ISMARA results: ELF2_GABPA

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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ELF2_GABPA_ELF5

Z-value: 12.17

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Transcription factors associated with ELF2_GABPA_ELF5

Gene Symbol	Gene ID	Gene Info
ELF2 Ensembl NCBI GeneCards UniProt	ENSG00000109381.20	ELF2
GABPA Ensembl NCBI GeneCards UniProt	ENSG00000154727.11	GABPA
ELF5 Ensembl NCBI GeneCards UniProt	ENSG00000135374.11	ELF5

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
ELF2	hg38_v1_chr4_-_139084289_139084496	0.43	3.2e-11	Click!
ELF5	hg38_v1_chr11_-_34513785_34513805	-0.33	7.9e-07	Click!
GABPA	hg38_v1_chr21_+_25734948_25734988	0.30	5.9e-06	Click!

Activity profile of ELF2_GABPA_ELF5 motif

Sorted Z-values of ELF2_GABPA_ELF5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ELF2_GABPA_ELF5

View svg image
View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr1_+_32222415 Show fit	232.20	ENST00000678420.1 ENST00000678162.1 ENST00000678711.1 ENST00000678883.1 ENST00000677353.1 ENST00000355082.10	EIF3I Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 3 subunit I
chr1_+_32222393 Show fit	221.35	ENST00000676679.1 ENST00000678689.1 ENST00000373586.2 ENST00000679290.1 ENST00000677378.1 ENST00000678534.1 ENST00000678968.1 ENST00000678063.1 ENST00000678150.1 ENST00000677198.1 ENST00000677540.1	EIF3I Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 3 subunit I
chr12_-_110450298 Show fit	204.63	ENST00000426440.5 ENST00000228825.12	ARPC3 Ensembl NCBI GeneCards UniProt Show fit	actin related protein 2/3 complex subunit 3
chr20_-_50958520 Show fit	196.00	ENST00000371588.10 ENST00000371584.9 ENST00000413082.1 ENST00000371582.8	DPM1 Ensembl NCBI GeneCards UniProt Show fit	dolichyl-phosphate mannosyltransferase subunit 1, catalytic
chr2_-_73737320 Show fit	187.40	ENST00000272424.11	TPRKB Ensembl NCBI GeneCards UniProt Show fit	TP53RK binding protein
chr2_-_73737374 Show fit	167.03	ENST00000318190.7 ENST00000409716.6	TPRKB Ensembl NCBI GeneCards UniProt Show fit	TP53RK binding protein
chr1_+_203861575 Show fit	159.38	ENST00000414487.7	SNRPE Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptide E
chr5_+_110738983 Show fit	159.13	ENST00000355943.8 ENST00000447245.6	SLC25A46 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 25 member 46
chr5_+_271616 Show fit	151.56	ENST00000614778.4 ENST00000618970.4 ENST00000628729.2	PDCD6 Ensembl NCBI GeneCards UniProt Show fit	programmed cell death 6
chr12_+_68686951 Show fit	149.31	ENST00000378905.6 ENST00000229179.9	NUP107 Ensembl NCBI GeneCards UniProt Show fit	nucleoporin 107
chr1_+_40040219 Show fit	148.12	ENST00000372797.7 ENST00000372802.5 ENST00000449311.5	CAP1 Ensembl NCBI GeneCards UniProt Show fit	cyclase associated actin cytoskeleton regulatory protein 1
chr20_-_2470749 Show fit	146.87	ENST00000381342.7 ENST00000438552.6	SNRPB Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptides B and B1
chr2_+_65228122 Show fit	140.99	ENST00000542850.2	ACTR2 Ensembl NCBI GeneCards UniProt Show fit	actin related protein 2
chr15_+_78540729 Show fit	140.36	ENST00000559365.5 ENST00000558341.5 ENST00000559437.5	PSMA4 Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit alpha 4
chr10_+_42782769 Show fit	140.33	ENST00000374518.6	BMS1 Ensembl NCBI GeneCards UniProt Show fit	BMS1 ribosome biogenesis factor
chr22_-_36528897 Show fit	139.74	ENST00000405442.5 ENST00000402116.2	EIF3D Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 3 subunit D
chr3_-_32502783 Show fit	139.08	ENST00000205636.4	CMTM6 Ensembl NCBI GeneCards UniProt Show fit	CKLF like MARVEL transmembrane domain containing 6
chr11_-_64245816 Show fit	137.18	ENST00000542235.1	PPP1R14B Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory inhibitor subunit 14B
chr1_-_165768835 Show fit	135.81	ENST00000481278.5	TMCO1 Ensembl NCBI GeneCards UniProt Show fit	transmembrane and coiled-coil domains 1
chr5_+_168486462 Show fit	133.96	ENST00000231572.8 ENST00000626454.1	RARS1 Ensembl NCBI GeneCards UniProt Show fit	arginyl-tRNA synthetase 1
chr1_+_40040720 Show fit	133.16	ENST00000414893.5 ENST00000372792.7 ENST00000372805.8 ENST00000414281.5 ENST00000420216.5 ENST00000372798.5 ENST00000340450.7 ENST00000435719.5 ENST00000427843.5 ENST00000417287.5 ENST00000424977.1	CAP1 Ensembl NCBI GeneCards UniProt Show fit	cyclase associated actin cytoskeleton regulatory protein 1
chr5_+_271637 Show fit	133.07	ENST00000264933.9 ENST00000505221.5 ENST00000509581.5 ENST00000507528.5	PDCD6 Ensembl NCBI GeneCards UniProt Show fit	programmed cell death 6
chr2_-_37231549 Show fit	132.31	ENST00000234170.10	CEBPZ Ensembl NCBI GeneCards UniProt Show fit	CCAAT enhancer binding protein zeta
chr2_+_65227792 Show fit	132.20	ENST00000260641.10 ENST00000377982.8	ACTR2 Ensembl NCBI GeneCards UniProt Show fit	actin related protein 2
chr3_-_131502946 Show fit	131.36	ENST00000512877.1 ENST00000264995.8 ENST00000511168.5 ENST00000425847.6	MRPL3 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L3
chr14_+_35292374 Show fit	131.20	ENST00000261479.9 ENST00000553809.5	PSMA6 Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit alpha 6
chr21_-_32612339 Show fit	127.48	ENST00000440966.5 ENST00000290155.8	CFAP298 Ensembl NCBI GeneCards UniProt Show fit	cilia and flagella associated protein 298
chr19_-_10339610 Show fit	127.07	ENST00000589261.5 ENST00000160262.10 ENST00000590569.1 ENST00000589580.1 ENST00000589249.1	ICAM3 Ensembl NCBI GeneCards UniProt Show fit	intercellular adhesion molecule 3
chr22_-_36529136 Show fit	126.43	ENST00000216190.13 ENST00000455547.5	EIF3D Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 3 subunit D
chr7_-_7640971 Show fit	126.40	ENST00000396682.6	RPA3 Ensembl NCBI GeneCards UniProt Show fit	replication protein A3
chr10_-_43409160 Show fit	126.14	ENST00000337970.7 ENST00000682386.1	HNRNPF Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein F
chr21_-_32612577 Show fit	125.98	ENST00000673985.1 ENST00000382549.8	CFAP298-TCP10L Ensembl NCBI GeneCards UniProt Show fit CFAP298 Ensembl NCBI GeneCards UniProt Show fit	CFAP298-TCP10L readthrough cilia and flagella associated protein 298
chr11_-_67401782 Show fit	125.78	ENST00000527663.6 ENST00000312989.11 ENST00000376745.9 ENST00000358239.8	PPP1CA Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 catalytic subunit alpha
chr10_+_12196172 Show fit	123.61	ENST00000281141.9 ENST00000378900.6 ENST00000442050.5	CDC123 Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 123
chr3_-_186806445 Show fit	122.88	ENST00000418288.5 ENST00000296273.7	RFC4 Ensembl NCBI GeneCards UniProt Show fit	replication factor C subunit 4
chr11_-_67401560 Show fit	120.74	ENST00000679175.1	PPP1CA Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 catalytic subunit alpha
chr8_-_54101855 Show fit	120.47	ENST00000522007.5 ENST00000521898.5 ENST00000316963.8 ENST00000518546.5	LYPLA1 Ensembl NCBI GeneCards UniProt Show fit	lysophospholipase 1
chr2_-_229921903 Show fit	120.44	ENST00000389045.7 ENST00000409677.5	TRIP12 Ensembl NCBI GeneCards UniProt Show fit	thyroid hormone receptor interactor 12
chr11_+_32583792 Show fit	119.73	ENST00000531120.6 ENST00000524896.5 ENST00000323213.9	EIF3M Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 3 subunit M
chr4_+_70688511 Show fit	119.11	ENST00000254803.4	UTP3 Ensembl NCBI GeneCards UniProt Show fit	UTP3 small subunit processome component
chr11_+_66002754 Show fit	118.61	ENST00000527348.1	BANF1 Ensembl NCBI GeneCards UniProt Show fit	BAF nuclear assembly factor 1
chr14_+_35292308 Show fit	117.12	ENST00000628955.1 ENST00000627895.2 ENST00000622405.4	PSMA6 Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit alpha 6
chr20_+_16729961 Show fit	116.85	ENST00000377943.9 ENST00000246071.8	SNRPB2 Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptide B2
chr5_-_141320755 Show fit	113.83	ENST00000624761.1 ENST00000313368.8	TAF7 Ensembl NCBI GeneCards UniProt Show fit	TATA-box binding protein associated factor 7
chr11_-_64317528 Show fit	113.71	ENST00000308774.6 ENST00000544844.6	TRMT112 Ensembl NCBI GeneCards UniProt Show fit	tRNA methyltransferase subunit 11-2
chr18_+_3247415 Show fit	112.28	ENST00000579226.5	MYL12A Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 12A
chr8_-_54101979 Show fit	111.87	ENST00000618914.4	LYPLA1 Ensembl NCBI GeneCards UniProt Show fit	lysophospholipase 1
chr13_-_30617500 Show fit	111.18	ENST00000405805.5	HMGB1 Ensembl NCBI GeneCards UniProt Show fit	high mobility group box 1
chr8_-_54022441 Show fit	111.17	ENST00000396401.7 ENST00000521604.7 ENST00000640382.1 ENST00000640041.1	TCEA1 Ensembl NCBI GeneCards UniProt Show fit	transcription elongation factor A1
chr17_+_59707636 Show fit	111.13	ENST00000262291.9 ENST00000587945.1 ENST00000589823.6 ENST00000592106.5 ENST00000591315.5	VMP1 Ensembl NCBI GeneCards UniProt Show fit	vacuole membrane protein 1
chr10_-_27154365 Show fit	110.74	ENST00000396296.7 ENST00000376016.8 ENST00000491542.6 ENST00000613434.4	YME1L1 Ensembl NCBI GeneCards UniProt Show fit	YME1 like 1 ATPase
chr1_+_84479239 Show fit	110.33	ENST00000370656.5 ENST00000370654.6	RPF1 Ensembl NCBI GeneCards UniProt Show fit	ribosome production factor 1 homolog
chr17_-_8210565 Show fit	109.09	ENST00000577833.5 ENST00000585124.6 ENST00000534871.5 ENST00000583915.1 ENST00000316199.10 ENST00000581511.5	AURKB Ensembl NCBI GeneCards UniProt Show fit	aurora kinase B
chr10_-_43397220 Show fit	108.93	ENST00000477108.5 ENST00000544000.5	HNRNPF Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein F
chr2_+_117814648 Show fit	108.87	ENST00000263239.7	DDX18 Ensembl NCBI GeneCards UniProt Show fit	DEAD-box helicase 18
chr7_+_141738343 Show fit	108.76	ENST00000498107.5 ENST00000265304.11 ENST00000467681.5 ENST00000465582.5 ENST00000463093.5	SSBP1 Ensembl NCBI GeneCards UniProt Show fit	single stranded DNA binding protein 1
chr19_+_13150386 Show fit	108.55	ENST00000292433.4 ENST00000587885.1	IER2 Ensembl NCBI GeneCards UniProt Show fit	immediate early response 2
chr19_+_29606274 Show fit	108.43	ENST00000586420.5 ENST00000585603.6 ENST00000221770.7 ENST00000590688.1	POP4 Ensembl NCBI GeneCards UniProt Show fit	POP4 homolog, ribonuclease P/MRP subunit
chr7_+_141738321 Show fit	107.43	ENST00000612337.4	SSBP1 Ensembl NCBI GeneCards UniProt Show fit	single stranded DNA binding protein 1
chr11_+_62761536 Show fit	106.54	ENST00000533442.5	POLR2G Ensembl NCBI GeneCards UniProt Show fit	RNA polymerase II subunit G
chr18_+_3247778 Show fit	106.00	ENST00000217652.8 ENST00000578611.5 ENST00000583449.1	MYL12A Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 12A
chr5_+_892844 Show fit	104.94	ENST00000166345.8	TRIP13 Ensembl NCBI GeneCards UniProt Show fit	thyroid hormone receptor interactor 13
chr1_+_40258202 Show fit	104.17	ENST00000372759.4	ZMPSTE24 Ensembl NCBI GeneCards UniProt Show fit	zinc metallopeptidase STE24
chr1_+_23691742 Show fit	103.96	ENST00000374550.8 ENST00000643754.2	RPL11 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L11
chr8_-_120445092 Show fit	103.66	ENST00000518918.1	MRPL13 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L13
chr8_-_54101458 Show fit	103.35	ENST00000521352.5 ENST00000618741.1	LYPLA1 Ensembl NCBI GeneCards UniProt Show fit	lysophospholipase 1
chr6_-_31542339 Show fit	103.33	ENST00000458640.5	DDX39B Ensembl NCBI GeneCards UniProt Show fit	DExD-box helicase 39B
chr17_-_59707404 Show fit	103.33	ENST00000393038.3	PTRH2 Ensembl NCBI GeneCards UniProt Show fit	peptidyl-tRNA hydrolase 2
chr6_-_31736504 Show fit	102.48	ENST00000616760.1 ENST00000375784.7 ENST00000375779.6	CLIC1 Ensembl NCBI GeneCards UniProt Show fit	chloride intracellular channel 1
chr18_+_3262098 Show fit	102.43	ENST00000237500.10	MYL12B Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 12B
chr8_-_54101777 Show fit	101.66	ENST00000343231.10	LYPLA1 Ensembl NCBI GeneCards UniProt Show fit	lysophospholipase 1
chr10_-_43408787 Show fit	101.55	ENST00000356053.7	HNRNPF Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein F
chr1_-_156020789 Show fit	101.07	ENST00000531917.5 ENST00000480567.5 ENST00000526212.2 ENST00000529008.5 ENST00000496742.5 ENST00000295702.9	SSR2 Ensembl NCBI GeneCards UniProt Show fit	signal sequence receptor subunit 2
chr4_-_99894368 Show fit	100.65	ENST00000226522.8 ENST00000499666.7	LAMTOR3 Ensembl NCBI GeneCards UniProt Show fit	late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
chr11_+_66002225 Show fit	100.43	ENST00000445560.6 ENST00000530204.1	BANF1 Ensembl NCBI GeneCards UniProt Show fit	BAF nuclear assembly factor 1
chr12_-_112418819 Show fit	100.35	ENST00000551291.6	RPL6 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L6
chr2_+_161308407 Show fit	99.68	ENST00000409682.8	PSMD14 Ensembl NCBI GeneCards UniProt Show fit	proteasome 26S subunit, non-ATPase 14
chr1_+_93345893 Show fit	99.53	ENST00000370272.9 ENST00000370267.1	DR1 Ensembl NCBI GeneCards UniProt Show fit	down-regulator of transcription 1
chr3_-_146544701 Show fit	99.51	ENST00000487389.5	PLSCR1 Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 1
chr6_-_31958852 Show fit	99.03	ENST00000375425.9 ENST00000426722.5	NELFE Ensembl NCBI GeneCards UniProt Show fit	negative elongation factor complex member E
chr20_+_3209469 Show fit	98.42	ENST00000380113.8 ENST00000455664.6 ENST00000399838.3	ITPA Ensembl NCBI GeneCards UniProt Show fit	inosine triphosphatase
chr11_+_62761570 Show fit	98.13	ENST00000301788.12	POLR2G Ensembl NCBI GeneCards UniProt Show fit	RNA polymerase II subunit G
chr14_+_35292429 Show fit	97.98	ENST00000555764.5 ENST00000556506.1	PSMA6 Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit alpha 6
chr17_-_8210203 Show fit	97.66	ENST00000578549.5 ENST00000582368.5	AURKB Ensembl NCBI GeneCards UniProt Show fit	aurora kinase B
chr2_-_99336306 Show fit	97.43	ENST00000264255.8 ENST00000409434.5 ENST00000434323.5	TXNDC9 Ensembl NCBI GeneCards UniProt Show fit	thioredoxin domain containing 9
chr20_+_408030 Show fit	97.37	ENST00000640614.1 ENST00000475269.5	RBCK1 Ensembl NCBI GeneCards UniProt Show fit	RANBP2-type and C3HC4-type zinc finger containing 1
chr10_-_27154226 Show fit	96.84	ENST00000427324.5 ENST00000375972.7 ENST00000326799.7	YME1L1 Ensembl NCBI GeneCards UniProt Show fit	YME1 like 1 ATPase
chr11_+_59144767 Show fit	96.51	ENST00000527629.6 ENST00000361723.7 ENST00000531408.6 ENST00000420244.6	FAM111A Ensembl NCBI GeneCards UniProt Show fit	FAM111 trypsin like peptidase A
chr11_-_58578096 Show fit	94.84	ENST00000528954.5 ENST00000528489.1	LPXN Ensembl NCBI GeneCards UniProt Show fit	leupaxin
chr6_-_31958935 Show fit	93.97	ENST00000441998.5 ENST00000444811.6 ENST00000375429.8	NELFE Ensembl NCBI GeneCards UniProt Show fit	negative elongation factor complex member E
chr16_-_30193666 Show fit	93.01	ENST00000651894.2 ENST00000569282.2 ENST00000567436.2	BOLA2B Ensembl NCBI GeneCards UniProt Show fit	bolA family member 2B
chr19_-_55407719 Show fit	92.45	ENST00000587845.5 ENST00000589978.1 ENST00000264552.14	UBE2S Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 S
chr8_-_116766255 Show fit	91.38	ENST00000276682.8	EIF3H Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 3 subunit H
chr3_-_64023424 Show fit	91.35	ENST00000478185.1 ENST00000482510.5 ENST00000497323.5 ENST00000492933.5 ENST00000295901.9	PSMD6 Ensembl NCBI GeneCards UniProt Show fit	proteasome 26S subunit, non-ATPase 6
chr2_+_201071984 Show fit	91.25	ENST00000237889.9 ENST00000433898.5 ENST00000684175.1 ENST00000682325.1 ENST00000454214.1 ENST00000684420.1	NDUFB3 Ensembl NCBI GeneCards UniProt Show fit	NADH:ubiquinone oxidoreductase subunit B3
chr7_-_54759182 Show fit	90.98	ENST00000450622.1 ENST00000352861.9 ENST00000395535.7	SEC61G Ensembl NCBI GeneCards UniProt Show fit	SEC61 translocon subunit gamma
chr7_+_99408609 Show fit	90.59	ENST00000403633.6	BUD31 Ensembl NCBI GeneCards UniProt Show fit	BUD31 homolog
chr8_+_144358633 Show fit	89.91	ENST00000675280.1	SLC52A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 52 member 2
chr16_+_30075967 Show fit	89.29	ENST00000279387.12 ENST00000562664.5 ENST00000627746.2 ENST00000562222.5	PPP4C Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 4 catalytic subunit
chr5_+_74766981 Show fit	89.10	ENST00000296802.9	NSA2 Ensembl NCBI GeneCards UniProt Show fit	NSA2 ribosome biogenesis factor
chr22_-_37244417 Show fit	88.79	ENST00000405484.5 ENST00000441619.5 ENST00000406508.5	RAC2 Ensembl NCBI GeneCards UniProt Show fit	Rac family small GTPase 2
chr1_-_8878706 Show fit	88.68	ENST00000646156.1	ENO1 Ensembl NCBI GeneCards UniProt Show fit	enolase 1
chr19_+_13151975 Show fit	88.19	ENST00000588173.1	IER2 Ensembl NCBI GeneCards UniProt Show fit	immediate early response 2
chr11_-_77637751 Show fit	87.78	ENST00000263309.7 ENST00000525064.5	CLNS1A Ensembl NCBI GeneCards UniProt Show fit	chloride nucleotide-sensitive channel 1A
chr3_-_49104745 Show fit	87.76	ENST00000635194.1 ENST00000306125.12 ENST00000634602.1 ENST00000414533.5 ENST00000635443.1 ENST00000452739.5 ENST00000635231.1	QARS1 Ensembl NCBI GeneCards UniProt Show fit	glutaminyl-tRNA synthetase 1
chr11_+_119018746 Show fit	87.72	ENST00000528230.5 ENST00000525303.5 ENST00000434101.6 ENST00000359005.8 ENST00000533632.6 ENST00000533058.5	TRAPPC4 Ensembl NCBI GeneCards UniProt Show fit	trafficking protein particle complex 4
chr1_-_20661356 Show fit	87.55	ENST00000602624.7 ENST00000464364.1	DDOST Ensembl NCBI GeneCards UniProt Show fit	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
chr16_-_11915991 Show fit	87.41	ENST00000420576.6	GSPT1 Ensembl NCBI GeneCards UniProt Show fit	G1 to S phase transition 1
chr1_-_43172504 Show fit	87.20	ENST00000431635.6	EBNA1BP2 Ensembl NCBI GeneCards UniProt Show fit	EBNA1 binding protein 2
chr12_+_69585434 Show fit	87.07	ENST00000299300.11 ENST00000544368.6	CCT2 Ensembl NCBI GeneCards UniProt Show fit	chaperonin containing TCP1 subunit 2
chr4_+_41935423 Show fit	87.07	ENST00000504986.6	TMEM33 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 33
chr1_+_228083061 Show fit	87.00	ENST00000541182.1	ARF1 Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor 1
chr19_-_12669388 Show fit	86.79	ENST00000597961.1 ENST00000598732.1 ENST00000222190.9 ENST00000596731.7	ENSG00000269590.1 Ensembl NCBI GeneCards UniProt Show fit WDR83OS Ensembl NCBI GeneCards UniProt Show fit	novel protein WD repeat domain 83 opposite strand
chr2_+_200889327 Show fit	86.76	ENST00000426253.5 ENST00000454952.1 ENST00000651500.1 ENST00000409020.6 ENST00000359683.8	NIF3L1 Ensembl NCBI GeneCards UniProt Show fit	NGG1 interacting factor 3 like 1
chr19_+_9827886 Show fit	86.56	ENST00000358666.7 ENST00000590068.1 ENST00000593087.1 ENST00000586895.6	UBL5 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin like 5
chr15_-_101294905 Show fit	85.95	ENST00000560496.5	SNRPA1 Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptide A'
chr11_+_66002475 Show fit	85.64	ENST00000312175.7 ENST00000533166.5	BANF1 Ensembl NCBI GeneCards UniProt Show fit	BAF nuclear assembly factor 1
chr12_-_112409305 Show fit	84.97	ENST00000549847.5	RPL6 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L6
chr3_-_150546403 Show fit	84.80	ENST00000239944.7 ENST00000491660.1 ENST00000487153.1	SERP1 Ensembl NCBI GeneCards UniProt Show fit	stress associated endoplasmic reticulum protein 1
chr7_+_5045821 Show fit	84.29	ENST00000353796.7 ENST00000396912.2 ENST00000396904.2	RBAK Ensembl NCBI GeneCards UniProt Show fit RBAK-RBAKDN Ensembl NCBI GeneCards UniProt Show fit	RB associated KRAB zinc finger RBAK-RBAKDN readthrough
chr14_+_57268963 Show fit	84.19	ENST00000261558.8	AP5M1 Ensembl NCBI GeneCards UniProt Show fit	adaptor related protein complex 5 subunit mu 1
chr1_+_112619824 Show fit	84.15	ENST00000263168.4	CAPZA1 Ensembl NCBI GeneCards UniProt Show fit	capping actin protein of muscle Z-line subunit alpha 1
chr1_-_153545793 Show fit	83.63	ENST00000354332.8 ENST00000368716.9	S100A4 Ensembl NCBI GeneCards UniProt Show fit	S100 calcium binding protein A4
chr16_-_85799503 Show fit	83.33	ENST00000253457.8	EMC8 Ensembl NCBI GeneCards UniProt Show fit	ER membrane protein complex subunit 8
chr14_-_21383989 Show fit	83.11	ENST00000216297.7	SUPT16H Ensembl NCBI GeneCards UniProt Show fit	SPT16 homolog, facilitates chromatin remodeling subunit
chr2_-_55269207 Show fit	82.95	ENST00000263629.9 ENST00000403721.5	MTIF2 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial translational initiation factor 2
chr1_-_8878646 Show fit	82.78	ENST00000643438.1	ENO1 Ensembl NCBI GeneCards UniProt Show fit	enolase 1
chr15_-_64989894 Show fit	82.48	ENST00000416889.6 ENST00000204566.7	SPG21 Ensembl NCBI GeneCards UniProt Show fit	SPG21 abhydrolase domain containing, maspardin
chr3_-_49104457 Show fit	82.44	ENST00000635292.1 ENST00000635541.1 ENST00000464962.6	QARS1 Ensembl NCBI GeneCards UniProt Show fit	glutaminyl-tRNA synthetase 1
chr18_+_3262417 Show fit	82.32	ENST00000581193.5 ENST00000400175.9	MYL12B Ensembl NCBI GeneCards UniProt Show fit	myosin light chain 12B
chr7_+_99408958 Show fit	81.56	ENST00000222969.10	BUD31 Ensembl NCBI GeneCards UniProt Show fit	BUD31 homolog
chr16_-_85799554 Show fit	80.76	ENST00000435200.2	EMC8 Ensembl NCBI GeneCards UniProt Show fit	ER membrane protein complex subunit 8
chr15_+_80060113 Show fit	80.60	ENST00000618205.4	ZFAND6 Ensembl NCBI GeneCards UniProt Show fit	zinc finger AN1-type containing 6
chr3_-_146544636 Show fit	80.58	ENST00000486631.5	PLSCR1 Ensembl NCBI GeneCards UniProt Show fit	phospholipid scramblase 1
chr1_+_154974653 Show fit	80.48	ENST00000368439.5	CKS1B Ensembl NCBI GeneCards UniProt Show fit	CDC28 protein kinase regulatory subunit 1B
chr3_-_119677346 Show fit	80.07	ENST00000484810.5 ENST00000497116.1 ENST00000261070.7	COX17 Ensembl NCBI GeneCards UniProt Show fit	cytochrome c oxidase copper chaperone COX17
chr2_+_200889411 Show fit	80.04	ENST00000409357.5 ENST00000409129.2	NIF3L1 Ensembl NCBI GeneCards UniProt Show fit	NGG1 interacting factor 3 like 1
chr19_+_40751179 Show fit	79.77	ENST00000243563.8 ENST00000601393.1	SNRPA Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein polypeptide A
chr19_-_51372640 Show fit	79.61	ENST00000600427.5 ENST00000221978.10	NKG7 Ensembl NCBI GeneCards UniProt Show fit	natural killer cell granule protein 7
chr20_+_408278 Show fit	79.22	ENST00000356286.10 ENST00000382181.2 ENST00000400247.3	RBCK1 Ensembl NCBI GeneCards UniProt Show fit	RANBP2-type and C3HC4-type zinc finger containing 1
chr20_+_35542038 Show fit	79.16	ENST00000357394.8 ENST00000348547.7 ENST00000416206.5 ENST00000640748.1 ENST00000411577.5 ENST00000413587.5	ERGIC3 Ensembl NCBI GeneCards UniProt Show fit	ERGIC and golgi 3
chr6_-_31541937 Show fit	79.15	ENST00000456662.5 ENST00000431908.5 ENST00000456976.5 ENST00000428450.5 ENST00000418897.5 ENST00000396172.6 ENST00000419020.1 ENST00000428098.5	DDX39B Ensembl NCBI GeneCards UniProt Show fit	DExD-box helicase 39B
chrX_+_119468436 Show fit	79.00	ENST00000317881.9	SLC25A5 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 25 member 5
chr6_-_32843994 Show fit	78.89	ENST00000395339.7 ENST00000374882.8	PSMB8 Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit beta 8
chr3_+_160399630 Show fit	78.78	ENST00000465903.5 ENST00000485645.5 ENST00000472991.5 ENST00000467468.5 ENST00000469762.5 ENST00000357388.8 ENST00000489573.5 ENST00000462787.5 ENST00000490207.5 ENST00000485867.5	SMC4 Ensembl NCBI GeneCards UniProt Show fit	structural maintenance of chromosomes 4
chr12_-_389249 Show fit	78.65	ENST00000535014.5 ENST00000543507.1 ENST00000544760.1 ENST00000399788.7	KDM5A Ensembl NCBI GeneCards UniProt Show fit	lysine demethylase 5A
chr17_-_82450693 Show fit	78.48	ENST00000577696.5 ENST00000577471.5 ENST00000582545.2 ENST00000437807.6	CYBC1 Ensembl NCBI GeneCards UniProt Show fit	cytochrome b-245 chaperone 1
chr18_+_21612274 Show fit	78.25	ENST00000579618.1 ENST00000300413.10 ENST00000582475.1	SNRPD1 Ensembl NCBI GeneCards UniProt Show fit	small nuclear ribonucleoprotein D1 polypeptide
chr6_+_30067530 Show fit	78.09	ENST00000376765.6 ENST00000376763.5	PPP1R11 Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory inhibitor subunit 11
chr1_-_3650026 Show fit	78.00	ENST00000424367.5 ENST00000378322.7	WRAP73 Ensembl NCBI GeneCards UniProt Show fit	WD repeat containing, antisense to TP73
chr8_-_67062120 Show fit	77.91	ENST00000357849.9	COPS5 Ensembl NCBI GeneCards UniProt Show fit	COP9 signalosome subunit 5
chr17_+_75012659 Show fit	77.88	ENST00000584208.5 ENST00000301585.10	MRPL58 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L58
chr11_+_75399508 Show fit	77.78	ENST00000531188.6 ENST00000530164.5 ENST00000422465.6 ENST00000278572.10 ENST00000534440.5 ENST00000527446.5 ENST00000526608.5 ENST00000527273.5 ENST00000524851.5	RPS3 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S3
chr1_-_159924529 Show fit	77.77	ENST00000320307.8	TAGLN2 Ensembl NCBI GeneCards UniProt Show fit	transgelin 2
chr13_+_30422487 Show fit	77.15	ENST00000638137.1 ENST00000635918.2	UBE2L5 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 L5
chr19_+_49335396 Show fit	76.99	ENST00000598095.5 ENST00000426897.6 ENST00000323906.9 ENST00000535669.6 ENST00000597602.1 ENST00000595660.1	CD37 Ensembl NCBI GeneCards UniProt Show fit	CD37 molecule
chr11_-_77637776 Show fit	76.75	ENST00000528364.1 ENST00000525428.6 ENST00000532069.5	CLNS1A Ensembl NCBI GeneCards UniProt Show fit	chloride nucleotide-sensitive channel 1A
chr11_+_93784272 Show fit	76.60	ENST00000251871.9 ENST00000639724.1	MED17 Ensembl NCBI GeneCards UniProt Show fit	mediator complex subunit 17
chrX_+_101391202 Show fit	76.49	ENST00000471855.1	RPL36A Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L36a
chr7_-_100100716 Show fit	76.46	ENST00000354230.7 ENST00000425308.5	MCM7 Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 7
chr2_+_197516039 Show fit	75.81	ENST00000448447.6 ENST00000323303.9 ENST00000409360.1	MOB4 Ensembl NCBI GeneCards UniProt Show fit	MOB family member 4, phocein
chr8_-_120445140 Show fit	75.80	ENST00000306185.8	MRPL13 Ensembl NCBI GeneCards UniProt Show fit	mitochondrial ribosomal protein L13
chr1_-_169367746 Show fit	75.80	ENST00000367811.8 ENST00000472647.5	NME7 Ensembl NCBI GeneCards UniProt Show fit	NME/NM23 family member 7
chr13_-_37105664 Show fit	75.76	ENST00000379800.4	CSNK1A1L Ensembl NCBI GeneCards UniProt Show fit	casein kinase 1 alpha 1 like
chr14_+_77708068 Show fit	75.71	ENST00000613856.4	SLIRP Ensembl NCBI GeneCards UniProt Show fit	SRA stem-loop interacting RNA binding protein
chr14_-_69398276 Show fit	75.51	ENST00000557016.6 ENST00000555373.1	ERH Ensembl NCBI GeneCards UniProt Show fit	ERH mRNA splicing and mitosis factor
chr3_-_64023986 Show fit	75.44	ENST00000394431.6	PSMD6 Ensembl NCBI GeneCards UniProt Show fit	proteasome 26S subunit, non-ATPase 6
chr5_-_150449731 Show fit	75.40	ENST00000407193.7	RPS14 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S14
chr20_-_35284745 Show fit	75.34	ENST00000374443.7 ENST00000374450.8	EIF6 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 6
chr11_-_65888435 Show fit	75.14	ENST00000357519.9 ENST00000533045.5 ENST00000338369.6	FIBP Ensembl NCBI GeneCards UniProt Show fit	FGF1 intracellular binding protein
chr11_+_10751203 Show fit	75.14	ENST00000361367.7	CTR9 Ensembl NCBI GeneCards UniProt Show fit	CTR9 homolog, Paf1/RNA polymerase II complex component
chr8_+_144078590 Show fit	75.10	ENST00000525936.1	EXOSC4 Ensembl NCBI GeneCards UniProt Show fit	exosome component 4
chr4_-_10116779 Show fit	75.09	ENST00000499869.7	WDR1 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 1
chr6_-_36547400 Show fit	74.91	ENST00000229812.8	STK38 Ensembl NCBI GeneCards UniProt Show fit	serine/threonine kinase 38
chr14_-_54441325 Show fit	74.47	ENST00000556113.1 ENST00000553660.5 ENST00000216416.9 ENST00000395573.8 ENST00000557690.5	CNIH1 Ensembl NCBI GeneCards UniProt Show fit	cornichon family AMPA receptor auxiliary protein 1
chr1_-_109426410 Show fit	74.27	ENST00000271308.9	PSMA5 Ensembl NCBI GeneCards UniProt Show fit	proteasome 20S subunit alpha 5
chr1_-_43172244 Show fit	74.17	ENST00000236051.3	EBNA1BP2 Ensembl NCBI GeneCards UniProt Show fit	EBNA1 binding protein 2
chr1_-_235161215 Show fit	73.85	ENST00000447801.5 ENST00000408888.8 ENST00000429912.1	RBM34 Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif protein 34
chr19_-_51372686 Show fit	73.77	ENST00000595217.1	NKG7 Ensembl NCBI GeneCards UniProt Show fit	natural killer cell granule protein 7
chrX_+_101390824 Show fit	73.73	ENST00000427805.6 ENST00000614077.4	RPL36A Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein L36a
chr20_-_35284715 Show fit	73.66	ENST00000374436.7 ENST00000675032.1	EIF6 Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 6
chr14_-_100376251 Show fit	73.29	ENST00000556645.5 ENST00000556209.5 ENST00000556504.5 ENST00000556435.5 ENST00000554772.5 ENST00000553581.1 ENST00000553769.6 ENST00000554605.5 ENST00000557722.5 ENST00000553413.5 ENST00000553524.5 ENST00000358655.8	WARS1 Ensembl NCBI GeneCards UniProt Show fit	tryptophanyl-tRNA synthetase 1
chr15_-_84716063 Show fit	72.99	ENST00000558217.5 ENST00000558196.1 ENST00000558134.5	SEC11A Ensembl NCBI GeneCards UniProt Show fit	SEC11 homolog A, signal peptidase complex subunit
chr4_+_41935114 Show fit	72.92	ENST00000508448.5 ENST00000513702.5 ENST00000325094.9	TMEM33 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 33
chr11_+_118359572 Show fit	72.84	ENST00000252108.8 ENST00000431736.6	UBE4A Ensembl NCBI GeneCards UniProt Show fit	ubiquitination factor E4A
chr7_+_2242256 Show fit	72.55	ENST00000397046.5 ENST00000397048.5 ENST00000454650.1	NUDT1 Ensembl NCBI GeneCards UniProt Show fit	nudix hydrolase 1
chr5_+_69234795 Show fit	72.42	ENST00000626796.2 ENST00000629350.2 ENST00000506563.5 ENST00000256443.8 ENST00000514676.5	CDK7 Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase 7
chr5_-_140691312 Show fit	72.40	ENST00000438307.6 ENST00000415192.6 ENST00000509087.2 ENST00000675698.1 ENST00000504156.7 ENST00000457527.6 ENST00000307633.7 ENST00000676327.1 ENST00000675851.1 ENST00000675366.1 ENST00000675204.1 ENST00000507746.7 ENST00000431330.7	HARS1 Ensembl NCBI GeneCards UniProt Show fit	histidyl-tRNA synthetase 1
chr16_-_29454347 Show fit	72.28	ENST00000569622.5	BOLA2-SMG1P6 Ensembl NCBI GeneCards UniProt Show fit	BOLA2-SMG1P6 readthrough
chr4_-_102828022 Show fit	71.96	ENST00000502690.5	UBE2D3 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin conjugating enzyme E2 D3
chr8_+_144358557 Show fit	71.68	ENST00000530047.5 ENST00000527078.6 ENST00000674870.1 ENST00000526338.7 ENST00000402965.5 ENST00000329994.7 ENST00000526752.3 ENST00000533662.2 ENST00000534725.6 ENST00000674929.1 ENST00000675597.1 ENST00000643944.2 ENST00000675121.1	SLC52A2 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 52 member 2
chr12_+_95474081 Show fit	71.59	ENST00000546753.5	METAP2 Ensembl NCBI GeneCards UniProt Show fit	methionyl aminopeptidase 2
chr1_-_20661518 Show fit	71.27	ENST00000415136.6	DDOST Ensembl NCBI GeneCards UniProt Show fit	dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
chr9_+_113275642 Show fit	71.14	ENST00000374199.9 ENST00000374198.5	PRPF4 Ensembl NCBI GeneCards UniProt Show fit	pre-mRNA processing factor 4
chr15_-_84716099 Show fit	71.06	ENST00000560266.5	SEC11A Ensembl NCBI GeneCards UniProt Show fit	SEC11 homolog A, signal peptidase complex subunit
chr19_+_7637099 Show fit	70.97	ENST00000595950.5 ENST00000221283.10 ENST00000441779.6 ENST00000414284.6	STXBP2 Ensembl NCBI GeneCards UniProt Show fit	syntaxin binding protein 2
chrX_+_120604199 Show fit	70.95	ENST00000371315.3	MCTS1 Ensembl NCBI GeneCards UniProt Show fit	MCTS1 re-initiation and release factor
chr10_+_73744346 Show fit	70.84	ENST00000345254.9 ENST00000339365.2	SEC24C Ensembl NCBI GeneCards UniProt Show fit	SEC24 homolog C, COPII coat complex component
chr1_+_16440700 Show fit	70.82	ENST00000504551.6 ENST00000457722.6 ENST00000337132.10 ENST00000443980.6	NECAP2 Ensembl NCBI GeneCards UniProt Show fit	NECAP endocytosis associated 2
chr17_-_48944772 Show fit	70.80	ENST00000290330.7 ENST00000502492.6	SNF8 Ensembl NCBI GeneCards UniProt Show fit	SNF8 subunit of ESCRT-II

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
95.5	286.4	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
92.0	275.9	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
84.7	508.2	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
69.0	207.1	GO:0090149	mitochondrial membrane fission(GO:0090149)
68.9	206.7	GO:0044878	mitotic cytokinesis checkpoint(GO:0044878)
61.6	246.5	GO:0036496	regulation of translational initiation by eIF2 alpha dephosphorylation(GO:0036496)
51.0	255.2	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
49.8	149.5	GO:1903722	regulation of centriole elongation(GO:1903722)
48.5	194.1	GO:0016334	morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
47.5	47.5	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
47.3	142.0	GO:0097212	lysosomal membrane organization(GO:0097212) regulation of late endosome to lysosome transport(GO:1902822)
45.7	137.2	GO:0070476	RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
45.6	227.8	GO:0019348	dolichol metabolic process(GO:0019348)
45.2	316.6	GO:1901315	negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
44.8	134.3	GO:0000454	snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
43.9	131.8	GO:0002188	translation reinitiation(GO:0002188)
43.6	130.9	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
43.6	87.2	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
41.9	251.6	GO:0000973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
40.7	122.0	GO:0046586	regulation of calcium-dependent cell-cell adhesion(GO:0046586)
40.5	162.2	GO:0032240	negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
40.5	161.9	GO:0018106	peptidyl-histidine phosphorylation(GO:0018106)
40.4	121.3	GO:0002184	cytoplasmic translational termination(GO:0002184)
40.2	120.7	GO:1901860	positive regulation of mitochondrial DNA metabolic process(GO:1901860)
39.5	158.2	GO:0000961	negative regulation of mitochondrial RNA catabolic process(GO:0000961)
39.3	39.3	GO:0009838	abscission(GO:0009838)
38.6	308.5	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
38.1	38.1	GO:0098507	polynucleotide 5' dephosphorylation(GO:0098507)
37.9	37.9	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
37.6	150.5	GO:0010796	regulation of multivesicular body size(GO:0010796)
37.0	148.1	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
36.4	109.3	GO:1902524	positive regulation of protein K48-linked ubiquitination(GO:1902524)
35.7	178.4	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
35.4	106.1	GO:2001166	regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
35.0	210.0	GO:0075525	viral translational termination-reinitiation(GO:0075525)
34.7	104.2	GO:0030327	prenylated protein catabolic process(GO:0030327)
34.6	241.9	GO:0032218	riboflavin transport(GO:0032218)
34.1	102.4	GO:0044837	assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
33.2	232.7	GO:1902527	positive regulation of protein monoubiquitination(GO:1902527)
32.3	97.0	GO:1904732	regulation of electron carrier activity(GO:1904732)
32.1	32.1	GO:0046070	dGTP metabolic process(GO:0046070)
31.8	222.7	GO:0007144	female meiosis I(GO:0007144)
31.6	221.2	GO:0006983	ER overload response(GO:0006983)
31.3	313.0	GO:0009146	purine nucleoside triphosphate catabolic process(GO:0009146)
31.2	187.4	GO:1903677	regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
30.9	123.5	GO:0002270	plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
30.8	92.5	GO:0071461	cellular response to redox state(GO:0071461)
30.7	92.0	GO:1903595	positive regulation of histamine secretion by mast cell(GO:1903595)
30.3	91.0	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
30.2	181.4	GO:0009212	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
29.3	117.3	GO:0043985	histone H4-R3 methylation(GO:0043985)
28.4	170.2	GO:0006051	mannosamine metabolic process(GO:0006050) N-acetylmannosamine metabolic process(GO:0006051)
27.7	194.0	GO:1904431	positive regulation of t-circle formation(GO:1904431)
27.5	110.1	GO:2000434	regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
27.4	109.7	GO:0046116	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
27.2	1141.4	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
27.1	135.3	GO:1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
26.9	80.6	GO:0070901	mitochondrial tRNA methylation(GO:0070901)
26.5	79.5	GO:0071816	tail-anchored membrane protein insertion into ER membrane(GO:0071816)
26.4	105.5	GO:1902544	regulation of DNA N-glycosylase activity(GO:1902544)
26.3	210.6	GO:0034982	mitochondrial protein processing(GO:0034982)
26.3	78.8	GO:0097698	telomere maintenance via base-excision repair(GO:0097698)
25.9	77.6	GO:0035752	lysosomal lumen pH elevation(GO:0035752)
25.6	128.0	GO:2000210	positive regulation of anoikis(GO:2000210)
25.6	25.6	GO:2000653	regulation of genetic imprinting(GO:2000653)
25.6	128.0	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
25.4	101.4	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
24.9	2690.1	GO:0051436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051436)
24.9	74.7	GO:0016074	snoRNA metabolic process(GO:0016074)
24.6	271.1	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
24.3	194.4	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
24.2	24.2	GO:0045048	protein insertion into ER membrane(GO:0045048)
24.1	120.6	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
24.0	673.1	GO:0070979	protein K11-linked ubiquitination(GO:0070979)
23.9	95.5	GO:0002084	protein depalmitoylation(GO:0002084)
23.6	70.8	GO:0001188	RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
23.6	165.2	GO:0006616	SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
23.5	234.9	GO:2000002	negative regulation of DNA damage checkpoint(GO:2000002)
23.0	506.5	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
22.5	67.6	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
22.4	112.0	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
22.3	155.8	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
22.2	111.1	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
21.8	65.5	GO:0051182	coenzyme transport(GO:0051182)
21.5	301.0	GO:0051096	positive regulation of helicase activity(GO:0051096)
21.5	64.4	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
21.4	42.8	GO:0071033	nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
21.2	42.4	GO:1904844	response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
20.5	451.2	GO:0000028	ribosomal small subunit assembly(GO:0000028)
20.5	102.4	GO:0035521	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
20.4	142.9	GO:0015866	ADP transport(GO:0015866)
20.3	223.0	GO:1903944	regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
20.1	80.4	GO:0031064	negative regulation of histone deacetylation(GO:0031064)
20.1	140.6	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
20.0	621.5	GO:0000460	maturation of 5.8S rRNA(GO:0000460)
19.9	59.6	GO:0046081	dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
19.7	59.1	GO:0090669	telomerase RNA stabilization(GO:0090669)
19.6	58.8	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
19.3	57.9	GO:1902568	positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
19.2	134.5	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
19.1	38.3	GO:0045903	positive regulation of translational fidelity(GO:0045903)
18.8	56.5	GO:1990022	RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
18.7	56.2	GO:0070902	mitochondrial tRNA pseudouridine synthesis(GO:0070902)
18.7	56.2	GO:0042946	glucoside transport(GO:0042946)
18.6	37.2	GO:1903179	regulation of dopamine biosynthetic process(GO:1903179) positive regulation of dopamine biosynthetic process(GO:1903181)
18.6	55.7	GO:0036089	cleavage furrow formation(GO:0036089)
18.2	127.4	GO:1903895	negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
18.1	235.5	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
17.9	143.1	GO:0007008	outer mitochondrial membrane organization(GO:0007008)
17.9	53.6	GO:0014810	positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014810)
17.7	71.0	GO:0039516	modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
17.7	70.9	GO:0043335	protein unfolding(GO:0043335)
17.7	53.1	GO:0033512	L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
17.6	52.8	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
17.6	70.3	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
17.4	69.8	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
17.4	104.2	GO:0010032	meiotic chromosome condensation(GO:0010032)
17.2	137.9	GO:1904851	positive regulation of establishment of protein localization to telomere(GO:1904851)
17.2	68.8	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
17.1	102.5	GO:1900368	adenosine to inosine editing(GO:0006382) regulation of RNA interference(GO:1900368) negative regulation of RNA interference(GO:1900369)
16.8	84.2	GO:0006740	NADPH regeneration(GO:0006740)
16.6	83.1	GO:0072402	response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423)
16.5	330.2	GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
16.5	132.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
16.5	65.8	GO:0046833	positive regulation of RNA export from nucleus(GO:0046833)
16.4	376.8	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
16.3	48.9	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
16.3	48.9	GO:1902905	positive regulation of fibril organization(GO:1902905)
16.1	112.7	GO:0015846	polyamine transport(GO:0015846)
16.1	16.1	GO:0033206	meiotic cytokinesis(GO:0033206)
16.0	144.1	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
16.0	1150.7	GO:0070125	mitochondrial translational elongation(GO:0070125)
16.0	63.9	GO:0016240	autophagosome docking(GO:0016240)
15.9	47.7	GO:0000738	DNA catabolic process, exonucleolytic(GO:0000738)
15.9	31.8	GO:0008611	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
15.8	142.5	GO:0006167	AMP biosynthetic process(GO:0006167)
15.7	31.4	GO:0000469	cleavage involved in rRNA processing(GO:0000469)
15.7	344.9	GO:0006293	nucleotide-excision repair, preincision complex stabilization(GO:0006293)
15.7	62.7	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
15.7	47.0	GO:0006226	dUMP biosynthetic process(GO:0006226)
15.6	2000.6	GO:0045047	protein targeting to ER(GO:0045047)
15.6	78.1	GO:0044806	G-quadruplex DNA unwinding(GO:0044806)
15.6	62.4	GO:0032079	positive regulation of endodeoxyribonuclease activity(GO:0032079)
15.6	171.3	GO:0000920	cell separation after cytokinesis(GO:0000920)
15.6	31.1	GO:0080154	regulation of fertilization(GO:0080154)
15.4	138.8	GO:0038110	interleukin-2-mediated signaling pathway(GO:0038110)
15.4	77.0	GO:0030242	pexophagy(GO:0030242)
15.3	214.4	GO:1900363	regulation of mRNA polyadenylation(GO:1900363)
15.3	627.1	GO:0009452	7-methylguanosine mRNA capping(GO:0006370) 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
15.3	122.1	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
15.2	259.0	GO:0060546	negative regulation of necroptotic process(GO:0060546)
15.1	45.2	GO:0036388	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
15.0	165.3	GO:0015939	pantothenate metabolic process(GO:0015939)
14.9	59.6	GO:1903758	regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
14.9	89.3	GO:0006696	ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
14.8	29.7	GO:1904751	positive regulation of protein localization to nucleolus(GO:1904751)
14.7	44.0	GO:2000687	negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
14.6	131.7	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
14.6	58.5	GO:0044210	'de novo' CTP biosynthetic process(GO:0044210)
14.6	160.6	GO:2000680	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
14.4	201.7	GO:0001682	tRNA 5'-leader removal(GO:0001682)
14.4	71.9	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
14.4	86.3	GO:0051708	intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
14.2	42.5	GO:0070863	positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
14.1	70.5	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
14.1	28.2	GO:0018312	peptidyl-serine ADP-ribosylation(GO:0018312)
13.9	13.9	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle(GO:0051439)
13.9	554.6	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
13.8	55.2	GO:0070370	heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
13.7	109.8	GO:1903894	regulation of IRE1-mediated unfolded protein response(GO:1903894)
13.6	136.3	GO:0002183	cytoplasmic translational initiation(GO:0002183)
13.6	54.3	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
13.5	54.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
13.5	67.5	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
13.5	53.9	GO:0033314	mitotic DNA replication checkpoint(GO:0033314)
13.5	80.8	GO:0043248	proteasome assembly(GO:0043248)
13.4	67.1	GO:0090135	actin filament branching(GO:0090135)
13.3	13.3	GO:1902594	viral penetration into host nucleus(GO:0075732) multi-organism nuclear import(GO:1902594)
13.3	79.5	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
13.2	39.7	GO:0070662	mast cell proliferation(GO:0070662)
13.2	13.2	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
13.2	289.3	GO:0043101	purine-containing compound salvage(GO:0043101)
13.1	118.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
13.1	91.6	GO:0008215	spermine metabolic process(GO:0008215)
13.0	13.0	GO:0019081	viral translation(GO:0019081)
13.0	64.8	GO:0090168	Golgi reassembly(GO:0090168)
12.9	38.8	GO:0046292	formaldehyde metabolic process(GO:0046292)
12.8	63.8	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
12.7	38.0	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
12.6	37.7	GO:1905000	regulation of membrane repolarization during atrial cardiac muscle cell action potential(GO:1905000)
12.5	37.6	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
12.5	37.5	GO:1901355	response to rapamycin(GO:1901355)
12.5	37.5	GO:0070510	regulation of histone H4-K20 methylation(GO:0070510) positive regulation of histone H4-K20 methylation(GO:0070512)
12.4	149.0	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
12.4	74.4	GO:1904016	response to Thyroglobulin triiodothyronine(GO:1904016)
12.4	12.4	GO:1900060	negative regulation of sphingolipid biosynthetic process(GO:0090155) negative regulation of ceramide biosynthetic process(GO:1900060)
12.3	36.8	GO:0034124	regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
12.2	48.8	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
12.2	24.3	GO:1902965	regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
12.1	241.9	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802)
12.0	12.0	GO:0019918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
12.0	72.0	GO:0032511	late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
11.9	11.9	GO:1903094	regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
11.9	119.1	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
11.8	47.4	GO:0018201	N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
11.8	47.2	GO:1901873	regulation of post-translational protein modification(GO:1901873)
11.8	58.8	GO:0071169	establishment of protein localization to chromatin(GO:0071169)
11.7	70.4	GO:2000301	negative regulation of synaptic vesicle exocytosis(GO:2000301)
11.7	58.6	GO:1902044	regulation of Fas signaling pathway(GO:1902044)
11.7	163.6	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
11.6	150.9	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
11.6	185.0	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
11.4	22.9	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
11.4	68.6	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
11.4	914.4	GO:0071349	interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
11.4	91.3	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
11.4	34.2	GO:0019087	transformation of host cell by virus(GO:0019087)
11.4	11.4	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
11.3	102.0	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
11.3	11.3	GO:0010482	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
11.2	67.4	GO:0032487	regulation of Rap protein signal transduction(GO:0032487)
11.2	100.8	GO:0045835	negative regulation of meiotic nuclear division(GO:0045835)
11.2	167.8	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
11.2	100.6	GO:0035437	protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
11.2	78.2	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
11.2	55.8	GO:0071894	histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
11.1	276.8	GO:0006465	signal peptide processing(GO:0006465)
11.1	44.2	GO:0008295	spermidine biosynthetic process(GO:0008295)
10.9	43.5	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
10.8	130.0	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
10.8	21.7	GO:0072321	chaperone-mediated protein transport(GO:0072321)
10.8	21.6	GO:0046984	regulation of hemoglobin biosynthetic process(GO:0046984)
10.6	106.4	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
10.6	21.2	GO:0009826	unidimensional cell growth(GO:0009826)
10.5	42.0	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
10.4	51.8	GO:1904424	regulation of GTP binding(GO:1904424)
10.3	51.7	GO:2001107	negative regulation of establishment of T cell polarity(GO:1903904) negative regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001107)
10.3	113.6	GO:0060753	regulation of mast cell chemotaxis(GO:0060753)
10.3	30.9	GO:1903031	regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) positive regulation of microtubule binding(GO:1904528)
10.3	82.0	GO:0034625	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
10.2	40.7	GO:0002277	myeloid dendritic cell activation involved in immune response(GO:0002277)
10.2	61.0	GO:0071460	cellular response to cell-matrix adhesion(GO:0071460)
10.1	91.1	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
10.1	141.6	GO:0018206	peptidyl-methionine modification(GO:0018206)
10.1	40.3	GO:1900127	positive regulation of hyaluronan biosynthetic process(GO:1900127)
10.1	30.2	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
10.0	40.2	GO:0030037	actin filament reorganization involved in cell cycle(GO:0030037)
10.0	30.1	GO:0042727	flavin-containing compound biosynthetic process(GO:0042727)
10.0	150.2	GO:0016180	snRNA processing(GO:0016180)
10.0	29.9	GO:0030047	actin modification(GO:0030047)
9.9	29.6	GO:0030961	peptidyl-arginine hydroxylation(GO:0030961)
9.9	29.6	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
9.8	49.2	GO:1903593	regulation of histamine secretion by mast cell(GO:1903593)
9.8	19.6	GO:0009211	pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
9.8	19.6	GO:0045091	single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692) regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091)
9.8	29.4	GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
9.8	39.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
9.7	38.9	GO:0002290	gamma-delta T cell activation involved in immune response(GO:0002290) negative regulation of interferon-beta secretion(GO:0035548) regulation of gamma-delta T cell activation involved in immune response(GO:2001191) positive regulation of gamma-delta T cell activation involved in immune response(GO:2001193)
9.7	38.7	GO:0032747	positive regulation of interleukin-23 production(GO:0032747)
9.7	29.0	GO:0051793	medium-chain fatty acid catabolic process(GO:0051793)
9.6	28.8	GO:2000174	regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
9.6	57.5	GO:0089700	protein kinase D signaling(GO:0089700)
9.5	161.9	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
9.5	95.0	GO:0045116	protein neddylation(GO:0045116)
9.5	104.0	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
9.4	225.0	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
9.4	46.8	GO:0034134	toll-like receptor 2 signaling pathway(GO:0034134)
9.3	74.4	GO:0045176	apical protein localization(GO:0045176)
9.3	27.8	GO:1905216	positive regulation of RNA binding(GO:1905216)
9.3	656.9	GO:0032981	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
9.2	46.2	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
9.1	128.0	GO:0000338	protein deneddylation(GO:0000338)
9.1	18.1	GO:0002901	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
9.0	45.2	GO:0051792	medium-chain fatty acid biosynthetic process(GO:0051792)
9.0	180.9	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
9.0	27.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
9.0	36.0	GO:0070433	negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
9.0	18.0	GO:0051177	meiotic sister chromatid cohesion(GO:0051177)
9.0	54.0	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
9.0	26.9	GO:1901389	regulation of transforming growth factor beta activation(GO:1901388) negative regulation of transforming growth factor beta activation(GO:1901389)
8.9	35.8	GO:0048200	COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
8.9	44.6	GO:0045337	geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
8.9	8.9	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
8.8	114.5	GO:0006228	UTP biosynthetic process(GO:0006228)
8.8	131.8	GO:0006221	pyrimidine nucleotide biosynthetic process(GO:0006221)
8.8	26.3	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
8.8	52.6	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
8.8	26.3	GO:0009106	lipoate metabolic process(GO:0009106)
8.7	69.8	GO:0042407	cristae formation(GO:0042407)
8.7	43.5	GO:0090385	phagosome-lysosome fusion(GO:0090385)
8.7	43.4	GO:0002176	male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
8.6	43.0	GO:0035234	ectopic germ cell programmed cell death(GO:0035234)
8.5	17.1	GO:0033182	regulation of histone ubiquitination(GO:0033182)
8.5	663.3	GO:0045454	cell redox homeostasis(GO:0045454)
8.5	280.5	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
8.5	59.4	GO:0071475	cellular hyperosmotic salinity response(GO:0071475)
8.5	42.3	GO:1900086	regulation of peptidyl-tyrosine autophosphorylation(GO:1900084) positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
8.4	25.3	GO:0045588	positive regulation of gamma-delta T cell differentiation(GO:0045588)
8.4	33.7	GO:1903182	regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
8.4	16.8	GO:0070269	pyroptosis(GO:0070269)
8.3	50.1	GO:1903376	neuron intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0036480) regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903376)
8.3	25.0	GO:0006781	succinyl-CoA pathway(GO:0006781)
8.3	74.8	GO:0006528	asparagine metabolic process(GO:0006528)
8.3	249.3	GO:0006337	nucleosome disassembly(GO:0006337)
8.2	24.7	GO:1904457	glucosylceramide catabolic process(GO:0006680) beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457)
8.2	32.9	GO:1904977	lymphatic endothelial cell migration(GO:1904977)
8.2	24.7	GO:0035048	splicing factor protein import into nucleus(GO:0035048)
8.2	57.4	GO:1990564	protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
8.2	16.4	GO:0009133	ADP biosynthetic process(GO:0006172) nucleoside diphosphate biosynthetic process(GO:0009133) purine nucleoside diphosphate biosynthetic process(GO:0009136) purine ribonucleoside diphosphate biosynthetic process(GO:0009180) ribonucleoside diphosphate biosynthetic process(GO:0009188)
8.2	32.7	GO:0022417	protein maturation by protein folding(GO:0022417)
8.2	16.3	GO:0002424	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
8.2	40.8	GO:1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
8.1	583.8	GO:0048208	vesicle coating(GO:0006901) vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
8.1	8.1	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
8.0	8.0	GO:0032831	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
8.0	23.9	GO:0001887	selenium compound metabolic process(GO:0001887)
8.0	47.8	GO:2000825	positive regulation of androgen receptor activity(GO:2000825)
7.8	39.2	GO:0031536	positive regulation of exit from mitosis(GO:0031536)
7.8	15.5	GO:0010040	response to iron(II) ion(GO:0010040)
7.6	30.6	GO:0043366	beta selection(GO:0043366)
7.6	22.9	GO:0036111	very long-chain fatty-acyl-CoA metabolic process(GO:0036111)
7.6	38.1	GO:0051643	endoplasmic reticulum localization(GO:0051643)
7.6	53.3	GO:0044387	negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
7.6	68.5	GO:0051001	negative regulation of nitric-oxide synthase activity(GO:0051001)
7.6	30.4	GO:0000451	rRNA 2'-O-methylation(GO:0000451)
7.6	22.8	GO:0031145	anaphase-promoting complex-dependent catabolic process(GO:0031145)
7.6	22.8	GO:0045897	positive regulation of transcription during mitosis(GO:0045897)
7.6	68.1	GO:0006335	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
7.5	60.0	GO:0021943	formation of radial glial scaffolds(GO:0021943)
7.5	37.5	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
7.5	59.9	GO:0051026	chiasma assembly(GO:0051026)
7.4	14.9	GO:0042255	ribosome assembly(GO:0042255)
7.4	118.9	GO:0044818	mitotic G2/M transition checkpoint(GO:0044818)
7.3	95.1	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
7.3	21.9	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
7.3	72.8	GO:0045292	mRNA cis splicing, via spliceosome(GO:0045292)
7.3	36.3	GO:1901838	regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836) positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
7.2	231.9	GO:0033120	positive regulation of RNA splicing(GO:0033120)
7.2	94.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
7.2	35.9	GO:0015862	uridine transport(GO:0015862)
7.2	79.0	GO:0019388	galactose catabolic process(GO:0019388)
7.2	7.2	GO:1903630	regulation of aminoacyl-tRNA ligase activity(GO:1903630)
7.2	57.2	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
7.1	49.8	GO:0032075	positive regulation of nuclease activity(GO:0032075)
7.1	77.8	GO:0050690	regulation of defense response to virus by virus(GO:0050690)
7.1	7.1	GO:0060623	regulation of chromosome condensation(GO:0060623)
7.0	7.0	GO:0034427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'(GO:0034427)
7.0	63.3	GO:0070141	response to UV-A(GO:0070141) cellular response to UV-A(GO:0071492)
7.0	35.0	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
7.0	62.9	GO:0090435	protein localization to nuclear envelope(GO:0090435)
7.0	48.9	GO:0072718	response to cisplatin(GO:0072718)
7.0	132.4	GO:0050434	positive regulation of viral transcription(GO:0050434)
6.9	110.1	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
6.9	68.7	GO:0045651	positive regulation of macrophage differentiation(GO:0045651)
6.9	27.4	GO:0034670	chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
6.8	34.1	GO:0070836	caveola assembly(GO:0070836)
6.8	40.7	GO:0090161	Golgi ribbon formation(GO:0090161)
6.8	202.7	GO:0006625	protein targeting to peroxisome(GO:0006625) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
6.7	6.7	GO:0046368	GDP-L-fucose metabolic process(GO:0046368)
6.7	26.7	GO:1904504	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
6.6	86.4	GO:0010528	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
6.6	19.9	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
6.6	79.3	GO:0035458	cellular response to interferon-beta(GO:0035458)
6.6	26.4	GO:1903527	positive regulation of membrane tubulation(GO:1903527)
6.5	13.1	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
6.5	437.9	GO:0045071	negative regulation of viral genome replication(GO:0045071)
6.5	32.6	GO:0046719	regulation by virus of viral protein levels in host cell(GO:0046719) positive regulation by virus of viral protein levels in host cell(GO:0046726)
6.5	19.5	GO:0038156	interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
6.5	64.8	GO:0051601	exocyst localization(GO:0051601)
6.5	103.3	GO:0006415	translational termination(GO:0006415)
6.4	32.2	GO:2000035	regulation of stem cell division(GO:2000035)
6.4	32.2	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
6.4	38.4	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
6.4	19.1	GO:0060544	regulation of necroptotic process(GO:0060544)
6.4	19.1	GO:0006121	mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
6.4	44.5	GO:0032506	cytokinetic process(GO:0032506)
6.3	126.3	GO:0045948	positive regulation of translational initiation(GO:0045948)
6.3	12.6	GO:0031393	negative regulation of prostaglandin biosynthetic process(GO:0031393)
6.2	24.9	GO:0090670	RNA localization to Cajal body(GO:0090670) telomerase RNA localization to Cajal body(GO:0090671) telomerase RNA localization(GO:0090672) regulation of telomerase RNA localization to Cajal body(GO:1904872)
6.2	18.6	GO:2000298	regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
6.2	18.6	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
6.2	12.4	GO:0033523	histone H2B ubiquitination(GO:0033523)
6.2	24.7	GO:0009440	cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
6.2	18.5	GO:0003162	atrioventricular node development(GO:0003162)
6.2	239.9	GO:0034314	Arp2/3 complex-mediated actin nucleation(GO:0034314)
6.1	12.2	GO:0001923	B-1 B cell differentiation(GO:0001923)
6.1	6.1	GO:1901739	regulation of myoblast fusion(GO:1901739)
6.0	12.1	GO:0035511	oxidative DNA demethylation(GO:0035511)
6.0	24.0	GO:0050917	sensory perception of umami taste(GO:0050917)
6.0	18.0	GO:0045876	positive regulation of sister chromatid cohesion(GO:0045876)
6.0	23.9	GO:0009438	methylglyoxal metabolic process(GO:0009438)
6.0	23.8	GO:1902262	apoptotic process involved in patterning of blood vessels(GO:1902262)
5.9	398.2	GO:0006413	translational initiation(GO:0006413)
5.9	41.4	GO:0045716	positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
5.9	5.9	GO:0035574	histone H4-K20 demethylation(GO:0035574)
5.9	112.0	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
5.8	29.2	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
5.8	46.5	GO:1902033	regulation of hematopoietic stem cell proliferation(GO:1902033) positive regulation of hematopoietic stem cell proliferation(GO:1902035)
5.8	17.4	GO:1904715	negative regulation of chaperone-mediated autophagy(GO:1904715)
5.8	11.6	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
5.8	17.3	GO:1902766	skeletal muscle satellite cell migration(GO:1902766)
5.7	17.2	GO:0002296	T-helper 1 cell lineage commitment(GO:0002296)
5.7	34.4	GO:0006021	inositol biosynthetic process(GO:0006021)
5.7	5.7	GO:0002513	tolerance induction to self antigen(GO:0002513)
5.7	34.3	GO:0039526	suppression by virus of host apoptotic process(GO:0019050) modulation by virus of host apoptotic process(GO:0039526)
5.6	39.4	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
5.6	16.8	GO:0002349	histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
5.6	151.3	GO:0006515	misfolded or incompletely synthesized protein catabolic process(GO:0006515)
5.6	95.2	GO:0002523	leukocyte migration involved in inflammatory response(GO:0002523)
5.6	72.8	GO:0098969	neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
5.6	16.8	GO:0002774	Fc receptor mediated inhibitory signaling pathway(GO:0002774)
5.6	50.3	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
5.6	1565.2	GO:0000375	RNA splicing, via transesterification reactions(GO:0000375)
5.6	22.3	GO:0042450	arginine biosynthetic process via ornithine(GO:0042450)
5.5	27.7	GO:2000645	regulation of receptor catabolic process(GO:2000644) negative regulation of receptor catabolic process(GO:2000645)
5.5	160.4	GO:0006119	oxidative phosphorylation(GO:0006119)
5.5	16.5	GO:0051684	maintenance of Golgi location(GO:0051684)
5.5	21.8	GO:0030200	heparan sulfate proteoglycan catabolic process(GO:0030200)
5.4	37.9	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
5.4	48.3	GO:0018344	protein geranylgeranylation(GO:0018344)
5.4	32.2	GO:0072553	terminal button organization(GO:0072553)
5.4	16.1	GO:0007549	dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
5.4	16.1	GO:0036233	glycine import(GO:0036233)
5.3	101.6	GO:0032515	negative regulation of phosphoprotein phosphatase activity(GO:0032515)
5.3	26.7	GO:0016080	synaptic vesicle targeting(GO:0016080)
5.3	53.3	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
5.3	21.3	GO:1902963	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
5.3	16.0	GO:0042939	glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
5.3	21.3	GO:0003409	optic cup structural organization(GO:0003409)
5.3	15.9	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
5.3	36.8	GO:0051013	microtubule severing(GO:0051013)
5.2	5.2	GO:0006409	tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
5.2	57.1	GO:0070911	global genome nucleotide-excision repair(GO:0070911)
5.2	10.4	GO:0034769	basement membrane disassembly(GO:0034769)
5.2	5.2	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
5.1	20.5	GO:0000076	DNA replication checkpoint(GO:0000076)
5.1	10.2	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
5.1	25.5	GO:0046618	drug export(GO:0046618)
5.1	10.2	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
5.1	15.2	GO:2000798	amniotic stem cell differentiation(GO:0097086) negative regulation of dense core granule biogenesis(GO:2000706) negative regulation of mesenchymal stem cell differentiation(GO:2000740) regulation of amniotic stem cell differentiation(GO:2000797) negative regulation of amniotic stem cell differentiation(GO:2000798)
5.1	10.1	GO:0014900	regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
5.0	70.5	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
5.0	39.8	GO:0010579	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
5.0	14.9	GO:0071500	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) cellular response to nitrosative stress(GO:0071500)
5.0	94.2	GO:0070536	protein K63-linked deubiquitination(GO:0070536)
4.9	24.7	GO:0050713	negative regulation of interleukin-1 beta secretion(GO:0050713)
4.9	188.0	GO:0007077	mitotic nuclear envelope disassembly(GO:0007077)
4.9	24.7	GO:0032380	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
4.9	9.9	GO:0006344	maintenance of chromatin silencing(GO:0006344)
4.9	39.4	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
4.9	9.8	GO:0061043	regulation of vascular wound healing(GO:0061043)
4.9	4.9	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
4.9	4.9	GO:0045410	positive regulation of interleukin-6 biosynthetic process(GO:0045410)
4.9	53.5	GO:0006903	vesicle targeting(GO:0006903)
4.8	115.7	GO:0016578	histone deubiquitination(GO:0016578)
4.8	38.5	GO:0051016	barbed-end actin filament capping(GO:0051016)
4.8	9.6	GO:0032632	tolerance induction dependent upon immune response(GO:0002461) interleukin-3 production(GO:0032632) regulation of interleukin-3 production(GO:0032672)
4.8	9.6	GO:2000812	regulation of barbed-end actin filament capping(GO:2000812)
4.8	14.3	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
4.8	9.5	GO:0035261	external genitalia morphogenesis(GO:0035261)
4.8	19.0	GO:0046900	tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
4.8	52.3	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
4.7	37.9	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
4.7	221.5	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
4.7	141.3	GO:0090383	phagosome acidification(GO:0090383)
4.7	112.6	GO:0000185	activation of MAPKKK activity(GO:0000185)
4.7	28.1	GO:0032460	negative regulation of protein oligomerization(GO:0032460)
4.7	18.7	GO:2000196	positive regulation of female gonad development(GO:2000196)
4.6	18.6	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
4.6	55.6	GO:0014870	response to muscle inactivity(GO:0014870)
4.6	32.4	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
4.6	9.2	GO:0031935	regulation of chromatin silencing(GO:0031935)
4.6	55.1	GO:0017121	phospholipid scrambling(GO:0017121)
4.6	105.3	GO:0043968	histone H2A acetylation(GO:0043968)
4.6	13.7	GO:0070475	rRNA base methylation(GO:0070475)
4.5	9.1	GO:1901253	regulation of intracellular transport of viral material(GO:1901252) negative regulation of intracellular transport of viral material(GO:1901253)
4.5	36.1	GO:0009113	purine nucleobase biosynthetic process(GO:0009113)
4.5	31.3	GO:0042797	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
4.4	13.3	GO:0015822	ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
4.4	13.3	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
4.4	17.7	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
4.4	8.8	GO:0046349	amino sugar biosynthetic process(GO:0046349)
4.4	39.6	GO:0001765	membrane raft assembly(GO:0001765)
4.4	30.7	GO:0071340	skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
4.4	13.1	GO:0045658	regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
4.4	21.8	GO:1990253	cellular response to leucine starvation(GO:1990253)
4.4	113.2	GO:0071392	cellular response to estradiol stimulus(GO:0071392)
4.3	12.9	GO:0010768	negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) development involved in symbiotic interaction(GO:0044111) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
4.3	17.2	GO:0046166	glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
4.3	55.5	GO:0050862	positive regulation of T cell receptor signaling pathway(GO:0050862)
4.3	17.1	GO:0009137	purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
4.3	59.7	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
4.2	12.7	GO:0055014	atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
4.2	17.0	GO:0051490	negative regulation of filopodium assembly(GO:0051490)
4.2	21.1	GO:0044351	macropinocytosis(GO:0044351)
4.2	214.3	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
4.2	16.7	GO:0007386	compartment pattern specification(GO:0007386)
4.2	8.4	GO:0071163	DNA replication preinitiation complex assembly(GO:0071163)
4.1	29.0	GO:0035879	plasma membrane lactate transport(GO:0035879)
4.1	37.1	GO:0071578	zinc II ion transmembrane import(GO:0071578)
4.1	65.4	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
4.1	16.3	GO:0002357	defense response to tumor cell(GO:0002357)
4.1	16.3	GO:0035407	histone H3-T11 phosphorylation(GO:0035407)
4.1	36.6	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
4.1	12.2	GO:0009786	regulation of asymmetric cell division(GO:0009786)
4.1	28.4	GO:0002254	kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
4.0	52.5	GO:1904355	positive regulation of telomere capping(GO:1904355)
4.0	383.1	GO:0070527	platelet aggregation(GO:0070527)
4.0	32.3	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
4.0	44.2	GO:0001911	negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
4.0	12.0	GO:0060613	fat pad development(GO:0060613)
4.0	23.8	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
4.0	43.6	GO:0038203	TORC2 signaling(GO:0038203)
4.0	35.6	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
3.9	39.4	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
3.9	105.7	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
3.9	15.6	GO:0000821	regulation of arginine metabolic process(GO:0000821)
3.9	81.9	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
3.9	31.2	GO:0006750	glutathione biosynthetic process(GO:0006750)
3.9	19.5	GO:0007076	mitotic chromosome condensation(GO:0007076)
3.8	77.0	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
3.8	22.8	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
3.8	18.9	GO:0071763	nuclear membrane organization(GO:0071763)
3.8	15.1	GO:1902570	protein localization to nucleolus(GO:1902570)
3.8	37.8	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
3.8	26.3	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
3.7	14.9	GO:0009249	protein lipoylation(GO:0009249)
3.7	14.9	GO:0036229	glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
3.7	22.3	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
3.7	11.1	GO:0039530	MDA-5 signaling pathway(GO:0039530)
3.7	22.3	GO:1900246	positive regulation of RIG-I signaling pathway(GO:1900246)
3.7	11.1	GO:0018160	peptidyl-pyrromethane cofactor linkage(GO:0018160)
3.6	18.2	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
3.6	7.2	GO:1902741	interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
3.6	107.5	GO:0070207	protein homotrimerization(GO:0070207)
3.6	14.3	GO:0016139	glycoside catabolic process(GO:0016139)
3.6	28.6	GO:1903027	regulation of opsonization(GO:1903027)
3.6	35.6	GO:0034498	early endosome to Golgi transport(GO:0034498)
3.5	53.1	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
3.5	21.2	GO:0097052	L-kynurenine metabolic process(GO:0097052)
3.5	204.6	GO:0043488	regulation of mRNA stability(GO:0043488)
3.5	17.5	GO:0016998	cell wall macromolecule catabolic process(GO:0016998)
3.5	38.5	GO:0002315	marginal zone B cell differentiation(GO:0002315)
3.5	10.5	GO:1901895	negative regulation of calcium-transporting ATPase activity(GO:1901895)
3.5	3.5	GO:1904587	response to glycoprotein(GO:1904587)
3.5	3.5	GO:1902566	regulation of eosinophil activation(GO:1902566)
3.5	17.3	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
3.5	17.3	GO:0051014	actin filament severing(GO:0051014)
3.5	6.9	GO:1901339	regulation of store-operated calcium channel activity(GO:1901339)
3.4	13.8	GO:0003366	cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
3.4	44.4	GO:0007172	signal complex assembly(GO:0007172)
3.4	3.4	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
3.4	142.3	GO:0051642	centrosome localization(GO:0051642)
3.4	61.0	GO:0007213	G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
3.4	3.4	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
3.4	33.6	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
3.4	30.2	GO:0006474	N-terminal protein amino acid acetylation(GO:0006474)
3.4	161.3	GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
3.4	26.8	GO:0070543	response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
3.4	20.1	GO:0015680	intracellular copper ion transport(GO:0015680)
3.3	23.4	GO:1903541	regulation of exosomal secretion(GO:1903541)
3.3	13.3	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
3.3	16.6	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
3.3	9.9	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
3.3	66.1	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
3.3	3.3	GO:1901856	negative regulation of cellular respiration(GO:1901856)
3.3	19.7	GO:1902969	mitotic DNA replication(GO:1902969)
3.3	29.5	GO:1904321	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
3.3	9.8	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
3.3	3.3	GO:0071044	histone mRNA catabolic process(GO:0071044)
3.3	29.4	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
3.3	13.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
3.3	153.4	GO:0006891	intra-Golgi vesicle-mediated transport(GO:0006891)
3.3	32.5	GO:0022904	respiratory electron transport chain(GO:0022904)
3.2	55.2	GO:2000758	positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758)
3.2	9.7	GO:0050857	positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
3.2	99.8	GO:0000188	inactivation of MAPK activity(GO:0000188)
3.2	12.8	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
3.2	3.2	GO:2000847	negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
3.2	41.6	GO:0035518	histone H2A monoubiquitination(GO:0035518)
3.2	3.2	GO:0001302	replicative cell aging(GO:0001302)
3.2	16.0	GO:2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
3.2	16.0	GO:0015742	alpha-ketoglutarate transport(GO:0015742)
3.2	28.7	GO:0000722	telomere maintenance via recombination(GO:0000722)
3.2	3.2	GO:0097264	self proteolysis(GO:0097264)
3.2	9.5	GO:0032759	TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
3.2	3.2	GO:2000576	positive regulation of microtubule motor activity(GO:2000576)
3.2	25.3	GO:0035562	negative regulation of chromatin binding(GO:0035562)
3.2	28.4	GO:0060056	mammary gland involution(GO:0060056)
3.1	6.3	GO:0060352	cell adhesion molecule production(GO:0060352)
3.1	6.3	GO:1904117	response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
3.1	18.8	GO:0002230	positive regulation of defense response to virus by host(GO:0002230)
3.1	28.0	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
3.1	21.7	GO:0045793	positive regulation of cell size(GO:0045793)
3.1	18.4	GO:0002943	tRNA dihydrouridine synthesis(GO:0002943)
3.1	24.5	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
3.1	3.1	GO:1903911	positive regulation of postsynaptic membrane organization(GO:1901628) positive regulation of receptor clustering(GO:1903911)
3.1	33.6	GO:0032486	Rap protein signal transduction(GO:0032486)
3.0	3.0	GO:0003228	atrial cardiac muscle tissue development(GO:0003228) atrial cardiac muscle tissue morphogenesis(GO:0055009)
3.0	3.0	GO:0032930	positive regulation of superoxide anion generation(GO:0032930)
3.0	9.1	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
3.0	15.1	GO:0035247	peptidyl-arginine omega-N-methylation(GO:0035247)
3.0	3.0	GO:0002442	serotonin production involved in inflammatory response(GO:0002351) serotonin secretion involved in inflammatory response(GO:0002442) serotonin secretion by platelet(GO:0002554)
3.0	9.0	GO:0090235	regulation of metaphase plate congression(GO:0090235)
3.0	17.9	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
3.0	8.9	GO:1900224	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
3.0	17.8	GO:0009597	detection of virus(GO:0009597)
3.0	3.0	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
3.0	8.9	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
3.0	8.9	GO:1903301	positive regulation of hexokinase activity(GO:1903301)
2.9	2.9	GO:0061034	olfactory bulb mitral cell layer development(GO:0061034)
2.9	63.4	GO:0030042	actin filament depolymerization(GO:0030042)
2.9	2.9	GO:0051884	regulation of anagen(GO:0051884)
2.8	70.5	GO:0032008	positive regulation of TOR signaling(GO:0032008)
2.8	5.6	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
2.8	11.2	GO:0039663	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
2.8	22.4	GO:0002934	desmosome organization(GO:0002934)
2.8	42.0	GO:0035855	megakaryocyte development(GO:0035855)
2.8	39.1	GO:0060632	regulation of microtubule-based movement(GO:0060632)
2.8	8.4	GO:0050653	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
2.8	105.6	GO:0051865	protein autoubiquitination(GO:0051865)
2.8	27.7	GO:0051290	protein heterotetramerization(GO:0051290)
2.8	159.6	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
2.8	5.5	GO:0090234	regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
2.7	178.4	GO:0002220	innate immune response activating cell surface receptor signaling pathway(GO:0002220)
2.7	10.9	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
2.7	24.5	GO:0006089	lactate metabolic process(GO:0006089)
2.7	24.5	GO:0000733	DNA strand renaturation(GO:0000733)
2.7	19.0	GO:0030421	defecation(GO:0030421)
2.7	16.3	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
2.7	43.4	GO:0033006	regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
2.7	8.1	GO:0006264	mitochondrial DNA replication(GO:0006264)
2.7	18.9	GO:0043306	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
2.7	48.6	GO:0006491	N-glycan processing(GO:0006491)
2.7	16.2	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
2.7	24.2	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
2.7	18.8	GO:0007619	courtship behavior(GO:0007619)
2.7	18.8	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
2.6	123.7	GO:0043171	peptide catabolic process(GO:0043171)
2.6	13.0	GO:0043418	homocysteine catabolic process(GO:0043418)
2.6	10.4	GO:0061643	chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
2.6	7.8	GO:0046521	sphingoid catabolic process(GO:0046521)
2.6	7.8	GO:1903976	negative regulation of glial cell migration(GO:1903976)
2.6	76.7	GO:0006611	protein export from nucleus(GO:0006611)
2.5	5.1	GO:0043323	regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
2.5	10.1	GO:0042631	cellular response to water deprivation(GO:0042631) cellular response to water stimulus(GO:0071462)
2.5	38.0	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
2.5	55.1	GO:2000249	regulation of actin cytoskeleton reorganization(GO:2000249)
2.5	25.0	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
2.5	37.4	GO:0000002	mitochondrial genome maintenance(GO:0000002)
2.5	5.0	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
2.5	17.3	GO:0071421	manganese ion transmembrane transport(GO:0071421)
2.5	4.9	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
2.4	68.6	GO:0061641	chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
2.4	31.7	GO:0007220	Notch receptor processing(GO:0007220)
2.4	7.3	GO:0060267	positive regulation of respiratory burst(GO:0060267)
2.4	120.6	GO:0032781	positive regulation of ATPase activity(GO:0032781)
2.4	7.2	GO:0048194	Golgi vesicle budding(GO:0048194)
2.4	9.6	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
2.4	35.9	GO:2000144	positive regulation of DNA-templated transcription, initiation(GO:2000144)
2.4	2.4	GO:0001927	exocyst assembly(GO:0001927)
2.4	7.1	GO:0042357	thiamine diphosphate metabolic process(GO:0042357)
2.4	2.4	GO:0048378	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
2.3	4.7	GO:0002415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
2.3	11.7	GO:0034127	regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034127) negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
2.3	30.4	GO:0043153	entrainment of circadian clock by photoperiod(GO:0043153)
2.3	11.7	GO:1903299	regulation of hexokinase activity(GO:1903299)
2.3	7.0	GO:0036079	GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
2.3	2.3	GO:0007343	egg activation(GO:0007343)
2.3	32.5	GO:0021670	lateral ventricle development(GO:0021670)
2.3	7.0	GO:0071963	establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
2.3	6.9	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
2.3	13.7	GO:1904274	tricellular tight junction assembly(GO:1904274)
2.3	15.9	GO:0003433	chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
2.3	13.6	GO:0060050	positive regulation of protein glycosylation(GO:0060050)
2.3	4.5	GO:0006196	AMP catabolic process(GO:0006196)
2.3	11.3	GO:0048050	post-embryonic eye morphogenesis(GO:0048050)
2.2	9.0	GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
2.2	20.2	GO:0048227	plasma membrane to endosome transport(GO:0048227)
2.2	6.7	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
2.2	35.6	GO:0018345	protein palmitoylation(GO:0018345)
2.2	8.9	GO:0043382	regulation of memory T cell differentiation(GO:0043380) positive regulation of memory T cell differentiation(GO:0043382)
2.2	41.6	GO:0034383	low-density lipoprotein particle clearance(GO:0034383)
2.2	6.6	GO:0002384	hepatic immune response(GO:0002384)
2.2	10.9	GO:0015793	glycerol transport(GO:0015793)
2.2	58.4	GO:0007029	endoplasmic reticulum organization(GO:0007029)
2.2	4.3	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
2.2	28.0	GO:0009313	oligosaccharide catabolic process(GO:0009313)
2.2	8.6	GO:0010592	positive regulation of lamellipodium assembly(GO:0010592)
2.1	15.0	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
2.1	8.5	GO:0021691	cerebellar Purkinje cell layer maturation(GO:0021691)
2.1	6.4	GO:2000563	positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
2.1	6.4	GO:0006642	triglyceride mobilization(GO:0006642)
2.1	6.4	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
2.1	4.2	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
2.1	67.5	GO:0006414	translational elongation(GO:0006414)
2.1	4.2	GO:0009191	ribonucleoside diphosphate catabolic process(GO:0009191)
2.1	6.3	GO:0045065	cytotoxic T cell differentiation(GO:0045065)
2.1	12.6	GO:0033235	positive regulation of protein sumoylation(GO:0033235)
2.1	27.2	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
2.1	22.9	GO:0036342	post-anal tail morphogenesis(GO:0036342)
2.1	20.7	GO:0007021	tubulin complex assembly(GO:0007021)
2.1	2.1	GO:0010992	ubiquitin homeostasis(GO:0010992)
2.1	8.2	GO:0070525	tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
2.0	10.2	GO:0045579	positive regulation of B cell differentiation(GO:0045579)
2.0	8.1	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
2.0	6.0	GO:0045356	positive regulation of interferon-alpha biosynthetic process(GO:0045356)
2.0	306.8	GO:0008360	regulation of cell shape(GO:0008360)
2.0	12.0	GO:0042761	fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
2.0	9.9	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
2.0	9.9	GO:0071732	cellular response to nitric oxide(GO:0071732)
2.0	17.8	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)
2.0	3.9	GO:0061009	common bile duct development(GO:0061009)
1.9	13.5	GO:0035897	proteolysis in other organism(GO:0035897)
1.9	42.4	GO:0006487	protein N-linked glycosylation(GO:0006487)
1.9	21.0	GO:0006552	leucine catabolic process(GO:0006552)
1.9	3.8	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
1.9	7.6	GO:0000212	meiotic spindle organization(GO:0000212)
1.9	20.9	GO:0070206	protein trimerization(GO:0070206)
1.9	5.7	GO:0060957	endocardial cell fate commitment(GO:0060957) endocardial cushion cell differentiation(GO:0061443) endocardial cushion cell fate commitment(GO:0061445) positive regulation of determination of dorsal identity(GO:2000017)
1.9	9.4	GO:2001205	negative regulation of osteoclast development(GO:2001205)
1.9	3.8	GO:0035747	natural killer cell chemotaxis(GO:0035747)
1.9	11.3	GO:0006564	L-serine biosynthetic process(GO:0006564)
1.9	13.1	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
1.9	7.5	GO:0090009	primitive streak formation(GO:0090009)
1.9	9.3	GO:0002347	response to tumor cell(GO:0002347)
1.8	16.5	GO:0097320	membrane tubulation(GO:0097320)
1.8	1.8	GO:0070202	regulation of establishment of protein localization to chromosome(GO:0070202)
1.8	12.7	GO:0036010	protein localization to endosome(GO:0036010)
1.8	3.6	GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516)
1.8	12.5	GO:0035456	response to interferon-beta(GO:0035456)
1.8	3.6	GO:0021569	rhombomere 3 development(GO:0021569)
1.8	44.2	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
1.7	12.2	GO:0006116	NADH oxidation(GO:0006116)
1.7	10.4	GO:0038092	nodal signaling pathway(GO:0038092)
1.7	1.7	GO:0033004	negative regulation of mast cell activation(GO:0033004)
1.7	12.0	GO:0042074	cell migration involved in gastrulation(GO:0042074)
1.7	1.7	GO:0060066	oviduct development(GO:0060066)
1.7	5.1	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
1.7	3.4	GO:0006059	hexitol metabolic process(GO:0006059)
1.7	61.2	GO:0006110	regulation of glycolytic process(GO:0006110)
1.7	3.4	GO:0061394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
1.7	5.1	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
1.7	8.3	GO:0046490	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate metabolic process(GO:0046490)
1.6	11.5	GO:2000172	regulation of branching morphogenesis of a nerve(GO:2000172)
1.6	1.6	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
1.6	9.9	GO:0043555	regulation of translation in response to stress(GO:0043555)
1.6	13.1	GO:0045059	positive thymic T cell selection(GO:0045059)
1.6	13.0	GO:0042789	mRNA transcription from RNA polymerase II promoter(GO:0042789)
1.6	3.2	GO:1902463	establishment of Sertoli cell barrier(GO:0097368) protein localization to cell leading edge(GO:1902463)
1.6	11.2	GO:0030091	protein repair(GO:0030091)
1.6	3.2	GO:0070384	Harderian gland development(GO:0070384)
1.6	30.2	GO:0006513	protein monoubiquitination(GO:0006513)
1.6	99.5	GO:0034728	nucleosome organization(GO:0034728)
1.6	11.0	GO:0021903	rostrocaudal neural tube patterning(GO:0021903)
1.6	44.0	GO:0031581	hemidesmosome assembly(GO:0031581)
1.6	4.7	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
1.6	17.1	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
1.5	4.6	GO:0002304	gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
1.5	9.1	GO:0031639	plasminogen activation(GO:0031639)
1.5	9.1	GO:1902031	regulation of NADP metabolic process(GO:1902031)
1.5	1.5	GO:2000566	CD8-positive, alpha-beta T cell proliferation(GO:0035740) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
1.5	4.5	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
1.5	7.4	GO:0001880	Mullerian duct regression(GO:0001880)
1.5	17.8	GO:0032516	positive regulation of phosphoprotein phosphatase activity(GO:0032516)
1.5	4.4	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
1.5	1.5	GO:0001916	positive regulation of T cell mediated cytotoxicity(GO:0001916)
1.5	5.8	GO:0046947	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
1.4	4.3	GO:0035720	intraciliary anterograde transport(GO:0035720)
1.4	7.1	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
1.4	39.6	GO:0061640	cytoskeleton-dependent cytokinesis(GO:0061640)
1.4	4.2	GO:1903224	regulation of endodermal cell differentiation(GO:1903224)
1.4	12.7	GO:0042178	xenobiotic catabolic process(GO:0042178)
1.4	9.6	GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086)
1.4	11.0	GO:0010664	negative regulation of striated muscle cell apoptotic process(GO:0010664)
1.4	2.7	GO:0051944	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
1.3	20.2	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
1.3	170.8	GO:0006457	protein folding(GO:0006457)
1.3	3.9	GO:2000317	negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
1.3	14.3	GO:0007096	regulation of exit from mitosis(GO:0007096)
1.3	2.6	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
1.3	15.2	GO:2001223	negative regulation of neuron migration(GO:2001223)
1.3	7.6	GO:0034205	beta-amyloid formation(GO:0034205)
1.3	3.8	GO:0032020	ISG15-protein conjugation(GO:0032020)
1.3	41.4	GO:0050766	positive regulation of phagocytosis(GO:0050766)
1.2	5.0	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
1.2	3.7	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
1.2	3.7	GO:0001574	ganglioside biosynthetic process(GO:0001574)
1.2	7.4	GO:0098989	NMDA selective glutamate receptor signaling pathway(GO:0098989)
1.2	7.3	GO:0000012	single strand break repair(GO:0000012)
1.2	7.3	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
1.2	6.1	GO:0033227	dsRNA transport(GO:0033227)
1.2	4.8	GO:0010591	regulation of lamellipodium assembly(GO:0010591)
1.2	20.5	GO:0033689	negative regulation of osteoblast proliferation(GO:0033689)
1.2	1.2	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
1.2	82.5	GO:0006626	protein targeting to mitochondrion(GO:0006626)
1.2	1.2	GO:0050904	diapedesis(GO:0050904)
1.2	4.8	GO:0090084	negative regulation of inclusion body assembly(GO:0090084)
1.2	4.7	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
1.2	5.9	GO:0098543	detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
1.2	9.5	GO:0045064	T-helper 2 cell differentiation(GO:0045064)
1.2	8.3	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
1.2	8.3	GO:0060576	intestinal epithelial cell development(GO:0060576)
1.2	5.9	GO:0006551	leucine metabolic process(GO:0006551) branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
1.2	25.8	GO:0006270	DNA replication initiation(GO:0006270)
1.2	16.3	GO:0090224	regulation of spindle organization(GO:0090224)
1.2	11.6	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
1.2	4.6	GO:0040016	embryonic cleavage(GO:0040016)
1.2	57.8	GO:0051289	protein homotetramerization(GO:0051289)
1.1	59.4	GO:0006364	rRNA processing(GO:0006364)
1.1	20.5	GO:0044804	nucleophagy(GO:0044804)
1.1	3.4	GO:0035995	detection of muscle stretch(GO:0035995)
1.1	1.1	GO:1905069	negative regulation of mononuclear cell migration(GO:0071676) allantois development(GO:1905069)
1.1	5.6	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
1.1	5.6	GO:0046449	creatinine metabolic process(GO:0046449)
1.1	23.3	GO:0007176	regulation of epidermal growth factor-activated receptor activity(GO:0007176)
1.1	6.6	GO:0015886	heme transport(GO:0015886)
1.1	34.1	GO:0008210	estrogen metabolic process(GO:0008210)
1.1	14.1	GO:0035455	response to interferon-alpha(GO:0035455)
1.1	2.2	GO:0002711	positive regulation of T cell mediated immunity(GO:0002711)
1.1	373.0	GO:0002283	neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
1.1	4.3	GO:0090481	pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
1.1	30.7	GO:0032481	positive regulation of type I interferon production(GO:0032481)
1.1	2.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
1.1	3.2	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
1.1	53.6	GO:0006910	phagocytosis, recognition(GO:0006910)
1.1	82.0	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043123)
1.0	18.2	GO:0006418	tRNA aminoacylation for protein translation(GO:0006418)
1.0	5.1	GO:0006573	valine metabolic process(GO:0006573)
1.0	5.0	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
1.0	24.1	GO:0015721	bile acid and bile salt transport(GO:0015721)
1.0	4.0	GO:0035965	cardiolipin acyl-chain remodeling(GO:0035965)
1.0	27.7	GO:0015893	drug transport(GO:0015893)
1.0	7.9	GO:0035065	regulation of histone acetylation(GO:0035065)
1.0	3.8	GO:0051352	negative regulation of ligase activity(GO:0051352)
1.0	13.4	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
1.0	1.9	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
1.0	17.1	GO:0008053	mitochondrial fusion(GO:0008053)
0.9	1.9	GO:0006521	regulation of cellular amino acid metabolic process(GO:0006521)
0.9	8.4	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.9	1.8	GO:0031268	pseudopodium organization(GO:0031268)
0.9	8.1	GO:0051383	kinetochore organization(GO:0051383)
0.9	2.7	GO:0051683	establishment of Golgi localization(GO:0051683)
0.9	1.8	GO:0050902	leukocyte adhesive activation(GO:0050902)
0.9	3.5	GO:0061635	regulation of protein complex stability(GO:0061635)
0.9	0.9	GO:0006771	riboflavin metabolic process(GO:0006771) flavin-containing compound metabolic process(GO:0042726)
0.9	5.1	GO:0032793	positive regulation of CREB transcription factor activity(GO:0032793)
0.9	4.3	GO:0002335	mature B cell differentiation(GO:0002335)
0.9	11.9	GO:0035987	endodermal cell differentiation(GO:0035987)
0.8	10.1	GO:0097502	mannosylation(GO:0097502)
0.8	2.5	GO:2001045	closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.8	2.5	GO:0090675	intermicrovillar adhesion(GO:0090675)
0.8	70.4	GO:0002576	platelet degranulation(GO:0002576)
0.8	4.9	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.8	1.6	GO:0010677	negative regulation of cellular carbohydrate metabolic process(GO:0010677)
0.8	5.5	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.8	5.5	GO:0043162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.8	3.9	GO:0044557	relaxation of smooth muscle(GO:0044557)
0.8	6.3	GO:0060644	mammary gland epithelial cell differentiation(GO:0060644)
0.8	3.9	GO:1902659	regulation of glucose mediated signaling pathway(GO:1902659)
0.8	12.5	GO:0048246	macrophage chemotaxis(GO:0048246)
0.8	2.3	GO:0032025	response to cobalt ion(GO:0032025)
0.8	24.8	GO:0006582	melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.8	1.5	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.8	9.2	GO:0045668	negative regulation of osteoblast differentiation(GO:0045668)
0.8	0.8	GO:1990481	mRNA pseudouridine synthesis(GO:1990481)
0.7	1.5	GO:0060536	cartilage morphogenesis(GO:0060536)
0.7	4.5	GO:0043374	CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.7	8.0	GO:1990090	cellular response to nerve growth factor stimulus(GO:1990090)
0.7	9.4	GO:0003298	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.7	2.2	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.7	2.9	GO:0018197	peptidyl-aspartic acid modification(GO:0018197) peptidyl-aspartic acid hydroxylation(GO:0042264)
0.7	6.2	GO:1900047	negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.7	6.9	GO:0048007	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.7	4.8	GO:0090382	phagosome maturation(GO:0090382)
0.7	6.1	GO:0048311	mitochondrion distribution(GO:0048311)
0.7	0.7	GO:0045649	regulation of macrophage differentiation(GO:0045649)
0.7	0.7	GO:0019184	nonribosomal peptide biosynthetic process(GO:0019184)
0.7	5.4	GO:0051764	actin crosslink formation(GO:0051764)
0.7	34.0	GO:0019886	antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.7	2.0	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.7	1.3	GO:0051561	negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471) positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.7	11.2	GO:0007019	microtubule depolymerization(GO:0007019)
0.6	1.9	GO:0031053	primary miRNA processing(GO:0031053)
0.6	10.8	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.6	8.2	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.6	2.5	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.6	1.9	GO:0061031	subthalamic nucleus development(GO:0021763) prolactin secreting cell differentiation(GO:0060127) left lung development(GO:0060459) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578) endodermal digestive tract morphogenesis(GO:0061031)
0.6	10.8	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.6	2.9	GO:0045617	negative regulation of keratinocyte differentiation(GO:0045617)
0.6	1.1	GO:1904693	midbrain morphogenesis(GO:1904693)
0.6	2.8	GO:0031944	negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of steroid hormone biosynthetic process(GO:0090032)
0.5	2.1	GO:0051599	response to hydrostatic pressure(GO:0051599)
0.5	20.0	GO:0030521	androgen receptor signaling pathway(GO:0030521)
0.5	1.6	GO:0046532	regulation of photoreceptor cell differentiation(GO:0046532)
0.5	2.6	GO:0030263	apoptotic chromosome condensation(GO:0030263)
0.5	9.8	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.5	3.1	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.5	6.1	GO:0031163	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.5	3.5	GO:0042167	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.5	1.5	GO:0097201	negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.5	3.9	GO:0034656	nucleobase-containing small molecule catabolic process(GO:0034656)
0.5	3.0	GO:0060372	regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.5	45.0	GO:0071774	response to fibroblast growth factor(GO:0071774)
0.5	1.9	GO:0007185	transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.5	0.5	GO:0052564	response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.5	31.4	GO:0045445	myoblast differentiation(GO:0045445)
0.5	1.4	GO:0051150	regulation of smooth muscle cell differentiation(GO:0051150)
0.5	9.8	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress(GO:0070059)
0.5	4.1	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.4	4.5	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.4	2.7	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.4	3.1	GO:0007143	female meiotic division(GO:0007143)
0.4	4.8	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.4	5.0	GO:0048268	clathrin coat assembly(GO:0048268)
0.4	1.6	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
0.4	3.6	GO:0050435	beta-amyloid metabolic process(GO:0050435)
0.4	2.8	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
0.4	1.6	GO:0045577	regulation of B cell differentiation(GO:0045577)
0.4	1.1	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.4	1.5	GO:0035750	protein localization to myelin sheath abaxonal region(GO:0035750)
0.4	5.4	GO:0051149	positive regulation of muscle cell differentiation(GO:0051149)
0.4	2.5	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.3	0.7	GO:0070272	proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.3	0.7	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.3	23.2	GO:0002433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis(GO:0002433) Fc-gamma receptor signaling pathway involved in phagocytosis(GO:0038096)
0.3	2.1	GO:0009642	response to light intensity(GO:0009642)
0.3	0.9	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.3	1.2	GO:0061117	negative regulation of cardiac muscle tissue growth(GO:0055022) negative regulation of heart growth(GO:0061117)
0.3	1.2	GO:0015677	copper ion import(GO:0015677)
0.3	1.6	GO:1903566	positive regulation of protein localization to cilium(GO:1903566)
0.3	0.3	GO:0009794	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.3	1.0	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.3	0.5	GO:0042418	epinephrine biosynthetic process(GO:0042418)
0.2	1.0	GO:0032753	positive regulation of interleukin-4 production(GO:0032753)
0.2	1.7	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.2	1.2	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.2	0.9	GO:1903385	regulation of homophilic cell adhesion(GO:1903385)
0.2	2.5	GO:0042531	positive regulation of tyrosine phosphorylation of STAT protein(GO:0042531)
0.2	2.0	GO:0002053	positive regulation of mesenchymal cell proliferation(GO:0002053)
0.2	3.6	GO:2000179	positive regulation of neural precursor cell proliferation(GO:2000179)
0.2	4.6	GO:0009235	cobalamin metabolic process(GO:0009235)
0.2	0.2	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.2	0.6	GO:1902081	regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.2	1.2	GO:0019884	antigen processing and presentation of exogenous antigen(GO:0019884)
0.2	0.8	GO:0031507	heterochromatin assembly(GO:0031507)
0.2	4.1	GO:0061003	positive regulation of dendritic spine morphogenesis(GO:0061003)
0.2	0.6	GO:0000103	sulfate assimilation(GO:0000103)
0.2	0.7	GO:0033306	phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.2	0.7	GO:0090259	regulation of retinal ganglion cell axon guidance(GO:0090259)
0.2	0.7	GO:0034334	adherens junction maintenance(GO:0034334)
0.2	0.9	GO:0050684	regulation of mRNA processing(GO:0050684)
0.2	6.2	GO:0006338	chromatin remodeling(GO:0006338)
0.2	0.3	GO:0043922	negative regulation by host of viral transcription(GO:0043922)
0.1	0.6	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.1	0.6	GO:0031468	nuclear envelope reassembly(GO:0031468)
0.1	1.6	GO:0032060	bleb assembly(GO:0032060)
0.1	0.7	GO:0045069	regulation of viral genome replication(GO:0045069)
0.1	0.6	GO:0002074	extraocular skeletal muscle development(GO:0002074)
0.1	0.9	GO:1901186	positive regulation of ERBB signaling pathway(GO:1901186)
0.1	0.7	GO:0008218	bioluminescence(GO:0008218)
0.1	0.2	GO:1990418	response to insulin-like growth factor stimulus(GO:1990418)
0.1	0.7	GO:0072697	protein localization to cell cortex(GO:0072697)
0.1	0.1	GO:0048313	Golgi inheritance(GO:0048313)
0.1	0.7	GO:1905123	regulation of glucosylceramidase activity(GO:1905123)
0.1	1.3	GO:0035902	response to immobilization stress(GO:0035902)
0.1	0.2	GO:0035425	autocrine signaling(GO:0035425)
0.1	6.8	GO:0050851	antigen receptor-mediated signaling pathway(GO:0050851)
0.1	0.3	GO:0060512	prostate gland morphogenesis(GO:0060512)
0.1	0.5	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.1	0.3	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.1	0.2	GO:0060837	blood vessel endothelial cell differentiation(GO:0060837) arterial endothelial cell differentiation(GO:0060842)
0.1	0.2	GO:0048014	Tie signaling pathway(GO:0048014) negative regulation of positive chemotaxis(GO:0050928)
0.1	0.5	GO:0002115	store-operated calcium entry(GO:0002115)
0.0	0.5	GO:0090162	establishment of epithelial cell polarity(GO:0090162)
0.0	0.1	GO:0070314	G1 to G0 transition(GO:0070314)
0.0	0.5	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.1	GO:0014886	transition between slow and fast fiber(GO:0014886)
0.0	0.1	GO:0010716	negative regulation of extracellular matrix disassembly(GO:0010716)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
100.7	1006.9	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
79.4	238.2	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
73.8	369.2	GO:0000408	EKC/KEOPS complex(GO:0000408)
69.2	484.4	GO:0034715	pICln-Sm protein complex(GO:0034715)
66.0	264.2	GO:0005683	U7 snRNP(GO:0005683)
63.8	766.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
46.2	46.2	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
45.2	316.1	GO:1990111	spermatoproteasome complex(GO:1990111)
44.1	220.6	GO:1902560	GMP reductase complex(GO:1902560)
44.1	88.2	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
44.1	396.5	GO:0005787	signal peptidase complex(GO:0005787)
43.8	131.3	GO:0071001	U4/U6 snRNP(GO:0071001)
43.0	172.1	GO:0071986	Ragulator complex(GO:0071986)
40.4	121.3	GO:0018444	translation release factor complex(GO:0018444)
39.2	391.8	GO:0031595	nuclear proteasome complex(GO:0031595)
38.8	194.1	GO:0042643	actomyosin, actin portion(GO:0042643)
35.2	105.6	GO:0071817	MMXD complex(GO:0071817)
34.9	349.1	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
34.3	205.8	GO:0000172	ribonuclease MRP complex(GO:0000172)
32.0	192.3	GO:0034709	methylosome(GO:0034709)
31.8	254.4	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
31.7	126.8	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
31.6	221.3	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
31.2	218.3	GO:0032021	NELF complex(GO:0032021)
31.0	620.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
31.0	185.7	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
30.9	30.9	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
30.7	92.1	GO:0030289	protein phosphatase 4 complex(GO:0030289)
29.8	59.7	GO:0070435	Shc-EGFR complex(GO:0070435)
29.5	236.3	GO:0005688	U6 snRNP(GO:0005688)
29.1	406.7	GO:0005686	U2 snRNP(GO:0005686)
28.7	86.2	GO:0005674	transcription factor TFIIF complex(GO:0005674)
28.5	313.9	GO:0005838	proteasome regulatory particle(GO:0005838)
27.5	247.6	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
27.5	247.3	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
27.2	896.5	GO:0030687	preribosome, large subunit precursor(GO:0030687)
26.9	295.5	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
26.5	79.5	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
26.2	183.5	GO:0090661	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
25.6	230.4	GO:0072546	ER membrane protein complex(GO:0072546)
25.2	454.1	GO:0030127	COPII vesicle coat(GO:0030127)
25.0	150.2	GO:0071797	LUBAC complex(GO:0071797)
24.9	199.1	GO:0019774	proteasome core complex, beta-subunit complex(GO:0019774)
24.1	120.7	GO:0033503	HULC complex(GO:0033503)
23.3	139.7	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
23.2	116.2	GO:0045272	plasma membrane respiratory chain complex I(GO:0045272)
23.1	69.2	GO:0097441	basilar dendrite(GO:0097441)
22.9	68.8	GO:0048269	methionine adenosyltransferase complex(GO:0048269)
22.7	113.4	GO:0097149	centralspindlin complex(GO:0097149)
22.5	67.5	GO:0009328	phenylalanine-tRNA ligase complex(GO:0009328)
21.6	86.5	GO:0071920	cleavage body(GO:0071920)
21.4	256.6	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
21.1	63.2	GO:0017102	methionyl glutamyl tRNA synthetase complex(GO:0017102)
21.0	168.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
20.8	104.1	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
20.7	310.2	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
20.6	267.5	GO:0002199	zona pellucida receptor complex(GO:0002199)
20.5	225.4	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
20.4	387.0	GO:0030686	90S preribosome(GO:0030686)
20.1	362.5	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
20.1	160.9	GO:0070522	nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
20.0	199.9	GO:0097255	R2TP complex(GO:0097255)
19.9	536.4	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
19.5	58.6	GO:0034677	integrin alpha7-beta1 complex(GO:0034677)
19.4	77.8	GO:0071159	NF-kappaB complex(GO:0071159)
19.0	114.1	GO:0061617	MICOS complex(GO:0061617)
18.6	167.6	GO:0032133	chromosome passenger complex(GO:0032133)
18.6	55.7	GO:0034271	phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
18.4	92.2	GO:0034688	integrin alphaM-beta2 complex(GO:0034688)
18.2	182.1	GO:0097526	spliceosomal tri-snRNP complex(GO:0097526)
18.2	72.7	GO:0031510	SUMO activating enzyme complex(GO:0031510)
17.9	17.9	GO:0005687	U4 snRNP(GO:0005687)
17.8	1854.2	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
17.2	120.6	GO:0098560	cytoplasmic side of late endosome membrane(GO:0098560)
17.2	68.7	GO:0036502	Derlin-1-VIMP complex(GO:0036502)
17.1	274.2	GO:0031080	nuclear pore outer ring(GO:0031080)
17.1	205.4	GO:0071203	WASH complex(GO:0071203)
17.0	51.0	GO:0030532	small nuclear ribonucleoprotein complex(GO:0030532)
16.5	462.3	GO:0005763	organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
15.8	31.6	GO:0035061	interchromatin granule(GO:0035061)
15.7	62.8	GO:0098592	cytoplasmic side of apical plasma membrane(GO:0098592)
15.6	124.9	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
15.5	108.4	GO:0016272	prefoldin complex(GO:0016272)
15.4	215.7	GO:0090543	Flemming body(GO:0090543)
15.2	106.2	GO:0005956	protein kinase CK2 complex(GO:0005956)
15.1	121.1	GO:0000796	condensin complex(GO:0000796)
15.1	256.5	GO:0005662	DNA replication factor A complex(GO:0005662)
15.1	45.2	GO:0036387	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
14.8	607.3	GO:0015934	large ribosomal subunit(GO:0015934)
14.6	29.3	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
14.6	58.2	GO:0030915	Smc5-Smc6 complex(GO:0030915)
14.5	303.9	GO:0097342	ripoptosome(GO:0097342)
14.3	43.0	GO:0097550	transcriptional preinitiation complex(GO:0097550)
14.2	71.2	GO:0043564	Ku70:Ku80 complex(GO:0043564)
14.2	412.9	GO:0005680	anaphase-promoting complex(GO:0005680)
14.2	99.6	GO:0044530	supraspliceosomal complex(GO:0044530)
14.0	84.0	GO:0002178	palmitoyltransferase complex(GO:0002178)
13.8	69.0	GO:0036396	MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
13.7	68.4	GO:0070765	gamma-secretase complex(GO:0070765)
13.6	54.4	GO:0030904	retromer complex(GO:0030904)
13.5	53.9	GO:0070876	SOSS complex(GO:0070876)
13.4	53.5	GO:0044613	nuclear pore central transport channel(GO:0044613)
13.4	160.3	GO:0000815	ESCRT III complex(GO:0000815)
13.3	199.6	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
13.2	210.9	GO:0032040	small-subunit processome(GO:0032040)
13.2	171.3	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
13.2	52.6	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
12.8	51.3	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
12.6	63.2	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
12.6	151.3	GO:0042555	MCM complex(GO:0042555)
12.4	148.5	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
12.3	160.0	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
12.3	159.7	GO:0036452	ESCRT complex(GO:0036452)
12.2	146.5	GO:0030008	TRAPP complex(GO:0030008)
12.2	36.5	GO:0045323	interleukin-1 receptor complex(GO:0045323)
12.2	109.4	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
12.0	36.1	GO:0044611	nuclear pore inner ring(GO:0044611)
12.0	168.4	GO:0044615	nuclear pore nuclear basket(GO:0044615)
12.0	48.1	GO:0000811	GINS complex(GO:0000811)
12.0	71.7	GO:0070552	BRISC complex(GO:0070552)
11.9	35.7	GO:0030684	preribosome(GO:0030684)
11.8	59.0	GO:0031436	BRCA1-BARD1 complex(GO:0031436)
11.7	727.6	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
11.5	80.6	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
11.4	250.5	GO:0036020	endolysosome membrane(GO:0036020)
11.3	124.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
11.3	11.3	GO:0098574	cytoplasmic side of lysosomal membrane(GO:0098574)
11.2	112.3	GO:0032039	integrator complex(GO:0032039)
11.0	121.5	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
10.9	10.9	GO:0001652	granular component(GO:0001652)
10.7	53.5	GO:0071598	neuronal ribonucleoprotein granule(GO:0071598)
10.4	94.0	GO:0042382	paraspeckles(GO:0042382)
10.2	122.8	GO:0097136	Bcl-2 family protein complex(GO:0097136)
10.1	50.7	GO:0098837	postsynaptic recycling endosome(GO:0098837)
10.1	140.9	GO:0005685	U1 snRNP(GO:0005685)
10.0	100.4	GO:0044194	cytolytic granule(GO:0044194)
10.0	90.2	GO:0000439	core TFIIH complex(GO:0000439)
10.0	49.9	GO:0005785	signal recognition particle receptor complex(GO:0005785)
10.0	39.9	GO:0031298	replication fork protection complex(GO:0031298)
10.0	29.9	GO:0031262	Ndc80 complex(GO:0031262)
9.9	49.7	GO:0005854	nascent polypeptide-associated complex(GO:0005854)
9.9	39.4	GO:0005846	nuclear cap binding complex(GO:0005846)
9.8	29.3	GO:0035370	UBC13-UEV1A complex(GO:0035370)
9.7	107.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
9.7	19.4	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
9.7	87.4	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
9.5	76.3	GO:0005684	U2-type spliceosomal complex(GO:0005684)
9.2	46.2	GO:0098554	cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
9.2	27.7	GO:0070939	Dsl1p complex(GO:0070939)
9.2	220.1	GO:0035327	transcriptionally active chromatin(GO:0035327)
9.2	27.5	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
9.1	463.0	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
9.1	1115.9	GO:0035578	azurophil granule lumen(GO:0035578)
9.0	126.5	GO:0001673	male germ cell nucleus(GO:0001673)
9.0	135.0	GO:0033202	Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
9.0	44.9	GO:0032044	DSIF complex(GO:0032044)
9.0	71.7	GO:0097452	GAIT complex(GO:0097452)
9.0	26.9	GO:1990913	sperm head plasma membrane(GO:1990913) ooplasm(GO:1990917)
8.7	87.4	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
8.6	51.7	GO:0060171	stereocilium membrane(GO:0060171)
8.4	33.7	GO:1990356	sumoylated E2 ligase complex(GO:1990356)
8.4	58.9	GO:0015935	small ribosomal subunit(GO:0015935)
8.4	25.2	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
8.4	276.3	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
8.4	8.4	GO:0005732	small nucleolar ribonucleoprotein complex(GO:0005732)
8.2	24.5	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
7.9	1272.0	GO:0005681	spliceosomal complex(GO:0005681)
7.9	39.7	GO:0089701	U2AF(GO:0089701)
7.9	87.4	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
7.9	39.7	GO:0009368	endopeptidase Clp complex(GO:0009368)
7.9	118.5	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
7.9	157.5	GO:0042101	T cell receptor complex(GO:0042101)
7.8	86.3	GO:0030870	Mre11 complex(GO:0030870)
7.8	23.5	GO:0000805	X chromosome(GO:0000805)
7.7	77.3	GO:0030125	clathrin vesicle coat(GO:0030125)
7.7	162.3	GO:0070971	endoplasmic reticulum exit site(GO:0070971)
7.6	434.6	GO:0035577	azurophil granule membrane(GO:0035577)
7.6	22.8	GO:0008623	CHRAC(GO:0008623)
7.5	37.7	GO:0031523	Myb complex(GO:0031523)
7.4	29.8	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
7.4	51.8	GO:0033276	transcription factor TFTC complex(GO:0033276)
7.4	95.6	GO:0017119	Golgi transport complex(GO:0017119)
7.3	50.9	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
7.2	14.3	GO:0000939	condensed chromosome inner kinetochore(GO:0000939)
7.1	35.5	GO:0045283	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
7.0	7.0	GO:0055087	Ski complex(GO:0055087)
7.0	396.9	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
6.9	34.7	GO:0043625	delta DNA polymerase complex(GO:0043625)
6.9	48.5	GO:0034518	RNA cap binding complex(GO:0034518)
6.9	48.4	GO:0043203	axon hillock(GO:0043203)
6.9	89.4	GO:0031209	SCAR complex(GO:0031209)
6.9	27.4	GO:1990589	ATF4-CREB1 transcription factor complex(GO:1990589)
6.6	39.6	GO:0030905	retromer, tubulation complex(GO:0030905)
6.6	203.2	GO:0016469	proton-transporting two-sector ATPase complex(GO:0016469)
6.5	32.7	GO:1990425	ryanodine receptor complex(GO:1990425)
6.5	52.2	GO:0042588	zymogen granule(GO:0042588)
6.5	91.2	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
6.5	32.4	GO:0032301	MutSalpha complex(GO:0032301)
6.5	25.8	GO:0020003	symbiont-containing vacuole(GO:0020003)
6.4	147.6	GO:0035098	ESC/E(Z) complex(GO:0035098)
6.4	44.8	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
6.4	12.8	GO:0070557	PCNA-p21 complex(GO:0070557)
6.4	19.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
6.3	279.2	GO:0090544	BAF-type complex(GO:0090544)
6.3	69.0	GO:0033588	Elongator holoenzyme complex(GO:0033588)
6.3	332.4	GO:0001772	immunological synapse(GO:0001772)
6.2	31.0	GO:0030891	VCB complex(GO:0030891)
6.2	265.7	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
6.1	12.2	GO:0071062	alphav-beta3 integrin-vitronectin complex(GO:0071062)
6.1	12.2	GO:0036449	microtubule minus-end(GO:0036449)
6.0	12.1	GO:0042627	chylomicron(GO:0042627)
6.0	18.0	GO:1990423	RZZ complex(GO:1990423)
6.0	221.3	GO:0030173	integral component of Golgi membrane(GO:0030173)
5.9	17.8	GO:0030312	external encapsulating structure(GO:0030312)
5.9	437.6	GO:0005643	nuclear pore(GO:0005643)
5.9	41.3	GO:0001520	outer dense fiber(GO:0001520)
5.8	5.8	GO:1904724	tertiary granule lumen(GO:1904724)
5.7	435.5	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
5.7	260.0	GO:0030670	phagocytic vesicle membrane(GO:0030670)
5.6	84.0	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
5.5	60.8	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
5.5	27.3	GO:0031264	death-inducing signaling complex(GO:0031264)
5.4	75.8	GO:0043189	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
5.3	21.1	GO:0071595	Nem1-Spo7 phosphatase complex(GO:0071595)
5.2	46.9	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
5.1	77.2	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
5.1	15.4	GO:1990038	glial cytoplasmic inclusion(GO:0097409) classical Lewy body(GO:0097414) Lewy neurite(GO:0097462) Lewy body corona(GO:1990038)
5.1	56.2	GO:0070449	elongin complex(GO:0070449)
5.1	86.8	GO:0035631	CD40 receptor complex(GO:0035631)
5.1	15.2	GO:1902636	kinociliary basal body(GO:1902636)
4.9	14.7	GO:0098576	lumenal side of membrane(GO:0098576)
4.8	53.2	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
4.8	14.5	GO:0033167	ARC complex(GO:0033167)
4.8	28.8	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
4.8	23.8	GO:0005839	proteasome core complex(GO:0005839)
4.7	32.9	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
4.7	233.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
4.6	36.7	GO:0032010	phagolysosome(GO:0032010)
4.5	22.7	GO:0033553	rDNA heterochromatin(GO:0033553)
4.5	45.4	GO:0001891	phagocytic cup(GO:0001891)
4.5	237.1	GO:0005840	ribosome(GO:0005840)
4.5	31.3	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
4.5	107.1	GO:0032592	integral component of mitochondrial membrane(GO:0032592)
4.5	303.2	GO:0005637	nuclear inner membrane(GO:0005637)
4.4	605.0	GO:0101002	ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
4.4	35.5	GO:0097413	Lewy body(GO:0097413)
4.4	382.7	GO:0005758	mitochondrial intermembrane space(GO:0005758)
4.3	13.0	GO:0035517	PR-DUB complex(GO:0035517)
4.3	34.2	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
4.2	41.9	GO:0032585	multivesicular body membrane(GO:0032585)
4.2	25.1	GO:0031414	N-terminal protein acetyltransferase complex(GO:0031414)
4.2	20.8	GO:0005943	phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
4.1	8.2	GO:0005726	perichromatin fibrils(GO:0005726)
4.1	20.4	GO:0030896	checkpoint clamp complex(GO:0030896)
4.1	20.4	GO:0000346	transcription export complex(GO:0000346)
4.0	52.2	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
4.0	39.8	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
3.9	11.7	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
3.9	11.6	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
3.8	23.0	GO:0032279	asymmetric synapse(GO:0032279)
3.8	546.6	GO:0005903	brush border(GO:0005903)
3.8	41.4	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
3.7	1391.7	GO:0016607	nuclear speck(GO:0016607)
3.7	62.5	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
3.7	36.7	GO:0035861	site of double-strand break(GO:0035861)
3.6	40.1	GO:0035692	macrophage migration inhibitory factor receptor complex(GO:0035692)
3.6	14.6	GO:0022624	proteasome accessory complex(GO:0022624)
3.6	7.3	GO:0000153	cytoplasmic ubiquitin ligase complex(GO:0000153)
3.6	101.7	GO:0005657	replication fork(GO:0005657)
3.5	187.2	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
3.4	13.8	GO:0034669	integrin alpha4-beta7 complex(GO:0034669)
3.4	365.5	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
3.4	10.1	GO:0005873	plus-end kinesin complex(GO:0005873)
3.4	47.1	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
3.3	320.4	GO:0042470	melanosome(GO:0042470) pigment granule(GO:0048770)
3.3	171.6	GO:0005871	kinesin complex(GO:0005871)
3.3	110.9	GO:0008180	COP9 signalosome(GO:0008180)
3.2	32.4	GO:0005964	phosphorylase kinase complex(GO:0005964)
3.2	25.9	GO:0002169	3-methylcrotonyl-CoA carboxylase complex, mitochondrial(GO:0002169) methylcrotonoyl-CoA carboxylase complex(GO:1905202)
3.2	6.5	GO:0070419	nonhomologous end joining complex(GO:0070419)
3.2	6.4	GO:0002079	inner acrosomal membrane(GO:0002079)
3.2	9.6	GO:0005745	m-AAA complex(GO:0005745)
3.2	3.2	GO:0070195	growth hormone receptor complex(GO:0070195)
3.1	72.4	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
3.1	6.2	GO:0019815	B cell receptor complex(GO:0019815)
3.0	36.3	GO:0031528	microvillus membrane(GO:0031528)
3.0	47.7	GO:0000502	proteasome complex(GO:0000502)
3.0	8.9	GO:0071144	SMAD2-SMAD3 protein complex(GO:0071144)
3.0	20.7	GO:0070652	HAUS complex(GO:0070652)
2.9	20.3	GO:0030057	desmosome(GO:0030057)
2.8	2.8	GO:0070381	endosome to plasma membrane transport vesicle(GO:0070381)
2.8	39.8	GO:0000812	Swr1 complex(GO:0000812)
2.8	36.9	GO:0016600	flotillin complex(GO:0016600)
2.8	48.0	GO:0002102	podosome(GO:0002102)
2.7	658.4	GO:0019866	organelle inner membrane(GO:0019866)
2.7	32.4	GO:0070938	contractile ring(GO:0070938)
2.7	43.1	GO:0031932	TORC2 complex(GO:0031932) TOR complex(GO:0038201)
2.7	13.4	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
2.7	2.7	GO:0034667	integrin alpha3-beta1 complex(GO:0034667)
2.7	10.6	GO:0005876	spindle microtubule(GO:0005876)
2.6	10.5	GO:0044307	dendritic branch(GO:0044307)
2.6	49.2	GO:0000407	pre-autophagosomal structure(GO:0000407)
2.5	15.3	GO:0048188	Set1C/COMPASS complex(GO:0048188)
2.5	325.9	GO:0005741	mitochondrial outer membrane(GO:0005741)
2.5	211.2	GO:0070821	tertiary granule membrane(GO:0070821)
2.5	15.2	GO:0097451	astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
2.5	27.6	GO:0000124	SAGA complex(GO:0000124)
2.5	318.5	GO:0000793	condensed chromosome(GO:0000793)
2.5	20.0	GO:0000930	gamma-tubulin complex(GO:0000930)
2.5	7.4	GO:0071439	clathrin complex(GO:0071439)
2.5	4.9	GO:0032059	bleb(GO:0032059)
2.4	7.3	GO:0071750	dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752)
2.4	17.0	GO:0030677	ribonuclease P complex(GO:0030677)
2.4	2.4	GO:1990075	periciliary membrane compartment(GO:1990075)
2.4	7.2	GO:0044754	autolysosome(GO:0044754)
2.4	92.1	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
2.3	2.3	GO:0043073	germ cell nucleus(GO:0043073)
2.3	58.0	GO:0000776	kinetochore(GO:0000776)
2.3	4.6	GO:0031088	platelet dense granule membrane(GO:0031088)
2.3	173.3	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
2.3	50.5	GO:0016327	apicolateral plasma membrane(GO:0016327)
2.3	38.8	GO:0035580	specific granule lumen(GO:0035580)
2.3	6.8	GO:0017109	glutamate-cysteine ligase complex(GO:0017109)
2.2	15.5	GO:0070822	Sin3-type complex(GO:0070822)
2.2	30.8	GO:0005719	nuclear euchromatin(GO:0005719)
2.2	21.8	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
2.2	134.2	GO:0032580	Golgi cisterna membrane(GO:0032580)
2.2	2.2	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
2.1	10.6	GO:1902555	endoribonuclease complex(GO:1902555)
2.1	8.3	GO:0005965	protein farnesyltransferase complex(GO:0005965)
2.0	66.9	GO:0031258	lamellipodium membrane(GO:0031258)
2.0	8.0	GO:0032433	filopodium tip(GO:0032433)
2.0	2.0	GO:0044308	axonal spine(GO:0044308)
2.0	46.1	GO:0045335	phagocytic vesicle(GO:0045335)
2.0	7.9	GO:0043541	UDP-N-acetylglucosamine transferase complex(GO:0043541)
1.9	18.9	GO:0051233	spindle midzone(GO:0051233)
1.9	15.0	GO:0030056	hemidesmosome(GO:0030056)
1.8	24.8	GO:0000145	exocyst(GO:0000145)
1.8	5.3	GO:1990393	3M complex(GO:1990393)
1.7	13.9	GO:0070852	cell body fiber(GO:0070852)
1.7	122.0	GO:0016459	myosin complex(GO:0016459)
1.6	486.4	GO:0005635	nuclear envelope(GO:0005635)
1.6	7.8	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
1.6	4.7	GO:0032389	MutLalpha complex(GO:0032389)
1.5	3.1	GO:0097431	mitotic spindle pole(GO:0097431)
1.5	54.8	GO:0000784	nuclear chromosome, telomeric region(GO:0000784)
1.5	82.0	GO:0005778	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
1.5	11.9	GO:0008385	IkappaB kinase complex(GO:0008385)
1.5	71.8	GO:0005795	Golgi stack(GO:0005795)
1.4	54.5	GO:0045095	keratin filament(GO:0045095)
1.4	5.7	GO:0048179	activin receptor complex(GO:0048179)
1.4	4.2	GO:0005588	collagen type V trimer(GO:0005588)
1.4	123.1	GO:0017053	transcriptional repressor complex(GO:0017053)
1.3	10.7	GO:0061689	tricellular tight junction(GO:0061689)
1.3	45.1	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
1.3	6.6	GO:0005896	interleukin-6 receptor complex(GO:0005896)
1.3	151.7	GO:1990904	ribonucleoprotein complex(GO:1990904)
1.3	2.6	GO:0000788	nuclear nucleosome(GO:0000788)
1.3	8.8	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
1.3	63.0	GO:0042571	immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
1.3	6.3	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
1.2	78.0	GO:0097517	stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
1.2	1.2	GO:0097449	astrocyte projection(GO:0097449)
1.1	22.2	GO:0043205	microfibril(GO:0001527) fibril(GO:0043205)
1.1	4.4	GO:0019867	outer membrane(GO:0019867)
1.1	57.4	GO:0031966	mitochondrial membrane(GO:0031966)
1.1	2579.4	GO:0070062	extracellular exosome(GO:0070062)
1.0	73.5	GO:0000922	spindle pole(GO:0000922)
0.9	6.3	GO:0031941	filamentous actin(GO:0031941)
0.9	2.7	GO:0030936	collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.9	10.6	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.9	10.3	GO:0044216	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.9	2.6	GO:0042613	MHC class II protein complex(GO:0042613)
0.8	3.9	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.8	24.0	GO:0016235	aggresome(GO:0016235)
0.8	23.9	GO:0045171	intercellular bridge(GO:0045171)
0.8	1.5	GO:0072487	MSL complex(GO:0072487)
0.6	3.7	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.6	34.9	GO:0005913	cell-cell adherens junction(GO:0005913)
0.6	25.8	GO:0005776	autophagosome(GO:0005776)
0.6	5.3	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.5	1.0	GO:1990682	CSF1-CSF1R complex(GO:1990682)
0.4	7.8	GO:0042581	specific granule(GO:0042581)
0.4	4.1	GO:0005605	basal lamina(GO:0005605)
0.3	1.4	GO:0001739	sex chromatin(GO:0001739)
0.3	2.0	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.3	0.6	GO:0031089	platelet dense granule lumen(GO:0031089)
0.3	0.8	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.2	0.7	GO:0043512	inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.2	1.8	GO:0044292	dendrite terminus(GO:0044292)
0.2	0.6	GO:0033150	perinuclear theca(GO:0033011) cytoskeletal calyx(GO:0033150)
0.2	4.6	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	1.4	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.1	0.5	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.4	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
88.7	266.2	GO:0098808	mRNA cap binding(GO:0098808)
79.4	238.2	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
64.9	519.1	GO:0070990	snRNP binding(GO:0070990)
59.3	177.8	GO:0044713	GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693)
56.9	113.8	GO:0061628	H3K27me3 modified histone binding(GO:0061628)
54.2	162.6	GO:0034511	U3 snoRNA binding(GO:0034511)
52.0	363.9	GO:0030620	U2 snRNA binding(GO:0030620)
48.4	532.8	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
44.5	1247.0	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
44.1	220.6	GO:0003920	GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
43.4	130.3	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
42.5	170.2	GO:0045127	N-acetylglucosamine kinase activity(GO:0045127)
38.7	309.6	GO:0030621	U4 snRNA binding(GO:0030621)
38.6	347.6	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
37.7	376.8	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
36.1	252.8	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
35.4	177.0	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
34.6	241.9	GO:0032217	riboflavin transporter activity(GO:0032217)
34.1	102.4	GO:0005046	KDEL sequence binding(GO:0005046)
32.3	258.0	GO:0015450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
32.2	96.6	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
31.8	254.4	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
31.7	126.8	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
31.6	189.8	GO:0043023	ribosomal large subunit binding(GO:0043023)
30.6	122.5	GO:0042134	rRNA primary transcript binding(GO:0042134)
30.1	120.3	GO:0016230	sphingomyelin phosphodiesterase activator activity(GO:0016230)
29.4	264.7	GO:0055104	ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
27.1	27.1	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
27.0	81.0	GO:0070259	tyrosyl-DNA phosphodiesterase activity(GO:0070259)
26.8	80.4	GO:0031753	endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
26.3	78.8	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
26.2	183.5	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
26.0	104.1	GO:0002060	purine nucleobase binding(GO:0002060)
25.9	155.3	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
25.5	178.4	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
24.3	97.4	GO:0008311	double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
24.0	144.2	GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
23.9	23.9	GO:0032405	MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
23.7	142.5	GO:0005047	signal recognition particle binding(GO:0005047)
23.5	70.4	GO:0001069	regulatory region RNA binding(GO:0001069)
23.0	69.1	GO:0030156	benzodiazepine receptor binding(GO:0030156)
23.0	459.8	GO:0042609	CD4 receptor binding(GO:0042609)
22.7	22.7	GO:0070363	mitochondrial light strand promoter sense binding(GO:0070363)
22.4	134.7	GO:0004594	pantothenate kinase activity(GO:0004594)
22.4	246.6	GO:0004576	oligosaccharyl transferase activity(GO:0004576)
22.2	110.8	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
22.0	88.0	GO:0004360	glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
21.9	197.0	GO:0035174	histone serine kinase activity(GO:0035174)
21.5	451.5	GO:0043495	protein anchor(GO:0043495)
21.1	168.4	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
20.9	125.4	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
20.8	104.0	GO:0047179	platelet-activating factor acetyltransferase activity(GO:0047179)
20.8	145.5	GO:0061133	endopeptidase activator activity(GO:0061133)
20.4	40.9	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
20.4	142.9	GO:0000295	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
20.3	81.3	GO:0098770	FBXO family protein binding(GO:0098770)
20.2	121.4	GO:0047134	protein-disulfide reductase activity(GO:0047134)
20.2	60.6	GO:0003974	UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
20.1	160.9	GO:1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
20.1	220.8	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
20.0	120.2	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
19.9	59.6	GO:0004170	dUTP diphosphatase activity(GO:0004170)
19.7	1316.7	GO:0003743	translation initiation factor activity(GO:0003743)
19.6	137.4	GO:0016531	copper chaperone activity(GO:0016531)
19.6	58.8	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
19.3	77.3	GO:0033677	DNA/RNA helicase activity(GO:0033677)
19.1	57.4	GO:0004492	methylmalonyl-CoA decarboxylase activity(GO:0004492)
18.9	56.6	GO:0070538	oleic acid binding(GO:0070538)
18.7	56.2	GO:0004730	pseudouridylate synthase activity(GO:0004730)
18.7	56.2	GO:0042947	glucoside transmembrane transporter activity(GO:0042947)
18.6	55.8	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
18.5	333.1	GO:0001055	RNA polymerase II activity(GO:0001055)
18.4	110.3	GO:0004704	NF-kappaB-inducing kinase activity(GO:0004704)
17.8	142.5	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
17.0	203.9	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
17.0	288.3	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
17.0	50.9	GO:0016422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
16.8	84.2	GO:0019788	NEDD8 transferase activity(GO:0019788)
16.8	134.7	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
16.8	117.6	GO:0015266	protein channel activity(GO:0015266)
16.6	33.2	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
16.3	260.1	GO:0008179	adenylate cyclase binding(GO:0008179)
16.2	48.5	GO:0004307	ethanolaminephosphotransferase activity(GO:0004307)
16.1	48.4	GO:0000033	alpha-1,3-mannosyltransferase activity(GO:0000033)
16.1	80.4	GO:0047844	deoxycytidine deaminase activity(GO:0047844)
16.0	47.9	GO:0071933	Arp2/3 complex binding(GO:0071933)
15.7	78.7	GO:0034647	histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
15.7	439.8	GO:0017056	structural constituent of nuclear pore(GO:0017056)
15.7	62.7	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
15.7	47.0	GO:0004132	dCMP deaminase activity(GO:0004132)
15.6	124.8	GO:0050733	RS domain binding(GO:0050733)
15.5	450.8	GO:0017025	TBP-class protein binding(GO:0017025)
15.5	46.4	GO:0009041	uridylate kinase activity(GO:0009041)
15.4	725.7	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
15.0	134.9	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
15.0	89.7	GO:0035500	MH2 domain binding(GO:0035500)
14.9	74.6	GO:0016936	galactoside binding(GO:0016936)
14.9	89.3	GO:0004310	farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
14.9	74.3	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
14.8	29.6	GO:0017057	6-phosphogluconolactonase activity(GO:0017057)
14.7	44.2	GO:0004766	spermidine synthase activity(GO:0004766)
14.7	175.9	GO:0031386	protein tag(GO:0031386)
14.7	44.0	GO:0031403	lithium ion binding(GO:0031403)
14.6	58.5	GO:0003883	CTP synthase activity(GO:0003883)
14.5	2888.9	GO:0003735	structural constituent of ribosome(GO:0003735)
14.2	71.0	GO:0030348	syntaxin-3 binding(GO:0030348)
14.1	155.6	GO:0004673	protein histidine kinase activity(GO:0004673)
14.1	28.1	GO:0008169	C-methyltransferase activity(GO:0008169)
14.1	98.5	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
14.0	28.0	GO:0001129	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
13.9	27.9	GO:0000995	transcription factor activity, core RNA polymerase III binding(GO:0000995)
13.9	97.1	GO:0060698	endoribonuclease inhibitor activity(GO:0060698)
13.8	207.6	GO:0000339	RNA cap binding(GO:0000339)
13.7	41.2	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
13.7	27.4	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
13.5	67.5	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
13.3	66.6	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
13.3	106.4	GO:0044388	small protein activating enzyme binding(GO:0044388)
13.3	66.5	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
13.3	39.8	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
13.2	52.6	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
12.9	64.6	GO:0032564	adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
12.8	38.3	GO:0004566	beta-glucuronidase activity(GO:0004566)
12.7	38.1	GO:0004450	isocitrate dehydrogenase (NADP+) activity(GO:0004450)
12.7	38.1	GO:0055100	adiponectin binding(GO:0055100)
12.7	38.1	GO:0033981	D-dopachrome decarboxylase activity(GO:0033981)
12.7	291.1	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
12.6	50.5	GO:0004743	pyruvate kinase activity(GO:0004743)
12.5	224.2	GO:0016018	cyclosporin A binding(GO:0016018)
12.5	62.3	GO:0089720	caspase binding(GO:0089720)
12.3	98.7	GO:0008097	5S rRNA binding(GO:0008097)
12.3	135.0	GO:0016004	phospholipase activator activity(GO:0016004)
12.1	121.4	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
12.0	12.0	GO:0035243	protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
12.0	59.9	GO:0043024	ribosomal small subunit binding(GO:0043024)
12.0	35.9	GO:0050613	delta14-sterol reductase activity(GO:0050613)
11.9	95.0	GO:1990825	sequence-specific mRNA binding(GO:1990825)
11.8	47.4	GO:0019107	glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
11.8	449.1	GO:0005123	death receptor binding(GO:0005123)
11.8	82.6	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
11.7	70.4	GO:0048408	epidermal growth factor binding(GO:0048408)
11.7	70.4	GO:0016748	succinyltransferase activity(GO:0016748)
11.7	82.0	GO:0030369	ICAM-3 receptor activity(GO:0030369)
11.6	93.2	GO:0019784	NEDD8-specific protease activity(GO:0019784)
11.6	93.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
11.5	80.7	GO:0051021	GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
11.5	34.6	GO:0030337	DNA polymerase processivity factor activity(GO:0030337)
11.5	46.0	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
11.5	275.5	GO:0031369	translation initiation factor binding(GO:0031369)
11.5	332.1	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
11.4	34.1	GO:0045131	pre-mRNA branch point binding(GO:0045131)
11.4	79.5	GO:0050815	phosphoserine binding(GO:0050815)
11.3	45.3	GO:0047676	arachidonate-CoA ligase activity(GO:0047676)
11.3	67.9	GO:0004301	epoxide hydrolase activity(GO:0004301)
11.3	11.3	GO:0008426	protein kinase C inhibitor activity(GO:0008426)
11.3	45.1	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
11.3	33.8	GO:0004315	3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
11.1	11.1	GO:0051731	polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
11.1	143.8	GO:0030515	snoRNA binding(GO:0030515)
11.0	297.1	GO:0008187	poly-pyrimidine tract binding(GO:0008187)
11.0	417.6	GO:0070577	lysine-acetylated histone binding(GO:0070577)
11.0	76.8	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
11.0	460.5	GO:0046966	thyroid hormone receptor binding(GO:0046966)
10.9	186.0	GO:0050786	RAGE receptor binding(GO:0050786)
10.9	32.6	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
10.8	54.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
10.5	42.0	GO:0001849	complement component C1q binding(GO:0001849)
10.4	31.3	GO:0032089	NACHT domain binding(GO:0032089)
10.4	41.6	GO:0033897	ribonuclease T2 activity(GO:0033897)
10.3	31.0	GO:0016454	serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
10.3	195.1	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
10.3	82.0	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
10.2	40.8	GO:0061676	importin-alpha family protein binding(GO:0061676)
10.2	20.4	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
10.2	254.0	GO:0005095	GTPase inhibitor activity(GO:0005095)
10.1	60.8	GO:0048256	flap endonuclease activity(GO:0048256)
10.1	40.3	GO:0032184	SUMO polymer binding(GO:0032184)
10.0	29.9	GO:0008670	2,4-dienoyl-CoA reductase (NADPH) activity(GO:0008670)
9.9	29.8	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
9.8	39.4	GO:0015119	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
9.8	235.7	GO:0070064	proline-rich region binding(GO:0070064)
9.8	29.4	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
9.7	185.0	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
9.7	38.9	GO:0030107	HLA-A specific inhibitory MHC class I receptor activity(GO:0030107)
9.7	58.4	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
9.7	194.3	GO:0032036	myosin heavy chain binding(GO:0032036)
9.7	38.7	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
9.7	29.0	GO:0070991	medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
9.6	347.3	GO:0001671	ATPase activator activity(GO:0001671)
9.6	105.7	GO:0019869	chloride channel inhibitor activity(GO:0019869)
9.6	19.1	GO:0008177	succinate dehydrogenase (ubiquinone) activity(GO:0008177)
9.6	47.8	GO:0004774	succinate-CoA ligase activity(GO:0004774)
9.4	216.4	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
9.4	103.4	GO:0046790	virion binding(GO:0046790)
9.3	112.2	GO:0008143	poly(A) binding(GO:0008143)
9.3	56.1	GO:0043120	tumor necrosis factor binding(GO:0043120)
9.3	121.4	GO:0017070	U6 snRNA binding(GO:0017070)
9.3	93.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
9.2	27.7	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
9.2	36.7	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
9.2	54.9	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
9.2	45.8	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
9.1	45.5	GO:0043208	glycosphingolipid binding(GO:0043208)
9.0	18.1	GO:0000403	Y-form DNA binding(GO:0000403)
9.0	153.0	GO:0048027	mRNA 5'-UTR binding(GO:0048027)
8.9	26.8	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
8.9	44.6	GO:0004337	dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
8.8	79.3	GO:0016842	amidine-lyase activity(GO:0016842)
8.5	25.6	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
8.5	50.7	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
8.4	58.9	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
8.4	42.0	GO:0004920	interleukin-10 receptor activity(GO:0004920)
8.4	142.4	GO:0051400	BH domain binding(GO:0051400)
8.4	217.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
8.3	66.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
8.2	393.6	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
8.0	24.0	GO:0005010	insulin-like growth factor-activated receptor activity(GO:0005010)
8.0	224.0	GO:0042288	MHC class I protein binding(GO:0042288)
8.0	63.9	GO:0019237	centromeric DNA binding(GO:0019237)
7.9	39.5	GO:0031871	proteinase activated receptor binding(GO:0031871)
7.9	15.8	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
7.9	23.6	GO:0032090	Pyrin domain binding(GO:0032090)
7.9	39.4	GO:0051998	carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
7.8	101.4	GO:0043138	3'-5' DNA helicase activity(GO:0043138)
7.8	23.3	GO:0047315	kynurenine-glyoxylate transaminase activity(GO:0047315)
7.6	91.6	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
7.6	22.9	GO:0044594	3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity(GO:0033989) 17-beta-hydroxysteroid dehydrogenase (NAD+) activity(GO:0044594)
7.6	60.9	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
7.6	45.6	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
7.6	22.7	GO:0016784	3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
7.6	15.1	GO:0008469	histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
7.5	22.6	GO:0033699	DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
7.5	97.7	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
7.5	164.9	GO:0043021	ribonucleoprotein complex binding(GO:0043021)
7.4	29.7	GO:0003963	RNA-3'-phosphate cyclase activity(GO:0003963)
7.3	22.0	GO:0097677	STAT family protein binding(GO:0097677)
7.3	43.9	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
7.2	21.7	GO:0050528	acyloxyacyl hydrolase activity(GO:0050528)
7.1	21.4	GO:0008534	oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
7.1	142.6	GO:0048156	tau protein binding(GO:0048156)
7.1	7.1	GO:0044378	non-sequence-specific DNA binding, bending(GO:0044378)
7.0	56.0	GO:0030274	LIM domain binding(GO:0030274)
7.0	13.9	GO:0004167	dopachrome isomerase activity(GO:0004167)
7.0	55.6	GO:0070087	chromo shadow domain binding(GO:0070087)
7.0	20.9	GO:0080023	3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
6.9	20.8	GO:0047756	N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537) chondroitin 4-sulfotransferase activity(GO:0047756)
6.9	311.2	GO:0050699	WW domain binding(GO:0050699)
6.9	27.5	GO:0015307	drug:proton antiporter activity(GO:0015307)
6.9	34.3	GO:0004464	leukotriene-C4 synthase activity(GO:0004464)
6.9	20.6	GO:0071566	UFM1 activating enzyme activity(GO:0071566)
6.7	107.8	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
6.7	127.7	GO:0043422	protein kinase B binding(GO:0043422)
6.7	33.6	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
6.7	349.2	GO:0031593	polyubiquitin binding(GO:0031593)
6.7	93.8	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
6.7	33.5	GO:0030613	oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
6.6	39.9	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
6.6	33.1	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
6.6	131.6	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
6.5	327.1	GO:0031491	nucleosome binding(GO:0031491)
6.5	32.7	GO:0036033	mediator complex binding(GO:0036033)
6.5	39.2	GO:0010997	anaphase-promoting complex binding(GO:0010997)
6.5	651.3	GO:0003697	single-stranded DNA binding(GO:0003697)
6.5	19.5	GO:0004912	interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
6.4	154.6	GO:0008135	translation factor activity, RNA binding(GO:0008135)
6.3	19.0	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
6.3	12.6	GO:0046979	TAP2 binding(GO:0046979)
6.2	149.8	GO:0031489	myosin V binding(GO:0031489)
6.2	18.5	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
6.2	18.5	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
6.1	43.0	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
6.1	18.4	GO:0008466	glycogenin glucosyltransferase activity(GO:0008466)
6.1	18.3	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
6.1	18.2	GO:0002046	opsin binding(GO:0002046)
6.1	249.0	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
6.1	6.1	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
6.0	47.9	GO:0017128	phospholipid scramblase activity(GO:0017128)
6.0	24.0	GO:0000026	alpha-1,2-mannosyltransferase activity(GO:0000026)
5.9	249.8	GO:0017091	AU-rich element binding(GO:0017091)
5.9	17.8	GO:0008320	protein transmembrane transporter activity(GO:0008320)
5.9	35.3	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
5.9	23.4	GO:0004448	isocitrate dehydrogenase activity(GO:0004448)
5.8	46.3	GO:0004000	adenosine deaminase activity(GO:0004000)
5.8	46.3	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
5.8	23.1	GO:0048039	ubiquinone binding(GO:0048039)
5.7	17.2	GO:0003860	3-hydroxyisobutyryl-CoA hydrolase activity(GO:0003860)
5.7	39.9	GO:0035613	RNA stem-loop binding(GO:0035613)
5.7	17.1	GO:0032138	single base insertion or deletion binding(GO:0032138)
5.7	17.0	GO:0015140	malate transmembrane transporter activity(GO:0015140)
5.6	28.1	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
5.6	28.0	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
5.6	16.8	GO:0017077	oxidative phosphorylation uncoupler activity(GO:0017077)
5.6	61.5	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
5.6	22.3	GO:0047429	nucleoside-triphosphate diphosphatase activity(GO:0047429)
5.6	38.9	GO:0035197	siRNA binding(GO:0035197)
5.6	16.7	GO:0033858	N-acetylgalactosamine kinase activity(GO:0033858)
5.5	332.5	GO:0019003	GDP binding(GO:0019003)
5.5	82.5	GO:0015215	nucleotide transmembrane transporter activity(GO:0015215)
5.5	38.3	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
5.4	21.7	GO:0004348	glucosylceramidase activity(GO:0004348)
5.4	10.8	GO:0004906	interferon-gamma receptor activity(GO:0004906)
5.4	16.1	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
5.4	85.6	GO:0097602	cullin family protein binding(GO:0097602)
5.3	15.9	GO:0008330	protein tyrosine/threonine phosphatase activity(GO:0008330)
5.3	21.2	GO:0070404	NADH binding(GO:0070404)
5.3	37.1	GO:0004459	lactate dehydrogenase activity(GO:0004457) L-lactate dehydrogenase activity(GO:0004459)
5.3	15.9	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
5.3	15.9	GO:0000822	inositol hexakisphosphate binding(GO:0000822)
5.3	36.9	GO:0016681	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
5.3	36.8	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
5.2	162.6	GO:0044183	protein binding involved in protein folding(GO:0044183)
5.2	198.0	GO:0005484	SNAP receptor activity(GO:0005484)
5.2	46.9	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
5.2	5.2	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
5.2	25.8	GO:0019776	Atg8 ligase activity(GO:0019776)
5.1	15.4	GO:0052836	inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
5.1	25.5	GO:0004066	asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
5.1	311.5	GO:0043130	ubiquitin binding(GO:0043130)
5.1	81.6	GO:1901612	cardiolipin binding(GO:1901612)
5.1	55.8	GO:0019534	toxin transporter activity(GO:0019534)
5.0	85.7	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
5.0	74.8	GO:0019211	phosphatase activator activity(GO:0019211)
5.0	99.5	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
4.9	34.4	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
4.9	19.6	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
4.9	34.3	GO:0015288	porin activity(GO:0015288)
4.8	256.1	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
4.8	28.8	GO:0001054	RNA polymerase I activity(GO:0001054)
4.8	67.2	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
4.8	33.5	GO:0050700	CARD domain binding(GO:0050700)
4.7	9.4	GO:0008263	pyrimidine-specific mismatch base pair DNA N-glycosylase activity(GO:0008263)
4.7	51.7	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
4.7	42.2	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
4.7	37.4	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
4.7	79.1	GO:0004550	nucleoside diphosphate kinase activity(GO:0004550)
4.6	60.2	GO:0008327	methyl-CpG binding(GO:0008327)
4.6	69.0	GO:0008157	protein phosphatase 1 binding(GO:0008157)
4.6	46.0	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
4.6	36.7	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
4.6	1704.1	GO:0045296	cadherin binding(GO:0045296)
4.6	27.4	GO:1990763	arrestin family protein binding(GO:1990763)
4.5	36.2	GO:0019212	phosphatase inhibitor activity(GO:0019212)
4.4	13.3	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
4.4	40.0	GO:0032051	clathrin light chain binding(GO:0032051)
4.4	13.3	GO:0031996	thioesterase binding(GO:0031996)
4.4	39.6	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
4.4	13.1	GO:0016314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
4.3	446.9	GO:0008565	protein transporter activity(GO:0008565)
4.3	17.2	GO:0032557	pyrimidine ribonucleotide binding(GO:0032557)
4.3	12.8	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
4.3	25.6	GO:0004849	uridine kinase activity(GO:0004849)
4.3	51.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
4.2	782.5	GO:0051015	actin filament binding(GO:0051015)
4.2	38.0	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
4.2	25.3	GO:0043560	insulin receptor substrate binding(GO:0043560)
4.2	12.6	GO:0005136	interleukin-4 receptor binding(GO:0005136)
4.2	16.8	GO:0017159	pantetheine hydrolase activity(GO:0017159)
4.2	12.6	GO:0016979	lipoate-protein ligase activity(GO:0016979)
4.2	124.6	GO:0019198	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
4.2	12.5	GO:0004958	prostaglandin F receptor activity(GO:0004958)
4.2	265.7	GO:0008235	metalloexopeptidase activity(GO:0008235)
4.1	70.1	GO:0004697	protein kinase C activity(GO:0004697)
4.1	516.5	GO:0047485	protein N-terminus binding(GO:0047485)
4.1	40.7	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
4.0	28.3	GO:0034452	dynactin binding(GO:0034452)
4.0	12.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
3.9	19.7	GO:1990226	histone methyltransferase binding(GO:1990226)
3.9	7.8	GO:0010698	acetyltransferase activator activity(GO:0010698)
3.9	97.8	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
3.9	69.6	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
3.9	85.0	GO:0036442	hydrogen-exporting ATPase activity(GO:0036442) ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
3.8	61.4	GO:0005537	mannose binding(GO:0005537)
3.8	106.3	GO:0000993	RNA polymerase II core binding(GO:0000993)
3.8	41.3	GO:0019213	deacetylase activity(GO:0019213)
3.7	11.2	GO:0016154	thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154)
3.7	29.7	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
3.7	11.1	GO:0004418	hydroxymethylbilane synthase activity(GO:0004418)
3.7	18.4	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
3.6	10.9	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
3.6	10.9	GO:0004525	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
3.6	14.3	GO:0050211	procollagen galactosyltransferase activity(GO:0050211)
3.6	7.1	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
3.4	3.4	GO:0019239	deaminase activity(GO:0019239)
3.4	17.1	GO:0003835	beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
3.4	23.7	GO:0042978	ornithine decarboxylase activator activity(GO:0042978)
3.3	13.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
3.2	32.4	GO:0004689	phosphorylase kinase activity(GO:0004689)
3.2	25.9	GO:0004485	methylcrotonoyl-CoA carboxylase activity(GO:0004485)
3.2	25.7	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
3.2	31.8	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
3.2	6.3	GO:0008384	IkappaB kinase activity(GO:0008384)
3.2	34.8	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
3.2	22.1	GO:0001165	RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
3.1	12.5	GO:0070320	inward rectifier potassium channel inhibitor activity(GO:0070320)
3.1	15.6	GO:0035673	oligopeptide transmembrane transporter activity(GO:0035673)
3.1	18.7	GO:0045505	dynein intermediate chain binding(GO:0045505)
3.1	89.6	GO:0042974	retinoic acid receptor binding(GO:0042974)
3.1	27.7	GO:0032050	clathrin heavy chain binding(GO:0032050)
3.1	18.4	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
3.1	12.3	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
3.0	9.1	GO:0033765	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
3.0	125.1	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
3.0	144.7	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
3.0	38.4	GO:0015926	glucosidase activity(GO:0015926)
2.9	11.8	GO:0004420	hydroxymethylglutaryl-CoA reductase (NADPH) activity(GO:0004420) hydroxymethylglutaryl-CoA reductase activity(GO:0042282)
2.9	17.5	GO:0003796	lysozyme activity(GO:0003796)
2.9	25.9	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
2.8	31.2	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
2.8	19.8	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
2.8	5.7	GO:0016418	S-acetyltransferase activity(GO:0016418)
2.8	11.3	GO:0004647	phosphoserine phosphatase activity(GO:0004647)
2.8	47.8	GO:0019992	diacylglycerol binding(GO:0019992)
2.8	59.0	GO:0071889	14-3-3 protein binding(GO:0071889)
2.8	8.4	GO:1990254	keratin filament binding(GO:1990254)
2.8	8.4	GO:0042799	histone methyltransferase activity (H4-K20 specific)(GO:0042799)
2.7	13.7	GO:0008094	DNA-dependent ATPase activity(GO:0008094)
2.7	16.4	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453)
2.7	19.1	GO:0004470	malic enzyme activity(GO:0004470)
2.7	29.9	GO:0004985	opioid receptor activity(GO:0004985)
2.7	35.0	GO:0004303	estradiol 17-beta-dehydrogenase activity(GO:0004303)
2.7	13.5	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
2.7	37.5	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
2.7	8.0	GO:0005534	galactose binding(GO:0005534) disaccharide binding(GO:0048030)
2.7	13.3	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
2.6	34.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
2.6	86.5	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
2.6	41.0	GO:0031702	angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
2.6	10.2	GO:0003960	NADPH:quinone reductase activity(GO:0003960)
2.6	10.2	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
2.6	35.8	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
2.5	60.4	GO:0031210	phosphatidylcholine binding(GO:0031210)
2.5	45.2	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
2.5	5.0	GO:0008988	rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
2.5	10.0	GO:0004430	1-phosphatidylinositol 4-kinase activity(GO:0004430)
2.4	2670.4	GO:0003723	RNA binding(GO:0003723)
2.4	9.6	GO:0000182	rDNA binding(GO:0000182)
2.4	31.0	GO:0003678	DNA helicase activity(GO:0003678)
2.3	30.3	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
2.3	9.2	GO:0034235	GPI anchor binding(GO:0034235)
2.3	6.8	GO:0004357	glutamate-cysteine ligase activity(GO:0004357)
2.2	20.2	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
2.2	35.6	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
2.2	13.1	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
2.2	4.4	GO:0051861	glycolipid binding(GO:0051861)
2.2	6.6	GO:0070119	ciliary neurotrophic factor binding(GO:0070119)
2.2	6.5	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
2.1	8.6	GO:0042834	peptidoglycan binding(GO:0042834)
2.1	19.0	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
2.1	4.2	GO:0045182	translation regulator activity(GO:0045182)
2.1	10.4	GO:0005134	interleukin-2 receptor binding(GO:0005134)
2.0	6.1	GO:0004772	sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
2.0	57.0	GO:0015002	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
2.0	18.2	GO:0004727	prenylated protein tyrosine phosphatase activity(GO:0004727)
2.0	67.0	GO:0016831	carboxy-lyase activity(GO:0016831)
2.0	9.8	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
1.9	13.5	GO:0034594	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) phosphatidylinositol trisphosphate phosphatase activity(GO:0034594)
1.9	5.7	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
1.9	5.7	GO:0036134	thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
1.9	47.0	GO:0001965	G-protein alpha-subunit binding(GO:0001965)
1.9	5.6	GO:0001226	RNA polymerase II transcription corepressor binding(GO:0001226)
1.9	13.0	GO:0016840	carbon-nitrogen lyase activity(GO:0016840)
1.8	7.4	GO:0047685	amine sulfotransferase activity(GO:0047685)
1.8	40.2	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
1.8	25.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
1.8	63.0	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
1.8	12.5	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
1.8	15.8	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
1.8	56.2	GO:0005540	hyaluronic acid binding(GO:0005540)
1.8	8.8	GO:0004771	sterol esterase activity(GO:0004771)
1.7	5.2	GO:0004466	long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
1.7	6.9	GO:0030898	actin-dependent ATPase activity(GO:0030898)
1.7	18.7	GO:0033130	acetylcholine receptor binding(GO:0033130)
1.7	5.0	GO:0008511	sodium:potassium:chloride symporter activity(GO:0008511)
1.6	4.9	GO:0035731	S-nitrosoglutathione binding(GO:0035730) dinitrosyl-iron complex binding(GO:0035731)
1.6	6.5	GO:0004905	type I interferon receptor activity(GO:0004905)
1.6	3.2	GO:0070324	thyroid hormone binding(GO:0070324)
1.6	23.7	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
1.6	12.5	GO:0016413	O-acetyltransferase activity(GO:0016413)
1.6	6.2	GO:0097617	annealing activity(GO:0097617)
1.6	172.9	GO:0042393	histone binding(GO:0042393)
1.5	67.0	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
1.5	9.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
1.5	10.3	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
1.4	4.3	GO:0000252	C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity(GO:0047012)
1.4	5.7	GO:0008428	ribonuclease inhibitor activity(GO:0008428)
1.4	1.4	GO:0005294	neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294)
1.4	5.7	GO:0003680	AT DNA binding(GO:0003680)
1.4	4.2	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
1.4	7.1	GO:0043274	phospholipase binding(GO:0043274)
1.4	19.5	GO:0043531	ADP binding(GO:0043531)
1.4	20.8	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
1.4	8.3	GO:0004645	phosphorylase activity(GO:0004645)
1.4	2.7	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
1.3	5.3	GO:0042608	T cell receptor binding(GO:0042608)
1.3	13.3	GO:0016814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
1.3	48.8	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
1.3	13.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
1.3	6.4	GO:0043426	MRF binding(GO:0043426)
1.3	7.6	GO:0047237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
1.2	14.8	GO:0005522	profilin binding(GO:0005522)
1.2	34.5	GO:0043236	laminin binding(GO:0043236)
1.2	39.0	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
1.2	3.7	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
1.2	8.5	GO:0051525	NFAT protein binding(GO:0051525)
1.2	16.8	GO:0032395	MHC class II receptor activity(GO:0032395)
1.2	3.6	GO:0004597	peptide-aspartate beta-dioxygenase activity(GO:0004597)
1.2	8.4	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
1.2	4.8	GO:0004074	biliverdin reductase activity(GO:0004074)
1.2	4.8	GO:0034186	apolipoprotein A-I binding(GO:0034186)
1.2	3.6	GO:0031626	beta-endorphin binding(GO:0031626)
1.2	5.9	GO:0052656	branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
1.2	4.6	GO:0016404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
1.1	15.7	GO:0005536	glucose binding(GO:0005536)
1.1	3.4	GO:0004465	lipoprotein lipase activity(GO:0004465)
1.1	48.9	GO:0003777	microtubule motor activity(GO:0003777)
1.1	57.4	GO:0034987	immunoglobulin receptor binding(GO:0034987)
1.1	3.2	GO:0046848	hydroxyapatite binding(GO:0046848)
1.1	210.3	GO:0050839	cell adhesion molecule binding(GO:0050839)
1.0	20.9	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
1.0	5.2	GO:0047066	phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
1.0	10.3	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.0	5.1	GO:0031543	peptidyl-proline dioxygenase activity(GO:0031543)
1.0	8.2	GO:0030882	lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
1.0	9.2	GO:0008199	ferric iron binding(GO:0008199)
1.0	13.2	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
1.0	210.8	GO:0003924	GTPase activity(GO:0003924)
1.0	3.9	GO:0099580	ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
1.0	31.9	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
1.0	11.4	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.9	36.7	GO:0009055	electron carrier activity(GO:0009055)
0.9	20.4	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.9	8.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.9	13.6	GO:0048406	nerve growth factor binding(GO:0048406)
0.9	2.6	GO:0015254	glycerol channel activity(GO:0015254)
0.9	7.0	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.8	3.3	GO:0004177	aminopeptidase activity(GO:0004177)
0.8	29.7	GO:0042805	actinin binding(GO:0042805)
0.8	1.6	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.8	2.4	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.8	17.3	GO:0044390	ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.8	1.6	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.8	2.3	GO:0003988	acetyl-CoA C-acetyltransferase activity(GO:0003985) acetyl-CoA C-acyltransferase activity(GO:0003988)
0.7	6.7	GO:0016875	aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.7	10.3	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.7	4.4	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.7	11.6	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.7	93.4	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.7	4.2	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.7	9.3	GO:0004383	guanylate cyclase activity(GO:0004383)
0.7	3.9	GO:0004046	aminoacylase activity(GO:0004046)
0.6	4.4	GO:0033691	sialic acid binding(GO:0033691)
0.6	3.1	GO:0004140	dephospho-CoA kinase activity(GO:0004140)
0.6	1.9	GO:0070402	NADPH binding(GO:0070402)
0.6	4.3	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.6	40.5	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.6	1.8	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.6	2.3	GO:0032190	acrosin binding(GO:0032190)
0.6	1.7	GO:0016524	latrotoxin receptor activity(GO:0016524)
0.6	7.9	GO:0016881	acid-amino acid ligase activity(GO:0016881)
0.6	2.2	GO:0004911	interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.5	3.3	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.5	2.7	GO:0004017	adenylate kinase activity(GO:0004017)
0.5	23.9	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.5	2.6	GO:0071723	lipopeptide binding(GO:0071723)
0.5	6.6	GO:0016868	intramolecular transferase activity, phosphotransferases(GO:0016868)
0.5	1.5	GO:0019863	IgE binding(GO:0019863)
0.5	5.4	GO:0070410	co-SMAD binding(GO:0070410)
0.5	9.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.5	24.5	GO:0032947	protein complex scaffold(GO:0032947)
0.5	1.9	GO:0016495	C-X3-C chemokine receptor activity(GO:0016495)
0.5	3.7	GO:0015232	heme transporter activity(GO:0015232)
0.5	2.3	GO:0004666	prostaglandin-endoperoxide synthase activity(GO:0004666)
0.5	1.4	GO:0031208	POZ domain binding(GO:0031208)
0.5	4.1	GO:0042043	neurexin family protein binding(GO:0042043)
0.4	6.6	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.4	1.3	GO:0070492	oligosaccharide binding(GO:0070492)
0.4	2.1	GO:0047696	beta-adrenergic receptor kinase activity(GO:0047696)
0.4	2.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.4	102.0	GO:0008236	serine-type peptidase activity(GO:0008236)
0.4	1.6	GO:0070051	fibrinogen binding(GO:0070051)
0.4	2.8	GO:0046870	cadmium ion binding(GO:0046870)
0.4	18.0	GO:0016765	transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.4	3.1	GO:0043014	alpha-tubulin binding(GO:0043014)
0.4	6.9	GO:0051287	NAD binding(GO:0051287)
0.4	14.2	GO:0001190	transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.4	1.9	GO:0016778	diphosphotransferase activity(GO:0016778)
0.4	1.1	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.4	3.3	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.4	2.1	GO:0048495	Roundabout binding(GO:0048495)
0.3	1.0	GO:0050509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.3	126.2	GO:0003712	transcription cofactor activity(GO:0003712)
0.3	4.8	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.3	2.6	GO:0008046	axon guidance receptor activity(GO:0008046)
0.3	7.2	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3	1.0	GO:0005011	macrophage colony-stimulating factor receptor activity(GO:0005011)
0.3	1.6	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.3	1.6	GO:0042979	ornithine decarboxylase inhibitor activity(GO:0008073) ornithine decarboxylase regulator activity(GO:0042979)
0.3	2.8	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.3	0.9	GO:0019150	D-ribulokinase activity(GO:0019150)
0.3	0.9	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.3	1.2	GO:0008823	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3	0.9	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.3	3.9	GO:0017081	chloride channel regulator activity(GO:0017081)
0.3	4.9	GO:0048487	beta-tubulin binding(GO:0048487)
0.3	1.0	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.2	1.0	GO:0004331	fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.2	0.7	GO:0046577	long-chain-alcohol oxidase activity(GO:0046577)
0.2	0.9	GO:0004522	ribonuclease A activity(GO:0004522)
0.2	0.7	GO:0004047	aminomethyltransferase activity(GO:0004047)
0.2	0.9	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.2	1.2	GO:0097016	L27 domain binding(GO:0097016)
0.2	0.7	GO:0003858	3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.2	5.5	GO:0019956	chemokine binding(GO:0019956)
0.2	2.4	GO:0030280	structural constituent of epidermis(GO:0030280)
0.2	1.5	GO:0044213	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2	0.9	GO:0023024	MHC class I protein complex binding(GO:0023024)
0.2	1.1	GO:0047894	flavonol 3-sulfotransferase activity(GO:0047894)
0.2	10.3	GO:0016811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.2	1.0	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1	0.6	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.1	2.1	GO:0022829	wide pore channel activity(GO:0022829)
0.1	1.6	GO:0001608	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1	2.6	GO:0051539	4 iron, 4 sulfur cluster binding(GO:0051539)
0.1	8.8	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.1	0.7	GO:0042731	PH domain binding(GO:0042731)
0.1	0.8	GO:0008432	JUN kinase binding(GO:0008432)
0.1	2.2	GO:0002039	p53 binding(GO:0002039)
0.1	0.4	GO:0016882	cyclo-ligase activity(GO:0016882)
0.1	0.5	GO:0005353	fructose transmembrane transporter activity(GO:0005353)
0.1	0.5	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.1	0.5	GO:0030021	extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.1	0.2	GO:0001224	RNA polymerase II transcription cofactor binding(GO:0001224)
0.0	1.6	GO:0015485	cholesterol binding(GO:0015485)
0.0	0.9	GO:0004033	aldo-keto reductase (NADP) activity(GO:0004033)
0.0	0.3	GO:0015174	basic amino acid transmembrane transporter activity(GO:0015174)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183) C4-dicarboxylate transmembrane transporter activity(GO:0015556)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
12.8	654.9	PID BARD1 PATHWAY	BARD1 signaling events
11.8	317.8	PID ARF 3PATHWAY	Arf1 pathway
11.7	46.8	PID TRAIL PATHWAY	TRAIL signaling pathway
11.3	124.8	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
10.2	325.6	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
10.1	888.7	PID RAC1 PATHWAY	RAC1 signaling pathway
9.8	137.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
9.5	492.3	PID ATR PATHWAY	ATR signaling pathway
9.3	167.4	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
8.4	377.6	PID AURORA A PATHWAY	Aurora A signaling
7.9	276.2	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
7.7	199.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
7.7	581.4	PID ILK PATHWAY	Integrin-linked kinase signaling
7.2	171.8	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
7.1	335.1	PID ALK1 PATHWAY	ALK1 signaling events
7.0	267.1	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
6.9	510.2	PID CD8 TCR PATHWAY	TCR signaling in naïve CD8+ T cells
6.8	857.1	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation
6.6	26.5	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
6.3	177.5	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
6.3	177.1	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
6.2	271.6	PID FOXM1 PATHWAY	FOXM1 transcription factor network
5.2	352.7	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
5.2	207.0	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
5.1	199.5	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
5.1	442.8	PID E2F PATHWAY	E2F transcription factor network
4.8	100.8	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
4.3	99.4	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
4.1	150.4	PID PLK1 PATHWAY	PLK1 signaling events
3.8	174.5	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
3.8	135.2	PID HIF2PATHWAY	HIF-2-alpha transcription factor network
3.6	39.7	PID FANCONI PATHWAY	Fanconi anemia pathway
3.6	132.2	PID AURORA B PATHWAY	Aurora B signaling
3.5	14.1	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
3.2	6.3	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
3.1	137.1	PID P53 REGULATION PATHWAY	p53 pathway
3.1	120.2	PID IL6 7 PATHWAY	IL6-mediated signaling events
3.0	119.5	PID TNF PATHWAY	TNF receptor signaling pathway
2.9	37.3	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
2.8	50.5	PID IL3 PATHWAY	IL3-mediated signaling events
2.8	22.3	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
2.7	16.3	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
2.7	13.3	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
2.6	25.6	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
2.5	66.1	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
2.5	55.6	SIG BCR SIGNALING PATHWAY	Members of the BCR signaling pathway
2.5	358.8	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
2.5	66.6	ST P38 MAPK PATHWAY	p38 MAPK Pathway
2.4	16.8	ST JNK MAPK PATHWAY	JNK MAPK Pathway
2.3	22.7	PID FOXO PATHWAY	FoxO family signaling
2.1	10.7	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
2.1	46.6	PID INSULIN PATHWAY	Insulin Pathway
2.1	8.2	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling
2.0	23.4	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
1.9	101.2	PID TELOMERASE PATHWAY	Regulation of Telomerase
1.9	24.3	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
1.8	48.8	PID IFNG PATHWAY	IFN-gamma pathway
1.8	14.5	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
1.8	5.4	PID ERBB4 PATHWAY	ErbB4 signaling events
1.7	36.3	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
1.7	43.0	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
1.7	20.6	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
1.6	122.6	PID RHOA REG PATHWAY	Regulation of RhoA activity
1.6	62.7	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
1.6	16.1	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
1.6	12.8	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
1.6	31.7	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
1.5	44.1	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
1.5	56.1	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
1.5	55.6	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
1.5	16.3	PID CD40 PATHWAY	CD40/CD40L signaling
1.4	44.7	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
1.4	116.9	PID CMYB PATHWAY	C-MYB transcription factor network
1.3	10.8	PID WNT SIGNALING PATHWAY	Wnt signaling network
1.2	8.3	PID GMCSF PATHWAY	GMCSF-mediated signaling events
1.2	34.2	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
1.2	28.8	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
1.1	15.3	PID IL2 1PATHWAY	IL2-mediated signaling events
1.1	47.0	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
1.1	23.5	PID S1P S1P1 PATHWAY	S1P1 pathway
1.1	10.7	PID BCR 5PATHWAY	BCR signaling pathway
1.0	4.1	PID MYC PATHWAY	C-MYC pathway
1.0	54.4	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.9	41.2	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.9	6.1	PID CXCR3 PATHWAY	CXCR3-mediated signaling events
0.9	28.1	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
0.8	18.4	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.8	47.1	PID P73PATHWAY	p73 transcription factor network
0.8	45.2	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.8	7.0	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.8	3.9	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.7	29.5	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.7	48.3	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.7	29.9	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.7	13.9	PID RHOA PATHWAY	RhoA signaling pathway
0.7	3.6	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.7	12.0	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.7	11.1	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.7	15.5	PID IL4 2PATHWAY	IL4-mediated signaling events
0.7	11.1	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.6	12.1	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.6	23.4	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.6	30.7	PID SYNDECAN 1 PATHWAY	Syndecan-1-mediated signaling events
0.6	13.1	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.6	6.7	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.5	6.9	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.5	17.7	PID RB 1PATHWAY	Regulation of retinoblastoma protein
0.5	1.9	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.5	20.1	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.4	12.5	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.4	5.4	ST G ALPHA S PATHWAY	G alpha s Pathway
0.4	2.4	PID IL27 PATHWAY	IL27-mediated signaling events
0.3	6.5	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.2	4.2	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	2.2	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.1	3.2	PID CD8 TCR DOWNSTREAM PATHWAY	Downstream signaling in naïve CD8+ T cells
0.1	1.7	PID ATM PATHWAY	ATM pathway
0.1	1.0	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.5	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
34.4	2373.8	REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6	Genes involved in CDK-mediated phosphorylation and removal of Cdc6
32.5	487.1	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
30.3	333.0	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
26.7	1972.9	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
26.5	291.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
24.9	572.1	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
24.8	446.8	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
21.0	2731.5	REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE	Genes involved in SRP-dependent cotranslational protein targeting to membrane
21.0	21.0	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
20.0	379.6	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
19.4	116.6	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
19.3	405.5	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
19.2	38.3	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
18.0	844.0	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
17.5	525.0	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
17.4	538.8	REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1	Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
15.9	539.5	REACTOME ENOS ACTIVATION AND REGULATION	Genes involved in eNOS activation and regulation
15.3	230.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
14.7	1691.7	REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA	Genes involved in Processing of Capped Intron-Containing Pre-mRNA
14.4	346.3	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
14.0	42.0	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
13.8	220.8	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
13.6	189.9	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
13.3	437.5	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
13.0	143.3	REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX	Genes involved in Formation of RNA Pol II elongation complex
12.9	129.1	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)
12.9	218.8	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
12.7	228.8	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
11.9	381.6	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
11.9	190.2	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
11.8	212.3	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
11.6	46.6	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
11.2	168.0	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
11.1	255.1	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
10.9	98.0	REACTOME CYTOSOLIC TRNA AMINOACYLATION	Genes involved in Cytosolic tRNA aminoacylation
10.4	585.1	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
10.4	145.5	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
9.9	98.7	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
9.7	448.2	REACTOME TRANSLATION	Genes involved in Translation
9.6	57.4	REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION	Genes involved in Influenza Viral RNA Transcription and Replication
9.5	391.4	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
9.4	159.5	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
9.4	786.8	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
9.2	220.5	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
9.0	261.5	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
8.3	141.4	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
8.1	113.8	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
8.1	113.2	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
8.0	208.6	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
8.0	424.2	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
8.0	31.9	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
7.9	151.0	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
7.9	424.1	REACTOME G1 PHASE	Genes involved in G1 Phase
7.6	182.0	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
7.6	211.7	REACTOME KINESINS	Genes involved in Kinesins
7.4	282.9	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
7.4	273.9	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
7.3	29.1	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
6.9	13.7	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
6.9	123.6	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
6.7	73.9	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
6.7	214.9	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
6.4	216.2	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
6.2	174.3	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
6.1	79.3	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
6.1	121.6	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
5.9	356.0	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
5.9	892.1	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
5.9	47.0	REACTOME PURINE CATABOLISM	Genes involved in Purine catabolism
5.8	190.8	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
5.8	5.8	REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC	Genes involved in Formation of tubulin folding intermediates by CCT/TriC
5.7	215.0	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
5.6	128.6	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
5.6	16.7	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
5.5	164.6	REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS	Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
5.4	81.6	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
5.4	108.3	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
5.4	59.1	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
5.4	101.8	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
5.1	205.1	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
5.1	46.1	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
5.1	76.6	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
5.0	25.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
4.9	97.5	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
4.8	101.7	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
4.8	67.1	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
4.7	145.2	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
4.4	13.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
4.2	71.3	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
4.2	50.2	REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY	Genes involved in Adenylate cyclase inhibitory pathway
4.2	29.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
4.1	49.4	REACTOME MRNA PROCESSING	Genes involved in mRNA Processing
4.0	84.9	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
4.0	24.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
4.0	71.6	REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS	Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
3.8	172.7	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
3.8	60.9	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
3.8	76.0	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
3.7	85.8	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
3.6	51.0	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
3.6	119.0	REACTOME G2 M CHECKPOINTS	Genes involved in G2/M Checkpoints
3.5	21.0	REACTOME SIGNALING BY WNT	Genes involved in Signaling by Wnt
3.5	97.2	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
3.5	45.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
3.5	107.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
3.5	34.5	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
3.5	10.4	REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX	Genes involved in CDT1 association with the CDC6:ORC:origin complex
3.4	135.0	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
3.2	25.6	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
3.2	25.6	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
3.2	113.5	REACTOME SIGNAL TRANSDUCTION BY L1	Genes involved in Signal transduction by L1
3.1	367.8	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
3.1	15.3	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
3.0	3.0	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
2.9	240.1	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
2.9	11.4	REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS	Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
2.8	85.5	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
2.7	16.4	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
2.7	51.4	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
2.7	10.7	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
2.7	21.3	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
2.5	22.8	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
2.5	49.7	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
2.5	9.8	REACTOME SIGNALING BY NOTCH2	Genes involved in Signaling by NOTCH2
2.5	44.1	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
2.4	22.0	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
2.4	47.1	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
2.3	112.4	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
2.3	2.3	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
2.2	186.6	REACTOME APOPTOTIC EXECUTION PHASE	Genes involved in Apoptotic execution phase
2.0	28.6	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
2.0	6.0	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
2.0	29.8	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
1.9	42.4	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
1.9	94.4	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
1.9	36.4	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
1.9	13.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
1.8	99.9	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
1.8	78.0	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
1.7	85.0	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
1.5	1.5	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
1.4	144.9	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
1.4	8.2	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
1.4	37.9	REACTOME ACTIVATION OF KAINATE RECEPTORS UPON GLUTAMATE BINDING	Genes involved in Activation of Kainate Receptors upon glutamate binding
1.3	28.8	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
1.2	17.8	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
1.1	18.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
1.1	13.5	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
1.1	4.4	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
1.0	7.1	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
1.0	31.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
1.0	25.4	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
1.0	25.3	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
1.0	22.0	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.9	13.2	REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN	Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.9	3.6	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.8	18.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.8	33.7	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.8	34.1	REACTOME TRANS GOLGI NETWORK VESICLE BUDDING	Genes involved in trans-Golgi Network Vesicle Budding
0.8	0.8	REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION	Genes involved in Glucagon signaling in metabolic regulation
0.7	20.9	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.7	48.8	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.7	14.0	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.7	7.9	REACTOME ASPARAGINE N LINKED GLYCOSYLATION	Genes involved in Asparagine N-linked glycosylation
0.7	15.7	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.6	25.0	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.6	17.1	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.6	3.6	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.6	15.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.4	45.2	REACTOME SIGNALING BY RHO GTPASES	Genes involved in Signaling by Rho GTPases
0.4	2.5	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.4	4.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.4	1.9	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.3	6.0	REACTOME CD28 DEPENDENT PI3K AKT SIGNALING	Genes involved in CD28 dependent PI3K/Akt signaling
0.3	45.4	REACTOME METABOLISM OF CARBOHYDRATES	Genes involved in Metabolism of carbohydrates
0.2	3.0	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.2	4.0	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.2	1.7	REACTOME PLATELET CALCIUM HOMEOSTASIS	Genes involved in Platelet calcium homeostasis
0.2	1.5	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.1	0.3	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1	9.1	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.1	1.5	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	2.0	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.1	1.1	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.1	1.6	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	1.1	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle

Results for ELF2_GABPA_ELF5

Z-value: 12.17

Motif logo

Transcription factors associated with ELF2_GABPA_ELF5

Activity-expression correlation:

Activity profile of ELF2_GABPA_ELF5 motif

Sorted Z-values of ELF2_GABPA_ELF5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ELF2_GABPA_ELF5

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: