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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for DLX4_HOXD8

Z-value: 1.70

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Transcription factors associated with DLX4_HOXD8

Gene Symbol Gene ID Gene Info
ENSG00000108813.11 DLX4
ENSG00000175879.9 HOXD8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DLX4hg38_v1_chr17_+_49969178_499692140.152.6e-02Click!

Activity profile of DLX4_HOXD8 motif

Sorted Z-values of DLX4_HOXD8 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of DLX4_HOXD8

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_90038848 25.96 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr2_+_90100235 20.63 ENST00000492446.1
immunoglobulin kappa variable 1D-16
chr2_-_89100352 18.13 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr8_-_85341705 17.39 ENST00000517618.5
carbonic anhydrase 1
chr2_+_90172802 15.77 ENST00000390277.3
immunoglobulin kappa variable 3D-11
chr2_+_90209873 15.71 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr7_+_142791635 13.92 ENST00000633705.1
T cell receptor beta constant 1
chr2_+_90159840 13.40 ENST00000377032.5
immunoglobulin kappa variable 1D-12
chr2_-_88979016 12.47 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr2_-_89117844 12.40 ENST00000490686.1
immunoglobulin kappa variable 1-17
chr2_+_89851723 12.13 ENST00000429992.2
immunoglobulin kappa variable 2D-40
chr2_+_87338511 12.08 ENST00000421835.2
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr2_-_88857582 12.06 ENST00000390237.2
immunoglobulin kappa constant
chr2_+_90234809 11.62 ENST00000443397.5
immunoglobulin kappa variable 3D-7
chr8_-_85341659 11.55 ENST00000522389.5
carbonic anhydrase 1
chr14_-_106470788 11.36 ENST00000434710.1
immunoglobulin heavy variable 3-43
chr4_-_73988179 10.41 ENST00000296028.4
pro-platelet basic protein
chrX_+_1591590 10.36 ENST00000313871.9
ENST00000381261.8
A-kinase anchoring protein 17A
chr2_-_89213917 9.45 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr2_-_89085787 9.01 ENST00000390252.2
immunoglobulin kappa variable 3-15
chr11_-_60183011 8.64 ENST00000533023.5
ENST00000420732.6
ENST00000528851.6
membrane spanning 4-domains A6A
chr15_+_88635626 8.21 ENST00000379224.10
interferon stimulated exonuclease gene 20
chr1_-_158686700 8.20 ENST00000643759.2
spectrin alpha, erythrocytic 1
chr6_-_32941018 8.07 ENST00000418107.3
major histocompatibility complex, class II, DM beta
chr12_-_14950606 7.49 ENST00000536592.5
Rho GDP dissociation inhibitor beta
chr15_+_75347030 7.43 ENST00000566313.5
ENST00000355059.9
ENST00000568059.1
ENST00000568881.1
nei like DNA glycosylase 1
chr14_-_106593319 7.39 ENST00000390627.3
immunoglobulin heavy variable 3-53
chr7_-_77199808 7.33 ENST00000248598.6
fibrinogen like 2
chr22_+_22711689 7.25 ENST00000390308.2
immunoglobulin lambda variable 3-21
chr6_+_32439866 6.95 ENST00000374982.5
ENST00000395388.7
major histocompatibility complex, class II, DR alpha
chr17_+_69502397 6.86 ENST00000613873.4
ENST00000589647.5
mitogen-activated protein kinase kinase 6
chr11_+_5689780 6.86 ENST00000379965.8
ENST00000454828.5
tripartite motif containing 22
chr2_+_89913982 6.83 ENST00000390265.2
immunoglobulin kappa variable 1D-33
chr2_-_88947820 6.60 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr14_-_106277039 6.40 ENST00000390610.2
immunoglobulin heavy variable 1-24
chr12_+_25052634 6.35 ENST00000548766.5
inositol 1,4,5-triphosphate receptor associated 2
chr2_-_136118142 6.35 ENST00000241393.4
C-X-C motif chemokine receptor 4
chr2_-_89040745 6.25 ENST00000480492.1
immunoglobulin kappa variable 1-12
chr2_+_89884740 6.19 ENST00000509129.1
immunoglobulin kappa variable 1D-37 (non-functional)
chr12_+_25052732 6.15 ENST00000547044.5
inositol 1,4,5-triphosphate receptor associated 2
chr4_-_70666492 6.11 ENST00000254801.9
ENST00000391614.7
joining chain of multimeric IgA and IgM
chr12_-_10130241 6.05 ENST00000353231.9
ENST00000525605.1
C-type lectin domain containing 7A
chr6_+_32741382 5.97 ENST00000374940.4
major histocompatibility complex, class II, DQ alpha 2
chr4_+_40197023 5.96 ENST00000381799.10
ras homolog family member H
chr14_-_106185387 5.91 ENST00000390605.2
immunoglobulin heavy variable 1-18
chr2_-_89143133 5.88 ENST00000492167.1
immunoglobulin kappa variable 3-20
chr4_+_40196907 5.75 ENST00000622175.4
ENST00000619474.4
ENST00000615083.4
ENST00000610353.4
ENST00000614836.1
ras homolog family member H
chr12_+_9827472 5.73 ENST00000617793.4
ENST00000617889.5
ENST00000354855.7
ENST00000279545.7
killer cell lectin like receptor F1
chr1_+_158831323 5.69 ENST00000368141.5
myeloid cell nuclear differentiation antigen
chr3_-_39280021 5.65 ENST00000399220.3
C-X3-C motif chemokine receptor 1
chr1_-_92486916 5.48 ENST00000294702.6
growth factor independent 1 transcriptional repressor
chr2_+_90114838 5.47 ENST00000417279.3
immunoglobulin kappa variable 3D-15
chr11_-_60183191 5.41 ENST00000412309.6
membrane spanning 4-domains A6A
chr10_+_7703340 5.39 ENST00000429820.5
ENST00000379587.4
inter-alpha-trypsin inhibitor heavy chain 2
chr12_-_10130143 5.37 ENST00000298523.9
ENST00000396484.6
ENST00000310002.4
ENST00000304084.13
C-type lectin domain containing 7A
chr2_+_90069662 5.36 ENST00000390271.2
immunoglobulin kappa variable 6D-41 (non-functional)
chr5_+_157269317 5.26 ENST00000618329.4
cytoplasmic FMR1 interacting protein 2
chr4_-_99435134 5.26 ENST00000476959.5
ENST00000482593.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr14_-_106269133 5.12 ENST00000390609.3
immunoglobulin heavy variable 3-23
chr6_+_29301701 5.08 ENST00000641895.1
olfactory receptor family 14 subfamily J member 1
chr1_+_198638968 5.07 ENST00000348564.11
ENST00000530727.5
ENST00000442510.8
ENST00000645247.1
ENST00000367367.8
ENST00000367364.5
ENST00000413409.6
protein tyrosine phosphatase receptor type C
chr1_-_183590876 5.06 ENST00000367536.5
neutrophil cytosolic factor 2
chr19_+_49513353 5.00 ENST00000596975.5
Fc fragment of IgG receptor and transporter
chr11_+_56027654 4.85 ENST00000641320.1
olfactory receptor family 5 subfamily AS member 1
chr14_-_106737547 4.79 ENST00000632209.1
immunoglobulin heavy variable 1-69-2
chr17_-_35880350 4.78 ENST00000605140.6
ENST00000651122.1
ENST00000603197.6
C-C motif chemokine ligand 5
chr12_-_7503744 4.75 ENST00000396620.7
ENST00000432237.3
CD163 molecule
chr13_+_50909905 4.68 ENST00000644034.1
ENST00000645955.1
ribonuclease H2 subunit B
chr17_+_36103819 4.61 ENST00000615863.2
ENST00000621626.1
C-C motif chemokine ligand 4
chr14_-_24609660 4.58 ENST00000557220.6
ENST00000216338.9
ENST00000382548.4
granzyme H
chr21_-_14546297 4.51 ENST00000400566.6
ENST00000400564.5
SAM domain, SH3 domain and nuclear localization signals 1
chr16_-_28623560 4.51 ENST00000350842.8
sulfotransferase family 1A member 1
chr16_+_58249910 4.50 ENST00000219299.8
ENST00000443128.6
ENST00000616795.1
coiled-coil domain containing 113
chr7_-_116030750 4.47 ENST00000265440.12
ENST00000320239.11
transcription factor EC
chr2_-_86105839 4.47 ENST00000263857.11
RNA polymerase I subunit A
chr1_+_84181630 4.46 ENST00000610457.1
protein kinase cAMP-activated catalytic subunit beta
chr2_+_88885397 4.46 ENST00000390243.2
immunoglobulin kappa variable 4-1
chr2_+_90021567 4.44 ENST00000436451.2
immunoglobulin kappa variable 6D-21 (non-functional)
chr10_+_7703300 4.43 ENST00000358415.9
inter-alpha-trypsin inhibitor heavy chain 2
chrX_+_37780049 4.43 ENST00000378588.5
cytochrome b-245 beta chain
chr4_-_99435336 4.43 ENST00000437033.7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr7_-_116030735 4.41 ENST00000393485.5
transcription factor EC
chr11_-_5243644 4.41 ENST00000643122.1
hemoglobin subunit delta
chr2_-_89027700 4.41 ENST00000483158.1
immunoglobulin kappa variable 3-11
chr2_-_70248598 4.38 ENST00000445587.5
ENST00000433529.7
ENST00000415783.6
TIA1 cytotoxic granule associated RNA binding protein
chr12_-_11269696 4.37 ENST00000381842.7
proline rich protein BstNI subfamily 3
chr8_-_30812867 4.35 ENST00000518243.5
protein phosphatase 2 catalytic subunit beta
chr18_+_74534594 4.32 ENST00000582365.1
carnosine dipeptidase 1
chr12_+_9669735 4.27 ENST00000545918.5
ENST00000543300.5
ENST00000261339.10
ENST00000466035.6
C-type lectin domain family 2 member D
chr2_+_102418642 4.15 ENST00000264260.6
interleukin 18 receptor accessory protein
chr3_+_46370854 4.15 ENST00000292303.4
C-C motif chemokine receptor 5
chr19_-_54313074 4.12 ENST00000486742.2
ENST00000432233.8
leukocyte immunoglobulin like receptor A5
chr2_-_159798043 4.10 ENST00000664982.1
ENST00000259053.6
novel transcript, sense intronic to CD302and LY75-CD302
CD302 molecule
chr11_-_85665077 4.08 ENST00000527447.2
CREB/ATF bZIP transcription factor
chr3_+_178419123 4.02 ENST00000614557.1
ENST00000455307.5
ENST00000436432.1
potassium large conductance calcium-activated channel, subfamily M, beta member 2 (KCNMB2-IT1 - KCNMB2 readthrough transcript)
long intergenic non-protein coding RNA 1014
chr5_-_135954962 4.01 ENST00000522943.5
ENST00000514447.2
ENST00000274507.6
leukocyte cell derived chemotaxin 2
chr2_+_90220727 4.00 ENST00000471857.2
immunoglobulin kappa variable 1D-8
chr21_-_14546351 4.00 ENST00000619120.4
SAM domain, SH3 domain and nuclear localization signals 1
chr8_+_38728186 3.94 ENST00000519416.5
ENST00000520615.5
transforming acidic coiled-coil containing protein 1
chr4_-_46909206 3.90 ENST00000396533.5
cytochrome c oxidase subunit 7B2
chr4_+_25160631 3.89 ENST00000510415.1
ENST00000507794.2
ENST00000512921.4
SEPSECS antisense RNA 1 (head to head)
phosphatidylinositol 4-kinase type 2 beta
chr7_-_38249572 3.84 ENST00000436911.6
T cell receptor gamma constant 2
chr14_+_20955484 3.80 ENST00000304625.3
ribonuclease A family member 2
chr2_-_157444044 3.78 ENST00000264192.8
cytohesin 1 interacting protein
chr17_+_58238426 3.78 ENST00000421678.6
ENST00000262290.9
ENST00000543544.5
lactoperoxidase
chr2_-_89320146 3.76 ENST00000498574.1
immunoglobulin kappa variable 1-39
chr9_-_21368962 3.75 ENST00000610660.1
interferon alpha 13
chr8_-_33567118 3.74 ENST00000256257.2
ring finger protein 122
chr6_-_52840843 3.74 ENST00000370989.6
glutathione S-transferase alpha 5
chr17_+_36211055 3.73 ENST00000617405.5
ENST00000617416.4
ENST00000613173.4
ENST00000620732.4
ENST00000620098.4
ENST00000620576.4
ENST00000620055.4
ENST00000610565.4
ENST00000620250.1
C-C motif chemokine ligand 4 like 2
chr16_+_33009175 3.73 ENST00000565407.2
immunoglobulin heavy variable 3/OR16-8 (non-functional)
chr22_+_22322452 3.73 ENST00000390290.3
immunoglobulin lambda variable 1-51
chr1_-_113871665 3.70 ENST00000528414.5
ENST00000460620.5
ENST00000359785.10
ENST00000420377.6
ENST00000525799.1
ENST00000538253.5
protein tyrosine phosphatase non-receptor type 22
chrX_+_10158448 3.69 ENST00000380829.5
ENST00000421085.7
ENST00000674669.1
ENST00000454850.1
chloride voltage-gated channel 4
chr4_-_46909235 3.67 ENST00000505102.1
ENST00000355591.8
cytochrome c oxidase subunit 7B2
chr2_+_89936859 3.65 ENST00000474213.1
immunoglobulin kappa variable 2D-30
chr11_+_49028823 3.63 ENST00000332682.9
tripartite motif containing 49B
chr12_-_11269805 3.63 ENST00000538488.2
proline rich protein BstNI subfamily 3
chr16_-_33845229 3.63 ENST00000569103.2
immunoglobulin heavy variable 3/OR16-17 (non-functional)
chr3_+_149474688 3.63 ENST00000305354.5
ENST00000465758.1
transmembrane 4 L six family member 4
chr12_-_14961559 3.50 ENST00000228945.9
ENST00000541546.5
Rho GDP dissociation inhibitor beta
chr15_-_19988117 3.48 ENST00000558565.2
immunoglobulin heavy variable 3/OR15-7 (pseudogene)
chr11_-_102705737 3.46 ENST00000260229.5
matrix metallopeptidase 27
chr2_-_159798234 3.43 ENST00000429078.6
ENST00000553424.5
CD302 molecule
chr20_-_1657714 3.39 ENST00000216927.4
ENST00000344103.8
signal regulatory protein gamma
chr3_-_39281663 3.36 ENST00000358309.3
C-X3-C motif chemokine receptor 1
chr1_-_150765785 3.32 ENST00000680311.1
ENST00000681728.1
ENST00000680288.1
cathepsin S
chr6_-_132763424 3.32 ENST00000532012.1
ENST00000525270.5
ENST00000530536.5
ENST00000524919.5
vanin 2
chr13_-_46182136 3.30 ENST00000323076.7
lymphocyte cytosolic protein 1
chr14_-_22957100 3.30 ENST00000555367.5
HAUS augmin like complex subunit 4
chr4_-_39032343 3.29 ENST00000381938.4
transmembrane protein 156
chr16_+_32066065 3.27 ENST00000354689.6
immunoglobulin heavy variable 3/OR16-9 (non-functional)
chr21_-_14658812 3.26 ENST00000647101.1
SAM domain, SH3 domain and nuclear localization signals 1
chr14_-_24576240 3.24 ENST00000216336.3
cathepsin G
chr4_+_101813810 3.23 ENST00000444316.2
B cell scaffold protein with ankyrin repeats 1
chr4_-_69214743 3.21 ENST00000446444.2
UDP glucuronosyltransferase family 2 member B11
chr3_+_35680994 3.19 ENST00000441454.5
cAMP regulated phosphoprotein 21
chr5_+_55102635 3.18 ENST00000274306.7
granzyme A
chr12_-_122500520 3.17 ENST00000540586.1
ENST00000543897.5
zinc finger CCHC-type containing 8
chr11_-_129024157 3.16 ENST00000392657.7
Rho GTPase activating protein 32
chr16_+_33802683 3.15 ENST00000570121.2
immunoglobulin heavy variable 3/OR16-12 (non-functional)
chr17_-_37643422 3.10 ENST00000617633.5
DExD-box helicase 52
chr8_+_28891304 3.09 ENST00000355231.9
homeobox containing 1
chr22_-_18936142 3.08 ENST00000438924.5
ENST00000457083.1
ENST00000357068.11
ENST00000420436.5
ENST00000334029.6
ENST00000610940.4
proline dehydrogenase 1
chr5_-_20575850 3.07 ENST00000507958.5
cadherin 18
chr5_+_140848360 3.05 ENST00000532602.2
protocadherin alpha 9
chr7_+_74209386 3.04 ENST00000344995.9
linker for activation of T cells family member 2
chr6_-_52763473 3.03 ENST00000493422.3
glutathione S-transferase alpha 2
chr17_-_64390852 3.03 ENST00000563924.6
platelet and endothelial cell adhesion molecule 1
chr7_-_150323489 3.02 ENST00000683684.1
ENST00000478393.5
actin related protein 3C
chr12_-_9607903 3.01 ENST00000229402.4
killer cell lectin like receptor B1
chr11_+_121576760 3.01 ENST00000532694.5
ENST00000534286.5
sortilin related receptor 1
chr6_-_49744434 2.98 ENST00000433368.6
ENST00000354620.4
cysteine rich secretory protein 3
chr4_+_68815991 2.98 ENST00000265403.12
ENST00000458688.2
UDP glucuronosyltransferase family 2 member B10
chr14_-_106005574 2.95 ENST00000390595.3
immunoglobulin heavy variable 1-3
chr14_-_22957061 2.92 ENST00000557591.5
ENST00000541587.6
ENST00000490506.5
ENST00000554406.1
HAUS augmin like complex subunit 4
chr1_+_174875505 2.91 ENST00000486220.5
RAB GTPase activating protein 1 like
chr2_+_165239432 2.90 ENST00000636071.2
ENST00000636985.2
sodium voltage-gated channel alpha subunit 2
chr1_-_207052980 2.89 ENST00000367084.1
YOD1 deubiquitinase
chr12_+_25052512 2.88 ENST00000557489.5
ENST00000354454.7
ENST00000536173.5
inositol 1,4,5-triphosphate receptor associated 2
chr2_+_68734861 2.87 ENST00000467265.5
Rho GTPase activating protein 25
chr20_-_36951837 2.87 ENST00000262878.5
SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1
chr6_+_139135063 2.87 ENST00000367658.3
hdc homolog, cell cycle regulator
chr4_-_152382522 2.86 ENST00000296555.11
F-box and WD repeat domain containing 7
chrY_-_6872608 2.84 ENST00000383036.1
amelogenin Y-linked
chrX_+_109536641 2.84 ENST00000372107.5
nuclear transport factor 2 like export factor 2
chr5_-_132556809 2.84 ENST00000450655.1
interleukin 5
chr6_-_132734692 2.82 ENST00000509351.5
ENST00000417437.6
ENST00000423615.6
ENST00000427187.6
ENST00000414302.7
ENST00000367927.9
ENST00000450865.2
vanin 3
chr4_+_69280472 2.79 ENST00000335568.10
ENST00000511240.1
UDP glucuronosyltransferase family 2 member B28
chr2_+_165239388 2.78 ENST00000424833.5
ENST00000375437.7
ENST00000631182.3
sodium voltage-gated channel alpha subunit 2
chr16_+_10386049 2.78 ENST00000562527.5
ENST00000396559.5
ENST00000396560.6
ENST00000562102.5
ENST00000543967.5
ENST00000569939.5
ENST00000569900.5
activating transcription factor 7 interacting protein 2
chr1_+_27872536 2.76 ENST00000328928.11
ENST00000373921.8
ENST00000373925.5
ENST00000373927.7
ENST00000427466.1
ENST00000442118.5
thymocyte selection associated family member 2
chr12_+_9827517 2.73 ENST00000537723.5
killer cell lectin like receptor F1
chr2_-_89297785 2.72 ENST00000465170.1
immunoglobulin kappa variable 1-37 (non-functional)
chr8_-_133102477 2.72 ENST00000522119.5
ENST00000523610.5
ENST00000338087.10
ENST00000521302.5
ENST00000519558.5
ENST00000519747.5
ENST00000517648.5
Src like adaptor
chr12_+_8843236 2.70 ENST00000541459.5
alpha-2-macroglobulin like 1
chr20_+_24949256 2.69 ENST00000480798.2
cystatin F
chr12_-_7503841 2.68 ENST00000359156.8
CD163 molecule
chr4_-_99435396 2.66 ENST00000209665.8
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_+_207053229 2.65 ENST00000367080.8
ENST00000367079.3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr2_+_68734773 2.64 ENST00000409202.8
Rho GTPase activating protein 25
chr4_+_40191037 2.63 ENST00000505618.5
ras homolog family member H
chr15_-_19965101 2.63 ENST00000338912.5
immunoglobulin heavy variable 1/OR15-9 (non-functional)
chr14_-_22957128 2.60 ENST00000342454.12
ENST00000555986.5
ENST00000554516.5
ENST00000347758.6
ENST00000206474.11
ENST00000555040.5
HAUS augmin like complex subunit 4
chr19_-_40413364 2.60 ENST00000291825.11
ENST00000324001.8
periaxin
chr12_+_11649666 2.58 ENST00000396373.9
ETS variant transcription factor 6
chr14_+_92121953 2.56 ENST00000298875.9
ENST00000553427.5
cleavage and polyadenylation specific factor 2
chr3_+_4680617 2.56 ENST00000648212.1
inositol 1,4,5-trisphosphate receptor type 1
chr1_+_117420597 2.53 ENST00000449370.6
mannosidase alpha class 1A member 2
chr12_-_53207271 2.53 ENST00000552972.5
ENST00000422257.7
integrin subunit beta 7
chr12_+_56468561 2.52 ENST00000338146.7
SPRY domain containing 4
chr4_-_67545464 2.51 ENST00000273853.11
centromere protein C
chr16_-_21652598 2.51 ENST00000569602.1
ENST00000268389.6
immunoglobulin superfamily member 6
chr2_+_143129379 2.50 ENST00000295095.11
Rho GTPase activating protein 15
chr15_+_90352239 2.50 ENST00000354377.8
ENST00000379090.9
zinc finger protein 774
chr4_+_69096467 2.49 ENST00000305231.12
UDP glucuronosyltransferase family 2 member B7
chr12_+_133181409 2.49 ENST00000416488.5
ENST00000228289.9
ENST00000541211.6
ENST00000536435.7
ENST00000500625.7
ENST00000539248.6
ENST00000542711.6
ENST00000536899.6
ENST00000542986.6
ENST00000611984.4
ENST00000541975.2
zinc finger protein 268
chr9_-_86354386 2.47 ENST00000277141.10
ENST00000375963.8
terminal uridylyl transferase 7
chr2_-_89222461 2.45 ENST00000482769.1
immunoglobulin kappa variable 2-28
chr15_+_99251362 2.45 ENST00000558879.5
ENST00000301981.8
ENST00000447360.6
ENST00000558172.5
ENST00000561276.5
ENST00000331450.9
leucine rich repeat containing 28

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.0 15.0 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
3.7 11.0 GO:0071461 cellular response to redox state(GO:0071461)
3.1 12.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
2.7 8.2 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
2.3 6.9 GO:0072709 cellular response to sorbitol(GO:0072709)
2.3 9.0 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
1.8 272.4 GO:0006958 complement activation, classical pathway(GO:0006958)
1.8 5.5 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
1.8 5.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
1.7 5.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
1.7 5.0 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
1.6 9.4 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
1.6 4.7 GO:0016256 N-glycan processing to lysosome(GO:0016256)
1.5 4.4 GO:1904845 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
1.2 4.7 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
1.2 7.0 GO:0097338 response to clozapine(GO:0097338)
1.1 3.4 GO:0043012 regulation of fusion of sperm to egg plasma membrane(GO:0043012)
1.1 3.3 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
1.1 3.3 GO:0034769 basement membrane disassembly(GO:0034769)
1.1 3.3 GO:0070340 detection of bacterial lipoprotein(GO:0042494) detection of triacyl bacterial lipopeptide(GO:0042495) detection of bacterial lipopeptide(GO:0070340)
1.1 4.3 GO:0045401 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401)
1.1 4.2 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
1.0 10.5 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
1.0 3.0 GO:1902948 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) regulation of neurofibrillary tangle assembly(GO:1902996) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
1.0 3.0 GO:0050904 diapedesis(GO:0050904)
1.0 3.9 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.9 3.8 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.9 9.3 GO:1900165 negative regulation of interleukin-6 secretion(GO:1900165)
0.9 3.6 GO:0005986 sucrose biosynthetic process(GO:0005986)
0.9 1.8 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.9 2.7 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.9 3.5 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.9 6.1 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.9 3.4 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.8 10.1 GO:0015939 pantothenate metabolic process(GO:0015939)
0.8 2.5 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
0.8 3.3 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.8 8.8 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.8 2.4 GO:0035915 pore formation in membrane of other organism(GO:0035915)
0.8 3.2 GO:0071918 urea transmembrane transport(GO:0071918)
0.8 2.3 GO:1903004 regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006)
0.8 7.6 GO:0038124 toll-like receptor TLR6:TLR2 signaling pathway(GO:0038124) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.7 12.0 GO:0006910 phagocytosis, recognition(GO:0006910)
0.7 3.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.7 2.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.7 7.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.7 1.3 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.6 107.0 GO:0002377 immunoglobulin production(GO:0002377)
0.6 4.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.6 2.6 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.6 2.5 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.6 2.5 GO:0036369 transcription factor catabolic process(GO:0036369)
0.6 1.2 GO:0030573 bile acid catabolic process(GO:0030573)
0.6 1.8 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.6 4.7 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.6 2.3 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.6 1.7 GO:0031393 negative regulation of prostaglandin biosynthetic process(GO:0031393)
0.6 1.7 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.5 1.1 GO:0052331 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.5 31.0 GO:0006730 one-carbon metabolic process(GO:0006730)
0.5 3.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.5 3.2 GO:0070943 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.5 0.5 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.5 2.1 GO:1902857 nonmotile primary cilium assembly(GO:0035058) regulation of nonmotile primary cilium assembly(GO:1902855) positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.5 0.5 GO:1903487 regulation of lactation(GO:1903487)
0.5 2.6 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.5 2.1 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
0.5 10.4 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.5 5.0 GO:0007028 cytoplasm organization(GO:0007028)
0.5 1.5 GO:0006711 estrogen catabolic process(GO:0006711)
0.5 4.0 GO:0014056 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056)
0.5 6.5 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.5 14.9 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.5 2.0 GO:0051697 protein delipidation(GO:0051697)
0.5 9.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.5 1.5 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.5 0.5 GO:0015942 formate metabolic process(GO:0015942) histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.5 1.4 GO:0036245 cellular response to menadione(GO:0036245)
0.5 1.4 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.4 1.3 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
0.4 2.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.4 2.5 GO:0046092 deoxycytidine metabolic process(GO:0046092)
0.4 1.2 GO:0060003 copper ion export(GO:0060003)
0.4 2.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.4 1.2 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.4 2.9 GO:0046061 dATP catabolic process(GO:0046061)
0.4 2.0 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.4 1.6 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.4 1.2 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.4 3.1 GO:0070995 NADPH oxidation(GO:0070995)
0.4 4.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.4 1.1 GO:1901876 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
0.4 6.0 GO:0098712 amino acid import across plasma membrane(GO:0089718) L-glutamate import across plasma membrane(GO:0098712)
0.4 1.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.4 0.7 GO:0001781 neutrophil apoptotic process(GO:0001781) regulation of neutrophil apoptotic process(GO:0033029)
0.4 2.5 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.4 1.4 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.3 2.0 GO:0051945 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.3 1.7 GO:0034721 histone H3-K4 demethylation, trimethyl-H3-K4-specific(GO:0034721)
0.3 1.0 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.3 0.7 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.3 1.0 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.3 1.3 GO:2001193 gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) negative regulation of interferon-gamma biosynthetic process(GO:0045077) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
0.3 2.6 GO:0003138 regulation of germinal center formation(GO:0002634) primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.3 2.3 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.3 2.6 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.3 2.5 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.3 2.2 GO:0002933 lipid hydroxylation(GO:0002933)
0.3 0.6 GO:0002331 pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
0.3 0.6 GO:1905237 response to cyclosporin A(GO:1905237)
0.3 0.9 GO:0010046 response to mycotoxin(GO:0010046)
0.3 0.3 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.3 1.5 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.3 0.9 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.3 0.9 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.3 2.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.3 0.9 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.3 1.5 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.3 0.9 GO:2000296 negative regulation of hydrogen peroxide catabolic process(GO:2000296)
0.3 2.0 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.3 0.8 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.3 1.4 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.3 0.3 GO:0090212 negative regulation of establishment of blood-brain barrier(GO:0090212)
0.3 1.3 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.3 0.8 GO:1903718 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) cellular response to oleic acid(GO:0071400) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
0.3 1.5 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.3 0.8 GO:0015722 canalicular bile acid transport(GO:0015722)
0.2 0.7 GO:0009720 detection of hormone stimulus(GO:0009720)
0.2 16.1 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.2 1.0 GO:0060023 soft palate development(GO:0060023)
0.2 2.4 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.2 1.0 GO:0090301 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.2 1.2 GO:0010840 regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.2 1.6 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.2 1.4 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 0.5 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.2 1.6 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 0.9 GO:0030035 microspike assembly(GO:0030035)
0.2 0.7 GO:0061150 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) deltoid tuberosity development(GO:0035993) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.2 1.4 GO:1900004 negative regulation of serine-type endopeptidase activity(GO:1900004) negative regulation of serine-type peptidase activity(GO:1902572)
0.2 0.7 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.2 2.4 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.2 0.2 GO:1903781 positive regulation of cardiac conduction(GO:1903781)
0.2 0.7 GO:0098759 response to interleukin-8(GO:0098758) cellular response to interleukin-8(GO:0098759)
0.2 0.9 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.2 4.8 GO:0034505 tooth mineralization(GO:0034505)
0.2 0.4 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
0.2 0.6 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.2 5.1 GO:0045730 respiratory burst(GO:0045730)
0.2 3.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.2 2.2 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.2 2.0 GO:0006265 DNA topological change(GO:0006265)
0.2 3.8 GO:0015671 oxygen transport(GO:0015671)
0.2 1.0 GO:1901963 glial cell fate determination(GO:0007403) oviduct development(GO:0060066) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.2 1.4 GO:0042989 sequestering of actin monomers(GO:0042989)
0.2 1.4 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.2 0.6 GO:0007343 egg activation(GO:0007343)
0.2 10.7 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.2 3.7 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.2 0.6 GO:1990637 response to prolactin(GO:1990637)
0.2 1.2 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.2 8.4 GO:0070206 protein trimerization(GO:0070206)
0.2 1.9 GO:0043249 erythrocyte maturation(GO:0043249)
0.2 0.6 GO:0044565 dendritic cell proliferation(GO:0044565)
0.2 1.9 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 0.8 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.2 3.6 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.2 1.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 4.3 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.2 4.3 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.2 1.1 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.2 1.3 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.2 0.7 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.2 0.6 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.2 2.8 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.2 0.7 GO:0010966 regulation of phosphate transport(GO:0010966)
0.2 0.7 GO:0045414 regulation of interleukin-8 biosynthetic process(GO:0045414) positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.2 0.9 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.2 1.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 2.9 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.2 1.4 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.2 0.3 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.2 3.0 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.2 1.7 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.2 7.1 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.2 0.7 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2 0.9 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.2 0.9 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2 2.7 GO:0060046 regulation of acrosome reaction(GO:0060046)
0.2 2.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 1.6 GO:0032264 IMP salvage(GO:0032264)
0.2 0.5 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.2 2.8 GO:0051382 kinetochore assembly(GO:0051382)
0.2 1.0 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.2 0.6 GO:1904640 response to methionine(GO:1904640)
0.2 0.6 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.2 2.2 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.2 1.7 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.2 2.8 GO:0072643 interferon-gamma secretion(GO:0072643)
0.2 0.5 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.2 1.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.2 1.1 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.2 0.3 GO:1903413 cellular response to bile acid(GO:1903413)
0.2 1.4 GO:0009249 protein lipoylation(GO:0009249)
0.1 1.0 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.1 1.0 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.1 14.7 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.1 1.0 GO:0044351 macropinocytosis(GO:0044351)
0.1 0.6 GO:1900827 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 1.3 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.7 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 1.0 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 1.1 GO:0016139 glycoside catabolic process(GO:0016139)
0.1 1.2 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.1 2.3 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 2.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 0.4 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1 0.5 GO:0043201 response to leucine(GO:0043201)
0.1 0.5 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 0.8 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.1 1.9 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 2.2 GO:0044065 regulation of respiratory system process(GO:0044065)
0.1 1.5 GO:1904903 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.1 0.8 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.5 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 1.2 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.1 1.2 GO:0034465 response to carbon monoxide(GO:0034465)
0.1 0.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 2.1 GO:0008210 estrogen metabolic process(GO:0008210)
0.1 0.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 1.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 1.9 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.1 0.8 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.8 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 1.0 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 5.8 GO:0002279 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.1 0.7 GO:0000012 single strand break repair(GO:0000012)
0.1 5.8 GO:0019228 neuronal action potential(GO:0019228)
0.1 0.3 GO:0036233 glycine import(GO:0036233)
0.1 0.5 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.8 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.8 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.3 GO:0046603 negative regulation of mitotic centrosome separation(GO:0046603)
0.1 0.3 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.1 1.6 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.6 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.1 0.3 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.3 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.1 0.4 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 0.5 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.1 1.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 2.2 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 0.8 GO:0002775 antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
0.1 1.6 GO:0050832 defense response to fungus(GO:0050832)
0.1 1.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.1 4.3 GO:0006953 acute-phase response(GO:0006953)
0.1 1.1 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 2.7 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 2.9 GO:0033198 response to ATP(GO:0033198)
0.1 1.0 GO:0048263 determination of dorsal identity(GO:0048263)
0.1 1.0 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 0.6 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.1 0.6 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 2.9 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 1.0 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.1 0.3 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 0.6 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 2.3 GO:0044458 motile cilium assembly(GO:0044458)
0.1 0.7 GO:0003344 pericardium morphogenesis(GO:0003344)
0.1 2.5 GO:0019835 cytolysis(GO:0019835)
0.1 0.9 GO:0033227 dsRNA transport(GO:0033227)
0.1 2.6 GO:0006298 mismatch repair(GO:0006298)
0.1 4.7 GO:0006968 cellular defense response(GO:0006968)
0.1 4.7 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.1 1.7 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 0.8 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.1 0.2 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.2 GO:0009595 detection of biotic stimulus(GO:0009595)
0.1 0.8 GO:0044364 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.1 2.1 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 1.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.6 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.6 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.1 2.1 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 0.4 GO:0035617 stress granule disassembly(GO:0035617)
0.1 0.4 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.1 1.5 GO:0018345 protein palmitoylation(GO:0018345)
0.1 1.0 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.1 0.6 GO:0009642 response to light intensity(GO:0009642)
0.1 0.9 GO:0015074 DNA integration(GO:0015074)
0.1 0.5 GO:0061709 reticulophagy(GO:0061709)
0.1 1.4 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.1 0.5 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 1.3 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.1 6.3 GO:0031295 T cell costimulation(GO:0031295)
0.1 0.1 GO:0035502 metanephric part of ureteric bud development(GO:0035502)
0.1 0.4 GO:0015886 heme transport(GO:0015886)
0.1 1.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 5.5 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.1 0.4 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 2.1 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.1 0.5 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.1 0.5 GO:0046415 urate metabolic process(GO:0046415)
0.1 0.2 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
0.1 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.1 0.7 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 1.0 GO:0046599 regulation of centriole replication(GO:0046599)
0.1 0.4 GO:0015705 iodide transport(GO:0015705)
0.1 0.9 GO:0042572 retinol metabolic process(GO:0042572)
0.1 1.8 GO:0032731 positive regulation of interleukin-1 beta production(GO:0032731)
0.1 0.9 GO:0010447 response to acidic pH(GO:0010447)
0.1 1.8 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 2.6 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.8 GO:0042346 positive regulation of NF-kappaB import into nucleus(GO:0042346)
0.1 1.2 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1 1.6 GO:0040019 positive regulation of embryonic development(GO:0040019)
0.1 3.1 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.1 0.2 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.1 0.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 1.3 GO:0016578 histone deubiquitination(GO:0016578)
0.1 0.9 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.1 1.6 GO:0007608 sensory perception of smell(GO:0007608)
0.1 0.3 GO:0090344 negative regulation of cell aging(GO:0090344)
0.1 1.7 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1 1.4 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 0.1 GO:0006447 regulation of translational initiation by iron(GO:0006447)
0.1 0.5 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.7 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.1 GO:0043691 reverse cholesterol transport(GO:0043691)
0.0 0.7 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.0 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.5 GO:0006552 leucine catabolic process(GO:0006552)
0.0 1.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.3 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 1.0 GO:0016180 snRNA processing(GO:0016180)
0.0 1.3 GO:0008209 androgen metabolic process(GO:0008209)
0.0 1.2 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.0 1.4 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.5 GO:0050942 positive regulation of pigment cell differentiation(GO:0050942)
0.0 0.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.2 GO:1901907 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 1.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 1.3 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.9 GO:0010165 response to X-ray(GO:0010165)
0.0 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.2 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.2 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 2.4 GO:0042742 defense response to bacterium(GO:0042742)
0.0 0.7 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 3.3 GO:0001892 embryonic placenta development(GO:0001892)
0.0 0.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.0 0.5 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.5 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.7 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.0 0.2 GO:0039526 suppression by virus of host apoptotic process(GO:0019050) modulation by virus of host apoptotic process(GO:0039526) cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.0 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.0 0.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 1.0 GO:0001881 receptor recycling(GO:0001881)
0.0 0.5 GO:0015884 folic acid transport(GO:0015884)
0.0 0.4 GO:0031297 replication fork processing(GO:0031297)
0.0 0.5 GO:0030220 platelet formation(GO:0030220)
0.0 0.4 GO:0042554 superoxide anion generation(GO:0042554)
0.0 0.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.2 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.8 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 1.8 GO:0070671 interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.0 0.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.0 0.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.8 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 1.8 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 0.6 GO:0032760 positive regulation of tumor necrosis factor production(GO:0032760) positive regulation of tumor necrosis factor superfamily cytokine production(GO:1903557)
0.0 0.3 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 1.9 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.3 GO:0060039 pericardium development(GO:0060039)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.4 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 1.6 GO:0031214 biomineral tissue development(GO:0031214)
0.0 0.1 GO:0046116 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.4 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.0 1.1 GO:0032922 circadian regulation of gene expression(GO:0032922)
0.0 1.0 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 1.8 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 3.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.4 GO:0007398 ectoderm development(GO:0007398)
0.0 0.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 1.0 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.5 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.6 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.2 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.5 GO:1903959 regulation of anion transmembrane transport(GO:1903959)
0.0 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.4 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 0.4 GO:0006688 glycosphingolipid biosynthetic process(GO:0006688)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.4 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.0 0.3 GO:0015695 organic cation transport(GO:0015695)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.0 12.0 GO:0071756 IgM immunoglobulin complex(GO:0071753) IgM immunoglobulin complex, circulating(GO:0071754) pentameric IgM immunoglobulin complex(GO:0071756)
1.7 86.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
1.4 8.2 GO:0032437 cuticular plate(GO:0032437)
1.2 23.7 GO:0042613 MHC class II protein complex(GO:0042613)
1.2 4.7 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
1.1 5.7 GO:0032299 ribonuclease H2 complex(GO:0032299)
1.1 3.3 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
1.0 8.8 GO:0070652 HAUS complex(GO:0070652)
1.0 2.9 GO:0033011 perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.9 6.3 GO:0097165 nuclear stress granule(GO:0097165)
0.9 10.6 GO:0005577 fibrinogen complex(GO:0005577)
0.7 9.9 GO:0043020 NADPH oxidase complex(GO:0043020)
0.6 4.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.6 101.9 GO:0072562 blood microparticle(GO:0072562)
0.5 2.1 GO:0044307 dendritic branch(GO:0044307)
0.5 3.5 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.5 2.4 GO:0019815 B cell receptor complex(GO:0019815)
0.5 3.3 GO:0036021 endolysosome lumen(GO:0036021)
0.5 1.4 GO:0005927 muscle tendon junction(GO:0005927)
0.4 2.5 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.4 2.3 GO:0033553 rDNA heterochromatin(GO:0033553)
0.3 1.7 GO:1990031 pinceau fiber(GO:1990031)
0.3 11.3 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.3 1.0 GO:0097224 sperm connecting piece(GO:0097224)
0.3 1.0 GO:0005592 collagen type XI trimer(GO:0005592)
0.3 10.8 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.3 1.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.3 0.9 GO:0000805 X chromosome(GO:0000805)
0.3 7.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.3 0.9 GO:0097679 other organism cytoplasm(GO:0097679)
0.3 0.9 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.3 4.0 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.3 2.6 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.3 1.9 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.3 1.9 GO:0031415 NatA complex(GO:0031415)
0.3 5.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 2.6 GO:0005955 calcineurin complex(GO:0005955)
0.2 1.6 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 1.5 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 0.8 GO:0097179 protease inhibitor complex(GO:0097179)
0.2 2.3 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.2 0.6 GO:0043293 apoptosome(GO:0043293)
0.2 11.7 GO:0001772 immunological synapse(GO:0001772)
0.2 4.9 GO:0032982 myosin filament(GO:0032982)
0.2 1.8 GO:0044194 cytolytic granule(GO:0044194)
0.2 0.9 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 1.8 GO:0032389 MutLalpha complex(GO:0032389)
0.2 4.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.2 2.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 2.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.2 1.0 GO:0070554 synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.2 1.0 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.2 2.9 GO:0042101 T cell receptor complex(GO:0042101)
0.2 1.8 GO:0032300 mismatch repair complex(GO:0032300)
0.2 4.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 0.5 GO:0070876 SOSS complex(GO:0070876)
0.2 6.2 GO:0034451 centriolar satellite(GO:0034451)
0.2 1.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.5 GO:0043596 nuclear replication fork(GO:0043596)
0.1 29.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 3.3 GO:0001891 phagocytic cup(GO:0001891)
0.1 1.1 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 1.9 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 1.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 2.4 GO:0000786 nucleosome(GO:0000786)
0.1 2.0 GO:0045277 respiratory chain complex IV(GO:0045277)
0.1 3.3 GO:0042629 mast cell granule(GO:0042629)
0.1 0.2 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.1 1.2 GO:0032039 integrator complex(GO:0032039)
0.1 1.5 GO:0000815 ESCRT III complex(GO:0000815)
0.1 3.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 1.1 GO:0070938 contractile ring(GO:0070938)
0.1 0.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 1.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 3.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 6.5 GO:0015030 Cajal body(GO:0015030)
0.1 8.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.1 0.6 GO:0036157 outer dynein arm(GO:0036157)
0.1 1.0 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.1 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.5 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.2 GO:0035102 PRC1 complex(GO:0035102)
0.1 8.8 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.0 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 2.9 GO:0000791 euchromatin(GO:0000791)
0.1 0.9 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 1.5 GO:0097225 sperm midpiece(GO:0097225)
0.1 2.1 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 6.1 GO:0005902 microvillus(GO:0005902)
0.1 5.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.0 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 0.6 GO:0042788 polysomal ribosome(GO:0042788)
0.1 1.8 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.5 GO:0060091 kinocilium(GO:0060091)
0.1 2.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 2.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.1 1.0 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 0.9 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 2.4 GO:0031430 M band(GO:0031430)
0.1 0.7 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.1 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
0.1 94.8 GO:0005615 extracellular space(GO:0005615)
0.1 3.6 GO:0048786 presynaptic active zone(GO:0048786)
0.1 1.3 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 2.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.4 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 0.5 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.6 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.5 GO:0031089 platelet dense granule lumen(GO:0031089)
0.1 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.4 GO:0016011 dystroglycan complex(GO:0016011) sarcoglycan complex(GO:0016012)
0.1 3.5 GO:0036064 ciliary basal body(GO:0036064)
0.0 0.6 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.3 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 1.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.4 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.6 GO:0033268 node of Ranvier(GO:0033268)
0.0 0.5 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 1.3 GO:0030057 desmosome(GO:0030057)
0.0 0.9 GO:0030673 axolemma(GO:0030673)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.7 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.9 GO:0008328 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 3.0 GO:0043204 perikaryon(GO:0043204)
0.0 2.9 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.0 0.2 GO:0044754 autolysosome(GO:0044754)
0.0 0.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0036038 MKS complex(GO:0036038)
0.0 0.9 GO:0005581 collagen trimer(GO:0005581)
0.0 0.8 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0097546 ciliary base(GO:0097546)
0.0 0.3 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.4 GO:0098576 lumenal side of membrane(GO:0098576)
0.0 2.6 GO:0032993 protein-DNA complex(GO:0032993)
0.0 0.4 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.4 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.3 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0001533 cornified envelope(GO:0001533)
0.0 1.0 GO:0035579 specific granule membrane(GO:0035579)
0.0 0.4 GO:0090544 BAF-type complex(GO:0090544)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 12.3 GO:0035276 ethanol binding(GO:0035276)
3.0 30.0 GO:0004064 arylesterase activity(GO:0004064)
2.7 8.2 GO:0008859 exoribonuclease II activity(GO:0008859)
2.5 10.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
2.3 9.0 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
1.9 5.6 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
1.8 9.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
1.6 378.1 GO:0003823 antigen binding(GO:0003823)
1.6 9.3 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
1.4 11.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.3 13.0 GO:0005549 odorant binding(GO:0005549)
1.2 6.0 GO:0032395 MHC class II receptor activity(GO:0032395)
1.2 4.7 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
1.1 3.3 GO:0005137 interleukin-5 receptor binding(GO:0005137)
1.1 3.3 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
1.0 3.0 GO:0004556 alpha-amylase activity(GO:0004556)
1.0 2.9 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.9 2.8 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.9 3.6 GO:0042132 fructose 1,6-bisphosphate 1-phosphatase activity(GO:0042132)
0.9 12.8 GO:0019957 C-C chemokine binding(GO:0019957)
0.8 3.2 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.8 2.3 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.8 6.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.8 3.8 GO:0004522 ribonuclease A activity(GO:0004522)
0.8 11.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.7 11.0 GO:0032393 MHC class I receptor activity(GO:0032393)
0.7 2.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.7 2.9 GO:0032567 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793) guanyl deoxyribonucleotide binding(GO:0032560) dGTP binding(GO:0032567)
0.7 2.1 GO:0035375 zymogen binding(GO:0035375)
0.7 12.2 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.7 2.0 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.7 13.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.7 5.3 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.6 3.9 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.6 1.9 GO:0016497 substance K receptor activity(GO:0016497)
0.6 3.5 GO:0009378 four-way junction helicase activity(GO:0009378)
0.6 2.3 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.6 14.3 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.6 1.7 GO:0045322 unmethylated CpG binding(GO:0045322)
0.6 1.7 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.5 4.9 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.5 8.1 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.5 2.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.5 4.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.5 1.5 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.5 1.4 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.4 2.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.4 7.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.4 1.3 GO:0032093 SAM domain binding(GO:0032093)
0.4 1.7 GO:0004982 N-formyl peptide receptor activity(GO:0004982) scavenger receptor binding(GO:0005124)
0.4 1.2 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.4 1.6 GO:1904492 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
0.4 1.6 GO:0030492 hemoglobin binding(GO:0030492)
0.4 1.2 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.4 1.9 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.4 1.5 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.4 5.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.4 1.1 GO:0017129 triglyceride binding(GO:0017129)
0.4 4.0 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.4 2.5 GO:0004137 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
0.4 1.8 GO:0051400 BH domain binding(GO:0051400)
0.4 1.4 GO:0035473 lipase binding(GO:0035473)
0.3 0.3 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.3 2.0 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.3 2.4 GO:0035325 Toll-like receptor binding(GO:0035325)
0.3 1.4 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.3 1.7 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.3 1.0 GO:0004877 complement component C4b receptor activity(GO:0001861) complement component C3b receptor activity(GO:0004877)
0.3 1.3 GO:0004348 glucosylceramidase activity(GO:0004348)
0.3 2.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3 2.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.3 6.5 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 1.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.3 1.2 GO:0070051 fibrinogen binding(GO:0070051)
0.3 1.5 GO:0004370 glycerol kinase activity(GO:0004370)
0.3 4.4 GO:0005344 oxygen transporter activity(GO:0005344)
0.3 2.8 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.3 3.1 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.3 0.8 GO:0052816 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.3 4.8 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.3 5.0 GO:0016805 dipeptidase activity(GO:0016805)
0.3 1.1 GO:0019862 IgA binding(GO:0019862)
0.3 4.4 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.3 2.5 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.2 0.7 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.2 2.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.2 1.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.2 1.4 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.2 2.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 1.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.2 7.7 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 7.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 4.9 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.2 0.7 GO:0030343 vitamin D3 25-hydroxylase activity(GO:0030343) vitamin D 25-hydroxylase activity(GO:0070643)
0.2 0.4 GO:0070568 guanylyltransferase activity(GO:0070568)
0.2 0.7 GO:0019959 interleukin-8 binding(GO:0019959)
0.2 1.9 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.2 8.9 GO:0001784 phosphotyrosine binding(GO:0001784)
0.2 2.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 5.8 GO:0003951 NAD+ kinase activity(GO:0003951)
0.2 1.2 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 1.6 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.2 2.6 GO:0003680 AT DNA binding(GO:0003680)
0.2 1.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 3.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.2 0.8 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.2 7.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 0.6 GO:0004939 beta-adrenergic receptor activity(GO:0004939)
0.2 0.6 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.2 0.6 GO:0005502 11-cis retinal binding(GO:0005502)
0.2 0.8 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.2 0.6 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.2 0.9 GO:0042296 ISG15 transferase activity(GO:0042296)
0.2 2.6 GO:0008097 5S rRNA binding(GO:0008097)
0.2 0.7 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.2 0.7 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.2 0.6 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.2 1.6 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.2 1.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 0.5 GO:0005042 netrin receptor activity(GO:0005042)
0.2 2.7 GO:0001054 RNA polymerase I activity(GO:0001054)
0.2 2.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 3.6 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 0.9 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.2 0.9 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 1.9 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.2 6.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.2 1.6 GO:0005221 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.2 1.0 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 0.5 GO:0004967 glucagon receptor activity(GO:0004967)
0.2 0.9 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.2 0.8 GO:0004690 cyclic nucleotide-dependent protein kinase activity(GO:0004690) cGMP-dependent protein kinase activity(GO:0004692)
0.2 1.4 GO:0034056 estrogen response element binding(GO:0034056)
0.2 0.6 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.2 2.3 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 1.8 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 6.0 GO:0017091 AU-rich element binding(GO:0017091)
0.1 4.2 GO:0071949 FAD binding(GO:0071949)
0.1 1.6 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.1 0.4 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.4 GO:0003973 (S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.1 1.0 GO:0032027 myosin light chain binding(GO:0032027)
0.1 1.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.6 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.1 3.7 GO:0001968 fibronectin binding(GO:0001968)
0.1 0.4 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.1 0.4 GO:0043035 chromatin insulator sequence binding(GO:0043035)
0.1 1.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 3.5 GO:0030983 mismatched DNA binding(GO:0030983)
0.1 0.8 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.1 0.7 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.4 GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577)
0.1 0.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.8 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 4.8 GO:0001972 retinoic acid binding(GO:0001972)
0.1 1.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.5 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) polynucleotide phosphatase activity(GO:0098518)
0.1 1.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 4.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.4 GO:0032090 Pyrin domain binding(GO:0032090)
0.1 1.6 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.7 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.1 1.4 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen(GO:0016713)
0.1 1.1 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.7 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.6 GO:0004875 complement receptor activity(GO:0004875)
0.1 0.5 GO:0050262 ribosylnicotinamide kinase activity(GO:0050262) ribosylnicotinate kinase activity(GO:0061769)
0.1 2.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.3 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 1.4 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 0.8 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.1 0.4 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 1.0 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 1.1 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.7 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 1.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.7 GO:0005499 vitamin D binding(GO:0005499)
0.1 1.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.4 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 1.3 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 0.5 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.1 1.1 GO:0015643 toxic substance binding(GO:0015643)
0.1 1.9 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.1 0.9 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 2.7 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.9 GO:0031013 troponin I binding(GO:0031013)
0.1 2.5 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.0 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.1 0.5 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 1.0 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.1 0.3 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.3 GO:0031862 prostanoid receptor binding(GO:0031862)
0.1 0.3 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1 0.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 1.5 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.3 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.6 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 0.2 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1 2.6 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.3 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.7 GO:0039706 co-receptor binding(GO:0039706)
0.1 1.0 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 0.2 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.7 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.1 1.0 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 2.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 1.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 15.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.8 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.1 0.6 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.7 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.1 1.4 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 1.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 2.2 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.3 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 1.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.5 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.3 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 1.0 GO:0070411 I-SMAD binding(GO:0070411)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.9 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 1.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.2 GO:0015403 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) uptake transmembrane transporter activity(GO:0015563)
0.1 0.9 GO:0031005 filamin binding(GO:0031005)
0.1 0.9 GO:0016849 phosphorus-oxygen lyase activity(GO:0016849)
0.1 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.2 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.9 GO:0070513 death domain binding(GO:0070513)
0.0 0.3 GO:0019863 IgE binding(GO:0019863)
0.0 0.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0017153 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 1.1 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0 0.3 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.8 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 2.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 1.1 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 1.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 2.4 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.7 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.4 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.5 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 1.0 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 6.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.7 GO:0045499 chemorepellent activity(GO:0045499)
0.0 5.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.9 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.0 GO:0016409 palmitoyltransferase activity(GO:0016409)
0.0 0.5 GO:0005542 folic acid binding(GO:0005542)
0.0 1.7 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.0 0.1 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.8 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 2.0 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.0 0.3 GO:0016502 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0 2.7 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 2.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.3 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.6 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.0 0.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.3 GO:0043621 protein self-association(GO:0043621)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 1.1 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 2.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 29.4 GO:0001071 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 2.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.3 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0004645 phosphorylase activity(GO:0004645)
0.0 1.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 1.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.6 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.0 0.3 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.6 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.2 GO:0035591 signaling adaptor activity(GO:0035591)
0.0 0.6 GO:0020037 heme binding(GO:0020037)
0.0 0.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.3 0.7 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.3 42.7 PID CMYB PATHWAY C-MYB transcription factor network
0.2 0.7 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.2 22.8 PID IL12 2PATHWAY IL12-mediated signaling events
0.2 3.9 PID IL5 PATHWAY IL5-mediated signaling events
0.2 13.3 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.2 8.0 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.2 15.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.2 3.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 4.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 1.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 4.4 PID IL3 PATHWAY IL3-mediated signaling events
0.2 6.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 5.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.2 1.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 0.6 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 3.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.1 1.0 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 2.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 1.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 14.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 5.6 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 2.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 3.5 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.1 4.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 2.4 PID IFNG PATHWAY IFN-gamma pathway
0.1 0.4 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.1 1.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.1 2.9 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 1.3 PID BCR 5PATHWAY BCR signaling pathway
0.1 1.8 PID MYC PATHWAY C-MYC pathway
0.1 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 0.9 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 2.2 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.5 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 1.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 3.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.8 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.0 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.5 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 1.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 6.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.2 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.8 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID AURORA A PATHWAY Aurora A signaling
0.0 0.2 PID SHP2 PATHWAY SHP2 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 30.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
1.7 10.5 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
1.2 12.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.5 33.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.5 6.0 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.5 11.0 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.5 11.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.4 3.0 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.4 9.3 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.4 15.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.3 8.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.3 3.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.2 2.4 REACTOME DEFENSINS Genes involved in Defensins
0.2 8.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.2 4.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.2 3.2 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.2 3.0 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.2 4.8 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.2 1.2 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2 3.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.2 4.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 2.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 2.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 7.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 4.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 2.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 13.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.1 3.9 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 1.8 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 4.1 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 25.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.1 3.0 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.1 3.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 3.0 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 1.4 REACTOME OPSINS Genes involved in Opsins
0.1 2.8 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.1 1.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 4.6 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 2.1 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 2.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 1.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 6.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 1.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 0.8 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 2.2 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 1.9 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 5.3 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.0 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.6 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.1 0.8 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 3.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.1 1.2 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.1 2.1 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.1 2.4 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.1 3.4 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.1 1.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.9 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 0.9 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 6.3 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 1.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 3.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.6 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1 0.8 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 7.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 1.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 3.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 0.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 1.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 2.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 3.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 4.4 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.1 1.4 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 1.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 1.4 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 1.5 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 1.0 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 6.2 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.5 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 1.6 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 0.9 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 12.9 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 2.2 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.1 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP