Project

avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

Navigation
Downloads

Results for DPRX

Z-value: 2.48

Motif logo

Transcription factors associated with DPRX

Gene Symbol Gene ID Gene Info
ENSG00000204595.1 DPRX

Activity profile of DPRX motif

Sorted Z-values of DPRX motif

Network of associatons between targets according to the STRING database.

First level regulatory network of DPRX

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image
Promoter Score Transcript Gene Gene Info
chr11_+_63681444 11.39 ENST00000341307.6
ENST00000356000.7
ENST00000542238.5
reticulon 3
chr11_+_63681483 10.95 ENST00000339997.8
ENST00000540798.5
ENST00000545432.5
ENST00000543552.5
ENST00000377819.10
ENST00000537981.5
reticulon 3
chr6_-_83709141 10.81 ENST00000521743.5
synaptosome associated protein 91
chr20_+_10218808 10.51 ENST00000254976.7
ENST00000304886.6
synaptosome associated protein 25
chr6_-_83709019 10.34 ENST00000519779.5
ENST00000369694.6
ENST00000195649.10
synaptosome associated protein 91
chr1_+_84181630 9.93 ENST00000610457.1
protein kinase cAMP-activated catalytic subunit beta
chr8_-_119592954 9.32 ENST00000522167.5
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr7_+_150567382 9.22 ENST00000255945.4
ENST00000479232.1
GTPase, IMAP family member 4
chr3_-_18424533 8.83 ENST00000417717.6
SATB homeobox 1
chr1_+_35557768 8.65 ENST00000356090.8
ENST00000373243.7
neurochondrin
chr3_-_18425295 8.36 ENST00000338745.11
ENST00000450898.1
SATB homeobox 1
chr10_-_70602687 8.09 ENST00000638674.1
perforin 1
chr10_-_70602731 7.94 ENST00000441259.2
perforin 1
chr10_-_70602759 7.59 ENST00000373209.2
perforin 1
chr19_+_40778216 7.55 ENST00000594800.5
ENST00000357052.8
ENST00000602173.5
RAB4B, member RAS oncogene family
chr4_-_86453075 7.47 ENST00000641384.1
ENST00000642009.1
ENST00000641274.1
ENST00000641629.1
ENST00000641718.1
ENST00000641782.1
ENST00000511328.5
ENST00000503911.5
ENST00000641862.1
ENST00000640445.1
ENST00000641675.1
ENST00000361569.8
ENST00000639989.2
ENST00000641120.1
ENST00000642023.1
ENST00000641902.1
ENST00000641016.1
ENST00000509464.7
ENST00000638946.2
ENST00000395160.9
ENST00000512017.7
ENST00000639972.2
mitogen-activated protein kinase 10
chr4_+_153222402 6.93 ENST00000676335.1
ENST00000675146.1
tripartite motif containing 2
chr4_-_86594037 6.56 ENST00000641050.1
ENST00000641831.1
ENST00000515400.3
ENST00000641391.1
ENST00000641157.1
ENST00000641737.1
ENST00000502302.6
ENST00000640527.1
ENST00000512046.2
ENST00000513186.7
mitogen-activated protein kinase 10
chr8_-_109644766 6.42 ENST00000533065.5
ENST00000276646.14
syntabulin
chr1_+_110873135 6.42 ENST00000271324.6
CD53 molecule
chr14_+_91114667 6.01 ENST00000523894.5
ENST00000522322.5
ENST00000523771.5
D-glutamate cyclase
chr14_+_22462932 5.93 ENST00000390477.2
T cell receptor delta constant
chr4_+_153222307 5.69 ENST00000675899.1
ENST00000675611.1
ENST00000674872.1
ENST00000676167.1
tripartite motif containing 2
chr3_+_186996444 5.66 ENST00000676633.1
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr10_-_71851239 5.19 ENST00000394936.8
prosaposin
chr19_+_2476118 5.14 ENST00000215631.9
ENST00000587345.1
growth arrest and DNA damage inducible beta
chr12_-_9760893 5.06 ENST00000228434.7
ENST00000536709.1
CD69 molecule
chr7_+_150567347 5.01 ENST00000461940.5
GTPase, IMAP family member 4
chrX_+_101078861 4.76 ENST00000372930.5
transmembrane protein 35A
chr21_-_32727889 4.72 ENST00000630077.3
ENST00000674204.1
synaptojanin 1
chr2_+_119759875 4.66 ENST00000263708.7
protein tyrosine phosphatase non-receptor type 4
chr16_-_18358582 4.60 ENST00000327792.6
nuclear pore complex interacting protein family, member A9
chr3_+_10026409 4.54 ENST00000287647.7
ENST00000676013.1
ENST00000675286.1
ENST00000419585.5
FA complementation group D2
chr20_-_51768327 4.53 ENST00000311637.9
ENST00000338821.6
ATPase phospholipid transporting 9A (putative)
chr6_+_31587268 4.48 ENST00000396101.7
ENST00000490742.5
leukocyte specific transcript 1
chr5_+_35856883 4.39 ENST00000506850.5
ENST00000303115.8
ENST00000511982.1
interleukin 7 receptor
chr14_-_100568070 4.37 ENST00000557378.6
ENST00000443071.6
ENST00000637646.1
brain enriched guanylate kinase associated
chr5_+_140966466 4.32 ENST00000615316.1
ENST00000289269.7
protocadherin alpha subfamily C, 2
chr12_+_57745017 4.31 ENST00000547992.5
ENST00000552816.5
ENST00000257910.8
ENST00000547472.5
tetraspanin 31
chr3_+_40309678 4.30 ENST00000232905.4
eukaryotic translation initiation factor 1B
chr2_+_183078736 4.23 ENST00000354221.5
dual specificity phosphatase 19
chr10_+_93757831 4.19 ENST00000629035.2
leucine rich glioma inactivated 1
chr11_-_6419394 4.11 ENST00000311051.7
amyloid beta precursor protein binding family B member 1
chr3_+_159273235 4.10 ENST00000638749.1
IQCJ-SCHIP1 readthrough
chr9_+_2015186 4.04 ENST00000357248.8
ENST00000450198.6
ENST00000634287.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_+_113049616 3.97 ENST00000504454.5
ENST00000357077.9
ENST00000394537.7
ENST00000672779.1
ENST00000264366.10
ankyrin 2
chr4_-_86358487 3.94 ENST00000641066.1
ENST00000512689.6
ENST00000641803.1
ENST00000640970.1
ENST00000641983.1
mitogen-activated protein kinase 10
chr2_-_85328262 3.85 ENST00000282120.6
trans-golgi network protein 2
chr2_-_85328232 3.80 ENST00000398263.6
trans-golgi network protein 2
chr12_-_101830926 3.73 ENST00000299314.12
N-acetylglucosamine-1-phosphate transferase subunits alpha and beta
chr14_-_100568475 3.70 ENST00000553553.6
brain enriched guanylate kinase associated
chr3_+_4680617 3.61 ENST00000648212.1
inositol 1,4,5-trisphosphate receptor type 1
chr9_+_2015335 3.53 ENST00000636559.1
ENST00000349721.8
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr5_-_142685654 3.50 ENST00000378046.5
ENST00000619447.4
fibroblast growth factor 1
chr16_+_16350098 3.47 ENST00000331436.6
novel member of the nuclear pore complex interacting protein NPIP gene family
chr11_+_61755372 3.46 ENST00000265460.9
myelin regulatory factor
chr9_+_2110354 3.43 ENST00000634772.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_-_170074568 3.40 ENST00000367767.5
ENST00000361580.7
ENST00000538366.5
kinesin associated protein 3
chr11_-_105035113 3.33 ENST00000526568.5
ENST00000531166.5
ENST00000534497.5
ENST00000527979.5
ENST00000533400.6
ENST00000528974.1
ENST00000525825.5
ENST00000353247.9
ENST00000446369.5
ENST00000436863.7
caspase 1
chr12_+_93378625 3.24 ENST00000546925.1
nudix hydrolase 4
chr19_+_8413270 3.19 ENST00000381035.8
ENST00000595142.5
ENST00000601724.5
ENST00000601283.5
ENST00000215555.7
ENST00000595213.1
membrane associated ring-CH-type finger 2
chr20_-_35742207 3.19 ENST00000397370.3
ENST00000528062.7
ENST00000374038.7
ENST00000253363.11
ENST00000361162.10
RNA binding motif protein 39
chr1_+_50103903 3.17 ENST00000371827.5
ELAV like RNA binding protein 4
chr14_-_24442241 3.09 ENST00000555355.5
ENST00000553343.5
ENST00000556523.1
ENST00000556249.1
ENST00000538105.6
ENST00000555225.5
short chain dehydrogenase/reductase family 39U member 1
chr16_+_21233672 3.07 ENST00000311620.7
ankyrin repeat and sterile alpha motif domain containing 4B
chr6_+_157381133 2.93 ENST00000414563.6
ENST00000359775.10
zinc finger DHHC-type palmitoyltransferase 14
chr7_-_98252117 2.93 ENST00000420697.1
ENST00000415086.5
ENST00000447648.7
tectonin beta-propeller repeat containing 1
chr15_-_34437769 2.93 ENST00000359187.5
golgin A8 family member A
chr11_+_2302119 2.92 ENST00000381121.7
tetraspanin 32
chr6_-_33322803 2.78 ENST00000446511.1
ENST00000446403.1
ENST00000374542.10
ENST00000266000.10
ENST00000414083.6
ENST00000620164.4
death domain associated protein
chr16_+_81238682 2.75 ENST00000258168.7
ENST00000564552.1
beta-carotene oxygenase 1
chr13_-_44474296 2.71 ENST00000611198.4
TSC22 domain family member 1
chr11_-_56292254 2.68 ENST00000641600.1
olfactory receptor family 8 subfamily H member 1
chr16_-_21405319 2.67 ENST00000542817.1
nuclear pore complex interacting protein family member B3
chr16_-_21837770 2.66 ENST00000537951.1
nuclear pore complex interacting protein family member B4
chr11_-_2301859 2.65 ENST00000456145.2
ENST00000381153.8
chromosome 11 open reading frame 21
chr22_+_39077264 2.64 ENST00000407997.4
apolipoprotein B mRNA editing enzyme catalytic subunit 3G
chr7_-_135728177 2.58 ENST00000682651.1
ENST00000354042.8
solute carrier family 13 member 4
chr19_-_3772211 2.57 ENST00000555978.5
ENST00000555633.3
retina and anterior neural fold homeobox 2
chr18_+_58862904 2.52 ENST00000591083.5
zinc finger protein 532
chr5_+_141370236 2.49 ENST00000576222.2
ENST00000618934.1
protocadherin gamma subfamily B, 3
chr7_+_5190273 2.49 ENST00000382384.6
WD repeat domain, phosphoinositide interacting 2
chr1_-_27155118 2.44 ENST00000263980.8
solute carrier family 9 member A1
chr2_+_112584586 2.41 ENST00000409719.1
coiled-coil-helix-coiled-coil-helix domain containing 5
chr6_-_32763522 2.39 ENST00000435145.6
ENST00000437316.7
major histocompatibility complex, class II, DQ beta 2
chr11_-_85665077 2.34 ENST00000527447.2
CREB/ATF bZIP transcription factor
chr9_+_17135017 2.32 ENST00000380641.4
ENST00000380647.8
centlein
chr1_-_143905966 2.26 ENST00000609879.2
ENST00000392948.5
H3.2 histone (putative)
chr3_-_32570771 2.25 ENST00000273130.9
ENST00000432458.6
ENST00000424991.1
dynein cytoplasmic 1 light intermediate chain 1
chr15_+_81182579 2.24 ENST00000302987.9
interleukin 16
chr5_+_112737847 2.24 ENST00000257430.9
ENST00000508376.6
APC regulator of WNT signaling pathway
chr17_-_15265230 2.24 ENST00000676161.1
ENST00000646419.2
ENST00000312280.9
ENST00000494511.7
ENST00000580584.3
ENST00000676221.1
peripheral myelin protein 22
chr7_+_90346679 2.21 ENST00000417207.5
ENST00000222511.11
GTP binding protein 10
chrX_+_15749848 2.20 ENST00000479740.5
ENST00000454127.2
carbonic anhydrase 5B
chr16_-_15856994 2.20 ENST00000576790.7
ENST00000396324.7
ENST00000300036.6
ENST00000452625.7
myosin heavy chain 11
chr9_-_13279407 2.15 ENST00000546205.5
multiple PDZ domain crumbs cell polarity complex component
