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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for EBF1

Z-value: 12.22

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Transcription factors associated with EBF1

Gene Symbol Gene ID Gene Info
ENSG00000164330.17 EBF1

Activity profile of EBF1 motif

Sorted Z-values of EBF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EBF1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_156248084 67.12 ENST00000652405.1
ENST00000335852.6
ENST00000540423.5
ENST00000612424.4
ENST00000613336.4
ENST00000623241.3
progestin and adipoQ receptor family member 6
chr1_-_156248013 60.25 ENST00000368270.2
progestin and adipoQ receptor family member 6
chr11_-_111910888 58.67 ENST00000525823.1
ENST00000528961.6
crystallin alpha B
chr1_-_156248038 58.28 ENST00000470198.5
ENST00000292291.10
ENST00000356983.7
progestin and adipoQ receptor family member 6
chr19_+_49119531 57.98 ENST00000334186.9
PTPRF interacting protein alpha 3
chr11_-_111910790 57.68 ENST00000533280.6
crystallin alpha B
chr11_-_111910830 55.02 ENST00000526167.5
ENST00000651650.1
crystallin alpha B
chr17_+_39927724 51.39 ENST00000377924.6
ENST00000578802.1
ENST00000578478.1
ENST00000582263.1
leucine rich repeat containing 3C
novel transcript
chr14_-_20802836 50.31 ENST00000397967.5
ENST00000555698.5
ENST00000397970.4
ENST00000340900.3
ribonuclease A family member 1, pancreatic
chr11_-_111923722 50.14 ENST00000527950.5
crystallin alpha B
chr2_-_176002250 47.41 ENST00000392540.6
ENST00000272748.9
ENST00000409660.5
ENST00000544803.5
lunapark, ER junction formation factor
chr19_-_36528232 46.38 ENST00000592282.1
ENST00000523638.6
zinc finger protein 260
chr22_+_22887780 43.60 ENST00000532223.2
ENST00000526893.6
ENST00000531372.1
immunoglobulin lambda like polypeptide 5
chr13_-_30307539 42.60 ENST00000380615.8
katanin catalytic subunit A1 like 1
chr5_-_150412743 42.03 ENST00000353334.11
ENST00000009530.12
ENST00000377795.7
CD74 molecule
chr14_+_22515623 41.34 ENST00000390509.1
T cell receptor alpha joining 28
chr19_-_48634526 41.28 ENST00000593500.1
ENST00000599385.5
D-box binding PAR bZIP transcription factor
chr6_-_46491431 40.20 ENST00000371374.6
regulator of calcineurin 2
chr7_+_24284181 38.68 ENST00000407573.5
ENST00000242152.7
neuropeptide Y
chr11_-_117877463 38.28 ENST00000527717.5
FXYD domain containing ion transport regulator 6
chr15_+_75347610 37.63 ENST00000564784.5
ENST00000569035.5
nei like DNA glycosylase 1
chr19_-_49442360 36.90 ENST00000600601.5
solute carrier family 17 member 7
chr14_+_92323154 35.41 ENST00000532405.6
ENST00000676001.1
ENST00000531433.5
solute carrier family 24 member 4
chr19_+_35139724 35.32 ENST00000588715.5
ENST00000588607.5
FXYD domain containing ion transport regulator 1
chr1_-_21669301 35.20 ENST00000542643.6
ENST00000317967.11
ENST00000374765.9
ENST00000290101.8
RAP1 GTPase activating protein
chr8_-_22232020 35.19 ENST00000454243.7
ENST00000321613.7
phytanoyl-CoA 2-hydroxylase interacting protein
chr1_+_152663378 34.99 ENST00000368784.2
late cornified envelope 2D
chr10_-_102418748 34.80 ENST00000020673.6
pleckstrin and Sec7 domain containing
chr12_+_53050179 34.62 ENST00000546602.5
ENST00000552570.5
ENST00000549700.5
tensin 2
chr19_-_38229654 33.66 ENST00000412732.5
ENST00000456296.5
double PHD fingers 1
chr12_+_119178920 33.20 ENST00000281938.7
heat shock protein family B (small) member 8
chr4_-_86594037 33.12 ENST00000641050.1
ENST00000641831.1
ENST00000515400.3
ENST00000641391.1
ENST00000641157.1
ENST00000641737.1
ENST00000502302.6
ENST00000640527.1
ENST00000512046.2
ENST00000513186.7
mitogen-activated protein kinase 10
chr12_+_53050014 33.11 ENST00000314250.11
tensin 2
chr11_+_123430259 33.08 ENST00000533341.3
ENST00000635736.2
GRAM domain containing 1B
chr14_-_20802402 32.89 ENST00000412779.2
ribonuclease A family member 1, pancreatic
chr19_+_35140022 32.16 ENST00000588081.5
ENST00000589121.1
FXYD domain containing ion transport regulator 1
chr8_-_143160603 32.03 ENST00000615409.1
ENST00000414417.6
lymphocyte antigen 6 family member H
chr14_-_21025490 31.87 ENST00000553442.5
ENST00000555869.5
ENST00000556457.5
ENST00000397844.6
ENST00000554415.5
ENST00000556974.5
ENST00000554419.5
ENST00000298687.9
ENST00000397858.5
ENST00000360463.7
ENST00000350792.7
ENST00000397847.6
NDRG family member 2
chr3_-_58577367 31.86 ENST00000464064.5
ENST00000360997.7
family with sequence similarity 107 member A
chr6_-_31546552 31.77 ENST00000303892.10
ENST00000376151.4
ATPase H+ transporting V1 subunit G2
chr11_+_57598184 31.11 ENST00000677625.1
ENST00000676670.1
serpin family G member 1
chr15_+_75347030 30.41 ENST00000566313.5
ENST00000355059.9
ENST00000568059.1
ENST00000568881.1
nei like DNA glycosylase 1
chr16_-_21278282 30.33 ENST00000572914.2
crystallin mu
chr4_-_687325 30.27 ENST00000503156.5
solute carrier family 49 member 3
chr22_+_22697789 30.19 ENST00000390306.2
immunoglobulin lambda variable 2-23
chr19_+_58278948 29.90 ENST00000621650.2
ENST00000591325.1
zinc finger protein 8
ZNF8-ERVK3-1 readthrough
chr17_-_44911281 29.84 ENST00000638304.1
ENST00000591880.2
ENST00000586125.2
ENST00000639921.1
glial fibrillary acidic protein
chr14_+_74084947 29.55 ENST00000674221.1
ENST00000554938.2
lin-52 DREAM MuvB core complex component
chr2_+_95025700 29.25 ENST00000309988.9
ENST00000353004.7
ENST00000354078.7
ENST00000349807.3
mal, T cell differentiation protein
chr6_-_46491956 28.52 ENST00000306764.11
regulator of calcineurin 2
chr10_+_104275126 28.42 ENST00000369707.2
glutathione S-transferase omega 2
chr19_-_34677157 28.28 ENST00000601241.6
secretoglobin family 2B member 2
chr20_+_46029206 28.24 ENST00000243964.7
solute carrier family 12 member 5
chr20_+_46029165 28.16 ENST00000616201.4
ENST00000616202.4
ENST00000616933.4
ENST00000626937.2
solute carrier family 12 member 5
chrX_-_119606412 28.13 ENST00000304449.8
NFKB repressing factor
chr9_+_17579059 27.99 ENST00000380607.5
SH3 domain containing GRB2 like 2, endophilin A1
chr8_+_22053543 27.47 ENST00000519850.5
ENST00000381470.7
dematin actin binding protein
chr19_+_49877660 27.27 ENST00000535102.6
TBC1 domain family member 17
chr4_-_185956348 27.07 ENST00000431902.5
ENST00000284776.11
ENST00000415274.5
sorbin and SH3 domain containing 2
chr1_+_43650118 27.04 ENST00000372396.4
lysine demethylase 4A
chr1_-_84997079 26.88 ENST00000284027.5
ENST00000370608.8
mucolipin TRP cation channel 2
chr1_-_40665654 26.82 ENST00000372684.8
regulating synaptic membrane exocytosis 3
chr11_+_121576760 26.09 ENST00000532694.5
ENST00000534286.5
sortilin related receptor 1
chr14_-_100548098 25.54 ENST00000554356.6
brain enriched guanylate kinase associated
chr1_+_160127672 25.38 ENST00000447527.1
ATPase Na+/K+ transporting subunit alpha 2
chr22_-_19525369 25.24 ENST00000403084.1
ENST00000413119.2
claudin 5
chr19_+_49878052 25.23 ENST00000599049.6
TBC1 domain family member 17
chr17_-_58529344 25.22 ENST00000317268.7
septin 4
chr19_+_45692637 25.10 ENST00000012049.10
ENST00000366382.8
glutaminyl-peptide cyclotransferase like
chr12_+_53938824 25.10 ENST00000243056.5
homeobox C13
chr1_+_152675295 25.03 ENST00000368783.1
late cornified envelope 2C
chr9_-_83956677 25.02 ENST00000376344.8
chromosome 9 open reading frame 64
chrX_-_13938378 24.87 ENST00000398361.7
glycoprotein M6B
chr12_-_70788914 24.83 ENST00000342084.8
protein tyrosine phosphatase receptor type R
chr3_-_49869886 24.83 ENST00000296471.11
ENST00000488336.5
ENST00000477224.6
ENST00000467248.5
ENST00000466940.5
ENST00000463537.5
ENST00000480398.2
CaM kinase like vesicle associated
chr1_-_161309961 24.78 ENST00000533357.5
ENST00000672602.2
ENST00000526189.3
myelin protein zero
chr4_+_4387078 24.67 ENST00000504171.1
neuronal vesicle trafficking associated 1
chr19_+_50203607 24.64 ENST00000642316.2
ENST00000425460.6
ENST00000440075.6
ENST00000376970.6
ENST00000599920.5
myosin heavy chain 14
chr19_+_17215332 24.62 ENST00000263897.10
unconventional SNARE in the ER 1
chr1_+_1435523 24.58 ENST00000338660.5
ENST00000476993.2
ENST00000471398.1
von Willebrand factor A domain containing 1
chr12_+_119178953 24.50 ENST00000674542.1
heat shock protein family B (small) member 8
chr22_+_28742024 24.37 ENST00000216027.8
ENST00000398941.6
HscB mitochondrial iron-sulfur cluster cochaperone
chr19_+_49877425 24.25 ENST00000622860.4
TBC1 domain family member 17
chr2_+_17753852 23.99 ENST00000317402.11
GEN1 Holliday junction 5' flap endonuclease
chrX_-_13938618 23.99 ENST00000454189.6
glycoprotein M6B
chr14_+_94612383 23.92 ENST00000393080.8
ENST00000555820.1
ENST00000393078.5
ENST00000467132.5
serpin family A member 3
chr14_-_21025000 23.80 ENST00000554489.5
ENST00000555657.5
ENST00000557274.5
ENST00000555158.5
ENST00000554833.5
ENST00000555384.5
ENST00000556420.5
ENST00000554893.5
ENST00000553503.5
ENST00000555733.5
ENST00000397856.7
ENST00000553867.5
ENST00000556147.6
ENST00000556008.5
ENST00000557182.5
ENST00000554483.5
ENST00000556688.5
ENST00000397853.7
ENST00000556329.6
ENST00000397851.6
ENST00000554143.5
ENST00000555142.5
ENST00000557676.5
ENST00000556924.5
NDRG family member 2
chr19_+_17215382 23.49 ENST00000595101.5
ENST00000596136.5
ENST00000445667.6
unconventional SNARE in the ER 1
chr3_-_58577648 23.33 ENST00000394481.5
family with sequence similarity 107 member A
chr2_+_17754116 23.30 ENST00000381254.7
ENST00000524465.5
ENST00000532257.1
GEN1 Holliday junction 5' flap endonuclease
chr8_+_141128581 23.27 ENST00000519811.6
DENN domain containing 3
chr16_-_70439045 23.22 ENST00000342907.3
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr1_+_35557435 23.22 ENST00000373253.7
neurochondrin
chr15_+_44288701 22.98 ENST00000299957.11
ENST00000559222.5
ENST00000650436.1
golgi membrane protein 2
chr20_+_43514492 22.97 ENST00000373135.8
ENST00000373134.5
L3MBTL histone methyl-lysine binding protein 1
chr8_+_135458027 22.92 ENST00000524199.5
KH RNA binding domain containing, signal transduction associated 3
chr1_+_204870831 22.87 ENST00000404076.5
ENST00000539706.6
neurofascin
chr4_+_186191549 22.81 ENST00000378802.5
cytochrome P450 family 4 subfamily V member 2
chr7_-_137343688 22.73 ENST00000348225.7
pleiotrophin
chr12_-_16600703 22.73 ENST00000616247.4
LIM domain only 3
chr8_+_28890365 22.53 ENST00000519662.5
ENST00000558662.5
ENST00000287701.15
ENST00000523613.5
ENST00000560599.5
ENST00000397358.7
homeobox containing 1
chr10_-_69416912 22.33 ENST00000373306.5
tachykinin receptor 2
chr19_-_38229714 22.24 ENST00000416611.5
double PHD fingers 1
chr1_+_150257247 22.23 ENST00000647854.1
carbonic anhydrase 14
chr19_+_17215716 22.02 ENST00000593597.1
unconventional SNARE in the ER 1
chr16_-_30091226 22.01 ENST00000279386.6
ENST00000627355.2
T-box transcription factor 6
chr17_-_44968263 21.83 ENST00000253407.4
complement C1q like 1
chr8_-_143160248 21.64 ENST00000342752.9
lymphocyte antigen 6 family member H
chr1_-_203351115 21.58 ENST00000354955.5
fibromodulin
chr19_-_56671746 21.58 ENST00000537055.4
ENST00000601659.1
zinc finger protein 835
chr4_+_127632926 21.57 ENST00000335251.11
inturned planar cell polarity protein
chr7_-_712437 21.53 ENST00000360274.8
protein kinase cAMP-dependent type I regulatory subunit beta
chr22_-_36817510 21.49 ENST00000443735.1
parvalbumin
chr6_-_39934450 21.48 ENST00000340692.10
ENST00000373195.7
ENST00000373188.6
molybdenum cofactor synthesis 1
chr10_+_103277129 21.43 ENST00000369849.9
internexin neuronal intermediate filament protein alpha
chr10_+_99329349 21.37 ENST00000356713.5
cyclin and CBS domain divalent metal cation transport mediator 1
chr1_-_202710428 21.20 ENST00000367268.5
synaptotagmin 2
chr14_-_100568475 21.19 ENST00000553553.6
brain enriched guanylate kinase associated
chr4_-_56656507 21.14 ENST00000381255.7
ENST00000317745.11
ENST00000555760.6
ENST00000556614.6
HOP homeobox
chr4_+_4387039 21.12 ENST00000621129.4
neuronal vesicle trafficking associated 1
chr11_+_73308237 21.10 ENST00000263674.4
Rho guanine nucleotide exchange factor 17
chr12_+_21526287 20.92 ENST00000256969.7
spexin hormone
chr9_+_128203371 20.85 ENST00000475805.5
ENST00000372923.8
ENST00000341179.11
ENST00000393594.7
dynamin 1
chr19_+_58183375 20.75 ENST00000326804.8
ENST00000610905.4
ENST00000597528.1
zinc finger protein 274
chr1_+_22637580 20.68 ENST00000402322.1
complement C1q A chain
chr9_-_95317671 20.66 ENST00000490972.7
ENST00000647778.1
ENST00000649611.1
ENST00000289081.8
FA complementation group C
chr11_-_132943671 20.65 ENST00000331898.11
opioid binding protein/cell adhesion molecule like
chr6_-_89315291 20.63 ENST00000402938.4
gamma-aminobutyric acid type A receptor subunit rho2
chr9_+_128203397 20.49 ENST00000628346.2
ENST00000486160.3
ENST00000627061.2
ENST00000627543.2
ENST00000634267.2
dynamin 1
chr12_-_48865863 20.46 ENST00000309739.6
Rho family GTPase 1
chr3_-_46882165 20.42 ENST00000431168.1
ENST00000654597.1
myosin light chain 3
chr3_+_38305936 20.39 ENST00000273173.4
solute carrier family 22 member 14
chr17_+_42682470 20.26 ENST00000264638.9
contactin associated protein 1
chr4_-_56656448 20.07 ENST00000553379.6
HOP homeobox
chr1_+_226548747 19.98 ENST00000366788.8
ENST00000366789.5
stum, mechanosensory transduction mediator homolog
chr1_-_20486197 19.94 ENST00000375078.4
calcium/calmodulin dependent protein kinase II inhibitor 1
chr6_-_32224060 19.94 ENST00000375023.3
notch receptor 4
chr7_+_24285107 19.94 ENST00000405982.1
neuropeptide Y
chr3_-_38029604 19.90 ENST00000334661.5
phospholipase C delta 1
chr1_+_2073986 19.84 ENST00000461106.6
protein kinase C zeta
chr1_-_16431371 19.82 ENST00000612240.1
spermatogenesis associated 21
chr17_-_58529277 19.81 ENST00000579371.5
septin 4
chr20_+_43514426 19.71 ENST00000422861.3
L3MBTL histone methyl-lysine binding protein 1
chr19_+_40191410 19.69 ENST00000253055.8
mitogen-activated protein kinase kinase kinase 10
chr17_-_58529303 19.63 ENST00000580844.5
septin 4
chr2_+_232633551 19.58 ENST00000264059.8
EF-hand domain family member D1
chr7_-_137343752 19.55 ENST00000393083.2
pleiotrophin
chr3_-_58627567 19.51 ENST00000649301.1
family with sequence similarity 107 member A
chr16_+_1333631 19.46 ENST00000397488.6
ENST00000562208.5
ENST00000568887.5
ENST00000426824.8
BAI1 associated protein 3
chr13_-_21459253 19.34 ENST00000400590.8
ENST00000382466.7
ENST00000415724.2
ENST00000542645.5
zinc finger DHHC-type palmitoyltransferase 20
chr17_+_45894515 19.33 ENST00000680674.1
ENST00000535772.6
ENST00000351559.10
ENST00000262410.10
ENST00000344290.10
microtubule associated protein tau
chr1_-_182953132 19.29 ENST00000367547.8
SHC binding and spindle associated 1 like
chr7_-_158587710 19.25 ENST00000389416.8
protein tyrosine phosphatase receptor type N2
chr19_+_49877694 19.20 ENST00000221543.10
TBC1 domain family member 17
chr20_-_4823597 19.20 ENST00000379400.8
Ras association domain family member 2
chr11_-_790062 19.15 ENST00000330106.5
cell cycle exit and neuronal differentiation 1
chr22_+_22758698 19.05 ENST00000390312.2
immunoglobulin lambda variable 2-14
chr21_+_37006693 19.02 ENST00000329553.3
ripply transcriptional repressor 3
chr1_-_182391363 18.97 ENST00000417584.6
glutamate-ammonia ligase
chr7_+_65873068 18.96 ENST00000360768.5
vitamin K epoxide reductase complex subunit 1 like 1
chr4_+_165378998 18.94 ENST00000402744.9
carboxypeptidase E
chrX_+_43656289 18.91 ENST00000338702.4
monoamine oxidase A
chr17_+_43780425 18.89 ENST00000449302.8
CFAP97 domain containing 1
chr16_+_72063226 18.89 ENST00000540303.7
ENST00000356967.6
ENST00000561690.1
haptoglobin-related protein
chr4_-_17810686 18.78 ENST00000382247.6
DDB1 and CUL4 associated factor 16
chr14_+_22495890 18.72 ENST00000390494.1
T cell receptor alpha joining 43
chr16_+_10386049 18.71 ENST00000562527.5
ENST00000396559.5
ENST00000396560.6
ENST00000562102.5
ENST00000543967.5
ENST00000569939.5
ENST00000569900.5
activating transcription factor 7 interacting protein 2
chr11_-_35525603 18.70 ENST00000529303.1
ENST00000619888.5
ENST00000622144.4
peptidase domain containing associated with muscle regeneration 1
chr18_-_6414885 18.66 ENST00000317931.12
ENST00000400104.7
L3MBTL histone methyl-lysine binding protein 4
chr3_+_101724602 18.63 ENST00000341893.8
centrosomal protein 97
chr11_+_17719564 18.62 ENST00000250003.4
myogenic differentiation 1
chr11_+_61752603 18.62 ENST00000278836.10
myelin regulatory factor
chr3_+_111998739 18.58 ENST00000393917.6
ENST00000273368.8
transgelin 3
chr3_+_111998915 18.58 ENST00000478951.6
transgelin 3
chr5_+_75512058 18.57 ENST00000514296.5
DNA polymerase kappa
chr5_+_73626158 18.54 ENST00000296794.10
ENST00000545377.5
ENST00000509848.5
ENST00000513042.7
Rho guanine nucleotide exchange factor 28
chr18_-_67516707 18.54 ENST00000310045.9
dermatan sulfate epimerase like
chr16_+_1989949 18.48 ENST00000248121.7
ENST00000618464.1
synaptogyrin 3
chr19_-_32971909 18.47 ENST00000305768.10
ENST00000590597.6
ENST00000591863.1
centrosomal protein 89
chr7_-_101180215 18.45 ENST00000455377.5
ENST00000443096.1
ENST00000300303.7
N-acetyltransferase 16 (putative)
chr2_-_219308963 18.42 ENST00000423636.6
ENST00000442029.5
ENST00000412847.5
protein tyrosine phosphatase receptor type N
chr16_+_56336805 18.30 ENST00000564727.2
G protein subunit alpha o1
chr12_-_6124662 18.30 ENST00000261405.10
von Willebrand factor
chr11_+_14643826 18.27 ENST00000455098.2
phosphodiesterase 3B
chr7_-_98869866 18.23 ENST00000416379.6
transmembrane protein 130
chr1_-_182391783 18.20 ENST00000331872.11
ENST00000339526.8
glutamate-ammonia ligase
chr15_-_82699893 18.16 ENST00000642989.2
adaptor related protein complex 3 subunit beta 2
chr22_+_45502832 18.13 ENST00000455233.5
ENST00000402984.7
ENST00000262722.11
ENST00000327858.11
ENST00000442170.6
ENST00000340923.9
fibulin 1
chr19_-_12365655 18.05 ENST00000242804.9
zinc finger protein 442
chr3_+_46882180 18.05 ENST00000427125.6
ENST00000430002.6
parathyroid hormone 1 receptor
chr17_+_45894644 18.01 ENST00000680542.1
ENST00000334239.12
ENST00000446361.7
microtubule associated protein tau
chr19_+_35138993 18.00 ENST00000612146.4
ENST00000589209.5
FXYD domain containing ion transport regulator 1
chr12_-_49897056 17.92 ENST00000552863.5
Fas apoptotic inhibitory molecule 2
chr7_+_65873091 17.88 ENST00000648187.1
vitamin K epoxide reductase complex subunit 1 like 1
chr6_-_28399731 17.84 ENST00000396827.3
ENST00000361028.5
ENST00000684592.1
zinc finger and SCAN domain containing 12
chr6_+_33075952 17.80 ENST00000418931.7
major histocompatibility complex, class II, DP beta 1
chr13_-_44437214 17.68 ENST00000622051.1
TSC22 domain family member 1
chr19_-_55157725 17.60 ENST00000344887.10
ENST00000665070.1
troponin I3, cardiac type
chr12_+_10212867 17.49 ENST00000545047.5
ENST00000266458.10
ENST00000629504.1
ENST00000543602.5
ENST00000545887.1
GABA type A receptor associated protein like 1
chr1_-_45339995 17.48 ENST00000488731.6
ENST00000435155.1
mutY DNA glycosylase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
18.2 54.5 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
16.0 47.9 GO:0042137 sequestering of neurotransmitter(GO:0042137)
15.8 47.3 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
14.8 88.7 GO:0010731 protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734)
14.0 42.0 GO:0035691 macrophage migration inhibitory factor signaling pathway(GO:0035691)
13.8 41.3 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
12.6 214.6 GO:0007021 tubulin complex assembly(GO:0007021)
12.3 37.0 GO:1904692 positive regulation of type B pancreatic cell proliferation(GO:1904692)
11.8 35.5 GO:0051946 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
10.8 43.3 GO:0002357 defense response to tumor cell(GO:0002357)
10.4 31.1 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
9.9 39.8 GO:1902228 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141)
9.4 28.3 GO:0007181 transforming growth factor beta receptor complex assembly(GO:0007181)
9.4 56.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
9.3 37.2 GO:0006542 glutamine biosynthetic process(GO:0006542)
8.7 26.1 GO:1902769 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
8.6 25.7 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
8.4 58.6 GO:0032100 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
8.1 56.8 GO:0045007 depurination(GO:0045007)
7.6 68.6 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
7.6 30.3 GO:0046968 peptide antigen transport(GO:0046968)
7.5 37.3 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
7.0 28.0 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
6.9 20.8 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279) positive regulation of calcium:sodium antiporter activity(GO:1903281)
6.9 20.7 GO:1904603 regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204)
6.6 33.0 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
6.6 19.7 GO:0046878 positive regulation of saliva secretion(GO:0046878)
6.5 19.5 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
6.4 19.2 GO:0060988 lipid tube assembly(GO:0060988)
6.1 12.2 GO:2001025 positive regulation of response to drug(GO:2001025)
6.1 42.6 GO:0051013 microtubule severing(GO:0051013)
5.9 70.3 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
5.8 17.4 GO:0050760 negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
5.8 23.2 GO:0035627 ceramide transport(GO:0035627)
5.8 23.2 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
5.8 23.0 GO:0018199 peptidyl-glutamine modification(GO:0018199)
5.7 11.5 GO:0071284 cellular response to lead ion(GO:0071284)
5.7 22.8 GO:0010430 fatty acid omega-oxidation(GO:0010430)
5.7 22.7 GO:0009182 purine deoxyribonucleoside diphosphate metabolic process(GO:0009182)
5.6 22.3 GO:0035106 operant conditioning(GO:0035106)
5.5 21.8 GO:0099558 maintenance of synapse structure(GO:0099558)
5.4 21.6 GO:0015855 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
5.4 16.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
5.3 15.9 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
5.3 15.9 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
5.3 21.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
5.2 15.7 GO:0010958 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) regulation of amino acid import(GO:0010958) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
5.2 56.8 GO:0006285 base-excision repair, AP site formation(GO:0006285)
5.1 20.6 GO:1905224 clathrin-coated pit assembly(GO:1905224)
5.1 25.4 GO:0044375 regulation of peroxisome size(GO:0044375)
5.0 15.1 GO:0002461 tolerance induction dependent upon immune response(GO:0002461)
5.0 15.1 GO:0002892 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
5.0 15.0 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
5.0 5.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
4.9 9.8 GO:0035973 aggrephagy(GO:0035973)
4.9 24.6 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
4.8 38.8 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
4.8 38.5 GO:0032534 regulation of microvillus assembly(GO:0032534)
4.8 43.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
4.7 14.2 GO:0038178 complement component C5a signaling pathway(GO:0038178)
4.7 47.0 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
4.7 14.0 GO:0060032 notochord regression(GO:0060032)
4.6 4.6 GO:1902219 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
4.5 125.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
4.4 62.0 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371)
4.4 13.3 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
4.4 13.2 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
4.4 22.0 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
4.4 13.2 GO:0061027 umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027)
4.4 30.7 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
4.4 13.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
4.4 13.1 GO:1904640 response to methionine(GO:1904640)
4.3 13.0 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
4.3 12.9 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
4.3 17.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
4.3 42.8 GO:0043045 DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538)
4.3 68.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
4.2 29.7 GO:0070560 protein secretion by platelet(GO:0070560)
4.2 16.9 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
4.2 12.6 GO:0051939 gamma-aminobutyric acid import(GO:0051939)
4.2 21.0 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
4.2 20.9 GO:1904306 regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
4.2 25.0 GO:0000189 MAPK import into nucleus(GO:0000189)
4.2 16.6 GO:0072369 regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
4.1 12.3 GO:0009386 translational attenuation(GO:0009386)
4.1 16.3 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020) negative regulation of G-protein coupled receptor internalization(GO:1904021)
4.1 36.6 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
4.0 16.0 GO:0019086 late viral transcription(GO:0019086)
4.0 19.8 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
3.9 15.8 GO:2001034 histone H3-K36 dimethylation(GO:0097676) positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
3.9 7.8 GO:0021966 corticospinal neuron axon guidance(GO:0021966) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
3.9 19.6 GO:1902093 positive regulation of sperm motility(GO:1902093)
3.9 11.7 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
3.9 27.2 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
3.9 58.1 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
3.9 11.6 GO:1902490 regulation of sperm capacitation(GO:1902490)
3.9 3.9 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
3.9 27.0 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112)
3.8 11.5 GO:0030186 melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187)
3.8 11.4 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
3.8 18.9 GO:0030070 insulin processing(GO:0030070)
3.8 60.2 GO:0098712 L-glutamate import across plasma membrane(GO:0098712)
3.8 11.3 GO:0061536 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
3.7 29.8 GO:0071907 determination of digestive tract left/right asymmetry(GO:0071907)
3.7 7.5 GO:0070256 negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256)
3.7 11.2 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
3.6 7.3 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
3.6 7.3 GO:0097017 renal protein absorption(GO:0097017)
3.6 14.4 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
3.6 17.8 GO:0032632 interleukin-3 production(GO:0032632)
3.6 24.9 GO:1990822 basic amino acid transmembrane transport(GO:1990822)
3.5 10.6 GO:0061184 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) positive regulation of dermatome development(GO:0061184)
3.5 52.6 GO:0035878 nail development(GO:0035878)
3.5 10.5 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
3.5 28.0 GO:0016191 synaptic vesicle uncoating(GO:0016191)
3.5 3.5 GO:0086068 Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068)
3.5 10.4 GO:0099515 actin filament-based transport(GO:0099515)
3.5 20.8 GO:0002225 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
3.4 3.4 GO:0046668 regulation of retinal cell programmed cell death(GO:0046668)
3.4 10.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
3.4 13.6 GO:0072660 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
3.4 10.2 GO:0008614 pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819)
3.4 33.8 GO:0021633 optic nerve structural organization(GO:0021633)
3.4 10.1 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) positive regulation of chromatin silencing(GO:0031937)
3.3 3.3 GO:0043932 ossification involved in bone remodeling(GO:0043932)
3.3 13.3 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
3.3 10.0 GO:0044805 late nucleophagy(GO:0044805)
3.3 9.9 GO:0018094 protein polyglycylation(GO:0018094)
3.3 3.3 GO:0071280 cellular response to copper ion(GO:0071280)
3.3 55.3 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
3.3 39.0 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
3.2 22.7 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
3.2 22.6 GO:1902075 cellular response to salt(GO:1902075)
3.2 12.8 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
3.2 9.6 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
3.2 6.4 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
3.2 6.4 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
3.2 12.7 GO:0097167 circadian regulation of translation(GO:0097167)
3.1 25.0 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
3.1 9.3 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
3.1 15.5 GO:0001955 blood vessel maturation(GO:0001955)
3.1 12.4 GO:0080154 regulation of fertilization(GO:0080154)
3.1 15.4 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
3.0 6.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
3.0 51.5 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
3.0 9.0 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
3.0 9.0 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
3.0 39.2 GO:0007258 JUN phosphorylation(GO:0007258)
3.0 27.0 GO:0060267 positive regulation of respiratory burst(GO:0060267)
3.0 9.0 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
3.0 8.9 GO:1905071 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
3.0 26.7 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
2.9 17.5 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
2.9 26.0 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
2.9 31.6 GO:0042373 vitamin K metabolic process(GO:0042373)
2.9 14.3 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415) regulation of skeletal muscle tissue regeneration(GO:0043416)
2.9 25.7 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
2.8 19.9 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
2.8 28.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
2.8 31.1 GO:0097186 amelogenesis(GO:0097186)
2.8 5.6 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
2.8 8.3 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
2.7 13.6 GO:0032286 central nervous system myelin maintenance(GO:0032286)
2.7 16.3 GO:0036018 cellular response to erythropoietin(GO:0036018)
2.7 16.3 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
2.7 10.8 GO:0030035 microspike assembly(GO:0030035)
2.7 16.1 GO:0007000 nucleolus organization(GO:0007000)
2.7 8.0 GO:0010133 proline catabolic process to glutamate(GO:0010133)
2.7 10.7 GO:0071409 cellular response to cycloheximide(GO:0071409)
2.7 13.4 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
2.6 5.3 GO:0007525 somatic muscle development(GO:0007525)
2.6 29.0 GO:0038003 opioid receptor signaling pathway(GO:0038003)
2.6 7.9 GO:0016476 regulation of embryonic cell shape(GO:0016476) glomerular visceral epithelial cell migration(GO:0090521)
2.6 5.3 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
2.6 44.5 GO:0001829 trophectodermal cell differentiation(GO:0001829)
2.6 7.8 GO:0071486 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009)
2.6 13.0 GO:0045925 positive regulation of female receptivity(GO:0045925)
2.6 23.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
2.6 12.8 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
2.6 38.3 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
2.5 33.1 GO:0030050 vesicle transport along actin filament(GO:0030050)
2.5 12.7 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
2.5 12.7 GO:0030259 lipid glycosylation(GO:0030259)
2.5 25.3 GO:1903358 regulation of Golgi organization(GO:1903358)
2.5 30.3 GO:0070327 thyroid hormone transport(GO:0070327)
2.5 7.6 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
2.5 22.6 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
2.5 5.0 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
2.5 24.8 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
2.5 7.4 GO:0001923 B-1 B cell differentiation(GO:0001923)
2.5 19.7 GO:0007256 activation of JNKK activity(GO:0007256)
2.5 68.9 GO:0014850 response to muscle activity(GO:0014850)
2.5 7.4 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
2.5 7.4 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
2.4 4.8 GO:0021558 trochlear nerve development(GO:0021558)
2.4 9.5 GO:0002215 defense response to nematode(GO:0002215)
2.4 7.1 GO:0042560 folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
2.4 11.9 GO:0032899 regulation of neurotrophin production(GO:0032899)
2.4 23.6 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
2.4 7.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
2.4 9.4 GO:0019805 quinolinate biosynthetic process(GO:0019805)
2.4 7.1 GO:0071529 cementum mineralization(GO:0071529)
2.3 9.4 GO:0015793 glycerol transport(GO:0015793)
2.3 21.1 GO:0042487 regulation of odontogenesis of dentin-containing tooth(GO:0042487)
2.3 35.1 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
2.3 7.0 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
2.3 11.6 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
2.3 69.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
2.3 9.3 GO:0072014 proximal tubule development(GO:0072014)
2.3 157.4 GO:0006501 C-terminal protein lipidation(GO:0006501)
2.3 92.6 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
2.3 11.6 GO:1902613 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
2.3 13.9 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
2.3 4.6 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
2.2 4.5 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
2.2 13.4 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
2.2 11.2 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
2.2 26.6 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
2.2 17.6 GO:0003406 retinal pigment epithelium development(GO:0003406)
2.2 4.4 GO:1905154 negative regulation of membrane invagination(GO:1905154)
2.2 13.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
2.2 10.9 GO:0038170 somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170)
2.2 10.9 GO:2000834 androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
2.2 65.2 GO:0097503 sialylation(GO:0097503)
2.2 73.8 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
2.2 17.3 GO:0070995 NADPH oxidation(GO:0070995)
2.2 308.9 GO:0006958 complement activation, classical pathway(GO:0006958)
2.2 8.6 GO:1903631 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
2.1 12.9 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
2.1 6.4 GO:0032782 bile acid secretion(GO:0032782)
2.1 10.5 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
2.1 10.4 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
2.1 12.4 GO:0006543 glutamine catabolic process(GO:0006543)
2.1 4.1 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
2.1 6.2 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
2.1 4.1 GO:0046016 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) carbon catabolite activation of transcription(GO:0045991) positive regulation of transcription by glucose(GO:0046016)
2.1 6.2 GO:0019075 virus maturation(GO:0019075)
2.0 2.0 GO:0048242 regulation of epinephrine secretion(GO:0014060) epinephrine secretion(GO:0048242)
2.0 6.1 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
2.0 12.2 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
2.0 10.1 GO:0071896 protein localization to adherens junction(GO:0071896)
2.0 26.2 GO:1900364 single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) negative regulation of mRNA polyadenylation(GO:1900364)
2.0 10.0 GO:2000382 positive regulation of mesoderm development(GO:2000382)
2.0 6.0 GO:0045110 intermediate filament bundle assembly(GO:0045110)
2.0 6.0 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
2.0 4.0 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
2.0 11.9 GO:1904274 tricellular tight junction assembly(GO:1904274)
2.0 5.9 GO:0048318 axial mesoderm development(GO:0048318)
1.9 7.8 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
1.9 52.5 GO:0071420 cellular response to histamine(GO:0071420)
1.9 19.2 GO:0033123 positive regulation of purine nucleotide catabolic process(GO:0033123)
1.9 5.7 GO:0003011 diaphragm contraction(GO:0002086) involuntary skeletal muscle contraction(GO:0003011)
1.9 9.6 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
1.9 11.4 GO:0006489 dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465)
1.9 13.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
1.9 5.7 GO:0061073 ciliary body morphogenesis(GO:0061073)
1.9 11.4 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
1.9 11.2 GO:0018343 protein farnesylation(GO:0018343)
1.9 14.9 GO:0006013 mannose metabolic process(GO:0006013)
1.8 7.4 GO:0014807 regulation of somitogenesis(GO:0014807)
1.8 5.5 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
1.8 9.1 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181)
1.8 10.8 GO:0046092 deoxycytidine metabolic process(GO:0046092)
1.8 5.3 GO:0042412 taurine biosynthetic process(GO:0042412)
1.8 14.2 GO:0006477 protein sulfation(GO:0006477)
1.8 35.2 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
1.8 10.5 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
1.8 8.8 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
1.7 10.5 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
1.7 34.6 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
1.7 31.1 GO:0097091 synaptic vesicle clustering(GO:0097091)
1.7 15.5 GO:0032119 sequestering of zinc ion(GO:0032119)
1.7 15.4 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
1.7 5.1 GO:1990637 response to prolactin(GO:1990637)
1.7 15.3 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
1.7 13.6 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
1.7 8.5 GO:0051029 rRNA transport(GO:0051029)
1.7 10.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
1.7 15.3 GO:0006857 oligopeptide transport(GO:0006857)
1.7 18.6 GO:1902018 negative regulation of cilium assembly(GO:1902018)
1.7 6.8 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
1.7 5.0 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
1.7 49.6 GO:0071800 podosome assembly(GO:0071800)
1.7 21.5 GO:0034770 histone H4-K20 methylation(GO:0034770)
1.6 4.9 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
1.6 16.2 GO:2000291 regulation of myoblast proliferation(GO:2000291)
1.6 6.5 GO:0060282 positive regulation of oocyte development(GO:0060282)
1.6 4.8 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
1.6 3.2 GO:0032881 regulation of polysaccharide metabolic process(GO:0032881) regulation of glycogen metabolic process(GO:0070873)
1.6 1.6 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
1.6 55.8 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
1.6 8.0 GO:0006574 valine catabolic process(GO:0006574)
1.6 9.5 GO:0061205 alveolar primary septum development(GO:0061143) paramesonephric duct development(GO:0061205)
1.6 7.9 GO:1901569 leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569)
1.6 25.3 GO:0014029 neural crest formation(GO:0014029)
1.6 26.9 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
1.6 6.3 GO:0002644 negative regulation of tolerance induction(GO:0002644)
1.6 11.0 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
1.6 3.1 GO:0060979 cardiac left ventricle formation(GO:0003218) vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
1.6 17.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
1.6 10.9 GO:0010968 regulation of microtubule nucleation(GO:0010968)
1.5 18.6 GO:0060539 diaphragm development(GO:0060539)
1.5 4.6 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
1.5 9.2 GO:1990034 calcium ion export from cell(GO:1990034)
1.5 4.6 GO:0061107 seminal vesicle development(GO:0061107)
1.5 7.6 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
1.5 71.2 GO:0018149 peptide cross-linking(GO:0018149)
1.5 4.5 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
1.5 1.5 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
1.5 10.5 GO:0042866 pyruvate biosynthetic process(GO:0042866)
1.5 6.0 GO:0090241 negative regulation of histone H4 acetylation(GO:0090241)
1.5 10.5 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
1.5 1.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
1.5 92.0 GO:1902017 regulation of cilium assembly(GO:1902017)
1.5 5.9 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
1.5 1.5 GO:0039020 pronephric nephron tubule development(GO:0039020)
1.4 5.8 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
1.4 5.8 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
1.4 19.8 GO:0006751 glutathione catabolic process(GO:0006751)
1.4 5.7 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
1.4 14.1 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
1.4 7.0 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
1.4 4.2 GO:0030920 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
1.4 2.8 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
1.4 15.3 GO:0036155 acylglycerol acyl-chain remodeling(GO:0036155)
1.4 19.5 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
1.4 40.3 GO:0050919 negative chemotaxis(GO:0050919)
1.4 4.1 GO:0032571 response to vitamin K(GO:0032571)
1.4 44.8 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
1.4 4.1 GO:0060398 mineralocorticoid receptor signaling pathway(GO:0031959) regulation of growth hormone receptor signaling pathway(GO:0060398)
1.4 8.1 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
1.3 16.2 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
1.3 5.4 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
1.3 1.3 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
1.3 2.7 GO:1903596 regulation of gap junction assembly(GO:1903596)
1.3 10.6 GO:0046415 urate metabolic process(GO:0046415)
1.3 4.0 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
1.3 4.0 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
1.3 7.9 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
1.3 3.9 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
1.3 6.5 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
1.3 14.4 GO:0001675 acrosome assembly(GO:0001675)
1.3 18.2 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
1.3 7.8 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
1.3 9.1 GO:0034086 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
1.3 3.9 GO:0042360 vitamin E metabolic process(GO:0042360)
1.3 1.3 GO:0009624 response to nematode(GO:0009624)
1.3 16.8 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
1.3 14.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
1.3 5.2 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
1.3 6.4 GO:0042364 water-soluble vitamin biosynthetic process(GO:0042364)
1.3 3.9 GO:0090675 intermicrovillar adhesion(GO:0090675)
1.3 6.4 GO:0002870 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
1.3 5.1 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
1.3 7.6 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
1.3 3.8 GO:0042631 cellular response to water deprivation(GO:0042631)
1.3 21.3 GO:0034389 lipid particle organization(GO:0034389)
1.2 15.0 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
1.2 3.7 GO:0002503 peptide antigen assembly with MHC class II protein complex(GO:0002503)
1.2 13.7 GO:0016322 neuron remodeling(GO:0016322)
1.2 4.9 GO:0016098 monoterpenoid metabolic process(GO:0016098)
1.2 30.8 GO:0048266 behavioral response to pain(GO:0048266)
1.2 3.7 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
1.2 7.4 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
1.2 6.1 GO:0071109 superior temporal gyrus development(GO:0071109)
1.2 49.7 GO:0070884 regulation of calcineurin-NFAT signaling cascade(GO:0070884)
1.2 13.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
1.2 4.8 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
1.2 6.0 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
1.2 10.8 GO:0042428 serotonin metabolic process(GO:0042428)
1.2 8.4 GO:0036152 phosphatidylethanolamine acyl-chain remodeling(GO:0036152)
1.2 1.2 GO:1900094 nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry(GO:1900094) nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900164)
1.2 4.7 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
1.2 5.9 GO:0002778 antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778)
1.2 92.1 GO:1903779 regulation of cardiac conduction(GO:1903779)
1.2 18.6 GO:0003254 regulation of membrane depolarization(GO:0003254)
1.2 7.0 GO:0001554 luteolysis(GO:0001554)
1.2 9.3 GO:0010623 programmed cell death involved in cell development(GO:0010623)
1.2 52.2 GO:0003009 skeletal muscle contraction(GO:0003009)
1.2 2.3 GO:1900005 positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573)
1.2 4.6 GO:0038161 prolactin signaling pathway(GO:0038161)
1.2 13.9 GO:0014010 Schwann cell proliferation(GO:0014010)
1.2 20.7 GO:0071872 response to epinephrine(GO:0071871) cellular response to epinephrine stimulus(GO:0071872)
1.2 15.0 GO:0006705 mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212)
1.1 19.5 GO:0007130 synaptonemal complex assembly(GO:0007130)
1.1 5.7 GO:0046208 spermine catabolic process(GO:0046208)
1.1 9.2 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
1.1 16.0 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
1.1 34.2 GO:0006706 steroid catabolic process(GO:0006706)
1.1 10.3 GO:0042148 strand invasion(GO:0042148)
1.1 21.6 GO:0021513 spinal cord dorsal/ventral patterning(GO:0021513)
1.1 2.3 GO:0006258 UDP-glucose catabolic process(GO:0006258)
1.1 21.5 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
1.1 3.4 GO:0034499 late endosome to Golgi transport(GO:0034499)
1.1 45.8 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
1.1 22.3 GO:0006068 ethanol catabolic process(GO:0006068)
1.1 10.0 GO:0001542 ovulation from ovarian follicle(GO:0001542)
1.1 15.5 GO:0045109 intermediate filament organization(GO:0045109)
1.1 4.4 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
1.1 9.9 GO:0007512 adult heart development(GO:0007512)
1.1 20.7 GO:0097150 neuronal stem cell population maintenance(GO:0097150)
1.1 10.8 GO:1902669 positive regulation of axon guidance(GO:1902669)
1.1 4.3 GO:0019418 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
1.1 17.1 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
1.1 6.4 GO:0072592 oxygen metabolic process(GO:0072592)
1.1 6.4 GO:0090527 actin filament reorganization(GO:0090527)
1.1 18.0 GO:0002026 regulation of the force of heart contraction(GO:0002026)
1.0 13.6 GO:0070571 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
1.0 3.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
1.0 7.3 GO:0060481 lobar bronchus epithelium development(GO:0060481)
1.0 2.1 GO:0034729 histone H3-K79 methylation(GO:0034729)
1.0 6.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
1.0 28.8 GO:0021772 olfactory bulb development(GO:0021772)
1.0 9.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
1.0 6.1 GO:0002024 diet induced thermogenesis(GO:0002024)
1.0 5.1 GO:0016075 rRNA catabolic process(GO:0016075)
1.0 22.0 GO:0098743 cell aggregation(GO:0098743)
1.0 43.9 GO:0050853 B cell receptor signaling pathway(GO:0050853)
1.0 6.9 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
1.0 12.8 GO:0006600 creatine metabolic process(GO:0006600)
1.0 5.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
1.0 4.9 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
1.0 4.8 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
1.0 7.8 GO:0007252 I-kappaB phosphorylation(GO:0007252)
1.0 45.5 GO:0051646 mitochondrion localization(GO:0051646)
1.0 30.8 GO:0099601 regulation of neurotransmitter receptor activity(GO:0099601)
1.0 2.9 GO:1902430 negative regulation of beta-amyloid formation(GO:1902430)
1.0 95.5 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.9 3.8 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.9 16.0 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.9 11.2 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.9 3.7 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.9 14.9 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.9 18.6 GO:0045687 positive regulation of glial cell differentiation(GO:0045687)
0.9 7.4 GO:0043249 erythrocyte maturation(GO:0043249)
0.9 6.4 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.9 5.5 GO:0072676 lymphocyte migration(GO:0072676)
0.9 14.6 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.9 2.7 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.9 7.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.9 14.5 GO:0005513 detection of calcium ion(GO:0005513)
0.9 4.5 GO:0071027 RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.9 8.0 GO:0002438 acute inflammatory response to antigenic stimulus(GO:0002438)
0.9 15.1 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.9 11.3 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.9 2.6 GO:0032971 regulation of muscle filament sliding(GO:0032971)
0.9 4.3 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.9 1.7 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.9 0.9 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.9 5.1 GO:2000811 negative regulation of anoikis(GO:2000811)
0.8 8.5 GO:0030321 transepithelial chloride transport(GO:0030321)
0.8 22.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.8 8.3 GO:0015871 choline transport(GO:0015871)
0.8 3.3 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.8 10.8 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.8 41.8 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.8 14.6 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.8 16.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.8 4.0 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.8 5.6 GO:0042797 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.8 6.2 GO:0033173 calcineurin-NFAT signaling cascade(GO:0033173)
0.8 7.0 GO:0033005 positive regulation of mast cell activation(GO:0033005)
0.8 4.6 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.8 70.9 GO:0007041 lysosomal transport(GO:0007041)
0.8 2.3 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.8 12.9 GO:0006152 purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.8 1.5 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.8 4.5 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.7 1.5 GO:0015670 carbon dioxide transport(GO:0015670)
0.7 5.2 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.7 3.7 GO:1903975 regulation of glial cell migration(GO:1903975)
0.7 6.6 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.7 13.1 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.7 6.6 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.7 14.5 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.7 6.5 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.7 15.0 GO:0060291 long-term synaptic potentiation(GO:0060291)
0.7 11.4 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
0.7 7.8 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.7 5.0 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.7 2.8 GO:0034343 type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344)
0.7 7.0 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.7 18.3 GO:0050912 detection of chemical stimulus involved in sensory perception of taste(GO:0050912)
0.7 21.8 GO:0070328 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.7 7.0 GO:0030813 positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.7 6.3 GO:0043320 natural killer cell degranulation(GO:0043320)
0.7 6.9 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.7 6.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.7 6.9 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.7 2.8 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.7 11.0 GO:0006670 sphingosine metabolic process(GO:0006670) diol metabolic process(GO:0034311)
0.7 28.9 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.7 26.6 GO:0033572 transferrin transport(GO:0033572)
0.7 5.5 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.7 16.2 GO:0019731 antibacterial humoral response(GO:0019731)
0.7 19.6 GO:0035082 axoneme assembly(GO:0035082)
0.7 6.7 GO:0032026 response to magnesium ion(GO:0032026)
0.7 0.7 GO:0043366 beta selection(GO:0043366)
0.7 16.8 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.7 17.4 GO:0015695 organic cation transport(GO:0015695)
0.7 2.0 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.7 7.4 GO:0015074 DNA integration(GO:0015074)
0.7 3.3 GO:0060440 trachea formation(GO:0060440)
0.7 2.0 GO:0072092 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.7 9.9 GO:0006833 water transport(GO:0006833)
0.7 3.9 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.7 33.3 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.6 5.8 GO:0002115 store-operated calcium entry(GO:0002115)
0.6 3.9 GO:1901626 regulation of postsynaptic membrane organization(GO:1901626)
0.6 2.6 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.6 4.5 GO:0018344 protein geranylgeranylation(GO:0018344)
0.6 5.2 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.6 14.2 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.6 6.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.6 12.2 GO:0010107 potassium ion import(GO:0010107)
0.6 7.0 GO:0090042 tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.6 5.7 GO:0046641 positive regulation of alpha-beta T cell proliferation(GO:0046641)
0.6 5.0 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.6 5.6 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.6 1.9 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.6 8.6 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.6 2.5 GO:0015811 L-cystine transport(GO:0015811)
0.6 5.4 GO:0031282 regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284)
0.6 26.8 GO:0015701 bicarbonate transport(GO:0015701)
0.6 4.8 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.6 14.9 GO:0000729 DNA double-strand break processing(GO:0000729)
0.6 7.7 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.6 6.5 GO:0006552 leucine catabolic process(GO:0006552)
0.6 2.4 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.6 4.1 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.6 5.9 GO:0002455 humoral immune response mediated by circulating immunoglobulin(GO:0002455)
0.6 8.2 GO:0006111 regulation of gluconeogenesis(GO:0006111)
0.6 17.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.6 8.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.6 9.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.6 3.4 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.6 14.8 GO:0046473 phosphatidic acid metabolic process(GO:0046473)
0.6 35.9 GO:0090630 activation of GTPase activity(GO:0090630)
0.6 2.8 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.6 4.5 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.6 1.1 GO:0035994 response to muscle stretch(GO:0035994)
0.6 5.0 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.6 1.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.5 2.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.5 21.2 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.5 12.5 GO:0045646 regulation of erythrocyte differentiation(GO:0045646)
0.5 4.7 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.5 1.0 GO:0040037 negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037)
0.5 6.2 GO:0072017 distal tubule development(GO:0072017)
0.5 5.1 GO:0048286 lung alveolus development(GO:0048286)
0.5 4.0 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.5 7.0 GO:0032060 bleb assembly(GO:0032060)
0.5 5.0 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.5 3.0 GO:0043217 peripheral nervous system myelin maintenance(GO:0032287) myelin maintenance(GO:0043217)
0.5 4.4 GO:0046697 decidualization(GO:0046697)
0.5 6.4 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.5 7.3 GO:0060612 adipose tissue development(GO:0060612)
0.5 4.3 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.5 6.7 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.5 5.7 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.5 0.5 GO:0003418 growth plate cartilage chondrocyte differentiation(GO:0003418)
0.5 2.4 GO:0071352 cellular response to interleukin-2(GO:0071352)
0.5 2.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.5 8.5 GO:0021854 hypothalamus development(GO:0021854)
0.5 9.9 GO:0006884 cell volume homeostasis(GO:0006884)
0.5 14.5 GO:0045026 plasma membrane fusion(GO:0045026)
0.5 12.2 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.5 28.4 GO:1902476 chloride transmembrane transport(GO:1902476)
0.5 1.9 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.5 16.6 GO:0034067 protein localization to Golgi apparatus(GO:0034067)
0.5 1.4 GO:0051410 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.5 3.6 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.5 7.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.5 27.5 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.4 22.0 GO:0042102 positive regulation of T cell proliferation(GO:0042102)
0.4 4.9 GO:0035855 megakaryocyte development(GO:0035855)
0.4 24.6 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.4 4.0 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.4 11.0 GO:0060411 cardiac septum morphogenesis(GO:0060411)
0.4 5.3 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.4 1.8 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.4 6.1 GO:0000052 citrulline metabolic process(GO:0000052)
0.4 3.1 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.4 4.4 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.4 15.5 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.4 3.0 GO:0080009 mRNA methylation(GO:0080009)
0.4 14.6 GO:0005980 glycogen catabolic process(GO:0005980)
0.4 3.8 GO:0071294 cellular response to zinc ion(GO:0071294)
0.4 8.0 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.4 2.1 GO:0006788 heme oxidation(GO:0006788)
0.4 8.8 GO:0030252 growth hormone secretion(GO:0030252)
0.4 11.6 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.4 14.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.4 11.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.4 1.6 GO:0014827 intestine smooth muscle contraction(GO:0014827)
0.4 8.9 GO:0035455 response to interferon-alpha(GO:0035455)
0.4 10.1 GO:0014823 response to activity(GO:0014823)
0.4 3.6 GO:0008089 anterograde axonal transport(GO:0008089)
0.4 55.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.4 3.5 GO:0001865 NK T cell differentiation(GO:0001865)
0.4 8.4 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.4 5.0 GO:0071305 cellular response to vitamin D(GO:0071305)
0.4 1.5 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.4 12.5 GO:0010863 positive regulation of phospholipase C activity(GO:0010863)
0.4 1.9 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.4 7.1 GO:0001945 lymph vessel development(GO:0001945)
0.4 2.6 GO:0016081 synaptic vesicle docking(GO:0016081)
0.4 5.8 GO:0033599 regulation of mammary gland epithelial cell proliferation(GO:0033599)
0.4 6.2 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.4 10.9 GO:0019730 antimicrobial humoral response(GO:0019730)
0.4 4.3 GO:0060037 pharyngeal system development(GO:0060037)
0.4 6.5 GO:0003334 keratinocyte development(GO:0003334)
0.4 9.3 GO:0021675 nerve development(GO:0021675)
0.4 3.2 GO:0098535 de novo centriole assembly(GO:0098535)
0.4 2.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.4 6.7 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.4 1.1 GO:0045144 meiotic sister chromatid segregation(GO:0045144)
0.4 2.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.3 0.3 GO:0010536 regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536) activation of Janus kinase activity(GO:0042976)
0.3 8.2 GO:0030488 tRNA methylation(GO:0030488)
0.3 4.1 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.3 2.0 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.3 4.9 GO:0006692 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.3 6.8 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.3 6.8 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.3 6.0 GO:0032570 response to progesterone(GO:0032570)
0.3 5.2 GO:0003322 pancreatic A cell development(GO:0003322)
0.3 1.8 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.3 3.0 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.3 3.8 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.3 3.8 GO:0015671 oxygen transport(GO:0015671)
0.3 24.4 GO:0007286 spermatid development(GO:0007286)
0.3 3.8 GO:0002323 natural killer cell activation involved in immune response(GO:0002323)
0.3 8.6 GO:0006400 tRNA modification(GO:0006400)
0.3 3.7 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.3 4.5 GO:0030317 sperm motility(GO:0030317)
0.3 3.9 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.3 2.8 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.3 45.4 GO:0043401 steroid hormone mediated signaling pathway(GO:0043401)
0.3 9.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.3 7.0 GO:1901998 toxin transport(GO:1901998)
0.3 4.5 GO:0014911 positive regulation of smooth muscle cell migration(GO:0014911)
0.3 1.1 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.3 4.2 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.3 4.2 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.3 3.8 GO:0060022 hard palate development(GO:0060022)
0.3 7.4 GO:1904892 regulation of JAK-STAT cascade(GO:0046425) regulation of STAT cascade(GO:1904892)
0.2 1.9 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.2 2.8 GO:0018298 protein-chromophore linkage(GO:0018298)
0.2 3.0 GO:0061756 leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756)
0.2 8.6 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400)
0.2 2.1 GO:0010265 SCF complex assembly(GO:0010265)
0.2 1.1 GO:0015865 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
0.2 4.1 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.2 1.6 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.2 2.9 GO:0007398 ectoderm development(GO:0007398)
0.2 2.2 GO:0010842 retina layer formation(GO:0010842)
0.2 0.8 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.2 2.5 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.2 1.0 GO:0061744 motor behavior(GO:0061744)
0.2 4.9 GO:0002040 sprouting angiogenesis(GO:0002040)
0.2 0.4 GO:0032070 regulation of deoxyribonuclease activity(GO:0032070) regulation of endodeoxyribonuclease activity(GO:0032071)
0.2 1.0 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.2 0.2 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
0.2 3.5 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.2 2.8 GO:0019433 triglyceride catabolic process(GO:0019433)
0.2 1.1 GO:0035063 nuclear speck organization(GO:0035063)
0.2 20.8 GO:0007601 visual perception(GO:0007601)
0.2 0.5 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.2 2.3 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.2 5.0 GO:0006198 cAMP catabolic process(GO:0006198)
0.2 2.9 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.2 4.6 GO:0021762 substantia nigra development(GO:0021762)
0.2 15.0 GO:0050796 regulation of insulin secretion(GO:0050796)
0.2 2.4 GO:0050906 detection of stimulus involved in sensory perception(GO:0050906)
0.2 3.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.2 1.8 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.1 3.3 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 0.7 GO:0038042 dimeric G-protein coupled receptor signaling pathway(GO:0038042)
0.1 1.3 GO:0060325 face morphogenesis(GO:0060325)
0.1 4.3 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.1 1.1 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 2.2 GO:0048873 homeostasis of number of cells within a tissue(GO:0048873)
0.1 0.6 GO:0048596 embryonic camera-type eye morphogenesis(GO:0048596)
0.1 1.0 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 2.6 GO:0070498 interleukin-1-mediated signaling pathway(GO:0070498)
0.1 0.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 1.8 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 4.4 GO:0036297 interstrand cross-link repair(GO:0036297)
0.1 58.7 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.1 1.1 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.1 0.7 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 0.6 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.1 3.0 GO:0000186 activation of MAPKK activity(GO:0000186)
0.1 0.2 GO:0042418 epinephrine metabolic process(GO:0042414) epinephrine biosynthetic process(GO:0042418)
0.1 1.3 GO:0042354 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.1 5.8 GO:0035113 embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
0.1 2.7 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 0.9 GO:0071347 cellular response to interleukin-1(GO:0071347)
0.1 1.3 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 1.7 GO:0010165 response to X-ray(GO:0010165)
0.1 1.0 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 0.8 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 1.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.1 0.1 GO:0042222 interleukin-1 biosynthetic process(GO:0042222) interleukin-1 beta biosynthetic process(GO:0050720)
0.1 0.9 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.1 GO:1903027 regulation of opsonization(GO:1903027)
0.0 0.4 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 1.1 GO:0019233 sensory perception of pain(GO:0019233)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.8 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.3 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.3 GO:0031280 negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
15.4 246.2 GO:0097512 cardiac myofibril(GO:0097512)
11.1 44.5 GO:0005602 complement component C1 complex(GO:0005602)
9.9 29.6 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
9.0 71.6 GO:0060199 clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203)
8.6 25.7 GO:0098831 cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569)
8.2 24.6 GO:0071750 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752)
7.6 68.6 GO:0098845 postsynaptic endosome(GO:0098845)
7.5 135.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
7.5 22.5 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
6.6 39.8 GO:1990682 CSF1-CSF1R complex(GO:1990682)
6.6 32.9 GO:0019815 B cell receptor complex(GO:0019815)
6.4 19.2 GO:0060987 lipid tube(GO:0060987)
6.2 37.3 GO:0045298 tubulin complex(GO:0045298)
5.5 21.9 GO:0033596 TSC1-TSC2 complex(GO:0033596)
5.2 26.2 GO:0032044 DSIF complex(GO:0032044)
5.2 15.6 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
5.1 10.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
4.9 83.0 GO:0033010 paranodal junction(GO:0033010)
4.4 13.3 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
4.2 42.4 GO:0005614 interstitial matrix(GO:0005614)
4.1 20.3 GO:0097513 myosin II filament(GO:0097513)
3.9 73.2 GO:0042613 MHC class II protein complex(GO:0042613)
3.7 26.1 GO:0072687 meiotic spindle(GO:0072687)
3.7 14.9 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
3.6 42.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
3.5 24.5 GO:0030893 meiotic cohesin complex(GO:0030893)
3.5 17.3 GO:1990031 pinceau fiber(GO:1990031)
3.5 17.3 GO:0031674 I band(GO:0031674)
3.4 10.2 GO:0031251 PAN complex(GO:0031251)
3.4 10.2 GO:0005760 gamma DNA polymerase complex(GO:0005760)
3.4 10.1 GO:0031933 telomeric heterochromatin(GO:0031933)
3.3 39.0 GO:0097427 microtubule bundle(GO:0097427)
3.2 12.7 GO:0090533 cation-transporting ATPase complex(GO:0090533)
3.1 22.0 GO:0071439 clathrin complex(GO:0071439)
3.1 68.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
3.0 9.1 GO:0032116 SMC loading complex(GO:0032116)
2.9 17.3 GO:0001940 male pronucleus(GO:0001940)
2.9 23.1 GO:0097433 dense body(GO:0097433)
2.9 5.7 GO:1990584 cardiac Troponin complex(GO:1990584)
2.8 17.0 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
2.8 19.8 GO:0097209 epidermal lamellar body(GO:0097209)
2.7 18.6 GO:1990635 proximal dendrite(GO:1990635)
2.6 47.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
2.6 7.8 GO:0070701 mucus layer(GO:0070701)
2.6 17.9 GO:0043196 varicosity(GO:0043196)
2.5 12.6 GO:0044327 dendritic spine head(GO:0044327)
2.5 19.8 GO:0045179 apical cortex(GO:0045179)
2.5 34.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
2.4 9.8 GO:0005826 actomyosin contractile ring(GO:0005826)
2.4 22.0 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
2.4 125.0 GO:0048786 presynaptic active zone(GO:0048786)
2.3 115.6 GO:0019814 immunoglobulin complex(GO:0019814)
2.3 20.8 GO:0071953 elastic fiber(GO:0071953)
2.3 16.0 GO:0042584 chromaffin granule membrane(GO:0042584)
2.2 11.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
2.1 31.9 GO:0005883 neurofilament(GO:0005883)
2.1 16.6 GO:0000138 Golgi trans cisterna(GO:0000138)
2.1 35.3 GO:0031045 dense core granule(GO:0031045)
2.1 6.2 GO:0097443 sorting endosome(GO:0097443)
2.0 13.9 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
2.0 94.7 GO:0001533 cornified envelope(GO:0001533)
2.0 19.6 GO:0046581 intercellular canaliculus(GO:0046581)
1.9 3.9 GO:0099634 postsynaptic specialization membrane(GO:0099634)
1.9 25.3 GO:0033093 Weibel-Palade body(GO:0033093)
1.9 9.7 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
1.9 5.8 GO:0032009 early phagosome(GO:0032009)
1.9 16.9 GO:0044294 dendritic growth cone(GO:0044294)
1.9 15.0 GO:0005828 kinetochore microtubule(GO:0005828)
1.8 73.6 GO:1902711 GABA-A receptor complex(GO:1902711)
1.8 7.4 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
1.8 28.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
1.7 8.7 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
1.7 10.4 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
1.7 51.9 GO:0031143 pseudopodium(GO:0031143)
1.7 13.8 GO:0035976 AP1 complex(GO:0035976)
1.7 12.1 GO:0036157 outer dynein arm(GO:0036157)
1.7 20.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
1.7 11.9 GO:0061689 tricellular tight junction(GO:0061689)
1.7 6.8 GO:0042272 nuclear RNA export factor complex(GO:0042272)
1.7 6.8 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
1.7 23.4 GO:0043083 synaptic cleft(GO:0043083)
1.7 13.3 GO:0070187 telosome(GO:0070187)
1.7 16.6 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)
1.6 4.9 GO:0097224 sperm connecting piece(GO:0097224)
1.6 56.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
1.6 8.0 GO:0032444 activin responsive factor complex(GO:0032444)
1.6 12.6 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
1.6 36.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
1.6 11.0 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
1.6 7.8 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
1.5 18.4 GO:0097539 ciliary transition fiber(GO:0097539)
1.5 4.6 GO:0036030 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
1.5 4.5 GO:0043293 apoptosome(GO:0043293)
1.5 10.4 GO:0060077 inhibitory synapse(GO:0060077)
1.5 43.2 GO:0032589 neuron projection membrane(GO:0032589)
1.5 26.6 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
1.5 2.9 GO:0033268 node of Ranvier(GO:0033268)
1.5 13.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
1.5 10.2 GO:1990745 EARP complex(GO:1990745)
1.4 4.3 GO:0005899 insulin receptor complex(GO:0005899)
1.4 35.8 GO:0030673 axolemma(GO:0030673)
1.4 49.8 GO:0071565 nBAF complex(GO:0071565)
1.4 16.9 GO:0033270 paranode region of axon(GO:0033270)
1.4 18.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
1.4 13.8 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
1.4 12.3 GO:0044194 cytolytic granule(GO:0044194)
1.4 14.9 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
1.3 4.0 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
1.3 5.3 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
1.3 23.5 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
1.3 205.2 GO:0031225 anchored component of membrane(GO:0031225)
1.3 15.5 GO:0097486 multivesicular body lumen(GO:0097486)
1.3 18.0 GO:0034362 low-density lipoprotein particle(GO:0034362)
1.3 119.5 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
1.3 8.9 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
1.2 11.2 GO:0033391 chromatoid body(GO:0033391)
1.2 23.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
1.2 3.6 GO:0005745 m-AAA complex(GO:0005745)
1.2 25.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
1.2 10.6 GO:1990761 growth cone lamellipodium(GO:1990761)
1.2 3.5 GO:0016938 kinesin I complex(GO:0016938)
1.2 26.8 GO:0001891 phagocytic cup(GO:0001891)
1.1 42.4 GO:0005859 muscle myosin complex(GO:0005859)
1.1 17.1 GO:0097440 apical dendrite(GO:0097440)
1.1 13.6 GO:0008290 F-actin capping protein complex(GO:0008290)
1.1 4.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
1.1 6.7 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
1.1 18.1 GO:0044224 juxtaparanode region of axon(GO:0044224)
1.1 14.9 GO:0048188 Set1C/COMPASS complex(GO:0048188)
1.1 18.0 GO:0016461 unconventional myosin complex(GO:0016461)
1.0 28.2 GO:0042101 T cell receptor complex(GO:0042101)
0.9 46.0 GO:0043198 dendritic shaft(GO:0043198)
0.9 8.4 GO:0042599 lamellar body(GO:0042599)
0.9 1.9 GO:0005797 Golgi medial cisterna(GO:0005797)
0.9 8.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.9 25.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.9 11.4 GO:0005902 microvillus(GO:0005902)
0.9 9.6 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.9 4.3 GO:0089701 U2AF(GO:0089701)
0.9 12.8 GO:0001741 XY body(GO:0001741)
0.8 4.2 GO:0070852 cell body fiber(GO:0070852)
0.8 2.5 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.8 12.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.8 6.5 GO:1905202 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
0.8 23.6 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.8 130.6 GO:0072562 blood microparticle(GO:0072562)
0.8 80.1 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.8 5.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.8 13.5 GO:0097225 sperm midpiece(GO:0097225)
0.8 9.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.8 3.1 GO:0097123 cyclin A1-CDK2 complex(GO:0097123)
0.8 81.2 GO:0043204 perikaryon(GO:0043204)
0.8 30.1 GO:0008305 integrin complex(GO:0008305)
0.8 28.3 GO:0034707 chloride channel complex(GO:0034707)
0.8 11.5 GO:0005861 troponin complex(GO:0005861)
0.8 6.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.7 30.7 GO:0031228 intrinsic component of Golgi membrane(GO:0031228)
0.7 3.7 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.7 13.8 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.7 45.2 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.7 40.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.7 21.0 GO:0005921 gap junction(GO:0005921)
0.7 3.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.7 32.0 GO:0030667 secretory granule membrane(GO:0030667)
0.7 6.7 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.7 6.7 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.7 3.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.7 155.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.7 11.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.6 6.5 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.6 3.9 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.6 19.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.6 4.4 GO:0036021 endolysosome lumen(GO:0036021)
0.6 3.0 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.6 4.1 GO:0060091 kinocilium(GO:0060091)
0.6 12.4 GO:0002080 acrosomal membrane(GO:0002080)
0.6 7.8 GO:0044447 axoneme part(GO:0044447)
0.5 7.6 GO:0005869 dynactin complex(GO:0005869)
0.5 7.6 GO:0000124 SAGA complex(GO:0000124)
0.5 3.2 GO:0060171 stereocilium membrane(GO:0060171)
0.5 19.9 GO:0001917 photoreceptor inner segment(GO:0001917)
0.5 5.7 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.5 35.5 GO:0005796 Golgi lumen(GO:0005796)
0.5 1.5 GO:0097229 sperm end piece(GO:0097229)
0.5 2.0 GO:0005960 glycine cleavage complex(GO:0005960)
0.5 8.4 GO:0005581 collagen trimer(GO:0005581)
0.5 28.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.5 1.9 GO:0000145 exocyst(GO:0000145)
0.5 5.0 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.4 6.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.4 3.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.4 3.0 GO:0042627 chylomicron(GO:0042627)
0.4 2.1 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.4 7.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.4 5.9 GO:0000974 Prp19 complex(GO:0000974)
0.4 13.2 GO:0035861 site of double-strand break(GO:0035861)
0.4 3.3 GO:0072487 MSL complex(GO:0072487)
0.4 5.5 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.4 11.1 GO:0055038 recycling endosome membrane(GO:0055038)
0.3 1.0 GO:0030312 external encapsulating structure(GO:0030312)
0.3 0.3 GO:0070195 growth hormone receptor complex(GO:0070195)
0.3 13.8 GO:0016235 aggresome(GO:0016235)
0.3 5.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.3 61.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.3 9.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.3 6.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.3 44.7 GO:0043025 neuronal cell body(GO:0043025)
0.3 1.8 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.3 11.0 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.3 6.0 GO:0001750 photoreceptor outer segment(GO:0001750)
0.3 1.1 GO:0035838 growing cell tip(GO:0035838) new growing cell tip(GO:0035841)
0.3 21.1 GO:0035579 specific granule membrane(GO:0035579)
0.3 10.9 GO:0005604 basement membrane(GO:0005604)
0.3 1.8 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.3 26.9 GO:0031985 Golgi cisterna(GO:0031985)
0.3 10.5 GO:0031526 brush border membrane(GO:0031526)
0.2 6.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.2 5.3 GO:0051233 spindle midzone(GO:0051233)
0.2 15.1 GO:0005776 autophagosome(GO:0005776)
0.2 20.3 GO:0031514 motile cilium(GO:0031514)
0.2 1.5 GO:0031527 filopodium membrane(GO:0031527)
0.2 3.4 GO:0031082 BLOC complex(GO:0031082)
0.2 20.2 GO:0030018 Z disc(GO:0030018)
0.2 2.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.2 11.2 GO:0043202 lysosomal lumen(GO:0043202)
0.1 601.2 GO:0016021 integral component of membrane(GO:0016021)
0.1 7.6 GO:0043197 dendritic spine(GO:0043197)
0.1 122.1 GO:0005615 extracellular space(GO:0005615)
0.1 1.4 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 8.7 GO:0030426 growth cone(GO:0030426)
0.1 0.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 7.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 2.8 GO:0044297 cell body(GO:0044297)
0.1 0.6 GO:0005833 hemoglobin complex(GO:0005833)
0.1 3.4 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.1 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
16.6 83.2 GO:0004522 ribonuclease A activity(GO:0004522)
14.2 42.7 GO:0032093 SAM domain binding(GO:0032093)
14.2 56.8 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
11.5 34.6 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
11.4 45.6 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
9.7 48.4 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
9.6 86.0 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
9.3 37.3 GO:0099609 microtubule lateral binding(GO:0099609)
9.3 37.2 GO:0016880 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
8.5 25.5 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
8.4 33.8 GO:0004773 steryl-sulfatase activity(GO:0004773)
8.2 57.5 GO:0042289 MHC class II protein binding(GO:0042289)
8.0 239.8 GO:0005212 structural constituent of eye lens(GO:0005212)
8.0 39.8 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
7.5 22.5 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
7.4 22.3 GO:0016497 substance K receptor activity(GO:0016497)
7.2 21.6 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
7.0 27.8 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
6.9 20.7 GO:1904599 advanced glycation end-product binding(GO:1904599)
6.8 47.3 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
6.5 38.9 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
6.4 6.4 GO:0050682 AF-2 domain binding(GO:0050682)
6.3 25.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
6.2 18.5 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
6.1 36.8 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
6.1 67.1 GO:0032051 clathrin light chain binding(GO:0032051)
6.1 42.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
6.0 24.2 GO:0097001 ceramide binding(GO:0097001)
6.0 36.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
6.0 17.9 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
5.9 35.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
5.9 53.0 GO:0031685 adenosine receptor binding(GO:0031685)
5.8 17.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
5.6 22.5 GO:0035939 microsatellite binding(GO:0035939)
5.4 16.2 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
5.1 10.2 GO:0016890 site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890)
5.0 60.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
5.0 35.1 GO:0030492 hemoglobin binding(GO:0030492)
4.9 39.5 GO:0015185 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
4.9 19.7 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
4.9 24.6 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
4.7 14.2 GO:0004878 complement component C5a receptor activity(GO:0004878)
4.7 9.3 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
4.5 18.1 GO:0070051 fibrinogen binding(GO:0070051)
4.5 36.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
4.3 8.6 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
4.2 25.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
4.2 25.2 GO:0032038 myosin II heavy chain binding(GO:0032038)
4.1 12.4 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
4.1 24.6 GO:0051373 FATZ binding(GO:0051373)
4.0 24.1 GO:0030172 troponin C binding(GO:0030172)
3.9 27.5 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
3.8 11.4 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
3.8 49.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
3.8 127.8 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
3.7 11.0 GO:0070052 collagen V binding(GO:0070052)
3.6 18.2 GO:0004991 parathyroid hormone receptor activity(GO:0004991)
3.6 51.0 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
3.6 10.9 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
3.6 50.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
3.6 28.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
3.6 21.4 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
3.5 10.5 GO:0016833 oxo-acid-lyase activity(GO:0016833)
3.5 20.9 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
3.3 13.4 GO:0070095 fructose-6-phosphate binding(GO:0070095)
3.3 16.5 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
3.3 9.9 GO:0070735 protein-glycine ligase activity(GO:0070735)
3.3 16.4 GO:0045174 glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
3.3 55.5 GO:0019864 IgG binding(GO:0019864)
3.2 12.8 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
3.2 12.6 GO:0004769 steroid delta-isomerase activity(GO:0004769)
3.1 28.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
3.1 34.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
3.1 28.0 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
3.1 9.2 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
3.0 21.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
3.0 36.3 GO:0003996 acyl-CoA ligase activity(GO:0003996)
3.0 9.0 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
3.0 30.0 GO:0015386 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
3.0 8.9 GO:0004796 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
2.9 8.7 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
2.9 28.7 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
2.8 11.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
2.8 16.7 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
2.7 10.9 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
2.7 21.5 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
2.6 10.5 GO:1904493 Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493)
2.6 56.8 GO:0019104 DNA N-glycosylase activity(GO:0019104)
2.6 12.9 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
2.6 41.0 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
2.5 12.5 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
2.5 35.0 GO:0003691 double-stranded telomeric DNA binding(GO:0003691)
2.4 26.9 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
2.4 26.7 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
2.4 33.8 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
2.4 7.2 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
2.4 7.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
2.3 9.4 GO:0015254 glycerol channel activity(GO:0015254)
2.3 7.0 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
2.3 20.8 GO:0070697 activin receptor binding(GO:0070697)
2.3 25.1 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
2.3 9.1 GO:0004461 lactose synthase activity(GO:0004461)
2.3 70.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
2.3 69.8 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
2.2 40.3 GO:0038191 neuropilin binding(GO:0038191)
2.2 8.9 GO:0008281 sulfonylurea receptor activity(GO:0008281)
2.2 8.9 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
2.2 11.2 GO:0004370 glycerol kinase activity(GO:0004370)
2.2 20.1 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117)
2.2 10.9 GO:0004994 somatostatin receptor activity(GO:0004994)
2.2 6.5 GO:0005055 laminin receptor activity(GO:0005055)
2.2 6.5 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
2.2 30.3 GO:0046790 virion binding(GO:0046790)
2.2 8.6 GO:0004341 gluconolactonase activity(GO:0004341)
2.2 129.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)
2.1 51.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
2.1 14.9 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
2.1 12.4 GO:0004359 glutaminase activity(GO:0004359)
2.1 22.6 GO:0051525 NFAT protein binding(GO:0051525)
2.1 43.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
2.0 32.5 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
2.0 12.2 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
2.0 4.1 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
2.0 12.0 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
2.0 6.0 GO:0035375 zymogen binding(GO:0035375)
2.0 9.9 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
2.0 5.9 GO:0030158 protein xylosyltransferase activity(GO:0030158)
1.9 29.0 GO:0004985 opioid receptor activity(GO:0004985)
1.9 36.6 GO:0048156 tau protein binding(GO:0048156)
1.9 119.1 GO:0030507 spectrin binding(GO:0030507)
1.9 5.7 GO:0031013 troponin I binding(GO:0031013)
1.9 13.3 GO:0000182 rDNA binding(GO:0000182)
1.9 74.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
1.9 34.1 GO:0004089 carbonate dehydratase activity(GO:0004089)
1.9 18.9 GO:0008131 primary amine oxidase activity(GO:0008131)
1.9 30.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
1.9 9.4 GO:0050436 microfibril binding(GO:0050436)
1.9 5.7 GO:0004047 aminomethyltransferase activity(GO:0004047)
1.9 5.6 GO:0003680 AT DNA binding(GO:0003680)
1.9 104.1 GO:0017080 sodium channel regulator activity(GO:0017080)
1.9 3.7 GO:0008142 oxysterol binding(GO:0008142)
1.8 7.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
1.8 25.8 GO:0004707 MAP kinase activity(GO:0004707)
1.8 10.9 GO:0004882 androgen receptor activity(GO:0004882)
1.8 32.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
1.8 3.6 GO:0004995 tachykinin receptor activity(GO:0004995)
1.8 7.2 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
1.8 5.3 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
1.8 28.1 GO:0043522 leucine zipper domain binding(GO:0043522)
1.8 3.5 GO:0042806 fucose binding(GO:0042806)
1.7 45.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
1.7 5.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
1.7 41.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.7 15.2 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
1.7 5.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
1.7 6.7 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
1.7 21.8 GO:0019865 immunoglobulin binding(GO:0019865)
1.7 8.3 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
1.7 13.3 GO:0004111 creatine kinase activity(GO:0004111)
1.7 6.6 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
1.7 5.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
1.6 24.7 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
1.6 4.9 GO:0047325 inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835)
1.6 4.8 GO:0004998 transferrin receptor activity(GO:0004998)
1.6 14.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
1.6 17.5 GO:0050811 GABA receptor binding(GO:0050811)
1.6 12.7 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
1.6 14.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
1.6 25.3 GO:0070411 I-SMAD binding(GO:0070411)
1.6 7.9 GO:0043546 molybdopterin cofactor binding(GO:0043546)
1.6 9.5 GO:0004614 phosphoglucomutase activity(GO:0004614)
1.5 10.8 GO:0004797 deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797)
1.5 9.2 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
1.5 18.4 GO:0038132 neuregulin binding(GO:0038132)
1.5 7.5 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.5 13.5 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
1.5 3.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
1.5 44.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
1.5 5.9 GO:0005412 glucose:sodium symporter activity(GO:0005412)
1.5 5.9 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
1.5 8.8 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
1.4 181.1 GO:0003707 steroid hormone receptor activity(GO:0003707)
1.4 12.9 GO:0034235 GPI anchor binding(GO:0034235)
1.4 5.7 GO:0002046 opsin binding(GO:0002046)
1.4 5.7 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
1.4 40.0 GO:0050321 tau-protein kinase activity(GO:0050321)
1.4 396.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
1.4 8.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
1.4 5.7 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
1.4 8.5 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
1.4 18.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
1.4 4.2 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
1.4 7.0 GO:0042610 CD8 receptor binding(GO:0042610)
1.4 4.2 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
1.4 11.2 GO:0042609 CD4 receptor binding(GO:0042609)
1.4 8.3 GO:0039552 RIG-I binding(GO:0039552)
1.4 10.9 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
1.4 15.0 GO:0004645 phosphorylase activity(GO:0004645)
1.4 14.9 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
1.4 4.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
1.3 24.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
1.3 10.8 GO:0016015 morphogen activity(GO:0016015)
1.3 21.4 GO:0016805 dipeptidase activity(GO:0016805)
1.3 10.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
1.3 19.8 GO:0043560 insulin receptor substrate binding(GO:0043560)
1.3 3.9 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
1.3 7.8 GO:0043237 laminin-1 binding(GO:0043237)
1.3 19.6 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
1.3 6.5 GO:0033695 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
1.3 44.9 GO:0017075 syntaxin-1 binding(GO:0017075)
1.2 3.7 GO:0004980 melanocyte-stimulating hormone receptor activity(GO:0004980)
1.2 44.9 GO:0004890 GABA-A receptor activity(GO:0004890)
1.2 7.5 GO:0004046 aminoacylase activity(GO:0004046)
1.2 12.4 GO:0005549 odorant binding(GO:0005549)
1.2 19.7 GO:0008320 protein transmembrane transporter activity(GO:0008320)
1.2 8.6 GO:0070891 lipoteichoic acid binding(GO:0070891)
1.2 22.0 GO:0005024 transforming growth factor beta-activated receptor activity(GO:0005024)
1.2 22.0 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
1.2 4.9 GO:0015220 choline transmembrane transporter activity(GO:0015220)
1.2 14.6 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
1.2 4.8 GO:0042923 neuropeptide binding(GO:0042923)
1.2 4.7 GO:0004668 protein-arginine deiminase activity(GO:0004668)
1.2 15.4 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
1.2 7.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
1.2 25.9 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
1.2 9.3 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
1.2 4.6 GO:0004925 prolactin receptor activity(GO:0004925)
1.2 17.3 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
1.1 3.4 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
1.1 4.5 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
1.1 10.1 GO:0051425 PTB domain binding(GO:0051425)
1.1 4.5 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
1.1 13.4 GO:0031432 titin binding(GO:0031432)
1.1 6.7 GO:0004689 phosphorylase kinase activity(GO:0004689)
1.1 9.9 GO:0043426 MRF binding(GO:0043426)
1.1 4.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
1.1 22.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
1.1 21.6 GO:0005522 profilin binding(GO:0005522)
1.1 3.2 GO:0004967 glucagon receptor activity(GO:0004967)
1.1 13.8 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
1.1 8.5 GO:0032794 GTPase activating protein binding(GO:0032794)
1.1 14.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
1.1 9.5 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
1.1 9.5 GO:0097322 7SK snRNA binding(GO:0097322)
1.0 3.1 GO:0017129 triglyceride binding(GO:0017129)
1.0 3.0 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
1.0 11.0 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
1.0 15.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
1.0 51.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
1.0 9.0 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
1.0 42.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
1.0 4.9 GO:0004905 type I interferon receptor activity(GO:0004905)
1.0 7.8 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
1.0 13.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
1.0 9.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
1.0 12.5 GO:0036374 glutathione hydrolase activity(GO:0036374)
1.0 27.7 GO:0008066 glutamate receptor activity(GO:0008066)
1.0 6.7 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.9 12.3 GO:0070700 BMP receptor binding(GO:0070700)
0.9 12.3 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.9 15.0 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.9 6.5 GO:0004075 biotin carboxylase activity(GO:0004075)
0.9 9.3 GO:0032027 myosin light chain binding(GO:0032027)
0.9 15.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.9 3.7 GO:0097108 hedgehog family protein binding(GO:0097108)
0.9 15.6 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.9 22.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.9 14.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.9 20.9 GO:0043014 alpha-tubulin binding(GO:0043014)
0.9 4.5 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.9 8.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.9 6.3 GO:0019826 oxygen sensor activity(GO:0019826)
0.9 16.9 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.9 6.2 GO:0001225 RNA polymerase II transcription cofactor binding(GO:0001224) RNA polymerase II transcription coactivator binding(GO:0001225)
0.9 5.3 GO:0032052 bile acid binding(GO:0032052)
0.9 9.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.9 73.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.9 82.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.9 19.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.8 5.9 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.8 4.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.8 5.0 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.8 6.6 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697) G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.8 98.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.8 8.2 GO:0001223 transcription coactivator binding(GO:0001223)
0.8 4.9 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.8 9.7 GO:0032395 MHC class II receptor activity(GO:0032395)
0.8 10.5 GO:0019841 retinol binding(GO:0019841)
0.8 3.2 GO:0003951 NAD+ kinase activity(GO:0003951)
0.8 2.3 GO:0047783 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.8 5.4 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.8 18.6 GO:0070402 NADPH binding(GO:0070402)
0.8 5.4 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.8 52.2 GO:0070888 E-box binding(GO:0070888)
0.8 3.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.8 15.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.7 6.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.7 2.2 GO:0098640 integrin binding involved in cell-matrix adhesion(GO:0098640)
0.7 6.6 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.7 10.2 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.7 7.9 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.7 10.0 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.7 10.0 GO:0032183 SUMO binding(GO:0032183)
0.7 8.5 GO:0005344 oxygen transporter activity(GO:0005344)
0.7 6.4 GO:0043274 phospholipase binding(GO:0043274)
0.7 16.3 GO:0070403 NAD+ binding(GO:0070403)
0.7 18.4 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.7 4.2 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.7 4.2 GO:0017060 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060)
0.7 10.6 GO:0019992 diacylglycerol binding(GO:0019992)
0.7 2.1 GO:0019150 D-ribulokinase activity(GO:0019150)
0.7 7.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.7 9.8 GO:0000146 microfilament motor activity(GO:0000146)
0.7 6.3 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.7 27.0 GO:0042169 SH2 domain binding(GO:0042169)
0.7 222.9 GO:0005096 GTPase activator activity(GO:0005096)
0.7 4.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.7 8.2 GO:0017081 chloride channel regulator activity(GO:0017081)
0.7 3.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.7 15.6 GO:0004623 phospholipase A2 activity(GO:0004623)
0.7 23.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.7 2.7 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.6 3.9 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.6 22.7 GO:0005158 insulin receptor binding(GO:0005158)
0.6 23.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.6 3.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.6 10.5 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.6 4.3 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.6 8.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.6 2.4 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.6 24.9 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.6 18.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.6 2.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.6 15.1 GO:0042605 peptide antigen binding(GO:0042605)
0.6 4.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.6 1.7 GO:0036505 prosaposin receptor activity(GO:0036505)
0.6 14.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.6 8.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.6 5.6 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.6 3.3 GO:0036122 BMP binding(GO:0036122)
0.6 13.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.6 3.9 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.6 8.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.6 3.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.5 13.1 GO:0070840 dynein complex binding(GO:0070840)
0.5 3.3 GO:0070569 uridylyltransferase activity(GO:0070569)
0.5 14.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.5 16.0 GO:0071837 HMG box domain binding(GO:0071837)
0.5 4.8 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.5 5.3 GO:0015250 water channel activity(GO:0015250)
0.5 3.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.5 3.6 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.5 31.7 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820)
0.5 3.1 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.5 10.1 GO:0000400 four-way junction DNA binding(GO:0000400)
0.5 3.5 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.5 6.0 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.5 34.6 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.5 5.0 GO:0031014 troponin T binding(GO:0031014)
0.5 19.2 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.5 2.5 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.5 6.9 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.5 2.4 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.5 5.8 GO:0035325 Toll-like receptor binding(GO:0035325)
0.5 3.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.5 5.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.5 5.0 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.5 3.2 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.5 5.0 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.4 13.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.4 2.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.4 2.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.4 8.3 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.4 7.0 GO:0031490 chromatin DNA binding(GO:0031490)
0.4 30.9 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.4 10.4 GO:0005521 lamin binding(GO:0005521)
0.4 4.8 GO:0008527 taste receptor activity(GO:0008527)
0.4 10.5 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.4 6.5 GO:0005542 folic acid binding(GO:0005542)
0.4 3.1 GO:0050693 LBD domain binding(GO:0050693)
0.4 1.5 GO:0005163 nerve growth factor receptor binding(GO:0005163)
0.4 35.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.4 1.1 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.4 4.6 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.4 4.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.3 6.8 GO:0032451 demethylase activity(GO:0032451)
0.3 6.8 GO:0097109 neuroligin family protein binding(GO:0097109)
0.3 2.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 7.7 GO:0033613 activating transcription factor binding(GO:0033613)
0.3 1.6 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.3 1.9 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.3 1.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.3 7.3 GO:0008081 phosphoric diester hydrolase activity(GO:0008081)
0.3 3.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.3 24.0 GO:0017048 Rho GTPase binding(GO:0017048)
0.3 2.3 GO:0031404 chloride ion binding(GO:0031404)
0.3 2.1 GO:0045159 myosin II binding(GO:0045159)
0.3 1.6 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.3 3.9 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.3 3.8 GO:0005132 type I interferon receptor binding(GO:0005132)
0.2 3.3 GO:0005109 frizzled binding(GO:0005109)
0.2 15.1 GO:0019905 syntaxin binding(GO:0019905)
0.2 2.3 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.2 8.3 GO:0017069 snRNA binding(GO:0017069)
0.2 3.7 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 19.9 GO:0020037 heme binding(GO:0020037)
0.2 6.1 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.2 8.6 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.2 3.7 GO:0070412 R-SMAD binding(GO:0070412)
0.2 1.5 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.2 1.1 GO:0005497 androgen binding(GO:0005497)
0.2 1.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 5.7 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 6.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.2 2.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.2 4.4 GO:0030331 estrogen receptor binding(GO:0030331)
0.2 2.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.2 1.4 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.2 3.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.2 4.0 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.2 0.7 GO:0004948 calcitonin receptor activity(GO:0004948)
0.2 6.3 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.2 1.5 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 18.6 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.2 5.0 GO:0019894 kinesin binding(GO:0019894)
0.2 5.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 3.0 GO:0017171 serine hydrolase activity(GO:0017171)
0.2 2.2 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 1.1 GO:0005243 gap junction channel activity(GO:0005243)
0.1 8.1 GO:0005179 hormone activity(GO:0005179)
0.1 2.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.1 4.2 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 2.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 3.1 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 8.9 GO:0047485 protein N-terminus binding(GO:0047485)
0.1 3.6 GO:0030332 cyclin binding(GO:0030332)
0.1 3.1 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.1 0.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 1.0 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 3.1 GO:0032934 sterol binding(GO:0032934)
0.1 1.1 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 35.4 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 0.3 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.1 1.0 GO:0031005 filamin binding(GO:0031005)
0.1 3.4 GO:0016209 antioxidant activity(GO:0016209)
0.1 0.3 GO:0008948 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.0 60.3 GO:0003700 nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700)
0.0 0.3 GO:0032393 MHC class I receptor activity(GO:0032393)
0.0 0.8 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.0 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.4 GO:0005343 organic acid:sodium symporter activity(GO:0005343)
0.0 0.3 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
10.0 10.0 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
2.8 78.7 PID S1P S1P4 PATHWAY S1P4 pathway
1.8 102.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
1.6 66.5 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
1.5 48.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
1.5 58.6 PID RAS PATHWAY Regulation of Ras family activation
1.4 18.4 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
1.4 66.9 ST ADRENERGIC Adrenergic Pathway
1.3 12.1 PID NECTIN PATHWAY Nectin adhesion pathway
1.3 27.2 PID FAS PATHWAY FAS (CD95) signaling pathway
1.3 21.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
1.3 55.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
1.2 4.7 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
1.1 6.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
1.1 13.5 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
1.1 23.9 PID AVB3 OPN PATHWAY Osteopontin-mediated events
1.0 8.2 ST JAK STAT PATHWAY Jak-STAT Pathway
1.0 13.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
1.0 14.0 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.9 18.1 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.9 46.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.9 19.2 PID CONE PATHWAY Visual signal transduction: Cones
0.9 16.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.8 21.6 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.8 34.7 PID REELIN PATHWAY Reelin signaling pathway
0.8 7.0 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.8 28.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.7 4.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.7 11.5 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.7 36.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.7 15.3 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.7 35.5 PID RHOA PATHWAY RhoA signaling pathway
0.7 14.9 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.7 23.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.6 4.9 ST G ALPHA I PATHWAY G alpha i Pathway
0.6 17.6 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.6 15.6 PID CD40 PATHWAY CD40/CD40L signaling
0.6 10.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.6 10.2 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.6 9.0 PID IL27 PATHWAY IL27-mediated signaling events
0.6 15.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.6 5.1 PID S1P S1P3 PATHWAY S1P3 pathway
0.5 39.9 PID LKB1 PATHWAY LKB1 signaling events
0.5 9.2 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.5 10.2 PID IFNG PATHWAY IFN-gamma pathway
0.5 7.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.5 12.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.5 9.5 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.5 18.4 PID ARF6 PATHWAY Arf6 signaling events
0.5 25.2 PID FANCONI PATHWAY Fanconi anemia pathway
0.5 38.4 PID RHOA REG PATHWAY Regulation of RhoA activity
0.5 11.3 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.5 6.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.5 11.2 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.5 15.5 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.5 2.0 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.5 7.8 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.5 16.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.5 24.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.5 26.1 PID FGF PATHWAY FGF signaling pathway
0.5 15.4 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.5 19.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.5 7.3 PID EPO PATHWAY EPO signaling pathway
0.4 18.1 PID PI3KCI PATHWAY Class I PI3K signaling events
0.4 10.9 PID INSULIN PATHWAY Insulin Pathway
0.4 3.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.4 24.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.4 20.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.4 3.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.4 2.7 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.4 10.6 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.4 36.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.4 7.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.3 8.7 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.3 3.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.3 7.1 PID TNF PATHWAY TNF receptor signaling pathway
0.3 6.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 4.7 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.3 68.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.3 5.6 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.3 53.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3 8.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.3 71.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.3 3.4 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.2 5.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.2 7.7 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.2 3.0 PID IL3 PATHWAY IL3-mediated signaling events
0.2 2.2 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.2 3.8 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.2 0.8 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 7.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 3.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 2.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 3.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 1.5 PID BARD1 PATHWAY BARD1 signaling events
0.1 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.1 0.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.1 2.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 1.3 PID ALK2 PATHWAY ALK2 signaling events
0.1 0.7 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 0.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 0.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.0 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.1 PID AP1 PATHWAY AP-1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 10.2 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
4.6 18.4 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
4.1 77.8 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
3.4 6.8 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
3.2 106.0 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
3.2 6.3 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
2.9 79.2 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
2.8 11.1 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
2.7 35.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
2.6 33.8 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
2.5 65.9 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
2.4 48.7 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
2.4 45.3 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
2.4 7.1 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
2.3 55.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
2.3 61.8 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
2.3 45.5 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
2.2 8.9 REACTOME SHC MEDIATED SIGNALLING Genes involved in SHC-mediated signalling
2.1 34.1 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
2.1 48.3 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
2.0 2.0 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
2.0 113.2 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
1.9 33.0 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
1.9 29.0 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
1.8 9.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
1.7 7.0 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
1.7 13.3 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
1.6 55.8 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
1.6 35.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
1.5 64.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
1.5 43.0 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
1.5 187.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
1.5 34.6 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
1.5 22.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
1.5 31.5 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
1.5 26.6 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
1.5 49.4 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
1.5 53.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
1.4 25.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
1.4 27.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
1.3 9.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
1.3 46.8 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
1.3 64.9 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
1.3 60.5 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
1.3 12.7 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
1.3 57.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
1.2 17.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
1.2 19.9 REACTOME COMMON PATHWAY Genes involved in Common Pathway
1.2 29.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
1.2 28.0 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
1.2 16.8 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
1.2 73.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
1.1 6.8 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
1.1 28.1 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
1.1 14.4 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
1.0 19.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
1.0 20.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
1.0 199.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
1.0 26.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
1.0 3.9 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
1.0 5.9 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.9 12.7 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.9 18.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.9 16.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.9 10.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.8 24.6 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.8 6.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.8 27.5 REACTOME AMYLOIDS Genes involved in Amyloids
0.7 10.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.7 4.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.7 6.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.7 18.9 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.7 41.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.7 11.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.7 25.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.7 8.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.7 61.9 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.7 8.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.7 15.0 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.7 9.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.6 12.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.6 14.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.6 34.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.6 10.8 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.6 18.1 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.6 14.2 REACTOME CIRCADIAN CLOCK Genes involved in Circadian Clock
0.6 25.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.6 2.2 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.5 17.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.5 38.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.5 9.3 REACTOME DEFENSINS Genes involved in Defensins
0.5 20.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.5 9.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.5 14.7 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.5 10.6 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.5 6.0 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.5 13.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.5 6.2 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.5 6.6 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.5 14.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.5 8.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.4 9.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.4 15.0 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.4 7.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.4 37.2 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.4 11.7 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.4 7.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.4 8.7 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.4 2.7 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.4 69.4 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.4 3.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.4 10.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.4 30.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.4 27.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.4 5.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.3 8.0 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.3 6.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.3 9.3 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.3 22.4 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.3 6.6 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.3 6.4 REACTOME IL 3 5 AND GM CSF SIGNALING Genes involved in Interleukin-3, 5 and GM-CSF signaling
0.3 6.6 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.3 1.8 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.2 3.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.2 8.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 7.5 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.2 0.9 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.2 13.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 4.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.2 1.1 REACTOME SHC MEDIATED CASCADE Genes involved in SHC-mediated cascade
0.2 0.8 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 4.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 4.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 2.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 29.2 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.1 1.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 10.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 2.0 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.1 2.8 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.7 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 1.5 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.1 2.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix