Project
avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
Navigation
Downloads
Results for EBF1
Z-value: 12.22
Motif logo
Transcription factors associated with EBF1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
EBF1
|
ENSG00000164330.17 | EBF1 |
Activity profile of EBF1 motif
Sorted Z-values of EBF1 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of EBF1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 18.2 | 54.5 | GO:1904395 | positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) |
| 16.0 | 47.9 | GO:0042137 | sequestering of neurotransmitter(GO:0042137) |
| 15.8 | 47.3 | GO:0071139 | resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140) |
| 14.8 | 88.7 | GO:0010731 | protein glutathionylation(GO:0010731) regulation of protein glutathionylation(GO:0010732) negative regulation of protein glutathionylation(GO:0010734) |
| 14.0 | 42.0 | GO:0035691 | macrophage migration inhibitory factor signaling pathway(GO:0035691) |
| 13.8 | 41.3 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) |
| 12.6 | 214.6 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 12.3 | 37.0 | GO:1904692 | positive regulation of type B pancreatic cell proliferation(GO:1904692) |
| 11.8 | 35.5 | GO:0051946 | regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920) |
| 10.8 | 43.3 | GO:0002357 | defense response to tumor cell(GO:0002357) |
| 10.4 | 31.1 | GO:0001869 | regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869) |
| 9.9 | 39.8 | GO:1902228 | positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) mammary gland fat development(GO:0060611) positive regulation of macrophage colony-stimulating factor signaling pathway(GO:1902228) positive regulation of response to macrophage colony-stimulating factor(GO:1903971) positive regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903974) positive regulation of microglial cell migration(GO:1904141) |
| 9.4 | 28.3 | GO:0007181 | transforming growth factor beta receptor complex assembly(GO:0007181) |
| 9.4 | 56.4 | GO:0030644 | cellular chloride ion homeostasis(GO:0030644) |
| 9.3 | 37.2 | GO:0006542 | glutamine biosynthetic process(GO:0006542) |
| 8.7 | 26.1 | GO:1902769 | regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246) |
| 8.6 | 25.7 | GO:0099526 | presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526) |
| 8.4 | 58.6 | GO:0032100 | positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) |
| 8.1 | 56.8 | GO:0045007 | depurination(GO:0045007) |
| 7.6 | 68.6 | GO:0098887 | neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) |
| 7.6 | 30.3 | GO:0046968 | peptide antigen transport(GO:0046968) |
| 7.5 | 37.3 | GO:0090258 | negative regulation of mitochondrial fission(GO:0090258) |
| 7.0 | 28.0 | GO:1901339 | regulation of store-operated calcium channel activity(GO:1901339) |
| 6.9 | 20.8 | GO:1903279 | regulation of calcium:sodium antiporter activity(GO:1903279) positive regulation of calcium:sodium antiporter activity(GO:1903281) |
| 6.9 | 20.7 | GO:1904603 | regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904596) negative regulation of connective tissue replacement involved in inflammatory response wound healing(GO:1904597) regulation of advanced glycation end-product receptor activity(GO:1904603) negative regulation of advanced glycation end-product receptor activity(GO:1904604) negative regulation of connective tissue replacement(GO:1905204) |
| 6.6 | 33.0 | GO:0006154 | adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103) |
| 6.6 | 19.7 | GO:0046878 | positive regulation of saliva secretion(GO:0046878) |
| 6.5 | 19.5 | GO:0048213 | Golgi vesicle prefusion complex stabilization(GO:0048213) |
| 6.4 | 19.2 | GO:0060988 | lipid tube assembly(GO:0060988) |
| 6.1 | 12.2 | GO:2001025 | positive regulation of response to drug(GO:2001025) |
| 6.1 | 42.6 | GO:0051013 | microtubule severing(GO:0051013) |
| 5.9 | 70.3 | GO:0051612 | negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612) |
| 5.8 | 17.4 | GO:0050760 | negative regulation of thymidylate synthase biosynthetic process(GO:0050760) |
| 5.8 | 23.2 | GO:0035627 | ceramide transport(GO:0035627) |
| 5.8 | 23.2 | GO:0033686 | positive regulation of luteinizing hormone secretion(GO:0033686) |
| 5.8 | 23.0 | GO:0018199 | peptidyl-glutamine modification(GO:0018199) |
| 5.7 | 11.5 | GO:0071284 | cellular response to lead ion(GO:0071284) |
| 5.7 | 22.8 | GO:0010430 | fatty acid omega-oxidation(GO:0010430) |
| 5.7 | 22.7 | GO:0009182 | purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) |
| 5.6 | 22.3 | GO:0035106 | operant conditioning(GO:0035106) |
| 5.5 | 21.8 | GO:0099558 | maintenance of synapse structure(GO:0099558) |
| 5.4 | 21.6 | GO:0015855 | pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823) |
| 5.4 | 16.1 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
| 5.3 | 15.9 | GO:0072675 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
| 5.3 | 15.9 | GO:1902595 | regulation of DNA replication origin binding(GO:1902595) |
| 5.3 | 21.1 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
| 5.2 | 15.7 | GO:0010958 | G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) regulation of amino acid import(GO:0010958) response to muscle activity involved in regulation of muscle adaptation(GO:0014873) |
| 5.2 | 56.8 | GO:0006285 | base-excision repair, AP site formation(GO:0006285) |
| 5.1 | 20.6 | GO:1905224 | clathrin-coated pit assembly(GO:1905224) |
| 5.1 | 25.4 | GO:0044375 | regulation of peroxisome size(GO:0044375) |
| 5.0 | 15.1 | GO:0002461 | tolerance induction dependent upon immune response(GO:0002461) |
| 5.0 | 15.1 | GO:0002892 | type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892) |
| 5.0 | 15.0 | GO:0030241 | skeletal muscle myosin thick filament assembly(GO:0030241) |
| 5.0 | 5.0 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
| 4.9 | 9.8 | GO:0035973 | aggrephagy(GO:0035973) |
| 4.9 | 24.6 | GO:2001295 | malonyl-CoA biosynthetic process(GO:2001295) |
| 4.8 | 38.8 | GO:0070236 | regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 4.8 | 38.5 | GO:0032534 | regulation of microvillus assembly(GO:0032534) |
| 4.8 | 43.1 | GO:0002175 | protein localization to paranode region of axon(GO:0002175) |
| 4.7 | 14.2 | GO:0038178 | complement component C5a signaling pathway(GO:0038178) |
| 4.7 | 47.0 | GO:0001766 | membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580) |
| 4.7 | 14.0 | GO:0060032 | notochord regression(GO:0060032) |
| 4.6 | 4.6 | GO:1902219 | regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219) |
| 4.5 | 125.7 | GO:0032012 | regulation of ARF protein signal transduction(GO:0032012) |
| 4.4 | 62.0 | GO:0060371 | regulation of atrial cardiac muscle cell membrane depolarization(GO:0060371) |
| 4.4 | 13.3 | GO:0048294 | negative regulation of isotype switching to IgE isotypes(GO:0048294) |
| 4.4 | 13.2 | GO:0005988 | lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) |
| 4.4 | 22.0 | GO:0032525 | somite rostral/caudal axis specification(GO:0032525) |
| 4.4 | 13.2 | GO:0061027 | umbilical cord morphogenesis(GO:0036304) umbilical cord development(GO:0061027) |
| 4.4 | 30.7 | GO:1900113 | negative regulation of histone H3-K9 trimethylation(GO:1900113) |
| 4.4 | 13.2 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) |
| 4.4 | 13.1 | GO:1904640 | response to methionine(GO:1904640) |
| 4.3 | 13.0 | GO:0048105 | establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) |
| 4.3 | 12.9 | GO:0032792 | negative regulation of CREB transcription factor activity(GO:0032792) |
| 4.3 | 17.2 | GO:0060741 | prostate gland stromal morphogenesis(GO:0060741) |
| 4.3 | 42.8 | GO:0043045 | DNA methylation involved in embryo development(GO:0043045) changes to DNA methylation involved in embryo development(GO:1901538) |
| 4.3 | 68.2 | GO:0048172 | regulation of short-term neuronal synaptic plasticity(GO:0048172) |
| 4.2 | 29.7 | GO:0070560 | protein secretion by platelet(GO:0070560) |
| 4.2 | 16.9 | GO:0045409 | negative regulation of interleukin-6 biosynthetic process(GO:0045409) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
| 4.2 | 12.6 | GO:0051939 | gamma-aminobutyric acid import(GO:0051939) |
| 4.2 | 21.0 | GO:1903385 | regulation of homophilic cell adhesion(GO:1903385) |
| 4.2 | 20.9 | GO:1904306 | regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306) |
| 4.2 | 25.0 | GO:0000189 | MAPK import into nucleus(GO:0000189) |
| 4.2 | 16.6 | GO:0072369 | regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369) |
| 4.1 | 12.3 | GO:0009386 | translational attenuation(GO:0009386) |
| 4.1 | 16.3 | GO:1904020 | regulation of G-protein coupled receptor internalization(GO:1904020) negative regulation of G-protein coupled receptor internalization(GO:1904021) |
| 4.1 | 36.6 | GO:1901552 | positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142) |
| 4.0 | 16.0 | GO:0019086 | late viral transcription(GO:0019086) |
| 4.0 | 19.8 | GO:2001181 | positive regulation of interleukin-10 secretion(GO:2001181) |
| 3.9 | 15.8 | GO:2001034 | histone H3-K36 dimethylation(GO:0097676) positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034) |
| 3.9 | 7.8 | GO:0021966 | corticospinal neuron axon guidance(GO:0021966) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623) |
| 3.9 | 19.6 | GO:1902093 | positive regulation of sperm motility(GO:1902093) |
| 3.9 | 11.7 | GO:1903526 | negative regulation of membrane tubulation(GO:1903526) |
| 3.9 | 27.2 | GO:1901509 | regulation of endothelial tube morphogenesis(GO:1901509) |
| 3.9 | 58.1 | GO:0021694 | cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) |
| 3.9 | 11.6 | GO:1902490 | regulation of sperm capacitation(GO:1902490) |
| 3.9 | 3.9 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
| 3.9 | 27.0 | GO:1900112 | regulation of histone H3-K9 trimethylation(GO:1900112) |
| 3.8 | 11.5 | GO:0030186 | melatonin metabolic process(GO:0030186) melatonin biosynthetic process(GO:0030187) |
| 3.8 | 11.4 | GO:1901052 | sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053) |
| 3.8 | 18.9 | GO:0030070 | insulin processing(GO:0030070) |
| 3.8 | 60.2 | GO:0098712 | L-glutamate import across plasma membrane(GO:0098712) |
| 3.8 | 11.3 | GO:0061536 | glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537) |
| 3.7 | 29.8 | GO:0071907 | determination of digestive tract left/right asymmetry(GO:0071907) |
| 3.7 | 7.5 | GO:0070256 | negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) negative regulation of mucus secretion(GO:0070256) |
| 3.7 | 11.2 | GO:0048319 | axial mesoderm morphogenesis(GO:0048319) |
| 3.6 | 7.3 | GO:0070213 | protein auto-ADP-ribosylation(GO:0070213) |
| 3.6 | 7.3 | GO:0097017 | renal protein absorption(GO:0097017) |
| 3.6 | 14.4 | GO:0007089 | traversing start control point of mitotic cell cycle(GO:0007089) |
| 3.6 | 17.8 | GO:0032632 | interleukin-3 production(GO:0032632) |
| 3.6 | 24.9 | GO:1990822 | basic amino acid transmembrane transport(GO:1990822) |
| 3.5 | 10.6 | GO:0061184 | dermatome development(GO:0061054) regulation of dermatome development(GO:0061183) positive regulation of dermatome development(GO:0061184) |
| 3.5 | 52.6 | GO:0035878 | nail development(GO:0035878) |
| 3.5 | 10.5 | GO:0014813 | skeletal muscle satellite cell commitment(GO:0014813) |
| 3.5 | 28.0 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
| 3.5 | 3.5 | GO:0086068 | Purkinje myocyte to ventricular cardiac muscle cell signaling(GO:0086029) Purkinje myocyte to ventricular cardiac muscle cell communication(GO:0086068) |
| 3.5 | 10.4 | GO:0099515 | actin filament-based transport(GO:0099515) |
| 3.5 | 20.8 | GO:0002225 | positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803) |
| 3.4 | 3.4 | GO:0046668 | regulation of retinal cell programmed cell death(GO:0046668) |
| 3.4 | 10.2 | GO:0043504 | mitochondrial DNA repair(GO:0043504) |
| 3.4 | 13.6 | GO:0072660 | maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
| 3.4 | 10.2 | GO:0008614 | pyridoxine metabolic process(GO:0008614) pyridoxine biosynthetic process(GO:0008615) vitamin B6 biosynthetic process(GO:0042819) |
| 3.4 | 33.8 | GO:0021633 | optic nerve structural organization(GO:0021633) |
| 3.4 | 10.1 | GO:0003245 | cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245) positive regulation of chromatin silencing(GO:0031937) |
| 3.3 | 3.3 | GO:0043932 | ossification involved in bone remodeling(GO:0043932) |
| 3.3 | 13.3 | GO:0010836 | negative regulation of protein ADP-ribosylation(GO:0010836) |
| 3.3 | 10.0 | GO:0044805 | late nucleophagy(GO:0044805) |
| 3.3 | 9.9 | GO:0018094 | protein polyglycylation(GO:0018094) |
| 3.3 | 3.3 | GO:0071280 | cellular response to copper ion(GO:0071280) |
| 3.3 | 55.3 | GO:0090361 | platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361) |
| 3.3 | 39.0 | GO:0086046 | membrane depolarization during SA node cell action potential(GO:0086046) |
| 3.2 | 22.7 | GO:2000324 | positive regulation of glucocorticoid receptor signaling pathway(GO:2000324) |
| 3.2 | 22.6 | GO:1902075 | cellular response to salt(GO:1902075) |
| 3.2 | 12.8 | GO:0002881 | negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881) |
| 3.2 | 9.6 | GO:1901842 | negative regulation of high voltage-gated calcium channel activity(GO:1901842) |
| 3.2 | 6.4 | GO:0032304 | negative regulation of icosanoid secretion(GO:0032304) |
| 3.2 | 6.4 | GO:1903348 | positive regulation of bicellular tight junction assembly(GO:1903348) |
| 3.2 | 12.7 | GO:0097167 | circadian regulation of translation(GO:0097167) |
| 3.1 | 25.0 | GO:0006777 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) |
| 3.1 | 9.3 | GO:0021965 | spinal cord ventral commissure morphogenesis(GO:0021965) |
| 3.1 | 15.5 | GO:0001955 | blood vessel maturation(GO:0001955) |
| 3.1 | 12.4 | GO:0080154 | regulation of fertilization(GO:0080154) |
| 3.1 | 15.4 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
| 3.0 | 6.1 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
| 3.0 | 51.5 | GO:0007196 | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196) |
| 3.0 | 9.0 | GO:0038193 | thromboxane A2 signaling pathway(GO:0038193) |
| 3.0 | 9.0 | GO:1901895 | negative regulation of calcium-transporting ATPase activity(GO:1901895) |
| 3.0 | 39.2 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 3.0 | 27.0 | GO:0060267 | positive regulation of respiratory burst(GO:0060267) |
| 3.0 | 9.0 | GO:0051295 | establishment of meiotic spindle localization(GO:0051295) |
| 3.0 | 8.9 | GO:1905071 | occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075) |
| 3.0 | 26.7 | GO:0048642 | negative regulation of skeletal muscle tissue development(GO:0048642) |
| 2.9 | 17.5 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
| 2.9 | 26.0 | GO:0050882 | voluntary musculoskeletal movement(GO:0050882) |
| 2.9 | 31.6 | GO:0042373 | vitamin K metabolic process(GO:0042373) |
| 2.9 | 14.3 | GO:0043415 | positive regulation of skeletal muscle tissue regeneration(GO:0043415) regulation of skeletal muscle tissue regeneration(GO:0043416) |
| 2.9 | 25.7 | GO:0060136 | embryonic process involved in female pregnancy(GO:0060136) |
| 2.8 | 19.9 | GO:0045602 | negative regulation of endothelial cell differentiation(GO:0045602) |
| 2.8 | 28.4 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
| 2.8 | 31.1 | GO:0097186 | amelogenesis(GO:0097186) |
| 2.8 | 5.6 | GO:0021999 | neural plate anterior/posterior regionalization(GO:0021999) |
| 2.8 | 8.3 | GO:0050653 | chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653) |
| 2.7 | 13.6 | GO:0032286 | central nervous system myelin maintenance(GO:0032286) |
| 2.7 | 16.3 | GO:0036018 | cellular response to erythropoietin(GO:0036018) |
| 2.7 | 16.3 | GO:0070212 | protein poly-ADP-ribosylation(GO:0070212) |
| 2.7 | 10.8 | GO:0030035 | microspike assembly(GO:0030035) |
| 2.7 | 16.1 | GO:0007000 | nucleolus organization(GO:0007000) |
| 2.7 | 8.0 | GO:0010133 | proline catabolic process to glutamate(GO:0010133) |
| 2.7 | 10.7 | GO:0071409 | cellular response to cycloheximide(GO:0071409) |
| 2.7 | 13.4 | GO:0070370 | heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370) |
| 2.6 | 5.3 | GO:0007525 | somatic muscle development(GO:0007525) |
| 2.6 | 29.0 | GO:0038003 | opioid receptor signaling pathway(GO:0038003) |
| 2.6 | 7.9 | GO:0016476 | regulation of embryonic cell shape(GO:0016476) glomerular visceral epithelial cell migration(GO:0090521) |
| 2.6 | 5.3 | GO:1900186 | negative regulation of clathrin-mediated endocytosis(GO:1900186) |
| 2.6 | 44.5 | GO:0001829 | trophectodermal cell differentiation(GO:0001829) |
| 2.6 | 7.8 | GO:0071486 | response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473) retinal cell apoptotic process(GO:1990009) |
| 2.6 | 13.0 | GO:0045925 | positive regulation of female receptivity(GO:0045925) |
| 2.6 | 23.2 | GO:1901223 | negative regulation of NIK/NF-kappaB signaling(GO:1901223) |
| 2.6 | 12.8 | GO:0010700 | negative regulation of norepinephrine secretion(GO:0010700) |
| 2.6 | 38.3 | GO:1904714 | regulation of chaperone-mediated autophagy(GO:1904714) |
| 2.5 | 33.1 | GO:0030050 | vesicle transport along actin filament(GO:0030050) |
| 2.5 | 12.7 | GO:1900245 | positive regulation of MDA-5 signaling pathway(GO:1900245) |
| 2.5 | 12.7 | GO:0030259 | lipid glycosylation(GO:0030259) |
| 2.5 | 25.3 | GO:1903358 | regulation of Golgi organization(GO:1903358) |
| 2.5 | 30.3 | GO:0070327 | thyroid hormone transport(GO:0070327) |
| 2.5 | 7.6 | GO:0099557 | trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557) |
| 2.5 | 22.6 | GO:0090091 | positive regulation of extracellular matrix disassembly(GO:0090091) |
| 2.5 | 5.0 | GO:2001168 | regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168) |
| 2.5 | 24.8 | GO:0048711 | positive regulation of astrocyte differentiation(GO:0048711) |
| 2.5 | 7.4 | GO:0001923 | B-1 B cell differentiation(GO:0001923) |
| 2.5 | 19.7 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 2.5 | 68.9 | GO:0014850 | response to muscle activity(GO:0014850) |
| 2.5 | 7.4 | GO:0014859 | negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) |
| 2.5 | 7.4 | GO:2000295 | regulation of hydrogen peroxide catabolic process(GO:2000295) |
| 2.4 | 4.8 | GO:0021558 | trochlear nerve development(GO:0021558) |
| 2.4 | 9.5 | GO:0002215 | defense response to nematode(GO:0002215) |
| 2.4 | 7.1 | GO:0042560 | folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560) |
| 2.4 | 11.9 | GO:0032899 | regulation of neurotrophin production(GO:0032899) |
| 2.4 | 23.6 | GO:0070445 | oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445) |
| 2.4 | 7.1 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
| 2.4 | 9.4 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
| 2.4 | 7.1 | GO:0071529 | cementum mineralization(GO:0071529) |
| 2.3 | 9.4 | GO:0015793 | glycerol transport(GO:0015793) |
| 2.3 | 21.1 | GO:0042487 | regulation of odontogenesis of dentin-containing tooth(GO:0042487) |
| 2.3 | 35.1 | GO:0030205 | dermatan sulfate metabolic process(GO:0030205) |
| 2.3 | 7.0 | GO:1902951 | negative regulation of dendritic spine maintenance(GO:1902951) |
| 2.3 | 11.6 | GO:0045872 | positive regulation of rhodopsin gene expression(GO:0045872) |
| 2.3 | 69.8 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 2.3 | 9.3 | GO:0072014 | proximal tubule development(GO:0072014) |
| 2.3 | 157.4 | GO:0006501 | C-terminal protein lipidation(GO:0006501) |
| 2.3 | 92.6 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 2.3 | 11.6 | GO:1902613 | regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262) |
| 2.3 | 13.9 | GO:0032489 | regulation of Cdc42 protein signal transduction(GO:0032489) |
| 2.3 | 4.6 | GO:0060054 | positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054) |
| 2.2 | 4.5 | GO:0098735 | positive regulation of the force of heart contraction(GO:0098735) |
| 2.2 | 13.4 | GO:0014067 | negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067) |
| 2.2 | 11.2 | GO:0046167 | glycerol-3-phosphate biosynthetic process(GO:0046167) |
| 2.2 | 26.6 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
| 2.2 | 17.6 | GO:0003406 | retinal pigment epithelium development(GO:0003406) |
| 2.2 | 4.4 | GO:1905154 | negative regulation of membrane invagination(GO:1905154) |
| 2.2 | 13.2 | GO:0060158 | phospholipase C-activating dopamine receptor signaling pathway(GO:0060158) |
| 2.2 | 10.9 | GO:0038170 | somatostatin receptor signaling pathway(GO:0038169) somatostatin signaling pathway(GO:0038170) |
| 2.2 | 10.9 | GO:2000834 | androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836) |
| 2.2 | 65.2 | GO:0097503 | sialylation(GO:0097503) |
| 2.2 | 73.8 | GO:0014072 | response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278) |
| 2.2 | 17.3 | GO:0070995 | NADPH oxidation(GO:0070995) |
| 2.2 | 308.9 | GO:0006958 | complement activation, classical pathway(GO:0006958) |
| 2.2 | 8.6 | GO:1903631 | regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634) |
| 2.1 | 12.9 | GO:0016560 | protein import into peroxisome matrix, docking(GO:0016560) |
| 2.1 | 6.4 | GO:0032782 | bile acid secretion(GO:0032782) |
| 2.1 | 10.5 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
| 2.1 | 10.4 | GO:2000672 | negative regulation of motor neuron apoptotic process(GO:2000672) |
| 2.1 | 12.4 | GO:0006543 | glutamine catabolic process(GO:0006543) |
| 2.1 | 4.1 | GO:2000671 | regulation of motor neuron apoptotic process(GO:2000671) |
| 2.1 | 6.2 | GO:1990086 | lens fiber cell apoptotic process(GO:1990086) |
| 2.1 | 4.1 | GO:0046016 | carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436) carbon catabolite activation of transcription(GO:0045991) positive regulation of transcription by glucose(GO:0046016) |
| 2.1 | 6.2 | GO:0019075 | virus maturation(GO:0019075) |
| 2.0 | 2.0 | GO:0048242 | regulation of epinephrine secretion(GO:0014060) epinephrine secretion(GO:0048242) |
| 2.0 | 6.1 | GO:1904479 | negative regulation of intestinal absorption(GO:1904479) |
| 2.0 | 12.2 | GO:1901029 | negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029) |
| 2.0 | 10.1 | GO:0071896 | protein localization to adherens junction(GO:0071896) |
| 2.0 | 26.2 | GO:1900364 | single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) negative regulation of mRNA polyadenylation(GO:1900364) |
| 2.0 | 10.0 | GO:2000382 | positive regulation of mesoderm development(GO:2000382) |
| 2.0 | 6.0 | GO:0045110 | intermediate filament bundle assembly(GO:0045110) |
| 2.0 | 6.0 | GO:0002416 | IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416) |
| 2.0 | 4.0 | GO:0060369 | positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) |
| 2.0 | 11.9 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
| 2.0 | 5.9 | GO:0048318 | axial mesoderm development(GO:0048318) |
| 1.9 | 7.8 | GO:0018894 | dibenzo-p-dioxin metabolic process(GO:0018894) |
| 1.9 | 52.5 | GO:0071420 | cellular response to histamine(GO:0071420) |
| 1.9 | 19.2 | GO:0033123 | positive regulation of purine nucleotide catabolic process(GO:0033123) |
| 1.9 | 5.7 | GO:0003011 | diaphragm contraction(GO:0002086) involuntary skeletal muscle contraction(GO:0003011) |
| 1.9 | 9.6 | GO:2001271 | negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271) |
| 1.9 | 11.4 | GO:0006489 | dolichyl diphosphate biosynthetic process(GO:0006489) dolichyl diphosphate metabolic process(GO:0046465) |
| 1.9 | 13.3 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
| 1.9 | 5.7 | GO:0061073 | ciliary body morphogenesis(GO:0061073) |
| 1.9 | 11.4 | GO:0033133 | positive regulation of glucokinase activity(GO:0033133) |
| 1.9 | 11.2 | GO:0018343 | protein farnesylation(GO:0018343) |
| 1.9 | 14.9 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 1.8 | 7.4 | GO:0014807 | regulation of somitogenesis(GO:0014807) |
| 1.8 | 5.5 | GO:0090403 | oxidative stress-induced premature senescence(GO:0090403) |
| 1.8 | 9.1 | GO:0051901 | positive regulation of mitochondrial depolarization(GO:0051901) positive regulation of membrane depolarization(GO:1904181) |
| 1.8 | 10.8 | GO:0046092 | deoxycytidine metabolic process(GO:0046092) |
| 1.8 | 5.3 | GO:0042412 | taurine biosynthetic process(GO:0042412) |
| 1.8 | 14.2 | GO:0006477 | protein sulfation(GO:0006477) |
| 1.8 | 35.2 | GO:0048490 | anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517) |
| 1.8 | 10.5 | GO:0051902 | negative regulation of mitochondrial depolarization(GO:0051902) |
| 1.8 | 8.8 | GO:2000467 | positive regulation of glycogen (starch) synthase activity(GO:2000467) |
| 1.7 | 10.5 | GO:0032383 | regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383) |
| 1.7 | 34.6 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 1.7 | 31.1 | GO:0097091 | synaptic vesicle clustering(GO:0097091) |
| 1.7 | 15.5 | GO:0032119 | sequestering of zinc ion(GO:0032119) |
| 1.7 | 15.4 | GO:0009223 | pyrimidine deoxyribonucleotide catabolic process(GO:0009223) |
| 1.7 | 5.1 | GO:1990637 | response to prolactin(GO:1990637) |
| 1.7 | 15.3 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 1.7 | 13.6 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
| 1.7 | 8.5 | GO:0051029 | rRNA transport(GO:0051029) |
| 1.7 | 10.2 | GO:1990573 | potassium ion import across plasma membrane(GO:1990573) |
| 1.7 | 15.3 | GO:0006857 | oligopeptide transport(GO:0006857) |
| 1.7 | 18.6 | GO:1902018 | negative regulation of cilium assembly(GO:1902018) |
| 1.7 | 6.8 | GO:0007056 | spindle assembly involved in female meiosis(GO:0007056) |
| 1.7 | 5.0 | GO:0001994 | norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994) |
| 1.7 | 49.6 | GO:0071800 | podosome assembly(GO:0071800) |
| 1.7 | 21.5 | GO:0034770 | histone H4-K20 methylation(GO:0034770) |
| 1.6 | 4.9 | GO:0070105 | positive regulation of interleukin-6-mediated signaling pathway(GO:0070105) |
| 1.6 | 16.2 | GO:2000291 | regulation of myoblast proliferation(GO:2000291) |
| 1.6 | 6.5 | GO:0060282 | positive regulation of oocyte development(GO:0060282) |
| 1.6 | 4.8 | GO:0061428 | negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
| 1.6 | 3.2 | GO:0032881 | regulation of polysaccharide metabolic process(GO:0032881) regulation of glycogen metabolic process(GO:0070873) |
| 1.6 | 1.6 | GO:1904017 | cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 1.6 | 55.8 | GO:0072378 | blood coagulation, fibrin clot formation(GO:0072378) |
| 1.6 | 8.0 | GO:0006574 | valine catabolic process(GO:0006574) |
| 1.6 | 9.5 | GO:0061205 | alveolar primary septum development(GO:0061143) paramesonephric duct development(GO:0061205) |
| 1.6 | 7.9 | GO:1901569 | leukotriene catabolic process(GO:0036100) leukotriene B4 catabolic process(GO:0036101) leukotriene B4 metabolic process(GO:0036102) icosanoid catabolic process(GO:1901523) fatty acid derivative catabolic process(GO:1901569) |
| 1.6 | 25.3 | GO:0014029 | neural crest formation(GO:0014029) |
| 1.6 | 26.9 | GO:0015812 | gamma-aminobutyric acid transport(GO:0015812) |
| 1.6 | 6.3 | GO:0002644 | negative regulation of tolerance induction(GO:0002644) |
| 1.6 | 11.0 | GO:0048165 | ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731) |
| 1.6 | 3.1 | GO:0060979 | cardiac left ventricle formation(GO:0003218) vasculogenesis involved in coronary vascular morphogenesis(GO:0060979) |
| 1.6 | 17.2 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 1.6 | 10.9 | GO:0010968 | regulation of microtubule nucleation(GO:0010968) |
| 1.5 | 18.6 | GO:0060539 | diaphragm development(GO:0060539) |
| 1.5 | 4.6 | GO:2000661 | positive regulation of interleukin-1-mediated signaling pathway(GO:2000661) |
| 1.5 | 9.2 | GO:1990034 | calcium ion export from cell(GO:1990034) |
| 1.5 | 4.6 | GO:0061107 | seminal vesicle development(GO:0061107) |
| 1.5 | 7.6 | GO:0006546 | glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464) |
| 1.5 | 71.2 | GO:0018149 | peptide cross-linking(GO:0018149) |
| 1.5 | 4.5 | GO:1902525 | regulation of protein monoubiquitination(GO:1902525) |
| 1.5 | 1.5 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 1.5 | 10.5 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
| 1.5 | 6.0 | GO:0090241 | negative regulation of histone H4 acetylation(GO:0090241) |
| 1.5 | 10.5 | GO:0042711 | maternal behavior(GO:0042711) parental behavior(GO:0060746) |
| 1.5 | 1.5 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 1.5 | 92.0 | GO:1902017 | regulation of cilium assembly(GO:1902017) |
| 1.5 | 5.9 | GO:0015910 | peroxisomal long-chain fatty acid import(GO:0015910) |
| 1.5 | 1.5 | GO:0039020 | pronephric nephron tubule development(GO:0039020) |
| 1.4 | 5.8 | GO:0034154 | toll-like receptor 7 signaling pathway(GO:0034154) |
| 1.4 | 5.8 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
| 1.4 | 19.8 | GO:0006751 | glutathione catabolic process(GO:0006751) |
| 1.4 | 5.7 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
| 1.4 | 14.1 | GO:0014059 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
| 1.4 | 7.0 | GO:0010816 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
| 1.4 | 4.2 | GO:0030920 | N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920) |
| 1.4 | 2.8 | GO:0060373 | regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) |
| 1.4 | 15.3 | GO:0036155 | acylglycerol acyl-chain remodeling(GO:0036155) |
| 1.4 | 19.5 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 1.4 | 40.3 | GO:0050919 | negative chemotaxis(GO:0050919) |
| 1.4 | 4.1 | GO:0032571 | response to vitamin K(GO:0032571) |
| 1.4 | 44.8 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 1.4 | 4.1 | GO:0060398 | mineralocorticoid receptor signaling pathway(GO:0031959) regulation of growth hormone receptor signaling pathway(GO:0060398) |
| 1.4 | 8.1 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
| 1.3 | 16.2 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
| 1.3 | 5.4 | GO:2000393 | negative regulation of lamellipodium morphogenesis(GO:2000393) |
| 1.3 | 1.3 | GO:0050849 | negative regulation of calcium-mediated signaling(GO:0050849) |
| 1.3 | 2.7 | GO:1903596 | regulation of gap junction assembly(GO:1903596) |
| 1.3 | 10.6 | GO:0046415 | urate metabolic process(GO:0046415) |
| 1.3 | 4.0 | GO:1900738 | positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738) |
| 1.3 | 4.0 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
| 1.3 | 7.9 | GO:0008291 | acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619) |
| 1.3 | 3.9 | GO:1900042 | positive regulation of interleukin-2 secretion(GO:1900042) |
| 1.3 | 6.5 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
| 1.3 | 14.4 | GO:0001675 | acrosome assembly(GO:0001675) |
| 1.3 | 18.2 | GO:0060732 | positive regulation of inositol phosphate biosynthetic process(GO:0060732) |
| 1.3 | 7.8 | GO:0033152 | immunoglobulin V(D)J recombination(GO:0033152) |
| 1.3 | 9.1 | GO:0034086 | maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088) |
| 1.3 | 3.9 | GO:0042360 | vitamin E metabolic process(GO:0042360) |
| 1.3 | 1.3 | GO:0009624 | response to nematode(GO:0009624) |
| 1.3 | 16.8 | GO:0002726 | positive regulation of T cell cytokine production(GO:0002726) |
| 1.3 | 14.2 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 1.3 | 5.2 | GO:2000158 | positive regulation of ubiquitin-specific protease activity(GO:2000158) |
| 1.3 | 6.4 | GO:0042364 | water-soluble vitamin biosynthetic process(GO:0042364) |
| 1.3 | 3.9 | GO:0090675 | intermicrovillar adhesion(GO:0090675) |
| 1.3 | 6.4 | GO:0002870 | lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911) |
| 1.3 | 5.1 | GO:0031630 | regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630) |
| 1.3 | 7.6 | GO:0022010 | central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291) |
| 1.3 | 3.8 | GO:0042631 | cellular response to water deprivation(GO:0042631) |
| 1.3 | 21.3 | GO:0034389 | lipid particle organization(GO:0034389) |
| 1.2 | 15.0 | GO:0010603 | regulation of cytoplasmic mRNA processing body assembly(GO:0010603) |
| 1.2 | 3.7 | GO:0002503 | peptide antigen assembly with MHC class II protein complex(GO:0002503) |
| 1.2 | 13.7 | GO:0016322 | neuron remodeling(GO:0016322) |
| 1.2 | 4.9 | GO:0016098 | monoterpenoid metabolic process(GO:0016098) |
| 1.2 | 30.8 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 1.2 | 3.7 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 1.2 | 7.4 | GO:0043552 | positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552) |
| 1.2 | 6.1 | GO:0071109 | superior temporal gyrus development(GO:0071109) |
| 1.2 | 49.7 | GO:0070884 | regulation of calcineurin-NFAT signaling cascade(GO:0070884) |
| 1.2 | 13.3 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 1.2 | 4.8 | GO:0098700 | neurotransmitter loading into synaptic vesicle(GO:0098700) |
| 1.2 | 6.0 | GO:1903361 | protein localization to basolateral plasma membrane(GO:1903361) |
| 1.2 | 10.8 | GO:0042428 | serotonin metabolic process(GO:0042428) |
| 1.2 | 8.4 | GO:0036152 | phosphatidylethanolamine acyl-chain remodeling(GO:0036152) |
| 1.2 | 1.2 | GO:1900094 | nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry(GO:1900094) nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900164) |
| 1.2 | 4.7 | GO:0018101 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
| 1.2 | 5.9 | GO:0002778 | antimicrobial peptide production(GO:0002775) antibacterial peptide production(GO:0002778) |
| 1.2 | 92.1 | GO:1903779 | regulation of cardiac conduction(GO:1903779) |
| 1.2 | 18.6 | GO:0003254 | regulation of membrane depolarization(GO:0003254) |
| 1.2 | 7.0 | GO:0001554 | luteolysis(GO:0001554) |
| 1.2 | 9.3 | GO:0010623 | programmed cell death involved in cell development(GO:0010623) |
| 1.2 | 52.2 | GO:0003009 | skeletal muscle contraction(GO:0003009) |
| 1.2 | 2.3 | GO:1900005 | positive regulation of serine-type endopeptidase activity(GO:1900005) positive regulation of serine-type peptidase activity(GO:1902573) |
| 1.2 | 4.6 | GO:0038161 | prolactin signaling pathway(GO:0038161) |
| 1.2 | 13.9 | GO:0014010 | Schwann cell proliferation(GO:0014010) |
| 1.2 | 20.7 | GO:0071872 | response to epinephrine(GO:0071871) cellular response to epinephrine stimulus(GO:0071872) |
| 1.2 | 15.0 | GO:0006705 | mineralocorticoid biosynthetic process(GO:0006705) mineralocorticoid metabolic process(GO:0008212) |
| 1.1 | 19.5 | GO:0007130 | synaptonemal complex assembly(GO:0007130) |
| 1.1 | 5.7 | GO:0046208 | spermine catabolic process(GO:0046208) |
| 1.1 | 9.2 | GO:0051005 | negative regulation of lipoprotein lipase activity(GO:0051005) |
| 1.1 | 16.0 | GO:0019852 | L-ascorbic acid metabolic process(GO:0019852) |
| 1.1 | 34.2 | GO:0006706 | steroid catabolic process(GO:0006706) |
| 1.1 | 10.3 | GO:0042148 | strand invasion(GO:0042148) |
| 1.1 | 21.6 | GO:0021513 | spinal cord dorsal/ventral patterning(GO:0021513) |
| 1.1 | 2.3 | GO:0006258 | UDP-glucose catabolic process(GO:0006258) |
| 1.1 | 21.5 | GO:0035435 | phosphate ion transmembrane transport(GO:0035435) |
| 1.1 | 3.4 | GO:0034499 | late endosome to Golgi transport(GO:0034499) |
| 1.1 | 45.8 | GO:0048168 | regulation of neuronal synaptic plasticity(GO:0048168) |
| 1.1 | 22.3 | GO:0006068 | ethanol catabolic process(GO:0006068) |
| 1.1 | 10.0 | GO:0001542 | ovulation from ovarian follicle(GO:0001542) |
| 1.1 | 15.5 | GO:0045109 | intermediate filament organization(GO:0045109) |
| 1.1 | 4.4 | GO:1901300 | positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) |
| 1.1 | 9.9 | GO:0007512 | adult heart development(GO:0007512) |
| 1.1 | 20.7 | GO:0097150 | neuronal stem cell population maintenance(GO:0097150) |
| 1.1 | 10.8 | GO:1902669 | positive regulation of axon guidance(GO:1902669) |
| 1.1 | 4.3 | GO:0019418 | sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221) |
| 1.1 | 17.1 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 1.1 | 6.4 | GO:0072592 | oxygen metabolic process(GO:0072592) |
| 1.1 | 6.4 | GO:0090527 | actin filament reorganization(GO:0090527) |
| 1.1 | 18.0 | GO:0002026 | regulation of the force of heart contraction(GO:0002026) |
| 1.0 | 13.6 | GO:0070571 | negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571) |
| 1.0 | 3.1 | GO:0034058 | endosomal vesicle fusion(GO:0034058) |
| 1.0 | 7.3 | GO:0060481 | lobar bronchus epithelium development(GO:0060481) |
| 1.0 | 2.1 | GO:0034729 | histone H3-K79 methylation(GO:0034729) |
| 1.0 | 6.2 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 1.0 | 28.8 | GO:0021772 | olfactory bulb development(GO:0021772) |
| 1.0 | 9.2 | GO:0045721 | negative regulation of gluconeogenesis(GO:0045721) |
| 1.0 | 6.1 | GO:0002024 | diet induced thermogenesis(GO:0002024) |
| 1.0 | 5.1 | GO:0016075 | rRNA catabolic process(GO:0016075) |
| 1.0 | 22.0 | GO:0098743 | cell aggregation(GO:0098743) |
| 1.0 | 43.9 | GO:0050853 | B cell receptor signaling pathway(GO:0050853) |
| 1.0 | 6.9 | GO:0042670 | retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) |
| 1.0 | 12.8 | GO:0006600 | creatine metabolic process(GO:0006600) |
| 1.0 | 5.9 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 1.0 | 4.9 | GO:0032957 | inositol trisphosphate metabolic process(GO:0032957) |
| 1.0 | 4.8 | GO:0097460 | ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
| 1.0 | 7.8 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
| 1.0 | 45.5 | GO:0051646 | mitochondrion localization(GO:0051646) |
| 1.0 | 30.8 | GO:0099601 | regulation of neurotransmitter receptor activity(GO:0099601) |
| 1.0 | 2.9 | GO:1902430 | negative regulation of beta-amyloid formation(GO:1902430) |
| 1.0 | 95.5 | GO:0050911 | detection of chemical stimulus involved in sensory perception of smell(GO:0050911) |
| 0.9 | 3.8 | GO:0009950 | dorsal/ventral axis specification(GO:0009950) |
| 0.9 | 16.0 | GO:0090051 | negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) |
| 0.9 | 11.2 | GO:0034356 | NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356) |
| 0.9 | 3.7 | GO:0090037 | positive regulation of protein kinase C signaling(GO:0090037) |
| 0.9 | 14.9 | GO:0033169 | histone H3-K9 demethylation(GO:0033169) |
| 0.9 | 18.6 | GO:0045687 | positive regulation of glial cell differentiation(GO:0045687) |
| 0.9 | 7.4 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.9 | 6.4 | GO:0045780 | positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852) |
| 0.9 | 5.5 | GO:0072676 | lymphocyte migration(GO:0072676) |
| 0.9 | 14.6 | GO:0042135 | neurotransmitter catabolic process(GO:0042135) |
| 0.9 | 2.7 | GO:0070272 | proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272) |
| 0.9 | 7.2 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.9 | 14.5 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.9 | 4.5 | GO:0071027 | RNA surveillance(GO:0071025) nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028) |
| 0.9 | 8.0 | GO:0002438 | acute inflammatory response to antigenic stimulus(GO:0002438) |
| 0.9 | 15.1 | GO:0036149 | phosphatidylinositol acyl-chain remodeling(GO:0036149) |
| 0.9 | 11.3 | GO:2000623 | regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623) |
| 0.9 | 2.6 | GO:0032971 | regulation of muscle filament sliding(GO:0032971) |
| 0.9 | 4.3 | GO:0045725 | positive regulation of glycogen biosynthetic process(GO:0045725) |
| 0.9 | 1.7 | GO:0021940 | positive regulation of cerebellar granule cell precursor proliferation(GO:0021940) |
| 0.9 | 0.9 | GO:1902630 | regulation of membrane hyperpolarization(GO:1902630) |
| 0.9 | 5.1 | GO:2000811 | negative regulation of anoikis(GO:2000811) |
| 0.8 | 8.5 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.8 | 22.7 | GO:0007214 | gamma-aminobutyric acid signaling pathway(GO:0007214) |
| 0.8 | 8.3 | GO:0015871 | choline transport(GO:0015871) |
| 0.8 | 3.3 | GO:0097029 | mature conventional dendritic cell differentiation(GO:0097029) |
| 0.8 | 10.8 | GO:0045956 | positive regulation of calcium ion-dependent exocytosis(GO:0045956) |
| 0.8 | 41.8 | GO:0034260 | negative regulation of GTPase activity(GO:0034260) |
| 0.8 | 14.6 | GO:1903861 | regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861) |
| 0.8 | 16.2 | GO:2000114 | regulation of establishment of cell polarity(GO:2000114) |
| 0.8 | 4.0 | GO:0061762 | CAMKK-AMPK signaling cascade(GO:0061762) |
| 0.8 | 5.6 | GO:0042797 | 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797) |
| 0.8 | 6.2 | GO:0033173 | calcineurin-NFAT signaling cascade(GO:0033173) |
| 0.8 | 7.0 | GO:0033005 | positive regulation of mast cell activation(GO:0033005) |
| 0.8 | 4.6 | GO:0050691 | regulation of defense response to virus by host(GO:0050691) |
| 0.8 | 70.9 | GO:0007041 | lysosomal transport(GO:0007041) |
| 0.8 | 2.3 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) |
| 0.8 | 12.9 | GO:0006152 | purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130) |
| 0.8 | 1.5 | GO:0000965 | mitochondrial RNA 3'-end processing(GO:0000965) |
| 0.8 | 4.5 | GO:1902510 | regulation of apoptotic DNA fragmentation(GO:1902510) |
| 0.7 | 1.5 | GO:0015670 | carbon dioxide transport(GO:0015670) |
| 0.7 | 5.2 | GO:0051974 | negative regulation of telomerase activity(GO:0051974) |
| 0.7 | 3.7 | GO:1903975 | regulation of glial cell migration(GO:1903975) |
| 0.7 | 6.6 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 0.7 | 13.1 | GO:0010719 | negative regulation of epithelial to mesenchymal transition(GO:0010719) |
| 0.7 | 6.6 | GO:0032516 | positive regulation of phosphoprotein phosphatase activity(GO:0032516) |
| 0.7 | 14.5 | GO:1904778 | regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778) |
| 0.7 | 6.5 | GO:0010172 | embryonic body morphogenesis(GO:0010172) |
| 0.7 | 15.0 | GO:0060291 | long-term synaptic potentiation(GO:0060291) |
| 0.7 | 11.4 | GO:0072539 | T-helper 17 cell differentiation(GO:0072539) |
| 0.7 | 7.8 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.7 | 5.0 | GO:0006975 | DNA damage induced protein phosphorylation(GO:0006975) |
| 0.7 | 2.8 | GO:0034343 | type III interferon production(GO:0034343) regulation of type III interferon production(GO:0034344) |
| 0.7 | 7.0 | GO:0010644 | cell communication by electrical coupling(GO:0010644) |
| 0.7 | 18.3 | GO:0050912 | detection of chemical stimulus involved in sensory perception of taste(GO:0050912) |
| 0.7 | 21.8 | GO:0070328 | acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328) |
| 0.7 | 7.0 | GO:0030813 | positive regulation of nucleotide catabolic process(GO:0030813) positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197) |
| 0.7 | 6.3 | GO:0043320 | natural killer cell degranulation(GO:0043320) |
| 0.7 | 6.9 | GO:0043922 | negative regulation by host of viral transcription(GO:0043922) |
| 0.7 | 6.9 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.7 | 6.9 | GO:0002230 | positive regulation of defense response to virus by host(GO:0002230) |
| 0.7 | 2.8 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
| 0.7 | 11.0 | GO:0006670 | sphingosine metabolic process(GO:0006670) diol metabolic process(GO:0034311) |
| 0.7 | 28.9 | GO:0048247 | lymphocyte chemotaxis(GO:0048247) |
| 0.7 | 26.6 | GO:0033572 | transferrin transport(GO:0033572) |
| 0.7 | 5.5 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
| 0.7 | 16.2 | GO:0019731 | antibacterial humoral response(GO:0019731) |
| 0.7 | 19.6 | GO:0035082 | axoneme assembly(GO:0035082) |
| 0.7 | 6.7 | GO:0032026 | response to magnesium ion(GO:0032026) |
| 0.7 | 0.7 | GO:0043366 | beta selection(GO:0043366) |
| 0.7 | 16.8 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
| 0.7 | 17.4 | GO:0015695 | organic cation transport(GO:0015695) |
| 0.7 | 2.0 | GO:0038030 | non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
| 0.7 | 7.4 | GO:0015074 | DNA integration(GO:0015074) |
| 0.7 | 3.3 | GO:0060440 | trachea formation(GO:0060440) |
| 0.7 | 2.0 | GO:0072092 | ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093) |
| 0.7 | 9.9 | GO:0006833 | water transport(GO:0006833) |
| 0.7 | 3.9 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 0.7 | 33.3 | GO:0045652 | regulation of megakaryocyte differentiation(GO:0045652) |
| 0.6 | 5.8 | GO:0002115 | store-operated calcium entry(GO:0002115) |
| 0.6 | 3.9 | GO:1901626 | regulation of postsynaptic membrane organization(GO:1901626) |
| 0.6 | 2.6 | GO:0097089 | methyl-branched fatty acid metabolic process(GO:0097089) |
| 0.6 | 4.5 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.6 | 5.2 | GO:0035457 | cellular response to interferon-alpha(GO:0035457) |
| 0.6 | 14.2 | GO:0034204 | lipid translocation(GO:0034204) phospholipid translocation(GO:0045332) |
| 0.6 | 6.4 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
| 0.6 | 12.2 | GO:0010107 | potassium ion import(GO:0010107) |
| 0.6 | 7.0 | GO:0090042 | tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043) |
| 0.6 | 5.7 | GO:0046641 | positive regulation of alpha-beta T cell proliferation(GO:0046641) |
| 0.6 | 5.0 | GO:0020027 | hemoglobin metabolic process(GO:0020027) |
| 0.6 | 5.6 | GO:0051127 | positive regulation of actin nucleation(GO:0051127) |
| 0.6 | 1.9 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
| 0.6 | 8.6 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 0.6 | 2.5 | GO:0015811 | L-cystine transport(GO:0015811) |
| 0.6 | 5.4 | GO:0031282 | regulation of guanylate cyclase activity(GO:0031282) positive regulation of guanylate cyclase activity(GO:0031284) |
| 0.6 | 26.8 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.6 | 4.8 | GO:2000096 | positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096) |
| 0.6 | 14.9 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
| 0.6 | 7.7 | GO:0009250 | glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250) |
| 0.6 | 6.5 | GO:0006552 | leucine catabolic process(GO:0006552) |
| 0.6 | 2.4 | GO:0090315 | negative regulation of protein targeting to membrane(GO:0090315) |
| 0.6 | 4.1 | GO:0051152 | positive regulation of smooth muscle cell differentiation(GO:0051152) |
| 0.6 | 5.9 | GO:0002455 | humoral immune response mediated by circulating immunoglobulin(GO:0002455) |
| 0.6 | 8.2 | GO:0006111 | regulation of gluconeogenesis(GO:0006111) |
| 0.6 | 17.0 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.6 | 8.0 | GO:0016576 | histone dephosphorylation(GO:0016576) |
| 0.6 | 9.7 | GO:0019371 | cyclooxygenase pathway(GO:0019371) |
| 0.6 | 3.4 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.6 | 14.8 | GO:0046473 | phosphatidic acid metabolic process(GO:0046473) |
| 0.6 | 35.9 | GO:0090630 | activation of GTPase activity(GO:0090630) |
| 0.6 | 2.8 | GO:0060370 | susceptibility to T cell mediated cytotoxicity(GO:0060370) |
| 0.6 | 4.5 | GO:1902083 | negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) |
| 0.6 | 1.1 | GO:0035994 | response to muscle stretch(GO:0035994) |
| 0.6 | 5.0 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.6 | 1.1 | GO:0090080 | positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080) |
| 0.5 | 2.2 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.5 | 21.2 | GO:1901385 | regulation of voltage-gated calcium channel activity(GO:1901385) |
| 0.5 | 12.5 | GO:0045646 | regulation of erythrocyte differentiation(GO:0045646) |
| 0.5 | 4.7 | GO:0098703 | calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035) |
| 0.5 | 1.0 | GO:0040037 | negative regulation of fibroblast growth factor receptor signaling pathway(GO:0040037) |
| 0.5 | 6.2 | GO:0072017 | distal tubule development(GO:0072017) |
| 0.5 | 5.1 | GO:0048286 | lung alveolus development(GO:0048286) |
| 0.5 | 4.0 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
| 0.5 | 7.0 | GO:0032060 | bleb assembly(GO:0032060) |
| 0.5 | 5.0 | GO:0000447 | endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447) |
| 0.5 | 3.0 | GO:0043217 | peripheral nervous system myelin maintenance(GO:0032287) myelin maintenance(GO:0043217) |
| 0.5 | 4.4 | GO:0046697 | decidualization(GO:0046697) |
| 0.5 | 6.4 | GO:0060662 | tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662) |
| 0.5 | 7.3 | GO:0060612 | adipose tissue development(GO:0060612) |
| 0.5 | 4.3 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
| 0.5 | 6.7 | GO:0035563 | positive regulation of chromatin binding(GO:0035563) |
| 0.5 | 5.7 | GO:0045745 | positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745) |
| 0.5 | 0.5 | GO:0003418 | growth plate cartilage chondrocyte differentiation(GO:0003418) |
| 0.5 | 2.4 | GO:0071352 | cellular response to interleukin-2(GO:0071352) |
| 0.5 | 2.4 | GO:0050962 | detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962) |
| 0.5 | 8.5 | GO:0021854 | hypothalamus development(GO:0021854) |
| 0.5 | 9.9 | GO:0006884 | cell volume homeostasis(GO:0006884) |
| 0.5 | 14.5 | GO:0045026 | plasma membrane fusion(GO:0045026) |
| 0.5 | 12.2 | GO:0035115 | embryonic forelimb morphogenesis(GO:0035115) |
| 0.5 | 28.4 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.5 | 1.9 | GO:2000535 | regulation of entry of bacterium into host cell(GO:2000535) |
| 0.5 | 16.6 | GO:0034067 | protein localization to Golgi apparatus(GO:0034067) |
| 0.5 | 1.4 | GO:0051410 | detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458) |
| 0.5 | 3.6 | GO:0071688 | striated muscle myosin thick filament assembly(GO:0071688) |
| 0.5 | 7.3 | GO:0032515 | negative regulation of phosphoprotein phosphatase activity(GO:0032515) |
| 0.5 | 27.5 | GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502) |
| 0.4 | 22.0 | GO:0042102 | positive regulation of T cell proliferation(GO:0042102) |
| 0.4 | 4.9 | GO:0035855 | megakaryocyte development(GO:0035855) |
| 0.4 | 24.6 | GO:0010923 | negative regulation of phosphatase activity(GO:0010923) |
| 0.4 | 4.0 | GO:0003374 | dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374) |
| 0.4 | 11.0 | GO:0060411 | cardiac septum morphogenesis(GO:0060411) |
| 0.4 | 5.3 | GO:0090026 | positive regulation of monocyte chemotaxis(GO:0090026) |
| 0.4 | 1.8 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
| 0.4 | 6.1 | GO:0000052 | citrulline metabolic process(GO:0000052) |
| 0.4 | 3.1 | GO:1902412 | regulation of mitotic cytokinesis(GO:1902412) |
| 0.4 | 4.4 | GO:0090286 | cytoskeletal anchoring at nuclear membrane(GO:0090286) |
| 0.4 | 15.5 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
| 0.4 | 3.0 | GO:0080009 | mRNA methylation(GO:0080009) |
| 0.4 | 14.6 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 0.4 | 3.8 | GO:0071294 | cellular response to zinc ion(GO:0071294) |
| 0.4 | 8.0 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
| 0.4 | 2.1 | GO:0006788 | heme oxidation(GO:0006788) |
| 0.4 | 8.8 | GO:0030252 | growth hormone secretion(GO:0030252) |
| 0.4 | 11.6 | GO:0045600 | positive regulation of fat cell differentiation(GO:0045600) |
| 0.4 | 14.1 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.4 | 11.1 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.4 | 1.6 | GO:0014827 | intestine smooth muscle contraction(GO:0014827) |
| 0.4 | 8.9 | GO:0035455 | response to interferon-alpha(GO:0035455) |
| 0.4 | 10.1 | GO:0014823 | response to activity(GO:0014823) |
| 0.4 | 3.6 | GO:0008089 | anterograde axonal transport(GO:0008089) |
| 0.4 | 55.6 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
| 0.4 | 3.5 | GO:0001865 | NK T cell differentiation(GO:0001865) |
| 0.4 | 8.4 | GO:0022400 | regulation of rhodopsin mediated signaling pathway(GO:0022400) |
| 0.4 | 5.0 | GO:0071305 | cellular response to vitamin D(GO:0071305) |
| 0.4 | 1.5 | GO:0035860 | glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860) |
| 0.4 | 12.5 | GO:0010863 | positive regulation of phospholipase C activity(GO:0010863) |
| 0.4 | 1.9 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.4 | 7.1 | GO:0001945 | lymph vessel development(GO:0001945) |
| 0.4 | 2.6 | GO:0016081 | synaptic vesicle docking(GO:0016081) |
| 0.4 | 5.8 | GO:0033599 | regulation of mammary gland epithelial cell proliferation(GO:0033599) |
| 0.4 | 6.2 | GO:0045671 | negative regulation of osteoclast differentiation(GO:0045671) |
| 0.4 | 10.9 | GO:0019730 | antimicrobial humoral response(GO:0019730) |
| 0.4 | 4.3 | GO:0060037 | pharyngeal system development(GO:0060037) |
| 0.4 | 6.5 | GO:0003334 | keratinocyte development(GO:0003334) |
| 0.4 | 9.3 | GO:0021675 | nerve development(GO:0021675) |
| 0.4 | 3.2 | GO:0098535 | de novo centriole assembly(GO:0098535) |
| 0.4 | 2.1 | GO:0055059 | asymmetric neuroblast division(GO:0055059) |
| 0.4 | 6.7 | GO:0036092 | phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) |
| 0.4 | 1.1 | GO:0045144 | meiotic sister chromatid segregation(GO:0045144) |
| 0.4 | 2.1 | GO:0070050 | neuron cellular homeostasis(GO:0070050) |
| 0.3 | 0.3 | GO:0010536 | regulation of activation of Janus kinase activity(GO:0010533) positive regulation of activation of Janus kinase activity(GO:0010536) activation of Janus kinase activity(GO:0042976) |
| 0.3 | 8.2 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.3 | 4.1 | GO:0071480 | cellular response to gamma radiation(GO:0071480) |
| 0.3 | 2.0 | GO:0002710 | negative regulation of T cell mediated immunity(GO:0002710) |
| 0.3 | 4.9 | GO:0006692 | prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693) |
| 0.3 | 6.8 | GO:0008535 | respiratory chain complex IV assembly(GO:0008535) |
| 0.3 | 6.8 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 0.3 | 6.0 | GO:0032570 | response to progesterone(GO:0032570) |
| 0.3 | 5.2 | GO:0003322 | pancreatic A cell development(GO:0003322) |
| 0.3 | 1.8 | GO:0031915 | positive regulation of synaptic plasticity(GO:0031915) |
| 0.3 | 3.0 | GO:0034315 | regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315) |
| 0.3 | 3.8 | GO:0090557 | establishment of endothelial intestinal barrier(GO:0090557) |
| 0.3 | 3.8 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.3 | 24.4 | GO:0007286 | spermatid development(GO:0007286) |
| 0.3 | 3.8 | GO:0002323 | natural killer cell activation involved in immune response(GO:0002323) |
| 0.3 | 8.6 | GO:0006400 | tRNA modification(GO:0006400) |
| 0.3 | 3.7 | GO:0045879 | negative regulation of smoothened signaling pathway(GO:0045879) |
| 0.3 | 4.5 | GO:0030317 | sperm motility(GO:0030317) |
| 0.3 | 3.9 | GO:0051131 | chaperone-mediated protein complex assembly(GO:0051131) |
| 0.3 | 2.8 | GO:0050774 | negative regulation of dendrite morphogenesis(GO:0050774) |
| 0.3 | 45.4 | GO:0043401 | steroid hormone mediated signaling pathway(GO:0043401) |
| 0.3 | 9.9 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.3 | 7.0 | GO:1901998 | toxin transport(GO:1901998) |
| 0.3 | 4.5 | GO:0014911 | positive regulation of smooth muscle cell migration(GO:0014911) |
| 0.3 | 1.1 | GO:0033564 | anterior/posterior axon guidance(GO:0033564) |
| 0.3 | 4.2 | GO:0035590 | purinergic nucleotide receptor signaling pathway(GO:0035590) |
| 0.3 | 4.2 | GO:0043550 | regulation of lipid kinase activity(GO:0043550) |
| 0.3 | 3.8 | GO:0060022 | hard palate development(GO:0060022) |
| 0.3 | 7.4 | GO:1904892 | regulation of JAK-STAT cascade(GO:0046425) regulation of STAT cascade(GO:1904892) |
| 0.2 | 1.9 | GO:0051930 | regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931) |
| 0.2 | 2.8 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
| 0.2 | 3.0 | GO:0061756 | leukocyte tethering or rolling(GO:0050901) leukocyte adhesion to vascular endothelial cell(GO:0061756) |
| 0.2 | 8.6 | GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in mitotic G1 DNA damage checkpoint(GO:0072431) intracellular signal transduction involved in G1 DNA damage checkpoint(GO:1902400) |
| 0.2 | 2.1 | GO:0010265 | SCF complex assembly(GO:0010265) |
| 0.2 | 1.1 | GO:0015865 | purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868) |
| 0.2 | 4.1 | GO:0007096 | regulation of exit from mitosis(GO:0007096) |
| 0.2 | 1.6 | GO:0002523 | leukocyte migration involved in inflammatory response(GO:0002523) |
| 0.2 | 2.9 | GO:0007398 | ectoderm development(GO:0007398) |
| 0.2 | 2.2 | GO:0010842 | retina layer formation(GO:0010842) |
| 0.2 | 0.8 | GO:0043569 | negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569) |
| 0.2 | 2.5 | GO:0034472 | snRNA 3'-end processing(GO:0034472) |
| 0.2 | 1.0 | GO:0061744 | motor behavior(GO:0061744) |
| 0.2 | 4.9 | GO:0002040 | sprouting angiogenesis(GO:0002040) |
| 0.2 | 0.4 | GO:0032070 | regulation of deoxyribonuclease activity(GO:0032070) regulation of endodeoxyribonuclease activity(GO:0032071) |
| 0.2 | 1.0 | GO:0032331 | negative regulation of chondrocyte differentiation(GO:0032331) |
| 0.2 | 0.2 | GO:2000417 | negative regulation of eosinophil migration(GO:2000417) |
| 0.2 | 3.5 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.2 | 2.8 | GO:0019433 | triglyceride catabolic process(GO:0019433) |
| 0.2 | 1.1 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.2 | 20.8 | GO:0007601 | visual perception(GO:0007601) |
| 0.2 | 0.5 | GO:0038180 | nerve growth factor signaling pathway(GO:0038180) |
| 0.2 | 2.3 | GO:0018023 | peptidyl-lysine trimethylation(GO:0018023) |
| 0.2 | 5.0 | GO:0006198 | cAMP catabolic process(GO:0006198) |
| 0.2 | 2.9 | GO:0060338 | regulation of type I interferon-mediated signaling pathway(GO:0060338) |
| 0.2 | 4.6 | GO:0021762 | substantia nigra development(GO:0021762) |
| 0.2 | 15.0 | GO:0050796 | regulation of insulin secretion(GO:0050796) |
| 0.2 | 2.4 | GO:0050906 | detection of stimulus involved in sensory perception(GO:0050906) |
| 0.2 | 3.5 | GO:0071539 | protein localization to centrosome(GO:0071539) |
| 0.2 | 1.8 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
| 0.1 | 3.3 | GO:0090200 | positive regulation of release of cytochrome c from mitochondria(GO:0090200) |
| 0.1 | 0.7 | GO:0038042 | dimeric G-protein coupled receptor signaling pathway(GO:0038042) |
| 0.1 | 1.3 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.1 | 4.3 | GO:0048025 | negative regulation of mRNA splicing, via spliceosome(GO:0048025) |
| 0.1 | 1.1 | GO:0050930 | induction of positive chemotaxis(GO:0050930) |
| 0.1 | 0.4 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.1 | 2.2 | GO:0048873 | homeostasis of number of cells within a tissue(GO:0048873) |
| 0.1 | 0.6 | GO:0048596 | embryonic camera-type eye morphogenesis(GO:0048596) |
| 0.1 | 1.0 | GO:0060445 | branching involved in salivary gland morphogenesis(GO:0060445) |
| 0.1 | 2.6 | GO:0070498 | interleukin-1-mediated signaling pathway(GO:0070498) |
| 0.1 | 0.9 | GO:0061302 | smooth muscle cell-matrix adhesion(GO:0061302) |
| 0.1 | 1.8 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 0.1 | 4.4 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
| 0.1 | 58.7 | GO:0043547 | positive regulation of GTPase activity(GO:0043547) |
| 0.1 | 1.1 | GO:1901407 | regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) |
| 0.1 | 0.7 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
| 0.1 | 0.6 | GO:0031666 | positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666) |
| 0.1 | 3.0 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
| 0.1 | 0.2 | GO:0042418 | epinephrine metabolic process(GO:0042414) epinephrine biosynthetic process(GO:0042418) |
| 0.1 | 1.3 | GO:0042354 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.1 | 5.8 | GO:0035113 | embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113) |
| 0.1 | 2.7 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.1 | 0.9 | GO:0071347 | cellular response to interleukin-1(GO:0071347) |
| 0.1 | 1.3 | GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.1 | 1.7 | GO:0010165 | response to X-ray(GO:0010165) |
| 0.1 | 1.0 | GO:0042340 | keratan sulfate catabolic process(GO:0042340) |
| 0.1 | 0.8 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.1 | 1.1 | GO:0006646 | phosphatidylethanolamine biosynthetic process(GO:0006646) |
| 0.1 | 0.1 | GO:0042222 | interleukin-1 biosynthetic process(GO:0042222) interleukin-1 beta biosynthetic process(GO:0050720) |
| 0.1 | 0.9 | GO:0016973 | poly(A)+ mRNA export from nucleus(GO:0016973) |
| 0.0 | 0.1 | GO:1903027 | regulation of opsonization(GO:1903027) |
| 0.0 | 0.4 | GO:0097094 | craniofacial suture morphogenesis(GO:0097094) |
| 0.0 | 1.1 | GO:0019233 | sensory perception of pain(GO:0019233) |
| 0.0 | 0.3 | GO:0006703 | estrogen biosynthetic process(GO:0006703) |
| 0.0 | 0.8 | GO:0035338 | long-chain fatty-acyl-CoA biosynthetic process(GO:0035338) |
| 0.0 | 0.3 | GO:0050829 | defense response to Gram-negative bacterium(GO:0050829) |
| 0.0 | 0.3 | GO:0031280 | negative regulation of adenylate cyclase activity(GO:0007194) negative regulation of cyclase activity(GO:0031280) negative regulation of lyase activity(GO:0051350) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 15.4 | 246.2 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 11.1 | 44.5 | GO:0005602 | complement component C1 complex(GO:0005602) |
| 9.9 | 29.6 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 9.0 | 71.6 | GO:0060199 | clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203) |
| 8.6 | 25.7 | GO:0098831 | cytoskeleton of presynaptic active zone(GO:0048788) presynaptic active zone cytoplasmic component(GO:0098831) presynaptic cytoskeleton(GO:0099569) |
| 8.2 | 24.6 | GO:0071750 | dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752) |
| 7.6 | 68.6 | GO:0098845 | postsynaptic endosome(GO:0098845) |
| 7.5 | 135.5 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
| 7.5 | 22.5 | GO:0031515 | tRNA (m1A) methyltransferase complex(GO:0031515) |
| 6.6 | 39.8 | GO:1990682 | CSF1-CSF1R complex(GO:1990682) |
| 6.6 | 32.9 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 6.4 | 19.2 | GO:0060987 | lipid tube(GO:0060987) |
| 6.2 | 37.3 | GO:0045298 | tubulin complex(GO:0045298) |
| 5.5 | 21.9 | GO:0033596 | TSC1-TSC2 complex(GO:0033596) |
| 5.2 | 26.2 | GO:0032044 | DSIF complex(GO:0032044) |
| 5.2 | 15.6 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
| 5.1 | 10.1 | GO:0097025 | MPP7-DLG1-LIN7 complex(GO:0097025) |
| 4.9 | 83.0 | GO:0033010 | paranodal junction(GO:0033010) |
| 4.4 | 13.3 | GO:0017071 | intracellular cyclic nucleotide activated cation channel complex(GO:0017071) |
| 4.2 | 42.4 | GO:0005614 | interstitial matrix(GO:0005614) |
| 4.1 | 20.3 | GO:0097513 | myosin II filament(GO:0097513) |
| 3.9 | 73.2 | GO:0042613 | MHC class II protein complex(GO:0042613) |
| 3.7 | 26.1 | GO:0072687 | meiotic spindle(GO:0072687) |
| 3.7 | 14.9 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
| 3.6 | 42.8 | GO:0043240 | Fanconi anaemia nuclear complex(GO:0043240) |
| 3.5 | 24.5 | GO:0030893 | meiotic cohesin complex(GO:0030893) |
| 3.5 | 17.3 | GO:1990031 | pinceau fiber(GO:1990031) |
| 3.5 | 17.3 | GO:0031674 | I band(GO:0031674) |
| 3.4 | 10.2 | GO:0031251 | PAN complex(GO:0031251) |
| 3.4 | 10.2 | GO:0005760 | gamma DNA polymerase complex(GO:0005760) |
| 3.4 | 10.1 | GO:0031933 | telomeric heterochromatin(GO:0031933) |
| 3.3 | 39.0 | GO:0097427 | microtubule bundle(GO:0097427) |
| 3.2 | 12.7 | GO:0090533 | cation-transporting ATPase complex(GO:0090533) |
| 3.1 | 22.0 | GO:0071439 | clathrin complex(GO:0071439) |
| 3.1 | 68.3 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 3.0 | 9.1 | GO:0032116 | SMC loading complex(GO:0032116) |
| 2.9 | 17.3 | GO:0001940 | male pronucleus(GO:0001940) |
| 2.9 | 23.1 | GO:0097433 | dense body(GO:0097433) |
| 2.9 | 5.7 | GO:1990584 | cardiac Troponin complex(GO:1990584) |
| 2.8 | 17.0 | GO:0020018 | ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018) |
| 2.8 | 19.8 | GO:0097209 | epidermal lamellar body(GO:0097209) |
| 2.7 | 18.6 | GO:1990635 | proximal dendrite(GO:1990635) |
| 2.6 | 47.5 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 2.6 | 7.8 | GO:0070701 | mucus layer(GO:0070701) |
| 2.6 | 17.9 | GO:0043196 | varicosity(GO:0043196) |
| 2.5 | 12.6 | GO:0044327 | dendritic spine head(GO:0044327) |
| 2.5 | 19.8 | GO:0045179 | apical cortex(GO:0045179) |
| 2.5 | 34.4 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 2.4 | 9.8 | GO:0005826 | actomyosin contractile ring(GO:0005826) |
| 2.4 | 22.0 | GO:0030119 | AP-type membrane coat adaptor complex(GO:0030119) |
| 2.4 | 125.0 | GO:0048786 | presynaptic active zone(GO:0048786) |
| 2.3 | 115.6 | GO:0019814 | immunoglobulin complex(GO:0019814) |
| 2.3 | 20.8 | GO:0071953 | elastic fiber(GO:0071953) |
| 2.3 | 16.0 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
| 2.2 | 11.1 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 2.1 | 31.9 | GO:0005883 | neurofilament(GO:0005883) |
| 2.1 | 16.6 | GO:0000138 | Golgi trans cisterna(GO:0000138) |
| 2.1 | 35.3 | GO:0031045 | dense core granule(GO:0031045) |
| 2.1 | 6.2 | GO:0097443 | sorting endosome(GO:0097443) |
| 2.0 | 13.9 | GO:0034363 | intermediate-density lipoprotein particle(GO:0034363) |
| 2.0 | 94.7 | GO:0001533 | cornified envelope(GO:0001533) |
| 2.0 | 19.6 | GO:0046581 | intercellular canaliculus(GO:0046581) |
| 1.9 | 3.9 | GO:0099634 | postsynaptic specialization membrane(GO:0099634) |
| 1.9 | 25.3 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 1.9 | 9.7 | GO:0000835 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
| 1.9 | 5.8 | GO:0032009 | early phagosome(GO:0032009) |
| 1.9 | 16.9 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 1.9 | 15.0 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 1.8 | 73.6 | GO:1902711 | GABA-A receptor complex(GO:1902711) |
| 1.8 | 7.4 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 1.8 | 28.1 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 1.7 | 8.7 | GO:1990604 | IRE1-TRAF2-ASK1 complex(GO:1990604) |
| 1.7 | 10.4 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 1.7 | 51.9 | GO:0031143 | pseudopodium(GO:0031143) |
| 1.7 | 13.8 | GO:0035976 | AP1 complex(GO:0035976) |
| 1.7 | 12.1 | GO:0036157 | outer dynein arm(GO:0036157) |
| 1.7 | 20.5 | GO:0036057 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 1.7 | 11.9 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 1.7 | 6.8 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
| 1.7 | 6.8 | GO:0038038 | G-protein coupled receptor homodimeric complex(GO:0038038) |
| 1.7 | 23.4 | GO:0043083 | synaptic cleft(GO:0043083) |
| 1.7 | 13.3 | GO:0070187 | telosome(GO:0070187) |
| 1.7 | 16.6 | GO:0098533 | ATPase dependent transmembrane transport complex(GO:0098533) |
| 1.6 | 4.9 | GO:0097224 | sperm connecting piece(GO:0097224) |
| 1.6 | 56.4 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 1.6 | 8.0 | GO:0032444 | activin responsive factor complex(GO:0032444) |
| 1.6 | 12.6 | GO:0097425 | smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425) |
| 1.6 | 36.2 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 1.6 | 11.0 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 1.6 | 7.8 | GO:0005958 | DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) |
| 1.5 | 18.4 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 1.5 | 4.6 | GO:0036030 | protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183) |
| 1.5 | 4.5 | GO:0043293 | apoptosome(GO:0043293) |
| 1.5 | 10.4 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 1.5 | 43.2 | GO:0032589 | neuron projection membrane(GO:0032589) |
| 1.5 | 26.6 | GO:0016471 | vacuolar proton-transporting V-type ATPase complex(GO:0016471) |
| 1.5 | 2.9 | GO:0033268 | node of Ranvier(GO:0033268) |
| 1.5 | 13.2 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 1.5 | 10.2 | GO:1990745 | EARP complex(GO:1990745) |
| 1.4 | 4.3 | GO:0005899 | insulin receptor complex(GO:0005899) |
| 1.4 | 35.8 | GO:0030673 | axolemma(GO:0030673) |
| 1.4 | 49.8 | GO:0071565 | nBAF complex(GO:0071565) |
| 1.4 | 16.9 | GO:0033270 | paranode region of axon(GO:0033270) |
| 1.4 | 18.3 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 1.4 | 13.8 | GO:0042567 | insulin-like growth factor ternary complex(GO:0042567) |
| 1.4 | 12.3 | GO:0044194 | cytolytic granule(GO:0044194) |
| 1.4 | 14.9 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 1.3 | 4.0 | GO:1990316 | ATG1/ULK1 kinase complex(GO:1990316) |
| 1.3 | 5.3 | GO:0070110 | ciliary neurotrophic factor receptor complex(GO:0070110) |
| 1.3 | 23.5 | GO:0032809 | neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298) |
| 1.3 | 205.2 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 1.3 | 15.5 | GO:0097486 | multivesicular body lumen(GO:0097486) |
| 1.3 | 18.0 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 1.3 | 119.5 | GO:0101003 | ficolin-1-rich granule membrane(GO:0101003) |
| 1.3 | 8.9 | GO:0008282 | ATP-sensitive potassium channel complex(GO:0008282) |
| 1.2 | 11.2 | GO:0033391 | chromatoid body(GO:0033391) |
| 1.2 | 23.1 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 1.2 | 3.6 | GO:0005745 | m-AAA complex(GO:0005745) |
| 1.2 | 25.2 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 1.2 | 10.6 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
| 1.2 | 3.5 | GO:0016938 | kinesin I complex(GO:0016938) |
| 1.2 | 26.8 | GO:0001891 | phagocytic cup(GO:0001891) |
| 1.1 | 42.4 | GO:0005859 | muscle myosin complex(GO:0005859) |
| 1.1 | 17.1 | GO:0097440 | apical dendrite(GO:0097440) |
| 1.1 | 13.6 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
| 1.1 | 4.5 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 1.1 | 6.7 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
| 1.1 | 18.1 | GO:0044224 | juxtaparanode region of axon(GO:0044224) |
| 1.1 | 14.9 | GO:0048188 | Set1C/COMPASS complex(GO:0048188) |
| 1.1 | 18.0 | GO:0016461 | unconventional myosin complex(GO:0016461) |
| 1.0 | 28.2 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.9 | 46.0 | GO:0043198 | dendritic shaft(GO:0043198) |
| 0.9 | 8.4 | GO:0042599 | lamellar body(GO:0042599) |
| 0.9 | 1.9 | GO:0005797 | Golgi medial cisterna(GO:0005797) |
| 0.9 | 8.2 | GO:0098554 | cytoplasmic side of endoplasmic reticulum membrane(GO:0098554) |
| 0.9 | 25.5 | GO:0005779 | integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231) |
| 0.9 | 11.4 | GO:0005902 | microvillus(GO:0005902) |
| 0.9 | 9.6 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
| 0.9 | 4.3 | GO:0089701 | U2AF(GO:0089701) |
| 0.9 | 12.8 | GO:0001741 | XY body(GO:0001741) |
| 0.8 | 4.2 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.8 | 2.5 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.8 | 12.4 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.8 | 6.5 | GO:1905202 | 3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202) |
| 0.8 | 23.6 | GO:0000407 | pre-autophagosomal structure(GO:0000407) |
| 0.8 | 130.6 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.8 | 80.1 | GO:0034705 | voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705) |
| 0.8 | 5.6 | GO:0000127 | transcription factor TFIIIC complex(GO:0000127) |
| 0.8 | 13.5 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.8 | 9.5 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.8 | 3.1 | GO:0097123 | cyclin A1-CDK2 complex(GO:0097123) |
| 0.8 | 81.2 | GO:0043204 | perikaryon(GO:0043204) |
| 0.8 | 30.1 | GO:0008305 | integrin complex(GO:0008305) |
| 0.8 | 28.3 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.8 | 11.5 | GO:0005861 | troponin complex(GO:0005861) |
| 0.8 | 6.1 | GO:0031258 | lamellipodium membrane(GO:0031258) |
| 0.7 | 30.7 | GO:0031228 | intrinsic component of Golgi membrane(GO:0031228) |
| 0.7 | 3.7 | GO:0032541 | cortical endoplasmic reticulum(GO:0032541) |
| 0.7 | 13.8 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.7 | 45.2 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
| 0.7 | 40.2 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.7 | 21.0 | GO:0005921 | gap junction(GO:0005921) |
| 0.7 | 3.5 | GO:0031313 | extrinsic component of endosome membrane(GO:0031313) |
| 0.7 | 32.0 | GO:0030667 | secretory granule membrane(GO:0030667) |
| 0.7 | 6.7 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
| 0.7 | 6.7 | GO:0005964 | phosphorylase kinase complex(GO:0005964) |
| 0.7 | 3.3 | GO:0034750 | Scrib-APC-beta-catenin complex(GO:0034750) |
| 0.7 | 155.2 | GO:0045211 | postsynaptic membrane(GO:0045211) |
| 0.7 | 11.2 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.6 | 6.5 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.6 | 3.9 | GO:0044214 | spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717) |
| 0.6 | 19.2 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.6 | 4.4 | GO:0036021 | endolysosome lumen(GO:0036021) |
| 0.6 | 3.0 | GO:0036396 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
| 0.6 | 4.1 | GO:0060091 | kinocilium(GO:0060091) |
| 0.6 | 12.4 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.6 | 7.8 | GO:0044447 | axoneme part(GO:0044447) |
| 0.5 | 7.6 | GO:0005869 | dynactin complex(GO:0005869) |
| 0.5 | 7.6 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.5 | 3.2 | GO:0060171 | stereocilium membrane(GO:0060171) |
| 0.5 | 19.9 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.5 | 5.7 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.5 | 35.5 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.5 | 1.5 | GO:0097229 | sperm end piece(GO:0097229) |
| 0.5 | 2.0 | GO:0005960 | glycine cleavage complex(GO:0005960) |
| 0.5 | 8.4 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.5 | 28.0 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
| 0.5 | 1.9 | GO:0000145 | exocyst(GO:0000145) |
| 0.5 | 5.0 | GO:0008024 | cyclin/CDK positive transcription elongation factor complex(GO:0008024) |
| 0.4 | 6.6 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
| 0.4 | 3.1 | GO:0031233 | intrinsic component of external side of plasma membrane(GO:0031233) |
| 0.4 | 3.0 | GO:0042627 | chylomicron(GO:0042627) |
| 0.4 | 2.1 | GO:0097169 | AIM2 inflammasome complex(GO:0097169) |
| 0.4 | 7.3 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.4 | 5.9 | GO:0000974 | Prp19 complex(GO:0000974) |
| 0.4 | 13.2 | GO:0035861 | site of double-strand break(GO:0035861) |
| 0.4 | 3.3 | GO:0072487 | MSL complex(GO:0072487) |
| 0.4 | 5.5 | GO:0000778 | condensed nuclear chromosome kinetochore(GO:0000778) |
| 0.4 | 11.1 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.3 | 1.0 | GO:0030312 | external encapsulating structure(GO:0030312) |
| 0.3 | 0.3 | GO:0070195 | growth hormone receptor complex(GO:0070195) |
| 0.3 | 13.8 | GO:0016235 | aggresome(GO:0016235) |
| 0.3 | 5.1 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.3 | 61.5 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.3 | 9.0 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.3 | 6.3 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.3 | 44.7 | GO:0043025 | neuronal cell body(GO:0043025) |
| 0.3 | 1.8 | GO:0070033 | synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) |
| 0.3 | 11.0 | GO:0097014 | axoneme(GO:0005930) ciliary plasm(GO:0097014) |
| 0.3 | 6.0 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.3 | 1.1 | GO:0035838 | growing cell tip(GO:0035838) new growing cell tip(GO:0035841) |
| 0.3 | 21.1 | GO:0035579 | specific granule membrane(GO:0035579) |
| 0.3 | 10.9 | GO:0005604 | basement membrane(GO:0005604) |
| 0.3 | 1.8 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.3 | 26.9 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.3 | 10.5 | GO:0031526 | brush border membrane(GO:0031526) |
| 0.2 | 6.8 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.2 | 5.3 | GO:0051233 | spindle midzone(GO:0051233) |
| 0.2 | 15.1 | GO:0005776 | autophagosome(GO:0005776) |
| 0.2 | 20.3 | GO:0031514 | motile cilium(GO:0031514) |
| 0.2 | 1.5 | GO:0031527 | filopodium membrane(GO:0031527) |
| 0.2 | 3.4 | GO:0031082 | BLOC complex(GO:0031082) |
| 0.2 | 20.2 | GO:0030018 | Z disc(GO:0030018) |
| 0.2 | 2.1 | GO:0035631 | CD40 receptor complex(GO:0035631) |
| 0.2 | 11.2 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.1 | 601.2 | GO:0016021 | integral component of membrane(GO:0016021) |
| 0.1 | 7.6 | GO:0043197 | dendritic spine(GO:0043197) |
| 0.1 | 122.1 | GO:0005615 | extracellular space(GO:0005615) |
| 0.1 | 1.4 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
| 0.1 | 8.7 | GO:0030426 | growth cone(GO:0030426) |
| 0.1 | 0.6 | GO:0030688 | preribosome, small subunit precursor(GO:0030688) |
| 0.1 | 7.9 | GO:0031234 | extrinsic component of cytoplasmic side of plasma membrane(GO:0031234) |
| 0.1 | 2.8 | GO:0044297 | cell body(GO:0044297) |
| 0.1 | 0.6 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.1 | 3.4 | GO:0030136 | clathrin-coated vesicle(GO:0030136) |
| 0.0 | 0.1 | GO:0033063 | DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 16.6 | 83.2 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 14.2 | 42.7 | GO:0032093 | SAM domain binding(GO:0032093) |
| 14.2 | 56.8 | GO:0032408 | MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408) |
| 11.5 | 34.6 | GO:0004584 | dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584) |
| 11.4 | 45.6 | GO:0035373 | chondroitin sulfate proteoglycan binding(GO:0035373) |
| 9.7 | 48.4 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 9.6 | 86.0 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 9.3 | 37.3 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 9.3 | 37.2 | GO:0016880 | glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880) |
| 8.5 | 25.5 | GO:0001641 | group II metabotropic glutamate receptor activity(GO:0001641) |
| 8.4 | 33.8 | GO:0004773 | steryl-sulfatase activity(GO:0004773) |
| 8.2 | 57.5 | GO:0042289 | MHC class II protein binding(GO:0042289) |
| 8.0 | 239.8 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 8.0 | 39.8 | GO:0005157 | macrophage colony-stimulating factor receptor binding(GO:0005157) |
| 7.5 | 22.5 | GO:0016429 | tRNA (adenine-N1-)-methyltransferase activity(GO:0016429) |
| 7.4 | 22.3 | GO:0016497 | substance K receptor activity(GO:0016497) |
| 7.2 | 21.6 | GO:0015389 | pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389) |
| 7.0 | 27.8 | GO:0016639 | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639) |
| 6.9 | 20.7 | GO:1904599 | advanced glycation end-product binding(GO:1904599) |
| 6.8 | 47.3 | GO:0008821 | crossover junction endodeoxyribonuclease activity(GO:0008821) |
| 6.5 | 38.9 | GO:0070004 | cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004) |
| 6.4 | 6.4 | GO:0050682 | AF-2 domain binding(GO:0050682) |
| 6.3 | 25.1 | GO:0047288 | monosialoganglioside sialyltransferase activity(GO:0047288) |
| 6.2 | 18.5 | GO:0047757 | chondroitin-glucuronate 5-epimerase activity(GO:0047757) |
| 6.1 | 36.8 | GO:0047057 | oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057) |
| 6.1 | 67.1 | GO:0032051 | clathrin light chain binding(GO:0032051) |
| 6.1 | 42.6 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
| 6.0 | 24.2 | GO:0097001 | ceramide binding(GO:0097001) |
| 6.0 | 36.1 | GO:0005223 | intracellular cGMP activated cation channel activity(GO:0005223) |
| 6.0 | 17.9 | GO:0004119 | cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) |
| 5.9 | 35.4 | GO:0008273 | calcium, potassium:sodium antiporter activity(GO:0008273) |
| 5.9 | 53.0 | GO:0031685 | adenosine receptor binding(GO:0031685) |
| 5.8 | 17.3 | GO:0061629 | RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629) |
| 5.6 | 22.5 | GO:0035939 | microsatellite binding(GO:0035939) |
| 5.4 | 16.2 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
| 5.1 | 10.2 | GO:0016890 | site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890) |
| 5.0 | 60.4 | GO:0019911 | structural constituent of myelin sheath(GO:0019911) |
| 5.0 | 35.1 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 4.9 | 39.5 | GO:0015185 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185) |
| 4.9 | 19.7 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
| 4.9 | 24.6 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
| 4.7 | 14.2 | GO:0004878 | complement component C5a receptor activity(GO:0004878) |
| 4.7 | 9.3 | GO:0005222 | intracellular cAMP activated cation channel activity(GO:0005222) |
| 4.5 | 18.1 | GO:0070051 | fibrinogen binding(GO:0070051) |
| 4.5 | 36.2 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
| 4.3 | 8.6 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 4.2 | 25.5 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 4.2 | 25.2 | GO:0032038 | myosin II heavy chain binding(GO:0032038) |
| 4.1 | 12.4 | GO:0008900 | hydrogen:potassium-exchanging ATPase activity(GO:0008900) |
| 4.1 | 24.6 | GO:0051373 | FATZ binding(GO:0051373) |
| 4.0 | 24.1 | GO:0030172 | troponin C binding(GO:0030172) |
| 3.9 | 27.5 | GO:0043533 | inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533) |
| 3.8 | 11.4 | GO:0046997 | sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997) |
| 3.8 | 49.0 | GO:0004705 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 3.8 | 127.8 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 3.7 | 11.0 | GO:0070052 | collagen V binding(GO:0070052) |
| 3.6 | 18.2 | GO:0004991 | parathyroid hormone receptor activity(GO:0004991) |
| 3.6 | 51.0 | GO:0022820 | potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820) |
| 3.6 | 10.9 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 3.6 | 50.5 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 3.6 | 28.6 | GO:0005220 | inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220) |
| 3.6 | 21.4 | GO:0060961 | phospholipase D inhibitor activity(GO:0060961) |
| 3.5 | 10.5 | GO:0016833 | oxo-acid-lyase activity(GO:0016833) |
| 3.5 | 20.9 | GO:0005127 | ciliary neurotrophic factor receptor binding(GO:0005127) |
| 3.3 | 13.4 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
| 3.3 | 16.5 | GO:0032795 | heterotrimeric G-protein binding(GO:0032795) |
| 3.3 | 9.9 | GO:0070735 | protein-glycine ligase activity(GO:0070735) |
| 3.3 | 16.4 | GO:0045174 | glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610) |
| 3.3 | 55.5 | GO:0019864 | IgG binding(GO:0019864) |
| 3.2 | 12.8 | GO:0016495 | C-X3-C chemokine receptor activity(GO:0016495) |
| 3.2 | 12.6 | GO:0004769 | steroid delta-isomerase activity(GO:0004769) |
| 3.1 | 28.3 | GO:0046975 | histone methyltransferase activity (H3-K36 specific)(GO:0046975) |
| 3.1 | 34.5 | GO:0005391 | sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556) |
| 3.1 | 28.0 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
| 3.1 | 9.2 | GO:0004613 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 3.0 | 21.2 | GO:0086089 | voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089) |
| 3.0 | 36.3 | GO:0003996 | acyl-CoA ligase activity(GO:0003996) |
| 3.0 | 9.0 | GO:0004961 | thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961) |
| 3.0 | 30.0 | GO:0015386 | sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 3.0 | 8.9 | GO:0004796 | thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134) |
| 2.9 | 8.7 | GO:0035662 | Toll-like receptor 4 binding(GO:0035662) |
| 2.9 | 28.7 | GO:0005237 | inhibitory extracellular ligand-gated ion channel activity(GO:0005237) |
| 2.8 | 11.3 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 2.8 | 16.7 | GO:0015333 | peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897) |
| 2.7 | 10.9 | GO:0001640 | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988) |
| 2.7 | 21.5 | GO:0005436 | sodium:phosphate symporter activity(GO:0005436) |
| 2.6 | 10.5 | GO:1904493 | Ac-Asp-Glu binding(GO:1904492) tetrahydrofolyl-poly(glutamate) polymer binding(GO:1904493) |
| 2.6 | 56.8 | GO:0019104 | DNA N-glycosylase activity(GO:0019104) |
| 2.6 | 12.9 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 2.6 | 41.0 | GO:0031821 | G-protein coupled serotonin receptor binding(GO:0031821) |
| 2.5 | 12.5 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 2.5 | 35.0 | GO:0003691 | double-stranded telomeric DNA binding(GO:0003691) |
| 2.4 | 26.9 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
| 2.4 | 26.7 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
| 2.4 | 33.8 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 2.4 | 7.2 | GO:0005026 | transforming growth factor beta receptor activity, type II(GO:0005026) |
| 2.4 | 7.1 | GO:0030272 | 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272) |
| 2.3 | 9.4 | GO:0015254 | glycerol channel activity(GO:0015254) |
| 2.3 | 7.0 | GO:0004382 | guanosine-diphosphatase activity(GO:0004382) |
| 2.3 | 20.8 | GO:0070697 | activin receptor binding(GO:0070697) |
| 2.3 | 25.1 | GO:0016755 | transferase activity, transferring amino-acyl groups(GO:0016755) |
| 2.3 | 9.1 | GO:0004461 | lactose synthase activity(GO:0004461) |
| 2.3 | 70.4 | GO:0005001 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 2.3 | 69.8 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
| 2.2 | 40.3 | GO:0038191 | neuropilin binding(GO:0038191) |
| 2.2 | 8.9 | GO:0008281 | sulfonylurea receptor activity(GO:0008281) |
| 2.2 | 8.9 | GO:0042799 | histone methyltransferase activity (H4-K20 specific)(GO:0042799) |
| 2.2 | 11.2 | GO:0004370 | glycerol kinase activity(GO:0004370) |
| 2.2 | 20.1 | GO:0004117 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) |
| 2.2 | 10.9 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
| 2.2 | 6.5 | GO:0005055 | laminin receptor activity(GO:0005055) |
| 2.2 | 6.5 | GO:0086059 | voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059) |
| 2.2 | 30.3 | GO:0046790 | virion binding(GO:0046790) |
| 2.2 | 8.6 | GO:0004341 | gluconolactonase activity(GO:0004341) |
| 2.2 | 129.1 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 2.1 | 51.4 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 2.1 | 14.9 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 2.1 | 12.4 | GO:0004359 | glutaminase activity(GO:0004359) |
| 2.1 | 22.6 | GO:0051525 | NFAT protein binding(GO:0051525) |
| 2.1 | 43.2 | GO:0004185 | serine-type carboxypeptidase activity(GO:0004185) |
| 2.0 | 32.5 | GO:0031702 | type 1 angiotensin receptor binding(GO:0031702) |
| 2.0 | 12.2 | GO:0090554 | phosphatidylcholine-translocating ATPase activity(GO:0090554) |
| 2.0 | 4.1 | GO:0052870 | tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259) |
| 2.0 | 12.0 | GO:0004699 | calcium-independent protein kinase C activity(GO:0004699) |
| 2.0 | 6.0 | GO:0035375 | zymogen binding(GO:0035375) |
| 2.0 | 9.9 | GO:0070653 | high-density lipoprotein particle receptor binding(GO:0070653) |
| 2.0 | 5.9 | GO:0030158 | protein xylosyltransferase activity(GO:0030158) |
| 1.9 | 29.0 | GO:0004985 | opioid receptor activity(GO:0004985) |
| 1.9 | 36.6 | GO:0048156 | tau protein binding(GO:0048156) |
| 1.9 | 119.1 | GO:0030507 | spectrin binding(GO:0030507) |
| 1.9 | 5.7 | GO:0031013 | troponin I binding(GO:0031013) |
| 1.9 | 13.3 | GO:0000182 | rDNA binding(GO:0000182) |
| 1.9 | 74.2 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 1.9 | 34.1 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
| 1.9 | 18.9 | GO:0008131 | primary amine oxidase activity(GO:0008131) |
| 1.9 | 30.2 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 1.9 | 9.4 | GO:0050436 | microfibril binding(GO:0050436) |
| 1.9 | 5.7 | GO:0004047 | aminomethyltransferase activity(GO:0004047) |
| 1.9 | 5.6 | GO:0003680 | AT DNA binding(GO:0003680) |
| 1.9 | 104.1 | GO:0017080 | sodium channel regulator activity(GO:0017080) |
| 1.9 | 3.7 | GO:0008142 | oxysterol binding(GO:0008142) |
| 1.8 | 7.4 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 1.8 | 25.8 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 1.8 | 10.9 | GO:0004882 | androgen receptor activity(GO:0004882) |
| 1.8 | 32.8 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 1.8 | 3.6 | GO:0004995 | tachykinin receptor activity(GO:0004995) |
| 1.8 | 7.2 | GO:0004909 | interleukin-1, Type I, activating receptor activity(GO:0004909) |
| 1.8 | 5.3 | GO:0004782 | sulfinoalanine decarboxylase activity(GO:0004782) |
| 1.8 | 28.1 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 1.8 | 3.5 | GO:0042806 | fucose binding(GO:0042806) |
| 1.7 | 45.4 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 1.7 | 5.2 | GO:0010521 | telomerase inhibitor activity(GO:0010521) |
| 1.7 | 41.4 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 1.7 | 15.2 | GO:0047144 | 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144) |
| 1.7 | 5.0 | GO:0004937 | alpha1-adrenergic receptor activity(GO:0004937) |
| 1.7 | 6.7 | GO:0050119 | N-acetylglucosamine deacetylase activity(GO:0050119) |
| 1.7 | 21.8 | GO:0019865 | immunoglobulin binding(GO:0019865) |
| 1.7 | 8.3 | GO:0047238 | glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238) |
| 1.7 | 13.3 | GO:0004111 | creatine kinase activity(GO:0004111) |
| 1.7 | 6.6 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
| 1.7 | 5.0 | GO:0004060 | arylamine N-acetyltransferase activity(GO:0004060) |
| 1.6 | 24.7 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
| 1.6 | 4.9 | GO:0047325 | inositol tetrakisphosphate 1-kinase activity(GO:0047325) inositol tetrakisphosphate kinase activity(GO:0051765) inositol-1,3,4-trisphosphate 6-kinase activity(GO:0052725) inositol-1,3,4-trisphosphate 5-kinase activity(GO:0052726) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) |
| 1.6 | 4.8 | GO:0004998 | transferrin receptor activity(GO:0004998) |
| 1.6 | 14.5 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
| 1.6 | 17.5 | GO:0050811 | GABA receptor binding(GO:0050811) |
| 1.6 | 12.7 | GO:0004024 | alcohol dehydrogenase activity, zinc-dependent(GO:0004024) |
| 1.6 | 14.3 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
| 1.6 | 25.3 | GO:0070411 | I-SMAD binding(GO:0070411) |
| 1.6 | 7.9 | GO:0043546 | molybdopterin cofactor binding(GO:0043546) |
| 1.6 | 9.5 | GO:0004614 | phosphoglucomutase activity(GO:0004614) |
| 1.5 | 10.8 | GO:0004797 | deoxycytidine kinase activity(GO:0004137) thymidine kinase activity(GO:0004797) |
| 1.5 | 9.2 | GO:0042392 | sphingosine-1-phosphate phosphatase activity(GO:0042392) |
| 1.5 | 18.4 | GO:0038132 | neuregulin binding(GO:0038132) |
| 1.5 | 7.5 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 1.5 | 13.5 | GO:0016799 | hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799) |
| 1.5 | 3.0 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 1.5 | 44.7 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 1.5 | 5.9 | GO:0005412 | glucose:sodium symporter activity(GO:0005412) |
| 1.5 | 5.9 | GO:0000026 | alpha-1,2-mannosyltransferase activity(GO:0000026) |
| 1.5 | 8.8 | GO:0018685 | alkane 1-monooxygenase activity(GO:0018685) |
| 1.4 | 181.1 | GO:0003707 | steroid hormone receptor activity(GO:0003707) |
| 1.4 | 12.9 | GO:0034235 | GPI anchor binding(GO:0034235) |
| 1.4 | 5.7 | GO:0002046 | opsin binding(GO:0002046) |
| 1.4 | 5.7 | GO:0046592 | polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901) |
| 1.4 | 40.0 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 1.4 | 396.2 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 1.4 | 8.5 | GO:0038062 | protein tyrosine kinase collagen receptor activity(GO:0038062) |
| 1.4 | 5.7 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 1.4 | 8.5 | GO:0045029 | UDP-activated nucleotide receptor activity(GO:0045029) |
| 1.4 | 18.3 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 1.4 | 4.2 | GO:0047751 | 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751) |
| 1.4 | 7.0 | GO:0042610 | CD8 receptor binding(GO:0042610) |
| 1.4 | 4.2 | GO:1990190 | peptide-glutamate-N-acetyltransferase activity(GO:1990190) |
| 1.4 | 11.2 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 1.4 | 8.3 | GO:0039552 | RIG-I binding(GO:0039552) |
| 1.4 | 10.9 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 1.4 | 15.0 | GO:0004645 | phosphorylase activity(GO:0004645) |
| 1.4 | 14.9 | GO:0032454 | histone demethylase activity (H3-K9 specific)(GO:0032454) |
| 1.4 | 4.1 | GO:0008523 | sodium-dependent multivitamin transmembrane transporter activity(GO:0008523) |
| 1.3 | 24.3 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 1.3 | 10.8 | GO:0016015 | morphogen activity(GO:0016015) |
| 1.3 | 21.4 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 1.3 | 10.7 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 1.3 | 19.8 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
| 1.3 | 3.9 | GO:0016401 | palmitoyl-CoA oxidase activity(GO:0016401) |
| 1.3 | 7.8 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 1.3 | 19.6 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
| 1.3 | 6.5 | GO:0033695 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
| 1.3 | 44.9 | GO:0017075 | syntaxin-1 binding(GO:0017075) |
| 1.2 | 3.7 | GO:0004980 | melanocyte-stimulating hormone receptor activity(GO:0004980) |
| 1.2 | 44.9 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 1.2 | 7.5 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 1.2 | 12.4 | GO:0005549 | odorant binding(GO:0005549) |
| 1.2 | 19.7 | GO:0008320 | protein transmembrane transporter activity(GO:0008320) |
| 1.2 | 8.6 | GO:0070891 | lipoteichoic acid binding(GO:0070891) |
| 1.2 | 22.0 | GO:0005024 | transforming growth factor beta-activated receptor activity(GO:0005024) |
| 1.2 | 22.0 | GO:0005248 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 1.2 | 4.9 | GO:0015220 | choline transmembrane transporter activity(GO:0015220) |
| 1.2 | 14.6 | GO:0015174 | basic amino acid transmembrane transporter activity(GO:0015174) |
| 1.2 | 4.8 | GO:0042923 | neuropeptide binding(GO:0042923) |
| 1.2 | 4.7 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
| 1.2 | 15.4 | GO:0019103 | pyrimidine nucleotide binding(GO:0019103) |
| 1.2 | 7.1 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 1.2 | 25.9 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) |
| 1.2 | 9.3 | GO:0003726 | double-stranded RNA adenosine deaminase activity(GO:0003726) |
| 1.2 | 4.6 | GO:0004925 | prolactin receptor activity(GO:0004925) |
| 1.2 | 17.3 | GO:0044213 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213) |
| 1.1 | 3.4 | GO:0047493 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
| 1.1 | 4.5 | GO:0001025 | RNA polymerase III transcription factor binding(GO:0001025) |
| 1.1 | 10.1 | GO:0051425 | PTB domain binding(GO:0051425) |
| 1.1 | 4.5 | GO:0034353 | RNA pyrophosphohydrolase activity(GO:0034353) |
| 1.1 | 13.4 | GO:0031432 | titin binding(GO:0031432) |
| 1.1 | 6.7 | GO:0004689 | phosphorylase kinase activity(GO:0004689) |
| 1.1 | 9.9 | GO:0043426 | MRF binding(GO:0043426) |
| 1.1 | 4.3 | GO:0030628 | pre-mRNA 3'-splice site binding(GO:0030628) |
| 1.1 | 22.7 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 1.1 | 21.6 | GO:0005522 | profilin binding(GO:0005522) |
| 1.1 | 3.2 | GO:0004967 | glucagon receptor activity(GO:0004967) |
| 1.1 | 13.8 | GO:0017110 | nucleoside-diphosphatase activity(GO:0017110) |
| 1.1 | 8.5 | GO:0032794 | GTPase activating protein binding(GO:0032794) |
| 1.1 | 14.9 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 1.1 | 9.5 | GO:0047429 | nucleoside-triphosphate diphosphatase activity(GO:0047429) |
| 1.1 | 9.5 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 1.0 | 3.1 | GO:0017129 | triglyceride binding(GO:0017129) |
| 1.0 | 3.0 | GO:0016422 | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422) |
| 1.0 | 11.0 | GO:0043225 | anion transmembrane-transporting ATPase activity(GO:0043225) |
| 1.0 | 15.0 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 1.0 | 51.1 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 1.0 | 9.0 | GO:0005384 | manganese ion transmembrane transporter activity(GO:0005384) |
| 1.0 | 42.4 | GO:0017112 | Rab guanyl-nucleotide exchange factor activity(GO:0017112) |
| 1.0 | 4.9 | GO:0004905 | type I interferon receptor activity(GO:0004905) |
| 1.0 | 7.8 | GO:0003910 | DNA ligase (ATP) activity(GO:0003910) |
| 1.0 | 13.5 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 1.0 | 9.6 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 1.0 | 12.5 | GO:0036374 | glutathione hydrolase activity(GO:0036374) |
| 1.0 | 27.7 | GO:0008066 | glutamate receptor activity(GO:0008066) |
| 1.0 | 6.7 | GO:0043812 | phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812) |
| 0.9 | 12.3 | GO:0070700 | BMP receptor binding(GO:0070700) |
| 0.9 | 12.3 | GO:0008391 | arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392) |
| 0.9 | 15.0 | GO:0004716 | receptor signaling protein tyrosine kinase activity(GO:0004716) |
| 0.9 | 6.5 | GO:0004075 | biotin carboxylase activity(GO:0004075) |
| 0.9 | 9.3 | GO:0032027 | myosin light chain binding(GO:0032027) |
| 0.9 | 15.7 | GO:0005520 | insulin-like growth factor binding(GO:0005520) |
| 0.9 | 3.7 | GO:0097108 | hedgehog family protein binding(GO:0097108) |
| 0.9 | 15.6 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.9 | 22.0 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
| 0.9 | 14.5 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
| 0.9 | 20.9 | GO:0043014 | alpha-tubulin binding(GO:0043014) |
| 0.9 | 4.5 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
| 0.9 | 8.1 | GO:0001871 | pattern binding(GO:0001871) polysaccharide binding(GO:0030247) |
| 0.9 | 6.3 | GO:0019826 | oxygen sensor activity(GO:0019826) |
| 0.9 | 16.9 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707) |
| 0.9 | 6.2 | GO:0001225 | RNA polymerase II transcription cofactor binding(GO:0001224) RNA polymerase II transcription coactivator binding(GO:0001225) |
| 0.9 | 5.3 | GO:0032052 | bile acid binding(GO:0032052) |
| 0.9 | 9.7 | GO:1904264 | ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264) |
| 0.9 | 73.5 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.9 | 82.0 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.9 | 19.1 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
| 0.8 | 5.9 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 0.8 | 4.2 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 0.8 | 5.0 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
| 0.8 | 6.6 | GO:0031697 | beta-1 adrenergic receptor binding(GO:0031697) G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812) |
| 0.8 | 98.1 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.8 | 8.2 | GO:0001223 | transcription coactivator binding(GO:0001223) |
| 0.8 | 4.9 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
| 0.8 | 9.7 | GO:0032395 | MHC class II receptor activity(GO:0032395) |
| 0.8 | 10.5 | GO:0019841 | retinol binding(GO:0019841) |
| 0.8 | 3.2 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
| 0.8 | 2.3 | GO:0047783 | steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783) |
| 0.8 | 5.4 | GO:0030250 | cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250) |
| 0.8 | 18.6 | GO:0070402 | NADPH binding(GO:0070402) |
| 0.8 | 5.4 | GO:0004957 | prostaglandin E receptor activity(GO:0004957) |
| 0.8 | 52.2 | GO:0070888 | E-box binding(GO:0070888) |
| 0.8 | 3.0 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.8 | 15.0 | GO:0043325 | phosphatidylinositol-3,4-bisphosphate binding(GO:0043325) |
| 0.7 | 6.7 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
| 0.7 | 2.2 | GO:0098640 | integrin binding involved in cell-matrix adhesion(GO:0098640) |
| 0.7 | 6.6 | GO:0019870 | potassium channel inhibitor activity(GO:0019870) |
| 0.7 | 10.2 | GO:0004551 | nucleotide diphosphatase activity(GO:0004551) |
| 0.7 | 7.9 | GO:0005078 | MAP-kinase scaffold activity(GO:0005078) |
| 0.7 | 10.0 | GO:0005402 | sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402) |
| 0.7 | 10.0 | GO:0032183 | SUMO binding(GO:0032183) |
| 0.7 | 8.5 | GO:0005344 | oxygen transporter activity(GO:0005344) |
| 0.7 | 6.4 | GO:0043274 | phospholipase binding(GO:0043274) |
| 0.7 | 16.3 | GO:0070403 | NAD+ binding(GO:0070403) |
| 0.7 | 18.4 | GO:0008519 | ammonium transmembrane transporter activity(GO:0008519) |
| 0.7 | 4.2 | GO:0047894 | flavonol 3-sulfotransferase activity(GO:0047894) |
| 0.7 | 4.2 | GO:0017060 | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity(GO:0017060) |
| 0.7 | 10.6 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.7 | 2.1 | GO:0019150 | D-ribulokinase activity(GO:0019150) |
| 0.7 | 7.7 | GO:0030280 | structural constituent of epidermis(GO:0030280) |
| 0.7 | 9.8 | GO:0000146 | microfilament motor activity(GO:0000146) |
| 0.7 | 6.3 | GO:0010385 | double-stranded methylated DNA binding(GO:0010385) |
| 0.7 | 27.0 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.7 | 222.9 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.7 | 4.1 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.7 | 8.2 | GO:0017081 | chloride channel regulator activity(GO:0017081) |
| 0.7 | 3.4 | GO:0004045 | aminoacyl-tRNA hydrolase activity(GO:0004045) |
| 0.7 | 15.6 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
| 0.7 | 23.6 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.7 | 2.7 | GO:0048248 | CXCR3 chemokine receptor binding(GO:0048248) |
| 0.6 | 3.9 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
| 0.6 | 22.7 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.6 | 23.3 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.6 | 3.1 | GO:0015057 | thrombin receptor activity(GO:0015057) |
| 0.6 | 10.5 | GO:0016493 | C-C chemokine receptor activity(GO:0016493) |
| 0.6 | 4.3 | GO:1903763 | gap junction channel activity involved in cell communication by electrical coupling(GO:1903763) |
| 0.6 | 8.3 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.6 | 2.4 | GO:0004911 | interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976) |
| 0.6 | 24.9 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.6 | 18.2 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.6 | 2.3 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 0.6 | 15.1 | GO:0042605 | peptide antigen binding(GO:0042605) |
| 0.6 | 4.1 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.6 | 1.7 | GO:0036505 | prosaposin receptor activity(GO:0036505) |
| 0.6 | 14.2 | GO:0102391 | decanoate--CoA ligase activity(GO:0102391) |
| 0.6 | 8.5 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.6 | 5.6 | GO:0032138 | single base insertion or deletion binding(GO:0032138) |
| 0.6 | 3.3 | GO:0036122 | BMP binding(GO:0036122) |
| 0.6 | 13.9 | GO:0004115 | 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115) |
| 0.6 | 3.9 | GO:0016406 | carnitine O-acyltransferase activity(GO:0016406) |
| 0.6 | 8.8 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
| 0.6 | 3.3 | GO:0004740 | pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740) |
| 0.5 | 13.1 | GO:0070840 | dynein complex binding(GO:0070840) |
| 0.5 | 3.3 | GO:0070569 | uridylyltransferase activity(GO:0070569) |
| 0.5 | 14.7 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.5 | 16.0 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.5 | 4.8 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.5 | 5.3 | GO:0015250 | water channel activity(GO:0015250) |
| 0.5 | 3.6 | GO:0030160 | GKAP/Homer scaffold activity(GO:0030160) |
| 0.5 | 3.6 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 0.5 | 31.7 | GO:0016820 | hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances(GO:0016820) |
| 0.5 | 3.1 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
| 0.5 | 10.1 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
| 0.5 | 3.5 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
| 0.5 | 6.0 | GO:0008376 | acetylgalactosaminyltransferase activity(GO:0008376) |
| 0.5 | 34.6 | GO:0005249 | voltage-gated potassium channel activity(GO:0005249) |
| 0.5 | 5.0 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.5 | 19.2 | GO:0001102 | RNA polymerase II activating transcription factor binding(GO:0001102) |
| 0.5 | 2.5 | GO:0015184 | L-cystine transmembrane transporter activity(GO:0015184) |
| 0.5 | 6.9 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
| 0.5 | 2.4 | GO:0004530 | deoxyribonuclease I activity(GO:0004530) |
| 0.5 | 5.8 | GO:0035325 | Toll-like receptor binding(GO:0035325) |
| 0.5 | 3.3 | GO:0017147 | Wnt-protein binding(GO:0017147) |
| 0.5 | 5.1 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
| 0.5 | 5.0 | GO:0004931 | extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) |
| 0.5 | 3.2 | GO:0016714 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) |
| 0.5 | 5.0 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
| 0.4 | 13.4 | GO:0031683 | G-protein beta/gamma-subunit complex binding(GO:0031683) |
| 0.4 | 2.5 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.4 | 2.1 | GO:0004392 | heme oxygenase (decyclizing) activity(GO:0004392) |
| 0.4 | 8.3 | GO:0016709 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709) |
| 0.4 | 7.0 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.4 | 30.9 | GO:0008080 | N-acetyltransferase activity(GO:0008080) |
| 0.4 | 10.4 | GO:0005521 | lamin binding(GO:0005521) |
| 0.4 | 4.8 | GO:0008527 | taste receptor activity(GO:0008527) |
| 0.4 | 10.5 | GO:0000983 | transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983) |
| 0.4 | 6.5 | GO:0005542 | folic acid binding(GO:0005542) |
| 0.4 | 3.1 | GO:0050693 | LBD domain binding(GO:0050693) |
| 0.4 | 1.5 | GO:0005163 | nerve growth factor receptor binding(GO:0005163) |
| 0.4 | 35.6 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.4 | 1.1 | GO:0015377 | cation:chloride symporter activity(GO:0015377) |
| 0.4 | 4.6 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.4 | 4.2 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
| 0.3 | 6.8 | GO:0032451 | demethylase activity(GO:0032451) |
| 0.3 | 6.8 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.3 | 2.3 | GO:0003828 | alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) |
| 0.3 | 7.7 | GO:0033613 | activating transcription factor binding(GO:0033613) |
| 0.3 | 1.6 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.3 | 1.9 | GO:0015172 | L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172) |
| 0.3 | 1.9 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.3 | 7.3 | GO:0008081 | phosphoric diester hydrolase activity(GO:0008081) |
| 0.3 | 3.2 | GO:0008429 | phosphatidylethanolamine binding(GO:0008429) |
| 0.3 | 24.0 | GO:0017048 | Rho GTPase binding(GO:0017048) |
| 0.3 | 2.3 | GO:0031404 | chloride ion binding(GO:0031404) |
| 0.3 | 2.1 | GO:0045159 | myosin II binding(GO:0045159) |
| 0.3 | 1.6 | GO:0030369 | ICAM-3 receptor activity(GO:0030369) |
| 0.3 | 3.9 | GO:0031210 | phosphatidylcholine binding(GO:0031210) |
| 0.3 | 3.8 | GO:0005132 | type I interferon receptor binding(GO:0005132) |
| 0.2 | 3.3 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.2 | 15.1 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.2 | 2.3 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.2 | 8.3 | GO:0017069 | snRNA binding(GO:0017069) |
| 0.2 | 3.7 | GO:0051371 | muscle alpha-actinin binding(GO:0051371) |
| 0.2 | 19.9 | GO:0020037 | heme binding(GO:0020037) |
| 0.2 | 6.1 | GO:0015035 | protein disulfide oxidoreductase activity(GO:0015035) |
| 0.2 | 8.6 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.2 | 3.7 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.2 | 1.5 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
| 0.2 | 1.1 | GO:0005497 | androgen binding(GO:0005497) |
| 0.2 | 1.3 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
| 0.2 | 5.7 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.2 | 6.2 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.2 | 2.3 | GO:0008195 | phosphatidate phosphatase activity(GO:0008195) |
| 0.2 | 4.4 | GO:0030331 | estrogen receptor binding(GO:0030331) |
| 0.2 | 2.2 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.2 | 1.4 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
| 0.2 | 3.5 | GO:0005545 | 1-phosphatidylinositol binding(GO:0005545) |
| 0.2 | 4.0 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.2 | 0.7 | GO:0004948 | calcitonin receptor activity(GO:0004948) |
| 0.2 | 6.3 | GO:0016279 | lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279) |
| 0.2 | 1.5 | GO:0004396 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
| 0.2 | 18.6 | GO:0005088 | Ras guanyl-nucleotide exchange factor activity(GO:0005088) |
| 0.2 | 5.0 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.2 | 5.3 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
| 0.2 | 3.0 | GO:0017171 | serine hydrolase activity(GO:0017171) |
| 0.2 | 2.2 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.1 | 1.1 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.1 | 8.1 | GO:0005179 | hormone activity(GO:0005179) |
| 0.1 | 2.5 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
| 0.1 | 4.2 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.1 | 2.9 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.1 | 3.1 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.1 | 0.6 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 8.9 | GO:0047485 | protein N-terminus binding(GO:0047485) |
| 0.1 | 3.6 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.1 | 3.1 | GO:0016706 | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706) |
| 0.1 | 0.5 | GO:0035800 | deubiquitinase activator activity(GO:0035800) |
| 0.1 | 1.0 | GO:0004311 | farnesyltranstransferase activity(GO:0004311) |
| 0.1 | 3.1 | GO:0032934 | sterol binding(GO:0032934) |
| 0.1 | 1.1 | GO:0004559 | alpha-mannosidase activity(GO:0004559) |
| 0.1 | 35.4 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.1 | 0.3 | GO:0004609 | phosphatidylserine decarboxylase activity(GO:0004609) |
| 0.1 | 1.0 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 3.4 | GO:0016209 | antioxidant activity(GO:0016209) |
| 0.1 | 0.3 | GO:0008948 | malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948) |
| 0.0 | 60.3 | GO:0003700 | nucleic acid binding transcription factor activity(GO:0001071) transcription factor activity, sequence-specific DNA binding(GO:0003700) |
| 0.0 | 0.3 | GO:0032393 | MHC class I receptor activity(GO:0032393) |
| 0.0 | 0.8 | GO:0051219 | phosphoprotein binding(GO:0051219) |
| 0.0 | 0.2 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.0 | 0.6 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
| 0.0 | 1.0 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.0 | 0.4 | GO:0005343 | organic acid:sodium symporter activity(GO:0005343) |
| 0.0 | 0.3 | GO:0004303 | estradiol 17-beta-dehydrogenase activity(GO:0004303) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 10.0 | 10.0 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 2.8 | 78.7 | PID S1P S1P4 PATHWAY | S1P4 pathway |
| 1.8 | 102.0 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 1.6 | 66.5 | ST WNT CA2 CYCLIC GMP PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 1.5 | 48.2 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
| 1.5 | 58.6 | PID RAS PATHWAY | Regulation of Ras family activation |
| 1.4 | 18.4 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 1.4 | 66.9 | ST ADRENERGIC | Adrenergic Pathway |
| 1.3 | 12.1 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 1.3 | 27.2 | PID FAS PATHWAY | FAS (CD95) signaling pathway |
| 1.3 | 21.5 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 1.3 | 55.4 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 1.2 | 4.7 | PID CD8 TCR PATHWAY | TCR signaling in naïve CD8+ T cells |
| 1.1 | 6.8 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
| 1.1 | 13.5 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 1.1 | 23.9 | PID AVB3 OPN PATHWAY | Osteopontin-mediated events |
| 1.0 | 8.2 | ST JAK STAT PATHWAY | Jak-STAT Pathway |
| 1.0 | 13.2 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 1.0 | 14.0 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
| 0.9 | 18.1 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.9 | 46.7 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.9 | 19.2 | PID CONE PATHWAY | Visual signal transduction: Cones |
| 0.9 | 16.4 | PID CIRCADIAN PATHWAY | Circadian rhythm pathway |
| 0.8 | 21.6 | PID P38 ALPHA BETA PATHWAY | Regulation of p38-alpha and p38-beta |
| 0.8 | 34.7 | PID REELIN PATHWAY | Reelin signaling pathway |
| 0.8 | 7.0 | PID A6B1 A6B4 INTEGRIN PATHWAY | a6b1 and a6b4 Integrin signaling |
| 0.8 | 28.2 | PID INTEGRIN CS PATHWAY | Integrin family cell surface interactions |
| 0.7 | 4.5 | PID THROMBIN PAR4 PATHWAY | PAR4-mediated thrombin signaling events |
| 0.7 | 11.5 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.7 | 36.5 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.7 | 15.3 | PID PI3K PLC TRK PATHWAY | Trk receptor signaling mediated by PI3K and PLC-gamma |
| 0.7 | 35.5 | PID RHOA PATHWAY | RhoA signaling pathway |
| 0.7 | 14.9 | PID SYNDECAN 3 PATHWAY | Syndecan-3-mediated signaling events |
| 0.7 | 23.1 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.6 | 4.9 | ST G ALPHA I PATHWAY | G alpha i Pathway |
| 0.6 | 17.6 | PID ALPHA SYNUCLEIN PATHWAY | Alpha-synuclein signaling |
| 0.6 | 15.6 | PID CD40 PATHWAY | CD40/CD40L signaling |
| 0.6 | 10.3 | PID EPHRINB REV PATHWAY | Ephrin B reverse signaling |
| 0.6 | 10.2 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.6 | 9.0 | PID IL27 PATHWAY | IL27-mediated signaling events |
| 0.6 | 15.8 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.6 | 5.1 | PID S1P S1P3 PATHWAY | S1P3 pathway |
| 0.5 | 39.9 | PID LKB1 PATHWAY | LKB1 signaling events |
| 0.5 | 9.2 | PID PRL SIGNALING EVENTS PATHWAY | Signaling events mediated by PRL |
| 0.5 | 10.2 | PID IFNG PATHWAY | IFN-gamma pathway |
| 0.5 | 7.5 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.5 | 12.2 | PID HIF1A PATHWAY | Hypoxic and oxygen homeostasis regulation of HIF-1-alpha |
| 0.5 | 9.5 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.5 | 18.4 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.5 | 25.2 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.5 | 38.4 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.5 | 11.3 | PID TXA2PATHWAY | Thromboxane A2 receptor signaling |
| 0.5 | 6.2 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.5 | 11.2 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.5 | 15.5 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.5 | 2.0 | PID ECADHERIN KERATINOCYTE PATHWAY | E-cadherin signaling in keratinocytes |
| 0.5 | 7.8 | PID PI3KCI AKT PATHWAY | Class I PI3K signaling events mediated by Akt |
| 0.5 | 16.9 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.5 | 24.7 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.5 | 26.1 | PID FGF PATHWAY | FGF signaling pathway |
| 0.5 | 15.4 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
| 0.5 | 19.9 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.5 | 7.3 | PID EPO PATHWAY | EPO signaling pathway |
| 0.4 | 18.1 | PID PI3KCI PATHWAY | Class I PI3K signaling events |
| 0.4 | 10.9 | PID INSULIN PATHWAY | Insulin Pathway |
| 0.4 | 3.5 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.4 | 24.5 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.4 | 20.7 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
| 0.4 | 3.4 | SA PROGRAMMED CELL DEATH | Programmed cell death, or apoptosis, eliminates damaged or unneeded cells. |
| 0.4 | 2.7 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.4 | 10.6 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.4 | 36.4 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.4 | 7.8 | PID NFKAPPAB CANONICAL PATHWAY | Canonical NF-kappaB pathway |
| 0.3 | 8.7 | PID LYSOPHOSPHOLIPID PATHWAY | LPA receptor mediated events |
| 0.3 | 3.4 | PID IL2 PI3K PATHWAY | IL2 signaling events mediated by PI3K |
| 0.3 | 7.1 | PID TNF PATHWAY | TNF receptor signaling pathway |
| 0.3 | 6.4 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.3 | 4.7 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
| 0.3 | 68.1 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.3 | 5.6 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.3 | 53.6 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.3 | 8.4 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.3 | 71.1 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.3 | 3.4 | ST PHOSPHOINOSITIDE 3 KINASE PATHWAY | PI3K Pathway |
| 0.2 | 5.2 | PID EPHB FWD PATHWAY | EPHB forward signaling |
| 0.2 | 7.7 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.2 | 3.0 | PID IL3 PATHWAY | IL3-mediated signaling events |
| 0.2 | 2.2 | PID VEGFR1 PATHWAY | VEGFR1 specific signals |
| 0.2 | 3.8 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.2 | 0.8 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.2 | 7.4 | PID CDC42 REG PATHWAY | Regulation of CDC42 activity |
| 0.2 | 3.4 | ST WNT BETA CATENIN PATHWAY | Wnt/beta-catenin Pathway |
| 0.1 | 2.4 | PID IL6 7 PATHWAY | IL6-mediated signaling events |
| 0.1 | 3.5 | PID FAK PATHWAY | Signaling events mediated by focal adhesion kinase |
| 0.1 | 1.5 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.1 | 0.3 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.1 | 0.4 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.1 | 2.9 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 1.3 | PID ALK2 PATHWAY | ALK2 signaling events |
| 0.1 | 0.7 | PID BETA CATENIN DEG PATHWAY | Degradation of beta catenin |
| 0.1 | 0.3 | PID AR NONGENOMIC PATHWAY | Nongenotropic Androgen signaling |
| 0.1 | 0.8 | PID INSULIN GLUCOSE PATHWAY | Insulin-mediated glucose transport |
| 0.1 | 0.8 | PID LIS1 PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
| 0.0 | 1.0 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 1.1 | PID AP1 PATHWAY | AP-1 transcription factor network |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 5.1 | 10.2 | REACTOME DNA STRAND ELONGATION | Genes involved in DNA strand elongation |
| 4.6 | 18.4 | REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Norepinephrine Neurotransmitter Release Cycle |
| 4.1 | 77.8 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 3.4 | 6.8 | REACTOME ACYL CHAIN REMODELLING OF PI | Genes involved in Acyl chain remodelling of PI |
| 3.2 | 106.0 | REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Glutamate Neurotransmitter Release Cycle |
| 3.2 | 6.3 | REACTOME PD1 SIGNALING | Genes involved in PD-1 signaling |
| 2.9 | 79.2 | REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
| 2.8 | 11.1 | REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
| 2.7 | 35.3 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 2.6 | 33.8 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |
| 2.5 | 65.9 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 2.4 | 48.7 | REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS | Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors) |
| 2.4 | 45.3 | REACTOME PLATELET CALCIUM HOMEOSTASIS | Genes involved in Platelet calcium homeostasis |
| 2.4 | 7.1 | REACTOME PLATELET AGGREGATION PLUG FORMATION | Genes involved in Platelet Aggregation (Plug Formation) |
| 2.3 | 55.6 | REACTOME INTRINSIC PATHWAY | Genes involved in Intrinsic Pathway |
| 2.3 | 61.8 | REACTOME PRE NOTCH PROCESSING IN GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 2.3 | 45.5 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 2.2 | 8.9 | REACTOME SHC MEDIATED SIGNALLING | Genes involved in SHC-mediated signalling |
| 2.1 | 34.1 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 2.1 | 48.3 | REACTOME ACYL CHAIN REMODELLING OF PE | Genes involved in Acyl chain remodelling of PE |
| 2.0 | 2.0 | REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
| 2.0 | 113.2 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |
| 1.9 | 33.0 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 1.9 | 29.0 | REACTOME SEMA4D IN SEMAPHORIN SIGNALING | Genes involved in Sema4D in semaphorin signaling |
| 1.8 | 9.2 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 1.7 | 7.0 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 1.7 | 13.3 | REACTOME PACKAGING OF TELOMERE ENDS | Genes involved in Packaging Of Telomere Ends |
| 1.6 | 55.8 | REACTOME G0 AND EARLY G1 | Genes involved in G0 and Early G1 |
| 1.6 | 35.2 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 1.5 | 64.7 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |
| 1.5 | 43.0 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 1.5 | 187.1 | REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES | Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides |
| 1.5 | 34.6 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 1.5 | 22.5 | REACTOME KERATAN SULFATE DEGRADATION | Genes involved in Keratan sulfate degradation |
| 1.5 | 31.5 | REACTOME INSULIN SYNTHESIS AND PROCESSING | Genes involved in Insulin Synthesis and Processing |
| 1.5 | 26.6 | REACTOME FGFR4 LIGAND BINDING AND ACTIVATION | Genes involved in FGFR4 ligand binding and activation |
| 1.5 | 49.4 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 1.5 | 53.7 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 1.4 | 25.3 | REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE | Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle |
| 1.4 | 27.5 | REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
| 1.3 | 9.4 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 1.3 | 46.8 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 1.3 | 64.9 | REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION | Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression |
| 1.3 | 60.5 | REACTOME ION CHANNEL TRANSPORT | Genes involved in Ion channel transport |
| 1.3 | 12.7 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 1.3 | 57.9 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 1.2 | 17.5 | REACTOME ROLE OF DCC IN REGULATING APOPTOSIS | Genes involved in Role of DCC in regulating apoptosis |
| 1.2 | 19.9 | REACTOME COMMON PATHWAY | Genes involved in Common Pathway |
| 1.2 | 29.8 | REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS | Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs) |
| 1.2 | 28.0 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 1.2 | 16.8 | REACTOME ANDROGEN BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
| 1.2 | 73.4 | REACTOME STRIATED MUSCLE CONTRACTION | Genes involved in Striated Muscle Contraction |
| 1.1 | 6.8 | REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 1.1 | 28.1 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 1.1 | 14.4 | REACTOME PROSTANOID LIGAND RECEPTORS | Genes involved in Prostanoid ligand receptors |
| 1.0 | 19.0 | REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
| 1.0 | 20.0 | REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT | Genes involved in ABC-family proteins mediated transport |
| 1.0 | 199.1 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 1.0 | 26.6 | REACTOME INSULIN RECEPTOR RECYCLING | Genes involved in Insulin receptor recycling |
| 1.0 | 3.9 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 1.0 | 5.9 | REACTOME PRE NOTCH EXPRESSION AND PROCESSING | Genes involved in Pre-NOTCH Expression and Processing |
| 0.9 | 12.7 | REACTOME SEROTONIN RECEPTORS | Genes involved in Serotonin receptors |
| 0.9 | 18.5 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.9 | 16.5 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.9 | 10.2 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |
| 0.8 | 24.6 | REACTOME EFFECTS OF PIP2 HYDROLYSIS | Genes involved in Effects of PIP2 hydrolysis |
| 0.8 | 6.5 | REACTOME ERK MAPK TARGETS | Genes involved in ERK/MAPK targets |
| 0.8 | 27.5 | REACTOME AMYLOIDS | Genes involved in Amyloids |
| 0.7 | 10.2 | REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR | Genes involved in Trafficking and processing of endosomal TLR |
| 0.7 | 4.3 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 | Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1) |
| 0.7 | 6.4 | REACTOME AMINE COMPOUND SLC TRANSPORTERS | Genes involved in Amine compound SLC transporters |
| 0.7 | 18.9 | REACTOME AMINE LIGAND BINDING RECEPTORS | Genes involved in Amine ligand-binding receptors |
| 0.7 | 41.8 | REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE | Genes involved in Cytochrome P450 - arranged by substrate type |
| 0.7 | 11.8 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.7 | 25.7 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.7 | 8.3 | REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE | Genes involved in Regulation of Insulin Secretion by Acetylcholine |
| 0.7 | 61.9 | REACTOME OLFACTORY SIGNALING PATHWAY | Genes involved in Olfactory Signaling Pathway |
| 0.7 | 8.9 | REACTOME REGULATION OF KIT SIGNALING | Genes involved in Regulation of KIT signaling |
| 0.7 | 15.0 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.7 | 9.3 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.6 | 12.2 | REACTOME P2Y RECEPTORS | Genes involved in P2Y receptors |
| 0.6 | 14.7 | REACTOME NEPHRIN INTERACTIONS | Genes involved in Nephrin interactions |
| 0.6 | 34.9 | REACTOME NRAGE SIGNALS DEATH THROUGH JNK | Genes involved in NRAGE signals death through JNK |
| 0.6 | 10.8 | REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING | Genes involved in Advanced glycosylation endproduct receptor signaling |
| 0.6 | 18.1 | REACTOME CD28 DEPENDENT PI3K AKT SIGNALING | Genes involved in CD28 dependent PI3K/Akt signaling |
| 0.6 | 14.2 | REACTOME CIRCADIAN CLOCK | Genes involved in Circadian Clock |
| 0.6 | 25.8 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.6 | 2.2 | REACTOME KERATAN SULFATE BIOSYNTHESIS | Genes involved in Keratan sulfate biosynthesis |
| 0.5 | 17.0 | REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
| 0.5 | 38.8 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.5 | 9.3 | REACTOME DEFENSINS | Genes involved in Defensins |
| 0.5 | 20.7 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.5 | 9.6 | REACTOME GAP JUNCTION ASSEMBLY | Genes involved in Gap junction assembly |
| 0.5 | 14.7 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.5 | 10.6 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.5 | 6.0 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.5 | 13.7 | REACTOME SIGNALING BY BMP | Genes involved in Signaling by BMP |
| 0.5 | 6.2 | REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX | Genes involved in Association of licensing factors with the pre-replicative complex |
| 0.5 | 6.6 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.5 | 14.4 | REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS | Genes involved in Sphingolipid de novo biosynthesis |
| 0.5 | 8.3 | REACTOME AMINE DERIVED HORMONES | Genes involved in Amine-derived hormones |
| 0.4 | 9.3 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.4 | 15.0 | REACTOME G PROTEIN ACTIVATION | Genes involved in G-protein activation |
| 0.4 | 7.4 | REACTOME HDL MEDIATED LIPID TRANSPORT | Genes involved in HDL-mediated lipid transport |
| 0.4 | 37.2 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.4 | 11.7 | REACTOME SIGNAL TRANSDUCTION BY L1 | Genes involved in Signal transduction by L1 |
| 0.4 | 7.2 | REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
| 0.4 | 8.7 | REACTOME REGULATION OF IFNA SIGNALING | Genes involved in Regulation of IFNA signaling |
| 0.4 | 2.7 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
| 0.4 | 69.4 | REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES | Genes involved in Transmission across Chemical Synapses |
| 0.4 | 3.7 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.4 | 10.4 | REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA | Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha |
| 0.4 | 30.9 | REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS | Genes involved in Class B/2 (Secretin family receptors) |
| 0.4 | 27.8 | REACTOME G ALPHA I SIGNALLING EVENTS | Genes involved in G alpha (i) signalling events |
| 0.4 | 5.5 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.3 | 8.0 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION | Genes involved in TRAF6 mediated IRF7 activation |
| 0.3 | 6.7 | REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.3 | 9.3 | REACTOME DOUBLE STRAND BREAK REPAIR | Genes involved in Double-Strand Break Repair |
| 0.3 | 22.4 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.3 | 6.6 | REACTOME BOTULINUM NEUROTOXICITY | Genes involved in Botulinum neurotoxicity |
| 0.3 | 6.4 | REACTOME IL 3 5 AND GM CSF SIGNALING | Genes involved in Interleukin-3, 5 and GM-CSF signaling |
| 0.3 | 6.6 | REACTOME POTASSIUM CHANNELS | Genes involved in Potassium Channels |
| 0.3 | 1.8 | REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN | Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen |
| 0.2 | 3.9 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.2 | 8.8 | REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.2 | 7.5 | REACTOME INTRINSIC PATHWAY FOR APOPTOSIS | Genes involved in Intrinsic Pathway for Apoptosis |
| 0.2 | 0.9 | REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING | Genes involved in Role of second messengers in netrin-1 signaling |
| 0.2 | 13.3 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.2 | 4.1 | REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE | Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase |
| 0.2 | 1.1 | REACTOME SHC MEDIATED CASCADE | Genes involved in SHC-mediated cascade |
| 0.2 | 0.8 | REACTOME DSCAM INTERACTIONS | Genes involved in DSCAM interactions |
| 0.1 | 4.9 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.1 | 4.0 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.1 | 2.1 | REACTOME INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.1 | 29.2 | REACTOME GENERIC TRANSCRIPTION PATHWAY | Genes involved in Generic Transcription Pathway |
| 0.1 | 1.2 | REACTOME VEGF LIGAND RECEPTOR INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.1 | 10.1 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.1 | 2.0 | REACTOME G ALPHA Q SIGNALLING EVENTS | Genes involved in G alpha (q) signalling events |
| 0.1 | 2.8 | REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.1 | 0.7 | REACTOME DCC MEDIATED ATTRACTIVE SIGNALING | Genes involved in DCC mediated attractive signaling |
| 0.1 | 1.1 | REACTOME SYNTHESIS OF PE | Genes involved in Synthesis of PE |
| 0.1 | 1.5 | REACTOME G ALPHA S SIGNALLING EVENTS | Genes involved in G alpha (s) signalling events |
| 0.1 | 2.9 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.0 | 0.5 | REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX | Genes involved in Degradation of the extracellular matrix |