chr1_-_45339995 2.14 ENST00000488731.6
ENST00000435155.1
mutY DNA glycosylase
chr19_-_12723925 2.13 ENST00000425528.6
ENST00000589337.5
ENST00000588216.5
transportin 2
chr12_-_113136224 2.13 ENST00000546530.5
ENST00000261729.9
RAS protein activator like 1
chr7_+_90346665 2.10 ENST00000257659.12
GTP binding protein 10
chr6_-_32816910 2.09 ENST00000447394.1
ENST00000438763.7
major histocompatibility complex, class II, DO beta
chr18_+_44680875 2.08 ENST00000649279.2
ENST00000677699.1
SET binding protein 1
chr8_-_144475808 2.07 ENST00000377317.5
forkhead box H1
chr16_-_33845229 2.07 ENST00000569103.2
immunoglobulin heavy variable 3/OR16-17 (non-functional)
chr17_-_19867929 2.05 ENST00000361658.6
ENST00000395544.9
unc-51 like autophagy activating kinase 2
chrX_+_101623121 2.03 ENST00000491568.6
ENST00000479298.5
ENST00000471229.7
armadillo repeat containing X-linked 3
chr17_-_28897724 2.03 ENST00000394908.9
flotillin 2
chr2_-_159798043 2.02 ENST00000664982.1
ENST00000259053.6
novel transcript, sense intronic to CD302and LY75-CD302
CD302 molecule
chr8_-_30812773 2.01 ENST00000221138.9
protein phosphatase 2 catalytic subunit beta
chr6_-_32941018 2.00 ENST00000418107.3
major histocompatibility complex, class II, DM beta
chr15_+_33310946 1.99 ENST00000415757.7
ENST00000634891.2
ENST00000389232.9
ENST00000622037.1
ryanodine receptor 3
chr12_+_54497712 1.99 ENST00000293373.11
NCK associated protein 1 like
chrX_-_33211540 1.96 ENST00000357033.9
dystrophin
chr10_-_101818425 1.95 ENST00000361464.8
ENST00000439817.5
O-GlcNAcase
chr14_-_106762576 1.94 ENST00000624687.1
immunoglobulin heavy variable 1-69D
chr11_-_35418966 1.90 ENST00000531628.2
solute carrier family 1 member 2
chr1_+_13892791 1.90 ENST00000636564.1
ENST00000636203.1
kazrin, periplakin interacting protein
chr1_+_19312341 1.89 ENST00000400548.6
solute carrier family 66 member 1
chr2_-_159798234 1.86 ENST00000429078.6
ENST00000553424.5
CD302 molecule
chr17_-_8383164 1.86 ENST00000584164.6
ENST00000582556.5
ENST00000648839.1
ENST00000578812.5
ENST00000583011.6
ribosomal protein L26
chr1_-_45339935 1.83 ENST00000372104.5
ENST00000448481.5
ENST00000483127.1
ENST00000528013.6
ENST00000456914.7
mutY DNA glycosylase
chr16_-_67393486 1.82 ENST00000562206.1
ENST00000393957.7
ENST00000290942.9
tubulin polymerization promoting protein family member 3
chr7_+_139829153 1.79 ENST00000652056.1
thromboxane A synthase 1
chr2_-_25252072 1.79 ENST00000683760.1
DNA methyltransferase 3 alpha
chr1_+_19312296 1.77 ENST00000375155.7
ENST00000375153.8
solute carrier family 66 member 1
chr9_-_13279564 1.77 ENST00000541718.5
ENST00000447879.6
multiple PDZ domain crumbs cell polarity complex component
chr2_-_25252251 1.72 ENST00000380746.8
ENST00000402667.1
DNA methyltransferase 3 alpha
chr12_+_132986359 1.68 ENST00000328654.10
zinc finger protein 26
chr17_-_28897602 1.67 ENST00000394906.6
ENST00000585169.5
flotillin 2
chr19_+_10420474 1.65 ENST00000380702.7
phosphodiesterase 4A
chr18_-_67516707 1.65 ENST00000310045.9
dermatan sulfate epimerase like
chr8_+_47260922 1.61 ENST00000518074.5
ENST00000297423.9
ENST00000524006.5
scaffold protein involved in DNA repair
chr14_-_106715166 1.60 ENST00000390633.2
immunoglobulin heavy variable 1-69
chr4_+_158210479 1.59 ENST00000504569.5
ENST00000509278.5
ENST00000514558.5
ENST00000503200.5
ENST00000296529.11
transmembrane protein 144
chr1_+_20070156 1.57 ENST00000375108.4
phospholipase A2 group V
chr11_-_35419462 1.54 ENST00000643522.1
solute carrier family 1 member 2
chr1_+_202348687 1.52 ENST00000608999.6
ENST00000391959.5
ENST00000480184.5
protein phosphatase 1 regulatory subunit 12B
chr17_-_39401593 1.48 ENST00000394294.7
ENST00000264658.11
ENST00000583610.5
ENST00000647139.1
F-box and leucine rich repeat protein 20
chr12_-_70788914 1.47 ENST00000342084.8
protein tyrosine phosphatase receptor type R
chr11_-_35419098 1.47 ENST00000606205.6
ENST00000645303.1
solute carrier family 1 member 2
chr14_+_85530127 1.43 ENST00000330753.6
fibronectin leucine rich transmembrane protein 2
chr7_+_5190196 1.42 ENST00000401525.7
ENST00000288828.9
ENST00000404704.7
WD repeat domain, phosphoinositide interacting 2
chr8_-_30812867 1.42 ENST00000518243.5
protein phosphatase 2 catalytic subunit beta
chr11_+_96389985 1.41 ENST00000332349.5
JRK like
chr9_+_113444725 1.40 ENST00000374140.6
regulator of G protein signaling 3
chr11_-_35419213 1.35 ENST00000642171.1
ENST00000644050.1
ENST00000643134.1
solute carrier family 1 member 2
chr11_-_35419542 1.34 ENST00000643305.1
ENST00000644351.1
ENST00000278379.9
ENST00000644779.1
solute carrier family 1 member 2
chr14_+_85533167 1.27 ENST00000682132.1
fibronectin leucine rich transmembrane protein 2
chrX_-_3713593 1.27 ENST00000262848.6
protein kinase X-linked
chr19_-_50025936 1.26 ENST00000596445.5
ENST00000599538.5
VRK serine/threonine kinase 3
chr11_-_61967127 1.23 ENST00000532601.1
ferritin heavy chain 1
chr19_+_49496424 1.23 ENST00000596873.1
ENST00000594493.1
ENST00000270625.7
ENST00000599561.1
ribosomal protein S11
chr21_+_42653585 1.22 ENST00000291539.11
phosphodiesterase 9A
chr3_+_51942323 1.21 ENST00000431474.6
ENST00000417220.6
ENST00000398755.8
ENST00000471971.6
poly(ADP-ribose) polymerase family member 3
chr11_+_65576023 1.20 ENST00000533237.5
ENST00000309295.9
ENST00000634639.1
EH domain binding protein 1 like 1
chr19_+_35648286 1.19 ENST00000649813.2
cytochrome c oxidase subunit 6B1
chr11_-_96389857 1.17 ENST00000680532.1
ENST00000681014.1
ENST00000679708.1
ENST00000645439.1
ENST00000645366.1
ENST00000680728.1
ENST00000680859.1
ENST00000679788.1
ENST00000681164.1
ENST00000646818.2
ENST00000680171.1
ENST00000679696.1
ENST00000681200.1
ENST00000679960.1
ENST00000647080.1
ENST00000646050.1
ENST00000681451.1
ENST00000644686.1
ENST00000680052.1
ENST00000679616.1
ENST00000530203.2
coiled-coil domain containing 82
chr11_+_2301987 1.16 ENST00000612299.4
ENST00000182290.9
tetraspanin 32
chr1_-_13347134 1.16 ENST00000334600.7
PRAME family member 14
chrX_-_139642835 1.15 ENST00000536274.5
MCF.2 cell line derived transforming sequence
chr21_-_36990198 1.10 ENST00000427746.1
ENST00000336648.8
holocarboxylase synthetase
chr1_+_16440700 1.10 ENST00000504551.6
ENST00000457722.6
ENST00000337132.10
ENST00000443980.6
NECAP endocytosis associated 2
chr19_-_49867542 1.10 ENST00000600910.5
ENST00000322344.8
ENST00000600573.5
ENST00000596726.3
ENST00000638016.1
polynucleotide kinase 3'-phosphatase
chr9_+_98943705 1.09 ENST00000610452.1
collagen type XV alpha 1 chain
chr11_-_66907891 1.07 ENST00000393955.6
pyruvate carboxylase
chr2_+_33436304 1.04 ENST00000402538.7
RAS guanyl releasing protein 3
chr1_+_36307090 1.03 ENST00000505871.7
SH3 domain containing 21
chr19_+_55654115 0.99 ENST00000450554.6
U2 small nuclear RNA auxiliary factor 2
chrX_-_139642889 0.99 ENST00000370576.9
MCF.2 cell line derived transforming sequence
chr19_+_40717091 0.98 ENST00000263370.3
inositol-trisphosphate 3-kinase C
chr18_+_13465009 0.98 ENST00000593236.1
ENST00000678400.1
low density lipoprotein receptor class A domain containing 4
chr3_+_130931893 0.98 ENST00000504612.5
ATPase secretory pathway Ca2+ transporting 1
chr6_+_70667863 0.97 ENST00000370455.8
small ArfGAP 1
chr16_+_28711417 0.96 ENST00000395587.5
ENST00000569690.5
ENST00000331666.11
ENST00000564243.5
ENST00000566866.5
eukaryotic translation initiation factor 3 subunit C
chr19_-_43619591 0.96 ENST00000598676.1
ENST00000300811.8
zinc finger protein 428
chr10_-_46023445 0.92 ENST00000585132.5
nuclear receptor coactivator 4
chr17_-_39225936 0.91 ENST00000333461.6
SH3 and cysteine rich domain 2
chr7_+_66114814 0.89 ENST00000431089.6
ENST00000398684.6
ENST00000395326.8
ENST00000338592.5
CGRP receptor component
chr6_-_32763466 0.89 ENST00000427449.1
ENST00000411527.5
major histocompatibility complex, class II, DQ beta 2
chr16_-_28403841 0.88 ENST00000398944.7
ENST00000380876.5
eukaryotic translation initiation factor 3 subunit C like
chr14_+_61529005 0.87 ENST00000556347.1
novel protein
chr5_+_140401808 0.85 ENST00000616482.4
ENST00000297183.10
ENST00000360839.7
ENST00000421134.5
ENST00000394723.7
ENST00000511151.5
ankyrin repeat and KH domain containing 1
chrX_-_111410420 0.84 ENST00000371993.7
ENST00000680476.1
doublecortin
chr18_-_69947864 0.84 ENST00000582621.6
CD226 molecule
chr1_-_42740140 0.84 ENST00000372539.3
ENST00000296387.6
ENST00000539749.5
claudin 19
chr1_+_28812160 0.83 ENST00000234961.7
opioid receptor delta 1
chr1_-_100249815 0.82 ENST00000370131.3
ENST00000681617.1
ENST00000681780.1
ENST00000370132.8
dihydrolipoamide branched chain transacylase E2
chr15_-_52569126 0.80 ENST00000569723.5
ENST00000567669.5
ENST00000569281.6
ENST00000563566.5
ENST00000567830.1
cAMP regulated phosphoprotein 19
chr9_-_92482350 0.79 ENST00000375543.2
asporin
chr1_+_11691688 0.79 ENST00000294485.6
dorsal inhibitory axon guidance protein
chr1_-_13201409 0.77 ENST00000625019.3
PRAME family member 13
chr22_-_38084093 0.76 ENST00000681075.1
solute carrier family 16 member 8
chrX_-_32412220 0.75 ENST00000619831.5
dystrophin
chr17_-_75667165 0.75 ENST00000584999.1
ENST00000420326.6
ENST00000340830.9
RecQ like helicase 5
chr11_-_102705737 0.75 ENST00000260229.5
matrix metallopeptidase 27
chr18_+_7754959 0.74 ENST00000400053.8
protein tyrosine phosphatase receptor type M
chr1_-_184974477 0.73 ENST00000367511.4
niban apoptosis regulator 1
chr1_+_12773738 0.73 ENST00000357726.5
PRAME family member 12
chr15_-_52569197 0.72 ENST00000563277.5
ENST00000566423.5
cAMP regulated phosphoprotein 19
chr2_-_26478032 0.72 ENST00000338581.10
ENST00000402415.8
otoferlin

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 23.6 GO:0002357 defense response to tumor cell(GO:0002357)
2.2 22.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
2.1 10.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
1.7 9.9 GO:0097338 response to clozapine(GO:0097338)
1.4 4.1 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
1.3 19.2 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
1.2 3.7 GO:0016256 N-glycan processing to lysosome(GO:0016256)
1.2 18.0 GO:0007258 JUN phosphorylation(GO:0007258)
1.2 4.7 GO:1904980 positive regulation of endosome organization(GO:1904980)
1.1 3.4 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
1.1 3.3 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
1.0 4.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.8 2.4 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092) positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.8 3.9 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.7 2.2 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.7 21.1 GO:0048268 clathrin coat assembly(GO:0048268)
0.7 2.1 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.7 2.0 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.7 2.0 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
0.6 9.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638) positive regulation of lamellipodium morphogenesis(GO:2000394)
0.6 3.1 GO:1904970 brush border assembly(GO:1904970)
0.6 3.5 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.6 4.0 GO:0045007 depurination(GO:0045007)
0.5 3.2 GO:0070383 DNA cytosine deamination(GO:0070383)
0.5 2.1 GO:0035054 embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.5 7.6 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.5 3.5 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.5 4.4 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.5 2.8 GO:1903936 cellular response to sodium arsenite(GO:1903936)
0.5 3.7 GO:0044860 protein localization to plasma membrane raft(GO:0044860)
0.5 4.5 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.4 2.8 GO:0072757 cellular response to camptothecin(GO:0072757)
0.4 3.6 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.4 4.0 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.4 1.6 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.4 1.5 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.3 7.7 GO:0006895 Golgi to endosome transport(GO:0006895)
0.3 3.5 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.3 3.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.3 5.7 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.3 0.8 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.3 2.2 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.3 1.1 GO:0009305 protein biotinylation(GO:0009305) histone biotinylation(GO:0071110)
0.3 0.8 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.3 1.1 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.3 1.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.3 1.9 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.3 2.6 GO:0008272 sulfate transport(GO:0008272)
0.2 0.5 GO:1904732 regulation of electron carrier activity(GO:1904732)
0.2 2.6 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.2 2.3 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.2 5.1 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.2 6.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.2 4.9 GO:0060736 prostate gland growth(GO:0060736)
0.2 4.2 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.2 2.7 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.2 2.7 GO:0006776 vitamin A metabolic process(GO:0006776)
0.2 2.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.2 0.5 GO:2001033 negative regulation of double-strand break repair via nonhomologous end joining(GO:2001033)
0.2 1.2 GO:0006880 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.2 1.0 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.2 0.5 GO:0071529 cementum mineralization(GO:0071529)
0.2 2.3 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 4.4 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 0.6 GO:0045356 toll-like receptor 7 signaling pathway(GO:0034154) positive regulation of interferon-alpha biosynthetic process(GO:0045356)
0.1 2.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 0.5 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 2.2 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 0.7 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 1.5 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.1 0.9 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 2.2 GO:0032060 bleb assembly(GO:0032060)
0.1 1.0 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.1 2.0 GO:0018345 protein palmitoylation(GO:0018345)
0.1 8.6 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 0.3 GO:0051877 pigment granule aggregation in cell center(GO:0051877)
0.1 6.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 1.8 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 5.6 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.1 1.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.1 11.0 GO:0007286 spermatid development(GO:0007286)
0.1 2.9 GO:0097352 autophagosome maturation(GO:0097352)
0.1 6.4 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.1 0.5 GO:0021798 forebrain dorsal/ventral pattern formation(GO:0021798)
0.1 1.2 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.1 1.6 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.1 1.0 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.8 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.8 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 0.7 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 6.4 GO:0046323 glucose import(GO:0046323)
0.1 1.2 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.3 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 1.1 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.1 1.7 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 4.5 GO:0050672 negative regulation of mononuclear cell proliferation(GO:0032945) negative regulation of lymphocyte proliferation(GO:0050672)
0.0 1.3 GO:2000696 regulation of epithelial cell differentiation involved in kidney development(GO:2000696)
0.0 1.3 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.0 0.1 GO:0001545 primary ovarian follicle growth(GO:0001545)
0.0 2.2 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.7 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 1.5 GO:0001662 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.0 0.7 GO:0006349 regulation of gene expression by genetic imprinting(GO:0006349)
0.0 0.8 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.7 GO:0010842 retina layer formation(GO:0010842)
0.0 1.0 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 0.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 9.3 GO:0043523 regulation of neuron apoptotic process(GO:0043523)
0.0 2.0 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 1.0 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 2.2 GO:0031295 T cell costimulation(GO:0031295)
0.0 1.0 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 2.3 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.0 0.8 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 1.8 GO:0046785 microtubule polymerization(GO:0046785)
0.0 4.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 4.2 GO:0030307 positive regulation of cell growth(GO:0030307)
0.0 2.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 2.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.5 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.3 GO:0008212 androgen biosynthetic process(GO:0006702) estrogen biosynthetic process(GO:0006703) mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
0.0 0.7 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.0 1.8 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.6 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.5 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.0 0.1 GO:0015742 alpha-ketoglutarate transport(GO:0015742)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 10.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
2.4 23.6 GO:0044194 cytolytic granule(GO:0044194)
1.1 3.4 GO:0016939 kinesin II complex(GO:0016939)
1.1 3.3 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.8 3.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.7 7.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.5 20.7 GO:0005720 nuclear heterochromatin(GO:0005720)
0.5 9.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.5 4.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.4 6.4 GO:0097433 dense body(GO:0097433)
0.4 2.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.4 7.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.4 8.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.3 3.6 GO:0005955 calcineurin complex(GO:0005955)
0.3 11.0 GO:0016514 SWI/SNF complex(GO:0016514) npBAF complex(GO:0071564)
0.3 1.2 GO:0008043 intracellular ferritin complex(GO:0008043) ferritin complex(GO:0070288)
0.2 5.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 27.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.2 3.7 GO:0016600 flotillin complex(GO:0016600)
0.2 2.7 GO:0016013 syntrophin complex(GO:0016013)
0.2 3.9 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.2 1.0 GO:0089701 U2AF(GO:0089701)
0.2 2.2 GO:1990909 Wnt signalosome(GO:1990909)
0.2 0.9 GO:0044754 autolysosome(GO:0044754)
0.2 1.8 GO:0097427 microtubule bundle(GO:0097427)
0.2 0.8 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2 7.6 GO:0030673 axolemma(GO:0030673)
0.2 2.2 GO:0043218 compact myelin(GO:0043218)
0.2 2.0 GO:0031209 SCAR complex(GO:0031209)
0.2 8.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 2.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.6 GO:0036020 endolysosome membrane(GO:0036020)
0.1 0.7 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.5 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 2.9 GO:0000421 autophagosome membrane(GO:0000421)
0.1 1.1 GO:0098651 basement membrane collagen trimer(GO:0098651)
0.1 6.4 GO:0001772 immunological synapse(GO:0001772)
0.1 2.4 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.1 4.0 GO:0031430 M band(GO:0031430)
0.1 2.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 7.8 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 3.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.3 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 4.1 GO:0008305 integrin complex(GO:0008305)
0.1 7.0 GO:0005902 microvillus(GO:0005902)
0.1 2.2 GO:0032982 myosin filament(GO:0032982)
0.1 1.0 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.5 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 2.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 0.5 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.1 1.8 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 4.1 GO:0035577 azurophil granule membrane(GO:0035577)
0.1 0.9 GO:0042575 DNA polymerase complex(GO:0042575)
0.1 4.8 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.1 1.1 GO:0005652 nuclear lamina(GO:0005652)
0.0 27.1 GO:0000139 Golgi membrane(GO:0000139)
0.0 5.5 GO:0031901 early endosome membrane(GO:0031901)
0.0 10.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 3.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 2.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.9 GO:0031672 A band(GO:0031672)
0.0 2.8 GO:0070603 SWI/SNF superfamily-type complex(GO:0070603)
0.0 0.3 GO:0034464 BBSome(GO:0034464)
0.0 0.8 GO:0032589 neuron projection membrane(GO:0032589)
0.0 3.1 GO:0005814 centriole(GO:0005814)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.4 GO:0030990 intraciliary transport particle(GO:0030990)
0.0 0.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 1.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.6 GO:0032587 ruffle membrane(GO:0032587)
0.0 15.3 GO:0043005 neuron projection(GO:0043005)
0.0 3.2 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.3 9.3 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
1.4 18.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
1.1 5.7 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
1.0 4.0 GO:0032406 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.9 3.7 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.9 23.6 GO:0022829 wide pore channel activity(GO:0022829)
0.8 21.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.7 11.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.7 4.7 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.6 1.8 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.6 3.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.6 5.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.5 1.6 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.5 7.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.5 2.6 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.5 16.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.5 2.6 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.5 3.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.4 4.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.4 5.4 GO:0032395 MHC class II receptor activity(GO:0032395)
0.4 4.7 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.3 2.6 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.3 3.3 GO:0050700 CARD domain binding(GO:0050700)
0.3 1.1 GO:0018271 biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
0.3 1.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.2 1.0 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.2 2.4 GO:0005549 odorant binding(GO:0005549)
0.2 2.4 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) protein phosphatase 2B binding(GO:0030346)
0.2 0.7 GO:0016296 oleoyl-[acyl-carrier-protein] hydrolase activity(GO:0004320) myristoyl-[acyl-carrier-protein] hydrolase activity(GO:0016295) palmitoyl-[acyl-carrier-protein] hydrolase activity(GO:0016296) acyl-[acyl-carrier-protein] hydrolase activity(GO:0016297)
0.2 6.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.2 6.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 0.5 GO:0004618 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
0.2 4.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 2.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.2 1.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.2 2.9 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.2 1.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 4.1 GO:0048156 tau protein binding(GO:0048156)
0.1 0.6 GO:0002046 opsin binding(GO:0002046)
0.1 4.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 1.0 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.1 8.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.7 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 2.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 8.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 1.1 GO:0009374 biotin binding(GO:0009374)
0.1 2.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 2.7 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.1 0.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.8 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 2.0 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.1 5.8 GO:0050681 androgen receptor binding(GO:0050681)
0.1 2.2 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.9 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 2.7 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 4.6 GO:0030507 spectrin binding(GO:0030507)
0.1 3.4 GO:0019894 kinesin binding(GO:0019894)
0.1 0.5 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 3.2 GO:0017091 AU-rich element binding(GO:0017091)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 2.2 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 1.1 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.1 0.3 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 3.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 0.3 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 24.7 GO:0005525 GTP binding(GO:0005525)
0.1 0.8 GO:0004985 opioid receptor activity(GO:0004985)
0.1 17.8 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 1.0 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 3.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 2.1 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.2 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 3.4 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 6.0 GO:0003823 antigen binding(GO:0003823)
0.0 1.2 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 1.5 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 1.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0004963 follicle-stimulating hormone receptor activity(GO:0004963)
0.0 0.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 2.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 1.0 GO:0070412 R-SMAD binding(GO:0070412)
0.0 2.0 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.7 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 6.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.6 GO:0015144 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 4.1 GO:0030246 carbohydrate binding(GO:0030246)
0.0 3.2 GO:0008022 protein C-terminus binding(GO:0008022)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 23.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.4 18.8 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.3 20.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.2 9.9 PID IL3 PATHWAY IL3-mediated signaling events
0.1 5.1 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 12.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 3.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.8 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.1 4.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.1 4.5 PID ATR PATHWAY ATR signaling pathway
0.1 3.2 PID RAS PATHWAY Regulation of Ras family activation
0.1 3.7 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.0 3.5 PID FGF PATHWAY FGF signaling pathway
0.0 2.4 PID RHOA PATHWAY RhoA signaling pathway
0.0 2.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 3.4 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 4.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.6 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 1.1 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 3.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.7 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.1 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.8 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 18.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.5 10.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.4 4.5 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.3 9.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.2 5.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 2.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.2 3.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 18.7 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.2 3.5 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.2 3.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 2.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.1 2.9 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 3.4 REACTOME KINESINS Genes involved in Kinesins
0.1 4.7 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.1 6.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 5.2 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.1 8.0 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.1 2.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 6.8 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 2.1 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.1 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 2.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 2.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 2.7 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 2.7 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 2.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 1.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.0 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.1 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 1.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.5 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins