ISMARA results: E2F6

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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for E2F6

Z-value: 0.37

Motif logo

Transcription factors associated with E2F6

Gene Symbol	Gene ID	Gene Info
E2F6 Ensembl NCBI GeneCards UniProt	ENSG00000169016.17	E2F6

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
E2F6	hg38_v1_chr2_-_11466156_11466177	0.16	1.9e-02	Click!

Activity profile of E2F6 motif

Sorted Z-values of E2F6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F6

View svg image
View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr7_+_116525028 Show fit	19.16	ENST00000341049.7	CAV1 Ensembl NCBI GeneCards UniProt Show fit	caveolin 1
chr1_-_67833448 Show fit	16.22	ENST00000370982.4	GNG12 Ensembl NCBI GeneCards UniProt Show fit	G protein subunit gamma 12
chr12_-_15882261 Show fit	13.48	ENST00000646918.1 ENST00000647087.1 ENST00000535752.5	EPS8 Ensembl NCBI GeneCards UniProt Show fit	epidermal growth factor receptor pathway substrate 8
chr7_+_94394886 Show fit	12.80	ENST00000297268.11 ENST00000620463.1	COL1A2 Ensembl NCBI GeneCards UniProt Show fit	collagen type I alpha 2 chain
chr7_+_116524984 Show fit	12.76	ENST00000614113.5 ENST00000393470.1	CAV1 Ensembl NCBI GeneCards UniProt Show fit	caveolin 1
chr12_+_6200327 Show fit	12.65	ENST00000610354.5	CD9 Ensembl NCBI GeneCards UniProt Show fit	CD9 molecule
chr13_+_110307276 Show fit	12.61	ENST00000360467.7 ENST00000650540.1	COL4A2 Ensembl NCBI GeneCards UniProt Show fit	collagen type IV alpha 2 chain
chr12_+_6200759 Show fit	12.21	ENST00000645565.1 ENST00000382515.7	CD9 Ensembl NCBI GeneCards UniProt Show fit	CD9 molecule
chrX_+_115561162 Show fit	11.98	ENST00000355899.8 ENST00000626746.2 ENST00000289290.7	PLS3 Ensembl NCBI GeneCards UniProt Show fit	plastin 3
chr2_-_215436061 Show fit	11.45	ENST00000421182.5 ENST00000432072.6 ENST00000323926.10 ENST00000336916.8 ENST00000357867.8 ENST00000359671.5 ENST00000446046.5 ENST00000354785.11 ENST00000356005.8 ENST00000443816.5 ENST00000426059.1	FN1 Ensembl NCBI GeneCards UniProt Show fit	fibronectin 1
chr11_+_46381194 Show fit	11.21	ENST00000533952.5	MDK Ensembl NCBI GeneCards UniProt Show fit	midkine
chr11_+_46381645 Show fit	11.18	ENST00000617138.4 ENST00000395566.9 ENST00000395569.8	MDK Ensembl NCBI GeneCards UniProt Show fit	midkine
chrX_-_129523436 Show fit	10.64	ENST00000371123.5 ENST00000371121.5 ENST00000371122.8	SMARCA1 Ensembl NCBI GeneCards UniProt Show fit	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr10_-_125161019 Show fit	9.95	ENST00000411419.6	CTBP2 Ensembl NCBI GeneCards UniProt Show fit	C-terminal binding protein 2
chr2_+_200306048 Show fit	9.73	ENST00000409988.7 ENST00000409385.5	SPATS2L Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated serine rich 2 like
chr3_-_185824966 Show fit	9.60	ENST00000457616.6 ENST00000346192.7	IGF2BP2 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor 2 mRNA binding protein 2
chr11_+_46381033 Show fit	9.47	ENST00000359803.7	MDK Ensembl NCBI GeneCards UniProt Show fit	midkine
chr10_-_125160499 Show fit	9.17	ENST00000494626.6 ENST00000337195.9	CTBP2 Ensembl NCBI GeneCards UniProt Show fit	C-terminal binding protein 2
chr12_+_6200351 Show fit	9.09	ENST00000679331.1 ENST00000382519.9 ENST00000009180.10 ENST00000536586.7	CD9 Ensembl NCBI GeneCards UniProt Show fit	CD9 molecule
chr7_+_116499687 Show fit	9.04	ENST00000222693.5 ENST00000343213.2	CAV2 Ensembl NCBI GeneCards UniProt Show fit	caveolin 2
chr3_-_185825029 Show fit	9.00	ENST00000382199.7	IGF2BP2 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor 2 mRNA binding protein 2
chr6_+_82364234 Show fit	8.92	ENST00000543496.3	TPBG Ensembl NCBI GeneCards UniProt Show fit	trophoblast glycoprotein
chr11_+_46381698 Show fit	8.84	ENST00000395565.5	MDK Ensembl NCBI GeneCards UniProt Show fit	midkine
chr10_-_95290992 Show fit	8.16	ENST00000329399.7	PDLIM1 Ensembl NCBI GeneCards UniProt Show fit	PDZ and LIM domain 1
chr2_-_20225083 Show fit	8.13	ENST00000403076.5	SDC1 Ensembl NCBI GeneCards UniProt Show fit	syndecan 1
chr2_-_177264686 Show fit	7.97	ENST00000397062.8 ENST00000430047.1	NFE2L2 Ensembl NCBI GeneCards UniProt Show fit	nuclear factor, erythroid 2 like 2
chr12_-_55728640 Show fit	7.93	ENST00000551173.5 ENST00000420846.7	CD63 Ensembl NCBI GeneCards UniProt Show fit	CD63 molecule
chr12_-_55728994 Show fit	7.78	ENST00000257857.9	CD63 Ensembl NCBI GeneCards UniProt Show fit	CD63 molecule
chrX_+_136147465 Show fit	7.55	ENST00000651929.2	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr4_-_39527429 Show fit	7.54	ENST00000501493.6 ENST00000509391.1 ENST00000316423.11 ENST00000507089.5	UGDH Ensembl NCBI GeneCards UniProt Show fit	UDP-glucose 6-dehydrogenase
chr10_+_17229267 Show fit	7.46	ENST00000224237.9	VIM Ensembl NCBI GeneCards UniProt Show fit	vimentin
chr21_+_45981736 Show fit	7.42	ENST00000361866.8	COL6A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type VI alpha 1 chain
chr12_+_51391273 Show fit	7.35	ENST00000535225.6 ENST00000358657.7	SLC4A8 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 4 member 8
chrX_+_136147525 Show fit	7.25	ENST00000652745.1 ENST00000627578.2 ENST00000652457.1 ENST00000394155.8 ENST00000618438.4	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr5_+_102754631 Show fit	7.15	ENST00000510208.2	PAM Ensembl NCBI GeneCards UniProt Show fit	peptidylglycine alpha-amidating monooxygenase
chr6_-_10412367 Show fit	7.11	ENST00000379608.9	TFAP2A Ensembl NCBI GeneCards UniProt Show fit	transcription factor AP-2 alpha
chr9_-_14322320 Show fit	7.03	ENST00000606230.2	NFIB Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I B
chr2_-_20225123 Show fit	7.03	ENST00000254351.9	SDC1 Ensembl NCBI GeneCards UniProt Show fit	syndecan 1
chr12_-_55728977 Show fit	6.94	ENST00000552164.5	CD63 Ensembl NCBI GeneCards UniProt Show fit	CD63 molecule
chr2_-_109614143 Show fit	6.92	ENST00000356688.8	SEPTIN10 Ensembl NCBI GeneCards UniProt Show fit	septin 10
chr15_+_96332432 Show fit	6.90	ENST00000559679.1 ENST00000394171.6	NR2F2 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 2 group F member 2
chr7_+_116525524 Show fit	6.89	ENST00000405348.6	CAV1 Ensembl NCBI GeneCards UniProt Show fit	caveolin 1
chr19_-_11197516 Show fit	6.88	ENST00000592903.5 ENST00000586659.6 ENST00000589359.5 ENST00000588724.5	KANK2 Ensembl NCBI GeneCards UniProt Show fit	KN motif and ankyrin repeat domains 2
chr9_-_21994345 Show fit	6.86	ENST00000579755.2 ENST00000530628.2	CDKN2A Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase inhibitor 2A
chr10_-_28303051 Show fit	6.86	ENST00000683449.1	MPP7 Ensembl NCBI GeneCards UniProt Show fit	membrane palmitoylated protein 7
chrX_-_107000185 Show fit	6.85	ENST00000355610.9	MORC4 Ensembl NCBI GeneCards UniProt Show fit	MORC family CW-type zinc finger 4
chr12_-_50283472 Show fit	6.80	ENST00000551691.5 ENST00000394943.7 ENST00000341247.8	LIMA1 Ensembl NCBI GeneCards UniProt Show fit	LIM domain and actin binding 1
chr11_+_57753243 Show fit	6.71	ENST00000524630.5 ENST00000529919.5 ENST00000533189.1	CTNND1 Ensembl NCBI GeneCards UniProt Show fit	catenin delta 1
chr3_-_136752361 Show fit	6.69	ENST00000480733.1 ENST00000629124.2 ENST00000383202.7 ENST00000236698.9 ENST00000434713.6	STAG1 Ensembl NCBI GeneCards UniProt Show fit	stromal antigen 1
chr11_+_75562056 Show fit	6.66	ENST00000533603.5	SERPINH1 Ensembl NCBI GeneCards UniProt Show fit	serpin family H member 1
chr9_-_14314132 Show fit	6.55	ENST00000380953.6	NFIB Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I B
chr5_+_138753412 Show fit	6.48	ENST00000520339.5 ENST00000627109.2 ENST00000302763.12 ENST00000518910.5	CTNNA1 Ensembl NCBI GeneCards UniProt Show fit	catenin alpha 1
chr13_-_110307131 Show fit	6.47	ENST00000543140.6 ENST00000375820.10	COL4A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type IV alpha 1 chain
chr9_-_14313642 Show fit	6.42	ENST00000637742.1	NFIB Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I B
chr3_+_172040554 Show fit	6.42	ENST00000336824.8 ENST00000423424.5	FNDC3B Ensembl NCBI GeneCards UniProt Show fit	fibronectin type III domain containing 3B
chr1_-_94541636 Show fit	6.41	ENST00000370207.4	F3 Ensembl NCBI GeneCards UniProt Show fit	coagulation factor III, tissue factor
chr3_-_98901656 Show fit	6.37	ENST00000326840.11	DCBLD2 Ensembl NCBI GeneCards UniProt Show fit	discoidin, CUB and LCCL domain containing 2
chrX_-_133985449 Show fit	6.29	ENST00000631057.2	GPC3 Ensembl NCBI GeneCards UniProt Show fit	glypican 3
chr11_-_2929412 Show fit	6.27	ENST00000314222.5	PHLDA2 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology like domain family A member 2
chrX_-_40735476 Show fit	6.25	ENST00000324817.6	MED14 Ensembl NCBI GeneCards UniProt Show fit	mediator complex subunit 14
chr11_+_46381753 Show fit	6.23	ENST00000407067.1	MDK Ensembl NCBI GeneCards UniProt Show fit	midkine
chr2_+_36355712 Show fit	6.18	ENST00000280527.7	CRIM1 Ensembl NCBI GeneCards UniProt Show fit	cysteine rich transmembrane BMP regulator 1
chr15_-_29822418 Show fit	6.05	ENST00000614355.5 ENST00000495972.6 ENST00000346128.10	TJP1 Ensembl NCBI GeneCards UniProt Show fit	tight junction protein 1
chr20_-_45348414 Show fit	6.04	ENST00000372733.3	SDC4 Ensembl NCBI GeneCards UniProt Show fit	syndecan 4
chr5_+_176238365 Show fit	6.01	ENST00000341199.10 ENST00000430704.6 ENST00000443967.5 ENST00000429602.7	SIMC1 Ensembl NCBI GeneCards UniProt Show fit	SUMO interacting motifs containing 1
chr9_+_71911468 Show fit	5.98	ENST00000377031.7	C9orf85 Ensembl NCBI GeneCards UniProt Show fit	chromosome 9 open reading frame 85
chr12_-_15789375 Show fit	5.94	ENST00000544064.1 ENST00000642939.1 ENST00000281172.10 ENST00000543523.5 ENST00000644374.1 ENST00000645775.1 ENST00000642278.1 ENST00000646123.1 ENST00000536793.5	EPS8 Ensembl NCBI GeneCards UniProt Show fit	epidermal growth factor receptor pathway substrate 8
chr8_-_25458389 Show fit	5.93	ENST00000221200.9	KCTD9 Ensembl NCBI GeneCards UniProt Show fit	potassium channel tetramerization domain containing 9
chr15_-_75451650 Show fit	5.93	ENST00000567289.5 ENST00000394947.8 ENST00000565264.1	SIN3A Ensembl NCBI GeneCards UniProt Show fit	SIN3 transcription regulator family member A
chr15_-_60397964 Show fit	5.88	ENST00000558998.5 ENST00000560165.5 ENST00000557986.5 ENST00000559467.5 ENST00000677968.1 ENST00000678450.1 ENST00000332680.8 ENST00000396024.7 ENST00000557906.6 ENST00000558558.6 ENST00000559113.6 ENST00000559780.6 ENST00000559956.6 ENST00000560468.6 ENST00000678870.1 ENST00000678061.1 ENST00000451270.7 ENST00000421017.6 ENST00000560466.5 ENST00000558132.5 ENST00000559370.5 ENST00000559725.5 ENST00000558985.6 ENST00000679109.1	ANXA2 Ensembl NCBI GeneCards UniProt Show fit	annexin A2
chr2_+_200306519 Show fit	5.82	ENST00000360760.9	SPATS2L Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated serine rich 2 like
chr2_+_186590022 Show fit	5.80	ENST00000261023.8 ENST00000374907.7	ITGAV Ensembl NCBI GeneCards UniProt Show fit	integrin subunit alpha V
chr15_+_44288701 Show fit	5.80	ENST00000299957.11 ENST00000559222.5 ENST00000650436.1	GOLM2 Ensembl NCBI GeneCards UniProt Show fit	golgi membrane protein 2
chr3_+_37861926 Show fit	5.79	ENST00000443503.6	CTDSPL Ensembl NCBI GeneCards UniProt Show fit	CTD small phosphatase like
chr16_-_10580577 Show fit	5.78	ENST00000359543.8	EMP2 Ensembl NCBI GeneCards UniProt Show fit	epithelial membrane protein 2
chr16_-_31074193 Show fit	5.76	ENST00000300849.5	ZNF668 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 668
chr14_-_52950992 Show fit	5.71	ENST00000343279.8 ENST00000399304.7 ENST00000395631.6 ENST00000341590.8	FERMT2 Ensembl NCBI GeneCards UniProt Show fit	fermitin family member 2
chr18_+_31498168 Show fit	5.64	ENST00000261590.13 ENST00000585206.1 ENST00000683654.1	DSG2 Ensembl NCBI GeneCards UniProt Show fit	desmoglein 2
chr21_+_46098102 Show fit	5.63	ENST00000300527.9 ENST00000310645.9	COL6A2 Ensembl NCBI GeneCards UniProt Show fit	collagen type VI alpha 2 chain
chr1_-_112707314 Show fit	5.62	ENST00000369642.7	RHOC Ensembl NCBI GeneCards UniProt Show fit	ras homolog family member C
chrX_+_43654888 Show fit	5.53	ENST00000542639.5	MAOA Ensembl NCBI GeneCards UniProt Show fit	monoamine oxidase A
chr3_+_37861849 Show fit	5.52	ENST00000273179.10	CTDSPL Ensembl NCBI GeneCards UniProt Show fit	CTD small phosphatase like
chr10_-_77926724 Show fit	5.51	ENST00000372391.7	DLG5 Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 5
chr15_+_63048535 Show fit	5.49	ENST00000560959.5	TPM1 Ensembl NCBI GeneCards UniProt Show fit	tropomyosin 1
chr8_+_94641074 Show fit	5.46	ENST00000423620.6	ESRP1 Ensembl NCBI GeneCards UniProt Show fit	epithelial splicing regulatory protein 1
chr15_+_63048658 Show fit	5.43	ENST00000560615.5 ENST00000651577.1	TPM1 Ensembl NCBI GeneCards UniProt Show fit	tropomyosin 1
chr13_+_73058993 Show fit	5.43	ENST00000377687.6	KLF5 Ensembl NCBI GeneCards UniProt Show fit	Kruppel like factor 5
chr8_+_94641199 Show fit	5.30	ENST00000646773.1 ENST00000454170.7	ESRP1 Ensembl NCBI GeneCards UniProt Show fit	epithelial splicing regulatory protein 1
chr15_+_63048436 Show fit	5.27	ENST00000334895.10 ENST00000404484.9 ENST00000558910.3 ENST00000317516.12	TPM1 Ensembl NCBI GeneCards UniProt Show fit	tropomyosin 1
chr14_-_104978360 Show fit	5.26	ENST00000333244.6	AHNAK2 Ensembl NCBI GeneCards UniProt Show fit	AHNAK nucleoprotein 2
chr2_+_109614328 Show fit	5.26	ENST00000356454.5	SOWAHC Ensembl NCBI GeneCards UniProt Show fit	sosondowah ankyrin repeat domain family member C
chr14_-_37595224 Show fit	5.25	ENST00000250448.5	FOXA1 Ensembl NCBI GeneCards UniProt Show fit	forkhead box A1
chr14_-_91060578 Show fit	5.22	ENST00000418736.6 ENST00000614987.5	RPS6KA5 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A5
chr14_-_68979076 Show fit	5.22	ENST00000538545.6 ENST00000684639.1	ACTN1 Ensembl NCBI GeneCards UniProt Show fit	actinin alpha 1
chr1_-_243850216 Show fit	5.22	ENST00000673466.1	AKT3 Ensembl NCBI GeneCards UniProt Show fit	AKT serine/threonine kinase 3
chr2_+_200306340 Show fit	5.21	ENST00000451764.6	SPATS2L Ensembl NCBI GeneCards UniProt Show fit	spermatogenesis associated serine rich 2 like
chr1_+_156082563 Show fit	5.21	ENST00000368301.6	LMNA Ensembl NCBI GeneCards UniProt Show fit	lamin A/C
chr12_-_79690957 Show fit	5.17	ENST00000328827.9	PAWR Ensembl NCBI GeneCards UniProt Show fit	pro-apoptotic WT1 regulator
chr17_-_3668557 Show fit	5.17	ENST00000225525.4	TAX1BP3 Ensembl NCBI GeneCards UniProt Show fit	Tax1 binding protein 3
chr8_+_94641145 Show fit	5.17	ENST00000433389.8 ENST00000358397.9	ESRP1 Ensembl NCBI GeneCards UniProt Show fit	epithelial splicing regulatory protein 1
chr2_-_173964180 Show fit	5.10	ENST00000418194.7	SP3 Ensembl NCBI GeneCards UniProt Show fit	Sp3 transcription factor
chr5_-_147510056 Show fit	5.05	ENST00000343218.10	DPYSL3 Ensembl NCBI GeneCards UniProt Show fit	dihydropyrimidinase like 3
chr20_+_45469745 Show fit	4.99	ENST00000372676.8 ENST00000217425.9 ENST00000339946.7	WFDC2 Ensembl NCBI GeneCards UniProt Show fit	WAP four-disulfide core domain 2
chr1_-_154974361 Show fit	4.86	ENST00000368453.8 ENST00000368450.5	SHC1 Ensembl NCBI GeneCards UniProt Show fit	SHC adaptor protein 1
chr9_+_134641768 Show fit	4.82	ENST00000371817.8 ENST00000618395.4	COL5A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type V alpha 1 chain
chrX_+_136147556 Show fit	4.82	ENST00000651089.1 ENST00000420362.5	FHL1 Ensembl NCBI GeneCards UniProt Show fit	four and a half LIM domains 1
chr2_+_172427662 Show fit	4.81	ENST00000264107.12 ENST00000458358.5	ITGA6 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit alpha 6
chr9_-_14314067 Show fit	4.80	ENST00000397575.7	NFIB Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I B
chr7_-_130440848 Show fit	4.77	ENST00000675803.1 ENST00000223208.10 ENST00000343969.10 ENST00000471201.6 ENST00000675649.1 ENST00000675168.1 ENST00000469826.2 ENST00000334451.6 ENST00000675962.1 ENST00000675563.1 ENST00000480206.2 ENST00000489512.5 ENST00000676243.1 ENST00000674539.1 ENST00000675935.1	CEP41 Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 41
chr1_+_113979391 Show fit	4.76	ENST00000393300.6 ENST00000369551.5	OLFML3 Ensembl NCBI GeneCards UniProt Show fit	olfactomedin like 3
chr15_-_29821473 Show fit	4.75	ENST00000400011.6	TJP1 Ensembl NCBI GeneCards UniProt Show fit	tight junction protein 1
chr2_-_210171327 Show fit	4.75	ENST00000418791.5 ENST00000452086.5	KANSL1L Ensembl NCBI GeneCards UniProt Show fit	KAT8 regulatory NSL complex subunit 1 like
chr2_-_63588390 Show fit	4.72	ENST00000272321.12 ENST00000409562.7	WDPCP Ensembl NCBI GeneCards UniProt Show fit	WD repeat containing planar cell polarity effector
chr12_+_53050014 Show fit	4.71	ENST00000314250.11	TNS2 Ensembl NCBI GeneCards UniProt Show fit	tensin 2
chr10_-_32957865 Show fit	4.68	ENST00000437302.6 ENST00000396033.6	ITGB1 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit beta 1
chr9_-_23821809 Show fit	4.62	ENST00000544538.5	ELAVL2 Ensembl NCBI GeneCards UniProt Show fit	ELAV like RNA binding protein 2
chr16_-_30526518 Show fit	4.62	ENST00000380412.7	ZNF768 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 768
chr11_-_62601818 Show fit	4.60	ENST00000278823.7	MTA2 Ensembl NCBI GeneCards UniProt Show fit	metastasis associated 1 family member 2
chr15_+_44288757 Show fit	4.57	ENST00000345795.6	GOLM2 Ensembl NCBI GeneCards UniProt Show fit	golgi membrane protein 2
chr16_+_31472130 Show fit	4.57	ENST00000394863.8 ENST00000565360.5 ENST00000361773.7	TGFB1I1 Ensembl NCBI GeneCards UniProt Show fit	transforming growth factor beta 1 induced transcript 1
chr11_+_92224801 Show fit	4.56	ENST00000525166.6	FAT3 Ensembl NCBI GeneCards UniProt Show fit	FAT atypical cadherin 3
chr3_+_138947210 Show fit	4.55	ENST00000383165.4	FOXL2NB Ensembl NCBI GeneCards UniProt Show fit	FOXL2 neighbor
chr12_+_53050179 Show fit	4.55	ENST00000546602.5 ENST00000552570.5 ENST00000549700.5	TNS2 Ensembl NCBI GeneCards UniProt Show fit	tensin 2
chr9_-_14313843 Show fit	4.52	ENST00000636063.1 ENST00000380921.3 ENST00000622520.1 ENST00000380959.7	NFIB Ensembl NCBI GeneCards UniProt Show fit	nuclear factor I B
chr10_+_87659839 Show fit	4.46	ENST00000456849.2	PAPSS2 Ensembl NCBI GeneCards UniProt Show fit	3'-phosphoadenosine 5'-phosphosulfate synthase 2
chrX_-_133415478 Show fit	4.43	ENST00000370828.4	GPC4 Ensembl NCBI GeneCards UniProt Show fit	glypican 4
chr2_-_218010202 Show fit	4.41	ENST00000646520.1	TNS1 Ensembl NCBI GeneCards UniProt Show fit	tensin 1
chr12_-_76031588 Show fit	4.41	ENST00000602540.5	PHLDA1 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin homology like domain family A member 1
chr6_-_106974721 Show fit	4.41	ENST00000606017.2 ENST00000620405.1	CD24 Ensembl NCBI GeneCards UniProt Show fit	CD24 molecule
chr1_+_113979460 Show fit	4.40	ENST00000320334.5	OLFML3 Ensembl NCBI GeneCards UniProt Show fit	olfactomedin like 3
chrX_-_133985574 Show fit	4.40	ENST00000394299.7 ENST00000370818.8	GPC3 Ensembl NCBI GeneCards UniProt Show fit	glypican 3
chr9_+_2622053 Show fit	4.40	ENST00000681306.1 ENST00000681618.1	VLDLR Ensembl NCBI GeneCards UniProt Show fit	very low density lipoprotein receptor
chr12_-_55729660 Show fit	4.38	ENST00000546457.1 ENST00000549117.5	CD63 Ensembl NCBI GeneCards UniProt Show fit	CD63 molecule
chr11_+_46380746 Show fit	4.37	ENST00000405308.6	MDK Ensembl NCBI GeneCards UniProt Show fit	midkine
chr1_-_94927079 Show fit	4.37	ENST00000370206.9 ENST00000394202.8	CNN3 Ensembl NCBI GeneCards UniProt Show fit	calponin 3
chr16_+_69132590 Show fit	4.36	ENST00000562237.5 ENST00000567460.5 ENST00000566227.5 ENST00000314423.12 ENST00000352319.8 ENST00000563094.5	UTP4 Ensembl NCBI GeneCards UniProt Show fit	UTP4 small subunit processome component
chr12_+_53938824 Show fit	4.36	ENST00000243056.5	HOXC13 Ensembl NCBI GeneCards UniProt Show fit	homeobox C13
chr1_+_67685342 Show fit	4.36	ENST00000617962.2	GADD45A Ensembl NCBI GeneCards UniProt Show fit	growth arrest and DNA damage inducible alpha
chrX_-_100636799 Show fit	4.34	ENST00000373020.9	TSPAN6 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 6
chrX_+_119236245 Show fit	4.34	ENST00000535419.2	PGRMC1 Ensembl NCBI GeneCards UniProt Show fit	progesterone receptor membrane component 1
chrX_+_119236274 Show fit	4.33	ENST00000217971.8	PGRMC1 Ensembl NCBI GeneCards UniProt Show fit	progesterone receptor membrane component 1
chr12_-_47079926 Show fit	4.32	ENST00000429635.1 ENST00000550413.2	AMIGO2 Ensembl NCBI GeneCards UniProt Show fit	adhesion molecule with Ig like domain 2
chr9_+_124777098 Show fit	4.31	ENST00000373580.8	OLFML2A Ensembl NCBI GeneCards UniProt Show fit	olfactomedin like 2A
chr2_-_173964069 Show fit	4.31	ENST00000652005.2	SP3 Ensembl NCBI GeneCards UniProt Show fit	Sp3 transcription factor
chr20_+_19758245 Show fit	4.30	ENST00000255006.12	RIN2 Ensembl NCBI GeneCards UniProt Show fit	Ras and Rab interactor 2
chr10_-_31928790 Show fit	4.29	ENST00000375250.9 ENST00000344936.7	ARHGAP12 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 12
chrX_-_108736556 Show fit	4.26	ENST00000372129.4	IRS4 Ensembl NCBI GeneCards UniProt Show fit	insulin receptor substrate 4
chr12_-_47079859 Show fit	4.23	ENST00000266581.4	AMIGO2 Ensembl NCBI GeneCards UniProt Show fit	adhesion molecule with Ig like domain 2
chr8_+_97869040 Show fit	4.23	ENST00000254898.7 ENST00000524308.5 ENST00000522025.6	MATN2 Ensembl NCBI GeneCards UniProt Show fit	matrilin 2
chr19_-_40690629 Show fit	4.21	ENST00000252891.8	NUMBL Ensembl NCBI GeneCards UniProt Show fit	NUMB like endocytic adaptor protein
chr7_-_140478975 Show fit	4.19	ENST00000474576.5 ENST00000473444.1 ENST00000471104.5	MKRN1 Ensembl NCBI GeneCards UniProt Show fit	makorin ring finger protein 1
chr14_+_94174284 Show fit	4.18	ENST00000304338.8	PPP4R4 Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 4 regulatory subunit 4
chr7_-_19117625 Show fit	4.18	ENST00000242261.6	TWIST1 Ensembl NCBI GeneCards UniProt Show fit	twist family bHLH transcription factor 1
chr2_-_20051610 Show fit	4.15	ENST00000175091.5	LAPTM4A Ensembl NCBI GeneCards UniProt Show fit	lysosomal protein transmembrane 4 alpha
chr1_-_151993822 Show fit	4.14	ENST00000368811.8	S100A10 Ensembl NCBI GeneCards UniProt Show fit	S100 calcium binding protein A10
chr12_+_106774630 Show fit	4.14	ENST00000392839.6 ENST00000548914.5 ENST00000355478.6 ENST00000552619.1 ENST00000549643.5 ENST00000392837.9	RIC8B Ensembl NCBI GeneCards UniProt Show fit	RIC8 guanine nucleotide exchange factor B
chr7_+_17298642 Show fit	4.13	ENST00000242057.9	AHR Ensembl NCBI GeneCards UniProt Show fit	aryl hydrocarbon receptor
chr1_+_183023409 Show fit	4.08	ENST00000258341.5	LAMC1 Ensembl NCBI GeneCards UniProt Show fit	laminin subunit gamma 1
chr19_+_41708585 Show fit	4.08	ENST00000398599.8 ENST00000221992.11	CEACAM5 Ensembl NCBI GeneCards UniProt Show fit	CEA cell adhesion molecule 5
chr10_-_31928864 Show fit	4.08	ENST00000375245.8 ENST00000396144.8	ARHGAP12 Ensembl NCBI GeneCards UniProt Show fit	Rho GTPase activating protein 12
chr20_-_18057841 Show fit	4.07	ENST00000278780.7	OVOL2 Ensembl NCBI GeneCards UniProt Show fit	ovo like zinc finger 2
chr11_+_75562274 Show fit	4.07	ENST00000532356.5 ENST00000524558.5	SERPINH1 Ensembl NCBI GeneCards UniProt Show fit	serpin family H member 1
chr19_+_54137740 Show fit	4.07	ENST00000644245.1 ENST00000646002.1 ENST00000221232.11 ENST00000440571.6 ENST00000617930.2	CNOT3 Ensembl NCBI GeneCards UniProt Show fit	CCR4-NOT transcription complex subunit 3
chr17_-_50866347 Show fit	4.03	ENST00000499247.3	TOB1 Ensembl NCBI GeneCards UniProt Show fit	transducer of ERBB2, 1
chr2_+_197500371 Show fit	4.02	ENST00000409468.1 ENST00000233893.10	HSPE1 Ensembl NCBI GeneCards UniProt Show fit	heat shock protein family E (Hsp10) member 1
chr7_+_74453790 Show fit	4.01	ENST00000265755.7 ENST00000424337.7 ENST00000455841.6	GTF2IRD1 Ensembl NCBI GeneCards UniProt Show fit	GTF2I repeat domain containing 1
chr5_+_102755269 Show fit	4.01	ENST00000304400.12 ENST00000455264.7 ENST00000684529.1 ENST00000438793.8 ENST00000682882.1 ENST00000682972.1 ENST00000348126.7 ENST00000512073.1	PAM Ensembl NCBI GeneCards UniProt Show fit	peptidylglycine alpha-amidating monooxygenase
chr17_-_15341577 Show fit	3.99	ENST00000543896.1 ENST00000395930.6 ENST00000539245.5 ENST00000539316.1	TEKT3 Ensembl NCBI GeneCards UniProt Show fit	tektin 3
chrX_-_110795765 Show fit	3.99	ENST00000372045.5 ENST00000394797.8 ENST00000372042.6 ENST00000482160.5 ENST00000444321.2	CHRDL1 Ensembl NCBI GeneCards UniProt Show fit	chordin like 1
chr7_-_131556602 Show fit	3.98	ENST00000322985.9 ENST00000378555.8	PODXL Ensembl NCBI GeneCards UniProt Show fit	podocalyxin like
chr6_-_81752671 Show fit	3.97	ENST00000320172.11 ENST00000369754.7 ENST00000369756.3	TENT5A Ensembl NCBI GeneCards UniProt Show fit	terminal nucleotidyltransferase 5A
chr7_+_816609 Show fit	3.97	ENST00000457378.6 ENST00000389574.7 ENST00000452783.6 ENST00000435699.5 ENST00000440380.5 ENST00000439679.5 ENST00000424128.5	SUN1 Ensembl NCBI GeneCards UniProt Show fit	Sad1 and UNC84 domain containing 1
chr5_-_79991237 Show fit	3.96	ENST00000512560.5 ENST00000509852.6 ENST00000512528.3 ENST00000617335.4	MTX3 Ensembl NCBI GeneCards UniProt Show fit	metaxin 3
chr3_+_12287859 Show fit	3.95	ENST00000309576.11 ENST00000397015.7	PPARG Ensembl NCBI GeneCards UniProt Show fit	peroxisome proliferator activated receptor gamma
chr18_+_76822521 Show fit	3.94	ENST00000320610.14	ZNF236 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 236
chr1_+_228165794 Show fit	3.94	ENST00000366711.4	IBA57 Ensembl NCBI GeneCards UniProt Show fit	iron-sulfur cluster assembly factor IBA57
chr11_+_75562242 Show fit	3.93	ENST00000526397.5 ENST00000529643.1 ENST00000525492.5 ENST00000530284.5 ENST00000358171.8	SERPINH1 Ensembl NCBI GeneCards UniProt Show fit	serpin family H member 1
chr10_-_17617326 Show fit	3.91	ENST00000326961.6 ENST00000361271.8	HACD1 Ensembl NCBI GeneCards UniProt Show fit	3-hydroxyacyl-CoA dehydratase 1
chr8_-_120445140 Show fit	3.91	ENST00000306185.8	MRPL13 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L13
chrX_-_38220824 Show fit	3.87	ENST00000378533.4 ENST00000432886.6 ENST00000544439.5 ENST00000538295.5	SRPX Ensembl NCBI GeneCards UniProt Show fit	sushi repeat containing protein X-linked
chr19_+_15107369 Show fit	3.83	ENST00000342784.7 ENST00000597977.5 ENST00000600440.5	SYDE1 Ensembl NCBI GeneCards UniProt Show fit	synapse defective Rho GTPase homolog 1
chr2_-_70553638 Show fit	3.81	ENST00000444975.5 ENST00000445399.5 ENST00000295400.11 ENST00000418333.6	TGFA Ensembl NCBI GeneCards UniProt Show fit	transforming growth factor alpha
chr1_-_243850070 Show fit	3.80	ENST00000366539.6 ENST00000672578.1	AKT3 Ensembl NCBI GeneCards UniProt Show fit	AKT serine/threonine kinase 3
chr15_+_100879822 Show fit	3.80	ENST00000329841.10 ENST00000557963.1 ENST00000346623.6	ALDH1A3 Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 1 family member A3
chr17_-_15999689 Show fit	3.78	ENST00000399277.6	ZSWIM7 Ensembl NCBI GeneCards UniProt Show fit	zinc finger SWIM-type containing 7
chr13_-_44576319 Show fit	3.73	ENST00000458659.3	TSC22D1 Ensembl NCBI GeneCards UniProt Show fit	TSC22 domain family member 1
chr17_-_3668640 Show fit	3.72	ENST00000611779.4	TAX1BP3 Ensembl NCBI GeneCards UniProt Show fit	Tax1 binding protein 3
chr16_+_67431112 Show fit	3.71	ENST00000326152.6	HSD11B2 Ensembl NCBI GeneCards UniProt Show fit	hydroxysteroid 11-beta dehydrogenase 2
chr9_-_23821275 Show fit	3.70	ENST00000380110.8	ELAVL2 Ensembl NCBI GeneCards UniProt Show fit	ELAV like RNA binding protein 2
chr12_-_48004496 Show fit	3.70	ENST00000337299.7	COL2A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type II alpha 1 chain
chr1_-_153986329 Show fit	3.70	ENST00000368575.5	RAB13 Ensembl NCBI GeneCards UniProt Show fit	RAB13, member RAS oncogene family
chr15_-_29822077 Show fit	3.69	ENST00000677774.1	TJP1 Ensembl NCBI GeneCards UniProt Show fit	tight junction protein 1
chr2_-_64019367 Show fit	3.69	ENST00000272322.9	VPS54 Ensembl NCBI GeneCards UniProt Show fit	VPS54 subunit of GARP complex
chr1_+_93448155 Show fit	3.69	ENST00000370253.6	FNBP1L Ensembl NCBI GeneCards UniProt Show fit	formin binding protein 1 like
chr8_-_66613208 Show fit	3.69	ENST00000522677.8	MYBL1 Ensembl NCBI GeneCards UniProt Show fit	MYB proto-oncogene like 1
chr17_+_50056095 Show fit	3.66	ENST00000320031.13	ITGA3 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit alpha 3
chr3_+_46883337 Show fit	3.66	ENST00000313049.9	PTH1R Ensembl NCBI GeneCards UniProt Show fit	parathyroid hormone 1 receptor
chr2_+_172427573 Show fit	3.65	ENST00000684293.1 ENST00000409080.6 ENST00000442250.6	ITGA6 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit alpha 6
chr1_+_244835616 Show fit	3.63	ENST00000366528.3 ENST00000411948.7	COX20 Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase assembly factor COX20
chrX_+_147912039 Show fit	3.62	ENST00000334557.10 ENST00000439526.6	FMR1 Ensembl NCBI GeneCards UniProt Show fit	FMRP translational regulator 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.7	38.8	GO:1900085	negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
7.7	54.2	GO:0030421	defecation(GO:0030421)
4.9	19.4	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
3.8	11.5	GO:0052047	interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
3.8	15.2	GO:0048627	myoblast development(GO:0048627)
3.8	18.8	GO:0003065	positive regulation of heart rate by epinephrine(GO:0003065)
3.5	17.3	GO:1901350	cell-cell signaling involved in cell-cell junction organization(GO:1901350)
3.4	6.8	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
3.4	13.6	GO:0003409	optic cup structural organization(GO:0003409)
2.9	32.4	GO:0021740	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
2.9	8.6	GO:1901254	modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
2.8	11.2	GO:0001519	peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
2.7	10.7	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
2.6	7.8	GO:1901420	negative regulation of response to alcohol(GO:1901420)
2.6	5.2	GO:0060434	bronchus morphogenesis(GO:0060434)
2.6	7.8	GO:0016476	regulation of embryonic cell shape(GO:0016476)
2.4	9.6	GO:1904753	negative regulation of vascular associated smooth muscle cell migration(GO:1904753)
2.4	28.6	GO:0009414	response to water deprivation(GO:0009414)
2.2	6.5	GO:2001045	negative regulation of integrin-mediated signaling pathway(GO:2001045)
2.2	8.6	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
2.1	16.7	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
2.1	6.3	GO:2000793	cell proliferation involved in heart valve development(GO:2000793)
2.1	6.2	GO:0044861	protein transport into plasma membrane raft(GO:0044861)
2.1	12.4	GO:0071896	protein localization to adherens junction(GO:0071896)
2.0	6.1	GO:0061445	endocardial cell fate commitment(GO:0060957) endocardial cushion cell fate commitment(GO:0061445)
2.0	20.2	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
2.0	6.0	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
2.0	7.9	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
1.9	5.8	GO:0007037	vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
1.9	5.8	GO:0045715	negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
1.9	5.8	GO:1901674	histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
1.9	7.6	GO:1902528	regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
1.8	11.0	GO:1904274	tricellular tight junction assembly(GO:1904274)
1.8	9.0	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
1.8	5.3	GO:0044313	protein K6-linked deubiquitination(GO:0044313)
1.8	24.8	GO:2000680	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
1.7	6.9	GO:0009956	radial pattern formation(GO:0009956)
1.7	8.4	GO:0044111	development involved in symbiotic interaction(GO:0044111)
1.6	1.6	GO:1903526	negative regulation of membrane tubulation(GO:1903526)
1.6	8.2	GO:1903224	regulation of endodermal cell differentiation(GO:1903224) negative regulation of gastrulation(GO:2000542)
1.6	6.4	GO:0030047	actin modification(GO:0030047)
1.6	4.8	GO:0036071	N-glycan fucosylation(GO:0036071)
1.6	6.4	GO:0002541	activation of plasma proteins involved in acute inflammatory response(GO:0002541)
1.6	9.6	GO:0035105	sterol regulatory element binding protein import into nucleus(GO:0035105)
1.6	7.9	GO:0042986	positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
1.5	7.7	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
1.5	6.0	GO:0060061	Spemann organizer formation(GO:0060061)
1.5	3.0	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
1.5	8.8	GO:0003164	His-Purkinje system development(GO:0003164)
1.4	4.2	GO:0002368	B cell cytokine production(GO:0002368)
1.4	5.5	GO:0072166	posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302)
1.4	6.9	GO:0035986	senescence-associated heterochromatin focus assembly(GO:0035986)
1.4	4.1	GO:1903892	negative regulation of ATF6-mediated unfolded protein response(GO:1903892)
1.3	4.0	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
1.3	5.4	GO:0061358	negative regulation of Wnt protein secretion(GO:0061358)
1.3	9.4	GO:2000230	negative regulation of pancreatic stellate cell proliferation(GO:2000230)
1.3	4.0	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
1.3	5.2	GO:0033594	response to hydroxyisoflavone(GO:0033594)
1.3	6.4	GO:1904637	response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
1.3	6.3	GO:1902414	protein localization to cell junction(GO:1902414)
1.3	3.8	GO:0070384	olfactory pit development(GO:0060166) Harderian gland development(GO:0070384)
1.2	17.2	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
1.2	3.6	GO:0042412	taurine biosynthetic process(GO:0042412)
1.2	4.8	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
1.2	9.6	GO:0032534	regulation of microvillus assembly(GO:0032534)
1.2	3.5	GO:0014740	negative regulation of muscle hyperplasia(GO:0014740)
1.1	3.4	GO:0036166	phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
1.1	3.3	GO:0018211	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
1.1	3.3	GO:0015888	thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
1.1	26.4	GO:0051764	actin crosslink formation(GO:0051764)
1.1	4.4	GO:0032595	B cell receptor transport within lipid bilayer(GO:0032595) B cell receptor transport into membrane raft(GO:0032597) protein transport out of membrane raft(GO:0032599) chemokine receptor transport out of membrane raft(GO:0032600) negative regulation of transforming growth factor beta3 production(GO:0032913) chemokine receptor transport within lipid bilayer(GO:0033606)
1.1	2.2	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
1.1	6.5	GO:0006065	UDP-glucuronate biosynthetic process(GO:0006065)
1.1	6.5	GO:0072236	metanephric loop of Henle development(GO:0072236)
1.1	5.4	GO:0070836	caveola assembly(GO:0070836)
1.1	5.4	GO:1990164	histone H2A phosphorylation(GO:1990164)
1.1	5.3	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
1.0	3.1	GO:0031550	positive regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031550)
1.0	1.0	GO:0048807	female genitalia morphogenesis(GO:0048807)
1.0	17.4	GO:0070208	protein heterotrimerization(GO:0070208)
1.0	4.1	GO:1904849	positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
1.0	4.1	GO:0060214	endocardium formation(GO:0060214)
1.0	3.0	GO:0060278	regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
1.0	1.0	GO:0048843	negative regulation of axon extension involved in axon guidance(GO:0048843)
1.0	14.9	GO:0035878	nail development(GO:0035878)
1.0	4.0	GO:0080154	regulation of fertilization(GO:0080154)
1.0	3.0	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
1.0	3.9	GO:0021759	globus pallidus development(GO:0021759)
1.0	4.8	GO:0021997	neural plate axis specification(GO:0021997)
1.0	1.0	GO:1904048	regulation of spontaneous neurotransmitter secretion(GO:1904048)
1.0	2.9	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
1.0	9.6	GO:0043353	enucleate erythrocyte differentiation(GO:0043353)
0.9	0.9	GO:0060596	mammary placode formation(GO:0060596)
0.9	11.2	GO:0000733	DNA strand renaturation(GO:0000733)
0.9	8.4	GO:0089700	protein kinase D signaling(GO:0089700)
0.9	6.5	GO:0046929	negative regulation of neurotransmitter secretion(GO:0046929)
0.9	6.3	GO:0035290	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.9	0.9	GO:0061032	visceral serous pericardium development(GO:0061032)
0.9	3.6	GO:1902463	protein localization to cell leading edge(GO:1902463)
0.9	11.6	GO:0045794	response to carbon monoxide(GO:0034465) negative regulation of cell volume(GO:0045794)
0.9	3.5	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.9	2.6	GO:0000103	sulfate assimilation(GO:0000103)
0.9	3.4	GO:1990834	response to odorant(GO:1990834)
0.9	4.3	GO:0061364	apoptotic process involved in luteolysis(GO:0061364)
0.9	1.7	GO:0003358	noradrenergic neuron development(GO:0003358)
0.8	0.8	GO:0038065	collagen-activated signaling pathway(GO:0038065)
0.8	2.5	GO:0060392	negative regulation of SMAD protein import into nucleus(GO:0060392)
0.8	6.7	GO:0034436	glycoprotein transport(GO:0034436)
0.8	0.8	GO:0021637	trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.8	2.5	GO:0072365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.8	2.5	GO:0018395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine(GO:0018395) histone arginine demethylation(GO:0070077) histone H3-R2 demethylation(GO:0070078) histone H4-R3 demethylation(GO:0070079)
0.8	3.2	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.8	4.0	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.8	6.4	GO:0030473	nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473)
0.8	4.0	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.8	1.6	GO:0070172	positive regulation of tooth mineralization(GO:0070172)
0.8	3.1	GO:0086053	SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021) AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.8	2.4	GO:0060995	cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.8	0.8	GO:0031335	regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.8	8.5	GO:0070307	lens fiber cell development(GO:0070307)
0.8	6.9	GO:0060613	fat pad development(GO:0060613)
0.8	1.5	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.8	3.0	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.7	15.0	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.7	2.9	GO:0021502	neural fold elevation formation(GO:0021502)
0.7	6.5	GO:1900223	positive regulation of beta-amyloid clearance(GO:1900223)
0.7	2.2	GO:1902283	negative regulation of primary amine oxidase activity(GO:1902283)
0.7	14.2	GO:1904778	regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.7	13.3	GO:0019614	catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.7	2.8	GO:1904117	response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.7	0.7	GO:0071393	cellular response to progesterone stimulus(GO:0071393)
0.7	4.1	GO:0001765	membrane raft assembly(GO:0001765)
0.7	2.0	GO:0015798	myo-inositol transport(GO:0015798)
0.7	2.7	GO:0031443	fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.7	4.8	GO:0018095	protein polyglutamylation(GO:0018095)
0.7	2.0	GO:0048391	apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter urothelium development(GO:0072190) ureter epithelial cell differentiation(GO:0072192) ureter morphogenesis(GO:0072197) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007) negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137)
0.7	9.9	GO:0045793	positive regulation of cell size(GO:0045793)
0.7	2.0	GO:0003150	muscular septum morphogenesis(GO:0003150)
0.7	4.6	GO:0090210	regulation of establishment of blood-brain barrier(GO:0090210)
0.6	1.9	GO:0048104	establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.6	2.6	GO:0019401	glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.6	2.5	GO:0033484	nitric oxide homeostasis(GO:0033484)
0.6	2.5	GO:0006175	adenosine salvage(GO:0006169) dATP biosynthetic process(GO:0006175) purine deoxyribonucleoside triphosphate biosynthetic process(GO:0009216)
0.6	1.9	GO:1900275	negative regulation of phospholipase C activity(GO:1900275)
0.6	2.5	GO:0061107	seminal vesicle development(GO:0061107)
0.6	2.5	GO:0070295	renal water absorption(GO:0070295)
0.6	3.8	GO:0071910	determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
0.6	3.1	GO:1901911	diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.6	1.9	GO:0014813	skeletal muscle satellite cell commitment(GO:0014813)
0.6	2.5	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
0.6	8.1	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.6	1.8	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
0.6	3.0	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.6	5.9	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.6	1.8	GO:0006679	glucosylceramide biosynthetic process(GO:0006679) negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
0.6	1.2	GO:0036304	umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027)
0.6	0.6	GO:1990791	dorsal root ganglion development(GO:1990791)
0.6	2.3	GO:0003095	pressure natriuresis(GO:0003095)
0.6	0.6	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.6	12.5	GO:0031581	hemidesmosome assembly(GO:0031581)
0.6	1.7	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.6	1.7	GO:1904398	positive regulation of neuromuscular junction development(GO:1904398)
0.6	3.4	GO:1904781	positive regulation of protein localization to centrosome(GO:1904781)
0.6	9.0	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.6	3.3	GO:0006021	inositol biosynthetic process(GO:0006021)
0.6	2.8	GO:0010481	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.5	2.2	GO:0010643	cell communication by chemical coupling(GO:0010643)
0.5	8.7	GO:1902373	negative regulation of mRNA catabolic process(GO:1902373)
0.5	2.2	GO:0001826	inner cell mass cell differentiation(GO:0001826)
0.5	3.2	GO:0061143	alveolar primary septum development(GO:0061143)
0.5	0.5	GO:0010840	regulation of circadian sleep/wake cycle, wakefulness(GO:0010840) circadian sleep/wake cycle, wakefulness(GO:0042746)
0.5	9.5	GO:0060272	embryonic skeletal joint morphogenesis(GO:0060272)
0.5	2.1	GO:0072137	condensed mesenchymal cell proliferation(GO:0072137)
0.5	0.5	GO:1903911	positive regulation of receptor clustering(GO:1903911)
0.5	1.6	GO:1904440	antigen processing and presentation of peptide antigen via MHC class Ib(GO:0002428) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) cellular response to iron(III) ion(GO:0071283) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.5	6.8	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.5	2.6	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.5	2.6	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
0.5	3.1	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
0.5	3.1	GO:0032487	regulation of Rap protein signal transduction(GO:0032487)
0.5	3.1	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.5	1.5	GO:0009386	translational attenuation(GO:0009386)
0.5	1.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.5	4.6	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.5	1.5	GO:0021960	anterior commissure morphogenesis(GO:0021960)
0.5	0.5	GO:0021678	fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
0.5	2.5	GO:0055059	asymmetric neuroblast division(GO:0055059)
0.5	3.9	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.5	1.5	GO:0042823	pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.5	4.4	GO:2000344	positive regulation of acrosome reaction(GO:2000344)
0.5	1.5	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
0.5	1.9	GO:0060023	soft palate development(GO:0060023)
0.5	3.9	GO:0043570	maintenance of DNA repeat elements(GO:0043570)
0.5	4.8	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.5	1.4	GO:1904582	regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.5	1.9	GO:1904381	Golgi apparatus mannose trimming(GO:1904381)
0.5	3.8	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.5	8.1	GO:1900120	regulation of receptor binding(GO:1900120)
0.5	1.4	GO:0031017	exocrine pancreas development(GO:0031017)
0.5	4.2	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.5	4.2	GO:0001845	phagolysosome assembly(GO:0001845)
0.5	2.8	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.5	6.0	GO:0034501	protein localization to kinetochore(GO:0034501)
0.5	0.5	GO:2001302	lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.5	1.4	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.5	3.2	GO:1904352	positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.5	3.2	GO:0006489	dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
0.5	1.8	GO:0035750	protein localization to myelin sheath abaxonal region(GO:0035750)
0.5	1.8	GO:0060734	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.4	2.2	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.4	4.9	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.4	12.4	GO:0014850	response to muscle activity(GO:0014850)
0.4	3.5	GO:0042118	endothelial cell activation(GO:0042118)
0.4	0.4	GO:0097499	protein localization to nonmotile primary cilium(GO:0097499)
0.4	3.1	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.4	1.7	GO:0061188	regulation of chromatin silencing at rDNA(GO:0061187) negative regulation of chromatin silencing at rDNA(GO:0061188)
0.4	2.6	GO:0051549	positive regulation of keratinocyte migration(GO:0051549)
0.4	5.6	GO:0071468	cellular response to acidic pH(GO:0071468)
0.4	8.2	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.4	9.8	GO:0030325	adrenal gland development(GO:0030325)
0.4	5.1	GO:0001778	plasma membrane repair(GO:0001778)
0.4	5.0	GO:0042487	regulation of odontogenesis of dentin-containing tooth(GO:0042487)
0.4	1.3	GO:0010808	positive regulation of synaptic vesicle priming(GO:0010808)
0.4	2.1	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.4	7.1	GO:0097320	membrane tubulation(GO:0097320)
0.4	0.8	GO:0036100	leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
0.4	3.7	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.4	4.5	GO:0051639	actin filament network formation(GO:0051639)
0.4	10.2	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.4	4.1	GO:0097205	renal filtration(GO:0097205)
0.4	5.7	GO:0046325	negative regulation of glucose import(GO:0046325)
0.4	6.8	GO:0034356	NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.4	0.4	GO:0019336	phenol-containing compound catabolic process(GO:0019336)
0.4	0.8	GO:0048808	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.4	1.5	GO:0070460	thyroid-stimulating hormone secretion(GO:0070460) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.4	2.3	GO:0061298	retina vasculature development in camera-type eye(GO:0061298)
0.4	4.2	GO:0036445	forebrain neuroblast division(GO:0021873) neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057)
0.4	0.8	GO:0017055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.4	4.6	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.4	2.3	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.4	1.5	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.4	6.3	GO:0030497	fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.4	1.5	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.4	0.4	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.4	0.7	GO:0010825	positive regulation of centrosome duplication(GO:0010825)
0.4	4.0	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.4	0.4	GO:0072301	metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262) regulation of metanephric glomerular mesangial cell proliferation(GO:0072301)
0.4	1.5	GO:0018008	N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
0.4	1.5	GO:1902954	regulation of early endosome to recycling endosome transport(GO:1902954)
0.4	2.9	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.4	1.4	GO:0046946	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.4	3.2	GO:0097084	vascular smooth muscle cell development(GO:0097084)
0.4	2.1	GO:0032328	alanine transport(GO:0032328)
0.4	2.1	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.4	1.4	GO:0050917	sensory perception of umami taste(GO:0050917)
0.4	3.2	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.4	1.1	GO:0090341	negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.3	2.8	GO:0098535	de novo centriole assembly(GO:0098535)
0.3	1.0	GO:0045013	carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.3	5.9	GO:1903830	magnesium ion transmembrane transport(GO:1903830)
0.3	2.1	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.3	2.4	GO:0098722	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) asymmetric stem cell division(GO:0098722) germline stem cell asymmetric division(GO:0098728)
0.3	1.4	GO:0051462	cortisol secretion(GO:0043400) regulation of cortisol secretion(GO:0051462)
0.3	15.5	GO:0071377	cellular response to glucagon stimulus(GO:0071377)
0.3	1.7	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.3	0.3	GO:0061153	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.3	0.7	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.3	1.3	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.3	2.0	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.3	1.0	GO:0045906	negative regulation of vasoconstriction(GO:0045906)
0.3	2.3	GO:0035583	sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.3	4.9	GO:0039532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway(GO:0039532)
0.3	0.6	GO:1903691	positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.3	1.0	GO:0097021	lymphocyte migration into lymphoid organs(GO:0097021)
0.3	1.6	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.3	6.4	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.3	7.4	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.3	1.0	GO:1902269	positive regulation of polyamine transmembrane transport(GO:1902269)
0.3	1.3	GO:0015871	choline transport(GO:0015871)
0.3	1.3	GO:0071110	protein biotinylation(GO:0009305) histone biotinylation(GO:0071110)
0.3	4.1	GO:0006449	regulation of translational termination(GO:0006449)
0.3	3.5	GO:0042373	vitamin K metabolic process(GO:0042373)
0.3	2.2	GO:0001842	neural fold formation(GO:0001842)
0.3	1.3	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.3	0.6	GO:0002159	desmosome assembly(GO:0002159)
0.3	2.2	GO:2000647	negative regulation of stem cell proliferation(GO:2000647)
0.3	3.4	GO:0001977	renal system process involved in regulation of blood volume(GO:0001977)
0.3	3.4	GO:0048251	elastic fiber assembly(GO:0048251)
0.3	3.1	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.3	1.5	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.3	1.2	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.3	2.7	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.3	1.5	GO:0046167	glycerol-3-phosphate biosynthetic process(GO:0046167)
0.3	0.6	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.3	0.9	GO:0045586	regulation of gamma-delta T cell differentiation(GO:0045586)
0.3	0.6	GO:0003174	mitral valve development(GO:0003174)
0.3	1.8	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.3	2.4	GO:0010998	regulation of translational initiation by eIF2 alpha phosphorylation(GO:0010998)
0.3	0.9	GO:0021763	subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.3	1.2	GO:0002501	peptide antigen assembly with MHC protein complex(GO:0002501)
0.3	5.9	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.3	2.3	GO:0048262	determination of dorsal/ventral asymmetry(GO:0048262)
0.3	2.0	GO:0010669	epithelial structure maintenance(GO:0010669)
0.3	4.1	GO:0016024	CDP-diacylglycerol biosynthetic process(GO:0016024)
0.3	1.4	GO:1903936	cellular response to sodium arsenite(GO:1903936)
0.3	0.6	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
0.3	2.3	GO:0055129	proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.3	1.7	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.3	1.1	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.3	2.5	GO:0071492	cellular response to UV-A(GO:0071492)
0.3	2.2	GO:0008298	intracellular mRNA localization(GO:0008298)
0.3	0.6	GO:2000325	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.3	2.0	GO:0035879	plasma membrane lactate transport(GO:0035879)
0.3	0.8	GO:0072008	mesangial cell differentiation(GO:0072007) glomerular mesangial cell differentiation(GO:0072008) kidney interstitial fibroblast differentiation(GO:0072071) renal interstitial fibroblast development(GO:0072141) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) pericyte cell differentiation(GO:1904238)
0.3	0.6	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.3	2.0	GO:0006662	glycerol ether metabolic process(GO:0006662)
0.3	0.8	GO:0005989	lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.3	5.0	GO:0071711	basement membrane organization(GO:0071711)
0.3	6.3	GO:0035635	entry of bacterium into host cell(GO:0035635)
0.3	1.1	GO:0019074	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.3	1.7	GO:0061767	negative regulation of lung blood pressure(GO:0061767)
0.3	1.1	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
0.3	5.5	GO:0046320	regulation of fatty acid oxidation(GO:0046320)
0.3	2.5	GO:0000050	urea cycle(GO:0000050)
0.3	20.2	GO:1901016	regulation of potassium ion transmembrane transporter activity(GO:1901016)
0.3	1.1	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
0.3	4.9	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.3	1.3	GO:0033133	positive regulation of glucokinase activity(GO:0033133)
0.3	1.6	GO:0006983	ER overload response(GO:0006983)
0.3	7.0	GO:2000811	negative regulation of anoikis(GO:2000811)
0.3	0.5	GO:2000586	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586)
0.3	5.1	GO:0022011	myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.3	1.6	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
0.3	2.9	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.3	4.0	GO:0071577	zinc II ion transmembrane transport(GO:0071577)
0.3	1.1	GO:0032916	transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910) positive regulation of transforming growth factor beta3 production(GO:0032916)
0.3	0.8	GO:0048733	sebaceous gland development(GO:0048733)
0.3	1.1	GO:0051944	positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.3	2.1	GO:0035087	siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.3	1.8	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.3	0.8	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
0.3	1.3	GO:0006127	glycerophosphate shuttle(GO:0006127)
0.3	0.5	GO:2000170	regulation of renal output by angiotensin(GO:0002019) positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.3	2.3	GO:0070508	sterol import(GO:0035376) cholesterol import(GO:0070508)
0.3	0.5	GO:2000195	negative regulation of female gonad development(GO:2000195)
0.3	0.8	GO:0051684	maintenance of Golgi location(GO:0051684)
0.3	0.8	GO:0098582	innate vocalization behavior(GO:0098582)
0.2	0.5	GO:0070662	mast cell proliferation(GO:0070662)
0.2	0.2	GO:0001554	luteolysis(GO:0001554)
0.2	7.8	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.2	1.0	GO:1904783	negative regulation of glutamate receptor signaling pathway(GO:1900450) negative regulation of NMDA glutamate receptor activity(GO:1904782) positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.2	11.3	GO:0043297	apical junction assembly(GO:0043297)
0.2	1.4	GO:2000158	positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.2	1.4	GO:0097396	response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.2	0.7	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.2	0.7	GO:0046452	dihydrofolate metabolic process(GO:0046452)
0.2	0.9	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
0.2	0.5	GO:0046533	negative regulation of photoreceptor cell differentiation(GO:0046533)
0.2	8.9	GO:0006896	Golgi to vacuole transport(GO:0006896)
0.2	0.2	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
0.2	0.2	GO:0060364	frontal suture morphogenesis(GO:0060364)
0.2	2.3	GO:0034315	regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.2	0.9	GO:0060282	positive regulation of oocyte development(GO:0060282)
0.2	3.3	GO:0006828	manganese ion transport(GO:0006828)
0.2	2.0	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.2	2.9	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.2	0.4	GO:0035822	gene conversion(GO:0035822)
0.2	0.7	GO:0042369	vitamin D catabolic process(GO:0042369)
0.2	0.7	GO:0048691	modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.2	4.3	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.2	0.7	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2	0.6	GO:0002184	cytoplasmic translational termination(GO:0002184)
0.2	1.3	GO:0014054	positive regulation of gamma-aminobutyric acid secretion(GO:0014054)
0.2	1.3	GO:0016926	protein desumoylation(GO:0016926)
0.2	1.9	GO:0030807	positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822)
0.2	0.6	GO:0030920	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.2	0.6	GO:0032815	negative regulation of natural killer cell activation(GO:0032815)
0.2	1.7	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.2	2.5	GO:0034380	high-density lipoprotein particle assembly(GO:0034380)
0.2	0.6	GO:2000317	negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.2	1.0	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.2	1.0	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.2	0.4	GO:0035691	macrophage migration inhibitory factor signaling pathway(GO:0035691)
0.2	5.5	GO:0035329	hippo signaling(GO:0035329)
0.2	2.9	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.2	3.7	GO:0033622	integrin activation(GO:0033622)
0.2	0.2	GO:0090521	glomerular visceral epithelial cell migration(GO:0090521)
0.2	1.4	GO:0051084	'de novo' posttranslational protein folding(GO:0051084)
0.2	1.2	GO:0006710	androgen catabolic process(GO:0006710)
0.2	2.0	GO:0030322	stabilization of membrane potential(GO:0030322)
0.2	5.4	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.2	9.9	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.2	18.5	GO:0042035	regulation of cytokine biosynthetic process(GO:0042035)
0.2	3.3	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2	3.5	GO:0048009	insulin-like growth factor receptor signaling pathway(GO:0048009)
0.2	0.6	GO:0043415	myoblast fate determination(GO:0007518) positive regulation of skeletal muscle tissue regeneration(GO:0043415) regulation of skeletal muscle tissue regeneration(GO:0043416)
0.2	1.0	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.2	0.2	GO:0048631	regulation of skeletal muscle tissue growth(GO:0048631)
0.2	0.8	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.2	2.4	GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.2	2.8	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.2	3.4	GO:0045109	intermediate filament organization(GO:0045109)
0.2	2.2	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.2	0.7	GO:1903803	glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
0.2	4.1	GO:2000352	negative regulation of endothelial cell apoptotic process(GO:2000352)
0.2	0.2	GO:0031269	cell motility involved in cerebral cortex radial glia guided migration(GO:0021814) modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815) pseudopodium assembly(GO:0031269)
0.2	1.7	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.2	1.8	GO:0034138	toll-like receptor 3 signaling pathway(GO:0034138)
0.2	2.0	GO:0043249	erythrocyte maturation(GO:0043249)
0.2	1.7	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2	5.1	GO:0007080	mitotic metaphase plate congression(GO:0007080)
0.2	0.4	GO:1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance(GO:1902285)
0.2	0.4	GO:0042481	regulation of odontogenesis(GO:0042481)
0.2	1.3	GO:0015705	iodide transport(GO:0015705)
0.2	0.2	GO:0030540	female genitalia development(GO:0030540)
0.2	1.8	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
0.2	1.1	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.2	0.5	GO:0043435	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.2	0.9	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
0.2	1.8	GO:1904896	ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.2	1.1	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.2	0.9	GO:0035973	aggrephagy(GO:0035973)
0.2	0.7	GO:0035413	positive regulation of catenin import into nucleus(GO:0035413)
0.2	0.2	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.2	2.8	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.2	6.0	GO:0002011	morphogenesis of an epithelial sheet(GO:0002011)
0.2	1.2	GO:0034587	piRNA metabolic process(GO:0034587)
0.2	1.2	GO:0046541	saliva secretion(GO:0046541)
0.2	1.5	GO:0032330	regulation of chondrocyte differentiation(GO:0032330)
0.2	7.1	GO:0071470	cellular response to osmotic stress(GO:0071470)
0.2	0.2	GO:0038163	thrombopoietin-mediated signaling pathway(GO:0038163)
0.2	4.1	GO:0030488	tRNA methylation(GO:0030488)
0.2	0.3	GO:0035854	regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854) regulation of forebrain neuron differentiation(GO:2000977)
0.2	5.7	GO:0043277	apoptotic cell clearance(GO:0043277)
0.2	1.8	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
0.2	4.2	GO:0060384	innervation(GO:0060384)
0.2	1.3	GO:0036500	ATF6-mediated unfolded protein response(GO:0036500)
0.2	0.8	GO:0016198	axon choice point recognition(GO:0016198)
0.2	1.0	GO:0048266	behavioral response to pain(GO:0048266)
0.2	0.7	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.2	2.2	GO:0033617	mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.2	0.5	GO:0051127	positive regulation of actin nucleation(GO:0051127)
0.2	0.3	GO:1900114	positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.2	2.0	GO:0046085	adenosine metabolic process(GO:0046085)
0.2	1.3	GO:0032793	positive regulation of CREB transcription factor activity(GO:0032793)
0.2	1.5	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.2	1.0	GO:0042713	sperm ejaculation(GO:0042713)
0.2	2.0	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.2	2.1	GO:0015732	prostaglandin transport(GO:0015732)
0.2	0.8	GO:0060081	membrane hyperpolarization(GO:0060081)
0.2	1.8	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.2	1.1	GO:0046755	viral budding(GO:0046755) multi-organism organelle organization(GO:1902590) multi-organism membrane budding(GO:1902592)
0.2	5.4	GO:0001706	endoderm formation(GO:0001706)
0.2	0.3	GO:0097211	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2	1.3	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.2	0.6	GO:0033197	response to vitamin E(GO:0033197)
0.2	2.2	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.2	0.8	GO:2000467	positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.2	1.6	GO:1900112	regulation of histone H3-K9 trimethylation(GO:1900112)
0.2	0.3	GO:0021986	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.2	2.3	GO:0030199	collagen fibril organization(GO:0030199)
0.2	2.0	GO:0003091	renal water homeostasis(GO:0003091)
0.2	0.3	GO:0021800	cerebral cortex tangential migration(GO:0021800)
0.2	0.5	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.2	0.9	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.1	1.0	GO:0045023	G0 to G1 transition(GO:0045023)
0.1	1.8	GO:0001569	patterning of blood vessels(GO:0001569)
0.1	1.5	GO:0045717	negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1	1.8	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.1	8.3	GO:0016266	O-glycan processing(GO:0016266)
0.1	1.3	GO:2000576	positive regulation of microtubule motor activity(GO:2000576)
0.1	0.1	GO:0003415	chondrocyte hypertrophy(GO:0003415)
0.1	0.6	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.1	1.0	GO:0070255	regulation of mucus secretion(GO:0070255) positive regulation of mucus secretion(GO:0070257)
0.1	1.4	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.1	1.4	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.1	0.6	GO:0099558	maintenance of synapse structure(GO:0099558)
0.1	2.9	GO:0045746	negative regulation of Notch signaling pathway(GO:0045746)
0.1	1.5	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.8	GO:0002353	kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
0.1	0.7	GO:0030916	otic vesicle formation(GO:0030916)
0.1	0.3	GO:1902358	sulfate transmembrane transport(GO:1902358)
0.1	3.9	GO:0006783	heme biosynthetic process(GO:0006783)
0.1	3.8	GO:0051017	actin filament bundle assembly(GO:0051017)
0.1	1.2	GO:0046940	nucleoside monophosphate phosphorylation(GO:0046940)
0.1	0.3	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.1	2.8	GO:0048665	neuron fate specification(GO:0048665)
0.1	0.9	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1	2.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.1	3.2	GO:0051292	nuclear pore complex assembly(GO:0051292)
0.1	1.3	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.1	1.8	GO:0021957	corticospinal tract morphogenesis(GO:0021957)
0.1	0.7	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.1	0.7	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1	0.7	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.1	0.9	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.1	3.4	GO:0006465	signal peptide processing(GO:0006465)
0.1	2.5	GO:0071425	hematopoietic stem cell proliferation(GO:0071425)
0.1	0.3	GO:1905064	negative regulation of vascular smooth muscle cell differentiation(GO:1905064)
0.1	0.4	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.1	1.0	GO:0070475	rRNA base methylation(GO:0070475)
0.1	0.4	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.1	0.6	GO:1900452	regulation of long term synaptic depression(GO:1900452)
0.1	1.1	GO:0071926	endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.1	1.9	GO:0007141	male meiosis I(GO:0007141)
0.1	0.6	GO:0045872	positive regulation of rhodopsin gene expression(GO:0045872)
0.1	0.4	GO:0014745	negative regulation of muscle adaptation(GO:0014745)
0.1	0.5	GO:0006238	CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1	1.1	GO:0061339	establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.1	1.5	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.1	0.9	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.9	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1	0.1	GO:0032353	negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of hormone biosynthetic process(GO:0032353) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.1	3.0	GO:0030252	growth hormone secretion(GO:0030252)
0.1	3.2	GO:1904659	hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.1	1.7	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.1	1.2	GO:0032025	response to cobalt ion(GO:0032025)
0.1	0.8	GO:0060056	mammary gland involution(GO:0060056)
0.1	0.5	GO:0048149	behavioral response to ethanol(GO:0048149)
0.1	0.8	GO:0001825	blastocyst formation(GO:0001825)
0.1	0.5	GO:0035754	B cell chemotaxis(GO:0035754)
0.1	4.6	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.1	4.8	GO:0010761	fibroblast migration(GO:0010761)
0.1	1.1	GO:0072520	seminiferous tubule development(GO:0072520)
0.1	8.5	GO:0001523	retinoid metabolic process(GO:0001523)
0.1	1.4	GO:2000505	regulation of energy homeostasis(GO:2000505)
0.1	0.7	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1	0.7	GO:0048485	sympathetic nervous system development(GO:0048485)
0.1	6.3	GO:0030282	bone mineralization(GO:0030282)
0.1	0.3	GO:0098974	postsynaptic actin cytoskeleton organization(GO:0098974)
0.1	0.4	GO:0090301	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1	4.8	GO:0030574	collagen catabolic process(GO:0030574)
0.1	0.6	GO:0046092	deoxycytidine metabolic process(GO:0046092)
0.1	0.6	GO:0072719	cellular response to cisplatin(GO:0072719)
0.1	0.5	GO:0038042	dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1	1.3	GO:0010811	positive regulation of cell-substrate adhesion(GO:0010811)
0.1	0.2	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
0.1	0.4	GO:0048730	epidermis morphogenesis(GO:0048730)
0.1	0.7	GO:0021846	cell proliferation in forebrain(GO:0021846)
0.1	0.3	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading(GO:1900025)
0.1	0.6	GO:0006907	pinocytosis(GO:0006907)
0.1	0.5	GO:0071455	cellular response to hyperoxia(GO:0071455)
0.1	3.4	GO:0034446	substrate adhesion-dependent cell spreading(GO:0034446)
0.1	1.0	GO:0002227	innate immune response in mucosa(GO:0002227)
0.1	0.3	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.1	0.4	GO:0001880	Mullerian duct regression(GO:0001880)
0.1	1.1	GO:0035246	peptidyl-arginine N-methylation(GO:0035246)
0.1	5.4	GO:0015701	bicarbonate transport(GO:0015701)
0.1	2.7	GO:0045214	sarcomere organization(GO:0045214)
0.1	0.2	GO:0030035	microspike assembly(GO:0030035)
0.1	0.3	GO:1901804	beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
0.1	3.6	GO:0000027	ribosomal large subunit assembly(GO:0000027)
0.1	0.1	GO:1900756	protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.1	0.6	GO:0048711	positive regulation of astrocyte differentiation(GO:0048711)
0.1	2.8	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.1	0.3	GO:0090009	primitive streak formation(GO:0090009)
0.1	1.3	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.1	1.0	GO:0015812	gamma-aminobutyric acid transport(GO:0015812)
0.1	0.7	GO:0051775	response to redox state(GO:0051775)
0.1	0.3	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1	0.5	GO:0071027	nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.1	1.4	GO:2000179	positive regulation of neural precursor cell proliferation(GO:2000179)
0.1	0.2	GO:0071623	negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.1	6.3	GO:0007229	integrin-mediated signaling pathway(GO:0007229)
0.1	0.3	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.1	2.7	GO:0045600	positive regulation of fat cell differentiation(GO:0045600)
0.1	0.6	GO:1902741	type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.1	1.4	GO:0003310	pancreatic A cell differentiation(GO:0003310)
0.1	0.8	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.1	0.3	GO:0098703	calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1	1.0	GO:1903441	protein localization to ciliary membrane(GO:1903441)
0.1	1.5	GO:0032098	regulation of appetite(GO:0032098)
0.1	1.2	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1	0.4	GO:0014820	tonic smooth muscle contraction(GO:0014820) artery smooth muscle contraction(GO:0014824)
0.1	0.9	GO:0048535	lymph node development(GO:0048535)
0.1	1.5	GO:0046069	cGMP catabolic process(GO:0046069)
0.1	0.5	GO:0003096	renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.1	0.8	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1	2.0	GO:0006622	protein targeting to lysosome(GO:0006622)
0.1	2.0	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.1	1.2	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1	0.5	GO:0045054	constitutive secretory pathway(GO:0045054) regulation of constitutive secretory pathway(GO:1903433)
0.1	2.6	GO:0030888	regulation of B cell proliferation(GO:0030888)
0.1	0.8	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.1	0.2	GO:0071529	cementum mineralization(GO:0071529)
0.1	0.5	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1	0.1	GO:0060033	anatomical structure regression(GO:0060033)
0.1	0.5	GO:0042797	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1	1.8	GO:0009303	rRNA transcription(GO:0009303)
0.1	4.4	GO:0007218	neuropeptide signaling pathway(GO:0007218)
0.1	0.3	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.1	0.9	GO:0006600	creatine metabolic process(GO:0006600)
0.1	0.1	GO:1900084	regulation of peptidyl-tyrosine autophosphorylation(GO:1900084)
0.1	1.6	GO:1901185	negative regulation of ERBB signaling pathway(GO:1901185)
0.1	0.5	GO:0002566	somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1	0.3	GO:1903012	positive regulation of bone development(GO:1903012) positive regulation of osteoclast development(GO:2001206)
0.1	1.9	GO:0032755	positive regulation of interleukin-6 production(GO:0032755)
0.1	1.2	GO:0009880	embryonic pattern specification(GO:0009880)
0.1	1.2	GO:0000289	nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.1	0.5	GO:0060736	prostate gland growth(GO:0060736)
0.1	1.1	GO:0045589	regulation of regulatory T cell differentiation(GO:0045589)
0.1	0.4	GO:0007530	sex determination(GO:0007530)
0.1	0.2	GO:0060087	relaxation of smooth muscle(GO:0044557) relaxation of vascular smooth muscle(GO:0060087)
0.1	0.5	GO:0040020	regulation of meiotic nuclear division(GO:0040020)
0.1	0.2	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.1	6.7	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1	3.8	GO:0030330	DNA damage response, signal transduction by p53 class mediator(GO:0030330)
0.1	2.3	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.1	0.5	GO:0031442	positive regulation of mRNA 3'-end processing(GO:0031442)
0.1	2.5	GO:0051965	positive regulation of synapse assembly(GO:0051965)
0.1	0.8	GO:0003334	keratinocyte development(GO:0003334)
0.1	2.0	GO:0060395	SMAD protein signal transduction(GO:0060395)
0.0	0.3	GO:0042255	ribosome assembly(GO:0042255)
0.0	0.7	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.2	GO:0046125	thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0	0.1	GO:0071233	cellular response to leucine(GO:0071233)
0.0	0.4	GO:0032875	regulation of DNA endoreduplication(GO:0032875) DNA endoreduplication(GO:0042023)
0.0	0.3	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:0051445	regulation of meiotic cell cycle(GO:0051445)
0.0	0.8	GO:1901663	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.5	GO:0001755	neural crest cell migration(GO:0001755)
0.0	0.8	GO:0006359	regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0	0.6	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.1	GO:2001028	positive regulation of endothelial cell chemotaxis(GO:2001028)
0.0	0.2	GO:0042748	circadian sleep/wake cycle, non-REM sleep(GO:0042748) regulation of circadian sleep/wake cycle, non-REM sleep(GO:0045188)
0.0	0.2	GO:0023021	termination of signal transduction(GO:0023021)
0.0	0.5	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.3	GO:0007379	segment specification(GO:0007379)
0.0	1.0	GO:0030224	monocyte differentiation(GO:0030224)
0.0	0.4	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.0	0.9	GO:0050912	detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.0	0.5	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.0	1.3	GO:0019228	neuronal action potential(GO:0019228)
0.0	0.0	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.0	GO:0021562	vestibulocochlear nerve development(GO:0021562)
0.0	0.6	GO:0000042	protein targeting to Golgi(GO:0000042)
0.0	0.2	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.4	GO:0030828	positive regulation of cGMP biosynthetic process(GO:0030828)
0.0	0.1	GO:0002903	negative regulation of B cell apoptotic process(GO:0002903)
0.0	0.5	GO:0098779	mitophagy in response to mitochondrial depolarization(GO:0098779)
0.0	0.6	GO:0006482	protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0	0.2	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.0	0.3	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383)
0.0	0.5	GO:0090083	regulation of inclusion body assembly(GO:0090083)
0.0	0.4	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.0	0.5	GO:0044458	motile cilium assembly(GO:0044458)
0.0	0.9	GO:0000281	mitotic cytokinesis(GO:0000281)
0.0	0.7	GO:0051482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0	0.2	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0	4.5	GO:0006665	sphingolipid metabolic process(GO:0006665)
0.0	0.5	GO:0050891	multicellular organismal water homeostasis(GO:0050891)
0.0	0.4	GO:0034067	protein localization to Golgi apparatus(GO:0034067)
0.0	0.2	GO:0045671	negative regulation of osteoclast differentiation(GO:0045671)
0.0	0.8	GO:1903959	regulation of anion transmembrane transport(GO:1903959)
0.0	0.7	GO:0072488	ammonium transmembrane transport(GO:0072488)
0.0	0.2	GO:0032218	riboflavin transport(GO:0032218)
0.0	0.3	GO:0035589	G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0	0.3	GO:0030728	ovulation(GO:0030728)
0.0	0.8	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.5	GO:0001657	ureteric bud development(GO:0001657) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.0	0.1	GO:0038203	TORC2 signaling(GO:0038203)
0.0	1.9	GO:0007160	cell-matrix adhesion(GO:0007160)
0.0	0.5	GO:0007043	cell-cell junction assembly(GO:0007043)
0.0	0.5	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.0	0.0	GO:0060687	regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.0	0.3	GO:0009798	axis specification(GO:0009798)
0.0	0.0	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0	1.4	GO:0048207	vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	2.6	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.9	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.1	GO:0072176	nephric duct development(GO:0072176)
0.0	0.2	GO:1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.2	GO:0032354	response to follicle-stimulating hormone(GO:0032354)
0.0	0.2	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	1.7	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.1	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	1.9	GO:0031032	actomyosin structure organization(GO:0031032)
0.0	0.2	GO:0098914	membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0	0.1	GO:0015671	oxygen transport(GO:0015671)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.2	GO:0071320	cellular response to cAMP(GO:0071320)
0.0	0.3	GO:0046597	negative regulation of viral entry into host cell(GO:0046597)
0.0	0.1	GO:0060008	Sertoli cell differentiation(GO:0060008)
0.0	0.4	GO:0033275	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
3.2	12.8	GO:0070435	Shc-EGFR complex(GO:0070435)
3.1	24.7	GO:0005587	collagen type IV trimer(GO:0005587)
3.0	11.8	GO:0034667	integrin alpha3-beta1 complex(GO:0034667)
2.9	8.6	GO:1902737	dendritic filopodium(GO:1902737)
2.7	27.0	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
2.4	16.8	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
2.3	6.8	GO:0043259	laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
2.2	37.4	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
2.0	6.1	GO:0034686	integrin alphav-beta8 complex(GO:0034686)
1.9	25.2	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
1.8	7.1	GO:0048179	activin receptor complex(GO:0048179)
1.7	14.9	GO:0071953	elastic fiber(GO:0071953)
1.5	31.6	GO:0044300	cerebellar mossy fiber(GO:0044300)
1.5	4.4	GO:0034455	t-UTP complex(GO:0034455)
1.4	11.1	GO:0061689	tricellular tight junction(GO:0061689)
1.3	18.3	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
1.3	6.5	GO:0070847	core mediator complex(GO:0070847)
1.3	5.0	GO:0000818	nuclear MIS12/MIND complex(GO:0000818)
1.2	17.0	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
1.1	11.5	GO:0016011	dystroglycan complex(GO:0016011)
1.1	14.2	GO:0005915	zonula adherens(GO:0005915)
1.1	17.2	GO:0097470	ribbon synapse(GO:0097470)
1.0	11.5	GO:0005577	fibrinogen complex(GO:0005577)
1.0	3.1	GO:0032426	stereocilium tip(GO:0032426)
1.0	2.0	GO:0005899	insulin receptor complex(GO:0005899)
1.0	3.0	GO:0043512	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
1.0	4.9	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
1.0	6.9	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
1.0	6.7	GO:0071664	beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.9	3.7	GO:0071942	XPC complex(GO:0071942)
0.9	4.5	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.9	2.7	GO:0097135	cyclin E2-CDK2 complex(GO:0097135)
0.8	1.7	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.8	0.8	GO:0034681	integrin alpha11-beta1 complex(GO:0034681)
0.8	4.2	GO:0016589	NURF complex(GO:0016589)
0.8	30.6	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.8	4.8	GO:0031501	mannosyltransferase complex(GO:0031501)
0.8	4.0	GO:0031673	H zone(GO:0031673)
0.8	2.4	GO:0071148	TEAD-1-YAP complex(GO:0071148)
0.8	2.3	GO:0098536	deuterosome(GO:0098536)
0.8	6.8	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.7	6.6	GO:0000938	GARP complex(GO:0000938)
0.7	5.8	GO:0033655	host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.7	22.3	GO:0005921	gap junction(GO:0005921)
0.7	16.2	GO:0005916	fascia adherens(GO:0005916)
0.7	4.1	GO:0034751	aryl hydrocarbon receptor complex(GO:0034751)
0.7	10.7	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.6	11.0	GO:0030056	hemidesmosome(GO:0030056)
0.6	6.9	GO:0005638	lamin filament(GO:0005638)
0.6	3.0	GO:0071458	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458)
0.6	3.0	GO:0032302	MutSbeta complex(GO:0032302)
0.6	1.2	GO:0071546	pi-body(GO:0071546)
0.6	1.8	GO:0070939	Dsl1p complex(GO:0070939)
0.6	13.8	GO:0002080	acrosomal membrane(GO:0002080)
0.6	4.0	GO:0030991	intraciliary transport particle A(GO:0030991)
0.6	7.4	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.6	1.7	GO:0097123	cyclin A1-CDK2 complex(GO:0097123)
0.6	2.2	GO:0005960	glycine cleavage complex(GO:0005960)
0.6	0.6	GO:0097059	CNTFR-CLCF1 complex(GO:0097059)
0.5	17.9	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.5	3.2	GO:0005610	laminin-5 complex(GO:0005610)
0.5	1.6	GO:0005600	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.5	3.2	GO:0014802	terminal cisterna(GO:0014802)
0.5	1.6	GO:0070701	mucus layer(GO:0070701)
0.5	5.2	GO:0031941	filamentous actin(GO:0031941)
0.5	9.3	GO:0030014	CCR4-NOT complex(GO:0030014)
0.5	4.4	GO:0033391	chromatoid body(GO:0033391)
0.5	1.4	GO:0044609	DBIRD complex(GO:0044609)
0.5	0.9	GO:0060201	clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.5	2.8	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.5	7.3	GO:0035102	PRC1 complex(GO:0035102)
0.5	4.1	GO:0072546	ER membrane protein complex(GO:0072546)
0.4	4.0	GO:0005787	signal peptidase complex(GO:0005787)
0.4	6.0	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.4	2.5	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.4	43.5	GO:0005796	Golgi lumen(GO:0005796)
0.4	1.1	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.4	3.7	GO:0051286	cell tip(GO:0051286)
0.4	35.9	GO:0032432	actin filament bundle(GO:0032432)
0.4	1.1	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.4	1.8	GO:1990761	growth cone lamellipodium(GO:1990761)
0.4	1.1	GO:0031515	tRNA (m1A) methyltransferase complex(GO:0031515)
0.3	2.1	GO:0033061	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.3	6.8	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.3	2.0	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.3	3.7	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.3	6.7	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.3	4.0	GO:0030126	COPI vesicle coat(GO:0030126)
0.3	3.3	GO:0097443	sorting endosome(GO:0097443)
0.3	2.6	GO:0005845	mRNA cap binding complex(GO:0005845)
0.3	1.0	GO:0031262	Ndc80 complex(GO:0031262)
0.3	1.6	GO:0031905	early endosome lumen(GO:0031905)
0.3	4.0	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3	0.9	GO:0033593	BRCA2-MAGE-D1 complex(GO:0033593)
0.3	2.2	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.3	5.7	GO:0031089	platelet dense granule lumen(GO:0031089)
0.3	0.9	GO:0032301	MutSalpha complex(GO:0032301)
0.3	4.2	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.3	6.7	GO:0030057	desmosome(GO:0030057)
0.3	0.6	GO:1990425	ryanodine receptor complex(GO:1990425)
0.3	2.5	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.3	1.7	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
0.3	2.4	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.3	2.4	GO:0032133	chromosome passenger complex(GO:0032133)
0.3	0.5	GO:0044305	calyx of Held(GO:0044305)
0.3	1.1	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
0.3	1.8	GO:0036021	endolysosome lumen(GO:0036021)
0.3	0.5	GO:0016342	catenin complex(GO:0016342)
0.2	1.0	GO:0044307	dendritic branch(GO:0044307)
0.2	2.4	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2	8.6	GO:0000421	autophagosome membrane(GO:0000421)
0.2	7.6	GO:0032809	neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.2	4.0	GO:0008091	spectrin(GO:0008091)
0.2	3.2	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2	4.4	GO:0036038	MKS complex(GO:0036038)
0.2	1.8	GO:0043219	lateral loop(GO:0043219)
0.2	1.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.2	4.7	GO:0044447	axoneme part(GO:0044447)
0.2	1.3	GO:0005816	spindle pole body(GO:0005816)
0.2	1.3	GO:0001940	male pronucleus(GO:0001940)
0.2	9.8	GO:0043034	costamere(GO:0043034)
0.2	1.1	GO:0005713	recombination nodule(GO:0005713)
0.2	1.3	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.2	19.4	GO:0005913	cell-cell adherens junction(GO:0005913)
0.2	1.3	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2	0.6	GO:0018444	translation release factor complex(GO:0018444)
0.2	6.0	GO:0034361	very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.2	0.9	GO:0070876	SOSS complex(GO:0070876)
0.2	2.3	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.2	1.2	GO:0072687	meiotic spindle(GO:0072687)
0.2	1.4	GO:0097165	nuclear stress granule(GO:0097165)
0.2	4.0	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.2	1.2	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.2	1.1	GO:0071797	LUBAC complex(GO:0071797)
0.2	1.1	GO:0033269	internode region of axon(GO:0033269)
0.2	2.0	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2	5.8	GO:1902711	GABA-A receptor complex(GO:1902711)
0.2	9.8	GO:0005581	collagen trimer(GO:0005581)
0.2	11.7	GO:0005902	microvillus(GO:0005902)
0.2	22.3	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.2	3.3	GO:0032590	dendrite membrane(GO:0032590)
0.2	0.8	GO:0070826	paraferritin complex(GO:0070826)
0.2	2.5	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.2	1.8	GO:0099738	cell cortex region(GO:0099738)
0.2	1.8	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2	1.6	GO:0060293	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.2	0.9	GO:0033553	rDNA heterochromatin(GO:0033553)
0.2	0.5	GO:0031933	telomeric heterochromatin(GO:0031933)
0.2	0.5	GO:0097224	sperm connecting piece(GO:0097224)
0.2	2.0	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2	0.6	GO:0002945	cyclin K-CDK13 complex(GO:0002945)
0.2	0.8	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.1	2.5	GO:0035869	ciliary transition zone(GO:0035869)
0.1	2.1	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.1	0.4	GO:0030906	retromer, cargo-selective complex(GO:0030906)
0.1	18.2	GO:0043296	apical junction complex(GO:0043296)
0.1	1.3	GO:0005652	nuclear lamina(GO:0005652)
0.1	2.9	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.1	1.7	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.1	36.5	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.1	0.9	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	1.0	GO:0044294	dendritic growth cone(GO:0044294)
0.1	0.5	GO:0030893	meiotic cohesin complex(GO:0030893)
0.1	1.2	GO:0071141	SMAD protein complex(GO:0071141)
0.1	0.6	GO:0032280	symmetric synapse(GO:0032280)
0.1	1.3	GO:0044666	MLL3/4 complex(GO:0044666)
0.1	5.9	GO:0031526	brush border membrane(GO:0031526)
0.1	0.5	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.1	1.7	GO:0031616	spindle pole centrosome(GO:0031616)
0.1	1.6	GO:0031095	platelet dense tubular network membrane(GO:0031095)
0.1	2.0	GO:0031045	dense core granule(GO:0031045)
0.1	9.0	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	0.6	GO:0097524	sperm plasma membrane(GO:0097524)
0.1	1.6	GO:0030478	actin cap(GO:0030478)
0.1	0.7	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.1	2.4	GO:0034451	centriolar satellite(GO:0034451)
0.1	1.0	GO:0045180	basal cortex(GO:0045180)
0.1	0.4	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.1	0.4	GO:0030914	STAGA complex(GO:0030914)
0.1	6.4	GO:0055038	recycling endosome membrane(GO:0055038)
0.1	0.5	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.1	0.5	GO:0089701	U2AF(GO:0089701)
0.1	1.5	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.1	0.4	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
0.1	0.6	GO:0097208	alveolar lamellar body(GO:0097208)
0.1	0.3	GO:0035189	Rb-E2F complex(GO:0035189)
0.1	8.2	GO:0005901	caveola(GO:0005901)
0.1	1.1	GO:0031209	SCAR complex(GO:0031209)
0.1	0.3	GO:0070695	FHF complex(GO:0070695)
0.1	3.7	GO:0034707	chloride channel complex(GO:0034707)
0.1	0.9	GO:0010369	chromocenter(GO:0010369)
0.1	0.5	GO:0043083	synaptic cleft(GO:0043083)
0.1	0.3	GO:0016939	kinesin II complex(GO:0016939)
0.1	0.8	GO:0000145	exocyst(GO:0000145)
0.1	0.8	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.1	2.4	GO:0008305	integrin complex(GO:0008305)
0.1	2.7	GO:0032154	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1	0.9	GO:0070449	elongin complex(GO:0070449)
0.1	5.0	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.1	0.8	GO:0000800	lateral element(GO:0000800)
0.1	1.7	GO:0001891	phagocytic cup(GO:0001891)
0.1	0.3	GO:0042584	chromaffin granule membrane(GO:0042584)
0.1	1.3	GO:0051233	spindle midzone(GO:0051233)
0.1	3.6	GO:0005844	polysome(GO:0005844)
0.1	7.9	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.1	1.5	GO:0034706	sodium channel complex(GO:0034706)
0.1	0.6	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.1	0.9	GO:0097225	sperm midpiece(GO:0097225)
0.1	0.8	GO:0097431	mitotic spindle pole(GO:0097431)
0.1	0.5	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.1	7.1	GO:0005814	centriole(GO:0005814)
0.1	0.2	GO:0044611	nuclear pore inner ring(GO:0044611)
0.1	1.7	GO:0002102	podosome(GO:0002102)
0.1	3.0	GO:0030315	T-tubule(GO:0030315)
0.1	0.9	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	1.4	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
0.1	0.5	GO:1903440	calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1	0.4	GO:0060091	kinocilium(GO:0060091)
0.1	0.4	GO:0070554	synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1	0.5	GO:0035253	ciliary rootlet(GO:0035253)
0.1	0.4	GO:0031415	N-terminal protein acetyltransferase complex(GO:0031414) NatA complex(GO:0031415)
0.1	0.2	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.1	0.5	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.1	1.2	GO:0097546	ciliary base(GO:0097546)
0.1	1.3	GO:0031201	SNARE complex(GO:0031201)
0.1	4.0	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	1.6	GO:0005892	acetylcholine-gated channel complex(GO:0005892)
0.1	22.5	GO:0005925	focal adhesion(GO:0005925)
0.1	1.0	GO:0032839	dendrite cytoplasm(GO:0032839)
0.1	5.8	GO:0017053	transcriptional repressor complex(GO:0017053)
0.1	0.5	GO:0000780	condensed nuclear chromosome, centromeric region(GO:0000780)
0.1	3.3	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.1	1.4	GO:0035145	exon-exon junction complex(GO:0035145)
0.1	0.2	GO:0005965	protein farnesyltransferase complex(GO:0005965)
0.1	1.0	GO:0034704	calcium channel complex(GO:0034704)
0.0	8.5	GO:0044798	nuclear transcription factor complex(GO:0044798)
0.0	0.7	GO:0031312	extrinsic component of organelle membrane(GO:0031312)
0.0	0.3	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	1.2	GO:0000314	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0	1.2	GO:0005865	striated muscle thin filament(GO:0005865)
0.0	7.2	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.3	GO:0061700	GATOR2 complex(GO:0061700)
0.0	0.9	GO:0001533	cornified envelope(GO:0001533)
0.0	1.0	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.2	GO:0070852	cell body fiber(GO:0070852)
0.0	1.6	GO:0005930	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	0.8	GO:0042629	mast cell granule(GO:0042629)
0.0	1.0	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.3	GO:0030008	TRAPP complex(GO:0030008)
0.0	19.9	GO:0009986	cell surface(GO:0009986)
0.0	1.0	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.0	0.2	GO:0030896	checkpoint clamp complex(GO:0030896)
0.0	0.5	GO:0038201	TOR complex(GO:0038201)
0.0	0.3	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	0.3	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.0	0.3	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	2.5	GO:0005840	ribosome(GO:0005840)
0.0	0.1	GO:0000811	GINS complex(GO:0000811)
0.0	2.7	GO:0001650	fibrillar center(GO:0001650)
0.0	0.5	GO:0045095	keratin filament(GO:0045095)
0.0	0.2	GO:0042599	lamellar body(GO:0042599)
0.0	2.8	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.1	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0	0.4	GO:0005771	multivesicular body(GO:0005771)
0.0	1.0	GO:0035579	specific granule membrane(GO:0035579)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
9.7	38.8	GO:0070320	inward rectifier potassium channel inhibitor activity(GO:0070320)
3.6	10.7	GO:0060422	peptidyl-dipeptidase inhibitor activity(GO:0060422)
3.0	38.7	GO:0048407	platelet-derived growth factor binding(GO:0048407)
2.8	11.2	GO:0004598	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
2.1	6.2	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
2.0	6.0	GO:0060001	minus-end directed microfilament motor activity(GO:0060001)
2.0	6.0	GO:0080023	3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
2.0	5.9	GO:0034189	very-low-density lipoprotein particle binding(GO:0034189)
1.7	12.0	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
1.7	8.4	GO:1990254	keratin filament binding(GO:1990254)
1.7	5.0	GO:0034736	sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
1.6	11.3	GO:0048408	epidermal growth factor binding(GO:0048408)
1.6	4.8	GO:0046921	glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
1.6	4.8	GO:0004584	dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
1.5	6.1	GO:1990430	extracellular matrix protein binding(GO:1990430)
1.5	6.0	GO:0032184	SUMO polymer binding(GO:0032184)
1.5	8.8	GO:0016361	activin receptor activity, type I(GO:0016361)
1.4	4.1	GO:0004874	aryl hydrocarbon receptor activity(GO:0004874)
1.3	5.4	GO:0038047	beta-endorphin receptor activity(GO:0004979) morphine receptor activity(GO:0038047)
1.3	11.6	GO:0060072	large conductance calcium-activated potassium channel activity(GO:0060072)
1.3	5.1	GO:0047288	monosialoganglioside sialyltransferase activity(GO:0047288)
1.3	14.1	GO:0042301	phosphate ion binding(GO:0042301)
1.2	3.7	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.2	3.6	GO:0004782	sulfinoalanine decarboxylase activity(GO:0004782)
1.2	7.1	GO:0034046	poly(G) binding(GO:0034046)
1.2	5.9	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
1.2	5.9	GO:0044729	hemi-methylated DNA-binding(GO:0044729)
1.1	9.0	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
1.1	11.2	GO:0036310	annealing helicase activity(GO:0036310)
1.1	3.3	GO:0015234	thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
1.1	3.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
1.0	3.0	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.9	9.4	GO:0050692	DBD domain binding(GO:0050692)
0.9	3.7	GO:0019828	aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.9	4.6	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.9	2.8	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
0.9	6.3	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.9	5.4	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.9	4.3	GO:0047280	nicotinamide phosphoribosyltransferase activity(GO:0047280)
0.9	3.4	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
0.8	2.5	GO:0033749	histone demethylase activity (H3-R2 specific)(GO:0033746) histone demethylase activity (H4-R3 specific)(GO:0033749)
0.8	3.3	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.8	8.0	GO:0042731	PH domain binding(GO:0042731)
0.8	8.0	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.8	7.2	GO:0045499	chemorepellent activity(GO:0045499)
0.8	8.0	GO:0008131	primary amine oxidase activity(GO:0008131)
0.8	22.2	GO:0017166	vinculin binding(GO:0017166)
0.8	3.1	GO:0086077	gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.8	8.5	GO:0038132	neuregulin binding(GO:0038132)
0.8	4.5	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.7	3.0	GO:0030274	LIM domain binding(GO:0030274)
0.7	1.5	GO:0030226	apolipoprotein receptor activity(GO:0030226)
0.7	5.1	GO:1904288	BAT3 complex binding(GO:1904288)
0.7	5.8	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
0.7	3.6	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.7	3.5	GO:0070051	fibrinogen binding(GO:0070051)
0.7	5.6	GO:0086083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.7	4.2	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.7	2.1	GO:0098808	mRNA cap binding(GO:0098808)
0.7	2.8	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.7	6.2	GO:0016206	catechol O-methyltransferase activity(GO:0016206)
0.7	3.5	GO:0001010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.7	2.0	GO:0030305	heparanase activity(GO:0030305)
0.7	6.8	GO:0035374	chondroitin sulfate binding(GO:0035374)
0.6	1.3	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.6	2.5	GO:0004001	adenosine kinase activity(GO:0004001)
0.6	4.4	GO:1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.6	3.1	GO:0052845	endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.6	3.1	GO:0017002	activin-activated receptor activity(GO:0017002)
0.6	6.8	GO:0039706	co-receptor binding(GO:0039706)
0.6	3.0	GO:0032181	double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.6	3.0	GO:0034711	inhibin binding(GO:0034711)
0.6	1.8	GO:0004613	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.6	1.8	GO:0000252	C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012)
0.6	1.8	GO:0047322	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.6	4.7	GO:0034235	GPI anchor binding(GO:0034235)
0.6	3.5	GO:0005534	galactose binding(GO:0005534)
0.6	13.9	GO:0001968	fibronectin binding(GO:0001968)
0.6	2.3	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
0.6	2.8	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.6	3.9	GO:0015166	polyol transmembrane transporter activity(GO:0015166)
0.6	2.2	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.6	3.3	GO:0047057	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.5	2.7	GO:0016427	tRNA (cytosine) methyltransferase activity(GO:0016427)
0.5	3.7	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.5	3.1	GO:0050051	leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.5	1.5	GO:0070984	SET domain binding(GO:0070984)
0.5	1.0	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.5	1.5	GO:0004923	leukemia inhibitory factor receptor activity(GO:0004923)
0.5	3.0	GO:0019237	centromeric DNA binding(GO:0019237)
0.5	3.4	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.5	10.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.5	9.7	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.5	4.3	GO:0048185	activin binding(GO:0048185)
0.5	2.4	GO:0033906	hyaluronoglucuronidase activity(GO:0033906)
0.5	0.5	GO:0047977	hepoxilin-epoxide hydrolase activity(GO:0047977)
0.5	18.4	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
0.5	73.3	GO:0005178	integrin binding(GO:0005178)
0.5	1.4	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
0.4	12.2	GO:0005109	frizzled binding(GO:0005109)
0.4	4.4	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.4	4.7	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.4	18.9	GO:0003785	actin monomer binding(GO:0003785)
0.4	5.6	GO:0016405	CoA-ligase activity(GO:0016405)
0.4	3.4	GO:0045159	myosin II binding(GO:0045159)
0.4	6.3	GO:0070411	I-SMAD binding(GO:0070411)
0.4	9.2	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.4	77.6	GO:0008083	growth factor activity(GO:0008083)
0.4	34.5	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.4	1.2	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.4	7.6	GO:0097602	cullin family protein binding(GO:0097602)
0.4	4.8	GO:0001758	retinal dehydrogenase activity(GO:0001758)
0.4	2.0	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.4	4.7	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.4	2.0	GO:0046899	nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.4	5.1	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.4	1.1	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.4	1.9	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.4	7.3	GO:0030296	protein tyrosine kinase activator activity(GO:0030296)
0.4	1.5	GO:0019107	glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.4	1.8	GO:0048763	calcium-induced calcium release activity(GO:0048763)
0.4	1.8	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.4	1.4	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.4	4.3	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.4	1.4	GO:0035800	deubiquitinase activator activity(GO:0035800)
0.4	1.4	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
0.4	1.1	GO:0016429	tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.4	6.0	GO:0042809	vitamin D receptor binding(GO:0042809)
0.3	5.9	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.3	1.4	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.3	2.4	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.3	6.8	GO:0035497	cAMP response element binding(GO:0035497)
0.3	8.8	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.3	1.7	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.3	1.0	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.3	2.3	GO:0001640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.3	1.7	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.3	4.6	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.3	16.4	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.3	1.3	GO:0052591	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.3	1.3	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.3	1.3	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.3	2.2	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.3	1.3	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.3	1.3	GO:0018271	biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
0.3	3.8	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.3	2.2	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.3	2.2	GO:0004465	lipoprotein lipase activity(GO:0004465)
0.3	1.6	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.3	3.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.3	1.8	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.3	1.5	GO:0004370	glycerol kinase activity(GO:0004370)
0.3	8.7	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
0.3	1.2	GO:0035939	microsatellite binding(GO:0035939)
0.3	0.6	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.3	0.9	GO:0032142	single guanine insertion binding(GO:0032142)
0.3	1.4	GO:0001594	trace-amine receptor activity(GO:0001594)
0.3	1.7	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.3	0.9	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.3	1.4	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.3	3.1	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.3	0.8	GO:0033699	DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
0.3	2.5	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.3	1.7	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.3	1.4	GO:0044547	DNA topoisomerase binding(GO:0044547)
0.3	3.6	GO:0005520	insulin-like growth factor binding(GO:0005520)
0.3	1.7	GO:0031962	mineralocorticoid receptor binding(GO:0031962)
0.3	5.7	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.3	0.8	GO:0034437	glycoprotein transporter activity(GO:0034437)
0.3	1.1	GO:0004461	lactose synthase activity(GO:0004461)
0.3	0.8	GO:0003974	UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.3	0.3	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
0.3	1.1	GO:0032810	sterol response element binding(GO:0032810)
0.3	0.8	GO:0050698	proteoglycan sulfotransferase activity(GO:0050698)
0.3	1.8	GO:0043522	leucine zipper domain binding(GO:0043522)
0.2	3.5	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.2	1.0	GO:0043237	laminin-1 binding(GO:0043237)
0.2	0.7	GO:0004421	hydroxymethylglutaryl-CoA synthase activity(GO:0004421)
0.2	1.5	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.2	1.7	GO:0051011	microtubule minus-end binding(GO:0051011)
0.2	7.1	GO:0001972	retinoic acid binding(GO:0001972)
0.2	2.9	GO:0019215	intermediate filament binding(GO:0019215)
0.2	1.9	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2	1.2	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.2	3.8	GO:0044213	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2	2.8	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.2	23.6	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.2	25.0	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.2	0.2	GO:0050682	AF-2 domain binding(GO:0050682)
0.2	0.9	GO:0005277	acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.2	20.2	GO:0008307	structural constituent of muscle(GO:0008307)
0.2	3.3	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.2	2.1	GO:0000150	recombinase activity(GO:0000150)
0.2	0.9	GO:0005113	patched binding(GO:0005113)
0.2	1.1	GO:0004910	interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.2	0.7	GO:0015616	DNA translocase activity(GO:0015616)
0.2	3.5	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.2	5.4	GO:0004697	protein kinase C activity(GO:0004697)
0.2	1.7	GO:0043426	MRF binding(GO:0043426)
0.2	0.9	GO:0035500	MH2 domain binding(GO:0035500)
0.2	2.6	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.2	1.3	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.2	11.4	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2	0.6	GO:1990190	peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.2	1.9	GO:0034056	estrogen response element binding(GO:0034056)
0.2	1.3	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.2	0.8	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2	8.2	GO:0001221	transcription cofactor binding(GO:0001221)
0.2	2.1	GO:0031013	troponin I binding(GO:0031013)
0.2	4.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.2	1.0	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2	1.0	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.2	3.0	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.2	3.0	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.2	1.8	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.2	0.6	GO:0008384	IkappaB kinase activity(GO:0008384)
0.2	1.5	GO:0004996	thyroid-stimulating hormone receptor activity(GO:0004996)
0.2	1.3	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.2	2.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.2	0.8	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.2	3.9	GO:0070888	E-box binding(GO:0070888)
0.2	1.3	GO:0050815	phosphoserine binding(GO:0050815)
0.2	6.4	GO:0030332	cyclin binding(GO:0030332)
0.2	2.3	GO:0032052	bile acid binding(GO:0032052)
0.2	0.7	GO:0004146	dihydrofolate reductase activity(GO:0004146)
0.2	1.2	GO:0008172	S-methyltransferase activity(GO:0008172)
0.2	1.0	GO:0016918	retinal binding(GO:0016918)
0.2	1.2	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.2	0.7	GO:0004102	choline O-acetyltransferase activity(GO:0004102)
0.2	0.5	GO:0070573	metallodipeptidase activity(GO:0070573)
0.2	69.0	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.2	1.5	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.2	3.4	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.2	0.2	GO:0061629	titin binding(GO:0031432) RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2	6.5	GO:0050840	extracellular matrix binding(GO:0050840)
0.2	0.7	GO:0008046	axon guidance receptor activity(GO:0008046)
0.2	2.5	GO:0005112	Notch binding(GO:0005112)
0.2	0.8	GO:0015094	cadmium ion transmembrane transporter activity(GO:0015086) cobalt ion transmembrane transporter activity(GO:0015087) ferrous iron transmembrane transporter activity(GO:0015093) lead ion transmembrane transporter activity(GO:0015094) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.2	2.0	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.2	3.1	GO:0005537	mannose binding(GO:0005537)
0.2	6.9	GO:0005044	scavenger receptor activity(GO:0005044)
0.2	2.1	GO:0005003	ephrin receptor activity(GO:0005003)
0.2	11.7	GO:0008013	beta-catenin binding(GO:0008013)
0.2	0.8	GO:0005499	vitamin D binding(GO:0005499)
0.2	3.2	GO:0008409	5'-3' exonuclease activity(GO:0008409)
0.2	2.0	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.2	1.7	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.2	0.5	GO:0032027	myosin light chain binding(GO:0032027)
0.2	2.1	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.2	3.3	GO:0000030	mannosyltransferase activity(GO:0000030)
0.2	1.5	GO:0015250	water channel activity(GO:0015250)
0.1	4.6	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1	1.9	GO:0008527	taste receptor activity(GO:0008527)
0.1	0.9	GO:0097617	annealing activity(GO:0097617)
0.1	2.9	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.1	1.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.1	1.0	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1	0.6	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.1	4.3	GO:0051059	NF-kappaB binding(GO:0051059)
0.1	1.7	GO:0019957	C-C chemokine binding(GO:0019957)
0.1	2.7	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.1	1.0	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
0.1	3.8	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1	4.7	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	0.7	GO:0070576	vitamin D 24-hydroxylase activity(GO:0070576)
0.1	0.5	GO:0004948	calcitonin receptor activity(GO:0004948)
0.1	0.4	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072) transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.1	1.5	GO:0004118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1	1.5	GO:0017049	GTP-Rho binding(GO:0017049)
0.1	0.9	GO:1990459	transferrin receptor binding(GO:1990459)
0.1	0.4	GO:0036487	nitric-oxide synthase inhibitor activity(GO:0036487)
0.1	3.5	GO:0031434	mitogen-activated protein kinase kinase binding(GO:0031434)
0.1	0.4	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1	1.5	GO:0051378	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1	1.1	GO:0032036	myosin heavy chain binding(GO:0032036)
0.1	1.2	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1	4.8	GO:0043022	ribosome binding(GO:0043022)
0.1	1.8	GO:0051010	microtubule plus-end binding(GO:0051010)
0.1	1.6	GO:0015245	fatty acid transporter activity(GO:0015245)
0.1	0.8	GO:0004797	thymidine kinase activity(GO:0004797)
0.1	0.5	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.1	0.1	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
0.1	1.7	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.1	3.0	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	0.8	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1	2.1	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.1	0.7	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.1	0.3	GO:0015275	stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1	0.3	GO:0098973	structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.1	1.5	GO:0010181	FMN binding(GO:0010181)
0.1	3.8	GO:0035591	signaling adaptor activity(GO:0035591)
0.1	0.2	GO:0035402	histone kinase activity (H3-T11 specific)(GO:0035402)
0.1	0.3	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1	0.2	GO:0004660	protein farnesyltransferase activity(GO:0004660)
0.1	1.2	GO:0016594	glycine binding(GO:0016594)
0.1	0.8	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.1	0.2	GO:0035184	histone threonine kinase activity(GO:0035184)
0.1	0.5	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1	1.4	GO:0016854	racemase and epimerase activity(GO:0016854)
0.1	0.7	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1	0.5	GO:0019776	Atg8 ligase activity(GO:0019776)
0.1	0.7	GO:0015186	L-glutamine transmembrane transporter activity(GO:0015186)
0.1	0.3	GO:0015116	sulfate transmembrane transporter activity(GO:0015116)
0.1	0.3	GO:0061752	telomeric repeat-containing RNA binding(GO:0061752)
0.1	5.3	GO:0001085	RNA polymerase II transcription factor binding(GO:0001085)
0.1	3.1	GO:0051183	vitamin transporter activity(GO:0051183)
0.1	1.1	GO:0016274	arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274)
0.1	2.8	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.1	0.5	GO:0039552	RIG-I binding(GO:0039552)
0.1	0.3	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.1	1.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.1	0.8	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
0.1	2.6	GO:0070182	DNA polymerase binding(GO:0070182)
0.1	2.7	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.1	2.2	GO:0008483	transaminase activity(GO:0008483)
0.1	0.8	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1	0.4	GO:0004966	galanin receptor activity(GO:0004966)
0.1	1.6	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1	2.4	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	1.4	GO:0001786	phosphatidylserine binding(GO:0001786)
0.1	0.3	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.1	2.2	GO:0016702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1	1.3	GO:0071837	HMG box domain binding(GO:0071837)
0.1	0.4	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1	0.5	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.1	9.6	GO:0020037	heme binding(GO:0020037)
0.1	1.0	GO:0008649	rRNA methyltransferase activity(GO:0008649)
0.1	0.4	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.1	1.4	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1	0.5	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1	1.2	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1	8.0	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	1.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	7.1	GO:0005254	chloride channel activity(GO:0005254)
0.1	0.4	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.1	0.4	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1	0.6	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.1	0.5	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.1	2.2	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.1	1.0	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	0.3	GO:0004348	glucosylceramidase activity(GO:0004348)
0.1	1.4	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.1	5.6	GO:0019003	GDP binding(GO:0019003)
0.1	0.6	GO:0051184	cofactor transporter activity(GO:0051184)
0.1	2.1	GO:0048487	beta-tubulin binding(GO:0048487)
0.1	0.3	GO:0000405	bubble DNA binding(GO:0000405)
0.1	0.4	GO:0031708	endothelin B receptor binding(GO:0031708)
0.1	2.0	GO:0008188	neuropeptide receptor activity(GO:0008188)
0.1	1.1	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.1	1.4	GO:0003707	steroid hormone receptor activity(GO:0003707)
0.1	0.4	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.4	GO:0017040	ceramidase activity(GO:0017040)
0.1	7.4	GO:0004896	cytokine receptor activity(GO:0004896)
0.1	0.2	GO:0047751	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1	0.9	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.1	1.0	GO:0008569	ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1	1.6	GO:0042166	acetylcholine binding(GO:0042166)
0.1	0.5	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.1	0.2	GO:0004878	complement component C5a receptor activity(GO:0004878)
0.1	0.6	GO:0005243	gap junction channel activity(GO:0005243)
0.1	0.2	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.1	0.6	GO:0004017	adenylate kinase activity(GO:0004017)
0.1	0.3	GO:0036033	mediator complex binding(GO:0036033)
0.1	2.2	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1	1.3	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.1	1.4	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.4	GO:0004993	G-protein coupled serotonin receptor activity(GO:0004993)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.3	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.7	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.1	GO:0008511	sodium:potassium:chloride symporter activity(GO:0008511)
0.0	0.7	GO:0008175	tRNA methyltransferase activity(GO:0008175)
0.0	0.4	GO:0102338	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.6	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.6	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.0	0.4	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.6	GO:0008417	fucosyltransferase activity(GO:0008417)
0.0	0.8	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.3	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.3	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.2	GO:0030548	acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602)
0.0	0.6	GO:0048156	tau protein binding(GO:0048156)
0.0	0.3	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.3	GO:0035197	siRNA binding(GO:0035197)
0.0	4.2	GO:0000982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.3	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.7	GO:0000049	tRNA binding(GO:0000049)
0.0	0.6	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	10.7	GO:0045296	cadherin binding(GO:0045296)
0.0	0.4	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.3	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0	0.2	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.4	GO:0031005	filamin binding(GO:0031005)
0.0	0.6	GO:0005123	death receptor binding(GO:0005123)
0.0	0.8	GO:0008028	monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0	1.4	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0	0.4	GO:1901612	cardiolipin binding(GO:1901612)
0.0	3.7	GO:0001228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0	0.2	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.8	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.8	GO:0022839	ion gated channel activity(GO:0022839)
0.0	0.8	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.2	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	0.5	GO:0070566	adenylyltransferase activity(GO:0070566)
0.0	1.7	GO:0004984	olfactory receptor activity(GO:0004984)
0.0	0.2	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.3	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.4	GO:0051721	protein phosphatase 2A binding(GO:0051721)
0.0	1.6	GO:0005179	hormone activity(GO:0005179)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.1	GO:0005158	insulin receptor binding(GO:0005158)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.5	105.6	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
1.3	63.6	NABA COLLAGENS	Genes encoding collagen proteins
1.2	47.9	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
1.1	15.3	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.7	13.7	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.7	52.6	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.7	8.2	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.7	15.4	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.6	3.8	PID ALK1 PATHWAY	ALK1 signaling events
0.6	32.0	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.6	11.4	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.6	6.7	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.5	15.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.5	0.5	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.5	4.6	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.4	8.9	PID ALK2 PATHWAY	ALK2 signaling events
0.4	16.0	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.4	6.4	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.4	2.0	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.4	22.3	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.4	2.9	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.4	6.0	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.3	6.4	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.3	11.6	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3	12.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.3	12.9	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.3	5.5	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.3	8.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.3	26.0	PID CASPASE PATHWAY	Caspase cascade in apoptosis
0.3	14.3	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.3	1.9	ST G ALPHA S PATHWAY	G alpha s Pathway
0.3	17.2	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.3	2.9	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.2	10.6	ST GA13 PATHWAY	G alpha 13 Pathway
0.2	9.4	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.2	7.1	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.2	40.9	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.2	4.6	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.2	16.8	PID TELOMERASE PATHWAY	Regulation of Telomerase
0.2	1.8	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.2	8.0	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.2	9.8	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.2	6.7	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.2	2.4	PID AURORA A PATHWAY	Aurora A signaling
0.2	42.9	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.2	9.7	ST FAS SIGNALING PATHWAY	Fas Signaling Pathway
0.2	2.1	ST GA12 PATHWAY	G alpha 12 Pathway
0.1	2.7	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1	7.1	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	1.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	2.3	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.1	1.7	PID IL2 1PATHWAY	IL2-mediated signaling events
0.1	0.5	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.1	1.8	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.1	6.0	PID MTOR 4PATHWAY	mTOR signaling pathway
0.1	1.9	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.1	2.6	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.1	1.7	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.1	5.1	PID FGF PATHWAY	FGF signaling pathway
0.1	1.7	PID EPHA FWDPATHWAY	EPHA forward signaling
0.1	17.8	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	0.4	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.1	1.0	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.1	7.7	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.1	8.3	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.1	0.7	PID RHOA PATHWAY	RhoA signaling pathway
0.1	22.9	NABA SECRETED FACTORS	Genes encoding secreted soluble factors
0.1	1.1	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.1	2.5	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.1	2.2	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	1.2	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.1	3.6	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	0.6	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.1	0.9	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.1	1.2	PID CDC42 PATHWAY	CDC42 signaling events
0.1	0.7	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.0	0.5	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0	0.6	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	2.1	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.2	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	2.4	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.6	PID BCR 5PATHWAY	BCR signaling pathway
0.0	1.7	NABA MATRISOME	Ensemble of genes encoding extracellular matrix and extracellular matrix-associated proteins
0.0	0.8	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.5	PID BMP PATHWAY	BMP receptor signaling
0.0	1.3	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	2.5	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.4	PID IL27 PATHWAY	IL27-mediated signaling events
0.0	0.4	PID ATM PATHWAY	ATM pathway
0.0	0.8	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	1.4	PID P73PATHWAY	p73 transcription factor network
0.0	1.0	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.2	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.0	0.1	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.3	4.5	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
1.7	44.9	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
1.3	85.1	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
1.2	1.2	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
1.1	38.0	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
1.1	23.9	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.8	27.6	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.7	22.4	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.6	20.7	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.6	10.2	REACTOME ZINC TRANSPORTERS	Genes involved in Zinc transporters
0.6	19.7	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.5	9.8	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.5	10.1	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.5	24.0	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.5	67.0	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.5	7.3	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.4	3.1	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.4	8.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.4	8.5	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.3	3.6	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.3	32.9	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.3	4.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.3	4.1	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.3	2.0	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.3	2.3	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.3	1.6	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.3	1.9	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.3	6.5	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.3	3.4	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.3	5.9	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.3	3.0	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.2	8.4	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.2	10.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.2	3.4	REACTOME SEROTONIN RECEPTORS	Genes involved in Serotonin receptors
0.2	2.6	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.2	4.2	REACTOME G PROTEIN ACTIVATION	Genes involved in G-protein activation
0.2	1.5	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.2	2.8	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.2	10.6	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.2	1.9	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.2	6.8	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.2	10.5	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.2	12.3	REACTOME CELL JUNCTION ORGANIZATION	Genes involved in Cell junction organization
0.2	1.4	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.2	2.0	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.2	0.8	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2	1.7	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.2	6.8	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.2	2.7	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.2	7.4	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.2	3.1	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.2	3.4	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.2	6.9	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.2	2.9	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.2	2.8	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.2	3.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.2	1.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.2	2.2	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2	1.3	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.2	3.0	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.2	2.5	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.2	1.8	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.2	1.8	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1	4.6	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	5.5	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.1	1.6	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.1	1.7	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	2.2	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.1	6.1	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.1	2.1	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1	6.9	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.1	1.7	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.1	2.0	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	2.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1	2.6	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	10.3	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.1	1.8	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.1	3.2	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.1	2.8	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.1	2.0	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	2.5	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	0.5	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.1	1.4	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1	3.5	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.1	0.7	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1	1.6	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.1	0.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	0.4	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
0.1	10.5	REACTOME DIABETES PATHWAYS	Genes involved in Diabetes pathways
0.1	1.4	REACTOME GPCR LIGAND BINDING	Genes involved in GPCR ligand binding
0.1	2.3	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	2.8	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.1	1.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.1	0.9	REACTOME SLC MEDIATED TRANSMEMBRANE TRANSPORT	Genes involved in SLC-mediated transmembrane transport
0.1	3.8	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.1	1.6	REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1	3.7	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.1	1.4	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	0.7	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.1	1.1	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	12.2	REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION	Genes involved in 3' -UTR-mediated translational regulation
0.1	1.2	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1	2.0	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.1	1.6	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1	1.8	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	3.6	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.1	0.8	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.1	1.5	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.1	0.2	REACTOME PLATELET AGGREGATION PLUG FORMATION	Genes involved in Platelet Aggregation (Plug Formation)
0.1	2.9	REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS	Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.0	0.8	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	1.3	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0	1.8	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	1.3	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.4	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.9	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.0	0.8	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	1.4	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	1.4	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	3.6	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.3	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.8	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.1	REACTOME DSCAM INTERACTIONS	Genes involved in DSCAM interactions
0.0	0.2	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	1.2	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.2	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	4.3	REACTOME GENERIC TRANSCRIPTION PATHWAY	Genes involved in Generic Transcription Pathway
0.0	0.4	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	3.9	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.0	0.4	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.0	1.7	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.2	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.2	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.4	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.4	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.1	REACTOME TRANSMEMBRANE TRANSPORT OF SMALL MOLECULES	Genes involved in Transmembrane transport of small molecules
0.0	0.1	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport

Results for E2F6

Z-value: 0.37

Motif logo

Transcription factors associated with E2F6

Activity-expression correlation:

Activity profile of E2F6 motif

Sorted Z-values of E2F6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F6

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: