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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for E2F7_E2F1

Z-value: 16.45

Motif logo

Transcription factors associated with E2F7_E2F1

Gene Symbol Gene ID Gene Info
ENSG00000165891.16 E2F7
ENSG00000101412.13 E2F1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F1hg38_v1_chr20_-_33686371_336864070.741.0e-39Click!

Activity profile of E2F7_E2F1 motif

Sorted Z-values of E2F7_E2F1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F7_E2F1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr2_+_10123171 222.22 ENST00000615152.5
ribonucleotide reductase regulatory subunit M2
chr11_+_4094775 161.76 ENST00000300738.10
ribonucleotide reductase catalytic subunit M1
chr2_+_10122730 156.49 ENST00000304567.10
ribonucleotide reductase regulatory subunit M2
chr18_+_657637 155.63 ENST00000323274.15
thymidylate synthetase
chr18_+_657734 151.40 ENST00000323250.9
ENST00000323224.7
thymidylate synthetase
chr7_-_100100716 138.84 ENST00000354230.7
ENST00000425308.5
minichromosome maintenance complex component 7
chr4_-_173333672 132.38 ENST00000438704.6
high mobility group box 2
chr2_+_47403116 130.97 ENST00000645506.1
ENST00000406134.5
ENST00000233146.7
mutS homolog 2
chr2_+_47403061 125.54 ENST00000543555.6
mutS homolog 2
chr6_-_52284677 121.54 ENST00000596288.7
ENST00000616552.4
ENST00000229854.12
ENST00000419835.8
minichromosome maintenance complex component 3
chr22_+_20117734 120.78 ENST00000416427.5
ENST00000421656.5
ENST00000423859.5
ENST00000418705.2
RAN binding protein 1
chr7_-_100101915 120.37 ENST00000621318.4
ENST00000343023.10
minichromosome maintenance complex component 7
chr6_-_18264175 117.10 ENST00000651992.1
ENST00000652576.1
DEK proto-oncogene
chr6_-_18264475 116.10 ENST00000515742.2
ENST00000651624.1
ENST00000507591.2
ENST00000652689.1
ENST00000244776.11
ENST00000503715.5
DEK proto-oncogene
chr4_-_1712310 114.65 ENST00000488267.5
ENST00000429429.6
ENST00000489418.6
ENST00000480936.1
stem-loop binding protein
chr17_-_78187036 109.46 ENST00000590862.5
ENST00000590430.5
ENST00000301634.12
ENST00000586613.1
thymidine kinase 1
chr5_+_126777112 107.08 ENST00000261366.10
ENST00000492190.5
ENST00000395354.1
lamin B1
chr7_-_100101333 103.75 ENST00000303887.10
minichromosome maintenance complex component 7
chr13_+_33818122 101.30 ENST00000380071.8
replication factor C subunit 3
chr15_-_64381431 99.85 ENST00000558008.3
ENST00000300035.9
ENST00000559519.5
ENST00000380258.6
PCNA clamp associated factor
chr7_-_148884159 99.36 ENST00000478654.5
ENST00000460911.5
ENST00000350995.6
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr7_-_148884266 99.07 ENST00000483967.5
ENST00000320356.7
enhancer of zeste 2 polycomb repressive complex 2 subunit
chr12_+_95858928 98.80 ENST00000266735.9
ENST00000553192.5
ENST00000552085.1
small nuclear ribonucleoprotein polypeptide F
chr14_+_93207229 94.32 ENST00000554232.5
ENST00000556871.5
ENST00000013070.11
ENST00000555113.5
ubiquitin protein ligase E3 component n-recognin 7
chr2_+_171922442 94.04 ENST00000264108.5
histone acetyltransferase 1
chr7_-_158704740 92.25 ENST00000409339.3
ENST00000356309.8
ENST00000409423.5
non-SMC condensin II complex subunit G2
chr12_-_57752265 91.57 ENST00000547281.5
ENST00000257904.11
ENST00000546489.5
ENST00000552388.1
cyclin dependent kinase 4
chr4_+_56436131 90.86 ENST00000399688.7
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
chr6_+_30720335 90.27 ENST00000327892.13
tubulin beta class I
chr12_-_57752345 88.93 ENST00000551800.5
ENST00000549606.5
ENST00000312990.10
cyclin dependent kinase 4
chr22_+_20117497 88.04 ENST00000331821.7
ENST00000411892.5
RAN binding protein 1
chr4_-_173334249 87.30 ENST00000506267.1
ENST00000296503.10
high mobility group box 2
chr20_-_2470749 86.27 ENST00000381342.7
ENST00000438552.6
small nuclear ribonucleoprotein polypeptides B and B1
chrX_+_107628428 84.54 ENST00000643795.2
ENST00000372418.4
ENST00000646815.1
ENST00000372435.10
ENST00000372419.3
ENST00000676092.1
phosphoribosyl pyrophosphate synthetase 1
chr16_-_85688912 83.85 ENST00000253462.8
GINS complex subunit 2
chr1_-_53945661 83.11 ENST00000194214.10
heat shock protein family B (small) member 11
chr4_+_56435730 82.32 ENST00000514888.5
ENST00000264221.6
ENST00000505164.5
phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase
chr10_-_73247241 79.35 ENST00000372950.6
DnaJ heat shock protein family (Hsp40) member C9
chr11_-_57335854 77.67 ENST00000529002.2
ENST00000278412.7
structure specific recognition protein 1
chr8_-_120445140 75.45 ENST00000306185.8
mitochondrial ribosomal protein L13
chr16_-_11915991 75.21 ENST00000420576.6
G1 to S phase transition 1
chr6_-_17706748 73.34 ENST00000613258.4
ENST00000537253.5
nucleoporin 153
chr4_-_169757873 71.48 ENST00000393381.3
histone PARylation factor 1
chr2_-_135876382 70.64 ENST00000264156.3
minichromosome maintenance complex component 6
chr4_-_76148382 70.19 ENST00000264883.8
ENST00000514987.5
ENST00000514901.5
nucleoporin 54
chr9_+_104094557 69.75 ENST00000374787.7
structural maintenance of chromosomes 2
chr19_-_48170323 69.74 ENST00000263274.12
ENST00000427526.6
DNA ligase 1
chr12_-_56752311 69.60 ENST00000338193.11
ENST00000550770.1
DNA primase subunit 1
chr14_+_104753120 69.20 ENST00000535554.4
ENST00000329967.11
ENST00000347067.9
ENST00000553810.5
SIVA1 apoptosis inducing factor
chr8_+_127736046 68.62 ENST00000641036.1
ENST00000377970.6
MYC proto-oncogene, bHLH transcription factor
chr2_-_38751350 68.03 ENST00000409276.5
ENST00000313117.11
ENST00000446327.6
serine and arginine rich splicing factor 7
chr21_-_33588624 65.39 ENST00000437395.5
ENST00000453626.5
ENST00000303113.10
ENST00000303071.10
ENST00000432378.5
DNA replication fork stabilization factor DONSON
chr13_+_37000774 64.59 ENST00000389704.4
exosome component 8
chr8_+_47960883 63.21 ENST00000648407.1
ENST00000649838.1
ENST00000649919.1
ENST00000262105.6
ENST00000649973.1
minichromosome maintenance complex component 4
chr8_+_127736220 62.56 ENST00000524013.2
ENST00000621592.8
MYC proto-oncogene, bHLH transcription factor
chr6_-_17706852 62.40 ENST00000262077.3
nucleoporin 153
chr2_+_47783172 61.12 ENST00000540021.6
mutS homolog 6
chr16_-_8868994 60.42 ENST00000311052.10
ENST00000565287.5
ENST00000611932.4
calcium regulated heat stable protein 1
chr20_+_43667105 59.99 ENST00000217026.5
MYB proto-oncogene like 2
chr5_-_80654552 59.61 ENST00000511032.5
ENST00000504396.1
ENST00000505337.5
dihydrofolate reductase
chr20_+_62796432 59.48 ENST00000370487.5
MRG domain binding protein
chr12_-_56752366 59.44 ENST00000672280.1
DNA primase subunit 1
chr8_-_123396412 59.16 ENST00000287394.10
ATPase family AAA domain containing 2
chr11_+_86244745 58.68 ENST00000528180.5
ENST00000263360.11
ENST00000672825.1
embryonic ectoderm development
chr5_+_178204522 58.64 ENST00000506339.5
ENST00000358344.8
ENST00000355836.9
ENST00000514633.5
ENST00000515193.5
ENST00000506259.5
ENST00000504898.5
heterogeneous nuclear ribonucleoprotein A/B
chr2_+_180980566 58.58 ENST00000410062.9
ubiquitin conjugating enzyme E2 E3
chr14_-_105021043 58.32 ENST00000392590.3
ENST00000336219.4
cell division cycle associated 4
chr2_+_27217361 57.43 ENST00000264705.9
ENST00000403525.5
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr5_-_80654956 57.36 ENST00000439211.7
dihydrofolate reductase
chr12_+_4538830 56.66 ENST00000228843.13
ENST00000352618.9
ENST00000544927.5
RAD51 associated protein 1
chr1_-_23980345 56.57 ENST00000484146.6
serine and arginine rich splicing factor 10
chr12_-_56688156 56.39 ENST00000436399.6
prostaglandin E synthase 3
chr16_-_50368920 56.23 ENST00000394688.8
bromodomain containing 7
chr1_+_32651142 56.23 ENST00000414241.7
RB binding protein 4, chromatin remodeling factor
chr10_-_17617235 56.14 ENST00000466335.1
3-hydroxyacyl-CoA dehydratase 1
chr10_-_43396831 55.74 ENST00000443950.6
heterogeneous nuclear ribonucleoprotein F
chrX_-_53422170 55.56 ENST00000675504.1
structural maintenance of chromosomes 1A
chr16_-_50368779 55.32 ENST00000394689.2
bromodomain containing 7
chr12_+_69239592 54.91 ENST00000456847.7
ENST00000266679.8
cleavage and polyadenylation specific factor 6
chr15_+_48332103 54.79 ENST00000455976.6
ENST00000559540.5
deoxyuridine triphosphatase
chr7_-_26200734 54.78 ENST00000354667.8
ENST00000618183.5
heterogeneous nuclear ribonucleoprotein A2/B1
chr2_+_180980347 54.11 ENST00000602959.5
ENST00000602479.5
ENST00000392415.6
ENST00000602291.5
ubiquitin conjugating enzyme E2 E3
chr8_+_47961028 53.69 ENST00000650216.1
minichromosome maintenance complex component 4
chr22_+_19479826 53.48 ENST00000437685.6
ENST00000263201.7
ENST00000404724.7
cell division cycle 45
chr18_+_31498168 50.68 ENST00000261590.13
ENST00000585206.1
ENST00000683654.1
desmoglein 2
chr2_+_216109323 50.67 ENST00000392132.7
ENST00000417391.1
X-ray repair cross complementing 5
chrX_+_150983299 50.62 ENST00000325307.12
high mobility group box 3
chr10_+_123154414 50.58 ENST00000368858.9
BUB3 mitotic checkpoint protein
chr7_-_73522278 50.56 ENST00000404251.1
ENST00000339594.9
bromodomain adjacent to zinc finger domain 1B
chr17_-_50397472 50.33 ENST00000576448.1
ENST00000225972.8
leucine rich repeat containing 59
chr1_-_33036927 50.31 ENST00000354858.11
adenylate kinase 2
chr1_+_26472459 50.25 ENST00000619352.4
high mobility group nucleosomal binding domain 2
chr7_+_157138912 50.16 ENST00000611269.4
ENST00000348165.10
ubiquitin protein ligase E3C
chr2_-_27409523 50.04 ENST00000344034.5
protein phosphatase, Mg2+/Mn2+ dependent 1G
chr22_+_35400115 49.87 ENST00000382011.9
ENST00000216122.9
ENST00000416905.1
minichromosome maintenance complex component 5
chr1_+_86704892 49.83 ENST00000482504.1
SH3 domain containing GRB2 like, endophilin B1
chr2_-_214809597 49.62 ENST00000619009.5
ENST00000421162.2
ENST00000617164.5
ENST00000613374.5
ENST00000620057.4
BRCA1 associated RING domain 1
chr19_+_571274 49.51 ENST00000545507.6
ENST00000346916.9
basigin (Ok blood group)
chr11_+_65919331 48.91 ENST00000376991.6
DR1 associated protein 1
chr10_+_14838288 48.83 ENST00000640019.3
ENST00000493178.1
ENST00000378372.8
novel protein
heat shock protein family A (Hsp70) member 14
chr19_-_49929454 48.54 ENST00000597723.5
ENST00000599788.1
ENST00000352066.8
ENST00000596217.1
ENST00000593652.5
ENST00000599567.5
ENST00000600935.1
ENST00000596011.1
ENST00000596022.5
ENST00000597295.5
nucleoporin 62
interleukin 4 induced 1
chr1_+_156082563 48.36 ENST00000368301.6
lamin A/C
chr22_+_35257452 48.25 ENST00000420166.5
ENST00000216106.6
ENST00000455359.5
HMG-box containing 4
chr12_+_69239627 47.90 ENST00000551516.1
cleavage and polyadenylation specific factor 6
chr14_-_21383989 47.66 ENST00000216297.7
SPT16 homolog, facilitates chromatin remodeling subunit
chr6_-_159789660 47.38 ENST00000538128.5
ENST00000537390.5
ENST00000392168.6
t-complex 1
chr1_-_197146620 47.16 ENST00000367409.9
ENST00000680265.1
assembly factor for spindle microtubules
chr1_+_32651164 47.08 ENST00000373493.10
ENST00000373485.5
ENST00000458695.6
RB binding protein 4, chromatin remodeling factor
chr1_-_197146688 46.98 ENST00000294732.11
assembly factor for spindle microtubules
chr6_-_158644709 46.95 ENST00000367089.8
dynein light chain Tctex-type 1
chr7_-_74254362 46.71 ENST00000352131.7
ENST00000055077.8
ENST00000621097.4
replication factor C subunit 2
chr3_-_186806445 46.66 ENST00000418288.5
ENST00000296273.7
replication factor C subunit 4
chr2_-_58241259 46.65 ENST00000481670.2
ENST00000403676.5
ENST00000427708.6
ENST00000403295.7
ENST00000233741.9
ENST00000446381.5
ENST00000417361.1
ENST00000402135.7
ENST00000449070.5
FA complementation group L
chr9_+_124869126 46.52 ENST00000259477.6
actin related protein 2/3 complex subunit 5 like
chr1_+_212035717 46.49 ENST00000366991.5
denticleless E3 ubiquitin protein ligase homolog
chr6_+_30717433 45.92 ENST00000681435.1
tubulin beta class I
chr1_+_91501097 45.59 ENST00000428239.5
ENST00000426137.1
cell division cycle 7
chr18_-_56651122 45.57 ENST00000590954.5
thioredoxin like 1
chr15_+_41332862 45.35 ENST00000450592.6
ENST00000414849.6
ENST00000559596.6
ENST00000560747.5
ENST00000560177.5
nucleolar and spindle associated protein 1
chr11_+_65919261 45.28 ENST00000525501.5
DR1 associated protein 1
chr19_+_40751179 45.19 ENST00000243563.8
ENST00000601393.1
small nuclear ribonucleoprotein polypeptide A
chr6_-_111483700 45.18 ENST00000435970.5
ENST00000358835.7
REV3 like, DNA directed polymerase zeta catalytic subunit
chr1_+_91500827 44.97 ENST00000234626.11
cell division cycle 7
chr10_+_60778331 44.82 ENST00000519078.6
ENST00000316629.8
ENST00000395284.8
cyclin dependent kinase 1
chr10_-_17617326 44.55 ENST00000326961.6
ENST00000361271.8
3-hydroxyacyl-CoA dehydratase 1
chr16_-_8868687 44.37 ENST00000618335.4
ENST00000570125.5
calcium regulated heat stable protein 1
chr17_-_30291930 44.30 ENST00000261714.11
bleomycin hydrolase
chr2_+_84971093 44.09 ENST00000456682.1
ENST00000409785.9
potassium channel modulatory factor 1
chrX_-_154479253 43.62 ENST00000357360.4
L antigen family member 3
chr5_+_72816643 43.58 ENST00000337273.10
ENST00000523768.5
transportin 1
chr12_-_112418819 43.55 ENST00000551291.6
ribosomal protein L6
chr1_-_8879170 43.54 ENST00000489867.2
enolase 1
chr5_+_168486462 43.52 ENST00000231572.8
ENST00000626454.1
arginyl-tRNA synthetase 1
chr2_-_214809650 43.03 ENST00000260947.9
ENST00000613706.5
BRCA1 associated RING domain 1
chr16_-_81006810 42.93 ENST00000564174.5
ENST00000562713.3
ENST00000570195.5
ENST00000565925.5
ENST00000219400.8
ENST00000565108.5
ENST00000565650.5
ENST00000486645.5
ENST00000630396.1
ENST00000650780.1
C-X9-C motif containing 2
novel protein
chr2_+_180981108 42.91 ENST00000602710.5
ubiquitin conjugating enzyme E2 E3
chr1_+_62437015 42.78 ENST00000339950.5
ubiquitin specific peptidase 1
chr9_+_107284053 42.48 ENST00000416373.6
RAD23 homolog B, nucleotide excision repair protein
chr9_-_35079923 42.48 ENST00000378643.8
ENST00000448890.1
FA complementation group G
chr1_-_8878706 42.47 ENST00000646156.1
enolase 1
chr14_-_22957128 42.39 ENST00000342454.12
ENST00000555986.5
ENST00000554516.5
ENST00000347758.6
ENST00000206474.11
ENST00000555040.5
HAUS augmin like complex subunit 4
chr16_-_74666839 42.14 ENST00000576652.1
ENST00000572337.5
ENST00000571750.5
ENST00000572990.5
ENST00000361070.9
ring finger and WD repeat domain 3
chr10_+_60778490 42.02 ENST00000448257.6
ENST00000614696.4
cyclin dependent kinase 1
chr13_+_113584683 41.70 ENST00000375370.10
transcription factor Dp-1
chr1_-_33036840 41.59 ENST00000548033.5
ENST00000487289.1
ENST00000626911.1
ENST00000673291.1
ENST00000480134.5
ENST00000373449.7
ENST00000672715.1
ENST00000467905.5
ENST00000629371.2
adenylate kinase 2
chr18_+_158513 41.56 ENST00000400266.7
ENST00000580410.5
ENST00000261601.8
ENST00000383589.6
ubiquitin specific peptidase 14
chr15_-_84716063 41.27 ENST00000558217.5
ENST00000558196.1
ENST00000558134.5
SEC11 homolog A, signal peptidase complex subunit
chr11_+_125625967 41.22 ENST00000428830.6
ENST00000278916.8
ENST00000544373.5
ENST00000532669.5
ENST00000527013.6
ENST00000526937.5
ENST00000534685.5
checkpoint kinase 1
chr2_+_197500398 41.08 ENST00000604458.1
HSPE1-MOB4 readthrough
chr9_+_78297143 40.87 ENST00000347159.6
phosphoserine aminotransferase 1
chrX_+_134460138 40.77 ENST00000298556.8
hypoxanthine phosphoribosyltransferase 1
chr20_-_5119945 40.37 ENST00000379143.10
proliferating cell nuclear antigen
chr9_+_78297117 39.99 ENST00000376588.4
phosphoserine aminotransferase 1
chr11_+_64186219 39.99 ENST00000543847.1
stress induced phosphoprotein 1
chr14_-_22957061 39.77 ENST00000557591.5
ENST00000541587.6
ENST00000490506.5
ENST00000554406.1
HAUS augmin like complex subunit 4
chr7_-_26201301 39.36 ENST00000608362.2
ENST00000676749.1
ENST00000677839.1
heterogeneous nuclear ribonucleoprotein A2/B1
chr6_-_85642877 39.29 ENST00000369622.8
synaptotagmin binding cytoplasmic RNA interacting protein
chr16_-_11915878 39.04 ENST00000439887.6
ENST00000434724.7
G1 to S phase transition 1
chr8_+_42391895 39.03 ENST00000521158.5
voltage dependent anion channel 3
chr10_+_93496599 39.02 ENST00000371485.8
centrosomal protein 55
chr17_+_68205453 38.98 ENST00000674770.2
archaelysin family metallopeptidase 2
chr15_-_84716099 38.86 ENST00000560266.5
SEC11 homolog A, signal peptidase complex subunit
chr14_-_22957100 38.79 ENST00000555367.5
HAUS augmin like complex subunit 4
chr7_-_30504744 38.41 ENST00000409390.5
ENST00000409144.5
ENST00000409436.2
ENST00000275428.9
ENST00000005374.10
gamma-glutamylcyclotransferase
chr3_+_129278955 38.38 ENST00000502878.6
ENST00000389735.7
ENST00000509551.5
ENST00000511665.1
5-hydroxymethylcytosine binding, ES cell specific
chr11_+_125626229 38.17 ENST00000532449.6
ENST00000534070.5
checkpoint kinase 1
chr1_-_8878646 38.15 ENST00000643438.1
enolase 1
chr15_-_84716153 37.98 ENST00000455959.7
SEC11 homolog A, signal peptidase complex subunit
chr9_+_104094260 37.90 ENST00000286398.11
ENST00000440179.5
ENST00000374793.8
structural maintenance of chromosomes 2
chr11_+_65919480 37.79 ENST00000527119.5
DR1 associated protein 1
chr3_-_185938006 37.70 ENST00000342294.4
ENST00000453386.7
ENST00000382191.4
transformer 2 beta homolog
chr4_-_24584517 37.69 ENST00000336812.5
DEAH-box helicase 15
chr16_+_53820 37.68 ENST00000293861.8
ENST00000383018.7
ENST00000417493.1
small nuclear ribonucleoprotein U11/U12 subunit 25
chr15_-_84716129 37.62 ENST00000268220.12
SEC11 homolog A, signal peptidase complex subunit
chr12_-_31326111 36.62 ENST00000539409.5
SIN3-HDAC complex associated factor
chr3_+_37861849 36.62 ENST00000273179.10
CTD small phosphatase like
chr17_-_17281232 36.56 ENST00000417352.5
ENST00000268717.10
COP9 signalosome subunit 3
chr12_-_50283472 36.25 ENST00000551691.5
ENST00000394943.7
ENST00000341247.8
LIM domain and actin binding 1
chr14_-_45134454 36.22 ENST00000396062.4
FKBP prolyl isomerase 3
chr16_+_1678271 36.13 ENST00000562684.5
ENST00000561516.5
ENST00000248098.8
ENST00000382711.9
ENST00000566742.5
Jupiter microtubule associated homolog 2
chr12_-_31326142 36.09 ENST00000337682.9
SIN3-HDAC complex associated factor
chr17_+_31937033 36.06 ENST00000580398.1
SUZ12 polycomb repressive complex 2 subunit
chr3_-_182980531 35.67 ENST00000292782.9
ENST00000632685.1
defective in cullin neddylation 1 domain containing 1
chr20_+_3786772 35.67 ENST00000344256.10
ENST00000379598.9
cell division cycle 25B
chr2_-_46941760 35.56 ENST00000444761.6
ENST00000409147.1
multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
chr10_+_123154364 35.36 ENST00000368859.6
ENST00000368865.9
BUB3 mitotic checkpoint protein
chr18_-_36828730 35.16 ENST00000587382.5
tubulin polyglutamylase complex subunit 2
chrX_+_150983350 35.10 ENST00000455596.5
ENST00000448905.6
high mobility group box 3
chr5_+_134758770 35.09 ENST00000628477.2
ENST00000452510.7
ENST00000354283.8
DEAD-box helicase 46
chr2_-_85414039 35.07 ENST00000447219.6
ENST00000409670.5
ENST00000409724.5
capping actin protein, gelsolin like
chr8_-_102864035 34.71 ENST00000683965.1
ENST00000518353.5
antizyme inhibitor 1
chr17_+_82716698 34.59 ENST00000269373.11
ENST00000577128.1
ENST00000573158.5
fructosamine 3 kinase related protein
chrX_+_154762729 34.55 ENST00000620277.4
dyskerin pseudouridine synthase 1
chr5_+_62306228 34.49 ENST00000381103.7
kinesin family member 2A
chr6_+_47477731 34.46 ENST00000359314.5
CD2 associated protein
chr15_-_43824675 34.43 ENST00000267812.4
microfibril associated protein 1
chr19_+_38647679 34.43 ENST00000390009.7
ENST00000589528.1
actinin alpha 4
chr3_+_160399630 34.43 ENST00000465903.5
ENST00000485645.5
ENST00000472991.5
ENST00000467468.5
ENST00000469762.5
ENST00000357388.8
ENST00000489573.5
ENST00000462787.5
ENST00000490207.5
ENST00000485867.5
structural maintenance of chromosomes 4
chr8_-_102864155 34.34 ENST00000682725.1
ENST00000337198.10
ENST00000681985.1
ENST00000684566.1
ENST00000683787.1
ENST00000682014.1
ENST00000682969.1
ENST00000684721.1
ENST00000347770.8
antizyme inhibitor 1
chr2_+_197500371 34.25 ENST00000409468.1
ENST00000233893.10
heat shock protein family E (Hsp10) member 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
85.5 256.5 GO:0006311 meiotic gene conversion(GO:0006311) regulation of reciprocal meiotic recombination(GO:0010520)
76.8 307.0 GO:0019860 uracil metabolic process(GO:0019860)
66.1 198.4 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
49.5 148.5 GO:0075732 viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594)
45.2 587.9 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
39.7 198.5 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
39.0 117.0 GO:0046452 dihydrofolate metabolic process(GO:0046452)
38.1 114.3 GO:0002184 cytoplasmic translational termination(GO:0002184)
36.1 180.5 GO:1904636 response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
35.1 140.5 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
33.4 100.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
32.8 131.2 GO:0090095 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
31.4 94.1 GO:0009786 regulation of asymmetric cell division(GO:0009786)
30.6 91.9 GO:0006172 ADP biosynthetic process(GO:0006172)
28.5 227.9 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
28.5 626.2 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
28.1 168.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
25.3 126.3 GO:0006167 AMP biosynthetic process(GO:0006167)
25.1 226.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
24.9 74.6 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
24.4 73.3 GO:0008614 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819)
24.1 168.4 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
23.8 47.6 GO:0006166 purine ribonucleoside salvage(GO:0006166)
23.0 69.1 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
23.0 298.9 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
22.7 136.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
22.4 89.4 GO:0072423 response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
21.9 87.7 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
21.9 65.6 GO:0090669 telomerase RNA stabilization(GO:0090669)
21.5 64.6 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
20.2 40.4 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
19.9 59.8 GO:1901254 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
19.6 137.4 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
19.5 58.5 GO:0051793 medium-chain fatty acid catabolic process(GO:0051793)
19.3 57.8 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
19.1 57.4 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
18.5 221.5 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
17.4 69.7 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
17.2 34.5 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
16.2 194.9 GO:0090435 protein localization to nuclear envelope(GO:0090435)
16.0 48.1 GO:1904430 negative regulation of t-circle formation(GO:1904430)
15.2 45.7 GO:0032954 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
15.1 45.2 GO:0070512 regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
14.8 59.2 GO:1904045 cellular response to aldosterone(GO:1904045)
14.2 42.6 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
13.8 110.7 GO:0090166 Golgi disassembly(GO:0090166)
13.7 150.6 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
13.5 94.4 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
13.0 77.7 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
12.9 38.7 GO:2000174 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
12.2 73.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
11.9 59.7 GO:1902255 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
11.9 35.7 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
11.8 117.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
11.6 46.6 GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
11.6 473.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
11.2 33.5 GO:0009996 negative regulation of cell fate specification(GO:0009996)
11.1 33.2 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
10.9 283.1 GO:0006270 DNA replication initiation(GO:0006270)
10.8 32.5 GO:0014810 positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014810)
10.7 193.1 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
10.7 85.5 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
10.5 31.6 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
10.4 62.3 GO:0006021 inositol biosynthetic process(GO:0006021)
10.3 61.9 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
10.2 61.3 GO:0015853 adenine transport(GO:0015853)
10.2 51.1 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
10.0 39.9 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
10.0 89.6 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
9.9 49.4 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
9.8 29.4 GO:0071314 cellular response to cocaine(GO:0071314) cellular response to luteinizing hormone stimulus(GO:0071373)
9.7 29.0 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
9.6 57.8 GO:1903679 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
9.6 28.8 GO:0003064 regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
9.3 28.0 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
9.3 37.4 GO:0048627 myoblast development(GO:0048627)
9.2 64.5 GO:0032218 riboflavin transport(GO:0032218)
9.1 27.3 GO:1901874 negative regulation of post-translational protein modification(GO:1901874)
8.9 44.3 GO:0043418 homocysteine catabolic process(GO:0043418)
8.8 52.9 GO:2000371 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
8.8 26.4 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
8.7 26.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
8.7 112.6 GO:0046689 response to mercury ion(GO:0046689)
8.6 77.8 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
8.4 50.7 GO:0003164 His-Purkinje system development(GO:0003164)
8.3 25.0 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
8.3 24.9 GO:0006106 fumarate metabolic process(GO:0006106)
8.1 24.4 GO:2000374 regulation of oxygen metabolic process(GO:2000374)
7.8 47.0 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
7.8 15.6 GO:1901420 negative regulation of response to alcohol(GO:1901420)
7.8 23.3 GO:0051821 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
7.6 114.1 GO:0070986 left/right axis specification(GO:0070986)
7.6 105.9 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
7.5 45.1 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
7.3 66.0 GO:0000710 meiotic mismatch repair(GO:0000710)
7.2 21.7 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
7.1 21.3 GO:1903288 positive regulation of potassium ion import(GO:1903288)
7.1 49.4 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
6.9 41.4 GO:0002943 tRNA dihydrouridine synthesis(GO:0002943)
6.9 34.5 GO:0010266 response to vitamin B1(GO:0010266)
6.9 13.7 GO:0039019 pronephric nephron development(GO:0039019)
6.4 63.7 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
6.3 182.7 GO:0006465 signal peptide processing(GO:0006465)
6.1 258.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
6.0 36.3 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
5.8 23.2 GO:0002501 peptide antigen assembly with MHC protein complex(GO:0002501)
5.8 17.4 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
5.8 63.4 GO:0000733 DNA strand renaturation(GO:0000733)
5.7 17.1 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
5.7 22.7 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
5.6 16.9 GO:0006344 maintenance of chromatin silencing(GO:0006344)
5.6 27.9 GO:0006740 NADPH regeneration(GO:0006740)
5.4 54.4 GO:0006290 pyrimidine dimer repair(GO:0006290)
5.4 37.7 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
5.4 16.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
5.3 186.8 GO:0019985 translesion synthesis(GO:0019985)
5.3 31.7 GO:0006301 postreplication repair(GO:0006301)
5.3 47.5 GO:0001866 NK T cell proliferation(GO:0001866)
5.2 10.4 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
5.1 5.1 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
5.0 40.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
5.0 25.1 GO:0045900 negative regulation of translational elongation(GO:0045900)
5.0 134.1 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
4.9 69.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
4.9 29.7 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
4.9 39.4 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
4.9 98.3 GO:0061157 mRNA destabilization(GO:0061157)
4.9 83.2 GO:0042761 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
4.9 53.6 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
4.9 82.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
4.8 19.3 GO:1903121 rhythmic synaptic transmission(GO:0060024) regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
4.8 19.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
4.8 14.3 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
4.7 42.6 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
4.7 23.5 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
4.7 14.0 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
4.6 9.2 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
4.6 41.0 GO:0010265 SCF complex assembly(GO:0010265)
4.5 40.8 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
4.5 71.9 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
4.4 22.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
4.4 13.3 GO:1990918 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
4.4 43.8 GO:2000252 negative regulation of feeding behavior(GO:2000252)
4.3 25.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
4.2 21.0 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
4.2 12.6 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
4.1 33.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
4.1 16.5 GO:1903803 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
4.0 24.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
4.0 91.0 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
3.9 78.6 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
3.9 74.6 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
3.8 68.9 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
3.8 172.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
3.8 15.3 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
3.8 15.1 GO:0006177 GMP biosynthetic process(GO:0006177)
3.8 26.4 GO:0007144 female meiosis I(GO:0007144)
3.8 26.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
3.8 45.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
3.7 15.0 GO:2001247 positive regulation of phosphatidylcholine biosynthetic process(GO:2001247)
3.7 15.0 GO:0042256 mature ribosome assembly(GO:0042256)
3.7 234.1 GO:0006378 mRNA polyadenylation(GO:0006378) RNA polyadenylation(GO:0043631)
3.6 7.3 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
3.6 32.7 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
3.6 7.2 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
3.6 17.9 GO:0033484 nitric oxide homeostasis(GO:0033484)
3.6 7.2 GO:0002572 pro-T cell differentiation(GO:0002572)
3.6 53.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
3.6 42.7 GO:0015939 pantothenate metabolic process(GO:0015939)
3.5 46.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
3.5 24.7 GO:0008215 spermine metabolic process(GO:0008215)
3.5 24.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
3.4 300.4 GO:0071349 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
3.4 23.7 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
3.3 36.8 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
3.3 249.2 GO:0051439 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436) regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
3.3 9.8 GO:0006059 hexitol metabolic process(GO:0006059)
3.3 13.0 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
3.2 12.9 GO:2000035 regulation of stem cell division(GO:2000035)
3.2 32.1 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
3.1 15.7 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
3.1 9.2 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
3.0 9.1 GO:0015798 myo-inositol transport(GO:0015798)
3.0 12.2 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
3.0 33.4 GO:0070734 histone H3-K27 methylation(GO:0070734)
3.0 5.9 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
2.9 14.7 GO:0016584 nucleosome positioning(GO:0016584)
2.9 29.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
2.9 49.2 GO:0000732 strand displacement(GO:0000732)
2.8 14.2 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
2.8 8.5 GO:0035425 autocrine signaling(GO:0035425)
2.8 19.7 GO:2000561 CD4-positive, alpha-beta T cell proliferation(GO:0035739) regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000561)
2.8 5.6 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
2.8 13.9 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
2.8 11.1 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
2.8 55.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
2.7 60.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
2.7 8.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
2.7 21.4 GO:0000012 single strand break repair(GO:0000012)
2.7 10.7 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
2.6 5.3 GO:0044416 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
2.6 49.6 GO:0061014 positive regulation of mRNA catabolic process(GO:0061014)
2.6 54.6 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
2.6 41.6 GO:0007097 nuclear migration(GO:0007097)
2.6 13.0 GO:0072719 cellular response to cisplatin(GO:0072719)
2.6 15.4 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
2.6 12.8 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
2.5 19.9 GO:0006685 sphingomyelin catabolic process(GO:0006685)
2.5 9.9 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
2.4 9.7 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
2.4 12.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
2.4 26.4 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
2.4 9.5 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) mycotoxin catabolic process(GO:0043387) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound catabolic process(GO:1901377) regulation of glutathione biosynthetic process(GO:1903786) positive regulation of glutathione biosynthetic process(GO:1903788)
2.3 30.4 GO:0090168 Golgi reassembly(GO:0090168)
2.3 16.3 GO:0030421 defecation(GO:0030421)
2.3 120.4 GO:0032392 DNA geometric change(GO:0032392)
2.3 6.9 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
2.3 13.7 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
2.3 29.6 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
2.3 11.4 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
2.3 36.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
2.3 31.8 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
2.3 38.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
2.3 11.3 GO:0006529 asparagine biosynthetic process(GO:0006529)
2.2 8.9 GO:0032025 response to cobalt ion(GO:0032025)
2.2 19.8 GO:0089700 protein kinase D signaling(GO:0089700)
2.2 239.9 GO:0051225 spindle assembly(GO:0051225)
2.2 13.0 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
2.2 13.0 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
2.1 23.6 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
2.1 32.1 GO:0045116 protein neddylation(GO:0045116)
2.1 31.0 GO:0033260 nuclear DNA replication(GO:0033260)
2.1 61.8 GO:0072663 protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
2.1 10.3 GO:2000210 positive regulation of anoikis(GO:2000210)
2.0 24.5 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
2.0 16.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
2.0 6.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
2.0 20.2 GO:0070933 histone H4 deacetylation(GO:0070933)
2.0 212.1 GO:0043488 regulation of mRNA stability(GO:0043488)
2.0 6.0 GO:0061074 regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
2.0 8.0 GO:0007386 compartment pattern specification(GO:0007386)
2.0 20.0 GO:1902177 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
2.0 16.0 GO:0042659 regulation of cell fate specification(GO:0042659)
2.0 6.0 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
2.0 144.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
2.0 3.9 GO:0060743 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) epithelial cell maturation involved in prostate gland development(GO:0060743)
2.0 5.9 GO:0072709 cellular response to sorbitol(GO:0072709) negative regulation of motor neuron apoptotic process(GO:2000672)
1.9 9.7 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
1.9 1.9 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
1.9 9.5 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
1.9 9.5 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
1.9 9.4 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
1.8 9.2 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
1.8 10.9 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
1.8 10.8 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
1.8 16.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
1.8 21.4 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
1.8 8.9 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
1.8 21.3 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
1.8 8.9 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
1.8 7.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
1.8 22.9 GO:0071803 positive regulation of podosome assembly(GO:0071803)
1.8 12.3 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
1.8 3.5 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
1.8 42.0 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
1.7 7.0 GO:0030047 actin modification(GO:0030047)
1.7 60.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
1.7 103.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
1.7 5.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
1.7 5.1 GO:0043311 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001) positive regulation of eosinophil degranulation(GO:0043311) regulation of renin secretion into blood stream(GO:1900133) positive regulation of eosinophil activation(GO:1902568)
1.7 26.8 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
1.6 18.1 GO:0046599 regulation of centriole replication(GO:0046599)
1.6 19.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
1.6 4.8 GO:0040031 snRNA modification(GO:0040031)
1.6 12.7 GO:0040016 embryonic cleavage(GO:0040016)
1.6 3.1 GO:2000850 negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
1.5 13.9 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
1.5 4.5 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
1.5 4.5 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
1.5 10.5 GO:0031017 exocrine pancreas development(GO:0031017)
1.5 13.5 GO:0060235 lens induction in camera-type eye(GO:0060235)
1.5 5.9 GO:1901143 insulin catabolic process(GO:1901143)
1.5 54.3 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
1.5 17.6 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
1.4 11.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.4 7.0 GO:0003415 chondrocyte hypertrophy(GO:0003415)
1.4 45.9 GO:0032467 positive regulation of cytokinesis(GO:0032467)
1.4 18.0 GO:0018206 peptidyl-methionine modification(GO:0018206)
1.4 5.5 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
1.4 73.3 GO:0032781 positive regulation of ATPase activity(GO:0032781)
1.4 27.3 GO:0006337 nucleosome disassembly(GO:0006337)
1.3 20.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
1.3 8.0 GO:0018916 nitrobenzene metabolic process(GO:0018916)
1.3 15.7 GO:0010668 ectodermal cell differentiation(GO:0010668)
1.3 20.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032) regulation of parathyroid hormone secretion(GO:2000828)
1.3 13.9 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.3 6.3 GO:1903715 regulation of aerobic respiration(GO:1903715)
1.2 28.7 GO:0043968 histone H2A acetylation(GO:0043968)
1.2 5.0 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
1.2 16.0 GO:0043174 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097) nucleoside salvage(GO:0043174)
1.2 39.3 GO:0035066 positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758)
1.2 7.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
1.2 10.9 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
1.2 4.9 GO:0080009 mRNA methylation(GO:0080009)
1.2 4.8 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
1.2 60.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
1.2 14.2 GO:0070327 thyroid hormone transport(GO:0070327)
1.1 133.3 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
1.1 46.6 GO:0006458 'de novo' protein folding(GO:0006458)
1.1 4.4 GO:0018199 peptidyl-glutamine modification(GO:0018199)
1.1 9.9 GO:1904424 regulation of GTP binding(GO:1904424)
1.1 14.3 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
1.1 13.2 GO:0006449 regulation of translational termination(GO:0006449)
1.1 1.1 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
1.1 13.9 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
1.1 32.1 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
1.1 43.7 GO:0006513 protein monoubiquitination(GO:0006513)
1.1 4.3 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
1.1 9.5 GO:0035608 protein deglutamylation(GO:0035608)
1.0 18.8 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.0 4.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
1.0 1.0 GO:0072054 renal inner medulla development(GO:0072053) renal outer medulla development(GO:0072054)
1.0 2.0 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
1.0 42.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
1.0 13.6 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
1.0 5.7 GO:0060356 leucine import(GO:0060356)
1.0 1.0 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.9 40.6 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.9 22.6 GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.9 13.7 GO:0043928 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.9 4.5 GO:0007000 nucleolus organization(GO:0007000)
0.9 15.4 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.9 13.6 GO:0006782 protoporphyrinogen IX biosynthetic process(GO:0006782)
0.9 10.8 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.8 61.1 GO:0045454 cell redox homeostasis(GO:0045454)
0.8 15.1 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.8 1.7 GO:0045144 meiotic sister chromatid segregation(GO:0045144)
0.8 17.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.8 20.6 GO:0006491 N-glycan processing(GO:0006491)
0.8 14.8 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.8 3.3 GO:0043335 protein unfolding(GO:0043335)
0.8 30.3 GO:0015804 neutral amino acid transport(GO:0015804)
0.8 2.4 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.8 16.7 GO:0090224 regulation of mitotic spindle organization(GO:0060236) regulation of spindle organization(GO:0090224)
0.8 5.5 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.8 6.3 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.8 22.5 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.8 1.5 GO:0090107 regulation of high-density lipoprotein particle assembly(GO:0090107)
0.7 30.6 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.7 29.5 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.7 2.9 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.7 14.4 GO:0009649 entrainment of circadian clock(GO:0009649)
0.7 6.4 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.7 8.2 GO:0042255 ribosome assembly(GO:0042255)
0.7 6.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.7 1.4 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.7 3.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.7 2.0 GO:0045047 protein targeting to ER(GO:0045047)
0.7 14.9 GO:0007019 microtubule depolymerization(GO:0007019)
0.7 8.8 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.7 1.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.7 14.7 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.7 2.0 GO:0000103 sulfate assimilation(GO:0000103)
0.7 6.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.7 4.6 GO:0009249 protein lipoylation(GO:0009249)
0.6 1.9 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.6 26.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.6 42.5 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.6 1.2 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.6 7.7 GO:0006527 arginine catabolic process(GO:0006527)
0.6 14.1 GO:0051923 sulfation(GO:0051923)
0.6 2.3 GO:1904715 regulation of protein folding(GO:1903332) negative regulation of chaperone-mediated autophagy(GO:1904715)
0.6 1.1 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.6 15.0 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.5 2.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.5 30.1 GO:0031640 killing of cells of other organism(GO:0031640) disruption of cells of other organism(GO:0044364)
0.5 3.7 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.5 4.2 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.5 3.7 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.5 11.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.5 5.1 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.5 3.0 GO:0044415 evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.5 41.5 GO:0090114 COPII-coated vesicle budding(GO:0090114)
0.5 8.9 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.5 4.4 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.5 13.6 GO:0030838 positive regulation of actin filament polymerization(GO:0030838)
0.5 10.9 GO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736)
0.5 4.3 GO:0019054 modulation by virus of host process(GO:0019054)
0.5 14.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.5 36.1 GO:0006364 rRNA processing(GO:0006364)
0.5 5.1 GO:2000269 regulation of fibroblast apoptotic process(GO:2000269) positive regulation of fibroblast apoptotic process(GO:2000271)
0.5 2.7 GO:0008218 bioluminescence(GO:0008218)
0.5 3.2 GO:0015705 iodide transport(GO:0015705)
0.5 29.1 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.5 35.4 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.4 10.8 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.4 10.3 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.4 19.3 GO:0035329 hippo signaling(GO:0035329)
0.4 6.2 GO:0035826 rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.4 8.8 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.4 24.4 GO:0032481 positive regulation of type I interferon production(GO:0032481)
0.4 1.7 GO:0035803 egg coat formation(GO:0035803)
0.4 0.9 GO:0015722 canalicular bile acid transport(GO:0015722)
0.4 3.0 GO:1903416 response to glycoside(GO:1903416)
0.4 10.7 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.4 10.5 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.4 3.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.4 10.9 GO:0007052 mitotic spindle organization(GO:0007052)
0.4 4.5 GO:0017121 phospholipid scrambling(GO:0017121)
0.4 6.9 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.4 0.8 GO:0071888 macrophage apoptotic process(GO:0071888)
0.4 17.7 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.4 0.8 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.4 4.3 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.4 0.4 GO:1903939 regulation of TORC2 signaling(GO:1903939)
0.4 20.0 GO:0001541 ovarian follicle development(GO:0001541)
0.4 5.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.4 2.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.4 27.6 GO:0048278 vesicle docking(GO:0048278)
0.4 3.3 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.4 2.5 GO:0032506 cytokinetic process(GO:0032506)
0.4 2.5 GO:0090527 actin filament reorganization(GO:0090527)
0.4 3.9 GO:0042407 cristae formation(GO:0042407)
0.4 9.5 GO:0007051 spindle organization(GO:0007051)
0.3 2.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.3 2.4 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.3 1.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.3 0.7 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.3 6.5 GO:0006303 double-strand break repair via nonhomologous end joining(GO:0006303)
0.3 9.7 GO:0008210 estrogen metabolic process(GO:0008210)
0.3 8.4 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.3 14.5 GO:0051881 regulation of mitochondrial membrane potential(GO:0051881)
0.3 7.3 GO:0042254 ribosome biogenesis(GO:0042254)
0.3 3.4 GO:0030210 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.3 13.7 GO:0016925 protein sumoylation(GO:0016925)
0.3 1.9 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.3 2.5 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.3 10.2 GO:0014037 Schwann cell differentiation(GO:0014037)
0.3 3.4 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.3 13.3 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.3 7.2 GO:0042491 auditory receptor cell differentiation(GO:0042491)
0.3 5.5 GO:0002828 regulation of type 2 immune response(GO:0002828)
0.3 1.8 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.2 17.7 GO:0030148 sphingolipid biosynthetic process(GO:0030148)
0.2 14.3 GO:0006413 translational initiation(GO:0006413)
0.2 13.4 GO:0008033 tRNA processing(GO:0008033)
0.2 1.3 GO:0098838 methotrexate transport(GO:0051958) reduced folate transmembrane transport(GO:0098838)
0.2 1.6 GO:0030238 male sex determination(GO:0030238)
0.2 1.0 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 1.6 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 2.3 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.2 1.2 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.2 5.2 GO:0019835 cytolysis(GO:0019835)
0.2 16.4 GO:0016126 sterol biosynthetic process(GO:0016126)
0.2 2.9 GO:0030220 platelet formation(GO:0030220)
0.2 4.2 GO:0031529 ruffle organization(GO:0031529)
0.2 4.2 GO:0030224 monocyte differentiation(GO:0030224)
0.2 1.0 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.2 12.2 GO:0006334 nucleosome assembly(GO:0006334)
0.1 7.1 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 4.1 GO:0006672 ceramide metabolic process(GO:0006672)
0.1 15.2 GO:0002576 platelet degranulation(GO:0002576)
0.1 1.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 3.8 GO:0035987 endodermal cell differentiation(GO:0035987)
0.1 0.2 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.1 0.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 1.0 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.1 0.3 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.1 2.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.5 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.1 1.7 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.1 0.9 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 3.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 2.0 GO:0060416 response to growth hormone(GO:0060416)
0.0 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 4.4 GO:0006457 protein folding(GO:0006457)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.4 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.9 GO:0006911 phagocytosis, engulfment(GO:0006911)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
135.1 540.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
64.5 322.5 GO:0032301 MutSalpha complex(GO:0032301)
57.9 753.1 GO:0042555 MCM complex(GO:0042555)
38.1 114.3 GO:0018444 translation release factor complex(GO:0018444)
38.1 228.4 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
35.3 282.7 GO:0000796 condensin complex(GO:0000796)
28.7 114.9 GO:0033186 CAF-1 complex(GO:0033186)
28.6 85.9 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
28.3 113.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
28.1 140.5 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
27.6 137.9 GO:0031436 BRCA1-BARD1 complex(GO:0031436)
26.5 291.9 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
23.2 69.5 GO:0005663 DNA replication factor C complex(GO:0005663)
21.9 131.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
21.7 86.8 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
21.1 63.4 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
21.0 83.9 GO:0000811 GINS complex(GO:0000811)
20.3 182.7 GO:0005787 signal peptidase complex(GO:0005787)
20.3 142.0 GO:0034715 pICln-Sm protein complex(GO:0034715)
20.2 60.6 GO:0031261 DNA replication preinitiation complex(GO:0031261)
19.9 59.8 GO:1902737 dendritic filopodium(GO:1902737)
18.8 150.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
18.3 91.6 GO:0016589 NURF complex(GO:0016589)
18.1 289.6 GO:0045120 pronucleus(GO:0045120)
17.0 67.9 GO:0031510 SUMO activating enzyme complex(GO:0031510)
16.4 279.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
15.0 75.0 GO:0031523 Myb complex(GO:0031523)
15.0 164.6 GO:0005638 lamin filament(GO:0005638)
14.1 126.5 GO:0042382 paraspeckles(GO:0042382)
10.9 76.2 GO:0001739 sex chromatin(GO:0001739)
10.7 203.6 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
10.7 74.8 GO:0030893 meiotic cohesin complex(GO:0030893)
10.5 73.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
10.3 51.6 GO:0043625 delta DNA polymerase complex(GO:0043625)
10.1 50.7 GO:0043564 Ku70:Ku80 complex(GO:0043564)
9.6 105.5 GO:0042575 DNA polymerase complex(GO:0042575)
9.4 65.6 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
9.2 101.5 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
9.1 18.1 GO:0044094 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
8.9 80.4 GO:0036449 microtubule minus-end(GO:0036449)
8.7 43.6 GO:0000408 EKC/KEOPS complex(GO:0000408)
8.7 113.1 GO:0005688 U6 snRNP(GO:0005688)
8.1 40.5 GO:0089701 U2AF(GO:0089701)
8.1 32.3 GO:0071942 XPC complex(GO:0071942)
7.9 94.9 GO:0090543 Flemming body(GO:0090543)
7.8 39.0 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
7.5 75.2 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
7.2 36.2 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
6.8 34.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
6.7 73.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
6.2 118.4 GO:0005641 nuclear envelope lumen(GO:0005641)
6.0 54.1 GO:0070652 HAUS complex(GO:0070652)
5.9 23.6 GO:0030915 Smc5-Smc6 complex(GO:0030915)
5.7 17.1 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
5.6 16.7 GO:0031262 Ndc80 complex(GO:0031262)
5.6 22.2 GO:0035363 histone locus body(GO:0035363)
5.5 71.9 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
5.4 37.5 GO:1990111 spermatoproteasome complex(GO:1990111)
5.1 40.8 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
5.1 76.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
4.9 39.2 GO:0031931 TORC1 complex(GO:0031931)
4.9 9.7 GO:0000805 X chromosome(GO:0000805)
4.8 33.8 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
4.8 9.6 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
4.8 33.6 GO:0030121 AP-1 adaptor complex(GO:0030121)
4.7 23.7 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
4.7 23.7 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
4.7 32.9 GO:0005956 protein kinase CK2 complex(GO:0005956)
4.7 32.7 GO:0032021 NELF complex(GO:0032021)
4.6 105.4 GO:0030992 intraciliary transport particle B(GO:0030992)
4.5 72.4 GO:0005686 U2 snRNP(GO:0005686)
4.4 40.0 GO:0072546 ER membrane protein complex(GO:0072546)
4.4 22.2 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
4.4 30.9 GO:0034719 SMN-Sm protein complex(GO:0034719)
4.4 52.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
4.3 13.0 GO:0071821 FANCM-MHF complex(GO:0071821)
4.2 122.9 GO:0035145 exon-exon junction complex(GO:0035145)
4.1 114.6 GO:0002080 acrosomal membrane(GO:0002080)
4.0 11.9 GO:0044611 nuclear pore inner ring(GO:0044611)
4.0 15.8 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
4.0 27.7 GO:0000235 astral microtubule(GO:0000235) aster(GO:0005818)
3.9 19.7 GO:0033503 HULC complex(GO:0033503)
3.9 100.9 GO:0043596 nuclear replication fork(GO:0043596)
3.8 38.3 GO:0032059 bleb(GO:0032059)
3.8 49.4 GO:0002199 zona pellucida receptor complex(GO:0002199)
3.7 11.2 GO:0033593 BRCA2-MAGE-D1 complex(GO:0033593)
3.7 171.5 GO:0090544 BAF-type complex(GO:0090544)
3.7 40.4 GO:0000178 exosome (RNase complex)(GO:0000178)
3.6 46.6 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
3.6 25.0 GO:0000812 Swr1 complex(GO:0000812)
3.6 28.6 GO:0061700 GATOR2 complex(GO:0061700)
3.6 35.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
3.6 120.8 GO:0000421 autophagosome membrane(GO:0000421)
3.5 24.4 GO:0008290 F-actin capping protein complex(GO:0008290)
3.4 99.8 GO:0030532 small nuclear ribonucleoprotein complex(GO:0030532)
3.4 13.7 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
3.4 311.5 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
3.4 40.3 GO:0030008 TRAPP complex(GO:0030008)
3.3 29.4 GO:0000938 GARP complex(GO:0000938)
3.1 6.1 GO:1990075 periciliary membrane compartment(GO:1990075)
3.1 67.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
2.9 182.7 GO:0005876 spindle microtubule(GO:0005876)
2.8 31.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
2.8 19.7 GO:0042587 glycogen granule(GO:0042587)
2.8 22.3 GO:0070187 telosome(GO:0070187)
2.8 218.9 GO:0000502 proteasome complex(GO:0000502)
2.7 38.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
2.7 29.3 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
2.6 28.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
2.5 101.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
2.5 22.4 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
2.5 14.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
2.4 7.3 GO:0035370 UBC13-UEV1A complex(GO:0035370)
2.4 9.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
2.4 14.4 GO:1990357 terminal web(GO:1990357)
2.3 72.4 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
2.3 46.5 GO:0005885 Arp2/3 protein complex(GO:0005885)
2.3 52.0 GO:0046930 pore complex(GO:0046930)
2.2 28.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
2.2 230.1 GO:0031970 organelle envelope lumen(GO:0031970)
2.2 158.0 GO:0005637 nuclear inner membrane(GO:0005637)
2.2 38.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
2.1 19.3 GO:0035749 myelin sheath adaxonal region(GO:0035749)
2.1 64.2 GO:0030686 90S preribosome(GO:0030686)
2.0 27.8 GO:0000124 SAGA complex(GO:0000124)
2.0 35.3 GO:0051233 spindle midzone(GO:0051233)
1.9 44.4 GO:0005680 anaphase-promoting complex(GO:0005680)
1.9 51.9 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
1.8 16.3 GO:0044327 dendritic spine head(GO:0044327)
1.8 21.6 GO:0016602 CCAAT-binding factor complex(GO:0016602)
1.8 30.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
1.7 7.0 GO:0005846 nuclear cap binding complex(GO:0005846)
1.7 34.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
1.7 63.5 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
1.7 18.8 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
1.7 171.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
1.7 97.9 GO:0045171 intercellular bridge(GO:0045171)
1.7 9.9 GO:0032389 MutLalpha complex(GO:0032389)
1.7 9.9 GO:0000322 storage vacuole(GO:0000322)
1.6 73.3 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
1.6 24.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
1.6 9.6 GO:0034709 methylosome(GO:0034709)
1.6 9.5 GO:0061617 MICOS complex(GO:0061617)
1.6 14.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.5 4.5 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
1.5 13.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
1.5 8.9 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
1.4 228.5 GO:0000793 condensed chromosome(GO:0000793)
1.4 32.6 GO:0005868 cytoplasmic dynein complex(GO:0005868)
1.4 4.1 GO:0001652 granular component(GO:0001652)
1.4 13.8 GO:0033276 transcription factor TFTC complex(GO:0033276)
1.4 101.4 GO:0070469 respiratory chain(GO:0070469)
1.3 13.4 GO:0000439 core TFIIH complex(GO:0000439)
1.3 38.9 GO:0030057 desmosome(GO:0030057)
1.3 19.9 GO:0035861 site of double-strand break(GO:0035861)
1.3 15.6 GO:0070938 contractile ring(GO:0070938)
1.2 18.7 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
1.2 13.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
1.2 14.6 GO:0005915 zonula adherens(GO:0005915)
1.2 63.1 GO:0031430 M band(GO:0031430)
1.2 171.5 GO:0034399 nuclear periphery(GO:0034399)
1.1 8.0 GO:0030891 VCB complex(GO:0030891)
1.1 12.0 GO:0033202 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
1.1 4.3 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
1.1 6.4 GO:0044754 autolysosome(GO:0044754)
1.0 3.1 GO:0031080 nuclear pore outer ring(GO:0031080)
1.0 16.7 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
1.0 29.8 GO:0031143 pseudopodium(GO:0031143)
1.0 34.6 GO:0015030 Cajal body(GO:0015030)
1.0 4.9 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
1.0 2.9 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.9 39.2 GO:0008180 COP9 signalosome(GO:0008180)
0.8 5.9 GO:0010369 chromocenter(GO:0010369)
0.8 85.3 GO:0016605 PML body(GO:0016605)
0.8 2.5 GO:0031010 ISWI-type complex(GO:0031010)
0.8 2.5 GO:0061574 ASAP complex(GO:0061574)
0.8 23.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.8 7.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.8 33.6 GO:0035577 azurophil granule membrane(GO:0035577)
0.8 2.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.8 14.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.8 39.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.8 7.8 GO:0097433 dense body(GO:0097433)
0.7 23.2 GO:0005871 kinesin complex(GO:0005871)
0.7 15.7 GO:0030056 hemidesmosome(GO:0030056)
0.7 81.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.7 53.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.7 15.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.7 244.1 GO:0016607 nuclear speck(GO:0016607)
0.7 45.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.7 2.8 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.7 2.1 GO:0005606 laminin-1 complex(GO:0005606)
0.7 165.8 GO:0019866 organelle inner membrane(GO:0019866)
0.7 55.8 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.7 8.6 GO:0031209 SCAR complex(GO:0031209)
0.6 25.2 GO:0008023 transcription elongation factor complex(GO:0008023)
0.6 3.0 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.6 18.4 GO:0031941 filamentous actin(GO:0031941)
0.6 3.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.6 14.8 GO:0031264 death-inducing signaling complex(GO:0031264)
0.5 8.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.5 8.6 GO:0097470 ribbon synapse(GO:0097470)
0.5 124.1 GO:0043292 contractile fiber(GO:0043292)
0.5 4.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.5 6.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.5 9.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.5 3.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.4 11.8 GO:0032420 stereocilium(GO:0032420)
0.4 1.3 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.4 1.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.4 3.4 GO:0005869 dynactin complex(GO:0005869)
0.4 4.9 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.4 148.7 GO:0005635 nuclear envelope(GO:0005635)
0.4 40.7 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.4 50.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.4 30.1 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.4 47.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.3 5.5 GO:0031089 platelet dense granule lumen(GO:0031089) platelet dense granule(GO:0042827)
0.3 17.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 1.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 0.8 GO:0036021 endolysosome lumen(GO:0036021)
0.3 6.2 GO:0002102 podosome(GO:0002102)
0.3 6.4 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2 9.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 8.4 GO:0005840 ribosome(GO:0005840)
0.2 2.1 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 8.4 GO:0072686 mitotic spindle(GO:0072686)
0.2 5.9 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 3.6 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.2 1.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.9 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 17.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.1 0.7 GO:0070822 Sin3-type complex(GO:0070822)
0.1 2.2 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 1.0 GO:0061689 tricellular tight junction(GO:0061689)
0.1 2.6 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 0.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 3.1 GO:0005811 lipid particle(GO:0005811)
0.0 4.3 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
135.1 540.5 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
64.5 322.5 GO:0032143 single thymine insertion binding(GO:0032143)
57.6 230.5 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
56.1 224.3 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
53.9 161.6 GO:0004638 phosphoribosylaminoimidazole carboxylase activity(GO:0004638) phosphoribosylaminoimidazolesuccinocarboxamide synthase activity(GO:0004639)
44.9 134.8 GO:0003896 DNA primase activity(GO:0003896)
38.5 500.9 GO:1990825 sequence-specific mRNA binding(GO:1990825)
33.6 100.7 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
32.5 227.7 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
22.9 137.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
22.4 313.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
21.9 87.7 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
19.6 156.9 GO:0050733 RS domain binding(GO:0050733)
19.5 58.5 GO:0070991 medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
19.3 57.8 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
19.0 114.3 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
18.9 113.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
18.8 150.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
18.3 54.8 GO:0004170 dUTP diphosphatase activity(GO:0004170)
17.5 105.0 GO:0036033 mediator complex binding(GO:0036033)
16.5 82.6 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
14.7 176.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
14.4 57.4 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
14.2 71.1 GO:1990446 U1 snRNP binding(GO:1990446)
13.5 40.4 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
13.3 693.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
12.8 12.8 GO:0004137 deoxycytidine kinase activity(GO:0004137)
11.9 35.7 GO:0098808 mRNA cap binding(GO:0098808)
11.3 33.9 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
11.2 44.7 GO:0002060 purine nucleobase binding(GO:0002060)
11.1 44.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
11.0 76.8 GO:0004797 thymidine kinase activity(GO:0004797)
10.9 87.3 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
10.5 20.9 GO:0044547 DNA topoisomerase binding(GO:0044547)
10.4 41.6 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
9.9 69.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
9.9 167.7 GO:0035173 histone kinase activity(GO:0035173)
9.4 65.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
9.3 102.8 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
9.2 64.5 GO:0032217 riboflavin transporter activity(GO:0032217)
9.1 54.6 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
8.7 260.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
8.4 25.3 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
8.3 50.0 GO:0030620 U2 snRNA binding(GO:0030620)
8.3 33.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
7.7 30.9 GO:0004001 adenosine kinase activity(GO:0004001)
7.7 61.3 GO:0015288 porin activity(GO:0015288)
7.7 61.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
7.6 45.6 GO:0047134 protein-disulfide reductase activity(GO:0047134)
7.4 52.0 GO:0050815 phosphoserine binding(GO:0050815)
7.4 22.1 GO:0016420 [acyl-carrier-protein] S-malonyltransferase activity(GO:0004314) S-malonyltransferase activity(GO:0016419) malonyltransferase activity(GO:0016420)
7.2 57.8 GO:0036310 annealing helicase activity(GO:0036310)
7.2 72.0 GO:0042731 PH domain binding(GO:0042731)
7.2 28.8 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
6.9 41.4 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
6.8 225.3 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
6.8 67.9 GO:0044388 small protein activating enzyme binding(GO:0044388)
6.7 40.1 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
6.5 26.2 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
6.5 32.5 GO:0050610 glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
6.4 19.3 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717)
6.3 25.4 GO:0004074 biliverdin reductase activity(GO:0004074)
6.3 50.7 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
6.0 59.7 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
5.9 152.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
5.8 17.5 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
5.7 22.7 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
5.6 219.3 GO:0031492 nucleosomal DNA binding(GO:0031492)
5.6 78.1 GO:0004017 adenylate kinase activity(GO:0004017)
5.5 87.3 GO:0003678 DNA helicase activity(GO:0003678)
5.4 254.8 GO:0061650 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
5.4 37.8 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
5.4 144.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
5.4 26.8 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
5.3 63.9 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
5.3 52.8 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
5.2 15.7 GO:0015140 malate transmembrane transporter activity(GO:0015140)
5.0 20.0 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
5.0 14.9 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
5.0 74.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
4.9 64.3 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
4.9 34.5 GO:0005497 androgen binding(GO:0005497)
4.9 14.6 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
4.8 19.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
4.7 9.5 GO:0070990 snRNP binding(GO:0070990)
4.7 14.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
4.7 107.6 GO:0005537 mannose binding(GO:0005537)
4.5 85.7 GO:0000400 four-way junction DNA binding(GO:0000400)
4.5 35.9 GO:0030621 U4 snRNA binding(GO:0030621)
4.4 111.1 GO:0032794 GTPase activating protein binding(GO:0032794)
4.4 26.4 GO:0061665 SUMO ligase activity(GO:0061665)
4.3 129.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
4.2 25.1 GO:0005047 signal recognition particle binding(GO:0005047)
4.2 20.8 GO:0004427 inorganic diphosphatase activity(GO:0004427)
4.1 81.9 GO:0031491 nucleosome binding(GO:0031491)
4.1 20.3 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
4.0 122.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
3.9 50.9 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
3.8 23.0 GO:0004594 pantothenate kinase activity(GO:0004594)
3.8 30.3 GO:0001055 RNA polymerase II activity(GO:0001055)
3.8 15.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
3.7 100.4 GO:0043274 phospholipase binding(GO:0043274)
3.7 14.8 GO:0043515 kinetochore binding(GO:0043515)
3.6 57.4 GO:0017128 phospholipid scramblase activity(GO:0017128)
3.6 17.9 GO:0034597 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
3.6 14.3 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
3.4 13.7 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
3.3 23.2 GO:0001849 complement component C1q binding(GO:0001849)
3.3 36.3 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
3.3 13.0 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
3.2 67.5 GO:0001056 RNA polymerase III activity(GO:0001056)
3.2 9.6 GO:0034511 U3 snoRNA binding(GO:0034511)
3.1 34.5 GO:0039706 co-receptor binding(GO:0039706)
3.1 25.1 GO:0046790 virion binding(GO:0046790)
3.1 43.7 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
3.1 61.7 GO:0070064 proline-rich region binding(GO:0070064)
3.1 64.6 GO:0004532 exoribonuclease activity(GO:0004532)
3.1 70.7 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
3.0 14.9 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
2.9 53.1 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
2.9 114.7 GO:0070717 poly-purine tract binding(GO:0070717)
2.9 79.0 GO:0008483 transaminase activity(GO:0008483)
2.9 20.5 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
2.9 5.8 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
2.9 66.3 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
2.8 30.7 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
2.7 30.2 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
2.6 15.8 GO:0030957 Tat protein binding(GO:0030957)
2.6 10.5 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
2.5 28.0 GO:0016832 aldehyde-lyase activity(GO:0016832)
2.4 389.1 GO:0042393 histone binding(GO:0042393)
2.4 9.8 GO:0004335 galactokinase activity(GO:0004335)
2.3 11.7 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
2.3 51.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
2.3 111.3 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
2.3 13.9 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
2.3 6.9 GO:0055077 gap junction hemi-channel activity(GO:0055077)
2.2 19.9 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
2.2 13.2 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
2.2 6.6 GO:0016154 thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154)
2.2 70.0 GO:0046966 thyroid hormone receptor binding(GO:0046966)
2.2 6.5 GO:0055100 adiponectin binding(GO:0055100)
2.2 15.1 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
2.2 47.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
2.1 59.8 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
2.1 16.5 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
2.0 12.2 GO:0004645 phosphorylase activity(GO:0004645)
2.0 14.1 GO:0000150 recombinase activity(GO:0000150)
2.0 110.3 GO:0031593 polyubiquitin binding(GO:0031593)
2.0 41.9 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
2.0 95.3 GO:0050681 androgen receptor binding(GO:0050681)
2.0 5.9 GO:0031626 beta-endorphin binding(GO:0031626)
2.0 175.4 GO:0004386 helicase activity(GO:0004386)
2.0 15.7 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
2.0 54.9 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
1.9 11.5 GO:0000182 rDNA binding(GO:0000182)
1.9 53.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.9 24.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
1.9 129.9 GO:0070888 E-box binding(GO:0070888)
1.8 106.1 GO:0003727 single-stranded RNA binding(GO:0003727)
1.8 132.4 GO:0043130 ubiquitin binding(GO:0043130)
1.8 32.1 GO:0097602 cullin family protein binding(GO:0097602)
1.8 14.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
1.8 5.3 GO:0098847 sequence-specific single stranded DNA binding(GO:0098847)
1.7 10.4 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
1.7 23.7 GO:0032050 clathrin heavy chain binding(GO:0032050)
1.7 10.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
1.7 13.4 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.7 5.0 GO:0004566 beta-glucuronidase activity(GO:0004566)
1.6 44.3 GO:0003746 translation elongation factor activity(GO:0003746)
1.6 6.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
1.6 17.5 GO:0019869 chloride channel inhibitor activity(GO:0019869)
1.6 7.9 GO:0047280 nicotinamide phosphoribosyltransferase activity(GO:0047280)
1.6 9.4 GO:0019237 centromeric DNA binding(GO:0019237)
1.6 4.7 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
1.5 306.8 GO:0003735 structural constituent of ribosome(GO:0003735)
1.5 4.6 GO:0016979 lipoate-protein ligase activity(GO:0016979)
1.5 13.4 GO:0043008 ATP-dependent protein binding(GO:0043008)
1.5 28.3 GO:0004697 protein kinase C activity(GO:0004697)
1.4 12.9 GO:0046527 glucosyltransferase activity(GO:0046527)
1.4 15.7 GO:0038132 neuregulin binding(GO:0038132)
1.4 4.3 GO:1904928 coreceptor activity involved in canonical Wnt signaling pathway(GO:1904928)
1.4 5.6 GO:0016972 flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
1.4 47.9 GO:0031369 translation initiation factor binding(GO:0031369)
1.4 67.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.4 4.2 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
1.4 7.0 GO:0061133 endopeptidase activator activity(GO:0061133)
1.4 66.1 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
1.4 59.8 GO:0030544 Hsp70 protein binding(GO:0030544)
1.4 10.8 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
1.3 34.8 GO:0051879 Hsp90 protein binding(GO:0051879)
1.3 6.6 GO:1990460 leptin receptor binding(GO:1990460)
1.3 15.4 GO:0031386 protein tag(GO:0031386)
1.2 68.8 GO:0031072 heat shock protein binding(GO:0031072)
1.2 39.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
1.2 7.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
1.2 16.6 GO:0000339 RNA cap binding(GO:0000339)
1.2 16.5 GO:0048156 tau protein binding(GO:0048156)
1.2 51.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
1.1 11.2 GO:0001727 lipid kinase activity(GO:0001727)
1.1 59.5 GO:0003725 double-stranded RNA binding(GO:0003725)
1.1 5.5 GO:0005134 interleukin-2 receptor binding(GO:0005134)
1.1 5.4 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
1.1 5.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
1.0 13.6 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
1.0 30.3 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
1.0 18.5 GO:0042162 telomeric DNA binding(GO:0042162)
1.0 75.0 GO:0003697 single-stranded DNA binding(GO:0003697)
1.0 8.0 GO:0031996 thioesterase binding(GO:0031996)
1.0 7.0 GO:0016403 dimethylargininase activity(GO:0016403)
0.9 4.7 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.9 25.5 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.9 71.2 GO:0051082 unfolded protein binding(GO:0051082)
0.9 3.7 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.9 3.7 GO:0032810 sterol response element binding(GO:0032810)
0.9 51.3 GO:0004180 carboxypeptidase activity(GO:0004180)
0.9 9.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.9 24.2 GO:0005521 lamin binding(GO:0005521)
0.9 11.1 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.8 5.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.8 13.5 GO:0070513 death domain binding(GO:0070513)
0.8 7.6 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.8 157.1 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.8 10.1 GO:0070628 proteasome binding(GO:0070628)
0.8 63.2 GO:0003777 microtubule motor activity(GO:0003777)
0.8 5.0 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.8 17.5 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.8 2.4 GO:0035529 phosphodiesterase I activity(GO:0004528) NADH pyrophosphatase activity(GO:0035529)
0.8 6.4 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.8 3.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.8 13.6 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.8 31.9 GO:0042169 SH2 domain binding(GO:0042169)
0.8 7.8 GO:0034594 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
0.8 40.3 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.8 17.0 GO:0017166 vinculin binding(GO:0017166)
0.8 1.5 GO:0030226 apolipoprotein receptor activity(GO:0030226)
0.7 4.5 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.7 24.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.7 5.7 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.7 2.1 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.7 7.5 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.7 28.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.7 18.8 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.7 17.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.7 249.8 GO:0045296 cadherin binding(GO:0045296)
0.7 2.0 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.6 7.5 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.6 15.0 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.6 22.5 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.6 7.3 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.5 46.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.5 6.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.5 41.7 GO:0008565 protein transporter activity(GO:0008565)
0.5 20.3 GO:0015485 cholesterol binding(GO:0015485)
0.5 4.5 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.5 4.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075) aryl hydrocarbon receptor binding(GO:0017162)
0.4 5.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.4 27.9 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.4 2.0 GO:0008420 CTD phosphatase activity(GO:0008420)
0.4 4.9 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.4 1.6 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.4 41.3 GO:0035326 enhancer binding(GO:0035326)
0.4 13.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.4 64.4 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.4 6.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.4 3.9 GO:0045159 myosin II binding(GO:0045159)
0.4 9.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.3 4.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.3 4.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.3 4.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.3 29.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.3 5.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.3 2.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.3 1.9 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.3 13.0 GO:0008009 chemokine activity(GO:0008009)
0.3 12.5 GO:0005504 fatty acid binding(GO:0005504)
0.2 0.7 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.2 2.1 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.2 3.4 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.2 13.5 GO:0016836 hydro-lyase activity(GO:0016836)
0.2 2.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.2 1.3 GO:0015350 reduced folate carrier activity(GO:0008518) methotrexate transporter activity(GO:0015350)
0.2 3.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 4.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 3.3 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.2 10.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 1.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 1.0 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.2 1.8 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 4.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 55.2 GO:0008236 serine-type peptidase activity(GO:0008236)
0.2 1.7 GO:0032190 acrosin binding(GO:0032190)
0.2 1.6 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.2 8.4 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.2 3.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 21.0 GO:0051015 actin filament binding(GO:0051015)
0.2 1.4 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 0.9 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.9 GO:0043422 protein kinase B binding(GO:0043422)
0.1 2.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 0.8 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250) ER retention sequence binding(GO:0046923)
0.1 3.2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 8.8 GO:0051117 ATPase binding(GO:0051117)
0.1 2.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 1.2 GO:0048018 receptor agonist activity(GO:0048018)
0.1 0.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 84.0 GO:0003723 RNA binding(GO:0003723)
0.1 0.9 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.1 0.5 GO:0045499 chemorepellent activity(GO:0045499)
0.1 1.0 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 3.5 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 1.6 GO:0008374 O-acyltransferase activity(GO:0008374)
0.1 5.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.7 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 3.7 GO:0008237 metallopeptidase activity(GO:0008237)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.3 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.7 GO:0043621 protein self-association(GO:0043621)
0.0 0.2 GO:0051428 peptide hormone receptor binding(GO:0051428)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
15.9 126.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
15.6 1859.2 PID E2F PATHWAY E2F transcription factor network
15.3 306.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
10.2 142.7 PID FANCONI PATHWAY Fanconi anemia pathway
10.2 568.6 PID ATR PATHWAY ATR signaling pathway
6.0 24.2 PID TRAIL PATHWAY TRAIL signaling pathway
5.4 189.7 PID BARD1 PATHWAY BARD1 signaling events
5.0 129.3 PID ATM PATHWAY ATM pathway
4.8 190.9 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
4.3 4.3 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
4.0 230.4 PID AURORA B PATHWAY Aurora B signaling
3.1 12.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
2.9 46.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
2.7 54.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
2.7 94.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
2.4 460.5 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
2.4 37.9 PID MYC PATHWAY C-MYC pathway
2.3 109.4 PID PLK1 PATHWAY PLK1 signaling events
2.3 152.4 PID TELOMERASE PATHWAY Regulation of Telomerase
2.3 237.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
2.2 21.7 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
2.1 191.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
2.0 39.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
1.9 1.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
1.7 76.7 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
1.6 172.4 PID CMYB PATHWAY C-MYB transcription factor network
1.6 98.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
1.5 39.9 WNT SIGNALING Genes related to Wnt-mediated signal transduction
1.5 52.9 PID VEGFR1 PATHWAY VEGFR1 specific signals
1.5 54.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
1.3 14.6 ST JAK STAT PATHWAY Jak-STAT Pathway
1.3 17.8 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
1.2 15.7 PID IL2 1PATHWAY IL2-mediated signaling events
1.1 7.8 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
1.0 64.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
1.0 40.4 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.9 31.0 PID ALK1 PATHWAY ALK1 signaling events
0.9 4.5 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.8 22.9 PID IL3 PATHWAY IL3-mediated signaling events
0.8 40.4 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.8 23.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.7 4.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.7 8.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.7 14.5 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.6 27.8 PID LKB1 PATHWAY LKB1 signaling events
0.6 34.7 PID P73PATHWAY p73 transcription factor network
0.5 8.0 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.5 20.3 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.5 8.6 PID RAC1 PATHWAY RAC1 signaling pathway
0.5 12.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.5 19.6 PID ARF6 PATHWAY Arf6 signaling events
0.4 14.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.4 6.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.4 12.5 PID TGFBR PATHWAY TGF-beta receptor signaling
0.4 12.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.3 5.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.3 10.8 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.2 18.0 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.2 1.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.2 2.2 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.1 6.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 3.8 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 2.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 4.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 4.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 2.6 PID FAS PATHWAY FAS (CD95) signaling pathway
0.1 3.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 4.5 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.3 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.1 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.5 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.7 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.5 PID CDC42 PATHWAY CDC42 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
59.4 890.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
32.5 974.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
29.3 381.1 REACTOME POL SWITCHING Genes involved in Polymerase switching
21.9 328.5 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
15.9 238.7 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
15.0 135.1 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
13.5 202.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
12.8 12.8 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
12.0 36.0 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
9.2 202.1 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
8.9 293.8 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
8.5 161.9 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
8.5 253.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
8.2 163.4 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
8.1 242.6 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
8.0 246.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
7.3 160.9 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
7.1 99.5 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
6.9 69.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
5.8 86.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
5.6 860.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
5.0 75.6 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
4.7 109.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
4.7 52.0 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
4.6 60.1 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
4.6 445.3 REACTOME S PHASE Genes involved in S Phase
4.4 31.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
4.3 46.8 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
4.1 143.5 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
4.0 132.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
3.7 191.2 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
3.6 89.3 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
3.5 59.9 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
3.5 97.2 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
3.4 58.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
3.4 60.4 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
3.3 97.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
3.2 31.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
3.1 6.2 REACTOME CELL CELL COMMUNICATION Genes involved in Cell-Cell communication
3.1 15.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
3.0 89.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
2.9 130.4 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
2.8 22.3 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
2.8 96.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
2.8 22.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
2.7 96.6 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
2.7 99.2 REACTOME MEIOSIS Genes involved in Meiosis
2.7 40.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
2.7 42.7 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
2.6 28.7 REACTOME CHROMOSOME MAINTENANCE Genes involved in Chromosome Maintenance
2.6 53.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
2.5 42.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
2.4 161.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
2.4 76.7 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
2.4 367.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
2.3 78.9 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
2.3 498.1 REACTOME TRANSLATION Genes involved in Translation
2.1 45.1 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
2.0 28.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
1.9 38.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
1.8 33.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
1.8 142.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
1.8 50.1 REACTOME KINESINS Genes involved in Kinesins
1.7 97.4 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
1.5 19.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
1.5 43.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
1.4 31.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
1.4 23.8 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
1.3 46.4 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
1.3 45.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
1.2 29.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
1.1 32.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
1.1 54.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
1.0 29.8 REACTOME G1 PHASE Genes involved in G1 Phase
1.0 8.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
1.0 8.8 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
1.0 12.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.9 14.1 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.9 47.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.8 100.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.8 6.7 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.7 12.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.7 1.4 REACTOME PI3K CASCADE Genes involved in PI3K Cascade
0.7 20.0 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.6 11.0 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.6 33.0 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.6 1.2 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.5 9.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.5 16.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.5 6.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.5 17.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.5 14.1 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.4 6.7 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.4 10.8 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.4 24.0 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.4 19.0 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.4 2.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.3 14.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.3 5.9 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.3 2.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.3 2.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.2 16.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.2 2.1 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.2 6.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2 5.5 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.2 0.7 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 2.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.2 4.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.2 4.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 4.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 2.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 0.9 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 3.9 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.1 2.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 0.9 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.1 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 2.5 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.1 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 2.2 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression