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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for EGR1_EGR4

Z-value: 6.55

Motif logo

Transcription factors associated with EGR1_EGR4

Gene Symbol Gene ID Gene Info
ENSG00000120738.8 EGR1
ENSG00000135625.8 EGR4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EGR4hg38_v1_chr2_-_73293538_732937010.372.8e-08Click!
EGR1hg38_v1_chr5_+_138465472_1384654870.282.3e-05Click!

Activity profile of EGR1_EGR4 motif

Sorted Z-values of EGR1_EGR4 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EGR1_EGR4

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_+_197749855 27.67 ENST00000241502.9
forty-two-three domain containing 1
chr15_+_72118392 23.04 ENST00000340912.6
SUMO peptidase family member, NEDD8 specific
chr12_+_76764241 19.88 ENST00000550876.1
zinc finger DHHC-type palmitoyltransferase 17
chr11_-_64745331 18.54 ENST00000377489.5
ENST00000354024.7
RAS guanyl releasing protein 2
chr11_-_73142308 18.17 ENST00000409418.9
FCH and double SH3 domains 2
chr16_-_352714 15.92 ENST00000262320.8
axin 1
chr5_-_131796921 15.85 ENST00000307968.11
ENST00000307954.12
folliculin interacting protein 1
chr5_-_131797030 15.03 ENST00000615660.4
folliculin interacting protein 1
chr1_-_9129085 14.99 ENST00000377411.5
G protein-coupled receptor 157
chr7_-_44325490 14.31 ENST00000350811.7
calcium/calmodulin dependent protein kinase II beta
chr17_-_44324770 14.30 ENST00000592857.5
ENST00000586016.5
ENST00000590194.5
ENST00000588049.5
ENST00000586633.5
ENST00000377095.10
ENST00000537904.6
ENST00000585636.5
ENST00000585523.1
ENST00000225308.12
solute carrier family 25 member 39
chr19_-_49119092 13.88 ENST00000408991.4
chromosome 19 open reading frame 73
chr12_-_9115907 13.84 ENST00000318602.12
alpha-2-macroglobulin
chr16_+_83968244 13.10 ENST00000305202.9
N-terminal EF-hand calcium binding protein 2
chr12_+_76764109 12.75 ENST00000426126.7
zinc finger DHHC-type palmitoyltransferase 17
chr3_+_101849505 12.63 ENST00000326151.9
ENST00000326172.9
NFKB inhibitor zeta
chr19_-_36032799 12.51 ENST00000592017.5
ENST00000360535.9
CAP-Gly domain containing linker protein 3
chr11_-_64744811 12.49 ENST00000377497.7
ENST00000377487.5
ENST00000430645.1
RAS guanyl releasing protein 2
chr19_+_16324817 12.17 ENST00000248071.6
ENST00000592003.1
Kruppel like factor 2
chr19_+_18683656 12.14 ENST00000338797.10
ENST00000321949.13
CREB regulated transcription coactivator 1
chrX_+_55452119 11.89 ENST00000342972.3
MAGE family member H1
chr11_+_124739927 11.80 ENST00000284292.11
ENST00000412681.2
neurogranin
chr11_-_64744317 11.54 ENST00000419843.1
ENST00000394430.5
RAS guanyl releasing protein 2
chr7_-_44325421 11.10 ENST00000395747.6
ENST00000347193.8
ENST00000346990.8
ENST00000258682.10
ENST00000353625.8
ENST00000421607.1
ENST00000424197.5
calcium/calmodulin dependent protein kinase II beta
chr16_-_2135898 10.93 ENST00000262304.9
ENST00000423118.5
polycystin 1, transient receptor potential channel interacting
chr19_+_49119531 10.91 ENST00000334186.9
PTPRF interacting protein alpha 3
chr14_+_75428011 10.83 ENST00000651602.1
ENST00000559060.5
Jun dimerization protein 2
chr17_-_7916280 10.61 ENST00000324348.9
ring finger protein 227
chr20_-_49484258 10.43 ENST00000635465.1
potassium voltage-gated channel subfamily B member 1
chr15_-_72118114 10.40 ENST00000356056.10
ENST00000569314.1
myosin IXA
chrX_-_47619850 10.39 ENST00000295987.13
ENST00000340666.5
synapsin I
chr4_-_36244438 10.12 ENST00000303965.9
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_-_7915929 10.11 ENST00000635932.1
ENST00000640240.1
ring finger protein 227
chr11_-_64744993 9.95 ENST00000377485.5
RAS guanyl releasing protein 2
chr12_+_78864768 9.94 ENST00000261205.9
ENST00000457153.6
synaptotagmin 1
chrX_-_51496572 9.87 ENST00000375992.4
nudix hydrolase 11
chr11_+_3855629 9.60 ENST00000526596.2
ENST00000300737.8
ENST00000616714.4
stromal interaction molecule 1
chr5_-_131796965 9.59 ENST00000514667.1
ENST00000511848.1
ENST00000510461.6
novel protein
folliculin interacting protein 1
chr5_+_68288346 9.35 ENST00000320694.12
phosphoinositide-3-kinase regulatory subunit 1
chr11_-_64844620 9.31 ENST00000342711.6
CDC42 binding protein kinase gamma
chr17_-_76240289 9.31 ENST00000647930.1
ENST00000592271.1
ENST00000319945.10
ring finger protein 157
chr15_+_83447328 9.20 ENST00000427482.7
SH3 domain containing GRB2 like 3, endophilin A3
chr10_+_48306639 9.16 ENST00000395611.7
ENST00000432379.5
ENST00000374189.5
mitogen-activated protein kinase 8
chr15_+_83447411 9.10 ENST00000324537.5
SH3 domain containing GRB2 like 3, endophilin A3
chr1_+_9539431 9.01 ENST00000302692.7
solute carrier family 25 member 33
chr3_+_39051990 8.88 ENST00000302313.10
WD repeat domain 48
chr9_+_17579059 8.77 ENST00000380607.5
SH3 domain containing GRB2 like 2, endophilin A1
chr14_+_99684283 8.71 ENST00000261835.8
cytochrome P450 family 46 subfamily A member 1
chr5_+_177426701 8.54 ENST00000507633.5
ENST00000393576.7
ENST00000355958.9
ENST00000528793.5
ENST00000512684.1
G protein-coupled receptor kinase 6
chr9_-_127980976 8.47 ENST00000373095.6
family with sequence similarity 102 member A
chr22_+_28742024 8.46 ENST00000216027.8
ENST00000398941.6
HscB mitochondrial iron-sulfur cluster cochaperone
chr5_+_173056345 8.43 ENST00000522692.5
ENST00000296953.6
ENST00000520420.5
CREB3 regulatory factor
chr2_+_218568809 8.43 ENST00000273064.11
CCR4-NOT transcription complex subunit 9
chr21_+_46458846 8.38 ENST00000417564.3
ENST00000651436.1
ENST00000400274.5
ENST00000457905.7
ENST00000466639.5
ENST00000435722.7
disco interacting protein 2 homolog A
chr16_+_28822982 8.34 ENST00000336783.9
ENST00000340394.12
ENST00000325215.10
ENST00000382686.8
ENST00000395547.6
ENST00000564304.5
ataxin 2 like
chr2_-_222656067 8.30 ENST00000281828.8
phenylalanyl-tRNA synthetase subunit beta
chr20_-_4015518 8.26 ENST00000545616.2
ENST00000358395.11
ring finger protein 24
chr17_+_79778135 8.23 ENST00000310942.9
ENST00000269399.5
chromobox 2
chr4_-_81471855 8.19 ENST00000436139.6
ENST00000613784.1
RasGEF domain family member 1B
chr1_-_200669708 8.15 ENST00000436897.1
ENST00000447706.6
ENST00000331314.11
DEAD-box helicase 59
chr21_+_6499203 8.12 ENST00000619537.5
crystallin alpha A2
chr15_+_31326807 8.12 ENST00000307145.4
Kruppel like factor 13
chr22_+_41381923 8.10 ENST00000266304.9
TEF transcription factor, PAR bZIP family member
chr15_-_64356047 8.09 ENST00000634654.1
casein kinase 1 gamma 1
chr11_+_95789965 8.09 ENST00000537677.5
centrosomal protein 57
chr19_+_33621944 7.94 ENST00000650847.1
ENST00000591231.5
ENST00000434302.5
ENST00000438847.7
carbohydrate sulfotransferase 8
chr7_-_100428657 7.86 ENST00000360951.8
ENST00000398027.6
ENST00000684423.1
ENST00000472716.1
zinc finger CW-type and PWWP domain containing 1
chr3_-_57693045 7.82 ENST00000311128.10
DENN domain containing 6A
chr19_-_42242526 7.69 ENST00000222330.8
ENST00000676537.1
glycogen synthase kinase 3 alpha
chr16_-_2214776 7.66 ENST00000333503.8
phosphoglycolate phosphatase
chr1_-_23484171 7.56 ENST00000336689.8
ENST00000437606.6
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr17_-_76240478 7.56 ENST00000269391.11
ring finger protein 157
chr8_-_126558461 7.51 ENST00000304916.4
LRAT domain containing 2
chr11_-_113875555 7.46 ENST00000003302.8
ENST00000545540.5
ubiquitin specific peptidase 28
chr7_-_40134610 7.46 ENST00000306984.8
M-phase specific PLK1 interacting protein
chr17_+_49788672 7.44 ENST00000454930.6
ENST00000259021.9
ENST00000509773.5
ENST00000510819.5
ENST00000424009.6
lysine acetyltransferase 7
chr5_-_131635030 7.43 ENST00000308008.10
ENST00000296859.10
ENST00000627212.2
ENST00000507093.5
ENST00000509018.6
ENST00000510071.5
Rap guanine nucleotide exchange factor 6
chr5_+_177426667 7.40 ENST00000355472.10
G protein-coupled receptor kinase 6
chr5_-_178627001 7.32 ENST00000611575.4
ENST00000520957.1
ENST00000316308.9
ENST00000611733.4
CDC like kinase 4
chr21_+_5022493 7.31 ENST00000612610.4
ENST00000620481.4
ENST00000623960.4
ENST00000623795.1
novel protein, similar to inducible T-cell co-stimulator ligand ICOSLG
chr19_-_5622768 7.24 ENST00000252542.9
scaffold attachment factor B2
chr19_+_4969105 7.19 ENST00000611640.4
ENST00000159111.9
ENST00000588337.5
ENST00000381759.8
lysine demethylase 4B
chr7_+_107044689 7.17 ENST00000265717.5
protein kinase cAMP-dependent type II regulatory subunit beta
chr5_+_138465472 7.12 ENST00000239938.5
early growth response 1
chr11_+_92224801 7.08 ENST00000525166.6
FAT atypical cadherin 3
chr14_+_100726883 7.07 ENST00000341267.9
ENST00000331224.10
ENST00000556051.1
delta like non-canonical Notch ligand 1
chr15_-_64356074 7.06 ENST00000634811.1
ENST00000303052.13
ENST00000607537.6
casein kinase 1 gamma 1
chr14_-_53153098 7.04 ENST00000612692.4
ENST00000395606.5
DDHD domain containing 1
chr12_+_130337872 7.04 ENST00000245255.7
piwi like RNA-mediated gene silencing 1
chr22_-_50582785 7.03 ENST00000406938.3
choline kinase beta
chr15_-_72117712 7.00 ENST00000444904.5
ENST00000564571.5
myosin IXA
chr10_+_48306698 6.98 ENST00000374179.8
mitogen-activated protein kinase 8
chr2_+_218568558 6.89 ENST00000627282.2
ENST00000542068.5
CCR4-NOT transcription complex subunit 9
chr9_+_34958254 6.87 ENST00000242315.3
PHD finger protein 24
chr19_+_1524068 6.82 ENST00000642079.2
ENST00000454744.7
ENST00000588430.3
polo like kinase 5 (inactive)
chr3_-_126475863 6.81 ENST00000336332.5
ENST00000389709.8
ZXD family zinc finger C
chr16_+_50742059 6.80 ENST00000311559.13
ENST00000564326.5
ENST00000566206.5
ENST00000427738.8
CYLD lysine 63 deubiquitinase
chr1_-_15976070 6.72 ENST00000537142.5
ENST00000375743.9
zinc finger and BTB domain containing 17
chr11_-_22829793 6.68 ENST00000354193.5
small VCP interacting protein
chr16_+_30183595 6.68 ENST00000219150.10
ENST00000570045.5
ENST00000565497.5
ENST00000570244.5
coronin 1A
chr1_-_15524183 6.66 ENST00000333868.10
ENST00000440484.1
caspase 9
chr17_-_8162932 6.62 ENST00000488857.5
ENST00000316509.11
ENST00000481878.1
ENST00000498285.1
vesicle associated membrane protein 2
novel protein
chr2_-_144332466 6.62 ENST00000682281.1
ENST00000463875.6
ENST00000542155.5
glycosyltransferase like domain containing 1
chr10_+_27155339 6.59 ENST00000375940.9
ENST00000342386.10
microtubule associated serine/threonine kinase like
chr16_+_58463663 6.57 ENST00000258187.9
NDRG family member 4
chr12_+_70366277 6.56 ENST00000258111.5
potassium calcium-activated channel subfamily M regulatory beta subunit 4
chr11_+_119206298 6.56 ENST00000634586.1
ENST00000634840.1
ENST00000264033.6
ENST00000637974.1
Cbl proto-oncogene
chr5_-_141618914 6.52 ENST00000518047.5
diaphanous related formin 1
chr19_-_3801791 6.50 ENST00000590849.1
ENST00000395045.6
megakaryocyte-associated tyrosine kinase
chr11_-_123654581 6.48 ENST00000392770.6
ENST00000530277.5
ENST00000299333.8
sodium voltage-gated channel beta subunit 3
chr13_-_45341086 6.47 ENST00000309246.9
ENST00000379060.8
ENST00000379055.5
ENST00000527226.2
ENST00000530705.6
ENST00000379056.5
ENST00000616577.4
tumor protein, translationally-controlled 1
chr13_-_36920227 6.43 ENST00000379826.5
ENST00000350148.10
SMAD family member 9
chr4_+_153466324 6.40 ENST00000409663.7
ENST00000409959.8
transmembrane 131 like
chr1_+_5992639 6.37 ENST00000666163.1
ENST00000671676.1
ENST00000658883.1
ENST00000445501.6
ENST00000668706.1
ENST00000653262.1
ENST00000389632.9
ENST00000341524.6
ENST00000462676.3
potassium voltage-gated channel subfamily A regulatory beta subunit 2
chr7_+_100177743 6.36 ENST00000394018.6
ENST00000416412.5
stromal antigen 3
chr14_-_21025490 6.35 ENST00000553442.5
ENST00000555869.5
ENST00000556457.5
ENST00000397844.6
ENST00000554415.5
ENST00000556974.5
ENST00000554419.5
ENST00000298687.9
ENST00000397858.5
ENST00000360463.7
ENST00000350792.7
ENST00000397847.6
NDRG family member 2
chr16_+_50742037 6.33 ENST00000569418.5
CYLD lysine 63 deubiquitinase
chr7_+_100177897 6.27 ENST00000317296.9
ENST00000615138.5
ENST00000620100.5
ENST00000422690.5
ENST00000439782.1
stromal antigen 3
chr7_-_44325653 6.26 ENST00000440254.6
calcium/calmodulin dependent protein kinase II beta
chr22_+_19714450 6.25 ENST00000455784.7
ENST00000406395.5
septin 5
chr14_-_53153281 6.24 ENST00000357758.3
ENST00000673822.2
DDHD domain containing 1
chr19_-_36379185 6.18 ENST00000270001.12
ZFP14 zinc finger protein
chr16_+_50742110 6.17 ENST00000566679.6
ENST00000564634.5
ENST00000398568.6
CYLD lysine 63 deubiquitinase
chr19_+_42220283 6.15 ENST00000301215.8
ENST00000597945.1
zinc finger protein 526
chr1_-_160031946 6.11 ENST00000368090.5
phosphatidylinositol glycan anchor biosynthesis class M
chr11_-_46391767 6.10 ENST00000682254.1
cholinergic receptor muscarinic 4
chr1_+_32539418 6.08 ENST00000373510.9
ENST00000316459.4
zinc finger and BTB domain containing 8A
chr16_+_1153098 6.03 ENST00000348261.11
calcium voltage-gated channel subunit alpha1 H
chr19_-_12484773 6.01 ENST00000397732.8
zinc finger protein 709
chr13_-_40666600 5.99 ENST00000379561.6
forkhead box O1
chr10_+_38010617 5.95 ENST00000307441.13
ENST00000374618.7
ENST00000628825.2
ENST00000458705.6
ENST00000432900.7
ENST00000469037.2
zinc finger protein 33A
chr20_-_4015389 5.93 ENST00000336095.10
ring finger protein 24
chr10_+_119818699 5.90 ENST00000650409.1
inositol polyphosphate-5-phosphatase F
chr15_-_65133780 5.81 ENST00000204549.9
programmed cell death 7
chr5_-_88883701 5.78 ENST00000636998.1
myocyte enhancer factor 2C
chr16_+_1333631 5.78 ENST00000397488.6
ENST00000562208.5
ENST00000568887.5
ENST00000426824.8
BAI1 associated protein 3
chr19_+_47256518 5.77 ENST00000643617.1
ENST00000221922.11
coiled-coil domain containing 9
chr1_-_24930263 5.76 ENST00000308873.11
RUNX family transcription factor 3
chr14_-_100587404 5.75 ENST00000554140.2
brain enriched guanylate kinase associated
chr2_-_25341886 5.74 ENST00000321117.10
DNA methyltransferase 3 alpha
chr19_+_39406831 5.73 ENST00000597629.3
ENST00000594442.2
ENST00000594045.2
ZFP36 ring finger protein
chrX_-_49200174 5.69 ENST00000472598.5
ENST00000263233.9
ENST00000479808.5
synaptophysin
chr9_+_121074944 5.69 ENST00000373855.7
centriolin
chr15_-_77420135 5.69 ENST00000560626.6
pseudopodium enriched atypical kinase 1
chr22_-_39152622 5.67 ENST00000216133.10
chromobox 7
chr1_-_33182030 5.65 ENST00000291416.10
tripartite motif containing 62
chr11_-_65780917 5.64 ENST00000532090.3
adaptor related protein complex 5 subunit beta 1
chr9_+_19230680 5.54 ENST00000434457.7
DENN domain containing 4C
chr14_+_101561351 5.53 ENST00000510508.4
iodothyronine deiodinase 3
chr19_+_36605292 5.52 ENST00000460670.5
ENST00000292928.7
ENST00000439428.5
zinc finger protein 382
chr1_-_15524344 5.51 ENST00000348549.9
ENST00000546424.5
caspase 9
chr7_-_712437 5.49 ENST00000360274.8
protein kinase cAMP-dependent type I regulatory subunit beta
chr5_-_88883147 5.46 ENST00000513252.5
ENST00000506554.5
ENST00000508569.5
ENST00000637732.1
ENST00000504921.7
ENST00000637481.1
ENST00000510942.5
myocyte enhancer factor 2C
chr6_-_137219340 5.46 ENST00000367739.9
ENST00000458076.5
ENST00000414770.5
interferon gamma receptor 1
chr10_+_132332136 5.42 ENST00000344079.9
ENST00000625755.2
ENST00000368614.8
leucine rich repeat containing 27
chr1_+_162069674 5.38 ENST00000361897.10
nitric oxide synthase 1 adaptor protein
chr9_-_76906090 5.35 ENST00000376718.8
prune homolog 2 with BCH domain
chr6_-_111873421 5.31 ENST00000368678.8
ENST00000523238.5
ENST00000354650.7
FYN proto-oncogene, Src family tyrosine kinase
chr10_-_27155214 5.28 ENST00000477432.1
YME1 like 1 ATPase
chr6_+_137867241 5.22 ENST00000612899.5
ENST00000420009.5
TNF alpha induced protein 3
chr15_+_90903288 5.22 ENST00000559717.6
mannosidase alpha class 2A member 2
chr15_+_32641665 5.18 ENST00000300175.8
ENST00000413748.6
ENST00000494364.5
ENST00000497208.5
secretogranin V
chr15_-_77420087 5.18 ENST00000564328.5
ENST00000682557.1
ENST00000558305.5
pseudopodium enriched atypical kinase 1
chr2_+_60881553 5.17 ENST00000394479.4
REL proto-oncogene, NF-kB subunit
chr17_-_42745025 5.17 ENST00000592492.5
ENST00000585893.5
ENST00000593214.5
ENST00000590078.5
ENST00000428826.7
ENST00000586382.5
ENST00000415827.6
ENST00000592743.5
ENST00000586089.5
enhancer of zeste 1 polycomb repressive complex 2 subunit
chr20_+_49812697 5.15 ENST00000417961.5
solute carrier family 9 member A8
chr2_+_950836 5.15 ENST00000308624.10
ENST00000407292.1
syntrophin gamma 2
chr5_+_109689915 5.09 ENST00000261483.5
mannosidase alpha class 2A member 1
chr1_+_6785437 5.07 ENST00000303635.12
ENST00000473578.5
ENST00000557126.5
calmodulin binding transcription activator 1
chr11_-_64744102 5.04 ENST00000431822.5
ENST00000394432.8
ENST00000377486.7
RAS guanyl releasing protein 2
chr19_-_40690629 5.02 ENST00000252891.8
NUMB like endocytic adaptor protein
chr2_-_27495185 5.01 ENST00000264703.4
fibronectin type III domain containing 4
chrX_-_53321319 4.99 ENST00000640694.1
ENST00000674510.1
ENST00000675719.1
ENST00000642864.1
IQ motif and Sec7 domain ArfGEF 2
chr6_-_32128191 4.99 ENST00000453203.2
ENST00000375203.8
ENST00000375201.8
activating transcription factor 6 beta
chrX_-_18984090 4.98 ENST00000379942.5
phosphorylase kinase regulatory subunit alpha 2
chr19_+_7920976 4.96 ENST00000597584.5
small nuclear RNA activating complex polypeptide 2
chr1_+_151070740 4.94 ENST00000368918.8
GA binding protein transcription factor subunit beta 2
chr10_+_122461545 4.92 ENST00000368984.8
HtrA serine peptidase 1
chr19_-_51065067 4.92 ENST00000595547.5
ENST00000335422.3
ENST00000595793.6
ENST00000596955.1
kallikrein related peptidase 13
chr19_-_56477308 4.90 ENST00000504904.8
ENST00000292069.10
zinc finger protein 667
chr16_-_970847 4.89 ENST00000568897.5
lipase maturation factor 1
chr13_+_30617902 4.85 ENST00000255304.9
ENST00000614860.1
ubiquitin specific peptidase like 1
chr20_+_17227020 4.85 ENST00000262545.7
ENST00000536609.1
proprotein convertase subtilisin/kexin type 2
chr11_-_2139382 4.83 ENST00000416167.7
insulin like growth factor 2
chr19_+_53869384 4.82 ENST00000391769.2
myeloid associated differentiation marker
chr4_-_82430192 4.82 ENST00000621267.4
ENST00000614627.4
heterogeneous nuclear ribonucleoprotein D like
chr14_-_52791597 4.81 ENST00000216410.8
ENST00000557604.1
glucosamine-phosphate N-acetyltransferase 1
chr1_+_161524539 4.80 ENST00000309758.6
heat shock protein family A (Hsp70) member 6
chr2_-_225042433 4.80 ENST00000258390.12
dedicator of cytokinesis 10
chr22_+_29073112 4.76 ENST00000327813.9
ENST00000407188.5
kringle containing transmembrane protein 1
chr2_-_191150971 4.75 ENST00000409995.5
ENST00000392320.7
signal transducer and activator of transcription 4
chr20_-_62937936 4.73 ENST00000266070.8
ENST00000370371.8
death inducer-obliterator 1
chr8_-_98294195 4.72 ENST00000430223.7
NIPA like domain containing 2
chr16_+_2537997 4.71 ENST00000441549.7
ENST00000268673.11
ENST00000342085.9
ENST00000389224.7
3-phosphoinositide dependent protein kinase 1
chr1_-_92486049 4.69 ENST00000427103.5
growth factor independent 1 transcriptional repressor
chr19_+_16888991 4.69 ENST00000248076.4
F2R like thrombin or trypsin receptor 3
chr22_-_20117177 4.69 ENST00000439169.2
ENST00000252136.12
ENST00000445045.1
ENST00000404751.7
ENST00000403707.7
tRNA methyltransferase 2 homolog A
chr19_-_45768627 4.68 ENST00000560160.1
SIX homeobox 5
chr2_+_62196107 4.67 ENST00000301998.5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
chr14_+_100065400 4.66 ENST00000555706.5
ENST00000392920.8
ENST00000555048.5
Enah/Vasp-like

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.1 40.5 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
6.4 19.3 GO:1990108 protein linear deubiquitination(GO:1990108)
5.4 16.1 GO:1902595 regulation of DNA replication origin binding(GO:1902595)
5.3 15.9 GO:0048319 axial mesoderm morphogenesis(GO:0048319)
4.6 27.9 GO:0016926 protein desumoylation(GO:0016926)
4.6 13.8 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
4.0 12.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
3.9 15.7 GO:0071409 cellular response to cycloheximide(GO:0071409)
3.3 9.9 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
3.3 13.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020) negative regulation of G-protein coupled receptor internalization(GO:1904021)
3.2 9.7 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
3.1 12.5 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
3.1 9.3 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
3.0 9.0 GO:1904897 regulation of hepatic stellate cell proliferation(GO:1904897) positive regulation of hepatic stellate cell proliferation(GO:1904899) hepatic stellate cell proliferation(GO:1990922)
3.0 9.0 GO:0006864 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
2.9 8.8 GO:0097477 spinal cord motor neuron migration(GO:0097476) lateral motor column neuron migration(GO:0097477)
2.9 8.6 GO:0099557 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission(GO:0099557)
2.7 10.9 GO:0072237 metanephric proximal tubule development(GO:0072237)
2.7 10.8 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
2.5 7.4 GO:0072716 response to actinomycin D(GO:0072716)
2.5 41.8 GO:1903830 magnesium ion transmembrane transport(GO:1903830)
2.4 2.4 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
2.4 9.6 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
2.3 2.3 GO:1902303 negative regulation of potassium ion export(GO:1902303)
2.2 9.0 GO:1903116 positive regulation of actin filament-based movement(GO:1903116) positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
2.2 6.6 GO:0008355 olfactory learning(GO:0008355)
2.2 44.0 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
2.2 17.3 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
2.1 8.4 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
2.0 8.2 GO:0036369 transcription factor catabolic process(GO:0036369)
2.0 2.0 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
2.0 9.9 GO:1901907 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
1.9 5.8 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
1.9 7.7 GO:0006258 UDP-glucose catabolic process(GO:0006258) positive regulation of adrenergic receptor signaling pathway(GO:0071879) negative regulation of type B pancreatic cell development(GO:2000077)
1.9 5.7 GO:1904580 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
1.8 8.8 GO:0006041 glucosamine metabolic process(GO:0006041)
1.7 6.8 GO:0014859 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
1.7 6.8 GO:0002357 defense response to tumor cell(GO:0002357)
1.7 6.7 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
1.7 6.7 GO:0052552 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
1.7 8.3 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
1.6 9.8 GO:0061092 involuntary skeletal muscle contraction(GO:0003011) regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
1.6 4.8 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
1.6 8.0 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
1.6 4.7 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
1.6 6.3 GO:0051697 protein delipidation(GO:0051697)
1.5 6.0 GO:2000327 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
1.5 6.0 GO:1902617 response to fluoride(GO:1902617)
1.5 10.4 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
1.5 5.9 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
1.4 2.9 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
1.4 8.5 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
1.4 4.2 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
1.4 4.2 GO:0021718 pons maturation(GO:0021586) superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
1.4 2.8 GO:0060024 rhythmic synaptic transmission(GO:0060024)
1.4 4.2 GO:0045643 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
1.4 16.6 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
1.4 6.8 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
1.3 13.4 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
1.3 1.3 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
1.3 15.7 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
1.3 3.9 GO:0060903 positive regulation of meiosis I(GO:0060903)
1.3 3.8 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
1.2 15.9 GO:0043320 natural killer cell degranulation(GO:0043320)
1.2 3.6 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
1.2 4.8 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
1.2 7.2 GO:0097338 response to clozapine(GO:0097338)
1.2 7.0 GO:0034587 piRNA metabolic process(GO:0034587)
1.2 9.2 GO:0006013 mannose metabolic process(GO:0006013)
1.2 3.5 GO:0071494 cellular response to UV-C(GO:0071494)
1.1 6.9 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
1.1 3.4 GO:0048073 regulation of eye pigmentation(GO:0048073)
1.1 10.1 GO:0042670 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
1.1 6.7 GO:0051585 negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
1.1 3.3 GO:0098528 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
1.1 4.4 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
1.1 18.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
1.1 4.3 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
1.0 3.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
1.0 8.0 GO:0000160 phosphorelay signal transduction system(GO:0000160)
1.0 13.0 GO:0035372 protein localization to microtubule(GO:0035372)
1.0 3.0 GO:0003358 noradrenergic neuron development(GO:0003358)
1.0 4.9 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
1.0 2.9 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
1.0 7.8 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
1.0 14.6 GO:0051531 NFAT protein import into nucleus(GO:0051531)
1.0 4.8 GO:0030070 insulin processing(GO:0030070)
1.0 8.6 GO:0033578 protein glycosylation in Golgi(GO:0033578)
1.0 5.7 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.9 3.8 GO:0002317 plasma cell differentiation(GO:0002317)
0.9 15.0 GO:0032025 response to cobalt ion(GO:0032025)
0.9 3.7 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.9 4.7 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.9 2.8 GO:1905064 negative regulation of vascular smooth muscle cell differentiation(GO:1905064)
0.9 14.5 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.9 8.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.9 2.7 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.9 9.0 GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.9 3.6 GO:0070434 positive regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070426) positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070434)
0.9 4.4 GO:0072366 regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.9 3.5 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.9 2.6 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.9 4.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.9 4.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.8 3.4 GO:0072103 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.8 2.5 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.8 3.3 GO:1990834 negative regulation of T-helper 1 cell differentiation(GO:0045626) response to odorant(GO:1990834)
0.8 1.6 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.8 2.4 GO:0098582 innate vocalization behavior(GO:0098582)
0.8 2.4 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.8 9.8 GO:0060019 radial glial cell differentiation(GO:0060019)
0.8 4.8 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.8 6.4 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.8 6.4 GO:0070995 NADPH oxidation(GO:0070995)
0.8 3.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.8 8.7 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.8 10.9 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.8 0.8 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.8 10.8 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.8 3.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.8 4.5 GO:0034128 negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
0.7 12.6 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.7 6.6 GO:0007135 meiosis II(GO:0007135)
0.7 7.3 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.7 2.2 GO:0019046 release from viral latency(GO:0019046)
0.7 2.1 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.7 1.4 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.7 1.3 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.7 13.9 GO:0034199 activation of protein kinase A activity(GO:0034199)
0.7 1.3 GO:0002537 nitric oxide production involved in inflammatory response(GO:0002537)
0.7 5.9 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.6 5.8 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.6 5.8 GO:0035865 cellular response to potassium ion(GO:0035865)
0.6 1.9 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.6 2.6 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.6 7.0 GO:0006657 CDP-choline pathway(GO:0006657)
0.6 56.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.6 11.4 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.6 1.9 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.6 5.0 GO:0021873 forebrain neuroblast division(GO:0021873)
0.6 3.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.6 1.9 GO:0006172 ADP biosynthetic process(GO:0006172) purine deoxyribonucleoside diphosphate biosynthetic process(GO:0009183)
0.6 3.1 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.6 4.8 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.6 1.8 GO:0001757 somite specification(GO:0001757)
0.6 8.5 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.6 0.6 GO:0061056 sclerotome development(GO:0061056)
0.6 6.6 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.6 4.8 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.6 4.7 GO:0060155 platelet dense granule organization(GO:0060155)
0.6 4.6 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.6 3.4 GO:0035063 nuclear speck organization(GO:0035063)
0.6 4.6 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.6 6.8 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.6 2.3 GO:0071110 protein biotinylation(GO:0009305) histone biotinylation(GO:0071110)
0.6 1.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.6 8.4 GO:0010918 positive regulation of mitochondrial membrane potential(GO:0010918)
0.5 3.3 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.5 1.6 GO:0098935 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.5 5.4 GO:0043589 skin morphogenesis(GO:0043589)
0.5 1.6 GO:2001033 oncogene-induced cell senescence(GO:0090402) negative regulation of double-strand break repair via nonhomologous end joining(GO:2001033)
0.5 1.6 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.5 2.1 GO:0044026 DNA hypermethylation(GO:0044026)
0.5 4.7 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.5 5.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.5 1.0 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.5 1.5 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.5 4.6 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.5 7.2 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.5 2.6 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.5 6.6 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.5 2.0 GO:0010868 negative regulation of triglyceride biosynthetic process(GO:0010868) regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.5 11.0 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.5 3.4 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.5 2.4 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.5 1.5 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.5 8.7 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.5 1.9 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.5 2.9 GO:0050893 sensory processing(GO:0050893)
0.5 1.4 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.5 1.4 GO:0042412 taurine biosynthetic process(GO:0042412)
0.4 2.6 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.4 1.3 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.4 1.3 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.4 1.7 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.4 1.3 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.4 0.8 GO:0060061 Spemann organizer formation(GO:0060061)
0.4 2.1 GO:0034334 adherens junction maintenance(GO:0034334)
0.4 4.2 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.4 11.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.4 1.2 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.4 17.9 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.4 3.6 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.4 4.0 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.4 2.4 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.4 14.4 GO:0006783 heme biosynthetic process(GO:0006783)
0.4 4.8 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.4 0.8 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.4 18.8 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.4 7.7 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.4 1.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.4 2.7 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.4 1.9 GO:0006741 NADP biosynthetic process(GO:0006741)
0.4 6.4 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.4 4.8 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.4 2.6 GO:0016322 neuron remodeling(GO:0016322)
0.4 2.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.4 4.0 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702)
0.4 3.7 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.4 6.5 GO:0005513 detection of calcium ion(GO:0005513)
0.4 2.5 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.4 3.9 GO:0001573 ganglioside metabolic process(GO:0001573)
0.4 1.8 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.4 1.1 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.4 2.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.4 4.6 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.3 1.7 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.3 2.1 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.3 8.6 GO:0060008 Sertoli cell differentiation(GO:0060008)
0.3 7.7 GO:0034453 microtubule anchoring(GO:0034453)
0.3 1.3 GO:0035900 response to isolation stress(GO:0035900)
0.3 2.3 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.3 2.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.3 3.3 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.3 2.3 GO:0080009 mRNA methylation(GO:0080009)
0.3 2.9 GO:0070444 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.3 2.2 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.3 3.7 GO:0048681 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.3 2.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.3 3.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.3 1.2 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.3 1.2 GO:0003431 growth plate cartilage chondrocyte growth(GO:0003430) growth plate cartilage chondrocyte development(GO:0003431) trachea cartilage development(GO:0060534) Harderian gland development(GO:0070384)
0.3 4.5 GO:0035988 chondrocyte proliferation(GO:0035988)
0.3 1.2 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.3 1.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.3 2.4 GO:0060766 negative regulation of androgen receptor signaling pathway(GO:0060766)
0.3 1.2 GO:1903182 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
0.3 8.8 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.3 1.4 GO:0072553 terminal button organization(GO:0072553)
0.3 8.3 GO:0090312 positive regulation of protein deacetylation(GO:0090312)
0.3 4.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.3 1.4 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.3 7.2 GO:0009299 mRNA transcription(GO:0009299)
0.3 4.6 GO:0006020 inositol metabolic process(GO:0006020)
0.3 2.4 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.3 7.8 GO:0007398 ectoderm development(GO:0007398)
0.3 1.3 GO:1905245 regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902959) positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) regulation of aspartic-type peptidase activity(GO:1905245) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.3 2.1 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.3 1.8 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.3 2.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.3 4.6 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.3 6.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.3 3.3 GO:0060081 membrane hyperpolarization(GO:0060081)
0.2 1.5 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.2 1.5 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.2 1.0 GO:0072301 metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262) regulation of metanephric glomerular mesangial cell proliferation(GO:0072301)
0.2 1.9 GO:0035524 proline transmembrane transport(GO:0035524)
0.2 4.6 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.2 3.2 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.2 0.7 GO:0061011 gall bladder development(GO:0061010) hepatic duct development(GO:0061011)
0.2 7.1 GO:0010719 negative regulation of epithelial to mesenchymal transition(GO:0010719)
0.2 2.1 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.2 2.1 GO:0015871 choline transport(GO:0015871)
0.2 1.9 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 2.3 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.2 1.9 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 2.8 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.2 1.2 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.2 4.6 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.2 5.7 GO:0031167 rRNA methylation(GO:0031167)
0.2 2.5 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.2 1.8 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 2.7 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.2 0.9 GO:0015870 acetylcholine transport(GO:0015870)
0.2 4.8 GO:0007413 axonal fasciculation(GO:0007413)
0.2 0.7 GO:1901874 negative regulation of post-translational protein modification(GO:1901874)
0.2 4.7 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.2 1.9 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.2 1.3 GO:0007296 vitellogenesis(GO:0007296)
0.2 0.6 GO:0006478 peptidyl-tyrosine sulfation(GO:0006478)
0.2 1.4 GO:0032960 regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.2 1.6 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.2 1.2 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.2 1.6 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.2 1.2 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.2 3.6 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.2 2.0 GO:0006491 N-glycan processing(GO:0006491)
0.2 0.8 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.2 0.6 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.2 12.4 GO:0071364 cellular response to epidermal growth factor stimulus(GO:0071364)
0.2 3.5 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.2 1.5 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.2 2.8 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.2 1.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 2.2 GO:0036010 protein localization to endosome(GO:0036010)
0.2 2.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 2.0 GO:0044030 regulation of DNA methylation(GO:0044030)
0.2 1.6 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.2 0.9 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.2 2.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.2 3.6 GO:0006895 Golgi to endosome transport(GO:0006895)
0.2 1.6 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.2 3.5 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.2 1.0 GO:0060482 bronchus development(GO:0060433) lobar bronchus epithelium development(GO:0060481) lobar bronchus development(GO:0060482)
0.2 1.5 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.2 4.0 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.2 0.8 GO:0009450 gamma-aminobutyric acid catabolic process(GO:0009450)
0.2 0.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.2 1.8 GO:0097106 postsynaptic density organization(GO:0097106) postsynaptic density assembly(GO:0097107) gephyrin clustering involved in postsynaptic density assembly(GO:0097116) neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.2 1.1 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.2 1.3 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 1.1 GO:0051024 positive regulation of immunoglobulin secretion(GO:0051024)
0.2 7.6 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.2 2.0 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.2 2.8 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.2 10.7 GO:0008306 associative learning(GO:0008306)
0.2 1.7 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.2 1.6 GO:0060068 vagina development(GO:0060068)
0.2 5.4 GO:0090022 regulation of neutrophil chemotaxis(GO:0090022)
0.2 2.9 GO:0021904 dorsal/ventral neural tube patterning(GO:0021904)
0.1 1.5 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.1 2.3 GO:0003334 keratinocyte development(GO:0003334)
0.1 1.6 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.9 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.4 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.1 0.7 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 2.2 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.1 3.1 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.1 3.3 GO:0030033 microvillus assembly(GO:0030033)
0.1 3.0 GO:0097503 sialylation(GO:0097503)
0.1 3.7 GO:0001510 RNA methylation(GO:0001510)
0.1 5.0 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 0.7 GO:0014050 negative regulation of glutamate secretion(GO:0014050)
0.1 1.3 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.1 2.8 GO:0035640 exploration behavior(GO:0035640)
0.1 1.4 GO:0007625 grooming behavior(GO:0007625)
0.1 2.5 GO:0006972 hyperosmotic response(GO:0006972)
0.1 0.5 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 2.8 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 7.8 GO:0030279 negative regulation of ossification(GO:0030279)
0.1 2.8 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 0.9 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.1 4.5 GO:0031648 protein destabilization(GO:0031648)
0.1 3.4 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.1 1.2 GO:0032494 response to peptidoglycan(GO:0032494)
0.1 2.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 2.8 GO:0043243 positive regulation of protein complex disassembly(GO:0043243)
0.1 1.7 GO:0051194 positive regulation of glycolytic process(GO:0045821) positive regulation of cofactor metabolic process(GO:0051194) positive regulation of coenzyme metabolic process(GO:0051197)
0.1 0.3 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 1.2 GO:0016540 protein autoprocessing(GO:0016540)
0.1 2.2 GO:0048168 regulation of neuronal synaptic plasticity(GO:0048168)
0.1 2.0 GO:0003091 renal water homeostasis(GO:0003091)
0.1 1.7 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1 5.2 GO:0016486 peptide hormone processing(GO:0016486)
0.1 5.6 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.5 GO:0097264 self proteolysis(GO:0097264)
0.1 11.1 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.1 0.7 GO:0043586 tongue development(GO:0043586)
0.1 0.5 GO:0055057 neuronal stem cell division(GO:0036445) neuroblast division(GO:0055057)
0.1 0.8 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.1 1.1 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.1 1.8 GO:0018023 peptidyl-lysine trimethylation(GO:0018023)
0.1 1.1 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.1 1.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 1.0 GO:0048485 sympathetic nervous system development(GO:0048485)
0.1 0.7 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.5 GO:0048840 otolith development(GO:0048840)
0.1 0.4 GO:0071386 cellular response to corticosterone stimulus(GO:0071386)
0.1 5.5 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.1 1.5 GO:0044804 nucleophagy(GO:0044804)
0.1 1.5 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 1.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.5 GO:0051414 response to cortisol(GO:0051414)
0.1 1.1 GO:0035855 megakaryocyte development(GO:0035855)
0.1 2.1 GO:0050691 regulation of defense response to virus by host(GO:0050691)
0.1 4.9 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.6 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 1.0 GO:0006552 leucine catabolic process(GO:0006552)
0.1 1.6 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 1.6 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 1.9 GO:0071218 cellular response to misfolded protein(GO:0071218)
0.1 3.2 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.1 0.3 GO:0048664 neuron fate determination(GO:0048664)
0.1 3.1 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.1 18.1 GO:0007601 visual perception(GO:0007601)
0.1 0.9 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.1 8.3 GO:0070268 cornification(GO:0070268)
0.1 0.6 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.1 1.2 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 1.7 GO:0000729 DNA double-strand break processing(GO:0000729)
0.1 3.1 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.1 3.6 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.6 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.1 2.9 GO:0050909 sensory perception of taste(GO:0050909)
0.1 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.4 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 1.3 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.1 2.2 GO:0050806 positive regulation of synaptic transmission(GO:0050806)
0.1 1.6 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.1 2.3 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.1 3.8 GO:0015914 phospholipid transport(GO:0015914)
0.1 0.9 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.1 0.5 GO:0070307 lens fiber cell development(GO:0070307)
0.1 4.8 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.1 0.7 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.1 1.1 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 0.5 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.1 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 2.1 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 1.6 GO:0034260 negative regulation of GTPase activity(GO:0034260)
0.1 1.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 9.9 GO:0070588 calcium ion transmembrane transport(GO:0070588)
0.1 1.0 GO:0009880 embryonic pattern specification(GO:0009880)
0.1 1.4 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 1.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 5.8 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.8 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.0 4.3 GO:0007286 spermatid development(GO:0007286)
0.0 0.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.3 GO:0045176 apical protein localization(GO:0045176)
0.0 1.1 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
0.0 0.5 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.2 GO:1902857 nonmotile primary cilium assembly(GO:0035058) regulation of nonmotile primary cilium assembly(GO:1902855) positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 2.3 GO:0006970 response to osmotic stress(GO:0006970)
0.0 2.5 GO:0010508 positive regulation of autophagy(GO:0010508)
0.0 1.8 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.5 GO:0040020 regulation of meiotic nuclear division(GO:0040020)
0.0 1.2 GO:0051693 actin filament capping(GO:0051693)
0.0 1.5 GO:0050434 positive regulation of viral transcription(GO:0050434)
0.0 0.8 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 2.0 GO:0070671 interleukin-12-mediated signaling pathway(GO:0035722) response to interleukin-12(GO:0070671) cellular response to interleukin-12(GO:0071349)
0.0 2.9 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.9 GO:0019228 neuronal action potential(GO:0019228)
0.0 1.0 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.5 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 1.3 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 2.7 GO:0050709 negative regulation of protein secretion(GO:0050709)
0.0 0.4 GO:0034063 stress granule assembly(GO:0034063)
0.0 1.7 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 1.8 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.1 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659)
0.0 3.4 GO:0030449 regulation of complement activation(GO:0030449)
0.0 0.3 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 2.2 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 1.8 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.2 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.0 GO:0043335 protein unfolding(GO:0043335)
0.0 2.2 GO:0007586 digestion(GO:0007586)
0.0 0.1 GO:0032228 regulation of synaptic transmission, GABAergic(GO:0032228) synaptic transmission, GABAergic(GO:0051932)
0.0 0.6 GO:0048278 vesicle docking(GO:0048278)
0.0 1.0 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.0 0.9 GO:0098869 cellular oxidant detoxification(GO:0098869)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 12.2 GO:0043293 apoptosome(GO:0043293)
3.4 13.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
2.8 8.3 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
2.3 9.3 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
2.2 10.8 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
1.8 9.0 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
1.7 11.7 GO:0030893 meiotic cohesin complex(GO:0030893)
1.3 3.9 GO:0000805 X chromosome(GO:0000805)
1.3 15.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
1.3 6.4 GO:1990031 pinceau fiber(GO:1990031)
1.1 10.1 GO:0044327 dendritic spine head(GO:0044327)
1.1 8.9 GO:0032593 insulin-responsive compartment(GO:0032593)
1.1 6.5 GO:0045298 tubulin complex(GO:0045298)
1.1 4.3 GO:0070695 FHF complex(GO:0070695)
1.0 5.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
1.0 5.1 GO:0005797 Golgi medial cisterna(GO:0005797)
1.0 3.9 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.9 20.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.9 17.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.9 13.5 GO:0097433 dense body(GO:0097433)
0.9 1.7 GO:0044326 dendritic spine neck(GO:0044326)
0.8 3.4 GO:0005602 complement component C1 complex(GO:0005602)
0.8 4.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.8 6.7 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.8 1.7 GO:0044308 axonal spine(GO:0044308)
0.8 12.1 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.8 11.0 GO:0098839 postsynaptic density membrane(GO:0098839)
0.8 3.0 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.7 5.0 GO:0032021 NELF complex(GO:0032021)
0.7 2.7 GO:0005899 insulin receptor complex(GO:0005899)
0.7 13.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.6 38.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.6 3.8 GO:0031501 mannosyltransferase complex(GO:0031501)
0.6 2.9 GO:0072534 perineuronal net(GO:0072534)
0.6 6.4 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.6 4.5 GO:0072487 MSL complex(GO:0072487)
0.6 11.6 GO:0071141 SMAD protein complex(GO:0071141)
0.5 7.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.5 26.2 GO:0097542 ciliary tip(GO:0097542)
0.5 16.2 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.5 10.6 GO:0033270 paranode region of axon(GO:0033270)
0.5 3.7 GO:1990635 proximal dendrite(GO:1990635)
0.5 5.1 GO:0016013 syntrophin complex(GO:0016013)
0.5 11.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.5 6.5 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.5 5.0 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.5 1.5 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.5 79.8 GO:0032587 ruffle membrane(GO:0032587)
0.5 7.7 GO:0035102 PRC1 complex(GO:0035102)
0.5 1.8 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.5 8.2 GO:0001891 phagocytic cup(GO:0001891)
0.4 3.3 GO:0000243 commitment complex(GO:0000243)
0.4 20.5 GO:0048786 presynaptic active zone(GO:0048786)
0.4 2.4 GO:0001940 male pronucleus(GO:0001940)
0.4 6.4 GO:0005883 neurofilament(GO:0005883)
0.4 4.8 GO:0032591 dendritic spine membrane(GO:0032591)
0.4 23.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.4 4.1 GO:0005955 calcineurin complex(GO:0005955)
0.4 1.8 GO:0071797 LUBAC complex(GO:0071797)
0.4 2.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.4 1.8 GO:1990909 Wnt signalosome(GO:1990909)
0.4 5.8 GO:0043194 axon initial segment(GO:0043194)
0.4 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.4 4.7 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.4 1.1 GO:0070701 mucus layer(GO:0070701)
0.3 30.4 GO:0060170 ciliary membrane(GO:0060170)
0.3 2.4 GO:0030897 HOPS complex(GO:0030897)
0.3 16.6 GO:0016235 aggresome(GO:0016235)
0.3 4.4 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.3 49.2 GO:0031901 early endosome membrane(GO:0031901)
0.3 25.7 GO:0042734 presynaptic membrane(GO:0042734)
0.3 9.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.3 3.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.3 11.0 GO:0034451 centriolar satellite(GO:0034451)
0.3 4.1 GO:0008091 spectrin(GO:0008091)
0.3 1.2 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
0.3 2.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.3 1.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.3 12.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.3 4.8 GO:0097440 apical dendrite(GO:0097440)
0.3 2.8 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 1.7 GO:0005827 polar microtubule(GO:0005827)
0.2 3.9 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.2 1.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.2 31.9 GO:0055037 recycling endosome(GO:0055037)
0.2 4.2 GO:0005922 connexon complex(GO:0005922)
0.2 2.8 GO:0030008 TRAPP complex(GO:0030008)
0.2 3.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.2 11.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 23.9 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.2 2.3 GO:0016580 Sin3 complex(GO:0016580)
0.2 2.3 GO:0016342 catenin complex(GO:0016342)
0.2 5.7 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 1.9 GO:0060076 excitatory synapse(GO:0060076)
0.2 4.5 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.2 6.4 GO:0071565 nBAF complex(GO:0071565)
0.2 5.4 GO:0032420 stereocilium(GO:0032420)
0.2 1.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.2 3.0 GO:0035631 CD40 receptor complex(GO:0035631)
0.2 2.4 GO:0070578 RISC-loading complex(GO:0070578)
0.2 2.8 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.2 1.0 GO:0033553 rDNA heterochromatin(GO:0033553)
0.2 4.4 GO:0030057 desmosome(GO:0030057)
0.2 1.7 GO:0001741 XY body(GO:0001741)
0.2 6.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 1.4 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 1.2 GO:0035976 AP1 complex(GO:0035976)
0.1 4.1 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.5 GO:0031045 dense core granule(GO:0031045)
0.1 31.6 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 18.6 GO:0070382 exocytic vesicle(GO:0070382)
0.1 1.0 GO:0005593 FACIT collagen trimer(GO:0005593)
0.1 1.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 0.9 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 2.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 1.4 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 2.8 GO:0035861 site of double-strand break(GO:0035861)
0.1 11.0 GO:0005814 centriole(GO:0005814)
0.1 4.0 GO:0016592 mediator complex(GO:0016592)
0.1 3.3 GO:0070461 SAGA-type complex(GO:0070461)
0.1 1.9 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)
0.1 4.7 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 2.8 GO:0005839 proteasome core complex(GO:0005839)
0.1 1.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.9 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.6 GO:0036038 MKS complex(GO:0036038)
0.1 0.9 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 1.5 GO:0005682 U5 snRNP(GO:0005682)
0.1 0.6 GO:0005686 U2 snRNP(GO:0005686)
0.1 1.0 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 3.1 GO:0097014 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 10.1 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.1 1.3 GO:0002080 acrosomal membrane(GO:0002080)
0.1 2.3 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 2.4 GO:0008305 integrin complex(GO:0008305)
0.1 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 6.7 GO:0098794 postsynapse(GO:0098794)
0.1 1.9 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 2.4 GO:0005844 polysome(GO:0005844)
0.0 1.8 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.6 GO:0034704 calcium channel complex(GO:0034704)
0.0 17.0 GO:0030425 dendrite(GO:0030425)
0.0 0.9 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.9 GO:0036064 ciliary basal body(GO:0036064)
0.0 4.0 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 1.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 1.4 GO:0005776 autophagosome(GO:0005776)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 5.8 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.8 GO:0031514 motile cilium(GO:0031514)
0.0 2.1 GO:0030426 growth cone(GO:0030426)
0.0 0.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.5 GO:0035579 specific granule membrane(GO:0035579)
0.0 1.6 GO:0016605 PML body(GO:0016605)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
10.1 40.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
4.6 27.9 GO:0016929 SUMO-specific protease activity(GO:0016929)
4.6 13.8 GO:0019959 interleukin-8 binding(GO:0019959)
4.4 13.1 GO:0031687 A2A adenosine receptor binding(GO:0031687)
4.0 16.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
3.1 12.5 GO:0097001 ceramide binding(GO:0097001)
3.0 9.0 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
2.7 57.6 GO:0019992 diacylglycerol binding(GO:0019992)
2.7 15.9 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
2.6 7.9 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
2.5 41.8 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
2.1 8.4 GO:0004906 interferon-gamma receptor activity(GO:0004906)
2.0 8.2 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
2.0 27.9 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
2.0 9.9 GO:0030348 syntaxin-3 binding(GO:0030348)
2.0 9.9 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
1.8 7.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
1.8 15.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
1.7 6.7 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
1.7 8.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
1.6 9.8 GO:0004305 ethanolamine kinase activity(GO:0004305)
1.6 8.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
1.6 8.0 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
1.5 4.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
1.5 15.1 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
1.5 4.5 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
1.4 4.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
1.4 4.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
1.3 10.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
1.3 3.8 GO:0004584 dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity(GO:0004584)
1.2 6.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
1.2 9.6 GO:0008046 axon guidance receptor activity(GO:0008046)
1.2 7.2 GO:0008142 oxysterol binding(GO:0008142)
1.2 11.9 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
1.1 8.0 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
1.1 18.9 GO:0003680 AT DNA binding(GO:0003680)
1.1 6.7 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
1.1 5.5 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
1.1 53.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
1.1 5.3 GO:0042610 CD8 receptor binding(GO:0042610)
1.0 4.2 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
1.0 8.0 GO:0016433 rRNA (adenine) methyltransferase activity(GO:0016433)
1.0 2.9 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
1.0 5.7 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.9 3.8 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.9 14.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.9 4.7 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.9 5.4 GO:0031685 adenosine receptor binding(GO:0031685)
0.9 7.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.9 0.9 GO:1904455 ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455)
0.9 4.3 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.9 19.7 GO:0001223 transcription coactivator binding(GO:0001223)
0.8 3.3 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.8 2.5 GO:0030290 sphingolipid activator protein activity(GO:0030290) beta-N-acetylgalactosaminidase activity(GO:0032428)
0.8 9.0 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.8 6.5 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.8 6.5 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.8 4.0 GO:0031762 alpha-1A adrenergic receptor binding(GO:0031691) follicle-stimulating hormone receptor binding(GO:0031762)
0.8 19.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.8 13.4 GO:0070411 I-SMAD binding(GO:0070411)
0.8 19.7 GO:0017075 syntaxin-1 binding(GO:0017075)
0.8 4.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.8 2.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.8 17.8 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.8 9.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.8 1.5 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.8 3.8 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.7 5.9 GO:0052833 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.7 2.9 GO:0035500 MH2 domain binding(GO:0035500)
0.7 6.4 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.7 0.7 GO:0097108 smoothened binding(GO:0005119) hedgehog family protein binding(GO:0097108)
0.7 2.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.7 17.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.7 2.8 GO:0048408 epidermal growth factor binding(GO:0048408)
0.7 2.8 GO:0004513 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.7 2.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662) Toll-like receptor 2 binding(GO:0035663)
0.7 4.6 GO:0097322 7SK snRNA binding(GO:0097322)
0.6 5.8 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.6 4.3 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.6 4.8 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.6 12.0 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.6 2.3 GO:0004077 biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
0.6 7.3 GO:0035497 cAMP response element binding(GO:0035497)
0.6 4.5 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.6 3.9 GO:0005113 patched binding(GO:0005113)
0.5 2.2 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.5 2.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.5 7.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.5 2.0 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.5 8.4 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.5 1.5 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.5 3.9 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.5 1.9 GO:0070644 vitamin D response element binding(GO:0070644)
0.5 1.8 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.5 16.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.5 1.8 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.5 1.4 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.4 1.3 GO:0045499 chemorepellent activity(GO:0045499)
0.4 2.2 GO:0043398 HLH domain binding(GO:0043398)
0.4 3.5 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.4 1.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.4 1.7 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.4 0.4 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.4 2.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.4 22.5 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.4 15.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.4 3.7 GO:0009374 biotin binding(GO:0009374)
0.4 2.9 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.4 11.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.4 9.5 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.4 2.8 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.4 2.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.4 1.9 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.4 1.2 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.4 9.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.4 3.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.4 5.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.4 6.9 GO:0043274 phospholipase binding(GO:0043274)
0.4 3.0 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.4 1.1 GO:0000247 C-8 sterol isomerase activity(GO:0000247)
0.4 4.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.4 1.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.4 1.5 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.4 1.4 GO:0003990 acetylcholinesterase activity(GO:0003990) cholinesterase activity(GO:0004104)
0.4 2.1 GO:0039552 RIG-I binding(GO:0039552)
0.3 6.9 GO:0097109 neuroligin family protein binding(GO:0097109)
0.3 2.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.3 5.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.3 5.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.3 1.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.3 1.3 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.3 1.7 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.3 10.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.3 1.0 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.3 1.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.3 1.6 GO:0070573 metallodipeptidase activity(GO:0070573)
0.3 3.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.3 9.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.3 3.3 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.3 3.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.3 1.8 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3 2.0 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.3 0.9 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.3 6.6 GO:0031005 filamin binding(GO:0031005)
0.3 1.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.3 2.0 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.3 4.2 GO:0005243 gap junction channel activity(GO:0005243)
0.3 1.7 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.3 2.2 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.3 3.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.3 8.7 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.3 2.8 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 2.2 GO:0004969 histamine receptor activity(GO:0004969)
0.2 3.0 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.2 7.9 GO:0030552 cAMP binding(GO:0030552)
0.2 2.2 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.2 7.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.2 6.8 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.2 18.1 GO:0005262 calcium channel activity(GO:0005262)
0.2 9.8 GO:0030332 cyclin binding(GO:0030332)
0.2 1.6 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.2 4.7 GO:0005522 profilin binding(GO:0005522)
0.2 2.6 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.2 9.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.2 2.5 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.2 2.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.2 7.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.2 4.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.2 0.9 GO:1901375 acetylcholine transmembrane transporter activity(GO:0005277) acetate ester transmembrane transporter activity(GO:1901375)
0.2 0.6 GO:0008476 protein-tyrosine sulfotransferase activity(GO:0008476)
0.2 1.0 GO:0050436 microfibril binding(GO:0050436)
0.2 5.1 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.2 5.8 GO:0030506 ankyrin binding(GO:0030506)
0.2 1.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.2 3.1 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 0.8 GO:0035939 microsatellite binding(GO:0035939)
0.2 0.8 GO:0005497 androgen binding(GO:0005497)
0.2 10.5 GO:0015485 cholesterol binding(GO:0015485)
0.2 6.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 1.5 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.2 3.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 5.5 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.2 9.7 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 6.6 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.2 5.6 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.2 0.9 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.2 3.9 GO:0005003 ephrin receptor activity(GO:0005003)
0.2 1.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 0.5 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.2 6.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.2 0.7 GO:0070905 serine binding(GO:0070905)
0.2 12.5 GO:0008080 N-acetyltransferase activity(GO:0008080)
0.2 0.7 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.2 0.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 1.3 GO:0008430 selenium binding(GO:0008430)
0.2 4.0 GO:0070064 proline-rich region binding(GO:0070064)
0.2 10.8 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 5.3 GO:0005109 frizzled binding(GO:0005109)
0.1 1.2 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 3.5 GO:0071837 HMG box domain binding(GO:0071837)
0.1 1.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 1.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.6 GO:0008158 hedgehog receptor activity(GO:0008158)
0.1 0.7 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.7 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.1 1.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 2.0 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.7 GO:0004803 transposase activity(GO:0004803)
0.1 9.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 10.1 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 2.4 GO:0050811 GABA receptor binding(GO:0050811)
0.1 3.4 GO:0050780 dopamine receptor binding(GO:0050780)
0.1 3.2 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 4.5 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 5.0 GO:0004385 guanylate kinase activity(GO:0004385)
0.1 1.4 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.1 0.8 GO:0045545 syndecan binding(GO:0045545)
0.1 3.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 9.0 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 2.6 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 4.7 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 27.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.7 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 1.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.3 GO:0008502 melatonin receptor activity(GO:0008502)
0.1 1.0 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.1 0.4 GO:0022840 leak channel activity(GO:0022840) potassium ion leak channel activity(GO:0022841) narrow pore channel activity(GO:0022842)
0.1 1.9 GO:0019206 nucleoside kinase activity(GO:0019206)
0.1 12.3 GO:0005085 guanyl-nucleotide exchange factor activity(GO:0005085)
0.1 34.0 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 0.5 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 3.7 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.1 1.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 5.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 4.7 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.1 4.9 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 1.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 3.0 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 0.4 GO:0097016 L27 domain binding(GO:0097016)
0.1 1.9 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 3.5 GO:0030507 spectrin binding(GO:0030507)
0.1 1.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 1.1 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 2.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.1 0.2 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 4.1 GO:0004521 endoribonuclease activity(GO:0004521)
0.1 1.5 GO:0005521 lamin binding(GO:0005521)
0.1 3.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 4.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.1 1.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 0.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 16.6 GO:0005096 GTPase activator activity(GO:0005096)
0.1 0.9 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.1 1.2 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 1.0 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.1 0.7 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 1.4 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.5 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 4.3 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.9 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185) serine-type exopeptidase activity(GO:0070008)
0.0 0.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.1 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 3.9 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.9 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.0 GO:0000049 tRNA binding(GO:0000049)
0.0 1.0 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 1.2 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.3 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.0 0.1 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 1.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.3 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 0.8 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.5 GO:0035254 glutamate receptor binding(GO:0035254)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.1 GO:0046790 virion binding(GO:0046790)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 95.8 PID RAS PATHWAY Regulation of Ras family activation
1.1 42.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.8 43.7 PID REELIN PATHWAY Reelin signaling pathway
0.6 10.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.6 9.5 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.5 3.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.5 32.6 PID TNF PATHWAY TNF receptor signaling pathway
0.5 29.2 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.5 4.6 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.4 9.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.4 5.8 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.4 1.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.4 7.9 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 2.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.3 6.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.3 12.1 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.3 7.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.3 17.2 PID RHOA PATHWAY RhoA signaling pathway
0.3 8.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.3 20.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.3 6.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.3 2.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.3 14.3 PID ARF6 PATHWAY Arf6 signaling events
0.2 12.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.2 2.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.2 3.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 4.8 PID IL27 PATHWAY IL27-mediated signaling events
0.2 2.6 PID EPHB FWD PATHWAY EPHB forward signaling
0.2 4.6 PID IFNG PATHWAY IFN-gamma pathway
0.2 6.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.2 23.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.2 9.6 PID FANCONI PATHWAY Fanconi anemia pathway
0.2 1.2 PID CD40 PATHWAY CD40/CD40L signaling
0.2 2.1 PID NOTCH PATHWAY Notch signaling pathway
0.2 1.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2 4.0 ST GAQ PATHWAY G alpha q Pathway
0.2 8.8 PID ERBB4 PATHWAY ErbB4 signaling events
0.2 3.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.2 1.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 7.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.2 11.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.2 1.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 3.3 PID CONE PATHWAY Visual signal transduction: Cones
0.1 2.0 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.1 7.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 7.0 PID AURORA B PATHWAY Aurora B signaling
0.1 3.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 7.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.7 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 7.0 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 2.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 1.8 PID INSULIN PATHWAY Insulin Pathway
0.1 2.4 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.1 1.3 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 5.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.7 SIG CHEMOTAXIS Genes related to chemotaxis
0.1 2.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 6.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 1.4 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.9 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 1.5 PID ARF 3PATHWAY Arf1 pathway
0.1 1.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.1 1.0 PID SHP2 PATHWAY SHP2 signaling
0.1 0.9 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 2.3 PID FGF PATHWAY FGF signaling pathway
0.0 3.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.5 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.8 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 1.0 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.2 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.9 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.2 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.7 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.4 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 3.4 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
1.5 33.9 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
1.4 55.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
1.3 42.3 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
1.3 6.5 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
1.1 16.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
1.1 9.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
1.0 23.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.9 8.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.8 9.7 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.8 16.1 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.8 13.8 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.7 11.9 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.7 8.7 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.7 14.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.7 1.3 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.6 36.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.6 28.0 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.6 10.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.6 24.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.6 1.7 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.6 8.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.5 20.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.5 10.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.5 7.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.5 2.7 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.4 6.6 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.4 16.3 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.4 8.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.4 9.8 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.3 7.1 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.3 7.2 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.3 3.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.3 6.4 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.3 5.1 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.3 13.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.2 1.7 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.2 7.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.2 7.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 5.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 7.2 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.2 14.1 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.2 3.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.2 4.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 12.5 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.2 6.7 REACTOME AMYLOIDS Genes involved in Amyloids
0.2 0.6 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.2 2.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 2.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.2 2.8 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.2 4.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.2 3.6 REACTOME FRS2 MEDIATED CASCADE Genes involved in FRS2-mediated cascade
0.2 5.1 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 11.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 3.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 2.0 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.2 4.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.2 4.1 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.2 3.3 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.2 8.7 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.2 3.0 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.2 1.8 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.1 4.6 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 2.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 7.6 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 5.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 2.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.6 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.1 16.6 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 1.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 1.2 REACTOME CD28 DEPENDENT PI3K AKT SIGNALING Genes involved in CD28 dependent PI3K/Akt signaling
0.1 2.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.1 2.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 4.1 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 4.7 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 0.9 REACTOME INFLUENZA LIFE CYCLE Genes involved in Influenza Life Cycle
0.1 2.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 0.9 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.1 0.8 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 2.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 3.8 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.1 2.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.1 1.4 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1 0.5 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 3.1 REACTOME SIGNALING BY NOTCH1 Genes involved in Signaling by NOTCH1
0.1 1.5 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 0.7 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.1 1.9 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 2.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.3 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 1.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 4.2 REACTOME GPCR LIGAND BINDING Genes involved in GPCR ligand binding
0.1 1.2 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 1.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 1.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 4.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.8 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.0 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.0 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.8 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.3 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 1.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 2.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism