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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for EN1_ESX1_GBX1

Z-value: 6.94

Motif logo

Transcription factors associated with EN1_ESX1_GBX1

Gene Symbol Gene ID Gene Info
ENSG00000163064.7 EN1
ENSG00000123576.5 ESX1
ENSG00000164900.5 GBX1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GBX1hg38_v1_chr7_-_151167692_1511676970.421.4e-10Click!
EN1hg38_v1_chr2_-_118847638_1188476540.111.0e-01Click!

Activity profile of EN1_ESX1_GBX1 motif

Sorted Z-values of EN1_ESX1_GBX1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EN1_ESX1_GBX1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_-_111923722 41.48 ENST00000527950.5
crystallin alpha B
chr3_+_111998739 35.40 ENST00000393917.6
ENST00000273368.8
transgelin 3
chr3_+_111999189 34.94 ENST00000455401.6
transgelin 3
chr3_+_111999326 34.14 ENST00000494932.1
transgelin 3
chr19_+_44905785 31.07 ENST00000446996.5
ENST00000252486.9
ENST00000434152.5
apolipoprotein E
chr3_+_111998915 31.05 ENST00000478951.6
transgelin 3
chrX_-_13817027 30.79 ENST00000493677.5
ENST00000355135.6
ENST00000316715.9
glycoprotein M6B
chr11_-_117876719 30.10 ENST00000529335.6
ENST00000260282.8
FXYD domain containing ion transport regulator 6
chr11_-_117877463 29.61 ENST00000527717.5
FXYD domain containing ion transport regulator 6
chr12_-_6124662 29.00 ENST00000261405.10
von Willebrand factor
chr11_-_117876892 28.79 ENST00000539526.5
FXYD domain containing ion transport regulator 6
chr12_-_16606795 25.02 ENST00000447609.5
LIM domain only 3
chr4_+_112860981 24.56 ENST00000671704.1
ankyrin 2
chr4_-_46909235 24.47 ENST00000505102.1
ENST00000355591.8
cytochrome c oxidase subunit 7B2
chr4_-_46909206 23.94 ENST00000396533.5
cytochrome c oxidase subunit 7B2
chr4_+_112860912 23.78 ENST00000671951.1
ankyrin 2
chr4_+_112861053 23.01 ENST00000672221.1
ankyrin 2
chr16_+_58249910 22.10 ENST00000219299.8
ENST00000443128.6
ENST00000616795.1
coiled-coil domain containing 113
chr8_+_104223320 20.65 ENST00000339750.3
regulating synaptic membrane exocytosis 2
chr2_-_223602284 18.96 ENST00000421386.1
ENST00000305409.3
ENST00000433889.1
secretogranin II
chr5_-_42811884 18.82 ENST00000514985.6
ENST00000511224.5
ENST00000507920.5
ENST00000510965.1
selenoprotein P
chr5_+_67004618 18.49 ENST00000261569.11
ENST00000436277.5
microtubule associated serine/threonine kinase family member 4
chr10_-_49762335 18.09 ENST00000419399.4
ENST00000432695.2
oxoglutarate dehydrogenase L
chr4_+_7043315 17.94 ENST00000310074.8
ENST00000512388.1
transcriptional adaptor 2B
chr10_-_49762276 17.49 ENST00000374103.9
oxoglutarate dehydrogenase L
chr12_+_26195313 17.40 ENST00000422622.3
sarcospan
chr14_+_92323154 17.27 ENST00000532405.6
ENST00000676001.1
ENST00000531433.5
solute carrier family 24 member 4
chr1_-_117929557 17.20 ENST00000369442.3
ENST00000369443.10
ganglioside induced differentiation associated protein 2
chr10_-_91633057 17.08 ENST00000238994.6
protein phosphatase 1 regulatory subunit 3C
chr14_+_103715767 15.89 ENST00000311141.7
zinc finger FYVE-type containing 21
chr14_+_103715724 15.67 ENST00000216602.10
zinc finger FYVE-type containing 21
chr7_-_137343752 15.44 ENST00000393083.2
pleiotrophin
chr11_-_129192198 15.43 ENST00000310343.13
Rho GTPase activating protein 32
chr8_+_104223344 15.14 ENST00000523362.5
regulating synaptic membrane exocytosis 2
chr1_-_92486916 14.56 ENST00000294702.6
growth factor independent 1 transcriptional repressor
chr14_+_99481395 14.42 ENST00000389879.9
ENST00000557441.5
ENST00000555049.5
ENST00000555842.1
cyclin K
chr12_+_6904733 14.09 ENST00000007969.12
ENST00000622489.4
ENST00000443597.7
ENST00000323702.9
leucine rich repeat containing 23
chr12_+_80716906 14.03 ENST00000228644.4
myogenic factor 5
chr4_-_8871817 13.99 ENST00000400677.5
H6 family homeobox 1
chr7_-_83649097 13.76 ENST00000643230.2
semaphorin 3E
chr14_-_103715433 13.64 ENST00000554913.5
ENST00000555055.6
ENST00000554974.5
ENST00000553361.5
ENST00000555964.5
ENST00000556682.5
ENST00000553332.5
ENST00000352127.11
X-ray repair cross complementing 3
chr6_-_166627244 13.64 ENST00000265678.9
ribosomal protein S6 kinase A2
chr11_-_129024157 13.32 ENST00000392657.7
Rho GTPase activating protein 32
chr16_-_29899532 13.26 ENST00000308713.9
ENST00000617533.5
seizure related 6 homolog like 2
chr8_-_33567118 13.12 ENST00000256257.2
ring finger protein 122
chr4_-_56681588 13.08 ENST00000554144.5
ENST00000381260.7
HOP homeobox
chr22_-_18936142 12.91 ENST00000438924.5
ENST00000457083.1
ENST00000357068.11
ENST00000420436.5
ENST00000334029.6
ENST00000610940.4
proline dehydrogenase 1
chr5_+_141484997 12.75 ENST00000617094.1
ENST00000306593.2
ENST00000610539.1
ENST00000618371.4
protocadherin gamma subfamily C, 4
chr4_-_56681288 12.44 ENST00000556376.6
ENST00000420433.6
HOP homeobox
chr1_-_151790475 12.41 ENST00000368825.7
ENST00000368823.5
ENST00000368824.8
ENST00000458431.6
ENST00000368827.10
ENST00000440583.6
tudor and KH domain containing
chr19_+_4007714 12.03 ENST00000262971.3
protein inhibitor of activated STAT 4
chr1_+_43650118 11.26 ENST00000372396.4
lysine demethylase 4A
chr12_-_114403898 11.10 ENST00000526441.1
T-box transcription factor 5
chr10_+_84194527 10.85 ENST00000623527.4
cadherin related family member 1
chr4_-_145180496 10.47 ENST00000447906.8
OTU deubiquitinase 4
chr6_-_39725387 10.46 ENST00000287152.12
kinesin family member 6
chr8_+_49911396 10.42 ENST00000642720.2
syntrophin gamma 1
chr11_-_101129806 10.01 ENST00000325455.10
ENST00000617858.4
ENST00000619228.2
progesterone receptor
chr8_+_9555900 9.84 ENST00000310430.11
ENST00000520408.5
ENST00000522110.1
tankyrase
chr15_+_62561361 9.76 ENST00000561311.5
talin 2
chr8_-_18887018 9.43 ENST00000523619.5
pleckstrin and Sec7 domain containing 3
chr15_+_58410543 9.36 ENST00000356113.10
ENST00000414170.7
lipase C, hepatic type
chr1_+_27935022 9.33 ENST00000411604.5
ENST00000373888.8
sphingomyelin phosphodiesterase acid like 3B
chr18_+_34976928 9.04 ENST00000591734.5
ENST00000413393.5
ENST00000589180.5
ENST00000587359.5
microtubule associated protein RP/EB family member 2
chr3_+_115623502 8.89 ENST00000305124.11
ENST00000393780.3
growth associated protein 43
chr12_+_6904962 8.81 ENST00000415834.5
ENST00000436789.5
leucine rich repeat containing 23
chr11_-_129192291 8.73 ENST00000682385.1
Rho GTPase activating protein 32
chr7_-_73624492 8.63 ENST00000414749.6
ENST00000429400.6
ENST00000434326.5
ENST00000313375.8
ENST00000354613.5
ENST00000453275.1
MLX interacting protein like
chr14_+_99684283 8.58 ENST00000261835.8
cytochrome P450 family 46 subfamily A member 1
chr3_-_138329839 8.48 ENST00000333911.9
ENST00000383180.6
NME/NM23 family member 9
chr6_-_110179995 8.47 ENST00000392586.5
ENST00000419252.1
ENST00000359451.6
ENST00000392588.5
WASP family member 1
chr7_+_2519763 8.40 ENST00000222725.10
ENST00000359574.7
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr18_-_14132423 8.37 ENST00000589498.5
ENST00000590202.3
zinc finger protein 519
chr12_-_91153149 8.14 ENST00000550758.1
decorin
chr2_-_101308681 8.10 ENST00000295317.4
ring finger protein 149
chr4_+_70721953 8.05 ENST00000381006.8
ENST00000226328.8
RUN and FYVE domain containing 3
chr14_+_32329256 7.94 ENST00000280979.9
A-kinase anchoring protein 6
chr6_+_72216442 7.93 ENST00000425662.6
ENST00000453976.6
regulating synaptic membrane exocytosis 1
chr12_+_119668109 7.91 ENST00000229328.10
ENST00000630317.1
protein kinase AMP-activated non-catalytic subunit beta 1
chr6_+_39792298 7.86 ENST00000633794.1
ENST00000274867.9
dishevelled associated activator of morphogenesis 2
chr16_-_29899245 7.76 ENST00000537485.5
seizure related 6 homolog like 2
chr17_-_66229380 7.72 ENST00000205948.11
apolipoprotein H
chr14_-_74084393 7.71 ENST00000350259.8
ENST00000553458.6
aldehyde dehydrogenase 6 family member A1
chr6_+_72216745 7.70 ENST00000517827.5
regulating synaptic membrane exocytosis 1
chr1_+_202348687 7.59 ENST00000608999.6
ENST00000391959.5
ENST00000480184.5
protein phosphatase 1 regulatory subunit 12B
chr8_-_42843201 7.41 ENST00000529779.1
ENST00000345117.2
ENST00000254250.7
THAP domain containing 1
chr3_-_161105399 7.31 ENST00000652593.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr4_-_108762964 7.30 ENST00000512646.5
ENST00000411864.6
ENST00000296486.8
ENST00000510706.5
ethanolamine-phosphate phospho-lyase
chr12_+_26195543 7.17 ENST00000242729.7
sarcospan
chr6_+_26087281 7.15 ENST00000353147.9
ENST00000397022.7
ENST00000352392.8
ENST00000349999.8
ENST00000317896.11
ENST00000470149.5
ENST00000336625.12
ENST00000461397.5
ENST00000488199.5
homeostatic iron regulator
chr2_-_207167220 7.14 ENST00000421199.5
ENST00000457962.5
Kruppel like factor 7
chr17_-_10026265 7.11 ENST00000437099.6
ENST00000396115.6
growth arrest specific 7
chr9_-_76692181 7.09 ENST00000376717.6
ENST00000223609.10
prune homolog 2 with BCH domain
chr19_+_54137740 7.07 ENST00000644245.1
ENST00000646002.1
ENST00000221232.11
ENST00000440571.6
ENST00000617930.2
CCR4-NOT transcription complex subunit 3
chr14_+_24114627 7.06 ENST00000559115.5
ENST00000558215.5
ENST00000557810.5
ENST00000561375.5
ENST00000446197.8
ENST00000559796.5
ENST00000560713.5
ENST00000560901.5
ENST00000559382.5
ENST00000561001.5
DDB1 and CUL4 associated factor 11
chr9_-_5304713 7.05 ENST00000381627.4
relaxin 2
chr8_-_22232020 6.92 ENST00000454243.7
ENST00000321613.7
phytanoyl-CoA 2-hydroxylase interacting protein
chr1_-_145095528 6.89 ENST00000612199.4
ENST00000641863.1
SLIT-ROBO Rho GTPase activating protein 2B
chr2_+_200440649 6.88 ENST00000366118.2
spermatogenesis associated serine rich 2 like
chr3_-_161105070 6.74 ENST00000651430.1
ENST00000650695.1
ENST00000651689.1
ENST00000651916.1
ENST00000488170.5
ENST00000652377.1
ENST00000652669.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr9_-_5339874 6.74 ENST00000223862.2
relaxin 1
chr22_+_41381923 6.69 ENST00000266304.9
TEF transcription factor, PAR bZIP family member
chr4_+_94974984 6.64 ENST00000672698.1
bone morphogenetic protein receptor type 1B
chr11_+_24496988 6.59 ENST00000336930.11
leucine zipper protein 2
chr6_-_62286161 6.59 ENST00000281156.5
KH RNA binding domain containing, signal transduction associated 2
chr6_+_131250375 6.45 ENST00000474850.2
A-kinase anchoring protein 7
chr19_+_49513353 6.42 ENST00000596975.5
Fc fragment of IgG receptor and transporter
chr10_+_94683722 6.28 ENST00000285979.11
cytochrome P450 family 2 subfamily C member 18
chr5_-_160852200 6.25 ENST00000327245.10
ATPase phospholipid transporting 10B (putative)
chr6_+_31815532 6.20 ENST00000375651.7
ENST00000608703.1
heat shock protein family A (Hsp70) member 1A
chr14_-_24114913 6.20 ENST00000561028.6
ENST00000558280.1
neural retina leucine zipper
chr4_-_88284553 6.16 ENST00000608933.6
ENST00000295908.11
protein phosphatase, Mg2+/Mn2+ dependent 1K
chr1_+_121184964 6.11 ENST00000367123.8
SLIT-ROBO Rho GTPase activating protein 2C
chr4_+_105710809 6.07 ENST00000360505.9
ENST00000510865.5
ENST00000509336.5
glutathione S-transferase C-terminal domain containing
chr2_+_68734861 6.03 ENST00000467265.5
Rho GTPase activating protein 25
chr3_+_167735704 6.01 ENST00000446050.7
ENST00000295777.9
ENST00000472747.2
serpin family I member 1
chr14_+_74084947 5.91 ENST00000674221.1
ENST00000554938.2
lin-52 DREAM MuvB core complex component
chr11_-_101129706 5.90 ENST00000534013.5
progesterone receptor
chr1_+_196819731 5.82 ENST00000320493.10
ENST00000367424.4
complement factor H related 1
chr6_+_72212802 5.80 ENST00000401910.7
regulating synaptic membrane exocytosis 1
chr17_+_44187190 5.80 ENST00000319511.6
transmembrane and ubiquitin like domain containing 2
chr5_+_77086682 5.74 ENST00000643365.1
ENST00000645183.1
ENST00000645374.1
ENST00000647364.1
ENST00000643848.1
ENST00000643603.1
ENST00000645459.1
ENST00000643269.1
ENST00000503969.6
ENST00000646262.1
ZBED3 antisense RNA 1
phosphodiesterase 8B
chr8_-_86743626 5.67 ENST00000320005.6
cyclic nucleotide gated channel subunit beta 3
chr5_-_24644968 5.65 ENST00000264463.8
cadherin 10
chr1_-_27672178 5.63 ENST00000339145.8
ENST00000361157.11
ENST00000362020.4
ENST00000679644.1
interferon alpha inducible protein 6
chr2_+_170178136 5.63 ENST00000409044.7
ENST00000408978.9
myosin IIIB
chr10_-_97445850 5.61 ENST00000477692.6
ENST00000485122.6
ENST00000370886.9
ENST00000370885.8
ENST00000370902.8
ENST00000370884.5
exosome component 1
chr7_+_99828010 5.54 ENST00000631161.2
ENST00000354829.7
ENST00000342499.8
ENST00000417625.5
ENST00000415413.5
ENST00000444905.5
ENST00000222382.5
ENST00000312017.9
cytochrome P450 family 3 subfamily A member 43
chr2_+_112542413 5.54 ENST00000417433.6
ENST00000263331.10
RNA polymerase I subunit B
chr14_-_52069039 5.52 ENST00000216286.10
nidogen 2
chr5_-_20575850 5.52 ENST00000507958.5
cadherin 18
chr9_-_92878018 5.51 ENST00000332591.6
ENST00000375495.8
ENST00000395505.6
ENST00000395506.7
zinc finger protein 484
chr14_+_32329341 5.51 ENST00000557354.5
ENST00000557102.1
ENST00000557272.1
A-kinase anchoring protein 6
chr11_-_108222594 5.51 ENST00000278612.9
nuclear protein, coactivator of histone transcription
chr19_+_49513154 5.50 ENST00000426395.7
ENST00000600273.5
ENST00000599988.5
Fc fragment of IgG receptor and transporter
chr7_+_70596078 5.45 ENST00000644506.1
activator of transcription and developmental regulator AUTS2
chr10_-_28282086 5.44 ENST00000375719.7
ENST00000375732.5
membrane palmitoylated protein 7
chr2_-_208124514 5.42 ENST00000264376.5
crystallin gamma D
chr14_-_52069228 5.41 ENST00000617139.4
nidogen 2
chr8_+_49911604 5.40 ENST00000642164.1
ENST00000644093.1
ENST00000643999.1
ENST00000647073.1
ENST00000646880.1
syntrophin gamma 1
chr9_-_114505437 5.38 ENST00000374057.3
ENST00000362057.4
ENST00000673697.1
whirlin
chr10_-_97687191 5.29 ENST00000370626.4
arginine vasopressin induced 1
chrX_+_10158448 5.27 ENST00000380829.5
ENST00000421085.7
ENST00000674669.1
ENST00000454850.1
chloride voltage-gated channel 4
chr2_-_53859929 5.19 ENST00000394705.3
ENST00000406625.6
G protein-coupled receptor 75
ankyrin repeat and SOCS box containing 3
chr12_-_11395556 5.18 ENST00000565533.1
ENST00000389362.6
ENST00000546254.3
proline rich protein BstNI subfamily 2
proline rich protein BstNI subfamily 1
chr11_-_117876612 5.15 ENST00000584230.1
ENST00000526014.6
ENST00000584394.5
ENST00000614497.5
ENST00000532984.1
FXYD domain containing ion transport regulator 6
FXYD6-FXYD2 readthrough
chr10_+_7703340 5.14 ENST00000429820.5
ENST00000379587.4
inter-alpha-trypsin inhibitor heavy chain 2
chr17_-_75667088 5.14 ENST00000578201.5
ENST00000423245.6
ENST00000317905.10
RecQ like helicase 5
chr6_-_100464912 5.12 ENST00000369208.8
SIM bHLH transcription factor 1
chr6_+_72212887 5.06 ENST00000523963.5
regulating synaptic membrane exocytosis 1
chr11_+_94973640 5.04 ENST00000335080.6
ENST00000536741.1
lysine demethylase 4D
chr14_-_81533800 5.01 ENST00000555824.5
ENST00000557372.1
ENST00000336735.9
SEL1L adaptor subunit of ERAD E3 ubiquitin ligase
chr13_-_36214521 5.00 ENST00000379881.8
spermatogenesis and oogenesis specific basic helix-loop-helix 2
chr22_-_33572227 4.97 ENST00000674780.1
LARGE xylosyl- and glucuronyltransferase 1
chr17_+_42458844 4.95 ENST00000393829.6
ENST00000537728.5
ENST00000343619.9
ENST00000264649.10
ENST00000585525.5
ENST00000544137.5
ENST00000589727.5
ENST00000587824.5
ATPase H+ transporting V0 subunit a1
chr7_+_154305105 4.87 ENST00000332007.7
dipeptidyl peptidase like 6
chr2_-_74392025 4.85 ENST00000440727.1
ENST00000409240.5
dynactin subunit 1
chr1_+_209704836 4.85 ENST00000367027.5
hydroxysteroid 11-beta dehydrogenase 1
chrM_+_12329 4.83 ENST00000361567.2
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5
chr1_+_145927105 4.80 ENST00000437797.5
ENST00000601726.3
ENST00000599626.5
ENST00000599147.5
ENST00000595494.5
ENST00000595518.5
ENST00000597144.5
ENST00000599469.5
ENST00000598354.5
ENST00000598103.5
ENST00000600340.5
ENST00000630257.2
ENST00000625258.1
LIX1L antisense RNA 1
novel protein, lncRNA-POLR3GL readthrough
chr19_-_19192122 4.80 ENST00000444486.7
ENST00000514819.7
ENST00000585679.1
ENST00000462790.8
myocyte enhancer factor 2B
BORCS8-MEF2B readthrough
BLOC-1 related complex subunit 8
chr6_-_49713564 4.79 ENST00000616725.4
ENST00000618917.4
cysteine rich secretory protein 2
chr17_-_1628808 4.75 ENST00000301335.10
solute carrier family 43 member 2
chr9_+_96450115 4.73 ENST00000375249.5
ENST00000375251.7
hyaluronan binding protein 4
chr12_+_53380141 4.72 ENST00000551969.5
ENST00000327443.9
Sp1 transcription factor
chr17_-_75667165 4.67 ENST00000584999.1
ENST00000420326.6
ENST00000340830.9
RecQ like helicase 5
chrX_+_53082358 4.67 ENST00000375442.8
ENST00000579390.1
TSPY like 2
chr3_-_161105224 4.67 ENST00000651254.1
ENST00000651178.1
ENST00000476999.6
ENST00000652596.1
ENST00000651305.1
ENST00000652111.1
ENST00000651292.1
ENST00000651282.1
ENST00000651380.1
ENST00000494173.7
ENST00000484127.5
ENST00000650733.1
ENST00000494818.6
ENST00000492353.5
ENST00000652143.1
ENST00000473142.5
ENST00000651147.1
ENST00000468268.5
ENST00000460353.2
ENST00000651953.1
ENST00000651972.1
ENST00000652730.1
ENST00000651460.1
ENST00000652059.1
ENST00000651509.1
ENST00000651801.1
ENST00000651686.1
ENST00000320474.10
ENST00000392781.7
ENST00000392779.6
ENST00000651791.1
ENST00000651117.1
ENST00000652032.1
beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr14_-_100569780 4.59 ENST00000355173.7
brain enriched guanylate kinase associated
chr5_+_161850597 4.55 ENST00000634335.1
ENST00000635880.1
gamma-aminobutyric acid type A receptor subunit alpha1
chr12_+_48105466 4.50 ENST00000549003.5
ENST00000550924.6
phosphofructokinase, muscle
chr6_-_31139063 4.47 ENST00000259845.5
psoriasis susceptibility 1 candidate 2
chrX_+_30235894 4.46 ENST00000620842.1
MAGE family member B3
chr14_+_74348440 4.46 ENST00000256362.5
vertebrae development associated
chrX_-_140505058 4.43 ENST00000370536.5
SRY-box transcription factor 3
chr16_+_86566821 4.38 ENST00000649859.1
forkhead box C2
chr1_+_160190567 4.37 ENST00000368078.8
calsequestrin 1
chr7_+_100586304 4.34 ENST00000241071.11
F-box protein 24
chr15_+_99105071 4.32 ENST00000328642.11
ENST00000594047.2
ENST00000336292.11
synemin
chr1_-_37554277 4.25 ENST00000296215.8
Smad nuclear interacting protein 1
chr7_+_149838365 4.24 ENST00000460379.1
ENST00000223210.5
zinc finger protein 862
chr2_+_80305105 4.22 ENST00000541047.5
catenin alpha 2
chr3_+_4680617 4.21 ENST00000648212.1
inositol 1,4,5-trisphosphate receptor type 1
chr15_-_77420135 4.20 ENST00000560626.6
pseudopodium enriched atypical kinase 1
chr4_+_73409340 4.19 ENST00000511370.1
albumin
chr15_-_77420087 4.18 ENST00000564328.5
ENST00000682557.1
ENST00000558305.5
pseudopodium enriched atypical kinase 1
chr14_-_74923234 4.16 ENST00000556776.1
ENST00000557413.6
ENST00000555647.5
ribosomal protein S6 kinase like 1
chr19_-_41364119 4.13 ENST00000243578.8
B9 domain containing 2
chr16_-_55833085 4.06 ENST00000360526.8
carboxylesterase 1
chr17_+_44187210 4.05 ENST00000589785.1
ENST00000592825.1
ENST00000589184.5
transmembrane and ubiquitin like domain containing 2
chr3_-_112641128 4.04 ENST00000206423.8
coiled-coil domain containing 80
chr5_+_140841183 4.02 ENST00000378123.4
ENST00000531613.2
protocadherin alpha 8
chr18_+_13218769 4.02 ENST00000677055.1
ENST00000399848.7
low density lipoprotein receptor class A domain containing 4
chr10_+_70404129 4.00 ENST00000373218.5
eukaryotic translation initiation factor 4E binding protein 2
chr8_-_85341659 4.00 ENST00000522389.5
carbonic anhydrase 1
chr12_-_10130241 3.99 ENST00000353231.9
ENST00000525605.1
C-type lectin domain containing 7A
chr12_-_113335030 3.98 ENST00000552014.5
ENST00000680972.1
ENST00000548186.5
ENST00000202831.7
ENST00000549181.5
solute carrier family 8 member B1
chr12_+_56080126 3.93 ENST00000411731.6
erb-b2 receptor tyrosine kinase 3
chr16_+_7303245 3.88 ENST00000674626.1
RNA binding fox-1 homolog 1
chr6_-_49713521 3.86 ENST00000339139.5
cysteine rich secretory protein 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
9.3 46.5 GO:1901628 positive regulation of postsynaptic membrane organization(GO:1901628)
7.1 71.3 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
4.9 14.6 GO:0070105 positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
4.8 14.4 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
4.5 13.6 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
4.3 12.9 GO:0010133 proline catabolic process to glutamate(GO:0010133)
4.0 35.8 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
4.0 11.9 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
3.7 11.1 GO:0003218 cardiac left ventricle formation(GO:0003218)
3.6 25.0 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
3.3 9.8 GO:1904908 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) protein auto-ADP-ribosylation(GO:0070213) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of telomeric DNA binding(GO:1904742) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
3.2 15.9 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
2.6 7.7 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
2.6 30.8 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
2.5 9.8 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
2.4 7.1 GO:1903989 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
2.2 13.4 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
2.1 6.4 GO:1990451 cellular stress response to acidic pH(GO:1990451)
2.1 8.4 GO:0051037 regulation of transcription involved in meiotic cell cycle(GO:0051037)
2.0 34.8 GO:0007021 tubulin complex assembly(GO:0007021)
2.0 16.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
1.8 5.4 GO:0098582 innate vocalization behavior(GO:0098582)
1.8 14.3 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
1.8 12.4 GO:0034587 piRNA metabolic process(GO:0034587)
1.8 26.5 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
1.7 12.0 GO:1902231 positive regulation of keratinocyte apoptotic process(GO:1902174) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
1.7 8.4 GO:0007386 compartment pattern specification(GO:0007386)
1.6 4.8 GO:1990418 response to insulin-like growth factor stimulus(GO:1990418)
1.6 4.7 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
1.6 32.6 GO:0001829 trophectodermal cell differentiation(GO:0001829)
1.5 6.1 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
1.5 40.0 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
1.5 4.4 GO:0070409 carbamoyl phosphate metabolic process(GO:0070408) carbamoyl phosphate biosynthetic process(GO:0070409) cellular response to oleic acid(GO:0071400) response to ammonia(GO:1903717) cellular response to ammonia(GO:1903718)
1.5 4.4 GO:0072144 positive regulation of vascular wound healing(GO:0035470) mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144)
1.4 4.2 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
1.4 19.0 GO:0048245 eosinophil chemotaxis(GO:0048245)
1.3 3.9 GO:0015847 putrescine transport(GO:0015847)
1.3 2.5 GO:2000296 regulation of hydrogen peroxide catabolic process(GO:2000295) negative regulation of hydrogen peroxide catabolic process(GO:2000296)
1.2 6.2 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
1.2 8.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.2 6.9 GO:0016554 cytidine to uridine editing(GO:0016554)
1.1 5.6 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
1.1 2.2 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
1.1 4.3 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
1.1 13.0 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
1.1 7.6 GO:0048241 epinephrine transport(GO:0048241)
1.1 1.1 GO:0086092 regulation of the force of heart contraction by cardiac conduction(GO:0086092)
1.0 2.1 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
1.0 11.1 GO:0006685 sphingomyelin catabolic process(GO:0006685)
1.0 7.9 GO:0035878 nail development(GO:0035878)
1.0 8.9 GO:0016198 axon choice point recognition(GO:0016198)
1.0 1.0 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
1.0 83.4 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.9 6.6 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.9 2.8 GO:0071934 thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934)
0.9 1.9 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.9 12.7 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.9 5.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.9 4.5 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.9 20.5 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.9 3.5 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.9 4.4 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.9 5.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.9 17.2 GO:0097186 amelogenesis(GO:0097186)
0.9 8.6 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.9 2.6 GO:1903892 negative regulation of ATF6-mediated unfolded protein response(GO:1903892)
0.8 2.5 GO:0002326 B cell lineage commitment(GO:0002326)
0.8 5.7 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.8 5.5 GO:0007000 nucleolus organization(GO:0007000)
0.8 15.6 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.7 3.7 GO:0070778 L-aspartate transport(GO:0070778) L-aspartate transmembrane transport(GO:0089712)
0.7 2.1 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025) mast cell proliferation(GO:0070662)
0.7 3.4 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.7 2.7 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.6 1.9 GO:0021538 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.6 1.9 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.6 1.9 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.6 8.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.6 2.5 GO:0090290 hormone-mediated apoptotic signaling pathway(GO:0008628) positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.6 1.9 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.6 1.2 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.6 9.8 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.6 1.8 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.6 2.9 GO:0010746 regulation of plasma membrane long-chain fatty acid transport(GO:0010746) negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.6 16.4 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.6 54.0 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.6 4.0 GO:0086036 regulation of cardiac muscle cell membrane potential(GO:0086036)
0.6 1.7 GO:0061074 neuroblast differentiation(GO:0014016) regulation of neural retina development(GO:0061074) regulation of retina development in camera-type eye(GO:1902866)
0.6 3.3 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.6 1.7 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.6 1.7 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241) sarcomerogenesis(GO:0048769)
0.6 2.2 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.5 0.5 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.5 1.6 GO:0015808 L-alanine transport(GO:0015808)
0.5 4.3 GO:0001887 selenium compound metabolic process(GO:0001887)
0.5 4.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.5 3.1 GO:0050955 thermoception(GO:0050955)
0.5 7.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.5 1.5 GO:0015860 purine nucleoside transmembrane transport(GO:0015860)
0.5 28.5 GO:0006458 'de novo' protein folding(GO:0006458)
0.5 14.9 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.5 5.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.5 17.9 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.5 1.9 GO:0051697 protein delipidation(GO:0051697)
0.5 1.4 GO:0072366 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948) regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.5 4.2 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.4 5.8 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.4 1.8 GO:0051140 positive regulation of activation of Janus kinase activity(GO:0010536) regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.4 2.2 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.4 2.2 GO:0030070 insulin processing(GO:0030070)
0.4 3.4 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.4 8.5 GO:0006228 UTP biosynthetic process(GO:0006228)
0.4 9.7 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.4 3.8 GO:0070475 rRNA base methylation(GO:0070475)
0.4 2.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.4 2.5 GO:0071395 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.4 2.8 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.4 2.3 GO:0006710 androgen catabolic process(GO:0006710)
0.4 7.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.4 4.2 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.4 5.0 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.4 13.4 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.4 2.2 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.4 4.1 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.4 2.8 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.3 4.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.3 1.7 GO:0010513 positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.3 2.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.3 4.9 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.3 4.5 GO:0032196 transposition(GO:0032196)
0.3 0.9 GO:0097272 ammonia homeostasis(GO:0097272)
0.3 3.4 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.3 0.9 GO:0035425 autocrine signaling(GO:0035425)
0.3 1.7 GO:0035063 nuclear speck organization(GO:0035063)
0.3 2.9 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.3 2.0 GO:0060087 relaxation of vascular smooth muscle(GO:0060087)
0.3 1.1 GO:0021815 cell motility involved in cerebral cortex radial glia guided migration(GO:0021814) modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration(GO:0021815)
0.3 1.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.3 2.4 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.3 0.8 GO:0070375 ERK5 cascade(GO:0070375)
0.3 2.1 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.3 5.4 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.3 1.3 GO:0021559 trigeminal nerve development(GO:0021559)
0.2 6.0 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.2 2.4 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.2 4.6 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.2 0.7 GO:0055020 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm development(GO:0048389) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) pattern specification involved in mesonephros development(GO:0061227) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in kidney development(GO:0072098) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter urothelium development(GO:0072190) ureter epithelial cell differentiation(GO:0072192) ureter morphogenesis(GO:0072197) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007) negative regulation of cell proliferation involved in heart morphogenesis(GO:2000137)
0.2 13.8 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.2 6.3 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.2 4.8 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.2 0.7 GO:0018874 benzoate metabolic process(GO:0018874) butyrate metabolic process(GO:0019605)
0.2 7.4 GO:0071711 basement membrane organization(GO:0071711)
0.2 8.1 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.2 4.8 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.2 0.2 GO:2000538 regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.2 30.1 GO:0006757 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.2 1.5 GO:0009048 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.2 6.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.2 4.7 GO:1902475 L-alpha-amino acid transmembrane transport(GO:1902475)
0.2 31.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 3.1 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.2 2.0 GO:0006069 ethanol oxidation(GO:0006069)
0.2 1.7 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.2 4.4 GO:0007530 sex determination(GO:0007530)
0.2 3.1 GO:0006706 steroid catabolic process(GO:0006706)
0.2 0.4 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320)
0.2 4.6 GO:0071420 cellular response to histamine(GO:0071420)
0.2 2.0 GO:0009642 response to light intensity(GO:0009642)
0.2 1.6 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.2 2.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.2 0.9 GO:0061051 positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.2 2.5 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.2 0.5 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.2 1.7 GO:0007638 mechanosensory behavior(GO:0007638)
0.2 0.9 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842)
0.1 0.4 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 1.0 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 2.1 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.1 7.9 GO:0007368 determination of left/right symmetry(GO:0007368)
0.1 2.5 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 6.8 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.4 GO:0043589 skin morphogenesis(GO:0043589)
0.1 0.6 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 1.6 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 2.2 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 2.5 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1 5.4 GO:0070306 lens fiber cell differentiation(GO:0070306)
0.1 1.4 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 3.5 GO:0015813 L-glutamate transport(GO:0015813)
0.1 2.8 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 1.3 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.1 2.1 GO:0048730 epidermis morphogenesis(GO:0048730)
0.1 2.8 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 4.0 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.4 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.1 2.7 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.1 14.3 GO:0032526 response to retinoic acid(GO:0032526)
0.1 2.9 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.1 1.8 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090) maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.1 27.2 GO:0060271 cilium morphogenesis(GO:0060271)
0.1 3.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 1.4 GO:0034391 smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391)
0.1 0.4 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.1 0.8 GO:0030450 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.1 3.2 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.1 1.1 GO:2000169 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.1 0.4 GO:1902725 regulation of skeletal muscle tissue growth(GO:0048631) negative regulation of satellite cell differentiation(GO:1902725)
0.1 2.8 GO:0007616 long-term memory(GO:0007616)
0.1 7.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 0.3 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.1 0.7 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 6.4 GO:0035690 cellular response to drug(GO:0035690)
0.1 2.1 GO:0002792 negative regulation of peptide secretion(GO:0002792) negative regulation of insulin secretion(GO:0046676) negative regulation of peptide hormone secretion(GO:0090278)
0.1 0.7 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1 7.6 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.1 5.7 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 69.7 GO:0007417 central nervous system development(GO:0007417)
0.1 3.8 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.1 2.3 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.1 1.0 GO:0032411 positive regulation of transporter activity(GO:0032411)
0.1 1.3 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.5 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.1 3.4 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.1 27.0 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.1 1.1 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 1.0 GO:0070327 thyroid hormone transport(GO:0070327)
0.1 2.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 3.8 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 7.3 GO:0048024 regulation of mRNA splicing, via spliceosome(GO:0048024)
0.1 4.6 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 1.8 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.1 0.2 GO:0043017 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.1 4.0 GO:0031214 biomineral tissue development(GO:0031214)
0.1 4.7 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 0.7 GO:0061436 regulation of water loss via skin(GO:0033561) establishment of skin barrier(GO:0061436)
0.1 2.4 GO:0075733 intracellular transport of virus(GO:0075733)
0.1 1.4 GO:0030199 collagen fibril organization(GO:0030199)
0.1 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.1 5.1 GO:0097194 execution phase of apoptosis(GO:0097194)
0.1 2.0 GO:0050918 positive chemotaxis(GO:0050918)
0.1 5.6 GO:0006937 regulation of muscle contraction(GO:0006937)
0.1 2.4 GO:0042246 tissue regeneration(GO:0042246)
0.1 1.3 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.6 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 2.4 GO:0016574 histone ubiquitination(GO:0016574)
0.0 2.0 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.6 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 6.3 GO:0007411 axon guidance(GO:0007411)
0.0 0.4 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 1.6 GO:0072164 ureteric bud development(GO:0001657) mesonephros development(GO:0001823) mesonephric epithelium development(GO:0072163) mesonephric tubule development(GO:0072164)
0.0 1.0 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.6 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 2.0 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.6 GO:0042761 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 2.4 GO:0032418 lysosome localization(GO:0032418)
0.0 0.5 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 2.7 GO:0030183 B cell differentiation(GO:0030183)
0.0 1.3 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0 1.0 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 3.9 GO:0002576 platelet degranulation(GO:0002576)
0.0 0.1 GO:0042635 positive regulation of hair cycle(GO:0042635) positive regulation of hair follicle development(GO:0051798)
0.0 1.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 4.3 GO:0071805 cellular potassium ion transport(GO:0071804) potassium ion transmembrane transport(GO:0071805)
0.0 0.5 GO:0014823 response to activity(GO:0014823)
0.0 1.5 GO:2000117 negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.0 0.7 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.0 0.3 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:0030728 ovulation(GO:0030728)
0.0 1.8 GO:0007548 sex differentiation(GO:0007548)
0.0 1.2 GO:0008277 regulation of G-protein coupled receptor protein signaling pathway(GO:0008277)
0.0 2.1 GO:0006936 muscle contraction(GO:0006936)
0.0 1.0 GO:0050796 regulation of insulin secretion(GO:0050796)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
7.8 31.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
5.1 35.6 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
3.6 14.4 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
3.1 12.4 GO:0071546 pi-body(GO:0071546)
3.0 48.4 GO:0045277 respiratory chain complex IV(GO:0045277)
2.6 41.5 GO:0097512 cardiac myofibril(GO:0097512)
2.2 13.5 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
2.0 5.9 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
1.7 13.4 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
1.6 6.2 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
1.5 8.9 GO:0032584 growth cone membrane(GO:0032584)
1.4 17.3 GO:0016013 syntrophin complex(GO:0016013)
1.4 67.8 GO:0031430 M band(GO:0031430)
1.3 26.5 GO:0031089 platelet dense granule lumen(GO:0031089)
1.3 20.4 GO:0030914 STAGA complex(GO:0030914)
1.2 6.0 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
1.2 7.1 GO:1990357 terminal web(GO:1990357)
1.1 62.3 GO:0048786 presynaptic active zone(GO:0048786)
1.0 22.7 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.9 19.0 GO:0031045 dense core granule(GO:0031045)
0.9 4.4 GO:0014802 terminal cisterna(GO:0014802)
0.8 12.5 GO:0000242 pericentriolar material(GO:0000242)
0.8 14.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.8 5.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.8 10.0 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.7 4.5 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.7 16.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.7 6.8 GO:0005614 interstitial matrix(GO:0005614)
0.7 25.4 GO:0034451 centriolar satellite(GO:0034451)
0.7 8.5 GO:0031209 SCAR complex(GO:0031209)
0.6 3.2 GO:0036398 TCR signalosome(GO:0036398)
0.6 8.9 GO:0005869 dynactin complex(GO:0005869)
0.6 2.5 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.6 4.3 GO:0043034 costamere(GO:0043034)
0.6 7.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.6 1.7 GO:0097224 sperm connecting piece(GO:0097224)
0.6 3.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.6 6.6 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.5 6.4 GO:0071438 invadopodium membrane(GO:0071438)
0.5 3.6 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.5 2.5 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.5 4.9 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.5 2.4 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.5 129.9 GO:0043209 myelin sheath(GO:0043209)
0.5 2.8 GO:0071797 LUBAC complex(GO:0071797)
0.4 3.1 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.4 3.1 GO:0060091 kinocilium(GO:0060091)
0.4 4.0 GO:0030061 mitochondrial crista(GO:0030061)
0.4 5.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.4 3.4 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.4 3.3 GO:0005593 FACIT collagen trimer(GO:0005593)
0.4 4.5 GO:0008385 IkappaB kinase complex(GO:0008385)
0.4 7.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.4 14.7 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.4 6.9 GO:0036038 MKS complex(GO:0036038)
0.4 4.2 GO:0005955 calcineurin complex(GO:0005955)
0.4 9.0 GO:0035371 microtubule plus-end(GO:0035371)
0.3 5.5 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.3 1.4 GO:0001940 male pronucleus(GO:0001940)
0.3 4.6 GO:0001673 male germ cell nucleus(GO:0001673)
0.3 7.2 GO:0031672 A band(GO:0031672)
0.3 29.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.3 2.0 GO:1990130 Iml1 complex(GO:1990130)
0.3 5.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.3 2.4 GO:0000813 ESCRT I complex(GO:0000813)
0.3 2.0 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.2 5.1 GO:0097342 ripoptosome(GO:0097342)
0.2 2.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 2.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 1.1 GO:0044327 dendritic spine head(GO:0044327)
0.2 1.5 GO:0044530 supraspliceosomal complex(GO:0044530)
0.2 12.1 GO:0031594 neuromuscular junction(GO:0031594)
0.2 7.1 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.2 62.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.2 1.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 5.4 GO:0032420 stereocilium(GO:0032420)
0.2 3.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.2 0.9 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.1 6.2 GO:0016235 aggresome(GO:0016235)
0.1 8.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 4.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 10.6 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 1.8 GO:0031906 late endosome lumen(GO:0031906)
0.1 15.2 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 3.4 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 18.3 GO:0072562 blood microparticle(GO:0072562)
0.1 13.8 GO:0043204 perikaryon(GO:0043204)
0.1 2.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 3.0 GO:0030057 desmosome(GO:0030057)
0.1 4.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 4.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 5.9 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 1.5 GO:0001533 cornified envelope(GO:0001533)
0.1 0.9 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 2.5 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 6.0 GO:0030017 sarcomere(GO:0030017)
0.1 6.6 GO:0031225 anchored component of membrane(GO:0031225)
0.1 2.5 GO:0031904 endosome lumen(GO:0031904)
0.1 1.9 GO:0034707 chloride channel complex(GO:0034707)
0.1 0.9 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 2.2 GO:0097060 synaptic membrane(GO:0097060)
0.1 9.3 GO:0034399 nuclear periphery(GO:0034399)
0.0 0.9 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.4 GO:0097452 GAIT complex(GO:0097452)
0.0 80.1 GO:0005887 integral component of plasma membrane(GO:0005887)
0.0 1.3 GO:0098858 actin-based cell projection(GO:0098858)
0.0 0.8 GO:0005902 microvillus(GO:0005902)
0.0 2.6 GO:0043235 receptor complex(GO:0043235)
0.0 9.1 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 2.1 GO:0005884 actin filament(GO:0005884)
0.0 13.8 GO:0005925 focal adhesion(GO:0005925)
0.0 2.3 GO:0008021 synaptic vesicle(GO:0008021)
0.0 7.6 GO:0005765 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 5.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 1.9 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 1.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 16.3 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 2.6 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.4 GO:0055029 DNA-directed RNA polymerase complex(GO:0000428) RNA polymerase complex(GO:0030880) nuclear DNA-directed RNA polymerase complex(GO:0055029)
0.0 0.4 GO:0043195 terminal bouton(GO:0043195)
0.0 0.5 GO:0005811 lipid particle(GO:0005811)
0.0 0.3 GO:0005905 clathrin-coated pit(GO:0005905)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
7.8 31.1 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
7.1 35.6 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
5.3 31.6 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
3.9 15.4 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
3.7 18.7 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
3.0 11.9 GO:0019770 IgG receptor activity(GO:0019770)
2.9 17.3 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
2.4 7.3 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
2.1 6.4 GO:0030171 voltage-gated proton channel activity(GO:0030171)
2.1 8.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
2.0 12.0 GO:0061665 SUMO ligase activity(GO:0061665)
1.9 13.6 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.9 7.7 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
1.9 7.6 GO:0005277 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
1.7 50.1 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.6 49.1 GO:0005212 structural constituent of eye lens(GO:0005212)
1.6 9.8 GO:0009378 four-way junction helicase activity(GO:0009378)
1.6 4.8 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
1.6 18.8 GO:0008430 selenium binding(GO:0008430)
1.5 4.6 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
1.4 1.4 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
1.3 3.9 GO:0015203 polyamine transmembrane transporter activity(GO:0015203) putrescine transmembrane transporter activity(GO:0015489)
1.3 85.7 GO:0017080 sodium channel regulator activity(GO:0017080)
1.3 5.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.2 11.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
1.1 70.5 GO:0030507 spectrin binding(GO:0030507)
1.1 3.4 GO:0017129 triglyceride binding(GO:0017129)
1.1 3.3 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
1.1 31.0 GO:0019865 immunoglobulin binding(GO:0019865)
1.1 4.4 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
1.0 8.9 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.9 5.7 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.9 2.8 GO:0015234 thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403)
0.9 3.8 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.9 2.8 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.9 4.5 GO:0004803 transposase activity(GO:0004803)
0.9 2.7 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.9 16.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.8 5.1 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.8 5.0 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.8 2.5 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.8 4.1 GO:0047374 sterol esterase activity(GO:0004771) methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.8 12.0 GO:0030215 semaphorin receptor binding(GO:0030215)
0.8 3.1 GO:0004773 steryl-sulfatase activity(GO:0004773)
0.7 13.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.7 3.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.7 7.9 GO:0039706 co-receptor binding(GO:0039706)
0.7 2.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.7 4.2 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.7 4.7 GO:0000182 rDNA binding(GO:0000182)
0.7 14.4 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.6 2.5 GO:0005148 prolactin receptor binding(GO:0005148)
0.6 13.3 GO:0070330 aromatase activity(GO:0070330)
0.6 144.7 GO:0051015 actin filament binding(GO:0051015)
0.6 5.9 GO:0004064 arylesterase activity(GO:0004064)
0.6 7.9 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.6 6.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.6 4.5 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.6 6.6 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.5 8.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.5 4.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.5 4.6 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.5 4.0 GO:0030345 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.5 5.5 GO:0038132 neuregulin binding(GO:0038132)
0.5 16.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.5 1.9 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.5 6.4 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.5 17.4 GO:0042056 chemoattractant activity(GO:0042056)
0.5 10.5 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.5 10.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.4 1.3 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.4 12.9 GO:0071949 FAD binding(GO:0071949)
0.4 4.4 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.4 4.3 GO:0019215 intermediate filament binding(GO:0019215)
0.4 2.1 GO:0031711 tripeptidyl-peptidase activity(GO:0008240) peptidyl-dipeptidase activity(GO:0008241) bradykinin receptor binding(GO:0031711) metallodipeptidase activity(GO:0070573)
0.4 1.6 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.4 2.4 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.4 3.2 GO:0030275 LRR domain binding(GO:0030275)
0.4 2.0 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.4 7.7 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.4 1.5 GO:0005415 nucleoside:sodium symporter activity(GO:0005415)
0.4 3.2 GO:0004969 histamine receptor activity(GO:0004969)
0.4 2.5 GO:0030492 hemoglobin binding(GO:0030492)
0.3 5.5 GO:0001054 RNA polymerase I activity(GO:0001054)
0.3 1.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.3 4.7 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.3 4.0 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.3 3.9 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.3 3.4 GO:0046625 sphingolipid binding(GO:0046625)
0.3 53.9 GO:0044325 ion channel binding(GO:0044325)
0.3 4.0 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.3 2.4 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.3 21.0 GO:0048365 Rac GTPase binding(GO:0048365)
0.3 0.9 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.3 1.8 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.3 8.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.3 0.9 GO:0050815 phosphoserine binding(GO:0050815)
0.3 1.7 GO:0032027 myosin light chain binding(GO:0032027)
0.3 25.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.3 5.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.3 2.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.3 1.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.3 6.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.3 5.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.3 17.7 GO:0070888 E-box binding(GO:0070888)
0.3 20.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.3 9.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.3 2.0 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.2 1.7 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 6.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 1.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.2 6.9 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.2 1.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 20.4 GO:0051117 ATPase binding(GO:0051117)
0.2 1.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 24.3 GO:0003774 motor activity(GO:0003774)
0.2 4.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.2 14.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.2 3.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.2 0.6 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.2 3.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 0.5 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.2 6.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.2 0.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 4.7 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 0.7 GO:0097108 hedgehog family protein binding(GO:0097108)
0.2 1.0 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.2 6.6 GO:0008143 poly(A) binding(GO:0008143)
0.2 2.2 GO:0015643 toxic substance binding(GO:0015643)
0.2 0.8 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.2 3.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.2 1.8 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.2 4.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.2 1.0 GO:1990226 histone methyltransferase binding(GO:1990226)
0.2 4.0 GO:0001968 fibronectin binding(GO:0001968)
0.2 0.9 GO:0042301 phosphate ion binding(GO:0042301)
0.2 3.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.2 0.8 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.1 1.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 4.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.1 4.4 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 3.5 GO:0002162 dystroglycan binding(GO:0002162)
0.1 2.5 GO:0048018 receptor agonist activity(GO:0048018)
0.1 5.6 GO:0004532 exoribonuclease activity(GO:0004532)
0.1 7.3 GO:0070412 R-SMAD binding(GO:0070412)
0.1 43.9 GO:0005096 GTPase activator activity(GO:0005096)
0.1 4.8 GO:0004177 aminopeptidase activity(GO:0004177)
0.1 36.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 4.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 4.9 GO:0008536 nuclear localization sequence binding(GO:0008139) Ran GTPase binding(GO:0008536)
0.1 11.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 2.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 2.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 3.2 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 2.8 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 3.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.4 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.1 0.6 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.7 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 1.7 GO:0005109 frizzled binding(GO:0005109)
0.1 0.5 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.1 1.8 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 1.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 2.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 16.7 GO:0061630 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.1 0.7 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.1 2.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.9 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.6 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 0.8 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 1.0 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 3.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 6.5 GO:0005179 hormone activity(GO:0005179)
0.0 3.4 GO:0002039 p53 binding(GO:0002039)
0.0 10.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 4.2 GO:0005518 collagen binding(GO:0005518)
0.0 0.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 3.9 GO:0042826 histone deacetylase binding(GO:0042826)
0.0 3.0 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 3.0 GO:0032947 protein complex scaffold(GO:0032947)
0.0 3.4 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.4 GO:0004527 exonuclease activity(GO:0004527)
0.0 5.7 GO:0008017 microtubule binding(GO:0008017)
0.0 1.3 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.8 GO:0017091 AU-rich element binding(GO:0017091)
0.0 2.0 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 1.9 GO:0005254 chloride channel activity(GO:0005254)
0.0 2.6 GO:0008201 heparin binding(GO:0008201)
0.0 6.7 GO:0003779 actin binding(GO:0003779)
0.0 0.5 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.0 11.5 GO:0005509 calcium ion binding(GO:0005509)
0.0 0.1 GO:0048185 activin binding(GO:0048185)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 1.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.9 GO:0004540 ribonuclease activity(GO:0004540)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 15.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.5 14.0 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.3 12.0 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.3 16.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.3 12.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.3 6.4 PID CONE PATHWAY Visual signal transduction: Cones
0.3 15.3 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.3 5.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2 2.9 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.2 4.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 13.1 PID NCADHERIN PATHWAY N-cadherin signaling events
0.2 8.9 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.2 4.2 SIG CHEMOTAXIS Genes related to chemotaxis
0.2 2.8 PID LPA4 PATHWAY LPA4-mediated signaling events
0.2 3.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.2 13.2 PID LKB1 PATHWAY LKB1 signaling events
0.2 5.5 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 5.6 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 7.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 8.2 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 6.4 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 3.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 8.8 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 24.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 3.4 PID MYC PATHWAY C-MYC pathway
0.1 2.9 PID INSULIN PATHWAY Insulin Pathway
0.1 4.0 PID BMP PATHWAY BMP receptor signaling
0.1 7.9 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.1 2.0 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 1.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 9.2 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 1.0 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 2.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 1.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.1 2.1 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.0 PID ATM PATHWAY ATM pathway
0.1 2.4 PID P53 REGULATION PATHWAY p53 pathway
0.0 3.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.8 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.7 PID IL23 PATHWAY IL23-mediated signaling events
0.0 2.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 1.8 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 1.0 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 3.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.4 PID P73PATHWAY p73 transcription factor network
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.3 PID EPHB FWD PATHWAY EPHB forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 29.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
1.7 36.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
1.2 26.5 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.8 11.0 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.7 8.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.6 13.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.5 9.7 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.5 13.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.5 5.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.5 11.1 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.4 7.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.4 4.5 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.4 16.3 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.4 5.9 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.3 2.4 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.3 8.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.3 10.7 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.3 5.5 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.3 3.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.3 5.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.3 7.7 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.3 2.9 REACTOME OPSINS Genes involved in Opsins
0.2 3.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.2 14.6 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 17.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.2 2.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.2 3.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 5.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.2 2.4 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.2 15.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 7.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 2.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.2 5.5 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.2 5.8 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.2 3.1 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.2 3.0 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.2 2.9 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 1.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 5.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 5.7 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 2.8 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 6.4 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 2.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.1 1.7 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.1 11.1 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 3.1 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.1 2.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 3.6 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.1 1.0 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 5.2 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 3.1 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.2 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 8.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 3.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 2.2 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.1 2.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 4.2 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.1 11.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 1.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 0.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 3.6 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.8 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 1.2 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 1.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 3.1 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.1 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 1.9 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.0 0.4 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.2 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.9 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 1.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.9 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 1.5 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.0 0.4 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.9 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism