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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for E2F3

Z-value: 15.22

Motif logo

Transcription factors associated with E2F3

Gene Symbol Gene ID Gene Info
ENSG00000112242.15 E2F3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F3hg38_v1_chr6_+_20403679_20403735,
hg38_v1_chr6_+_20401864_20401921
0.672.5e-29Click!

Activity profile of E2F3 motif

Sorted Z-values of E2F3 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F3

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr17_+_75205659 74.92 ENST00000583569.5
ENST00000245544.9
ENST00000579324.5
ENST00000579298.5
nucleoporin 85
chr15_-_90994494 66.31 ENST00000559811.1
ENST00000442656.6
ENST00000557905.5
ENST00000394249.8
protein regulator of cytokinesis 1
chr6_-_13814490 60.81 ENST00000379170.8
mitochondrial calcium uniporter regulator 1
chr8_-_63038788 53.41 ENST00000518113.2
ENST00000260118.7
ENST00000677482.1
gamma-glutamyl hydrolase
chr7_+_141738321 53.01 ENST00000612337.4
single stranded DNA binding protein 1
chr1_-_8878646 47.45 ENST00000643438.1
enolase 1
chr20_+_25407657 46.61 ENST00000262460.5
GINS complex subunit 1
chr9_-_92293674 46.05 ENST00000683679.1
ENST00000683565.1
ENST00000684557.1
ENST00000682578.1
ENST00000443024.7
ENST00000375643.7
ENST00000683469.1
isoleucyl-tRNA synthetase 1
chr7_+_141738343 45.89 ENST00000498107.5
ENST00000265304.11
ENST00000467681.5
ENST00000465582.5
ENST00000463093.5
single stranded DNA binding protein 1
chr3_+_52705828 45.43 ENST00000233025.11
signal peptidase complex subunit 1
chr8_+_26291758 45.29 ENST00000522535.5
ENST00000665949.1
protein phosphatase 2 regulatory subunit Balpha
chr1_-_8878706 43.52 ENST00000646156.1
enolase 1
chr8_-_27837765 43.27 ENST00000521226.2
ENST00000301905.9
PDZ binding kinase
chr5_+_32585549 43.19 ENST00000265073.9
ENST00000515355.5
ENST00000502897.5
ENST00000510442.1
SUB1 regulator of transcription
chr11_+_32583792 40.15 ENST00000531120.6
ENST00000524896.5
ENST00000323213.9
eukaryotic translation initiation factor 3 subunit M
chr5_+_172958729 39.81 ENST00000519974.5
ENST00000521476.5
ribosomal protein L26 like 1
chr5_-_80654956 39.59 ENST00000439211.7
dihydrofolate reductase
chr16_+_1309714 39.38 ENST00000566587.5
ubiquitin conjugating enzyme E2 I
chr5_+_160421847 39.22 ENST00000352433.10
ENST00000517480.1
ENST00000520452.5
ENST00000393964.1
PTTG1 regulator of sister chromatid separation, securin
chr14_+_51240205 39.10 ENST00000457354.7
thioredoxin related transmembrane protein 1
chr14_+_96797304 39.08 ENST00000553683.2
ENST00000680538.1
ENST00000681195.1
ENST00000679727.1
ENST00000680509.1
ENST00000557222.6
ENST00000680683.1
ENST00000680335.1
ENST00000216639.8
ENST00000679736.1
ENST00000681176.1
ENST00000557352.2
ENST00000679903.1
ENST00000681419.1
ENST00000680849.1
ENST00000681493.1
ENST00000679770.1
ENST00000681355.1
ENST00000681344.1
VRK serine/threonine kinase 1
chr2_-_169824814 39.03 ENST00000409340.5
methyltransferase like 5
chr20_-_62143374 38.46 ENST00000370873.9
ENST00000370858.3
proteasome 20S subunit alpha 7
chr2_-_69437417 38.34 ENST00000450796.6
ENST00000484177.5
ENST00000410022.7
ENST00000303698.7
NFU1 iron-sulfur cluster scaffold
chr20_+_49046246 38.14 ENST00000396192.7
ENST00000262982.3
chromosome segregation 1 like
chr7_-_141014629 37.96 ENST00000393008.7
mitochondrial ribosomal protein S33
chr10_-_56361235 37.94 ENST00000373944.8
ENST00000361148.6
ENST00000395405.5
ZW10 interacting kinetochore protein
chr9_-_109013483 37.78 ENST00000325551.9
ENST00000374593.4
ENST00000374595.8
catenin alpha like 1
chr15_-_66356672 37.15 ENST00000261881.9
TIMELESS interacting protein
chr12_-_50025394 36.90 ENST00000454520.6
ENST00000546595.5
ENST00000548824.5
ENST00000549777.5
ENST00000546723.5
ENST00000427314.6
ENST00000552157.5
ENST00000552310.5
ENST00000548644.5
ENST00000546786.5
ENST00000550149.5
ENST00000546764.5
ENST00000552004.2
ENST00000548320.5
ENST00000312377.10
ENST00000547905.5
ENST00000550651.5
ENST00000551145.5
ENST00000552921.5
Rac GTPase activating protein 1
chr19_+_48993864 36.70 ENST00000595090.6
RuvB like AAA ATPase 2
chr10_+_60778490 36.52 ENST00000448257.6
ENST00000614696.4
cyclin dependent kinase 1
chr7_-_141014939 36.45 ENST00000324787.10
ENST00000467334.1
mitochondrial ribosomal protein S33
chr8_+_81280527 36.15 ENST00000297258.11
fatty acid binding protein 5
chr5_-_80654552 36.11 ENST00000511032.5
ENST00000504396.1
ENST00000505337.5
dihydrofolate reductase
chrX_+_78104229 35.25 ENST00000373316.5
phosphoglycerate kinase 1
chr2_-_69437588 35.00 ENST00000394305.5
NFU1 iron-sulfur cluster scaffold
chrX_+_154762729 34.78 ENST00000620277.4
dyskerin pseudouridine synthase 1
chr5_+_1801387 34.49 ENST00000274137.10
ENST00000469176.1
NADH:ubiquinone oxidoreductase subunit S6
chr1_-_43172504 34.11 ENST00000431635.6
EBNA1 binding protein 2
chr1_-_108244076 33.95 ENST00000415641.8
ENST00000613157.2
NBPF member 4
chr5_+_178204522 33.81 ENST00000506339.5
ENST00000358344.8
ENST00000355836.9
ENST00000514633.5
ENST00000515193.5
ENST00000506259.5
ENST00000504898.5
heterogeneous nuclear ribonucleoprotein A/B
chr5_+_5422665 33.74 ENST00000296564.9
interactor of little elongation complex ELL subunit 1
chr18_-_56651122 33.33 ENST00000590954.5
thioredoxin like 1
chr15_+_48331403 33.22 ENST00000558813.5
ENST00000331200.8
ENST00000558472.5
deoxyuridine triphosphatase
chr2_+_264913 33.10 ENST00000439645.6
ENST00000405233.5
ENST00000272065.10
acid phosphatase 1
chr1_-_8879170 32.55 ENST00000489867.2
enolase 1
chr10_+_123154414 32.06 ENST00000368858.9
BUB3 mitotic checkpoint protein
chr7_-_96709780 32.04 ENST00000623693.3
ENST00000623498.3
ENST00000488005.5
ENST00000413065.5
SEM1 26S proteasome complex subunit
chr10_+_60778331 32.02 ENST00000519078.6
ENST00000316629.8
ENST00000395284.8
cyclin dependent kinase 1
chr2_-_10447771 31.81 ENST00000405333.5
ENST00000443218.1
ornithine decarboxylase 1
chr7_-_87219709 31.54 ENST00000257637.8
transmembrane protein 243
chr6_+_52671080 31.12 ENST00000211314.5
transmembrane protein 14A
chr3_+_52706092 31.09 ENST00000619898.5
signal peptidase complex subunit 1
chr7_+_16646131 30.97 ENST00000415365.5
ENST00000433922.6
ENST00000630952.2
ENST00000258761.8
ENST00000405202.5
basic leucine zipper and W2 domains 2
chr1_+_10399054 30.94 ENST00000270776.13
ENST00000483936.5
phosphogluconate dehydrogenase
chr5_-_62403506 30.42 ENST00000680062.1
DIMT1 rRNA methyltransferase and ribosome maturation factor
chr1_-_8878677 30.37 ENST00000234590.10
ENST00000647408.1
enolase 1
chr11_+_4094775 30.22 ENST00000300738.10
ribonucleotide reductase catalytic subunit M1
chr8_+_90001448 30.15 ENST00000519410.5
ENST00000522161.5
ENST00000220764.7
ENST00000517761.5
ENST00000520227.1
2,4-dienoyl-CoA reductase 1
chr11_+_108121557 30.03 ENST00000299355.10
ENST00000673531.1
ENST00000265838.9
ENST00000672367.1
ENST00000672907.1
ENST00000672354.1
acetyl-CoA acetyltransferase 1
chr15_-_55196899 29.39 ENST00000677147.1
ENST00000260443.9
ENST00000677730.1
ribosomal L24 domain containing 1
chr11_+_118401586 29.35 ENST00000649464.1
ENST00000648261.1
ENST00000300688.8
ENST00000533172.5
ENST00000524422.1
novel protein
ATP synthase membrane subunit g
chr11_+_102347312 29.25 ENST00000621637.1
ENST00000613397.4
baculoviral IAP repeat containing 2
chr19_-_6415684 29.25 ENST00000594496.5
ENST00000594745.5
KH-type splicing regulatory protein
chr1_-_43172244 29.12 ENST00000236051.3
EBNA1 binding protein 2
chr4_-_1712250 29.09 ENST00000318386.8
stem-loop binding protein
chr21_-_33479914 29.07 ENST00000542230.7
transmembrane protein 50B
chr7_-_10940123 28.67 ENST00000339600.6
NDUFA4 mitochondrial complex associated
chr1_+_43974902 28.46 ENST00000532642.5
ENST00000236067.8
ENST00000471859.6
ENST00000472174.7
ATPase H+ transporting V0 subunit b
chr17_+_75261661 28.40 ENST00000579761.5
mitochondrial ribosomal protein S7
chr6_+_36594354 28.30 ENST00000373715.11
serine and arginine rich splicing factor 3
chr7_-_105522264 27.94 ENST00000469408.6
pseudouridine synthase 7
chr10_-_17617235 27.94 ENST00000466335.1
3-hydroxyacyl-CoA dehydratase 1
chr20_-_56392131 27.69 ENST00000422322.5
ENST00000371356.6
ENST00000451915.1
ENST00000347343.6
ENST00000395911.5
ENST00000395915.8
ENST00000395907.5
ENST00000441357.5
ENST00000456249.5
ENST00000420474.5
ENST00000395914.5
ENST00000312783.10
ENST00000395913.7
aurora kinase A
chr14_-_60981034 27.41 ENST00000555420.1
ENST00000261249.7
ENST00000553903.1
tRNA methyltransferase 5
chr13_+_75549477 27.19 ENST00000618773.4
ubiquitin C-terminal hydrolase L3
chr8_-_54101979 26.57 ENST00000618914.4
lysophospholipase 1
chr2_+_264869 26.49 ENST00000272067.10
ENST00000407983.7
acid phosphatase 1
chr13_+_75549734 26.42 ENST00000563635.5
ENST00000377595.8
novel transcript
ubiquitin C-terminal hydrolase L3
chr8_-_81686274 26.10 ENST00000449740.6
ENST00000311489.8
ENST00000521360.5
ENST00000519964.5
ENST00000256108.10
ENST00000518202.5
inositol monophosphatase 1
chr16_-_46621345 26.05 ENST00000303383.8
SHC binding and spindle associated 1
chr14_-_49688201 25.83 ENST00000553805.2
ENST00000554396.5
ENST00000216367.10
DNA polymerase epsilon 2, accessory subunit
chr8_-_80029904 25.81 ENST00000521434.5
ENST00000519120.1
ENST00000520946.1
mitochondrial ribosomal protein S28
chr4_-_1712310 25.78 ENST00000488267.5
ENST00000429429.6
ENST00000489418.6
ENST00000480936.1
stem-loop binding protein
chr6_-_38703066 25.77 ENST00000373365.5
glyoxalase I
chr1_+_155208690 25.62 ENST00000368376.8
metaxin 1
chr8_-_80029826 25.42 ENST00000519386.5
mitochondrial ribosomal protein S28
chr11_+_18394552 25.26 ENST00000543445.5
ENST00000430553.6
ENST00000396222.6
ENST00000535451.5
ENST00000422447.8
lactate dehydrogenase A
chr7_+_73683588 25.09 ENST00000265758.7
ENST00000441822.5
ENST00000423497.5
BUD23 rRNA methyltransferase and ribosome maturation factor
chr18_+_22933321 24.86 ENST00000327155.10
RB binding protein 8, endonuclease
chr19_-_42302292 24.82 ENST00000594989.5
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr1_+_75724597 24.76 ENST00000681790.1
acyl-CoA dehydrogenase medium chain
chr12_+_93467506 24.74 ENST00000549982.6
ENST00000552217.6
ENST00000393128.8
ENST00000547098.5
mitochondrial ribosomal protein L42
chr7_-_105522204 24.71 ENST00000356362.6
pseudouridine synthase 7
chr1_-_246566238 24.58 ENST00000366514.5
transcription factor B2, mitochondrial
chr2_-_86195400 24.34 ENST00000442664.6
ENST00000409051.6
ENST00000410111.8
ENST00000620815.4
ENST00000449247.6
inner membrane mitochondrial protein
chr15_+_59105099 24.14 ENST00000288207.7
ENST00000559622.5
cyclin B2
chr15_-_41332487 23.98 ENST00000560640.1
ENST00000220514.8
Opa interacting protein 5
chr9_+_113275642 23.97 ENST00000374199.9
ENST00000374198.5
pre-mRNA processing factor 4
chr18_-_49492305 23.77 ENST00000615479.4
ENST00000583637.5
ENST00000618613.5
ENST00000615760.4
ENST00000578528.1
ENST00000578532.5
ENST00000580387.5
ENST00000579248.5
ENST00000580261.6
ENST00000581373.5
ENST00000618619.4
ENST00000617346.4
ENST00000583036.5
ENST00000332968.11
ribosomal protein L17
RPL17-C18orf32 readthrough
chr1_+_86704892 23.70 ENST00000482504.1
SH3 domain containing GRB2 like, endophilin B1
chr17_-_50397472 23.66 ENST00000576448.1
ENST00000225972.8
leucine rich repeat containing 59
chr1_-_74732997 23.53 ENST00000370872.7
ENST00000370871.7
ENST00000340866.10
ENST00000370870.5
crystallin zeta
chr2_+_113437691 23.50 ENST00000259199.9
ENST00000416503.6
ENST00000433343.6
COBW domain containing 2
chr1_-_6393750 23.50 ENST00000545482.5
ENST00000361521.9
acyl-CoA thioesterase 7
chr10_+_123154364 23.44 ENST00000368859.6
ENST00000368865.9
BUB3 mitotic checkpoint protein
chr8_-_54101855 23.39 ENST00000522007.5
ENST00000521898.5
ENST00000316963.8
ENST00000518546.5
lysophospholipase 1
chr9_-_41189310 23.34 ENST00000456520.5
ENST00000377391.8
ENST00000613716.4
ENST00000617933.1
COBW domain containing 6
chr20_-_34303345 23.30 ENST00000217426.7
adenosylhomocysteinase
chr3_-_63863791 23.30 ENST00000464327.2
ENST00000295899.10
ENST00000469584.5
THO complex 7
chr19_+_34365173 23.28 ENST00000589640.5
ENST00000591204.5
ENST00000589399.6
ENST00000356487.11
glucose-6-phosphate isomerase
chr8_-_47960126 23.16 ENST00000314191.7
ENST00000338368.7
protein kinase, DNA-activated, catalytic subunit
chr20_+_62302093 23.12 ENST00000491935.5
adhesion regulating molecule 1
chr7_+_157337520 23.12 ENST00000412557.5
ENST00000453383.5
DnaJ heat shock protein family (Hsp40) member B6
chr12_-_112418819 23.09 ENST00000551291.6
ribosomal protein L6
chr1_+_75724672 23.03 ENST00000370834.9
ENST00000370841.9
ENST00000679687.1
ENST00000420607.6
acyl-CoA dehydrogenase medium chain
chrX_+_119468436 22.93 ENST00000317881.9
solute carrier family 25 member 5
chr14_+_54397021 22.89 ENST00000541304.5
cyclin dependent kinase inhibitor 3
chr15_+_48331011 22.78 ENST00000559935.5
ENST00000559416.5
deoxyuridine triphosphatase
chr8_-_80030232 22.65 ENST00000518271.1
ENST00000276585.9
ENST00000521605.1
mitochondrial ribosomal protein S28
chr14_+_54396949 22.46 ENST00000611205.4
cyclin dependent kinase inhibitor 3
chr21_-_33588624 22.43 ENST00000437395.5
ENST00000453626.5
ENST00000303113.10
ENST00000303071.10
ENST00000432378.5
DNA replication fork stabilization factor DONSON
chr7_+_65373799 22.43 ENST00000357512.3
zinc finger protein 92
chr9_+_135499959 22.24 ENST00000371785.5
mitochondrial ribosomal protein S2
chr6_-_42048648 22.23 ENST00000502771.1
ENST00000508143.5
ENST00000514588.1
ENST00000510503.5
cyclin D3
chr2_-_42361198 22.22 ENST00000234301.3
cytochrome c oxidase subunit 7A2 like
chr13_-_21604145 22.16 ENST00000382374.9
ENST00000468222.2
mitochondrial calcium uptake 2
chr21_-_39183398 22.14 ENST00000331573.8
proteasome assembly chaperone 1
chr11_-_88337722 22.05 ENST00000677976.1
ENST00000528020.2
ENST00000393301.5
ENST00000529974.2
ENST00000227266.10
ENST00000678464.1
ENST00000679199.1
ENST00000527018.6
ENST00000679224.1
ENST00000678506.1
ENST00000678915.1
ENST00000524463.6
cathepsin C
chr8_+_26291494 21.98 ENST00000380737.8
ENST00000524169.5
protein phosphatase 2 regulatory subunit Balpha
chr7_-_16645728 21.85 ENST00000306999.7
ankyrin repeat and MYND domain containing 2
chr10_+_42782769 21.81 ENST00000374518.6
BMS1 ribosome biogenesis factor
chr2_+_201071984 21.79 ENST00000237889.9
ENST00000433898.5
ENST00000684175.1
ENST00000682325.1
ENST00000454214.1
ENST00000684420.1
NADH:ubiquinone oxidoreductase subunit B3
chr18_+_59899988 21.67 ENST00000316660.7
ENST00000269518.9
phorbol-12-myristate-13-acetate-induced protein 1
chr22_-_29553645 21.64 ENST00000397871.5
ENST00000397872.5
ENST00000440771.5
THO complex 5
chr17_-_75154503 21.45 ENST00000409753.8
ENST00000581874.1
Jupiter microtubule associated homolog 1
chr14_+_54396964 21.43 ENST00000543789.6
ENST00000442975.6
ENST00000458126.6
ENST00000556102.6
ENST00000335183.11
cyclin dependent kinase inhibitor 3
chr19_-_42302766 21.35 ENST00000595530.5
ENST00000538771.5
ENST00000601865.5
platelet activating factor acetylhydrolase 1b catalytic subunit 3
chr15_+_41332862 21.23 ENST00000450592.6
ENST00000414849.6
ENST00000559596.6
ENST00000560747.5
ENST00000560177.5
nucleolar and spindle associated protein 1
chr14_-_75069478 21.18 ENST00000555463.1
acylphosphatase 1
chr15_-_84716063 21.16 ENST00000558217.5
ENST00000558196.1
ENST00000558134.5
SEC11 homolog A, signal peptidase complex subunit
chr3_+_139344530 21.13 ENST00000478464.5
mitochondrial ribosomal protein S22
chr20_-_5126534 21.02 ENST00000379160.3
proliferating cell nuclear antigen
chr4_-_83109843 21.02 ENST00000411416.6
placenta associated 8
chr14_+_58244821 21.00 ENST00000216455.9
ENST00000412908.6
ENST00000557508.5
proteasome 20S subunit alpha 3
chr1_+_1013485 20.98 ENST00000649529.1
ISG15 ubiquitin like modifier
chr5_-_134226059 20.91 ENST00000519718.1
ENST00000481195.6
novel protein
protein phosphatase 2 catalytic subunit alpha
chr1_+_161749762 20.90 ENST00000367943.5
dual specificity phosphatase 12
chr6_+_30721573 20.87 ENST00000330914.7
tubulin beta class I
chr1_-_70205531 20.81 ENST00000370952.4
leucine rich repeat containing 40
chr1_+_155208727 20.71 ENST00000316721.8
metaxin 1
chr7_-_148883474 20.63 ENST00000476773.5
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr11_+_67606894 20.62 ENST00000532303.5
ENST00000532244.5
ENST00000528328.1
ENST00000322776.11
ENST00000529927.5
ENST00000532343.5
ENST00000415352.6
ENST00000533075.5
ENST00000529867.5
ENST00000530638.1
NADH:ubiquinone oxidoreductase core subunit V1
chr18_+_12308232 20.59 ENST00000590103.5
ENST00000591909.5
ENST00000586653.5
ENST00000317702.10
ENST00000592683.5
ENST00000590967.5
ENST00000591208.1
ENST00000591463.1
tubulin beta 6 class V
chr19_+_5690255 20.59 ENST00000582463.5
ENST00000347512.8
ENST00000579446.1
ENST00000394580.2
ribosomal protein L36
chr6_+_47477731 20.49 ENST00000359314.5
CD2 associated protein
chr12_-_123272234 20.47 ENST00000544658.5
cyclin dependent kinase 2 associated protein 1
chr20_-_33401501 20.36 ENST00000473997.5
ENST00000346416.7
ENST00000357886.8
ENST00000339269.5
CDK5 regulatory subunit associated protein 1
chr6_+_87590067 20.26 ENST00000546266.5
ENST00000257789.4
ENST00000392844.8
origin recognition complex subunit 3
chr12_-_119803383 20.24 ENST00000392520.2
ENST00000678677.1
ENST00000679249.1
ENST00000676849.1
citron rho-interacting serine/threonine kinase
chr10_+_68901258 20.19 ENST00000373585.8
DExD-box helicase 50
chr2_-_73737320 20.15 ENST00000272424.11
TP53RK binding protein
chr11_+_106077638 20.05 ENST00000278618.9
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr16_-_66934144 20.03 ENST00000568572.5
cytosolic iron-sulfur assembly component 2B
chr10_-_73247241 19.97 ENST00000372950.6
DnaJ heat shock protein family (Hsp40) member C9
chr1_-_53945661 19.96 ENST00000194214.10
heat shock protein family B (small) member 11
chr5_-_134632769 19.93 ENST00000505758.5
ENST00000439578.5
ENST00000502286.1
ENST00000402673.7
secretion associated Ras related GTPase 1B
chrX_+_154762813 19.88 ENST00000369550.10
ENST00000413910.5
dyskerin pseudouridine synthase 1
chr12_+_57230086 19.82 ENST00000414700.7
ENST00000557703.5
serine hydroxymethyltransferase 2
chr9_+_135500672 19.81 ENST00000241600.10
mitochondrial ribosomal protein S2
chr3_-_146544850 19.71 ENST00000472349.1
phospholipid scramblase 1
chr6_-_31806937 19.67 ENST00000375661.6
LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated
chr17_-_49707900 19.59 ENST00000511763.6
ENST00000515850.6
ENST00000649906.1
ENST00000240333.12
solute carrier family 35 member B1
chr9_+_68241854 19.55 ENST00000616550.4
ENST00000618217.4
ENST00000377342.9
ENST00000478048.5
ENST00000360171.11
COBW domain containing 3
chr11_-_62671540 19.54 ENST00000532208.5
ENST00000377954.3
ENST00000431002.6
ENST00000354588.7
ENST00000415855.6
LBH domain containing 1
chr1_+_7961653 19.53 ENST00000493678.5
ENST00000377493.9
ENST00000338639.10
Parkinsonism associated deglycase
chr5_+_10250216 19.41 ENST00000515390.5
chaperonin containing TCP1 subunit 5
chr15_+_66504959 19.39 ENST00000535141.6
ENST00000613446.4
ENST00000446801.6
zwilch kinetochore protein
chr2_-_84459232 19.30 ENST00000393868.7
succinate-CoA ligase GDP/ADP-forming subunit alpha
chr13_-_113208634 19.29 ENST00000375457.2
ENST00000375477.5
ENST00000337344.9
ENST00000246505.9
ENST00000622406.4
ENST00000375479.6
PCI domain containing 2
chr11_+_108665045 19.29 ENST00000322536.8
DEAD-box helicase 10
chr7_+_55887277 19.23 ENST00000426595.1
novel zinc finger protein 713 (ZNF713) and mitochondrial ribosomal protein S17 (MRPS17) protein
chr10_+_79347460 19.19 ENST00000225174.8
peptidylprolyl isomerase F
chr1_-_148152272 19.16 ENST00000682118.1
ENST00000615281.4
NBPF member 11
chr1_+_42658335 19.14 ENST00000677900.1
ENST00000372550.6
ENST00000676675.1
ENST00000304979.8
ENST00000678803.1
ENST00000678333.1
ENST00000440068.6
peptidylprolyl isomerase H
chr2_-_70302048 19.09 ENST00000430566.6
ENST00000037869.7
family with sequence similarity 136 member A
chr12_+_111842205 19.07 ENST00000550735.7
MAPK activated protein kinase 5
chr18_+_22933819 19.06 ENST00000399722.6
ENST00000399725.6
ENST00000399721.6
RB binding protein 8, endonuclease
chr1_+_1001002 19.02 ENST00000624697.4
ENST00000624652.1
ISG15 ubiquitin like modifier
chr9_+_65675834 18.98 ENST00000377392.9
ENST00000377384.5
ENST00000430059.6
ENST00000429800.6
ENST00000382405.8
ENST00000377395.8
COBW domain containing 5
chr7_-_26201301 18.93 ENST00000608362.2
ENST00000676749.1
ENST00000677839.1
heterogeneous nuclear ribonucleoprotein A2/B1
chr3_+_112990956 18.92 ENST00000383678.8
ENST00000383677.7
ENST00000619116.4
GTP binding protein 8 (putative)
chr15_+_59105205 18.91 ENST00000621385.1
cyclin B2
chr7_+_118184156 18.86 ENST00000422760.1
ENST00000249299.7
ENST00000411938.1
LSM8 homolog, U6 small nuclear RNA associated
chr2_+_215312028 18.80 ENST00000236959.14
ENST00000435675.5
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr1_+_161314372 18.80 ENST00000342751.8
ENST00000367975.7
ENST00000432287.6
ENST00000392169.6
ENST00000513009.5
succinate dehydrogenase complex subunit C
chr5_-_134004921 18.79 ENST00000265333.8
voltage dependent anion channel 1
chr10_+_58385395 18.72 ENST00000487519.6
ENST00000373895.7
transcription factor A, mitochondrial
chr12_+_104215772 18.66 ENST00000429002.6
ENST00000525566.6
thioredoxin reductase 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
31.5 94.5 GO:0046452 dihydrofolate metabolic process(GO:0046452)
23.1 69.2 GO:0046080 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
18.2 54.7 GO:0090669 telomerase RNA stabilization(GO:0090669)
16.9 101.4 GO:0009438 methylglyoxal metabolic process(GO:0009438)
16.1 48.3 GO:1904772 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
15.9 47.8 GO:0051793 medium-chain fatty acid catabolic process(GO:0051793)
15.7 47.0 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
15.0 59.8 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
14.0 153.9 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
13.4 53.4 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
13.0 13.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
12.6 37.7 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
12.5 100.1 GO:0090166 Golgi disassembly(GO:0090166)
12.5 37.5 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
12.3 49.2 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
12.3 36.8 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
11.8 11.8 GO:0043504 mitochondrial DNA repair(GO:0043504)
11.4 11.4 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
10.8 54.0 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
10.4 31.2 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
10.3 61.8 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
10.3 41.2 GO:2000653 regulation of genetic imprinting(GO:2000653)
10.2 20.5 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
10.0 30.0 GO:0072019 proximal convoluted tubule development(GO:0072019) metanephric proximal convoluted tubule development(GO:0072229)
9.8 78.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
9.3 9.3 GO:1903181 regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
9.2 27.7 GO:0014810 positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014810)
9.2 27.7 GO:1900195 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
9.2 36.9 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
9.2 46.0 GO:0044209 AMP salvage(GO:0044209)
9.1 27.4 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
8.7 43.3 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
8.4 25.1 GO:0007113 endomitotic cell cycle(GO:0007113)
8.4 25.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
8.3 50.0 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
8.2 16.4 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
7.9 31.8 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
7.7 30.9 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
7.6 30.5 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
7.6 22.8 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
7.5 59.7 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
7.4 29.5 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
7.3 43.9 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
7.3 36.3 GO:0009136 purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
7.1 21.4 GO:1905000 regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
7.1 14.2 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
7.0 20.9 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
6.9 13.9 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
6.8 20.3 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
6.7 39.9 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
6.6 19.9 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
6.6 52.8 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
6.6 39.5 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
6.5 45.7 GO:1904431 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) positive regulation of t-circle formation(GO:1904431)
6.5 19.6 GO:0072334 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
6.5 65.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
6.5 32.3 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
6.4 89.4 GO:0051096 positive regulation of helicase activity(GO:0051096)
6.4 31.8 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
6.4 19.1 GO:2000374 regulation of oxygen metabolic process(GO:2000374)
6.3 31.4 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
6.2 43.5 GO:1903333 negative regulation of protein folding(GO:1903333)
6.1 6.1 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
6.0 18.1 GO:1903352 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
6.0 66.2 GO:1902969 mitotic DNA replication(GO:1902969)
6.0 18.0 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
5.9 17.8 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
5.9 23.7 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
5.9 23.5 GO:0036114 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
5.7 17.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
5.7 40.1 GO:0090204 protein localization to nuclear pore(GO:0090204)
5.6 425.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
5.5 16.4 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
5.3 26.7 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
5.3 16.0 GO:0009085 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878)
5.3 26.7 GO:0051643 endoplasmic reticulum localization(GO:0051643)
5.3 26.4 GO:0043137 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
5.2 20.9 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
5.2 5.2 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
5.2 31.0 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
5.2 15.5 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
5.0 30.2 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
5.0 40.0 GO:0032020 ISG15-protein conjugation(GO:0032020)
5.0 15.0 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
4.9 14.7 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
4.9 29.1 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
4.8 67.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
4.8 19.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
4.8 19.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
4.7 28.3 GO:0006021 inositol biosynthetic process(GO:0006021)
4.7 75.1 GO:0043248 proteasome assembly(GO:0043248)
4.7 23.3 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
4.6 37.2 GO:0048478 replication fork protection(GO:0048478)
4.6 9.2 GO:0009838 abscission(GO:0009838)
4.6 23.0 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
4.6 13.7 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
4.5 131.6 GO:0006465 signal peptide processing(GO:0006465)
4.5 31.5 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
4.5 94.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
4.5 17.9 GO:0009440 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
4.4 31.0 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
4.4 52.3 GO:0001522 pseudouridine synthesis(GO:0001522)
4.3 13.0 GO:0006642 triglyceride mobilization(GO:0006642)
4.2 71.7 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
4.2 16.8 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
4.2 4.2 GO:0090235 regulation of metaphase plate congression(GO:0090235)
4.1 49.7 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
4.1 16.5 GO:0048254 snoRNA localization(GO:0048254)
4.1 12.3 GO:0009106 lipoate metabolic process(GO:0009106)
4.1 8.2 GO:1903978 regulation of microglial cell activation(GO:1903978)
4.1 32.7 GO:0042866 pyruvate biosynthetic process(GO:0042866)
4.1 52.7 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
4.0 12.1 GO:0006097 glyoxylate cycle(GO:0006097)
4.0 27.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
4.0 27.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
3.9 74.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
3.9 27.4 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
3.8 11.5 GO:1904732 regulation of electron carrier activity(GO:1904732)
3.8 15.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
3.7 22.5 GO:0015853 adenine transport(GO:0015853)
3.7 11.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
3.7 14.8 GO:1901873 regulation of post-translational protein modification(GO:1901873)
3.7 3.7 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
3.7 11.0 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
3.6 14.6 GO:1902775 mitochondrial ribosome assembly(GO:0061668) mitochondrial large ribosomal subunit assembly(GO:1902775)
3.6 36.4 GO:0060717 chorion development(GO:0060717)
3.6 50.7 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
3.6 14.4 GO:0016333 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
3.6 10.7 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
3.5 42.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
3.5 17.3 GO:0045900 negative regulation of translational elongation(GO:0045900)
3.4 17.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
3.4 13.7 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
3.4 23.9 GO:0032077 positive regulation of deoxyribonuclease activity(GO:0032077)
3.4 23.8 GO:0002326 B cell lineage commitment(GO:0002326)
3.3 13.4 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
3.2 13.0 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
3.2 12.9 GO:0003290 atrial septum secundum morphogenesis(GO:0003290)
3.2 134.2 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
3.2 9.6 GO:0090402 oncogene-induced cell senescence(GO:0090402)
3.2 15.9 GO:0090435 protein localization to nuclear envelope(GO:0090435)
3.2 34.8 GO:0042178 xenobiotic catabolic process(GO:0042178)
3.2 28.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
3.2 12.6 GO:1904045 cellular response to aldosterone(GO:1904045)
3.2 9.5 GO:0046967 cytosol to ER transport(GO:0046967)
3.1 9.4 GO:0043634 exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467) polyadenylation-dependent ncRNA catabolic process(GO:0043634) nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
3.1 59.0 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
3.1 46.2 GO:0070986 left/right axis specification(GO:0070986)
3.1 6.1 GO:0035511 oxidative DNA demethylation(GO:0035511)
3.1 30.7 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
3.1 15.4 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
3.1 9.2 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
3.1 15.3 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
3.0 36.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
3.0 15.1 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
3.0 39.0 GO:0045008 depyrimidination(GO:0045008)
2.9 11.7 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
2.9 23.0 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
2.9 8.6 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
2.9 2.9 GO:0021539 subthalamus development(GO:0021539)
2.8 8.4 GO:1990535 neuron projection maintenance(GO:1990535)
2.8 35.8 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
2.7 235.4 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
2.7 13.5 GO:0003164 His-Purkinje system development(GO:0003164)
2.7 5.4 GO:0031126 snoRNA 3'-end processing(GO:0031126)
2.7 37.4 GO:0030497 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
2.7 48.0 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
2.7 18.7 GO:0001887 selenium compound metabolic process(GO:0001887)
2.7 31.9 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
2.7 2.7 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
2.6 21.0 GO:1902031 regulation of NADP metabolic process(GO:1902031)
2.6 18.2 GO:0070200 establishment of protein localization to telomere(GO:0070200)
2.6 33.7 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
2.6 18.0 GO:0042998 regulation of Golgi to plasma membrane protein transport(GO:0042996) positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
2.6 10.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
2.6 5.1 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
2.5 30.5 GO:0006089 lactate metabolic process(GO:0006089)
2.5 52.9 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
2.5 7.6 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
2.5 170.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
2.5 10.0 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
2.5 7.4 GO:0033386 geranylgeranyl diphosphate metabolic process(GO:0033385) geranylgeranyl diphosphate biosynthetic process(GO:0033386)
2.4 19.5 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
2.4 9.7 GO:0030047 actin modification(GO:0030047)
2.4 7.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
2.4 16.9 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
2.4 40.9 GO:0051231 mitotic spindle elongation(GO:0000022) spindle elongation(GO:0051231)
2.4 114.3 GO:0007077 mitotic nuclear envelope disassembly(GO:0007077)
2.4 11.8 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
2.4 9.4 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
2.3 25.8 GO:0042276 error-prone translesion synthesis(GO:0042276)
2.3 23.5 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
2.3 16.3 GO:0000012 single strand break repair(GO:0000012)
2.3 30.2 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
2.3 11.6 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
2.3 6.9 GO:0002314 germinal center B cell differentiation(GO:0002314) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
2.3 16.0 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
2.3 25.0 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
2.3 22.6 GO:0040016 embryonic cleavage(GO:0040016)
2.3 20.3 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
2.3 20.3 GO:0001866 NK T cell proliferation(GO:0001866)
2.3 9.0 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
2.2 15.7 GO:1902188 positive regulation of viral release from host cell(GO:1902188)
2.2 11.2 GO:0006177 GMP biosynthetic process(GO:0006177)
2.2 11.0 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
2.2 15.3 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
2.2 6.6 GO:0006059 hexitol metabolic process(GO:0006059)
2.2 10.9 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
2.2 2.2 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
2.1 6.4 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
2.1 10.7 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
2.1 6.3 GO:0036233 glycine import(GO:0036233)
2.1 23.1 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
2.1 6.2 GO:0031456 glycine betaine biosynthetic process from choline(GO:0019285) glycine betaine metabolic process(GO:0031455) glycine betaine biosynthetic process(GO:0031456)
2.1 14.4 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
2.1 4.1 GO:0032687 negative regulation of interferon-alpha production(GO:0032687)
2.0 63.2 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
2.0 14.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
2.0 24.0 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
2.0 4.0 GO:0060003 copper ion export(GO:0060003)
2.0 9.9 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
2.0 5.9 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
2.0 3.9 GO:1903970 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
2.0 11.8 GO:1902570 protein localization to nucleolus(GO:1902570)
1.9 19.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
1.9 7.6 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
1.9 9.5 GO:0034351 regulation of glial cell apoptotic process(GO:0034350) negative regulation of glial cell apoptotic process(GO:0034351)
1.9 15.0 GO:0021943 formation of radial glial scaffolds(GO:0021943)
1.9 7.5 GO:0046952 ketone body catabolic process(GO:0046952)
1.8 5.5 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
1.8 60.7 GO:0007080 mitotic metaphase plate congression(GO:0007080)
1.8 9.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
1.8 23.7 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
1.8 9.1 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
1.8 12.7 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
1.8 116.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
1.8 63.9 GO:0034080 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.7 31.4 GO:0031639 plasminogen activation(GO:0031639)
1.7 8.7 GO:0006574 valine catabolic process(GO:0006574)
1.7 15.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
1.7 13.8 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
1.7 44.7 GO:0097340 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
1.7 8.4 GO:1901159 glucuronate catabolic process(GO:0006064) glucuronate catabolic process to xylulose 5-phosphate(GO:0019640) xylulose 5-phosphate metabolic process(GO:0051167) xylulose 5-phosphate biosynthetic process(GO:1901159)
1.7 5.0 GO:1902905 positive regulation of fibril organization(GO:1902905)
1.7 3.3 GO:0006404 RNA import into nucleus(GO:0006404)
1.7 13.2 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
1.6 136.1 GO:0045454 cell redox homeostasis(GO:0045454)
1.6 24.5 GO:0000338 protein deneddylation(GO:0000338)
1.6 6.5 GO:0003409 optic cup structural organization(GO:0003409)
1.6 9.7 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
1.6 6.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.6 19.1 GO:0090400 stress-induced premature senescence(GO:0090400)
1.6 7.8 GO:2000210 positive regulation of anoikis(GO:2000210)
1.6 3.1 GO:0090169 regulation of spindle assembly(GO:0090169)
1.5 6.2 GO:0048496 maintenance of organ identity(GO:0048496)
1.5 13.8 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
1.5 6.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
1.5 4.5 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
1.5 10.5 GO:1905123 regulation of glucosylceramidase activity(GO:1905123)
1.5 3.0 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
1.5 8.8 GO:0006591 ornithine metabolic process(GO:0006591)
1.5 60.9 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
1.4 8.6 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
1.4 7.1 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
1.4 14.3 GO:1903421 regulation of synaptic vesicle recycling(GO:1903421)
1.4 12.8 GO:0048069 eye pigmentation(GO:0048069)
1.4 5.7 GO:0032099 negative regulation of response to food(GO:0032096) negative regulation of appetite(GO:0032099)
1.4 18.4 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
1.4 49.2 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
1.4 16.8 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
1.4 8.4 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
1.4 8.4 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
1.4 8.3 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
1.4 5.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
1.4 2.7 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
1.3 6.7 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
1.3 34.6 GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435)
1.3 8.0 GO:0032506 cytokinetic process(GO:0032506)
1.3 5.2 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
1.3 9.1 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
1.3 11.7 GO:0042262 DNA protection(GO:0042262)
1.3 7.7 GO:0002934 desmosome organization(GO:0002934)
1.3 5.1 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
1.3 11.4 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
1.3 10.1 GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130)
1.3 21.4 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
1.2 86.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
1.2 2.5 GO:1903715 regulation of aerobic respiration(GO:1903715)
1.2 24.6 GO:0061157 mRNA destabilization(GO:0061157)
1.2 12.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
1.2 7.2 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
1.2 19.0 GO:0038003 opioid receptor signaling pathway(GO:0038003)
1.2 5.8 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
1.1 38.5 GO:0090307 mitotic spindle assembly(GO:0090307)
1.1 1.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
1.1 8.9 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
1.1 8.8 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
1.1 34.2 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
1.1 17.3 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
1.1 15.1 GO:0036158 outer dynein arm assembly(GO:0036158)
1.1 11.9 GO:0018206 peptidyl-methionine modification(GO:0018206)
1.1 41.9 GO:0000281 mitotic cytokinesis(GO:0000281)
1.1 29.9 GO:0002183 cytoplasmic translational initiation(GO:0002183)
1.0 6.3 GO:0006264 mitochondrial DNA replication(GO:0006264)
1.0 5.2 GO:0061738 late endosomal microautophagy(GO:0061738) negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
1.0 5.2 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
1.0 12.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
1.0 2.0 GO:0006550 isoleucine catabolic process(GO:0006550)
1.0 8.1 GO:0035524 proline transmembrane transport(GO:0035524)
1.0 3.0 GO:0019532 oxalate transport(GO:0019532) dipeptide transport(GO:0042938)
1.0 3.0 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
1.0 5.0 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
1.0 16.9 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
1.0 15.8 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
1.0 3.0 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
1.0 15.7 GO:0031167 rRNA methylation(GO:0031167)
1.0 5.9 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
1.0 6.8 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
1.0 8.6 GO:0046689 response to mercury ion(GO:0046689)
1.0 7.7 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
1.0 18.2 GO:0016578 histone deubiquitination(GO:0016578)
1.0 3.8 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.9 2.8 GO:0036510 trimming of terminal mannose on C branch(GO:0036510)
0.9 1.9 GO:1901355 response to rapamycin(GO:1901355)
0.9 13.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.9 2.7 GO:0019401 alditol biosynthetic process(GO:0019401)
0.9 3.6 GO:1904977 lymphatic endothelial cell migration(GO:1904977)
0.9 10.9 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.9 7.1 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.9 280.9 GO:0000375 RNA splicing, via transesterification reactions(GO:0000375)
0.9 12.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.9 22.0 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.9 11.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.9 38.7 GO:0045104 intermediate filament cytoskeleton organization(GO:0045104)
0.9 25.8 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.9 3.4 GO:0031179 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.8 3.3 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.8 33.6 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.8 2.4 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.8 2.4 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.8 3.2 GO:0035814 negative regulation of urine volume(GO:0035811) negative regulation of renal sodium excretion(GO:0035814)
0.8 4.8 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.8 16.0 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.8 24.5 GO:0006301 postreplication repair(GO:0006301)
0.8 3.9 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.8 35.3 GO:0051225 spindle assembly(GO:0051225)
0.8 3.9 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.8 3.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.8 4.5 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.8 1.5 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.7 3.7 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.7 6.6 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.7 4.4 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.7 10.2 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.7 8.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.7 7.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.7 15.7 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.7 12.7 GO:0030488 tRNA methylation(GO:0030488)
0.7 2.8 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.7 6.2 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.7 2.0 GO:0033499 galactose catabolic process via UDP-galactose(GO:0033499)
0.7 8.8 GO:0032310 prostaglandin secretion(GO:0032310)
0.7 18.0 GO:1903205 regulation of hydrogen peroxide-induced cell death(GO:1903205)
0.7 10.0 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.7 1.3 GO:0040031 snRNA modification(GO:0040031)
0.7 0.7 GO:1904432 antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) response to iron(III) ion(GO:0010041) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) cellular response to iron(III) ion(GO:0071283) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.7 17.8 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.7 2.6 GO:0044351 macropinocytosis(GO:0044351)
0.7 8.5 GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030949)
0.6 11.0 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.6 7.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.6 3.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.6 3.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.6 8.1 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.6 9.8 GO:0040032 parathyroid hormone secretion(GO:0035898) post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
0.6 1.8 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.6 6.7 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.6 6.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.6 68.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.6 1.8 GO:0097264 self proteolysis(GO:0097264)
0.6 4.2 GO:0071352 interleukin-2-mediated signaling pathway(GO:0038110) cellular response to interleukin-2(GO:0071352)
0.6 4.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.6 24.6 GO:0008033 tRNA processing(GO:0008033)
0.6 5.8 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.6 22.0 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.6 3.4 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.6 5.6 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.5 18.7 GO:0030318 melanocyte differentiation(GO:0030318)
0.5 7.6 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.5 30.7 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.5 2.6 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.5 17.8 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.5 24.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.5 5.5 GO:0007097 nuclear migration(GO:0007097)
0.5 4.0 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.5 57.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.5 3.4 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.5 12.6 GO:0010669 epithelial structure maintenance(GO:0010669)
0.5 11.6 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.5 12.5 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.5 15.8 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.5 6.0 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.5 29.7 GO:0006611 protein export from nucleus(GO:0006611)
0.4 5.8 GO:0015889 cobalamin transport(GO:0015889)
0.4 3.9 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.4 3.4 GO:0060413 atrial septum morphogenesis(GO:0060413)
0.4 10.1 GO:0006289 nucleotide-excision repair(GO:0006289)
0.4 6.3 GO:0016180 snRNA processing(GO:0016180)
0.4 2.4 GO:0006549 isoleucine metabolic process(GO:0006549)
0.4 2.0 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.4 6.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.4 9.1 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
0.4 2.0 GO:0048840 otolith development(GO:0048840)
0.4 0.4 GO:0032423 regulation of mismatch repair(GO:0032423) positive regulation of mismatch repair(GO:0032425)
0.4 12.0 GO:0006270 DNA replication initiation(GO:0006270)
0.4 0.8 GO:0046222 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.4 4.2 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.4 17.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.3 12.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.3 10.9 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.3 9.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 3.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3 3.7 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.3 2.0 GO:0061767 negative regulation of cardiac muscle adaptation(GO:0010616) positive regulation of transforming growth factor beta3 production(GO:0032916) negative regulation of lung blood pressure(GO:0061767) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.3 2.6 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.3 8.9 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.3 6.3 GO:0030252 growth hormone secretion(GO:0030252)
0.3 1.9 GO:0048875 chemical homeostasis within a tissue(GO:0048875)
0.3 26.5 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.3 8.1 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.3 2.1 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.3 6.0 GO:0050872 white fat cell differentiation(GO:0050872)
0.3 4.3 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.3 12.2 GO:0006364 rRNA processing(GO:0006364)
0.3 2.0 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.3 3.9 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.3 31.7 GO:0031424 keratinization(GO:0031424)
0.3 2.1 GO:0009597 detection of virus(GO:0009597)
0.3 3.6 GO:0006012 galactose metabolic process(GO:0006012)
0.3 0.5 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.3 3.6 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.3 2.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 5.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 16.8 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.2 3.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.2 0.7 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.2 4.2 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.2 1.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 1.6 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.2 4.4 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.2 19.6 GO:0034446 substrate adhesion-dependent cell spreading(GO:0034446)
0.2 0.6 GO:1904058 positive regulation of sensory perception of pain(GO:1904058)
0.2 13.6 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.2 3.3 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.2 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 2.1 GO:1902254 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.2 7.6 GO:0045333 cellular respiration(GO:0045333)
0.2 0.5 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.2 2.1 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.2 0.3 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.2 2.6 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.2 7.3 GO:0010595 positive regulation of endothelial cell migration(GO:0010595)
0.2 1.4 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 0.8 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.2 3.7 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.7 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 3.2 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 1.7 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.1 0.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 4.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.1 3.8 GO:0050766 positive regulation of phagocytosis(GO:0050766)
0.1 0.2 GO:0015917 aminophospholipid transport(GO:0015917)
0.1 1.0 GO:0038203 TORC2 signaling(GO:0038203)
0.1 0.7 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 1.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.1 9.7 GO:0048813 dendrite morphogenesis(GO:0048813)
0.1 1.0 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.1 3.8 GO:0090003 regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.1 0.2 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1 0.5 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 3.3 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.1 1.0 GO:0001967 suckling behavior(GO:0001967)
0.1 1.3 GO:0010842 retina layer formation(GO:0010842)
0.1 0.2 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 1.2 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 2.1 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 0.4 GO:0061205 nose morphogenesis(GO:0043585) alveolar primary septum development(GO:0061143) paramesonephric duct development(GO:0061205)
0.1 2.3 GO:0002260 lymphocyte homeostasis(GO:0002260)
0.1 0.3 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.1 1.6 GO:0006414 translational elongation(GO:0006414)
0.1 0.3 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 1.3 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 0.9 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.8 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.0 3.6 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.5 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:0071888 macrophage apoptotic process(GO:0071888)
0.0 0.2 GO:0006600 creatine metabolic process(GO:0006600)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
20.3 20.3 GO:0031261 nuclear pre-replicative complex(GO:0005656) DNA replication preinitiation complex(GO:0031261) pre-replicative complex(GO:0036387)
19.2 153.9 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
18.5 55.5 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
17.4 156.3 GO:0005787 signal peptidase complex(GO:0005787)
17.1 68.5 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
16.0 64.0 GO:0000811 GINS complex(GO:0000811)
15.0 59.8 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
14.6 43.9 GO:0071001 U4/U6 snRNP(GO:0071001)
13.1 91.4 GO:0090661 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
12.6 352.3 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
11.4 34.3 GO:0034515 proteasome storage granule(GO:0034515)
10.6 53.0 GO:0097149 centralspindlin complex(GO:0097149)
9.1 36.4 GO:1990423 RZZ complex(GO:1990423)
8.7 43.4 GO:0031523 Myb complex(GO:0031523)
7.8 93.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
7.8 38.8 GO:0045257 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
7.6 30.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
7.5 82.9 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
7.4 44.6 GO:0031298 replication fork protection complex(GO:0031298)
7.4 29.6 GO:0071942 XPC complex(GO:0071942)
7.1 28.4 GO:0071920 cleavage body(GO:0071920)
6.6 19.8 GO:0030689 Noc complex(GO:0030689)
6.4 32.0 GO:0000408 EKC/KEOPS complex(GO:0000408)
6.3 37.6 GO:0061617 MICOS complex(GO:0061617)
6.2 43.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
5.8 299.0 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
5.7 23.0 GO:0035363 histone locus body(GO:0035363)
5.7 28.3 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
5.5 71.7 GO:0005688 U6 snRNP(GO:0005688)
5.5 22.0 GO:0031510 SUMO activating enzyme complex(GO:0031510)
5.4 75.3 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
5.2 15.5 GO:0043159 acrosomal matrix(GO:0043159)
5.1 15.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
5.1 81.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
4.9 49.2 GO:0097255 R2TP complex(GO:0097255)
4.8 38.3 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
4.8 76.0 GO:0045120 pronucleus(GO:0045120)
4.7 66.3 GO:0070938 contractile ring(GO:0070938)
4.6 77.4 GO:0031080 nuclear pore outer ring(GO:0031080)
4.4 22.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
4.4 39.7 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
4.4 39.5 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
4.3 17.3 GO:1990246 uniplex complex(GO:1990246)
4.2 21.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
4.2 21.0 GO:0070557 PCNA-p21 complex(GO:0070557)
4.2 12.6 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942) Ndc80 complex(GO:0031262)
4.1 41.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
4.1 16.4 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
4.0 48.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
4.0 12.1 GO:0034677 integrin alpha7-beta1 complex(GO:0034677)
4.0 40.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
4.0 15.9 GO:0008537 proteasome activator complex(GO:0008537)
3.9 50.7 GO:0002199 zona pellucida receptor complex(GO:0002199)
3.6 28.6 GO:0031931 TORC1 complex(GO:0031931)
3.4 3.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
3.4 13.5 GO:0070876 SOSS complex(GO:0070876)
3.4 47.0 GO:0001741 XY body(GO:0001741)
3.3 20.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
3.3 16.4 GO:0001651 dense fibrillar component(GO:0001651) granular component(GO:0001652)
3.3 13.1 GO:0033186 CAF-1 complex(GO:0033186)
3.2 6.4 GO:1903349 omegasome membrane(GO:1903349)
3.1 27.9 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
3.1 9.3 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
3.1 196.9 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
3.1 33.8 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
3.1 15.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
3.0 307.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
2.9 14.4 GO:0042643 actomyosin, actin portion(GO:0042643)
2.9 14.3 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
2.9 59.9 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
2.8 16.5 GO:0070761 pre-snoRNP complex(GO:0070761)
2.7 13.7 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
2.7 58.8 GO:0035327 transcriptionally active chromatin(GO:0035327)
2.6 34.3 GO:0042555 MCM complex(GO:0042555)
2.6 21.1 GO:0000796 condensin complex(GO:0000796)
2.6 5.2 GO:0070939 Dsl1p complex(GO:0070939)
2.5 12.6 GO:0032301 MutSalpha complex(GO:0032301)
2.5 25.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
2.5 7.5 GO:0071821 FANCM-MHF complex(GO:0071821)
2.5 12.4 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
2.4 7.2 GO:0018444 translation release factor complex(GO:0018444)
2.3 16.3 GO:1990635 proximal dendrite(GO:1990635)
2.2 29.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
2.2 71.2 GO:0005640 nuclear outer membrane(GO:0005640)
2.2 19.8 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
2.2 32.9 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
2.2 6.6 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
2.2 6.6 GO:0097454 Schwann cell microvillus(GO:0097454)
2.2 19.6 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
2.1 14.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
2.1 22.7 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
2.1 14.4 GO:0044326 dendritic spine neck(GO:0044326)
2.0 6.1 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
2.0 14.2 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
2.0 14.2 GO:0016272 prefoldin complex(GO:0016272)
2.0 38.3 GO:0005641 nuclear envelope lumen(GO:0005641)
2.0 18.0 GO:1990630 IRE1-RACK1-PP2A complex(GO:1990630)
2.0 32.0 GO:0000178 exosome (RNase complex)(GO:0000178)
1.9 9.7 GO:0016589 NURF complex(GO:0016589)
1.9 7.7 GO:0036452 ESCRT complex(GO:0036452)
1.9 11.6 GO:0005839 proteasome core complex(GO:0005839)
1.9 45.7 GO:0016469 proton-transporting two-sector ATPase complex(GO:0016469)
1.9 9.5 GO:0042825 TAP complex(GO:0042825)
1.9 50.8 GO:0070469 respiratory chain(GO:0070469)
1.9 9.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
1.9 9.3 GO:0097422 tubular endosome(GO:0097422)
1.8 3.7 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
1.8 23.9 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
1.8 71.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
1.8 16.2 GO:0005828 kinetochore microtubule(GO:0005828)
1.8 57.1 GO:0030687 preribosome, large subunit precursor(GO:0030687)
1.8 17.8 GO:0051286 cell tip(GO:0051286)
1.7 12.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
1.7 38.4 GO:0030992 intraciliary transport particle B(GO:0030992)
1.7 5.2 GO:1902636 kinociliary basal body(GO:1902636)
1.7 33.8 GO:0030686 90S preribosome(GO:0030686)
1.7 16.9 GO:0032389 MutLalpha complex(GO:0032389)
1.7 65.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
1.7 30.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
1.6 28.8 GO:0032433 filopodium tip(GO:0032433)
1.6 14.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
1.6 17.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
1.6 15.5 GO:0010369 chromocenter(GO:0010369)
1.5 9.2 GO:0090543 Flemming body(GO:0090543)
1.5 10.6 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
1.5 12.0 GO:0070652 HAUS complex(GO:0070652)
1.5 25.2 GO:0005721 pericentric heterochromatin(GO:0005721)
1.5 7.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
1.5 17.5 GO:0033276 transcription factor TFTC complex(GO:0033276)
1.5 7.3 GO:0089701 U2AF(GO:0089701)
1.5 7.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
1.4 17.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
1.4 7.1 GO:0044327 dendritic spine head(GO:0044327)
1.4 48.2 GO:0000502 proteasome complex(GO:0000502)
1.4 28.3 GO:0005686 U2 snRNP(GO:0005686)
1.4 12.6 GO:0042382 paraspeckles(GO:0042382)
1.4 25.0 GO:0005720 nuclear heterochromatin(GO:0005720)
1.4 42.2 GO:0000421 autophagosome membrane(GO:0000421)
1.3 14.8 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
1.3 101.6 GO:0000777 condensed chromosome kinetochore(GO:0000777)
1.3 17.1 GO:0000815 ESCRT III complex(GO:0000815)
1.3 76.0 GO:0005876 spindle microtubule(GO:0005876)
1.3 10.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
1.3 37.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
1.3 6.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
1.3 2.6 GO:0000805 X chromosome(GO:0000805)
1.3 21.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
1.3 8.8 GO:0031088 platelet dense granule membrane(GO:0031088)
1.2 2.4 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
1.2 31.6 GO:0031264 death-inducing signaling complex(GO:0031264)
1.2 9.5 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
1.2 13.1 GO:0005845 mRNA cap binding complex(GO:0005845)
1.2 9.3 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
1.2 48.8 GO:0045095 keratin filament(GO:0045095)
1.2 8.1 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
1.1 12.0 GO:0044666 MLL3/4 complex(GO:0044666)
1.1 17.3 GO:0005662 DNA replication factor A complex(GO:0005662)
1.0 4.0 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
1.0 4.9 GO:0097504 Gemini of coiled bodies(GO:0097504)
1.0 4.9 GO:0035061 interchromatin granule(GO:0035061)
1.0 7.8 GO:0097526 U4/U6 x U5 tri-snRNP complex(GO:0046540) spliceosomal tri-snRNP complex(GO:0097526)
1.0 15.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.9 155.0 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.9 12.9 GO:0051233 spindle midzone(GO:0051233)
0.9 7.4 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.9 11.0 GO:0030008 TRAPP complex(GO:0030008)
0.9 9.0 GO:0061574 ASAP complex(GO:0061574)
0.9 9.9 GO:0000124 SAGA complex(GO:0000124)
0.9 4.4 GO:0032044 DSIF complex(GO:0032044)
0.9 30.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.9 11.4 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.9 12.2 GO:0070578 RISC-loading complex(GO:0070578)
0.9 10.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.9 14.6 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.8 2.4 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.8 0.8 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.8 17.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.8 8.7 GO:0070531 BRCA1-A complex(GO:0070531)
0.8 9.4 GO:0071203 WASH complex(GO:0071203)
0.8 16.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.7 35.6 GO:0015030 Cajal body(GO:0015030)
0.7 16.3 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.7 21.1 GO:0030057 desmosome(GO:0030057)
0.7 32.9 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.7 13.0 GO:0000776 kinetochore(GO:0000776)
0.7 10.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.7 6.7 GO:0005614 interstitial matrix(GO:0005614)
0.7 2.6 GO:0044307 dendritic branch(GO:0044307)
0.6 18.0 GO:0005844 polysome(GO:0005844)
0.6 46.2 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.6 6.3 GO:0032039 integrator complex(GO:0032039)
0.6 1.9 GO:0032426 stereocilium tip(GO:0032426)
0.6 20.1 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.6 1.8 GO:0035517 PR-DUB complex(GO:0035517)
0.6 32.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.6 11.8 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.6 3.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.6 88.1 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.6 9.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.5 4.9 GO:0000938 GARP complex(GO:0000938)
0.5 10.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.5 205.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.5 5.5 GO:0097433 dense body(GO:0097433)
0.5 7.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.5 17.8 GO:0008180 COP9 signalosome(GO:0008180)
0.5 4.5 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.4 3.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.4 15.6 GO:0031258 lamellipodium membrane(GO:0031258)
0.4 1.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.4 4.6 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.4 11.1 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.4 8.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.4 1.9 GO:0031673 H zone(GO:0031673)
0.4 5.5 GO:0032059 bleb(GO:0032059)
0.4 142.3 GO:0016607 nuclear speck(GO:0016607)
0.4 24.0 GO:0045178 basal part of cell(GO:0045178)
0.4 0.7 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.4 2.8 GO:0005642 annulate lamellae(GO:0005642)
0.3 20.1 GO:0043657 host(GO:0018995) host cell(GO:0043657)
0.3 56.3 GO:0031968 organelle outer membrane(GO:0031968)
0.3 9.1 GO:0031941 filamentous actin(GO:0031941)
0.3 5.0 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.3 8.4 GO:0000118 histone deacetylase complex(GO:0000118)
0.3 10.6 GO:0002102 podosome(GO:0002102)
0.3 2.2 GO:0005610 laminin-5 complex(GO:0005610)
0.3 22.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.3 19.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.3 3.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.3 6.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.3 7.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.2 248.8 GO:0005739 mitochondrion(GO:0005739)
0.2 2.9 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.2 3.5 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.2 2.0 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.2 18.1 GO:0016363 nuclear matrix(GO:0016363)
0.2 6.1 GO:0071564 SWI/SNF complex(GO:0016514) npBAF complex(GO:0071564)
0.2 8.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 20.9 GO:0030018 Z disc(GO:0030018)
0.2 1.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 34.6 GO:0042383 sarcolemma(GO:0042383)
0.2 13.4 GO:0005840 ribosome(GO:0005840)
0.2 1.0 GO:0000439 core TFIIH complex(GO:0000439)
0.2 6.0 GO:0001772 immunological synapse(GO:0001772)
0.2 5.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.7 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 17.4 GO:0005795 Golgi stack(GO:0005795)
0.1 1.0 GO:0031932 TORC2 complex(GO:0031932) TOR complex(GO:0038201)
0.1 26.0 GO:0000785 chromatin(GO:0000785)
0.1 16.6 GO:0034774 secretory granule lumen(GO:0034774)
0.1 5.3 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.0 1.5 GO:0030496 midbody(GO:0030496)
0.0 8.2 GO:0005730 nucleolus(GO:0005730)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
23.1 69.2 GO:0004170 dUTP diphosphatase activity(GO:0004170)
19.2 153.9 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
18.9 75.7 GO:0004146 dihydrofolate reductase activity(GO:0004146)
15.9 47.8 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
15.0 59.8 GO:0061656 SUMO conjugating enzyme activity(GO:0061656)
14.6 43.7 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
13.7 54.9 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
13.1 91.4 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
11.8 35.3 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
11.6 46.5 GO:0098770 FBXO family protein binding(GO:0098770)
10.7 10.7 GO:0004651 polynucleotide 5'-phosphatase activity(GO:0004651)
10.3 30.9 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
10.3 10.3 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
10.2 40.9 GO:0070404 NADH binding(GO:0070404)
9.9 29.6 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
9.8 49.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
9.8 39.1 GO:0031493 nucleosomal histone binding(GO:0031493)
9.6 57.4 GO:0044388 small protein activating enzyme binding(GO:0044388)
9.3 27.9 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
9.2 46.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
9.2 27.7 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
9.0 36.1 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
8.7 26.1 GO:0031403 lithium ion binding(GO:0031403)
8.4 25.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
8.3 33.3 GO:0047134 protein-disulfide reductase activity(GO:0047134)
8.2 32.7 GO:0004743 pyruvate kinase activity(GO:0004743)
7.9 31.8 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
7.9 31.8 GO:0002060 purine nucleobase binding(GO:0002060)
7.8 38.8 GO:0000104 succinate dehydrogenase activity(GO:0000104)
7.7 23.1 GO:0008670 2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
7.7 30.7 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
7.6 30.2 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
7.4 29.8 GO:0004001 adenosine kinase activity(GO:0004001)
7.1 28.4 GO:0033677 DNA/RNA helicase activity(GO:0033677)
7.0 21.0 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
6.5 32.7 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
6.5 19.6 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
6.3 63.5 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
6.3 19.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
6.1 24.6 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
6.1 24.5 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
6.0 18.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
6.0 168.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
6.0 18.0 GO:0010698 acetyltransferase activator activity(GO:0010698)
6.0 53.6 GO:0019784 NEDD8-specific protease activity(GO:0019784)
5.9 17.8 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
5.9 17.7 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
5.8 63.8 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
5.8 69.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
5.6 33.8 GO:0030620 U2 snRNA binding(GO:0030620)
5.6 61.8 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
5.6 22.5 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
5.6 73.0 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
5.6 39.0 GO:0061133 endopeptidase activator activity(GO:0061133)
5.5 27.7 GO:0050610 glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
5.2 52.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
5.2 15.6 GO:0001069 regulatory region RNA binding(GO:0001069)
5.1 36.0 GO:0004457 lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
5.1 5.1 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672)
5.0 24.8 GO:0008263 pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
4.9 29.1 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
4.8 19.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
4.8 53.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
4.8 19.3 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
4.8 86.8 GO:0017070 U6 snRNA binding(GO:0017070)
4.8 14.4 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
4.8 57.2 GO:0031386 protein tag(GO:0031386)
4.8 14.3 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
4.7 18.7 GO:0070363 mitochondrial light strand promoter sense binding(GO:0070363)
4.6 13.9 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
4.6 41.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
4.6 18.3 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
4.6 22.9 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
4.5 63.4 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
4.5 13.6 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
4.5 13.4 GO:0004566 beta-glucuronidase activity(GO:0004566)
4.5 13.4 GO:0004056 argininosuccinate lyase activity(GO:0004056)
4.4 26.5 GO:0034511 U3 snoRNA binding(GO:0034511)
4.4 26.4 GO:0019238 cyclohydrolase activity(GO:0019238)
4.4 39.5 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
4.4 21.8 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
4.3 43.0 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
4.3 21.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
4.2 8.4 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
4.2 12.6 GO:0009032 thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154)
4.1 12.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
4.0 12.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
4.0 71.7 GO:0035173 histone kinase activity(GO:0035173)
3.9 23.4 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
3.9 11.7 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
3.9 11.6 GO:0070704 C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
3.9 61.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
3.8 30.5 GO:0015288 porin activity(GO:0015288)
3.7 15.0 GO:0004074 biliverdin reductase activity(GO:0004074)
3.7 11.2 GO:0070259 tyrosyl-DNA phosphodiesterase activity(GO:0070259)
3.6 43.6 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
3.6 21.7 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
3.6 14.3 GO:0102345 3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
3.6 14.2 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
3.5 21.2 GO:0003998 acylphosphatase activity(GO:0003998)
3.3 13.3 GO:0001512 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
3.3 36.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
3.3 9.8 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
3.3 35.8 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
3.2 9.7 GO:0055100 adiponectin binding(GO:0055100)
3.2 6.4 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
3.2 22.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
3.1 55.8 GO:0016018 cyclosporin A binding(GO:0016018)
3.0 12.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
3.0 12.1 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
3.0 90.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
3.0 630.4 GO:0003735 structural constituent of ribosome(GO:0003735)
2.9 156.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
2.9 14.7 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
2.9 17.3 GO:0005047 signal recognition particle binding(GO:0005047)
2.9 8.7 GO:0003860 3-hydroxyisobutyryl-CoA hydrolase activity(GO:0003860)
2.9 11.4 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
2.8 14.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
2.8 16.8 GO:0036033 mediator complex binding(GO:0036033)
2.8 8.4 GO:1903135 cupric ion binding(GO:1903135)
2.8 22.1 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
2.7 35.5 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
2.7 8.2 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
2.7 13.6 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
2.7 29.7 GO:0005049 nuclear export signal receptor activity(GO:0005049)
2.6 70.5 GO:0048156 tau protein binding(GO:0048156)
2.6 23.5 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
2.6 15.6 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
2.6 28.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
2.5 12.6 GO:0032143 single thymine insertion binding(GO:0032143)
2.5 7.6 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
2.5 12.6 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
2.5 15.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
2.5 27.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
2.4 7.3 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
2.4 53.4 GO:0008242 omega peptidase activity(GO:0008242)
2.4 36.3 GO:0003688 DNA replication origin binding(GO:0003688)
2.4 50.3 GO:0070878 primary miRNA binding(GO:0070878)
2.4 12.0 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
2.3 30.5 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
2.3 9.4 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
2.3 28.0 GO:0097100 supercoiled DNA binding(GO:0097100)
2.3 23.3 GO:0070087 chromo shadow domain binding(GO:0070087)
2.3 14.0 GO:0015266 protein channel activity(GO:0015266)
2.3 11.5 GO:0016531 copper chaperone activity(GO:0016531)
2.2 22.2 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
2.2 6.7 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
2.2 26.6 GO:0019869 chloride channel inhibitor activity(GO:0019869)
2.1 27.7 GO:0031681 G-protein beta-subunit binding(GO:0031681)
2.1 52.9 GO:0034185 apolipoprotein binding(GO:0034185)
2.0 2.0 GO:0015616 DNA translocase activity(GO:0015616)
2.0 2.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
2.0 10.0 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
2.0 4.0 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
2.0 9.9 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
2.0 7.9 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
2.0 46.9 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
1.9 19.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
1.9 22.9 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
1.9 11.4 GO:0016748 succinyltransferase activity(GO:0016748)
1.9 58.8 GO:0000993 RNA polymerase II core binding(GO:0000993)
1.9 9.5 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
1.9 9.4 GO:1990254 keratin filament binding(GO:1990254)
1.9 5.6 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
1.9 14.8 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.8 5.5 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
1.8 25.8 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
1.8 12.9 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
1.8 21.9 GO:0031404 chloride ion binding(GO:0031404)
1.8 7.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
1.8 9.0 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
1.8 23.3 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
1.8 202.9 GO:0003697 single-stranded DNA binding(GO:0003697)
1.8 8.9 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
1.8 15.8 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
1.7 15.6 GO:1990226 histone methyltransferase binding(GO:1990226)
1.7 6.9 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
1.7 19.0 GO:0004985 opioid receptor activity(GO:0004985)
1.7 10.3 GO:0050815 phosphoserine binding(GO:0050815)
1.7 13.4 GO:0030911 TPR domain binding(GO:0030911)
1.7 14.9 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
1.6 3.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
1.6 13.1 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
1.6 57.5 GO:0001671 ATPase activator activity(GO:0001671)
1.6 62.0 GO:0005123 death receptor binding(GO:0005123)
1.6 9.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
1.6 17.1 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
1.5 15.5 GO:0001054 RNA polymerase I activity(GO:0001054)
1.5 107.8 GO:0003743 translation initiation factor activity(GO:0003743)
1.5 9.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
1.5 10.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
1.5 7.4 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
1.5 11.7 GO:0050733 RS domain binding(GO:0050733)
1.5 14.7 GO:0070569 uridylyltransferase activity(GO:0070569)
1.4 23.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
1.4 7.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
1.4 8.6 GO:0004532 exoribonuclease activity(GO:0004532)
1.4 39.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
1.4 7.0 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
1.4 8.4 GO:0004645 phosphorylase activity(GO:0004645)
1.4 29.5 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
1.4 18.2 GO:0016840 carbon-nitrogen lyase activity(GO:0016840)
1.4 19.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
1.4 12.3 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
1.4 24.5 GO:0070034 telomerase RNA binding(GO:0070034)
1.4 12.2 GO:0070883 pre-miRNA binding(GO:0070883)
1.3 12.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
1.3 12.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
1.3 10.7 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
1.3 4.0 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
1.3 6.6 GO:0071532 ankyrin repeat binding(GO:0071532)
1.3 34.2 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
1.3 34.9 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
1.3 29.5 GO:0070628 proteasome binding(GO:0070628)
1.3 33.0 GO:0032794 GTPase activating protein binding(GO:0032794)
1.3 21.5 GO:0016628 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
1.3 3.8 GO:0034046 poly(G) binding(GO:0034046)
1.3 37.7 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
1.2 8.7 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
1.2 3.6 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
1.2 7.3 GO:1990763 arrestin family protein binding(GO:1990763)
1.2 3.6 GO:0050501 hyaluronan synthase activity(GO:0050501)
1.2 7.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
1.2 9.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
1.2 2.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
1.1 14.8 GO:0051787 misfolded protein binding(GO:0051787)
1.1 20.5 GO:0070182 DNA polymerase binding(GO:0070182)
1.1 29.1 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
1.1 8.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
1.1 56.2 GO:0031491 nucleosome binding(GO:0031491)
1.1 4.4 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
1.1 7.6 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
1.1 38.7 GO:0008143 poly(A) binding(GO:0008143)
1.0 6.3 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
1.0 8.4 GO:0008097 5S rRNA binding(GO:0008097)
1.0 53.0 GO:0019894 kinesin binding(GO:0019894)
1.0 12.4 GO:0004526 ribonuclease P activity(GO:0004526)
1.0 11.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
1.0 8.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
1.0 8.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
1.0 7.0 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
1.0 10.0 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
1.0 18.9 GO:0003746 translation elongation factor activity(GO:0003746)
1.0 54.8 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
1.0 51.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
1.0 7.7 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
1.0 10.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
1.0 3.8 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
1.0 5.8 GO:0015235 cobalamin transporter activity(GO:0015235)
1.0 4.8 GO:0004771 sterol esterase activity(GO:0004771)
0.9 15.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.9 25.6 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.9 4.5 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.9 0.9 GO:0016419 [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420)
0.9 17.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.9 38.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.9 6.0 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.8 14.3 GO:0030515 snoRNA binding(GO:0030515)
0.8 4.2 GO:0008410 CoA-transferase activity(GO:0008410)
0.8 11.7 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.8 5.8 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.8 14.0 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.8 16.3 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.8 2.4 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.8 17.0 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.8 30.8 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.8 16.9 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.8 6.4 GO:0045545 syndecan binding(GO:0045545)
0.8 16.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.8 7.1 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.8 11.0 GO:0043495 protein anchor(GO:0043495)
0.8 17.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.8 48.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.8 9.9 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.8 79.1 GO:0051082 unfolded protein binding(GO:0051082)
0.7 3.0 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.7 18.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.7 3.7 GO:0043208 glycosphingolipid binding(GO:0043208)
0.7 4.3 GO:0004046 aminoacylase activity(GO:0004046)
0.7 7.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.7 7.7 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.7 4.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.7 12.7 GO:0097602 cullin family protein binding(GO:0097602)
0.7 35.3 GO:0003724 RNA helicase activity(GO:0003724)
0.7 11.8 GO:0097016 L27 domain binding(GO:0097016)
0.7 3.9 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.6 3.2 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.6 14.7 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.6 19.1 GO:0031748 D1 dopamine receptor binding(GO:0031748)
0.6 2.4 GO:0045569 TRAIL binding(GO:0045569)
0.6 26.3 GO:0050699 WW domain binding(GO:0050699)
0.6 1.7 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.6 9.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.6 3.4 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.6 4.6 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.6 3.4 GO:0035613 RNA stem-loop binding(GO:0035613)
0.6 26.8 GO:0031593 polyubiquitin binding(GO:0031593)
0.6 33.9 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.5 4.8 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.5 6.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.5 1.6 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.5 19.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.5 2.0 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.5 6.8 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.5 2.4 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.5 31.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.5 13.9 GO:0004385 guanylate kinase activity(GO:0004385)
0.5 5.7 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.5 2.8 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.5 9.9 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.5 8.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.5 3.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.5 4.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.4 2.7 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.4 6.9 GO:0004000 adenosine deaminase activity(GO:0004000)
0.4 5.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.4 7.1 GO:0051400 BH domain binding(GO:0051400)
0.4 6.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.4 26.4 GO:0043130 ubiquitin binding(GO:0043130)
0.4 2.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.4 2.0 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.4 3.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.4 10.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.4 5.2 GO:0000339 RNA cap binding(GO:0000339)
0.4 17.4 GO:0004407 histone deacetylase activity(GO:0004407)
0.4 4.3 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.4 5.8 GO:0016421 CoA carboxylase activity(GO:0016421)
0.4 4.7 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.4 3.1 GO:0030274 LIM domain binding(GO:0030274)
0.4 6.8 GO:0070410 co-SMAD binding(GO:0070410)
0.4 8.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.4 36.2 GO:0017048 Rho GTPase binding(GO:0017048)
0.4 2.8 GO:0034452 dynactin binding(GO:0034452)
0.3 58.0 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.3 12.7 GO:0032451 demethylase activity(GO:0032451)
0.3 14.6 GO:0061650 ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.3 112.0 GO:0045296 cadherin binding(GO:0045296)
0.3 0.7 GO:0070644 vitamin D response element binding(GO:0070644)
0.3 39.7 GO:0047485 protein N-terminus binding(GO:0047485)
0.3 3.9 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.3 3.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.3 8.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.3 13.5 GO:0016836 hydro-lyase activity(GO:0016836)
0.3 1.5 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.3 10.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.3 1.2 GO:0070513 death domain binding(GO:0070513)
0.3 13.2 GO:0009055 electron carrier activity(GO:0009055)
0.3 12.5 GO:0042169 SH2 domain binding(GO:0042169)
0.3 3.4 GO:0043295 glutathione binding(GO:0043295)
0.3 8.6 GO:0070566 adenylyltransferase activity(GO:0070566)
0.3 5.3 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.3 42.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.3 2.1 GO:0003678 DNA helicase activity(GO:0003678)
0.3 1.5 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 8.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 8.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.1 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.2 2.1 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 1.6 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.2 0.8 GO:0033897 ribonuclease T2 activity(GO:0033897)
0.2 0.8 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.2 4.3 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 5.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 10.9 GO:0004177 aminopeptidase activity(GO:0004177)
0.2 1.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 2.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 1.1 GO:0030228 low-density lipoprotein receptor activity(GO:0005041) lipoprotein particle receptor activity(GO:0030228)
0.1 3.8 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 0.5 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.1 3.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.6 GO:0017081 chloride channel regulator activity(GO:0017081)
0.1 5.9 GO:0032947 protein complex scaffold(GO:0032947)
0.1 1.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 87.0 GO:0003723 RNA binding(GO:0003723)
0.1 3.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 3.4 GO:0004950 G-protein coupled chemoattractant receptor activity(GO:0001637) chemokine receptor activity(GO:0004950)
0.1 0.6 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 1.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.1 1.7 GO:0042605 peptide antigen binding(GO:0042605)
0.1 0.3 GO:0005497 androgen binding(GO:0005497)
0.1 1.1 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0036505 prosaposin receptor activity(GO:0036505)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.8 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 1.3 GO:0003777 microtubule motor activity(GO:0003777)
0.0 1.1 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 1.0 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
7.1 99.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
3.5 81.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
3.4 99.0 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
3.1 9.2 PID CD40 PATHWAY CD40/CD40L signaling
2.6 102.8 PID ATM PATHWAY ATM pathway
2.4 346.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
2.1 135.3 PID PLK1 PATHWAY PLK1 signaling events
2.0 81.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
1.9 73.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
1.6 12.8 PID WNT SIGNALING PATHWAY Wnt signaling network
1.4 26.9 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
1.4 57.3 PID ATR PATHWAY ATR signaling pathway
1.3 23.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
1.2 108.5 PID E2F PATHWAY E2F transcription factor network
1.2 49.6 PID AURORA B PATHWAY Aurora B signaling
1.1 38.2 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
1.1 4.3 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
1.0 72.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.9 63.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.9 7.1 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.8 32.9 PID RHOA PATHWAY RhoA signaling pathway
0.8 8.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.7 30.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.7 47.3 PID TELOMERASE PATHWAY Regulation of Telomerase
0.7 24.2 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.7 58.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.7 8.5 PID IGF1 PATHWAY IGF1 pathway
0.6 17.3 PID IL3 PATHWAY IL3-mediated signaling events
0.6 16.4 PID TRAIL PATHWAY TRAIL signaling pathway
0.6 3.7 PID IL5 PATHWAY IL5-mediated signaling events
0.6 5.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.6 24.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.6 6.8 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.6 10.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.6 9.5 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.5 52.8 PID CMYB PATHWAY C-MYB transcription factor network
0.5 21.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.5 27.1 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.5 26.4 PID P53 REGULATION PATHWAY p53 pathway
0.5 6.6 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.5 23.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.5 24.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.5 2.9 ST G ALPHA I PATHWAY G alpha i Pathway
0.4 8.4 PID GLYPICAN 1PATHWAY Glypican 1 network
0.4 10.2 PID BARD1 PATHWAY BARD1 signaling events
0.4 16.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.3 16.2 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.3 18.0 PID P73PATHWAY p73 transcription factor network
0.3 6.8 PID IL6 7 PATHWAY IL6-mediated signaling events
0.3 11.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.3 2.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.3 0.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.2 7.8 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.2 10.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.2 4.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.2 6.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.2 13.0 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.2 2.7 PID ALK2 PATHWAY ALK2 signaling events
0.2 2.9 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 2.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 30.2 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.2 8.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.2 6.3 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.1 1.0 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 2.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 3.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 3.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 3.4 PID NOTCH PATHWAY Notch signaling pathway
0.1 3.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.9 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.4 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0 0.1 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
8.1 104.9 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
7.6 144.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
6.8 115.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
6.7 100.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
4.9 187.8 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
4.5 31.8 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
4.5 154.2 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
4.4 65.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
4.2 237.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
4.1 297.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
4.0 27.7 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
3.8 120.7 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
3.7 54.9 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
3.4 154.7 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
3.3 92.6 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
3.1 263.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
3.1 64.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
3.0 98.1 REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
3.0 50.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
3.0 26.6 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
2.9 48.5 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
2.8 14.0 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
2.6 85.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
2.6 30.8 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
2.4 67.7 REACTOME KINESINS Genes involved in Kinesins
2.4 57.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
2.4 44.7 REACTOME G2 M CHECKPOINTS Genes involved in G2/M Checkpoints
2.3 75.0 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
2.3 86.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
2.2 69.7 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
2.2 120.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
2.2 34.6 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
2.1 29.2 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
2.0 30.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
2.0 62.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
2.0 19.7 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
1.9 29.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
1.9 13.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
1.8 40.7 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
1.8 23.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
1.7 307.0 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
1.6 29.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
1.6 63.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
1.6 20.4 REACTOME P75NTR SIGNALS VIA NFKB Genes involved in p75NTR signals via NF-kB
1.5 43.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
1.4 24.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
1.4 17.2 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
1.4 167.0 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
1.3 38.7 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
1.3 34.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
1.2 86.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
1.1 63.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
1.1 11.1 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
1.0 36.3 REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
1.0 7.2 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
1.0 6.8 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.9 11.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.9 15.8 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.9 18.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.8 18.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.8 22.6 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.8 26.6 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.8 27.6 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.8 22.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.8 16.3 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.8 26.9 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.7 4.4 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.7 30.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.7 27.9 REACTOME CHROMOSOME MAINTENANCE Genes involved in Chromosome Maintenance
0.7 11.9 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.7 15.6 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.7 6.8 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.7 23.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.7 8.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.7 5.2 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.6 31.1 REACTOME TRANSLATION Genes involved in Translation
0.6 5.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.6 5.6 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.6 8.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.6 35.0 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.5 9.3 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.5 14.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.5 14.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.5 7.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.5 2.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.5 6.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.5 10.1 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.4 13.0 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.4 17.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.4 9.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.4 10.6 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.4 7.7 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.4 14.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.4 6.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.4 3.2 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.3 5.5 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.3 13.6 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.3 11.4 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.3 3.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.3 6.0 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 33.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.3 9.0 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3 5.7 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.3 5.2 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.2 5.0 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.2 6.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.2 7.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.2 6.9 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2 35.0 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.2 2.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 2.8 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.2 1.5 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.2 2.1 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 1.0 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.1 3.1 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 2.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 2.8 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.1 4.7 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 2.6 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.1 3.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 1.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 3.5 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.1 1.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 14.7 REACTOME METABOLISM OF CARBOHYDRATES Genes involved in Metabolism of carbohydrates
0.1 1.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.4 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.1 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.8 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 4.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1