO:1990167) |
| 0.3 | 2.4 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.3 | 6.9 | GO:0007016 | cytoskeletal anchoring at plasma membrane(GO:0007016) |
| 0.3 | 4.6 | GO:0048245 | eosinophil chemotaxis(GO:0048245) |
| 0.3 | 1.3 | GO:0051697 | protein delipidation(GO:0051697) |
| 0.3 | 26.9 | GO:2000649 | regulation of sodium ion transmembrane transporter activity(GO:2000649) |
| 0.3 | 2.3 | GO:0032097 | positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) |
| 0.3 | 12.6 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 0.3 | 1.5 | GO:0018352 | protein-pyridoxal-5-phosphate linkage(GO:0018352) |
| 0.3 | 1.2 | GO:0060160 | negative regulation of dopamine receptor signaling pathway(GO:0060160) |
| 0.3 | 1.8 | GO:0010746 | regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748) |
| 0.3 | 1.1 | GO:0010836 | negative regulation of protein ADP-ribosylation(GO:0010836) |
| 0.3 | 2.5 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.3 | 1.9 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.3 | 0.5 | GO:0098989 | NMDA selective glutamate receptor signaling pathway(GO:0098989) |
| 0.3 | 2.4 | GO:0061669 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
| 0.3 | 0.8 | GO:0000706 | meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918) |
| 0.3 | 5.6 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.3 | 0.8 | GO:0060474 | positive regulation of sperm motility involved in capacitation(GO:0060474) |
| 0.2 | 14.6 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.2 | 0.7 | GO:0035470 | positive regulation of vascular wound healing(GO:0035470) |
| 0.2 | 0.5 | GO:0042495 | detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340) |
| 0.2 | 1.2 | GO:0007386 | compartment pattern specification(GO:0007386) |
| 0.2 | 1.4 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.2 | 2.1 | GO:0030807 | positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) |
| 0.2 | 0.7 | GO:0046603 | negative regulation of mitotic centrosome separation(GO:0046603) |
| 0.2 | 1.4 | GO:0001920 | negative regulation of receptor recycling(GO:0001920) |
| 0.2 | 2.7 | GO:0098719 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.2 | 0.7 | GO:0009720 | detection of hormone stimulus(GO:0009720) |
| 0.2 | 0.9 | GO:0008628 | hormone-mediated apoptotic signaling pathway(GO:0008628) positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158) |
| 0.2 | 0.9 | GO:0070309 | lens fiber cell morphogenesis(GO:0070309) |
| 0.2 | 1.1 | GO:0070433 | negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) positive regulation of protein K63-linked ubiquitination(GO:1902523) |
| 0.2 | 1.7 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 0.2 | 1.5 | GO:0044245 | polysaccharide digestion(GO:0044245) |
| 0.2 | 0.6 | GO:1904908 | negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908) |
| 0.2 | 20.7 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.2 | 1.0 | GO:2000330 | positive regulation of T-helper 17 cell lineage commitment(GO:2000330) |
| 0.2 | 4.7 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.2 | 0.8 | GO:0035359 | negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) |
| 0.2 | 1.3 | GO:0016098 | monoterpenoid metabolic process(GO:0016098) |
| 0.2 | 1.1 | GO:0033625 | positive regulation of integrin activation(GO:0033625) |
| 0.2 | 0.9 | GO:0051835 | positive regulation of synapse structural plasticity(GO:0051835) |
| 0.2 | 1.5 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.2 | 0.5 | GO:0002668 | negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017) |
| 0.2 | 0.5 | GO:0072365 | regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365) |
| 0.2 | 1.9 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.2 | 0.5 | GO:0044752 | response to human chorionic gonadotropin(GO:0044752) cellular response to thyroxine stimulus(GO:0097069) cellular response to L-phenylalanine derivative(GO:1904387) |
| 0.2 | 7.9 | GO:0019433 | triglyceride catabolic process(GO:0019433) |
| 0.2 | 2.5 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 0.2 | 1.0 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 0.2 | 1.3 | GO:0060087 | relaxation of vascular smooth muscle(GO:0060087) |
| 0.2 | 1.1 | GO:0051013 | microtubule severing(GO:0051013) |
| 0.2 | 0.8 | GO:0014809 | regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809) |
| 0.1 | 5.2 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.1 | 0.9 | GO:0018095 | protein polyglutamylation(GO:0018095) |
| 0.1 | 0.4 | GO:0042427 | serotonin biosynthetic process(GO:0042427) |
| 0.1 | 1.2 | GO:2000660 | negative regulation of interleukin-1-mediated signaling pathway(GO:2000660) |
| 0.1 | 2.6 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
| 0.1 | 4.8 | GO:0007608 | sensory perception of smell(GO:0007608) |
| 0.1 | 2.4 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.1 | 1.6 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.1 | 0.3 | GO:1990418 | response to insulin-like growth factor stimulus(GO:1990418) |
| 0.1 | 1.7 | GO:0048743 | positive regulation of skeletal muscle fiber development(GO:0048743) |
| 0.1 | 0.8 | GO:1902857 | positive regulation of nonmotile primary cilium assembly(GO:1902857) |
| 0.1 | 1.2 | GO:1902109 | negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109) |
| 0.1 | 0.4 | GO:0099526 | presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526) |
| 0.1 | 0.8 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
| 0.1 | 0.9 | GO:2000389 | regulation of neutrophil extravasation(GO:2000389) |
| 0.1 | 2.5 | GO:0071447 | cellular response to hydroperoxide(GO:0071447) |
| 0.1 | 0.4 | GO:0061011 | hepatic duct development(GO:0061011) |
| 0.1 | 0.3 | GO:2001180 | negative regulation of interleukin-10 secretion(GO:2001180) |
| 0.1 | 0.9 | GO:1902231 | positive regulation of keratinocyte apoptotic process(GO:1902174) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
| 0.1 | 1.1 | GO:2001106 | regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106) |
| 0.1 | 7.6 | GO:0046677 | response to antibiotic(GO:0046677) |
| 0.1 | 8.7 | GO:0007032 | endosome organization(GO:0007032) |
| 0.1 | 1.1 | GO:0045329 | carnitine biosynthetic process(GO:0045329) |
| 0.1 | 4.2 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
| 0.1 | 0.2 | GO:1902358 | sulfate transmembrane transport(GO:1902358) |
| 0.1 | 1.0 | GO:0042355 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.1 | 1.8 | GO:0006828 | manganese ion transport(GO:0006828) |
| 0.1 | 3.3 | GO:0051491 | positive regulation of filopodium assembly(GO:0051491) |
| 0.1 | 5.0 | GO:0050435 | membrane protein ectodomain proteolysis(GO:0006509) beta-amyloid metabolic process(GO:0050435) |
| 0.1 | 1.2 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
| 0.1 | 0.8 | GO:0006572 | tyrosine catabolic process(GO:0006572) |
| 0.1 | 3.5 | GO:0007194 | negative regulation of adenylate cyclase activity(GO:0007194) |
| 0.1 | 0.9 | GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) |
| 0.1 | 2.1 | GO:0055003 | cardiac myofibril assembly(GO:0055003) |
| 0.1 | 0.2 | GO:0060369 | positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) |
| 0.1 | 4.0 | GO:1900740 | regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740) |
| 0.1 | 2.0 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.1 | 6.3 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.1 | 1.5 | GO:0043484 | regulation of RNA splicing(GO:0043484) |
| 0.1 | 1.3 | GO:0035878 | nail development(GO:0035878) |
| 0.1 | 0.3 | GO:0071918 | urea transmembrane transport(GO:0071918) |
| 0.1 | 2.2 | GO:2000001 | regulation of DNA damage checkpoint(GO:2000001) |
| 0.1 | 0.3 | GO:0030035 | microspike assembly(GO:0030035) |
| 0.1 | 0.5 | GO:0046092 | deoxycytidine metabolic process(GO:0046092) |
| 0.1 | 1.0 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.1 | 0.5 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.1 | 1.4 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 0.1 | 5.0 | GO:0050798 | activated T cell proliferation(GO:0050798) |
| 0.1 | 0.3 | GO:0090086 | negative regulation of protein deubiquitination(GO:0090086) |
| 0.1 | 0.5 | GO:0007468 | regulation of rhodopsin gene expression(GO:0007468) |
| 0.1 | 2.5 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.1 | 0.5 | GO:0032218 | riboflavin transport(GO:0032218) |
| 0.1 | 1.1 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.1 | 0.4 | GO:0009213 | pyrimidine nucleoside triphosphate catabolic process(GO:0009149) pyrimidine deoxyribonucleoside triphosphate catabolic process(GO:0009213) |
| 0.1 | 2.8 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
| 0.1 | 0.3 | GO:0042320 | regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) |
| 0.1 | 1.0 | GO:2000311 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311) |
| 0.1 | 0.2 | GO:2000296 | regulation of hydrogen peroxide catabolic process(GO:2000295) negative regulation of hydrogen peroxide catabolic process(GO:2000296) |
| 0.1 | 0.7 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.1 | 0.3 | GO:0008582 | regulation of synaptic growth at neuromuscular junction(GO:0008582) |
| 0.1 | 0.4 | GO:0061107 | seminal vesicle development(GO:0061107) |
| 0.1 | 2.0 | GO:0035640 | exploration behavior(GO:0035640) |
| 0.1 | 0.6 | GO:0045725 | positive regulation of glycogen biosynthetic process(GO:0045725) |
| 0.1 | 0.4 | GO:0032202 | telomere assembly(GO:0032202) |
| 0.1 | 0.2 | GO:0098582 | innate vocalization behavior(GO:0098582) |
| 0.1 | 0.3 | GO:0021965 | spinal cord ventral commissure morphogenesis(GO:0021965) |
| 0.1 | 4.8 | GO:1902600 | hydrogen ion transmembrane transport(GO:1902600) |
| 0.1 | 0.5 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 0.1 | 0.5 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 0.1 | 2.8 | GO:0002820 | negative regulation of adaptive immune response(GO:0002820) |
| 0.1 | 1.5 | GO:0014046 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
| 0.1 | 0.4 | GO:0031998 | regulation of fatty acid beta-oxidation(GO:0031998) |
| 0.1 | 10.0 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.1 | 1.1 | GO:0035728 | response to hepatocyte growth factor(GO:0035728) |
| 0.1 | 0.1 | GO:0070837 | dehydroascorbic acid transport(GO:0070837) |
| 0.1 | 0.4 | GO:1990592 | protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592) |
| 0.1 | 2.7 | GO:0007040 | lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171) |
| 0.1 | 0.2 | GO:0010989 | negative regulation of low-density lipoprotein particle clearance(GO:0010989) |
| 0.1 | 0.5 | GO:0045741 | positive regulation of epidermal growth factor-activated receptor activity(GO:0045741) |
| 0.1 | 0.2 | GO:0002730 | regulation of dendritic cell cytokine production(GO:0002730) positive regulation of interferon-alpha biosynthetic process(GO:0045356) |
| 0.1 | 0.2 | GO:0072101 | heart induction(GO:0003129) BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134) apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) negative regulation of branching involved in ureteric bud morphogenesis(GO:0090191) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007) |
| 0.1 | 0.4 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
| 0.0 | 0.1 | GO:0045359 | dendritic cell proliferation(GO:0044565) positive regulation of interferon-beta biosynthetic process(GO:0045359) |
| 0.0 | 4.2 | GO:0000070 | mitotic sister chromatid segregation(GO:0000070) |
| 0.0 | 1.2 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.0 | 0.2 | GO:1902725 | negative regulation of satellite cell differentiation(GO:1902725) |
| 0.0 | 27.2 | GO:0006397 | mRNA processing(GO:0006397) |
| 0.0 | 0.3 | GO:1902714 | negative regulation of interferon-gamma secretion(GO:1902714) |
| 0.0 | 18.7 | GO:0051056 | regulation of small GTPase mediated signal transduction(GO:0051056) |
| 0.0 | 0.3 | GO:0055059 | asymmetric neuroblast division(GO:0055059) |
| 0.0 | 3.1 | GO:0035690 | cellular response to drug(GO:0035690) |
| 0.0 | 1.2 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.0 | 0.2 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 0.0 | 0.4 | GO:0048007 | antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007) |
| 0.0 | 0.6 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 0.0 | 1.0 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.0 | 0.4 | GO:2001300 | lipoxin metabolic process(GO:2001300) |
| 0.0 | 4.1 | GO:0051225 | spindle assembly(GO:0051225) |
| 0.0 | 1.5 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.0 | 0.2 | GO:0000160 | phosphorelay signal transduction system(GO:0000160) |
| 0.0 | 0.6 | GO:0045898 | regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898) |
| 0.0 | 1.5 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
| 0.0 | 0.4 | GO:0060122 | inner ear receptor stereocilium organization(GO:0060122) |
| 0.0 | 0.2 | GO:1990253 | cellular response to leucine starvation(GO:1990253) |
| 0.0 | 0.1 | GO:0006550 | isoleucine metabolic process(GO:0006549) isoleucine catabolic process(GO:0006550) |
| 0.0 | 0.2 | GO:0051791 | medium-chain fatty acid metabolic process(GO:0051791) |
| 0.0 | 0.8 | GO:0000291 | nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.0 | 1.1 | GO:0035196 | production of miRNAs involved in gene silencing by miRNA(GO:0035196) |
| 0.0 | 0.1 | GO:0044557 | relaxation of smooth muscle(GO:0044557) sodium ion import(GO:0097369) |
| 0.0 | 0.2 | GO:0045416 | positive regulation of interleukin-8 biosynthetic process(GO:0045416) |
| 0.0 | 1.0 | GO:1903959 | regulation of anion transmembrane transport(GO:1903959) |
| 0.0 | 0.2 | GO:0001782 | B cell homeostasis(GO:0001782) |
| 0.0 | 0.3 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
| 0.0 | 0.1 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
| 0.0 | 2.2 | GO:0090630 | activation of GTPase activity(GO:0090630) |
| 0.0 | 2.5 | GO:0097194 | execution phase of apoptosis(GO:0097194) |
| 0.0 | 0.5 | GO:0008211 | glucocorticoid metabolic process(GO:0008211) |
| 0.0 | 1.1 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
| 0.0 | 0.3 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.0 | 0.4 | GO:0046069 | cGMP catabolic process(GO:0046069) |
| 0.0 | 0.4 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 0.0 | 0.6 | GO:0035872 | nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) |
| 0.0 | 0.3 | GO:0016446 | somatic hypermutation of immunoglobulin genes(GO:0016446) |
| 0.0 | 1.5 | GO:0000045 | autophagosome assembly(GO:0000045) |
| 0.0 | 0.5 | GO:0008380 | RNA splicing(GO:0008380) |
| 0.0 | 0.4 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
| 0.0 | 0.2 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 0.0 | 0.3 | GO:0015884 | folic acid transport(GO:0015884) |
| 0.0 | 0.1 | GO:0044341 | sodium-dependent phosphate transport(GO:0044341) |
| 0.0 | 0.1 | GO:0097242 | beta-amyloid clearance(GO:0097242) |
| 0.0 | 0.7 | GO:0006809 | nitric oxide biosynthetic process(GO:0006809) |
| 0.0 | 0.1 | GO:0009249 | protein lipoylation(GO:0009249) |
| 0.0 | 0.8 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.0 | 0.5 | GO:0007257 | activation of JUN kinase activity(GO:0007257) |
| 0.0 | 1.4 | GO:0030819 | positive regulation of cAMP biosynthetic process(GO:0030819) |
| 0.0 | 0.7 | GO:0060338 | regulation of type I interferon-mediated signaling pathway(GO:0060338) |
| 0.0 | 0.8 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.0 | 0.1 | GO:0050955 | thermoception(GO:0050955) |
| 0.0 | 0.2 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
| 0.0 | 15.3 | GO:0007417 | central nervous system development(GO:0007417) |
| 0.0 | 0.9 | GO:0038083 | peptidyl-tyrosine autophosphorylation(GO:0038083) |
| 0.0 | 0.2 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.0 | 0.1 | GO:0098856 | intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856) |
| 0.0 | 0.3 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.0 | 1.1 | GO:0008286 | insulin receptor signaling pathway(GO:0008286) |
| 0.0 | 0.3 | GO:0032642 | regulation of chemokine production(GO:0032642) |
| 0.0 | 0.2 | GO:0032196 | transposition(GO:0032196) |
| 0.0 | 0.1 | GO:0006552 | leucine catabolic process(GO:0006552) |
| 0.0 | 0.2 | GO:0034204 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.0 | 0.2 | GO:0045599 | negative regulation of fat cell differentiation(GO:0045599) |
| 0.0 | 1.0 | GO:0043433 | negative regulation of sequence-specific DNA binding transcription factor activity(GO:0043433) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 12.9 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 1.7 | 5.0 | GO:0070931 | Golgi-associated vesicle lumen(GO:0070931) |
| 0.6 | 5.8 | GO:0070652 | HAUS complex(GO:0070652) |
| 0.6 | 2.8 | GO:0005726 | perichromatin fibrils(GO:0005726) |
| 0.6 | 3.3 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
| 0.4 | 2.2 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.4 | 2.9 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.3 | 10.8 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.3 | 1.2 | GO:0070876 | SOSS complex(GO:0070876) |
| 0.3 | 4.8 | GO:0045277 | respiratory chain complex IV(GO:0045277) |
| 0.3 | 5.6 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.3 | 0.5 | GO:0043159 | acrosomal matrix(GO:0043159) |
| 0.2 | 5.0 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 0.2 | 2.0 | GO:0097504 | Gemini of coiled bodies(GO:0097504) |
| 0.2 | 0.9 | GO:0016013 | syntrophin complex(GO:0016013) |
| 0.2 | 4.6 | GO:0031045 | dense core granule(GO:0031045) |
| 0.2 | 4.2 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.2 | 0.6 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 0.2 | 4.6 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.2 | 1.5 | GO:0070187 | telosome(GO:0070187) |
| 0.2 | 7.5 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.2 | 2.4 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.2 | 0.5 | GO:0017109 | glutamate-cysteine ligase complex(GO:0017109) |
| 0.2 | 0.5 | GO:0072536 | interleukin-23 receptor complex(GO:0072536) |
| 0.2 | 0.5 | GO:0035354 | Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354) |
| 0.2 | 1.7 | GO:0005955 | calcineurin complex(GO:0005955) |
| 0.2 | 0.6 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 0.2 | 0.6 | GO:0044307 | dendritic branch(GO:0044307) |
| 0.2 | 2.4 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.1 | 7.0 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 2.2 | GO:0097433 | dense body(GO:0097433) |
| 0.1 | 2.7 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.1 | 35.5 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.1 | 0.7 | GO:0031205 | endoplasmic reticulum Sec complex(GO:0031205) |
| 0.1 | 0.4 | GO:0048788 | cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569) |
| 0.1 | 0.9 | GO:0014701 | junctional sarcoplasmic reticulum membrane(GO:0014701) |
| 0.1 | 3.9 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.1 | 0.8 | GO:0014802 | terminal cisterna(GO:0014802) |
| 0.1 | 1.3 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.1 | 0.4 | GO:0036027 | protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183) |
| 0.1 | 6.9 | GO:0043034 | costamere(GO:0043034) |
| 0.1 | 2.8 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.1 | 1.6 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.1 | 0.9 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 0.1 | 1.0 | GO:0061574 | ASAP complex(GO:0061574) |
| 0.1 | 17.8 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.1 | 0.5 | GO:0070826 | paraferritin complex(GO:0070826) |
| 0.1 | 1.1 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.1 | 1.7 | GO:0097342 | ripoptosome(GO:0097342) |
| 0.1 | 0.2 | GO:0000805 | X chromosome(GO:0000805) |
| 0.1 | 0.8 | GO:0000778 | condensed nuclear chromosome kinetochore(GO:0000778) |
| 0.1 | 1.6 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.1 | 1.4 | GO:0031362 | anchored component of external side of plasma membrane(GO:0031362) |
| 0.1 | 1.4 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 0.1 | 0.5 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 0.1 | 1.1 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.1 | 1.2 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.1 | 0.8 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
| 0.1 | 2.4 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 0.1 | 0.7 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.1 | 0.2 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.1 | 0.4 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
| 0.1 | 1.5 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.0 | 1.0 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
| 0.0 | 1.9 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 2.6 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.0 | 0.8 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.0 | 0.8 | GO:0036038 | MKS complex(GO:0036038) |
| 0.0 | 1.2 | GO:0032809 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 0.0 | 0.6 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 0.0 | 3.4 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 5.5 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 13.4 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 11.0 | GO:0005765 | lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852) |
| 0.0 | 1.4 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.0 | 1.0 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.0 | 0.2 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.0 | 0.2 | GO:0034448 | EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131) |
| 0.0 | 2.3 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 63.1 | GO:0031226 | intrinsic component of plasma membrane(GO:0031226) |
| 0.0 | 0.4 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.0 | 0.5 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 1.7 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.0 | 1.8 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 2.0 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 0.7 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
| 0.0 | 0.8 | GO:0060170 | ciliary membrane(GO:0060170) |
| 0.0 | 0.1 | GO:0090543 | Flemming body(GO:0090543) |
| 0.0 | 0.4 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 1.0 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.3 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.0 | 0.3 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.0 | 0.7 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 1.7 | GO:0005814 | centriole(GO:0005814) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.6 | 12.9 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 1.9 | 11.3 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) |
| 1.9 | 26.2 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 1.4 | 8.6 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
| 1.3 | 5.0 | GO:0008798 | beta-aspartyl-peptidase activity(GO:0008798) |
| 1.2 | 11.7 | GO:0004064 | arylesterase activity(GO:0004064) |
| 1.1 | 4.5 | GO:0008513 | acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375) |
| 1.1 | 5.5 | GO:0015562 | efflux transmembrane transporter activity(GO:0015562) |
| 1.1 | 3.2 | GO:1904455 | ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455) |
| 1.0 | 5.0 | GO:0047273 | galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273) |
| 0.6 | 2.5 | GO:0004031 | aldehyde oxidase activity(GO:0004031) ethanol binding(GO:0035276) |
| 0.6 | 3.5 | GO:0009378 | four-way junction helicase activity(GO:0009378) |
| 0.6 | 2.9 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 0.6 | 0.6 | GO:0005350 | pyrimidine nucleobase transmembrane transporter activity(GO:0005350) |
| 0.6 | 23.3 | GO:0017091 | AU-rich element binding(GO:0017091) |
| 0.5 | 3.1 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 0.5 | 2.8 | GO:0004359 | glutaminase activity(GO:0004359) |
| 0.5 | 1.8 | GO:0004852 | uroporphyrinogen-III synthase activity(GO:0004852) |
| 0.4 | 4.7 | GO:0033038 | bitter taste receptor activity(GO:0033038) |
| 0.4 | 2.5 | GO:0003873 | 6-phosphofructo-2-kinase activity(GO:0003873) |
| 0.4 | 26.5 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 0.4 | 1.6 | GO:0000309 | nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) |
| 0.4 | 1.1 | GO:0008336 | gamma-butyrobetaine dioxygenase activity(GO:0008336) |
| 0.4 | 1.8 | GO:0030197 | extracellular matrix constituent, lubricant activity(GO:0030197) |
| 0.4 | 3.5 | GO:0005549 | odorant binding(GO:0005549) |
| 0.4 | 1.4 | GO:0061714 | folic acid receptor activity(GO:0061714) |
| 0.3 | 5.6 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.3 | 1.7 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 0.3 | 2.9 | GO:0034056 | estrogen response element binding(GO:0034056) |
| 0.3 | 1.3 | GO:0005415 | nucleoside:sodium symporter activity(GO:0005415) |
| 0.3 | 2.5 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 0.3 | 8.8 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.3 | 0.9 | GO:0090555 | phosphatidylethanolamine-translocating ATPase activity(GO:0090555) |
| 0.3 | 1.2 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.3 | 1.5 | GO:0004558 | alpha-1,4-glucosidase activity(GO:0004558) |
| 0.3 | 1.7 | GO:0097199 | cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199) |
| 0.3 | 2.7 | GO:0015385 | sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.3 | 0.8 | GO:0003918 | DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505) |
| 0.3 | 1.3 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
| 0.2 | 1.2 | GO:0023024 | MHC class I protein complex binding(GO:0023024) |
| 0.2 | 0.7 | GO:0042806 | fucose binding(GO:0042806) |
| 0.2 | 0.7 | GO:0005260 | channel-conductance-controlling ATPase activity(GO:0005260) |
| 0.2 | 1.3 | GO:0034046 | poly(G) binding(GO:0034046) |
| 0.2 | 1.7 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 0.2 | 1.9 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.2 | 2.7 | GO:0086056 | voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056) |
| 0.2 | 0.6 | GO:0015616 | DNA translocase activity(GO:0015616) |
| 0.2 | 3.3 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.2 | 2.2 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.2 | 0.6 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.2 | 0.8 | GO:0035473 | lipase binding(GO:0035473) |
| 0.2 | 17.2 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.2 | 0.7 | GO:0008281 | sulfonylurea receptor activity(GO:0008281) |
| 0.2 | 1.6 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.2 | 0.5 | GO:0004357 | glutamate-cysteine ligase activity(GO:0004357) |
| 0.2 | 0.7 | GO:0034041 | sterol-transporting ATPase activity(GO:0034041) |
| 0.2 | 0.5 | GO:0042019 | interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020) |
| 0.2 | 4.8 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.2 | 0.7 | GO:0016434 | rRNA (cytosine) methyltransferase activity(GO:0016434) |
| 0.2 | 0.5 | GO:0035663 | Toll-like receptor 2 binding(GO:0035663) |
| 0.2 | 5.9 | GO:0004708 | MAP kinase kinase activity(GO:0004708) |
| 0.2 | 1.1 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 0.2 | 0.5 | GO:0005143 | interleukin-12 receptor binding(GO:0005143) |
| 0.2 | 2.1 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.2 | 1.4 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.1 | 0.9 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.1 | 4.6 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.1 | 0.4 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
| 0.1 | 3.7 | GO:0071949 | FAD binding(GO:0071949) |
| 0.1 | 2.5 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.1 | 0.8 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 0.1 | 6.4 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.1 | 10.6 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.1 | 1.1 | GO:0004117 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) |
| 0.1 | 4.1 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 0.1 | 1.6 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.1 | 1.7 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.1 | 1.3 | GO:0030169 | low-density lipoprotein particle binding(GO:0030169) |
| 0.1 | 27.6 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.1 | 4.2 | GO:0042056 | chemoattractant activity(GO:0042056) |
| 0.1 | 0.3 | GO:0033878 | hormone-sensitive lipase activity(GO:0033878) |
| 0.1 | 3.3 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.1 | 0.8 | GO:0019237 | centromeric DNA binding(GO:0019237) |
| 0.1 | 8.6 | GO:0004722 | protein serine/threonine phosphatase activity(GO:0004722) |
| 0.1 | 0.7 | GO:0008271 | secondary active sulfate transmembrane transporter activity(GO:0008271) |
| 0.1 | 0.5 | GO:0015639 | cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
| 0.1 | 3.5 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.1 | 3.5 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.1 | 1.1 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.1 | 0.3 | GO:0090554 | phosphatidylcholine-translocating ATPase activity(GO:0090554) |
| 0.1 | 0.3 | GO:0005042 | netrin receptor activity(GO:0005042) |
| 0.1 | 0.3 | GO:0015204 | urea transmembrane transporter activity(GO:0015204) |
| 0.1 | 5.2 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.1 | 1.6 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
| 0.1 | 1.4 | GO:0005068 | transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) |
| 0.1 | 0.6 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.1 | 1.3 | GO:0001608 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.1 | 1.5 | GO:0008391 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.1 | 0.5 | GO:0032217 | riboflavin transporter activity(GO:0032217) |
| 0.1 | 0.2 | GO:0008502 | melatonin receptor activity(GO:0008502) |
| 0.1 | 1.1 | GO:0019957 | C-C chemokine binding(GO:0019957) |
| 0.1 | 5.0 | GO:0051018 | protein kinase A binding(GO:0051018) |
| 0.1 | 0.8 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.1 | 0.5 | GO:0004137 | deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797) |
| 0.1 | 1.5 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.1 | 0.3 | GO:0051998 | carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998) |
| 0.1 | 0.2 | GO:0070290 | N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.1 | 0.3 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.1 | 1.0 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.1 | 0.7 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.1 | 1.0 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
| 0.1 | 1.1 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.1 | 0.4 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
| 0.1 | 0.8 | GO:0022851 | GABA-gated chloride ion channel activity(GO:0022851) |
| 0.1 | 2.4 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.1 | 1.7 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.1 | 13.3 | GO:0035091 | phosphatidylinositol binding(GO:0035091) |
| 0.1 | 2.0 | GO:0008200 | ion channel inhibitor activity(GO:0008200) |
| 0.1 | 1.2 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.1 | 0.3 | GO:0035252 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
| 0.1 | 1.4 | GO:0023026 | MHC class II protein complex binding(GO:0023026) |
| 0.1 | 6.6 | GO:0035591 | signaling adaptor activity(GO:0035591) |
| 0.1 | 0.3 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.1 | 0.3 | GO:0005152 | interleukin-1 receptor antagonist activity(GO:0005152) |
| 0.1 | 0.4 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.1 | 1.5 | GO:0042166 | acetylcholine binding(GO:0042166) |
| 0.1 | 0.2 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
| 0.0 | 0.5 | GO:0008430 | selenium binding(GO:0008430) |
| 0.0 | 0.2 | GO:0047374 | methylumbelliferyl-acetate deacetylase activity(GO:0047374) |
| 0.0 | 0.4 | GO:0030883 | lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884) |
| 0.0 | 1.2 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.0 | 0.4 | GO:0032552 | deoxyribonucleotide binding(GO:0032552) |
| 0.0 | 0.9 | GO:0048018 | receptor agonist activity(GO:0048018) |
| 0.0 | 1.5 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 4.8 | GO:0005262 | calcium channel activity(GO:0005262) |
| 0.0 | 1.0 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 0.4 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.0 | 0.5 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.0 | 0.7 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
| 0.0 | 1.2 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
| 0.0 | 0.4 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.0 | 0.7 | GO:0005522 | profilin binding(GO:0005522) |
| 0.0 | 0.1 | GO:0033300 | dehydroascorbic acid transporter activity(GO:0033300) |
| 0.0 | 0.2 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 0.0 | 0.5 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 0.0 | 0.8 | GO:0002162 | dystroglycan binding(GO:0002162) |
| 0.0 | 0.9 | GO:0097200 | cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200) |
| 0.0 | 2.0 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 7.1 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.0 | 0.8 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.0 | 1.5 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 0.1 | GO:0003960 | NADPH:quinone reductase activity(GO:0003960) |
| 0.0 | 5.0 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.0 | 2.9 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.0 | 1.2 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 1.2 | GO:0050780 | dopamine receptor binding(GO:0050780) |
| 0.0 | 0.7 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.0 | 3.1 | GO:0003774 | motor activity(GO:0003774) |
| 0.0 | 0.2 | GO:0004465 | lipoprotein lipase activity(GO:0004465) |
| 0.0 | 0.4 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.0 | 0.1 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 0.0 | 0.5 | GO:0005112 | Notch binding(GO:0005112) |
| 0.0 | 1.1 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.0 | 0.1 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.0 | 6.4 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659) |
| 0.0 | 0.1 | GO:0099580 | ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580) |
| 0.0 | 0.8 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.0 | 0.5 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.0 | 1.1 | GO:0042162 | telomeric DNA binding(GO:0042162) |
| 0.0 | 0.3 | GO:0005542 | folic acid binding(GO:0005542) |
| 0.0 | 0.2 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
| 0.0 | 1.4 | GO:0005254 | chloride channel activity(GO:0005254) |
| 0.0 | 0.5 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.0 | 0.1 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.0 | 0.1 | GO:0004773 | steryl-sulfatase activity(GO:0004773) |
| 0.0 | 2.6 | GO:0101005 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.0 | 0.8 | GO:0004532 | exoribonuclease activity(GO:0004532) |
| 0.0 | 0.4 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.0 | 0.7 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.0 | 5.0 | GO:0003729 | mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822) |
| 0.0 | 0.3 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.0 | 1.6 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.3 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 0.3 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.0 | 0.8 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.0 | 0.5 | GO:0004527 | exonuclease activity(GO:0004527) |
| 0.0 | 0.2 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.5 | GO:0015026 | coreceptor activity(GO:0015026) |
| 0.0 | 3.3 | GO:0001227 | transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 14.0 | PID INTEGRIN A9B1 PATHWAY | Alpha9 beta1 integrin signaling events |
| 0.2 | 4.8 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.1 | 1.5 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.1 | 18.0 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 2.1 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.1 | 10.4 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.1 | 2.8 | SIG IL4RECEPTOR IN B LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.1 | 6.6 | PID TGFBR PATHWAY | TGF-beta receptor signaling |
| 0.1 | 1.2 | PID LPA4 PATHWAY | LPA4-mediated signaling events |
| 0.1 | 2.8 | PID IFNG PATHWAY | IFN-gamma pathway |
| 0.1 | 0.9 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.1 | 4.1 | SIG CHEMOTAXIS | Genes related to chemotaxis |
| 0.1 | 6.0 | ST INTEGRIN SIGNALING PATHWAY | Integrin Signaling Pathway |
| 0.1 | 9.7 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.1 | 2.2 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.1 | 0.8 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
| 0.1 | 4.0 | PID TXA2PATHWAY | Thromboxane A2 receptor signaling |
| 0.1 | 1.5 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.1 | 1.6 | SIG BCR SIGNALING PATHWAY | Members of the BCR signaling pathway |
| 0.1 | 1.7 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
| 0.1 | 0.2 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.1 | 0.4 | ST INTERLEUKIN 4 PATHWAY | Interleukin 4 (IL-4) Pathway |
| 0.1 | 1.4 | PID GMCSF PATHWAY | GMCSF-mediated signaling events |
| 0.0 | 4.3 | PID E2F PATHWAY | E2F transcription factor network |
| 0.0 | 1.6 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 2.0 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.0 | 1.9 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.0 | 1.0 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.0 | 1.5 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.5 | PID GLYPICAN 1PATHWAY | Glypican 1 network |
| 0.0 | 0.5 | PID RETINOIC ACID PATHWAY | Retinoic acid receptors-mediated signaling |
| 0.0 | 0.5 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.0 | 0.5 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.0 | 0.7 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 0.2 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.0 | 0.3 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.0 | 0.3 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 0.3 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 12.3 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.5 | 11.3 | REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES | Genes involved in Cytosolic sulfonation of small molecules |
| 0.5 | 7.7 | REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
| 0.4 | 8.6 | REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
| 0.3 | 27.1 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.3 | 4.8 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.3 | 2.5 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.3 | 2.9 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
| 0.2 | 5.4 | REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.2 | 17.2 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.2 | 1.5 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.1 | 6.1 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 0.1 | 1.8 | REACTOME SIGNAL ATTENUATION | Genes involved in Signal attenuation |
| 0.1 | 1.7 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.1 | 2.1 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 0.1 | 1.2 | REACTOME BETA DEFENSINS | Genes involved in Beta defensins |
| 0.1 | 4.5 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.1 | 4.6 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 4.0 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.1 | 2.8 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.1 | 2.8 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 0.1 | 7.1 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 0.1 | 1.7 | REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 | Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 |
| 0.1 | 1.4 | REACTOME DOWNSTREAM TCR SIGNALING | Genes involved in Downstream TCR signaling |
| 0.1 | 1.2 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.1 | 2.9 | REACTOME SIGNALING BY FGFR1 FUSION MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
| 0.1 | 10.3 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 1.1 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.1 | 1.6 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.1 | 1.5 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.1 | 1.5 | REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS | Genes involved in Presynaptic nicotinic acetylcholine receptors |
| 0.1 | 1.0 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.1 | 1.1 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.1 | 5.9 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.1 | 1.6 | REACTOME PHOSPHORYLATION OF THE APC C | Genes involved in Phosphorylation of the APC/C |
| 0.1 | 2.5 | REACTOME CELL CELL JUNCTION ORGANIZATION | Genes involved in Cell-cell junction organization |
| 0.1 | 1.3 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.1 | 1.7 | REACTOME SHC1 EVENTS IN ERBB4 SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
| 0.1 | 1.8 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.1 | 1.3 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 1.1 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.1 | 1.9 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.1 | 0.8 | REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR | Genes involved in Signaling by constitutively active EGFR |
| 0.1 | 1.0 | REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
| 0.1 | 1.2 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.0 | 2.4 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 0.6 | REACTOME METABOLISM OF NON CODING RNA | Genes involved in Metabolism of non-coding RNA |
| 0.0 | 0.6 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.0 | 4.3 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 2.7 | REACTOME NCAM1 INTERACTIONS | Genes involved in NCAM1 interactions |
| 0.0 | 0.9 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.0 | 0.7 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.0 | 0.5 | REACTOME CTLA4 INHIBITORY SIGNALING | Genes involved in CTLA4 inhibitory signaling |
| 0.0 | 1.6 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.0 | 2.2 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 0.0 | 1.6 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.0 | 1.5 | REACTOME LIGAND GATED ION CHANNEL TRANSPORT | Genes involved in Ligand-gated ion channel transport |
| 0.0 | 0.9 | REACTOME CD28 CO STIMULATION | Genes involved in CD28 co-stimulation |
| 0.0 | 2.1 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.0 | 0.2 | REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.0 | 5.7 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 0.6 | REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL | Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
| 0.0 | 0.5 | REACTOME SIGNALING BY NODAL | Genes involved in Signaling by NODAL |
| 0.0 | 1.7 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.2 | REACTOME DEFENSINS | Genes involved in Defensins |
| 0.0 | 1.4 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 0.7 | REACTOME REGULATION OF IFNA SIGNALING | Genes involved in Regulation of IFNA signaling |
| 0.0 | 1.2 | REACTOME G ALPHA S SIGNALLING EVENTS | Genes involved in G alpha (s) signalling events |
| 0.0 | 1.1 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.2 | REACTOME OPSINS | Genes involved in Opsins |
| 0.0 | 0.3 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.0 | 1.4 | REACTOME MHC CLASS II ANTIGEN PRESENTATION | Genes involved in MHC class II antigen presentation |
| 0.0 | 1.0 | REACTOME TRAFFICKING OF AMPA RECEPTORS | Genes involved in Trafficking of AMPA receptors |
| 0.0 | 0.2 | REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
| 0.0 | 0.4 | REACTOME DAG AND IP3 SIGNALING | Genes involved in DAG and IP3 signaling |
| 0.0 | 0.1 | REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
| 0.0 | 0.3 | REACTOME DARPP 32 EVENTS | Genes involved in DARPP-32 events |
| 0.0 | 0.5 | REACTOME PYRIMIDINE METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.0 | 0.5 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.0 | 0.6 | REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |