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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for E2F4

Z-value: 6.53

Motif logo

Transcription factors associated with E2F4

Gene Symbol Gene ID Gene Info
ENSG00000205250.9 E2F4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F4hg38_v1_chr16_+_67192116_671922250.188.3e-03Click!

Activity profile of E2F4 motif

Sorted Z-values of E2F4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_10122315 39.63 ENST00000360566.6
ribonucleotide reductase regulatory subunit M2
chr2_+_10123171 30.47 ENST00000615152.5
ribonucleotide reductase regulatory subunit M2
chr7_-_100100716 21.01 ENST00000354230.7
ENST00000425308.5
minichromosome maintenance complex component 7
chr4_-_173333672 20.38 ENST00000438704.6
high mobility group box 2
chr1_-_197146620 19.30 ENST00000367409.9
ENST00000680265.1
assembly factor for spindle microtubules
chr1_-_197146688 19.15 ENST00000294732.11
assembly factor for spindle microtubules
chr2_+_171922442 19.09 ENST00000264108.5
histone acetyltransferase 1
chr7_-_100101333 17.28 ENST00000303887.10
minichromosome maintenance complex component 7
chr2_+_10122730 14.76 ENST00000304567.10
ribonucleotide reductase regulatory subunit M2
chr6_-_18264475 14.51 ENST00000515742.2
ENST00000651624.1
ENST00000507591.2
ENST00000652689.1
ENST00000244776.11
ENST00000503715.5
DEK proto-oncogene
chr17_-_78187036 14.39 ENST00000590862.5
ENST00000590430.5
ENST00000301634.12
ENST00000586613.1
thymidine kinase 1
chr6_-_52284677 13.79 ENST00000596288.7
ENST00000616552.4
ENST00000229854.12
ENST00000419835.8
minichromosome maintenance complex component 3
chr2_+_47403116 13.52 ENST00000645506.1
ENST00000406134.5
ENST00000233146.7
mutS homolog 2
chr2_+_47403061 12.99 ENST00000543555.6
mutS homolog 2
chr14_+_93207229 12.87 ENST00000554232.5
ENST00000556871.5
ENST00000013070.11
ENST00000555113.5
ubiquitin protein ligase E3 component n-recognin 7
chr10_-_73247241 12.76 ENST00000372950.6
DnaJ heat shock protein family (Hsp40) member C9
chr5_+_892844 11.85 ENST00000166345.8
thyroid hormone receptor interactor 13
chr4_-_1712310 11.75 ENST00000488267.5
ENST00000429429.6
ENST00000489418.6
ENST00000480936.1
stem-loop binding protein
chr17_+_40287861 11.62 ENST00000209728.9
ENST00000580824.5
ENST00000577249.1
ENST00000649662.1
cell division cycle 6
chr20_-_53593829 11.58 ENST00000371471.7
zinc finger protein 217
chr8_-_123396412 10.75 ENST00000287394.10
ATPase family AAA domain containing 2
chr6_+_135181268 10.61 ENST00000341911.10
ENST00000442647.7
ENST00000618728.4
ENST00000316528.12
ENST00000616088.4
MYB proto-oncogene, transcription factor
chr4_-_1712250 10.59 ENST00000318386.8
stem-loop binding protein
chr21_-_32279012 10.53 ENST00000290130.4
MIS18 kinetochore protein A
chr13_+_33818122 10.37 ENST00000380071.8
replication factor C subunit 3
chr3_+_179562886 10.35 ENST00000450518.6
ENST00000392662.5
ENST00000429709.7
ENST00000490364.1
actin like 6A
chr15_+_48332103 10.26 ENST00000455976.6
ENST00000559540.5
deoxyuridine triphosphatase
chr6_+_135181323 10.21 ENST00000367814.8
MYB proto-oncogene, transcription factor
chr8_+_127736046 10.15 ENST00000641036.1
ENST00000377970.6
MYC proto-oncogene, bHLH transcription factor
chr15_+_89243945 10.14 ENST00000674831.1
ENST00000300027.12
ENST00000567891.5
ENST00000310775.12
ENST00000676003.1
ENST00000564920.5
ENST00000565255.5
ENST00000567996.5
ENST00000563250.5
FA complementation group I
chr20_+_49046246 9.98 ENST00000396192.7
ENST00000262982.3
chromosome segregation 1 like
chr22_+_19479826 9.86 ENST00000437685.6
ENST00000263201.7
ENST00000404724.7
cell division cycle 45
chr22_+_24555981 9.82 ENST00000215829.8
ENST00000402849.5
small nuclear ribonucleoprotein D3 polypeptide
chr14_+_104753120 9.79 ENST00000535554.4
ENST00000329967.11
ENST00000347067.9
ENST00000553810.5
SIVA1 apoptosis inducing factor
chr8_+_127736220 9.72 ENST00000524013.2
ENST00000621592.8
MYC proto-oncogene, bHLH transcription factor
chr5_-_80654552 9.71 ENST00000511032.5
ENST00000504396.1
ENST00000505337.5
dihydrofolate reductase
chr8_+_47960883 9.55 ENST00000648407.1
ENST00000649838.1
ENST00000649919.1
ENST00000262105.6
ENST00000649973.1
minichromosome maintenance complex component 4
chr1_+_32651164 9.48 ENST00000373493.10
ENST00000373485.5
ENST00000458695.6
RB binding protein 4, chromatin remodeling factor
chr3_+_160399630 9.43 ENST00000465903.5
ENST00000485645.5
ENST00000472991.5
ENST00000467468.5
ENST00000469762.5
ENST00000357388.8
ENST00000489573.5
ENST00000462787.5
ENST00000490207.5
ENST00000485867.5
structural maintenance of chromosomes 4
chr12_-_102120065 9.34 ENST00000552283.6
ENST00000551744.2
nucleoporin 37
chr9_-_110256466 9.13 ENST00000374515.9
ENST00000374517.6
thioredoxin
chr1_+_32651142 9.09 ENST00000414241.7
RB binding protein 4, chromatin remodeling factor
chr11_+_59142728 8.74 ENST00000528737.5
FAM111 trypsin like peptidase A
chr9_+_107284053 8.54 ENST00000416373.6
RAD23 homolog B, nucleotide excision repair protein
chrX_-_119852948 8.34 ENST00000276201.7
ENST00000345865.6
UPF3B regulator of nonsense mediated mRNA decay
chr11_-_95923763 8.31 ENST00000497683.6
ENST00000470293.6
ENST00000674968.1
ENST00000484818.6
ENST00000675454.1
ENST00000675981.1
ENST00000674924.1
ENST00000676166.1
ENST00000676440.1
ENST00000675807.1
ENST00000495134.6
ENST00000675196.1
myotubularin related protein 2
chr2_+_47783172 8.24 ENST00000540021.6
mutS homolog 6
chr2_-_38751350 8.03 ENST00000409276.5
ENST00000313117.11
ENST00000446327.6
serine and arginine rich splicing factor 7
chr17_+_36544896 7.98 ENST00000611219.1
ENST00000613102.5
gametogenetin binding protein 2
chr11_+_59142811 7.81 ENST00000676459.1
ENST00000675163.1
ENST00000684135.1
ENST00000682018.1
ENST00000675806.2
ENST00000529985.3
ENST00000676340.1
ENST00000674617.1
FAM111 trypsin like peptidase A
chr7_-_103344588 7.66 ENST00000426036.6
ENST00000249270.11
ENST00000379263.8
ENST00000454277.5
ENST00000412522.1
DnaJ heat shock protein family (Hsp40) member C2
chr4_-_169757873 7.61 ENST00000393381.3
histone PARylation factor 1
chr8_+_42391895 7.54 ENST00000521158.5
voltage dependent anion channel 3
chrX_+_150983299 7.54 ENST00000325307.12
high mobility group box 3
chr1_-_8879170 7.47 ENST00000489867.2
enolase 1
chr7_-_158704740 7.07 ENST00000409339.3
ENST00000356309.8
ENST00000409423.5
non-SMC condensin II complex subunit G2
chr9_-_35079923 7.07 ENST00000378643.8
ENST00000448890.1
FA complementation group G
chr1_+_28518136 7.03 ENST00000373832.5
ENST00000373831.7
regulator of chromosome condensation 1
chr6_+_30720335 6.76 ENST00000327892.13
tubulin beta class I
chr19_-_1095261 6.74 ENST00000585838.2
ENST00000586746.5
ENST00000619917.4
ENST00000615234.5
ENST00000612655.4
RNA polymerase II, I and III subunit E
chr10_-_43396831 6.69 ENST00000443950.6
heterogeneous nuclear ribonucleoprotein F
chrX_+_134460138 6.53 ENST00000298556.8
hypoxanthine phosphoribosyltransferase 1
chr1_-_25859352 6.42 ENST00000374298.4
ENST00000538789.5
aurora kinase A and ninein interacting protein
chr3_+_180912656 6.33 ENST00000357559.9
ENST00000491062.5
ENST00000468861.5
ENST00000445140.6
ENST00000484958.5
FMR1 autosomal homolog 1
chr19_-_8005590 6.33 ENST00000407627.7
ENST00000593807.1
ELAV like RNA binding protein 1
chr7_-_74254362 6.32 ENST00000352131.7
ENST00000055077.8
ENST00000621097.4
replication factor C subunit 2
chr17_-_48101087 6.10 ENST00000393408.7
chromobox 1
chr10_+_90871946 6.04 ENST00000413330.5
ENST00000371703.8
ENST00000277882.7
ribonuclease P/MRP subunit p30
chr15_+_52019206 5.97 ENST00000681888.1
ENST00000261845.7
ENST00000680066.1
ENST00000680777.1
ENST00000680652.1
mitogen-activated protein kinase 6
chr19_-_6424802 5.92 ENST00000600480.2
KH-type splicing regulatory protein
chr8_+_42391840 5.84 ENST00000520115.5
ENST00000522069.5
ENST00000522572.5
ENST00000022615.9
voltage dependent anion channel 3
chr17_-_48101379 5.78 ENST00000581003.5
ENST00000225603.9
chromobox 1
chr1_+_63367619 5.75 ENST00000263440.6
ALG6 alpha-1,3-glucosyltransferase
chr8_+_47961028 5.68 ENST00000650216.1
minichromosome maintenance complex component 4
chr3_+_155870623 5.59 ENST00000295920.7
ENST00000496455.7
guanine monophosphate synthase
chr5_+_36151989 5.58 ENST00000274254.9
S-phase kinase associated protein 2
chr1_+_91501097 5.48 ENST00000428239.5
ENST00000426137.1
cell division cycle 7
chr1_+_91500827 5.47 ENST00000234626.11
cell division cycle 7
chr18_+_31498168 5.44 ENST00000261590.13
ENST00000585206.1
ENST00000683654.1
desmoglein 2
chr7_+_138460400 5.39 ENST00000415680.6
tripartite motif containing 24
chrX_+_150983350 5.38 ENST00000455596.5
ENST00000448905.6
high mobility group box 3
chr22_+_23966880 5.36 ENST00000215770.6
D-dopachrome tautomerase like
chr2_+_71130586 5.33 ENST00000498451.2
ENST00000244230.7
M-phase phosphoprotein 10
chr22_-_17774412 5.27 ENST00000342111.9
ENST00000622694.5
BH3 interacting domain death agonist
chr7_+_138460238 5.23 ENST00000343526.9
tripartite motif containing 24
chr16_+_88803776 5.18 ENST00000301019.9
chromatin licensing and DNA replication factor 1
chr12_+_49323236 5.16 ENST00000549275.5
ENST00000551245.5
ENST00000380327.9
ENST00000548311.5
ENST00000257909.8
ENST00000550346.5
ENST00000550709.5
ENST00000549534.1
ENST00000547807.5
ENST00000551567.1
trophinin associated protein
chr1_-_53945661 5.11 ENST00000194214.10
heat shock protein family B (small) member 11
chr2_+_27217361 5.06 ENST00000264705.9
ENST00000403525.5
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr10_-_17617235 5.06 ENST00000466335.1
3-hydroxyacyl-CoA dehydratase 1
chr12_+_2959296 5.03 ENST00000358409.7
ENST00000359864.8
ENST00000540314.2
ENST00000536826.2
TEA domain transcription factor 4
chr1_-_37989978 4.93 ENST00000373019.5
splicing factor 3a subunit 3
chr1_+_26921715 4.87 ENST00000321265.10
nuclear distribution C, dynein complex regulator
chr7_-_30504744 4.87 ENST00000409390.5
ENST00000409144.5
ENST00000409436.2
ENST00000275428.9
ENST00000005374.10
gamma-glutamylcyclotransferase
chr17_+_68205453 4.84 ENST00000674770.2
archaelysin family metallopeptidase 2
chr12_-_57078739 4.82 ENST00000379391.7
nuclear envelope integral membrane protein 1
chr10_-_86521737 4.73 ENST00000298767.10
WAPL cohesin release factor
chr3_-_100401028 4.71 ENST00000284320.6
translocase of outer mitochondrial membrane 70
chr8_-_17246846 4.68 ENST00000628418.1
ENST00000361272.9
ENST00000523917.5
CCR4-NOT transcription complex subunit 7
chr12_-_57078784 4.64 ENST00000300128.9
nuclear envelope integral membrane protein 1
chr1_+_28518266 4.63 ENST00000411533.5
regulator of chromosome condensation 1
chr14_+_63852951 4.63 ENST00000357395.7
ENST00000358025.7
ENST00000344113.8
ENST00000341472.9
ENST00000555002.6
spectrin repeat containing nuclear envelope protein 2
chr19_-_48170323 4.58 ENST00000263274.12
ENST00000427526.6
DNA ligase 1
chr17_-_40647809 4.53 ENST00000580419.6
ENST00000348513.12
ENST00000643806.1
ENST00000478349.7
ENST00000264640.9
ENST00000644527.1
ENST00000645104.1
ENST00000577721.6
ENST00000580654.6
ENST00000644701.1
ENST00000646283.1
ENST00000431889.6
ENST00000377808.9
ENST00000447024.6
ENST00000642459.1
ENST00000474246.2
ENST00000647515.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr18_+_50375037 4.53 ENST00000398452.6
ENST00000417656.6
ENST00000488454.5
ENST00000285116.8
ENST00000494518.1
spindle and kinetochore associated complex subunit 1
chr3_+_37861849 4.50 ENST00000273179.10
CTD small phosphatase like
chr2_+_188292814 4.47 ENST00000409580.5
ENST00000409637.7
GULP PTB domain containing engulfment adaptor 1
chr7_-_96709855 4.46 ENST00000444799.5
ENST00000417009.5
ENST00000248566.3
SEM1 26S proteasome complex subunit
chr4_+_177309866 4.46 ENST00000264596.4
nei like DNA glycosylase 3
chr1_+_53946323 4.45 ENST00000371370.8
ENST00000319223.8
ENST00000444987.1
leucine rich repeat containing 42
chr3_+_37861926 4.45 ENST00000443503.6
CTD small phosphatase like
chr11_-_95924067 4.44 ENST00000676027.1
ENST00000675489.1
ENST00000409459.5
ENST00000676261.1
ENST00000352297.11
ENST00000346299.10
ENST00000676272.1
ENST00000393223.8
ENST00000675022.1
ENST00000675362.1
ENST00000675174.1
ENST00000674989.1
ENST00000675848.1
ENST00000675652.1
ENST00000481642.6
myotubularin related protein 2
chr15_-_50355150 4.29 ENST00000220429.12
ENST00000429662.6
GA binding protein transcription factor subunit beta 1
chr6_-_27146841 4.25 ENST00000356950.2
H2B clustered histone 12
chr16_-_8868994 4.22 ENST00000311052.10
ENST00000565287.5
ENST00000611932.4
calcium regulated heat stable protein 1
chr15_+_90717321 4.14 ENST00000355112.8
ENST00000681142.1
ENST00000648453.1
ENST00000560509.5
BLM RecQ like helicase
chr11_-_119101814 4.03 ENST00000682791.1
ENST00000639704.1
ENST00000354202.9
dolichyl-phosphate N-acetylglucosaminephosphotransferase 1
chr3_-_48609625 4.00 ENST00000203407.6
ubiquinol-cytochrome c reductase core protein 1
chr8_-_94895195 3.99 ENST00000308108.9
ENST00000396133.7
cyclin E2
chr15_-_50355173 3.96 ENST00000558970.2
ENST00000380877.8
ENST00000396464.7
ENST00000560825.5
GA binding protein transcription factor subunit beta 1
chr5_-_43557024 3.95 ENST00000306846.8
ENST00000514514.5
ENST00000504075.1
ENST00000436644.6
poly(A) binding protein interacting protein 1
chr2_+_68157877 3.95 ENST00000263657.7
partner of NOB1 homolog
chr3_-_185938006 3.88 ENST00000342294.4
ENST00000453386.7
ENST00000382191.4
transformer 2 beta homolog
chr19_+_2236816 3.87 ENST00000221494.10
splicing factor 3a subunit 2
chr10_-_119080794 3.85 ENST00000369144.8
ENST00000541549.2
eukaryotic translation initiation factor 3 subunit A
chr19_-_47113756 3.84 ENST00000253048.10
zinc finger CCCH-type containing 4
chr6_+_160991727 3.78 ENST00000366919.6
ENST00000392142.9
ENST00000366920.6
ENST00000348824.11
mitogen-activated protein kinase kinase kinase 4
chr12_+_102120172 3.75 ENST00000327680.7
ENST00000541394.5
ENST00000543784.5
PARP1 binding protein
chr1_+_95234184 3.72 ENST00000370202.5
ENST00000263893.10
RWD domain containing 3
chr19_+_19405655 3.70 ENST00000683918.1
GATA zinc finger domain containing 2A
chr16_-_1773113 3.68 ENST00000397375.7
ENST00000177742.7
mitochondrial ribosomal protein S34
chrX_-_15493234 3.65 ENST00000380420.10
pirin
chr6_-_159789660 3.61 ENST00000538128.5
ENST00000537390.5
ENST00000392168.6
t-complex 1
chr7_+_77798832 3.60 ENST00000415251.6
ENST00000275575.11
putative homeodomain transcription factor 2
chr5_+_36152077 3.58 ENST00000546211.6
ENST00000620197.5
ENST00000678270.1
ENST00000679015.1
ENST00000678580.1
ENST00000274255.11
ENST00000508514.5
S-phase kinase associated protein 2
chr20_+_23350755 3.57 ENST00000254998.3
nuclear transport factor 2 like export factor 1
chr4_-_39366342 3.56 ENST00000503784.1
ENST00000349703.7
ENST00000381897.5
replication factor C subunit 1
chr14_-_70600643 3.56 ENST00000554963.5
ENST00000256379.10
ENST00000430055.6
ENST00000440435.2
ENST00000615788.4
mediator complex subunit 6
chr2_+_188292771 3.43 ENST00000359135.7
GULP PTB domain containing engulfment adaptor 1
chr15_+_40695423 3.40 ENST00000526763.6
ENST00000532743.6
RAD51 recombinase
chr2_+_27051637 3.37 ENST00000451003.5
ENST00000360131.5
ENST00000323064.12
ATP/GTP binding protein like 5
chr15_-_55993599 3.36 ENST00000435532.8
NEDD4 E3 ubiquitin protein ligase
chr2_-_128028114 3.29 ENST00000259234.10
Sin3A associated protein 130
chr2_-_27409523 3.28 ENST00000344034.5
protein phosphatase, Mg2+/Mn2+ dependent 1G
chr19_-_17245889 3.27 ENST00000291442.4
nuclear receptor subfamily 2 group F member 6
chr11_-_78574759 3.24 ENST00000281038.10
ENST00000529571.1
asparaginyl-tRNA synthetase 2, mitochondrial
chr17_-_13017952 3.22 ENST00000578071.1
ENST00000426905.7
ENST00000395962.6
ENST00000338034.9
ENST00000583371.5
elaC ribonuclease Z 2
chr22_-_17774482 3.21 ENST00000399765.5
ENST00000614949.4
ENST00000399767.6
BH3 interacting domain death agonist
chr1_+_10430384 3.16 ENST00000470413.6
ENST00000602787.6
ENST00000309048.8
CENPS-CORT readthrough
centromere protein S
chr17_-_58514617 3.05 ENST00000682306.1
myotubularin related protein 4
chr2_-_128028010 3.03 ENST00000643581.2
ENST00000450957.1
Sin3A associated protein 130
chr4_+_112637120 3.01 ENST00000509061.5
ENST00000344442.10
ENST00000508577.5
ENST00000513553.5
La ribonucleoprotein 7, transcriptional regulator
chr21_+_34073569 3.00 ENST00000399312.3
ENST00000381151.5
ENST00000362077.4
mitochondrial ribosomal protein S6
solute carrier family 5 member 3
novel transcript
chr14_+_88562952 3.00 ENST00000302216.12
ENST00000554602.5
ENST00000556945.5
ENST00000556158.5
ENST00000557607.5
ENST00000555799.5
ENST00000251038.10
ENST00000555755.5
zinc finger CCCH-type containing 14
chr7_+_77798750 2.99 ENST00000416283.6
ENST00000422959.6
ENST00000307305.12
ENST00000424760.5
putative homeodomain transcription factor 2
chr11_+_86244745 2.95 ENST00000528180.5
ENST00000263360.11
ENST00000672825.1
embryonic ectoderm development
chr8_-_144517785 2.93 ENST00000617875.6
ENST00000621189.4
RecQ like helicase 4
chr15_+_51829644 2.92 ENST00000308580.12
tropomodulin 3
chr2_+_177212724 2.91 ENST00000677043.1
ENST00000677863.1
ENST00000676681.1
ENST00000678111.1
ENST00000676874.1
ENST00000676736.1
ENST00000411529.6
ENST00000435711.5
heterogeneous nuclear ribonucleoprotein A3
chr19_+_50384323 2.91 ENST00000599857.7
ENST00000613923.6
ENST00000601098.6
ENST00000440232.7
ENST00000595904.6
ENST00000593887.1
DNA polymerase delta 1, catalytic subunit
chrX_+_71533095 2.91 ENST00000373719.8
ENST00000373701.7
O-linked N-acetylglucosamine (GlcNAc) transferase
chr18_+_11981015 2.85 ENST00000589238.5
inositol monophosphatase 2
chr17_-_17281232 2.85 ENST00000417352.5
ENST00000268717.10
COP9 signalosome subunit 3
chr14_+_102592611 2.83 ENST00000262241.7
REST corepressor 1
chr5_+_141969074 2.80 ENST00000506938.5
ENST00000394520.7
ENST00000394514.6
ENST00000512565.5
ring finger protein 14
chr16_-_67660694 2.80 ENST00000219251.13
ENST00000620338.4
ACD shelterin complex subunit and telomerase recruitment factor
chr8_+_94719865 2.80 ENST00000414645.6
dpy-19 like 4
chr22_+_41092585 2.80 ENST00000263253.9
E1A binding protein p300
chr11_-_119095456 2.78 ENST00000530167.1
H2A.X variant histone
chr17_-_43125450 2.76 ENST00000494123.5
ENST00000468300.5
ENST00000471181.7
ENST00000652672.1
BRCA1 DNA repair associated
chr20_-_33686371 2.76 ENST00000343380.6
E2F transcription factor 1
chr17_-_43125353 2.74 ENST00000476777.5
ENST00000491747.6
ENST00000478531.5
ENST00000357654.9
ENST00000477152.5
ENST00000618469.1
ENST00000352993.7
ENST00000493795.5
ENST00000493919.5
BRCA1 DNA repair associated
chr1_-_36149450 2.72 ENST00000373163.5
trafficking protein particle complex 3
chr5_+_139293728 2.71 ENST00000510056.5
ENST00000511249.5
ENST00000394805.8
ENST00000503811.5
ENST00000618441.5
matrin 3
chr11_+_17276708 2.70 ENST00000531172.5
ENST00000529010.6
ENST00000533738.6
ENST00000323688.10
nucleobindin 2
chr19_+_12938598 2.69 ENST00000586760.2
ENST00000316448.10
ENST00000588454.6
calreticulin
chr5_+_139293700 2.64 ENST00000504045.5
ENST00000504311.5
ENST00000502499.5
matrin 3
chr5_-_43313403 2.63 ENST00000325110.11
3-hydroxy-3-methylglutaryl-CoA synthase 1
chr1_+_15409858 2.61 ENST00000375980.9
EF-hand domain family member D2
chr16_-_8868687 2.60 ENST00000618335.4
ENST00000570125.5
calcium regulated heat stable protein 1
chr5_-_43313473 2.59 ENST00000433297.2
3-hydroxy-3-methylglutaryl-CoA synthase 1
chr12_+_15911324 2.58 ENST00000524480.5
ENST00000428559.7
ENST00000531803.5
ENST00000532964.5
deoxyribose-phosphate aldolase
chr11_+_68030896 2.57 ENST00000525628.1
NADH:ubiquinone oxidoreductase core subunit S8
chr10_-_68471911 2.56 ENST00000358410.8
ENST00000399180.3
DNA replication helicase/nuclease 2
chr9_-_109498251 2.53 ENST00000374541.4
ENST00000262539.7
protein tyrosine phosphatase non-receptor type 3
chr7_+_131110087 2.49 ENST00000421797.6
muskelin 1
chr17_-_43125300 2.46 ENST00000497488.1
ENST00000354071.7
ENST00000489037.1
ENST00000470026.5
ENST00000644555.1
ENST00000586385.5
ENST00000591534.5
ENST00000591849.5
BRCA1 DNA repair associated
chr11_+_34051722 2.46 ENST00000341394.9
ENST00000389645.7
cell cycle associated protein 1
chr21_-_43076362 2.45 ENST00000359624.7
ENST00000352178.9
cystathionine beta-synthase
chr7_-_42932148 2.44 ENST00000223321.9
ENST00000445517.1
ENST00000677581.1
proteasome 20S subunit alpha 2
novel PSMA2 and C7orf25 readthrough
chr1_+_229626170 2.43 ENST00000258243.7
URB2 ribosome biogenesis homolog
chr6_+_135181361 2.41 ENST00000527615.5
ENST00000420123.6
ENST00000525369.5
ENST00000528774.5
ENST00000533624.5
ENST00000534044.5
ENST00000534121.5
MYB proto-oncogene, transcription factor
chr8_+_123072667 2.38 ENST00000519418.5
ENST00000287380.6
ENST00000327098.9
ENST00000522420.5
ENST00000521676.5
TBC1 domain family member 31
chr18_-_56651122 2.38 ENST00000590954.5
thioredoxin like 1
chr19_-_10502745 2.36 ENST00000393623.6
kelch like ECH associated protein 1
chr10_-_68471882 2.31 ENST00000551118.6
DNA replication helicase/nuclease 2
chrX_-_20141810 2.29 ENST00000379593.1
ENST00000379607.10
eukaryotic translation initiation factor 1A X-linked
chr6_-_27831557 2.28 ENST00000611927.2
H4 clustered histone 12
chr11_+_110429898 2.27 ENST00000260270.3
ferredoxin 1
chr5_+_141968886 2.22 ENST00000347642.7
ring finger protein 14

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
12.8 38.4 GO:0009786 regulation of asymmetric cell division(GO:0009786)
8.8 26.5 GO:0010520 meiotic gene conversion(GO:0006311) regulation of reciprocal meiotic recombination(GO:0010520)
7.7 23.2 GO:1990922 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
5.0 19.9 GO:0090096 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
4.4 57.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
4.2 37.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
3.8 95.1 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
3.7 22.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
3.3 16.7 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
3.3 9.9 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
3.2 9.7 GO:0046452 dihydrofolate metabolic process(GO:0046452)
2.9 11.6 GO:1904117 traversing start control point of mitotic cell cycle(GO:0007089) response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
2.8 8.3 GO:0006166 purine ribonucleoside salvage(GO:0006166)
2.7 8.0 GO:0070510 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
2.5 7.6 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
2.4 4.9 GO:0043504 mitochondrial DNA repair(GO:0043504)
2.2 13.4 GO:0015853 adenine transport(GO:0015853)
1.8 11.0 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
1.7 5.2 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163) regulation of DNA replication origin binding(GO:1902595)
1.7 20.4 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
1.7 5.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
1.6 4.8 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
1.6 4.7 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) regulation of chromosome condensation(GO:0060623) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
1.6 9.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.5 9.2 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
1.5 10.6 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
1.3 9.1 GO:0006662 glycerol ether metabolic process(GO:0006662)
1.3 3.8 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
1.3 16.4 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
1.3 8.8 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
1.2 10.8 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
1.2 12.8 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
1.1 4.6 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
1.1 3.4 GO:0051821 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) development involved in symbiotic interaction(GO:0044111) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
1.1 5.6 GO:0006177 GMP biosynthetic process(GO:0006177)
1.1 11.8 GO:0007144 female meiosis I(GO:0007144)
1.1 3.2 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
1.0 3.0 GO:0015798 myo-inositol transport(GO:0015798)
0.9 3.8 GO:0007538 primary sex determination(GO:0007538)
0.9 8.5 GO:0000710 meiotic mismatch repair(GO:0000710)
0.9 2.8 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.9 4.6 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.9 5.4 GO:0003164 His-Purkinje system development(GO:0003164)
0.9 4.4 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.8 4.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806) cellular response to camptothecin(GO:0072757)
0.8 4.0 GO:0019348 dolichol metabolic process(GO:0019348)
0.8 7.2 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
0.8 7.7 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.7 2.8 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.7 7.5 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.7 2.7 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
0.7 8.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.6 2.6 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.6 10.4 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.6 7.3 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.6 1.8 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.6 19.1 GO:0006270 DNA replication initiation(GO:0006270)
0.6 4.0 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.6 1.7 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.6 2.8 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.6 1.7 GO:0003099 positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.5 4.7 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.5 2.1 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.5 10.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.5 6.0 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.5 9.8 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.5 2.4 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.5 2.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.5 2.9 GO:0006021 inositol biosynthetic process(GO:0006021)
0.5 11.7 GO:0051290 protein heterotetramerization(GO:0051290)
0.5 3.7 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.4 3.0 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.4 1.3 GO:0031990 regulation of chromatin assembly(GO:0010847) mRNA export from nucleus in response to heat stress(GO:0031990) positive regulation of chromatin assembly or disassembly(GO:0045799)
0.4 3.6 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.4 5.2 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.4 1.6 GO:0010266 response to vitamin B1(GO:0010266)
0.4 8.0 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.4 1.9 GO:0007386 compartment pattern specification(GO:0007386)
0.4 6.8 GO:0044030 regulation of DNA methylation(GO:0044030)
0.4 3.3 GO:0035608 protein deglutamylation(GO:0035608)
0.4 9.9 GO:0043968 histone H2A acetylation(GO:0043968)
0.3 2.4 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.3 2.0 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.3 2.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.3 3.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.3 1.3 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.3 1.3 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
0.3 4.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.3 6.3 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.3 3.9 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.3 24.1 GO:0032392 DNA geometric change(GO:0032392)
0.3 1.2 GO:0072711 cellular response to hydroxyurea(GO:0072711)
0.3 1.7 GO:0030538 embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619)
0.3 2.5 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
0.3 1.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.3 4.7 GO:0042761 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.3 2.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.3 4.9 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.3 1.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.3 1.6 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.3 8.4 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.3 6.3 GO:2000637 positive regulation of posttranscriptional gene silencing(GO:0060148) positive regulation of gene silencing by miRNA(GO:2000637)
0.3 22.1 GO:0032781 positive regulation of ATPase activity(GO:0032781)
0.3 2.8 GO:0070933 histone H4 deacetylation(GO:0070933)
0.3 3.0 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.3 9.3 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.2 1.0 GO:0072133 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.2 0.7 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2 2.1 GO:0000012 single strand break repair(GO:0000012)
0.2 1.6 GO:0040031 snRNA modification(GO:0040031)
0.2 3.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 2.8 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.2 2.3 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.2 1.8 GO:0089700 protein kinase D signaling(GO:0089700)
0.2 1.0 GO:0008063 Toll signaling pathway(GO:0008063)
0.2 0.4 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
0.2 0.6 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2 18.5 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.2 3.0 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.2 2.7 GO:0043248 proteasome assembly(GO:0043248)
0.2 2.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.2 4.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.2 0.6 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 1.3 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 1.9 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.1 0.7 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 1.8 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 4.1 GO:0009649 entrainment of circadian clock(GO:0009649)
0.1 1.0 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1 1.7 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 5.0 GO:0035329 hippo signaling(GO:0035329)
0.1 5.7 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 4.0 GO:0048255 mRNA stabilization(GO:0048255)
0.1 0.5 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 0.8 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 1.6 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 2.1 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.1 1.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.7 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 6.7 GO:0001541 ovarian follicle development(GO:0001541)
0.1 8.4 GO:0060999 positive regulation of dendritic spine development(GO:0060999)
0.1 1.7 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 12.3 GO:0043488 regulation of mRNA stability(GO:0043488)
0.1 1.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 5.3 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.1 6.2 GO:0006611 protein export from nucleus(GO:0006611)
0.1 1.9 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 7.4 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.1 3.6 GO:0030224 monocyte differentiation(GO:0030224)
0.1 2.0 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 4.7 GO:0071806 protein transmembrane transport(GO:0071806)
0.1 1.0 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.1 4.2 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.1 0.6 GO:1902414 protein localization to cell junction(GO:1902414)
0.1 2.9 GO:0051028 mRNA transport(GO:0051028)
0.1 0.7 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.1 0.6 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 4.0 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.1 3.9 GO:0045454 cell redox homeostasis(GO:0045454)
0.1 1.2 GO:0036344 platelet morphogenesis(GO:0036344)
0.0 3.7 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 5.3 GO:0051225 spindle assembly(GO:0051225)
0.0 1.7 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.0 1.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 1.6 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.8 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 3.2 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.0 0.8 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 2.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.4 GO:0021800 cerebral cortex tangential migration(GO:0021800) interneuron migration from the subpallium to the cortex(GO:0021830) cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.3 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 2.6 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.9 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.9 GO:1903077 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 1.2 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.0 4.6 GO:0046718 viral entry into host cell(GO:0046718)
0.0 0.9 GO:0006284 base-excision repair(GO:0006284)
0.0 0.1 GO:0070650 endoplasmic reticulum polarization(GO:0061163) actin filament bundle retrograde transport(GO:0061573) actin filament bundle distribution(GO:0070650)
0.0 0.2 GO:0070459 prolactin secretion(GO:0070459)
0.0 2.2 GO:0070268 cornification(GO:0070268)
0.0 0.6 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.0 0.9 GO:0001510 RNA methylation(GO:0001510)
0.0 0.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 1.6 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 3.6 GO:0042254 ribosome biogenesis(GO:0042254)
0.0 0.3 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.3 GO:0019372 lipoxygenase pathway(GO:0019372)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
21.2 84.9 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
7.0 35.0 GO:0032301 MutSalpha complex(GO:0032301)
4.8 62.8 GO:0042555 MCM complex(GO:0042555)
4.6 18.6 GO:0033186 CAF-1 complex(GO:0033186)
3.8 34.6 GO:0036449 microtubule minus-end(GO:0036449)
3.3 9.9 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
2.9 20.3 GO:0005663 DNA replication factor C complex(GO:0005663)
2.3 13.7 GO:0001940 male pronucleus(GO:0001940)
2.1 8.5 GO:0071942 XPC complex(GO:0071942)
2.1 10.6 GO:0005726 perichromatin fibrils(GO:0005726)
2.1 16.5 GO:0000796 condensin complex(GO:0000796)
2.0 22.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
2.0 9.8 GO:0005683 U7 snRNP(GO:0005683)
1.6 8.0 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
1.5 4.5 GO:0005760 gamma DNA polymerase complex(GO:0005760)
1.3 4.0 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
1.3 5.3 GO:0034457 Mpp10 complex(GO:0034457)
1.1 3.2 GO:0071821 FANCM-MHF complex(GO:0071821)
1.0 6.0 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.9 4.7 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.9 7.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.9 2.8 GO:0035189 Rb-E2F complex(GO:0035189)
0.8 11.8 GO:0001673 male germ cell nucleus(GO:0001673)
0.7 2.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.7 2.6 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.6 1.9 GO:1903349 omegasome membrane(GO:1903349)
0.6 4.8 GO:0070187 telosome(GO:0070187)
0.6 4.7 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.6 2.9 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.6 1.7 GO:0044611 nuclear pore inner ring(GO:0044611)
0.5 9.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.5 10.4 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.5 11.6 GO:0046930 pore complex(GO:0046930)
0.5 5.8 GO:0000800 lateral element(GO:0000800)
0.5 4.7 GO:0008278 cohesin complex(GO:0008278)
0.5 6.8 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.5 6.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.4 2.7 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.4 6.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.4 4.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.4 1.6 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.4 3.8 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.4 11.8 GO:0051233 spindle midzone(GO:0051233)
0.4 4.3 GO:0030008 TRAPP complex(GO:0030008)
0.4 4.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.3 7.5 GO:0070822 Sin3-type complex(GO:0070822)
0.3 1.3 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.3 9.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.3 4.0 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.3 2.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.3 4.0 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.3 45.9 GO:0016363 nuclear matrix(GO:0016363)
0.3 7.3 GO:0000178 exosome (RNase complex)(GO:0000178)
0.3 2.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.3 0.8 GO:0098536 deuterosome(GO:0098536)
0.2 2.7 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2 3.9 GO:0005686 U2 snRNP(GO:0005686)
0.2 1.9 GO:0072546 ER membrane protein complex(GO:0072546)
0.2 16.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.2 3.9 GO:0005662 DNA replication factor A complex(GO:0005662)
0.2 5.1 GO:0030992 intraciliary transport particle B(GO:0030992)
0.2 1.6 GO:0034709 methylosome(GO:0034709)
0.2 13.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.2 5.4 GO:0030057 desmosome(GO:0030057)
0.2 17.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.2 1.3 GO:0042575 DNA polymerase complex(GO:0042575)
0.2 1.5 GO:0001739 sex chromatin(GO:0001739)
0.2 9.0 GO:0045171 intercellular bridge(GO:0045171)
0.2 8.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 8.4 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.1 16.0 GO:0000793 condensed chromosome(GO:0000793)
0.1 4.5 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 8.5 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.1 1.9 GO:0030056 hemidesmosome(GO:0030056)
0.1 6.3 GO:0043034 costamere(GO:0043034)
0.1 3.0 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 1.5 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 14.5 GO:0031901 early endosome membrane(GO:0031901)
0.1 3.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 8.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 0.4 GO:0070847 core mediator complex(GO:0070847)
0.1 2.9 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 2.4 GO:0016235 aggresome(GO:0016235)
0.1 1.8 GO:0034399 nuclear periphery(GO:0034399)
0.1 2.7 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 2.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 6.4 GO:0000922 spindle pole(GO:0000922)
0.0 2.1 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 2.5 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.6 GO:0072686 mitotic spindle(GO:0072686)
0.0 2.4 GO:0000502 proteasome complex(GO:0000502)
0.0 1.9 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 2.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 2.8 GO:0016605 PML body(GO:0016605)
0.0 2.4 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.0 1.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.0 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.0 GO:0002102 podosome(GO:0002102)
0.0 1.6 GO:0005643 nuclear pore(GO:0005643)
0.0 2.4 GO:0005884 actin filament(GO:0005884)
0.0 5.3 GO:0043292 contractile fiber(GO:0043292)
0.0 8.0 GO:0005694 chromosome(GO:0005694)
0.0 4.7 GO:0005635 nuclear envelope(GO:0005635)
0.0 4.6 GO:0019866 organelle inner membrane(GO:0019866)
0.0 0.7 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
21.2 84.9 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
8.0 32.2 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
7.0 35.0 GO:0032143 single thymine insertion binding(GO:0032143)
5.1 20.4 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
3.4 10.3 GO:0004170 dUTP diphosphatase activity(GO:0004170)
2.9 20.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
2.4 9.7 GO:0004146 dihydrofolate reductase activity(GO:0004146)
2.1 23.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
1.9 11.5 GO:0047134 protein-disulfide reductase activity(GO:0047134)
1.7 5.2 GO:0004421 hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
1.7 5.1 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
1.7 13.4 GO:0015288 porin activity(GO:0015288)
1.5 7.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
1.5 8.8 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
1.5 11.7 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
1.3 11.9 GO:1990226 histone methyltransferase binding(GO:1990226)
1.3 5.1 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
1.2 53.5 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
1.2 16.9 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
1.2 10.6 GO:0034056 estrogen response element binding(GO:0034056)
1.1 4.5 GO:0000405 bubble DNA binding(GO:0000405)
1.0 7.2 GO:0004797 thymidine kinase activity(GO:0004797)
1.0 4.0 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
1.0 22.6 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.9 7.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.9 4.4 GO:0004122 cystathionine beta-synthase activity(GO:0004122)
0.8 33.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.7 15.8 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.7 2.1 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
0.7 2.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.7 5.4 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.6 11.0 GO:0000400 four-way junction DNA binding(GO:0000400)
0.6 10.9 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.6 4.6 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.6 5.0 GO:0033592 RNA strand annealing activity(GO:0033592)
0.5 9.3 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.5 5.6 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.5 3.0 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.5 4.0 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.5 2.9 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.5 3.4 GO:0050815 phosphoserine binding(GO:0050815)
0.5 2.8 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.4 4.9 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.4 1.3 GO:0003896 DNA primase activity(GO:0003896)
0.4 6.7 GO:0001054 RNA polymerase I activity(GO:0001054)
0.4 6.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.4 2.0 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.4 2.0 GO:0016882 cyclo-ligase activity(GO:0016882)
0.4 1.9 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.4 2.7 GO:0001849 complement component C1q binding(GO:0001849)
0.4 6.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.4 5.8 GO:0046527 glucosyltransferase activity(GO:0046527)
0.4 2.9 GO:0052834 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.4 29.9 GO:0003684 damaged DNA binding(GO:0003684)
0.3 9.8 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.3 1.3 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.3 19.9 GO:0070888 E-box binding(GO:0070888)
0.3 4.7 GO:0022884 protein transmembrane transporter activity(GO:0008320) macromolecule transmembrane transporter activity(GO:0022884)
0.3 5.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.3 1.7 GO:0031708 endothelin B receptor binding(GO:0031708)
0.3 1.6 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.3 6.8 GO:0032794 GTPase activating protein binding(GO:0032794)
0.2 0.7 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.2 1.7 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.2 0.7 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.2 1.6 GO:0005497 androgen binding(GO:0005497)
0.2 0.7 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.2 8.5 GO:0005123 death receptor binding(GO:0005123)
0.2 1.7 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.2 8.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.2 1.5 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.2 6.0 GO:0004707 MAP kinase activity(GO:0004707)
0.2 3.3 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.2 6.7 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 1.7 GO:0030274 LIM domain binding(GO:0030274)
0.2 1.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 4.0 GO:0008494 translation activator activity(GO:0008494)
0.2 1.6 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.2 1.8 GO:0004645 phosphorylase activity(GO:0004645)
0.2 32.3 GO:0042393 histone binding(GO:0042393)
0.2 1.9 GO:0038132 neuregulin binding(GO:0038132)
0.2 5.1 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.1 0.7 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.6 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.1 1.8 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.9 GO:0099602 acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.1 3.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 2.8 GO:0000030 mannosyltransferase activity(GO:0000030)
0.1 3.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 2.9 GO:0005523 tropomyosin binding(GO:0005523)
0.1 3.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 12.2 GO:0004386 helicase activity(GO:0004386)
0.1 1.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 4.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 6.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 12.8 GO:0031072 heat shock protein binding(GO:0031072)
0.1 4.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.1 2.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.6 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 1.8 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.8 GO:0097602 cullin family protein binding(GO:0097602)
0.1 1.0 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.1 2.1 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 11.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.2 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.1 19.0 GO:0005516 calmodulin binding(GO:0005516)
0.1 0.9 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.3 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.1 0.6 GO:0032183 SUMO binding(GO:0032183)
0.1 0.5 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 4.9 GO:0051082 unfolded protein binding(GO:0051082)
0.1 4.0 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.1 2.1 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 0.7 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 2.7 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.0 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 2.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.9 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 1.1 GO:0070717 poly-purine tract binding(GO:0070717)
0.0 1.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.9 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 4.1 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 2.2 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.0 2.3 GO:0009055 electron carrier activity(GO:0009055)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 7.4 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 0.5 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 1.6 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 2.8 GO:0003735 structural constituent of ribosome(GO:0003735)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 185.3 PID E2F PATHWAY E2F transcription factor network
0.9 49.9 PID ATR PATHWAY ATR signaling pathway
0.5 19.5 PID MYC PATHWAY C-MYC pathway
0.5 12.6 PID ATM PATHWAY ATM pathway
0.4 26.7 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.2 1.7 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.2 17.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.2 3.6 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2 7.6 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.2 23.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 6.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.2 9.4 PID AURORA B PATHWAY Aurora B signaling
0.2 4.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.2 26.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 6.5 PID PLK1 PATHWAY PLK1 signaling events
0.1 3.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 12.7 PID CMYB PATHWAY C-MYB transcription factor network
0.1 5.8 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.6 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 1.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 0.7 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 1.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 8.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 5.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.0 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 1.0 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.9 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.7 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.7 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 1.9 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 1.0 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.6 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.7 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 77.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
3.6 106.9 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
2.1 32.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
1.6 20.9 REACTOME POL SWITCHING Genes involved in Polymerase switching
1.5 13.3 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
1.5 22.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
1.2 27.9 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.0 29.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.9 14.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.7 11.0 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.6 12.5 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.6 4.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.5 9.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.5 7.6 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.4 29.6 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.4 8.5 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.4 38.1 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.3 8.5 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.3 6.7 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.3 10.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.3 7.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.3 6.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.3 5.4 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 7.0 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.2 3.9 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.2 1.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.2 2.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 6.3 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.2 28.1 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.2 19.3 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.2 5.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 5.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.2 4.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 4.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 8.5 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.1 5.2 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 4.0 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.6 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 4.7 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1 2.1 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.1 1.7 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 6.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 6.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 4.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 0.9 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.1 5.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 1.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 1.2 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.1 0.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 2.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.8 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 0.8 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 3.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 2.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases