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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for EOMES

Z-value: 6.80

Motif logo

Transcription factors associated with EOMES

Gene Symbol Gene ID Gene Info
ENSG00000163508.13 EOMES

Activity profile of EOMES motif

Sorted Z-values of EOMES motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EOMES

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr15_-_90994494 29.07 ENST00000559811.1
ENST00000442656.6
ENST00000557905.5
ENST00000394249.8
protein regulator of cytokinesis 1
chr14_-_55191534 26.99 ENST00000395425.6
ENST00000247191.7
DLG associated protein 5
chr8_-_63038788 23.88 ENST00000518113.2
ENST00000260118.7
ENST00000677482.1
gamma-glutamyl hydrolase
chr10_-_56361235 21.76 ENST00000373944.8
ENST00000361148.6
ENST00000395405.5
ZW10 interacting kinetochore protein
chr7_-_96709780 18.48 ENST00000623693.3
ENST00000623498.3
ENST00000488005.5
ENST00000413065.5
SEM1 26S proteasome complex subunit
chr14_+_54397021 17.45 ENST00000541304.5
cyclin dependent kinase inhibitor 3
chr7_-_100100716 15.44 ENST00000354230.7
ENST00000425308.5
minichromosome maintenance complex component 7
chr3_-_167734465 14.27 ENST00000487947.6
programmed cell death 10
chr2_+_201071984 13.51 ENST00000237889.9
ENST00000433898.5
ENST00000684175.1
ENST00000682325.1
ENST00000454214.1
ENST00000684420.1
NADH:ubiquinone oxidoreductase subunit B3
chr11_-_57335854 13.50 ENST00000529002.2
ENST00000278412.7
structure specific recognition protein 1
chr1_+_193060034 12.65 ENST00000367446.7
ENST00000367443.5
ENST00000367444.7
ENST00000367445.7
Ro60, Y RNA binding protein
chr2_-_69437588 12.38 ENST00000394305.5
NFU1 iron-sulfur cluster scaffold
chr1_-_167937037 11.81 ENST00000271373.9
mitochondrial pyruvate carrier 2
chr8_-_123396412 11.59 ENST00000287394.10
ATPase family AAA domain containing 2
chr22_+_40346508 11.33 ENST00000636714.1
ENST00000216194.11
ENST00000623978.3
ENST00000636265.1
ENST00000680378.1
adenylosuccinate lyase
chr7_+_87876472 11.18 ENST00000265728.6
DBF4 zinc finger
chr20_-_59042748 11.12 ENST00000355937.9
ENST00000371033.9
PRELI domain containing 3B
chr3_+_160399630 11.10 ENST00000465903.5
ENST00000485645.5
ENST00000472991.5
ENST00000467468.5
ENST00000469762.5
ENST00000357388.8
ENST00000489573.5
ENST00000462787.5
ENST00000490207.5
ENST00000485867.5
structural maintenance of chromosomes 4
chr14_+_96797304 10.93 ENST00000553683.2
ENST00000680538.1
ENST00000681195.1
ENST00000679727.1
ENST00000680509.1
ENST00000557222.6
ENST00000680683.1
ENST00000680335.1
ENST00000216639.8
ENST00000679736.1
ENST00000681176.1
ENST00000557352.2
ENST00000679903.1
ENST00000681419.1
ENST00000680849.1
ENST00000681493.1
ENST00000679770.1
ENST00000681355.1
ENST00000681344.1
VRK serine/threonine kinase 1
chr11_+_32583792 10.66 ENST00000531120.6
ENST00000524896.5
ENST00000323213.9
eukaryotic translation initiation factor 3 subunit M
chr7_+_5045821 10.59 ENST00000353796.7
ENST00000396912.2
ENST00000396904.2
RB associated KRAB zinc finger
RBAK-RBAKDN readthrough
chr2_-_233854506 10.47 ENST00000411486.7
Holliday junction recognition protein
chr12_+_32679200 10.37 ENST00000452533.6
ENST00000414834.6
dynamin 1 like
chr2_-_69437417 10.26 ENST00000450796.6
ENST00000484177.5
ENST00000410022.7
ENST00000303698.7
NFU1 iron-sulfur cluster scaffold
chr1_-_165768835 10.26 ENST00000481278.5
transmembrane and coiled-coil domains 1
chr3_-_123992046 10.08 ENST00000467907.5
ENST00000459660.5
ENST00000495093.1
ENST00000460743.5
ENST00000405845.7
ENST00000484329.1
ENST00000479867.1
ENST00000496145.5
rhophilin associated tail protein 1
chrX_+_21940693 9.75 ENST00000404933.7
ENST00000379404.5
spermine synthase
chr8_+_42391895 9.67 ENST00000521158.5
voltage dependent anion channel 3
chr3_-_167734510 9.60 ENST00000475915.6
ENST00000462725.6
ENST00000461494.5
programmed cell death 10
chr5_-_80654552 9.46 ENST00000511032.5
ENST00000504396.1
ENST00000505337.5
dihydrofolate reductase
chr11_+_34052210 9.44 ENST00000532820.5
cell cycle associated protein 1
chr2_-_233854566 9.43 ENST00000432087.5
ENST00000441687.5
ENST00000414924.5
Holliday junction recognition protein
chr8_-_108248700 9.39 ENST00000220849.10
ENST00000678937.1
ENST00000678901.1
ENST00000678243.1
ENST00000677674.1
ENST00000521297.2
ENST00000677272.1
ENST00000522352.6
ENST00000678042.1
ENST00000519627.2
ENST00000521440.6
ENST00000678773.1
ENST00000676698.1
ENST00000518345.2
ENST00000677447.1
ENST00000676548.1
ENST00000519030.6
ENST00000518442.5
eukaryotic translation initiation factor 3 subunit E
chr2_-_178450764 9.25 ENST00000487082.5
protein activator of interferon induced protein kinase EIF2AK2
chr2_-_178450726 9.10 ENST00000432031.6
protein activator of interferon induced protein kinase EIF2AK2
chr3_-_182980531 9.09 ENST00000292782.9
ENST00000632685.1
defective in cullin neddylation 1 domain containing 1
chr19_+_571274 9.09 ENST00000545507.6
ENST00000346916.9
basigin (Ok blood group)
chr22_-_38700655 9.01 ENST00000216039.9
Josephin domain containing 1
chr1_+_19251786 8.99 ENST00000330263.5
MRT4 homolog, ribosome maturation factor
chr19_+_16067526 8.96 ENST00000646974.2
tropomyosin 4
chr9_+_104094557 8.91 ENST00000374787.7
structural maintenance of chromosomes 2
chr6_-_85642877 8.86 ENST00000369622.8
synaptotagmin binding cytoplasmic RNA interacting protein
chr13_+_27621779 8.68 ENST00000399697.7
ENST00000489647.4
ENST00000630983.1
ENST00000636817.1
ENST00000302979.5
ENST00000637071.1
ENST00000399696.3
RNA polymerase I and III subunit D
chr7_-_100101333 8.61 ENST00000303887.10
minichromosome maintenance complex component 7
chr2_-_9630491 8.50 ENST00000381844.8
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
chr7_-_96709855 8.43 ENST00000444799.5
ENST00000417009.5
ENST00000248566.3
SEM1 26S proteasome complex subunit
chr16_+_24539536 8.42 ENST00000568015.5
ENST00000319715.10
RB binding protein 6, ubiquitin ligase
chr2_-_169573766 8.39 ENST00000438035.5
ENST00000453929.6
FAST kinase domains 1
chr19_+_48993525 8.38 ENST00000601968.5
ENST00000596837.5
RuvB like AAA ATPase 2
chr6_-_85643778 8.08 ENST00000676637.1
ENST00000678528.1
synaptotagmin binding cytoplasmic RNA interacting protein
chr16_+_89919165 8.07 ENST00000556922.1
novel protein (MC1R-TUBB3 readthrough)
chr6_-_85643832 8.03 ENST00000677771.1
ENST00000676688.1
synaptotagmin binding cytoplasmic RNA interacting protein
chr13_+_28659100 7.83 ENST00000460403.1
ENST00000380842.5
proteasome maturation protein
chr10_+_45972482 7.68 ENST00000580018.4
translocase of inner mitochondrial membrane 23
chr7_-_7640971 7.60 ENST00000396682.6
replication protein A3
chr16_+_56730099 7.56 ENST00000563858.5
ENST00000566315.5
ENST00000308159.10
ENST00000569842.5
ENST00000569863.5
nucleoporin 93
chr13_-_113208087 7.54 ENST00000375459.5
PCI domain containing 2
chr3_-_167734832 7.52 ENST00000464360.5
ENST00000492139.5
ENST00000471885.5
ENST00000392750.7
ENST00000470131.5
programmed cell death 10
chr10_+_104254915 7.46 ENST00000445155.5
glutathione S-transferase omega 1
chr6_-_3157536 7.41 ENST00000333628.4
tubulin beta 2A class IIa
chr3_-_167734915 7.40 ENST00000497056.6
ENST00000473645.6
programmed cell death 10
chr11_-_66289125 7.29 ENST00000471387.6
ENST00000376901.9
ENST00000359461.10
Yip1 interacting factor homolog A, membrane trafficking protein
chr7_+_16646131 7.25 ENST00000415365.5
ENST00000433922.6
ENST00000630952.2
ENST00000258761.8
ENST00000405202.5
basic leucine zipper and W2 domains 2
chr2_-_178451094 7.24 ENST00000677981.1
ENST00000678845.1
ENST00000677689.1
ENST00000325748.9
ENST00000678775.1
protein activator of interferon induced protein kinase EIF2AK2
chr10_-_121975168 7.23 ENST00000369017.5
ENST00000369023.8
NSE4 homolog A, SMC5-SMC6 complex component
chr2_+_58046778 7.18 ENST00000340157.9
VRK serine/threonine kinase 2
chr10_+_75210151 7.17 ENST00000298468.9
ENST00000543351.5
voltage dependent anion channel 2
chr10_+_104254867 7.17 ENST00000369713.10
glutathione S-transferase omega 1
chr4_-_144019287 7.15 ENST00000638448.1
ENST00000513128.5
ENST00000506516.6
ENST00000429670.3
ENST00000502664.6
glycophorin B (MNS blood group)
chr11_+_112025367 7.15 ENST00000679614.1
ENST00000679878.1
ENST00000280346.11
ENST00000681339.1
ENST00000681328.1
ENST00000681316.1
ENST00000531306.2
ENST00000680331.1
ENST00000393051.5
dihydrolipoamide S-acetyltransferase
chr8_-_89984609 7.12 ENST00000519426.5
ENST00000265433.8
nibrin
chr22_-_38700920 7.12 ENST00000456626.1
ENST00000412832.1
ENST00000683374.1
Josephin domain containing 1
chr20_+_1118590 7.09 ENST00000246015.8
ENST00000335877.11
proteasome inhibitor subunit 1
chr9_+_107283256 7.06 ENST00000358015.8
RAD23 homolog B, nucleotide excision repair protein
chr1_-_246566238 7.04 ENST00000366514.5
transcription factor B2, mitochondrial
chr8_-_89984231 7.03 ENST00000517337.1
ENST00000409330.5
nibrin
chr22_+_40346461 6.96 ENST00000623632.4
ENST00000625194.4
ENST00000637666.2
ENST00000680978.1
ENST00000623063.3
ENST00000679723.1
ENST00000342312.9
adenylosuccinate lyase
chr19_+_33374312 6.90 ENST00000585933.2
CCAAT enhancer binding protein gamma
chr5_+_52787899 6.85 ENST00000274311.3
ENST00000282588.7
pelota mRNA surveillance and ribosome rescue factor
integrin subunit alpha 1
chr1_-_32817311 6.83 ENST00000373477.9
ENST00000675785.1
tyrosyl-tRNA synthetase 1
chr11_-_62671540 6.82 ENST00000532208.5
ENST00000377954.3
ENST00000431002.6
ENST00000354588.7
ENST00000415855.6
LBH domain containing 1
chr1_-_31296748 6.78 ENST00000263694.9
small nuclear ribonucleoprotein U5 subunit 40
chr1_+_218285283 6.78 ENST00000366932.4
ribosomal RNA processing 15 homolog
chr11_+_34051722 6.72 ENST00000341394.9
ENST00000389645.7
cell cycle associated protein 1
chr11_+_73787853 6.72 ENST00000310614.12
ENST00000497094.6
ENST00000411840.6
ENST00000535277.5
ENST00000398483.7
ENST00000542303.5
mitochondrial ribosomal protein L48
chr15_+_48331011 6.71 ENST00000559935.5
ENST00000559416.5
deoxyuridine triphosphatase
chr10_+_22321056 6.71 ENST00000376663.8
BMI1 proto-oncogene, polycomb ring finger
chr8_+_95133746 6.63 ENST00000315367.4
pleckstrin homology and FYVE domain containing 2
chr6_-_85642922 6.63 ENST00000616122.5
ENST00000678618.1
ENST00000678816.1
ENST00000676630.1
ENST00000678589.1
ENST00000678878.1
ENST00000676542.1
ENST00000355238.11
ENST00000678899.1
synaptotagmin binding cytoplasmic RNA interacting protein
chr17_+_35587478 6.63 ENST00000618940.4
adaptor related protein complex 2 subunit beta 1
chr17_-_59707404 6.58 ENST00000393038.3
peptidyl-tRNA hydrolase 2
chr10_+_87863595 6.54 ENST00000371953.8
phosphatase and tensin homolog
chr18_-_49491586 6.47 ENST00000584895.5
ENST00000580210.5
ENST00000579408.5
RPL17-C18orf32 readthrough
ribosomal protein L17
chr2_-_160493799 6.46 ENST00000348849.8
RNA binding motif single stranded interacting protein 1
chr12_+_65169546 6.44 ENST00000308330.3
LEM domain containing 3
chr14_-_103562257 6.44 ENST00000337322.4
ENST00000445922.2
BAG cochaperone 5
chr19_+_34365240 6.40 ENST00000586425.2
glucose-6-phosphate isomerase
chr4_-_7068033 6.40 ENST00000264954.5
GrpE like 1, mitochondrial
chr5_+_169583636 6.39 ENST00000506574.5
ENST00000515224.5
ENST00000629457.2
ENST00000508247.5
ENST00000265295.9
ENST00000513941.5
spindle apparatus coiled-coil protein 1
chr15_+_48331403 6.34 ENST00000558813.5
ENST00000331200.8
ENST00000558472.5
deoxyuridine triphosphatase
chr8_+_42391840 6.26 ENST00000520115.5
ENST00000522069.5
ENST00000522572.5
ENST00000022615.9
voltage dependent anion channel 3
chr2_+_200812185 6.25 ENST00000409226.5
ENST00000452790.6
basic leucine zipper and W2 domains 1
chrX_+_150983350 6.15 ENST00000455596.5
ENST00000448905.6
high mobility group box 3
chr2_+_58046625 6.14 ENST00000412104.6
ENST00000440705.6
VRK serine/threonine kinase 2
chr22_-_42090743 6.14 ENST00000498737.8
ENST00000617763.1
NADH:ubiquinone oxidoreductase subunit A6
chr16_+_1309714 6.05 ENST00000566587.5
ubiquitin conjugating enzyme E2 I
chr11_+_65919261 5.97 ENST00000525501.5
DR1 associated protein 1
chr7_-_93890744 5.95 ENST00000650573.1
ENST00000222543.11
ENST00000649913.1
ENST00000647793.1
tissue factor pathway inhibitor 2
chr2_-_9630946 5.88 ENST00000446619.1
ENST00000238081.8
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
chr10_+_84139491 5.86 ENST00000372134.6
growth hormone inducible transmembrane protein
chr21_-_37073170 5.75 ENST00000399098.5
phosphatidylinositol glycan anchor biosynthesis class P
chr5_-_134632769 5.72 ENST00000505758.5
ENST00000439578.5
ENST00000502286.1
ENST00000402673.7
secretion associated Ras related GTPase 1B
chr18_+_32092610 5.69 ENST00000578107.5
ENST00000257190.9
ENST00000580499.1
ring finger protein 138
chr11_+_65919331 5.68 ENST00000376991.6
DR1 associated protein 1
chr2_-_169573856 5.63 ENST00000453153.7
ENST00000445210.1
FAST kinase domains 1
chr17_-_63773534 5.61 ENST00000403162.7
ENST00000582252.1
ENST00000225726.10
coiled-coil domain containing 47
chr4_+_139301478 5.59 ENST00000296543.10
ENST00000398947.1
N-alpha-acetyltransferase 15, NatA auxiliary subunit
chr9_-_125650417 5.58 ENST00000420643.5
MAPK associated protein 1
chr4_+_17810945 5.50 ENST00000251496.7
non-SMC condensin I complex subunit G
chr1_-_244451896 5.48 ENST00000366535.4
adenylosuccinate synthase 2
chr9_-_92293674 5.45 ENST00000683679.1
ENST00000683565.1
ENST00000684557.1
ENST00000682578.1
ENST00000443024.7
ENST00000375643.7
ENST00000683469.1
isoleucyl-tRNA synthetase 1
chr4_-_151015713 5.42 ENST00000357115.9
LPS responsive beige-like anchor protein
chr6_-_130956371 5.37 ENST00000639623.1
ENST00000525193.5
ENST00000527659.5
erythrocyte membrane protein band 4.1 like 2
chr13_+_72727749 5.33 ENST00000652266.1
ENST00000651477.1
ENST00000613797.4
BORA aurora kinase A activator
chr9_+_113221528 5.27 ENST00000374212.5
solute carrier family 31 member 1
chr11_+_112226345 5.27 ENST00000280362.8
ENST00000525803.1
6-pyruvoyltetrahydropterin synthase
chrX_+_132023294 5.26 ENST00000481105.5
ENST00000354719.10
ENST00000394334.7
ENST00000394335.6
serine/threonine kinase 26
chr6_+_63521738 5.25 ENST00000648894.1
ENST00000639568.2
protein tyrosine phosphatase 4A1
chr11_+_120240135 5.21 ENST00000543440.7
POU class 2 homeobox 3
chr21_-_37073019 5.13 ENST00000360525.9
phosphatidylinositol glycan anchor biosynthesis class P
chr12_-_56315890 5.11 ENST00000551286.1
ENST00000549318.5
canopy FGF signaling regulator 2
novel protein
chr3_-_128123765 5.10 ENST00000322623.10
RuvB like AAA ATPase 1
chr14_-_50668287 5.08 ENST00000556735.1
ENST00000324679.5
salvador family WW domain containing protein 1
chr7_-_93890160 5.02 ENST00000451238.1
tissue factor pathway inhibitor 2
chr15_+_88639009 4.94 ENST00000306072.10
interferon stimulated exonuclease gene 20
chr14_+_67360313 4.85 ENST00000256383.11
eukaryotic translation initiation factor 2 subunit alpha
chr15_-_22980334 4.85 ENST00000610365.4
ENST00000617928.5
ENST00000611832.4
cytoplasmic FMR1 interacting protein 1
chr16_-_58198059 4.83 ENST00000262506.8
casein kinase 2 alpha 2
chr1_-_205775182 4.82 ENST00000446390.6
RAB29, member RAS oncogene family
chr2_-_37672448 4.80 ENST00000611976.1
CDC42 effector protein 3
chr15_+_88638947 4.78 ENST00000559876.2
interferon stimulated exonuclease gene 20
chr9_+_104094260 4.78 ENST00000286398.11
ENST00000440179.5
ENST00000374793.8
structural maintenance of chromosomes 2
chr14_-_68937942 4.77 ENST00000684182.1
actinin alpha 1
chr15_+_51829644 4.77 ENST00000308580.12
tropomodulin 3
chr16_+_30053123 4.75 ENST00000395248.6
ENST00000575627.5
ENST00000566897.6
ENST00000568435.6
ENST00000338110.11
ENST00000562240.1
novel protein
chr1_-_153977260 4.75 ENST00000428469.1
jumping translocation breakpoint
chr9_-_127874964 4.71 ENST00000373156.5
adenylate kinase 1
chr10_+_99732211 4.71 ENST00000370476.10
ENST00000370472.4
cutC copper transporter
chr1_+_231528541 4.69 ENST00000413309.3
ENST00000366639.9
translin associated factor X
chr19_+_7534711 4.68 ENST00000414982.7
ENST00000450331.7
patatin like phospholipase domain containing 6
chr18_-_49492305 4.65 ENST00000615479.4
ENST00000583637.5
ENST00000618613.5
ENST00000615760.4
ENST00000578528.1
ENST00000578532.5
ENST00000580387.5
ENST00000579248.5
ENST00000580261.6
ENST00000581373.5
ENST00000618619.4
ENST00000617346.4
ENST00000583036.5
ENST00000332968.11
ribosomal protein L17
RPL17-C18orf32 readthrough
chr21_-_43107553 4.62 ENST00000380276.6
ENST00000291552.9
U2 small nuclear RNA auxiliary factor 1
chr6_+_37354046 4.46 ENST00000487950.1
ENST00000469731.5
ring finger protein 8
chr21_-_6499202 4.45 ENST00000619610.2
ENST00000610664.5
ENST00000639996.1
U2 small nuclear RNA auxiliary factor 1 like 5
chr5_+_271637 4.44 ENST00000264933.9
ENST00000505221.5
ENST00000509581.5
ENST00000507528.5
programmed cell death 6
chr4_+_37960397 4.44 ENST00000504686.2
pituitary tumor-transforming 2
chr2_-_3377790 4.40 ENST00000443925.6
ENST00000441271.1
ENST00000444776.1
ENST00000382125.9
ENST00000398659.8
EARP complex and GARP complex interacting protein 1
chr11_+_35180279 4.34 ENST00000531873.5
CD44 molecule (Indian blood group)
chr11_+_35180342 4.29 ENST00000639002.1
CD44 molecule (Indian blood group)
chr15_-_90234046 4.29 ENST00000612800.1
calcium and integrin binding 1
chr19_-_14518383 4.29 ENST00000254322.3
ENST00000595139.2
DnaJ heat shock protein family (Hsp40) member B1
chr22_-_42519782 4.28 ENST00000323013.7
ribosomal RNA processing 7 homolog A
chr13_+_72727910 4.27 ENST00000377814.6
ENST00000390667.11
BORA aurora kinase A activator
chr11_-_33736406 4.27 ENST00000533403.6
ENST00000395850.9
ENST00000426650.7
ENST00000528700.2
ENST00000642928.2
ENST00000651785.1
ENST00000643183.1
ENST00000527577.5
ENST00000652086.1
CD59 molecule (CD59 blood group)
chr21_+_17513003 4.22 ENST00000284878.12
ENST00000400166.5
CXADR Ig-like cell adhesion molecule
chr3_+_125969214 4.17 ENST00000508088.1
rhophilin associated tail protein 1B
chr17_+_35587239 4.15 ENST00000621914.4
ENST00000621668.4
ENST00000616681.4
ENST00000612035.4
ENST00000610402.5
ENST00000614600.4
ENST00000590432.5
ENST00000612116.5
adaptor related protein complex 2 subunit beta 1
chr14_-_24213446 4.14 ENST00000530611.1
ENST00000347519.12
ENST00000530996.5
novel protein
charged multivesicular body protein 4A
chr1_+_186375813 4.12 ENST00000419367.8
ENST00000287859.11
ENST00000367470.8
odr-4 GPCR localization factor homolog
chr4_-_54064586 4.10 ENST00000263921.8
cysteine rich hydrophobic domain 2
chr16_+_67882449 4.06 ENST00000577105.1
ENST00000573985.5
ENST00000572067.1
enhancer of mRNA decapping 4
novel transcript
chr19_+_7534242 4.04 ENST00000545201.6
patatin like phospholipase domain containing 6
chr3_-_121545962 4.03 ENST00000264233.6
DNA polymerase theta
chr6_-_75243770 4.01 ENST00000472311.6
ENST00000460985.1
ENST00000377978.3
ENST00000684430.1
ENST00000509698.6
cytochrome c oxidase subunit 7A2
chrX_-_103502853 3.92 ENST00000372633.1
RAB40A, member RAS oncogene family
chr7_+_43583091 3.89 ENST00000319357.6
serine/threonine kinase 17a
chr11_+_834466 3.88 ENST00000528011.2
CD151 molecule (Raph blood group)
chr17_-_79839387 3.85 ENST00000448310.1
ENST00000269397.9
chromobox 4
chr17_-_15684288 3.84 ENST00000416464.6
ENST00000578237.5
ENST00000581200.1
ENST00000649191.2
tripartite motif containing 16
chr17_-_19362732 3.82 ENST00000395616.7
B9 domain containing 1
chr8_+_55773424 3.81 ENST00000260129.6
trimethylguanosine synthase 1
chr15_-_84716153 3.80 ENST00000455959.7
SEC11 homolog A, signal peptidase complex subunit
chr5_+_271616 3.80 ENST00000614778.4
ENST00000618970.4
ENST00000628729.2
programmed cell death 6
chr20_+_3846799 3.76 ENST00000416600.6
ENST00000428216.4
mitochondrial antiviral signaling protein
chr1_-_206921987 3.72 ENST00000530505.1
ENST00000442471.4
Fc fragment of IgM receptor
chr17_-_1684807 3.71 ENST00000577001.1
ENST00000572621.5
ENST00000304992.11
pre-mRNA processing factor 8
chr15_+_40695423 3.69 ENST00000526763.6
ENST00000532743.6
RAD51 recombinase
chr12_+_12891554 3.65 ENST00000014914.6
G protein-coupled receptor class C group 5 member A
chr11_+_63938971 3.61 ENST00000539656.5
ENST00000377793.9
N-alpha-acetyltransferase 40, NatD catalytic subunit
chr8_+_60678705 3.57 ENST00000423902.7
chromodomain helicase DNA binding protein 7
chr17_-_58352139 3.56 ENST00000225504.8
SPT4 homolog, DSIF elongation factor subunit
chrX_-_63785510 3.56 ENST00000437457.6
ENST00000374878.5
ENST00000623517.3
Cdc42 guanine nucleotide exchange factor 9
chr6_+_53794948 3.55 ENST00000370888.6
leucine rich repeat containing 1
chr19_+_9827886 3.53 ENST00000358666.7
ENST00000590068.1
ENST00000593087.1
ENST00000586895.6
ubiquitin like 5
chr19_+_54105923 3.52 ENST00000420296.1
NADH:ubiquinone oxidoreductase subunit A3
chr1_+_25272439 3.50 ENST00000648012.1
Rh blood group D antigen
chr8_+_143018479 3.49 ENST00000429120.6
ENST00000521699.5
ENST00000520531.5
ENST00000520466.5
ENST00000521003.5
ENST00000522528.5
ENST00000292494.11
ENST00000522971.5
ENST00000519611.5
ENST00000521182.5
ENST00000519546.5
ENST00000523847.5
ENST00000522024.1
lymphocyte antigen 6 family member E
chr1_-_165768848 3.46 ENST00000367881.11
ENST00000464650.5
ENST00000612311.4
ENST00000628579.1
transmembrane and coiled-coil domains 1
chr12_-_107093509 3.46 ENST00000008527.10
cryptochrome circadian regulator 1
chr22_-_32412207 3.44 ENST00000216038.6
RNA 2',3'-cyclic phosphate and 5'-OH ligase

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 35.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
6.0 23.9 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
4.9 14.6 GO:0014810 positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014810)
4.5 27.0 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
4.4 13.1 GO:0046080 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
4.1 24.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
3.5 10.4 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466) mitochondrial membrane fission(GO:0090149)
3.2 9.7 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
3.2 9.5 GO:0046452 dihydrofolate metabolic process(GO:0046452)
2.8 14.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
2.7 15.9 GO:0015853 adenine transport(GO:0015853)
2.5 7.6 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
2.5 34.9 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
2.4 12.0 GO:0035549 positive regulation of interferon-beta secretion(GO:0035549)
2.4 11.8 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
2.3 7.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
2.2 10.8 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
2.1 27.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
2.1 8.4 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
2.0 18.3 GO:0006167 AMP biosynthetic process(GO:0006167) 'de novo' IMP biosynthetic process(GO:0006189)
2.0 30.3 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
2.0 9.8 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
1.8 10.9 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
1.6 6.5 GO:1903984 rhythmic synaptic transmission(GO:0060024) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
1.6 4.8 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
1.6 6.3 GO:1903755 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)
1.5 6.2 GO:1901143 insulin catabolic process(GO:1901143)
1.5 7.5 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
1.5 29.1 GO:0000022 mitotic spindle elongation(GO:0000022)
1.5 5.8 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
1.4 9.8 GO:0008215 spermine metabolic process(GO:0008215)
1.4 6.8 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
1.3 22.6 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
1.3 4.0 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
1.3 6.4 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
1.2 16.2 GO:0006983 ER overload response(GO:0006983)
1.2 4.8 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
1.2 3.6 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
1.2 3.5 GO:2000832 negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
1.1 5.6 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
1.1 4.3 GO:0007113 endomitotic cell cycle(GO:0007113)
1.1 6.4 GO:0009438 methylglyoxal metabolic process(GO:0009438)
1.1 4.2 GO:0098904 regulation of AV node cell action potential(GO:0098904)
1.0 9.4 GO:1902416 positive regulation of mRNA binding(GO:1902416)
1.0 3.1 GO:0060739 mesenchymal-epithelial cell signaling involved in prostate gland development(GO:0060739)
1.0 3.0 GO:0051231 spindle elongation(GO:0051231)
1.0 13.3 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.9 2.8 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.9 14.1 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.9 5.3 GO:0072719 cellular response to cisplatin(GO:0072719)
0.9 5.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.9 4.3 GO:0001971 negative regulation of activation of membrane attack complex(GO:0001971)
0.8 8.4 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.8 4.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.8 9.1 GO:0046689 response to mercury ion(GO:0046689)
0.8 8.2 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.8 6.6 GO:2000210 positive regulation of anoikis(GO:2000210)
0.8 1.6 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.8 5.7 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.8 4.8 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.7 7.3 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.7 6.4 GO:0034501 protein localization to kinetochore(GO:0034501)
0.7 25.0 GO:0034080 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.7 3.5 GO:0035900 response to isolation stress(GO:0035900)
0.7 6.9 GO:0043353 enucleate erythrocyte differentiation(GO:0043353) positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.7 8.6 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.7 4.6 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.7 3.3 GO:0012502 induction of programmed cell death(GO:0012502) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501)
0.6 3.2 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.6 1.9 GO:0015798 myo-inositol transport(GO:0015798)
0.6 9.1 GO:0045116 protein neddylation(GO:0045116)
0.6 2.4 GO:0061009 common bile duct development(GO:0061009)
0.6 1.1 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.5 1.6 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.5 10.8 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.5 2.0 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.5 4.0 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.5 7.8 GO:0043248 proteasome assembly(GO:0043248)
0.5 1.4 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.4 2.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.4 2.2 GO:0032057 negative regulation of translational initiation in response to stress(GO:0032057)
0.4 3.6 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.4 12.9 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.4 2.7 GO:0031444 slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.4 10.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.4 3.8 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.4 1.1 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of nephron tubule epithelial cell differentiation(GO:0072183) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308) negative regulation of epithelial cell differentiation involved in kidney development(GO:2000697)
0.4 16.2 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.4 9.5 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.4 5.1 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.4 7.6 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.4 1.8 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.4 23.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.4 2.8 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.4 4.9 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.3 7.0 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.3 1.0 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.3 1.0 GO:0090166 Golgi disassembly(GO:0090166)
0.3 8.7 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.3 1.0 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.3 3.9 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.3 1.3 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.3 5.4 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.3 1.6 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.3 0.9 GO:0045645 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
0.3 1.2 GO:0072106 regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107)
0.3 3.6 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.3 13.2 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.3 5.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.3 2.6 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.3 3.7 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.3 2.0 GO:0051661 maintenance of centrosome location(GO:0051661)
0.3 0.8 GO:0032304 negative regulation of icosanoid secretion(GO:0032304)
0.3 1.4 GO:0040031 snRNA modification(GO:0040031)
0.3 3.1 GO:0051451 myoblast migration(GO:0051451)
0.3 13.4 GO:0006294 nucleotide-excision repair, preincision complex assembly(GO:0006294)
0.3 18.2 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.3 2.9 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.3 4.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.3 1.3 GO:0050915 iron chelate transport(GO:0015688) siderophore transport(GO:0015891) sensory perception of sour taste(GO:0050915)
0.3 1.6 GO:0061743 motor learning(GO:0061743)
0.3 9.3 GO:2000816 negative regulation of mitotic sister chromatid separation(GO:2000816)
0.3 3.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.3 3.4 GO:0046040 IMP metabolic process(GO:0046040)
0.3 1.8 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.3 3.3 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.3 9.6 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.3 6.8 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.2 3.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.2 9.0 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.2 5.9 GO:0055070 copper ion homeostasis(GO:0055070)
0.2 6.5 GO:0001825 blastocyst formation(GO:0001825)
0.2 3.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.2 0.7 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.2 0.9 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.2 6.3 GO:0006465 signal peptide processing(GO:0006465)
0.2 0.7 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2 3.0 GO:0070986 left/right axis specification(GO:0070986)
0.2 4.8 GO:0051639 actin filament network formation(GO:0051639) actin crosslink formation(GO:0051764)
0.2 2.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.2 7.1 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.2 7.9 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.2 1.4 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.2 1.2 GO:0044351 macropinocytosis(GO:0044351)
0.2 2.7 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.2 3.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.2 2.0 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 0.9 GO:0097338 response to clozapine(GO:0097338)
0.2 2.4 GO:0003334 keratinocyte development(GO:0003334)
0.2 1.2 GO:0006689 ganglioside catabolic process(GO:0006689)
0.1 1.9 GO:0055026 negative regulation of cardiac muscle tissue development(GO:0055026)
0.1 14.8 GO:0045333 cellular respiration(GO:0045333)
0.1 2.3 GO:0016540 protein autoprocessing(GO:0016540)
0.1 13.8 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.1 2.8 GO:0001765 membrane raft assembly(GO:0001765)
0.1 7.2 GO:1903146 regulation of mitophagy(GO:1903146)
0.1 3.8 GO:0036260 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.1 1.2 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.1 8.0 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 10.4 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.1 2.7 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 14.7 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.1 2.7 GO:0002360 T cell lineage commitment(GO:0002360)
0.1 1.0 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 3.7 GO:0005980 glycogen catabolic process(GO:0005980)
0.1 6.1 GO:0032392 DNA geometric change(GO:0032392)
0.1 2.1 GO:0030488 tRNA methylation(GO:0030488)
0.1 6.7 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.8 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 8.1 GO:0006903 vesicle targeting(GO:0006903)
0.1 8.9 GO:0008637 apoptotic mitochondrial changes(GO:0008637)
0.1 2.1 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.1 1.1 GO:0097062 dendritic spine maintenance(GO:0097062)
0.1 1.8 GO:0048305 immunoglobulin secretion(GO:0048305)
0.1 6.5 GO:0036498 IRE1-mediated unfolded protein response(GO:0036498)
0.1 2.6 GO:0006400 tRNA modification(GO:0006400)
0.1 2.4 GO:0043928 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291) exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1 8.5 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.3 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 1.5 GO:0090527 actin filament reorganization(GO:0090527)
0.1 4.7 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.1 4.5 GO:2001243 negative regulation of intrinsic apoptotic signaling pathway(GO:2001243)
0.1 5.5 GO:0061053 somite development(GO:0061053)
0.1 0.2 GO:0060750 epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.1 0.5 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 0.2 GO:1903248 negative regulation of cardiac muscle adaptation(GO:0010616) regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) regulation of cellular amino acid biosynthetic process(GO:2000282) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.1 5.0 GO:0006968 cellular defense response(GO:0006968)
0.1 3.1 GO:1900006 positive regulation of dendrite development(GO:1900006)
0.1 0.4 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.1 2.4 GO:0015949 nucleobase-containing small molecule interconversion(GO:0015949)
0.1 2.8 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.5 GO:0006591 ornithine metabolic process(GO:0006591)
0.0 0.9 GO:0050849 negative regulation of calcium-mediated signaling(GO:0050849)
0.0 5.5 GO:0007224 smoothened signaling pathway(GO:0007224)
0.0 2.7 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 1.2 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 1.3 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.1 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.0 1.0 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.1 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 2.9 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.3 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 1.0 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0 4.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.9 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.4 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 2.0 GO:1903169 regulation of calcium ion transmembrane transport(GO:1903169)
0.0 0.6 GO:0045652 regulation of megakaryocyte differentiation(GO:0045652)
0.0 0.8 GO:0021766 hippocampus development(GO:0021766)
0.0 0.4 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.0 0.2 GO:0048240 sperm capacitation(GO:0048240)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.8 30.3 GO:0000796 condensin complex(GO:0000796)
3.5 31.6 GO:0097452 GAIT complex(GO:0097452)
1.8 24.0 GO:0042555 MCM complex(GO:0042555)
1.8 9.1 GO:0089701 U2AF(GO:0089701)
1.8 7.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
1.8 7.1 GO:0071942 XPC complex(GO:0071942)
1.7 7.0 GO:0020003 symbiont-containing vacuole(GO:0020003)
1.7 6.8 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
1.6 23.0 GO:0070938 contractile ring(GO:0070938)
1.6 6.4 GO:0001405 presequence translocase-associated import motor(GO:0001405)
1.6 25.6 GO:0070578 RISC-loading complex(GO:0070578)
1.6 6.3 GO:1990356 sumoylated E2 ligase complex(GO:1990356)
1.5 14.5 GO:0097255 R2TP complex(GO:0097255)
1.3 27.0 GO:0031616 spindle pole centrosome(GO:0031616)
1.3 13.0 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
1.3 14.2 GO:0030870 Mre11 complex(GO:0030870)
1.2 4.8 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
1.2 7.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
1.1 1.1 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
1.1 10.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
1.0 23.1 GO:0046930 pore complex(GO:0046930)
0.9 7.7 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.8 5.6 GO:0031415 NatA complex(GO:0031415)
0.8 12.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.8 8.6 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.7 3.6 GO:0032044 DSIF complex(GO:0032044)
0.7 6.3 GO:0005787 signal peptidase complex(GO:0005787)
0.6 9.0 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.6 7.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.6 3.4 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.5 3.3 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.5 8.6 GO:0035102 PRC1 complex(GO:0035102)
0.5 4.8 GO:0044294 dendritic growth cone(GO:0044294)
0.5 6.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.5 3.2 GO:0032279 asymmetric synapse(GO:0032279)
0.5 9.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.5 14.2 GO:0035861 site of double-strand break(GO:0035861)
0.5 6.5 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.5 2.0 GO:0044307 dendritic branch(GO:0044307)
0.5 10.8 GO:0036020 endolysosome membrane(GO:0036020)
0.5 9.1 GO:0036038 MKS complex(GO:0036038)
0.5 8.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.5 11.8 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.4 2.2 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.4 10.5 GO:0005682 U5 snRNP(GO:0005682)
0.4 37.0 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.4 3.7 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.4 23.7 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.4 2.8 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.3 6.2 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.3 9.1 GO:0002080 acrosomal membrane(GO:0002080)
0.3 4.1 GO:0000815 ESCRT III complex(GO:0000815)
0.3 5.4 GO:0008091 spectrin(GO:0008091)
0.3 2.2 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.3 1.4 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.3 1.6 GO:0070187 telosome(GO:0070187)
0.3 24.1 GO:0035580 specific granule lumen(GO:0035580)
0.3 5.6 GO:0031932 TORC2 complex(GO:0031932)
0.3 6.1 GO:0030056 hemidesmosome(GO:0030056)
0.2 1.0 GO:0070876 SOSS complex(GO:0070876)
0.2 16.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.2 7.1 GO:0005839 proteasome core complex(GO:0005839)
0.2 6.6 GO:0005865 striated muscle thin filament(GO:0005865)
0.2 6.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.2 16.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.2 5.7 GO:0031143 pseudopodium(GO:0031143)
0.2 2.0 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.2 3.9 GO:0032433 filopodium tip(GO:0032433)
0.2 4.3 GO:0030686 90S preribosome(GO:0030686)
0.2 10.7 GO:0015030 Cajal body(GO:0015030)
0.2 2.0 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.2 3.2 GO:0005652 nuclear lamina(GO:0005652)
0.2 3.9 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.1 14.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 3.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 6.9 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 3.3 GO:0032982 myosin filament(GO:0032982)
0.1 5.0 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.1 4.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 2.2 GO:0044453 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 9.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 3.2 GO:0045171 intercellular bridge(GO:0045171)
0.1 4.8 GO:0031519 PcG protein complex(GO:0031519)
0.1 1.2 GO:0033162 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.1 14.8 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 3.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 0.4 GO:0070552 BRISC complex(GO:0070552)
0.1 10.7 GO:0031514 motile cilium(GO:0031514)
0.1 1.8 GO:0016460 myosin II complex(GO:0016460)
0.1 2.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.1 1.2 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 6.2 GO:0016234 inclusion body(GO:0016234)
0.1 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.1 0.6 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.7 GO:0008180 COP9 signalosome(GO:0008180)
0.0 7.6 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 2.4 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 6.3 GO:0030496 midbody(GO:0030496)
0.0 5.8 GO:0001650 fibrillar center(GO:0001650)
0.0 3.1 GO:0005643 nuclear pore(GO:0005643)
0.0 1.1 GO:0005921 gap junction(GO:0005921)
0.0 2.6 GO:0060170 ciliary membrane(GO:0060170)
0.0 4.4 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:1990031 pinceau fiber(GO:1990031)
0.0 7.3 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.2 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.0 1.0 GO:0005801 cis-Golgi network(GO:0005801)
0.0 2.0 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.1 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 4.0 GO:0016607 nuclear speck(GO:0016607)
0.0 0.9 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 15.7 GO:0005739 mitochondrion(GO:0005739)
0.0 0.4 GO:0031941 filamentous actin(GO:0031941)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.4 13.1 GO:0004170 dUTP diphosphatase activity(GO:0004170)
3.7 11.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
3.2 9.7 GO:0008859 exoribonuclease II activity(GO:0008859)
2.9 14.6 GO:0050610 glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
2.9 23.1 GO:0015288 porin activity(GO:0015288)
2.7 10.9 GO:0031493 nucleosomal histone binding(GO:0031493)
2.7 13.5 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
2.7 24.1 GO:0016842 amidine-lyase activity(GO:0016842)
2.6 7.7 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
2.6 25.6 GO:0070883 pre-miRNA binding(GO:0070883)
2.4 9.5 GO:0004146 dihydrofolate reductase activity(GO:0004146)
2.2 6.5 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717)
2.1 6.2 GO:0031626 beta-endorphin binding(GO:0031626)
1.9 13.0 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
1.8 7.1 GO:0016418 S-acetyltransferase activity(GO:0016418)
1.8 5.3 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
1.6 6.4 GO:0043515 kinetochore binding(GO:0043515)
1.5 11.8 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
1.4 4.3 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
1.3 6.6 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
1.3 3.8 GO:0032089 NACHT domain binding(GO:0032089)
1.2 16.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
1.2 10.9 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
1.2 7.0 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
1.2 4.6 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
1.1 3.4 GO:0050146 nucleoside phosphotransferase activity(GO:0050146)
1.1 23.9 GO:0008242 omega peptidase activity(GO:0008242)
1.0 4.0 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
1.0 7.7 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.9 2.8 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.9 31.6 GO:0008143 poly(A) binding(GO:0008143)
0.9 3.6 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.9 6.8 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.8 6.8 GO:0008158 hedgehog receptor activity(GO:0008158)
0.8 38.2 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.8 12.7 GO:0001054 RNA polymerase I activity(GO:0001054)
0.8 2.3 GO:0048030 disaccharide binding(GO:0048030)
0.7 3.7 GO:0030620 U1 snRNA binding(GO:0030619) U2 snRNA binding(GO:0030620)
0.7 1.3 GO:0000405 bubble DNA binding(GO:0000405)
0.6 3.2 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.6 6.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.6 3.9 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
0.6 4.5 GO:0050733 RS domain binding(GO:0050733)
0.5 10.4 GO:0051400 BH domain binding(GO:0051400)
0.5 23.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.5 5.4 GO:0042731 PH domain binding(GO:0042731)
0.5 4.2 GO:0071253 connexin binding(GO:0071253)
0.5 32.7 GO:0019894 kinesin binding(GO:0019894)
0.5 4.8 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.5 9.1 GO:0097602 cullin family protein binding(GO:0097602)
0.5 9.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.5 10.8 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.5 1.8 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.5 22.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.4 2.6 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.4 5.3 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.4 8.2 GO:0043495 protein anchor(GO:0043495)
0.4 82.7 GO:0047485 protein N-terminus binding(GO:0047485)
0.4 1.2 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.4 13.0 GO:0008301 DNA binding, bending(GO:0008301)
0.4 1.2 GO:0009032 thymidine phosphorylase activity(GO:0009032) pyrimidine-nucleoside phosphorylase activity(GO:0016154)
0.4 1.2 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.4 3.1 GO:0045545 syndecan binding(GO:0045545)
0.4 3.8 GO:0050700 CARD domain binding(GO:0050700)
0.4 2.2 GO:1904047 S-adenosyl-L-methionine binding(GO:1904047)
0.4 3.7 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.3 3.5 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.3 2.7 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.3 1.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.3 1.3 GO:0003883 CTP synthase activity(GO:0003883)
0.3 10.7 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.3 12.8 GO:0031369 translation initiation factor binding(GO:0031369)
0.3 17.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.3 11.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 8.2 GO:0017166 vinculin binding(GO:0017166)
0.3 7.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.3 1.2 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.3 2.9 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.3 0.8 GO:0097258 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.3 3.8 GO:0019789 SUMO transferase activity(GO:0019789)
0.3 7.1 GO:0070628 proteasome binding(GO:0070628)
0.3 6.2 GO:0005537 mannose binding(GO:0005537)
0.3 3.5 GO:0031386 protein tag(GO:0031386)
0.3 5.8 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.2 2.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 6.6 GO:0005523 tropomyosin binding(GO:0005523)
0.2 28.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.2 3.5 GO:0009881 photoreceptor activity(GO:0009881)
0.2 5.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 7.6 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.2 2.4 GO:0038132 neuregulin binding(GO:0038132)
0.2 3.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 3.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.2 5.0 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 2.4 GO:0004017 adenylate kinase activity(GO:0004017)
0.2 13.6 GO:0008307 structural constituent of muscle(GO:0008307)
0.2 1.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 1.2 GO:0034617 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714) tetrahydrobiopterin binding(GO:0034617)
0.1 1.0 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 7.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 2.1 GO:0043422 protein kinase B binding(GO:0043422)
0.1 4.3 GO:0001848 complement binding(GO:0001848)
0.1 1.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 1.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.4 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 4.3 GO:0001671 ATPase activator activity(GO:0001671)
0.1 11.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 3.6 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.1 2.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.5 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 3.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 10.1 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.1 18.4 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.1 7.7 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 3.0 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.1 1.6 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 2.1 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.1 0.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 2.0 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.1 6.4 GO:0031490 chromatin DNA binding(GO:0031490)
0.1 0.9 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.1 10.5 GO:0005262 calcium channel activity(GO:0005262)
0.1 2.8 GO:0032947 protein complex scaffold(GO:0032947)
0.1 7.5 GO:0008565 protein transporter activity(GO:0008565)
0.1 1.1 GO:0005522 profilin binding(GO:0005522)
0.1 1.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 1.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 11.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 1.0 GO:0035198 miRNA binding(GO:0035198)
0.1 1.1 GO:0001968 fibronectin binding(GO:0001968)
0.0 1.1 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.9 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.9 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 4.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.6 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 1.6 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.5 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 3.9 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 6.6 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 4.1 GO:0042393 histone binding(GO:0042393)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 4.0 GO:0030414 peptidase inhibitor activity(GO:0030414)
0.0 0.3 GO:0048156 tau protein binding(GO:0048156)
0.0 2.8 GO:0044325 ion channel binding(GO:0044325)
0.0 0.8 GO:0097110 scaffold protein binding(GO:0097110)
0.0 1.0 GO:0051117 ATPase binding(GO:0051117)
0.0 1.9 GO:0070851 growth factor receptor binding(GO:0070851)
0.0 0.5 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 1.6 GO:0003774 motor activity(GO:0003774)
0.0 3.4 GO:0045296 cadherin binding(GO:0045296)
0.0 2.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 30.3 PID AURORA B PATHWAY Aurora B signaling
0.7 45.1 PID ATR PATHWAY ATR signaling pathway
0.6 38.7 PID PLK1 PATHWAY PLK1 signaling events
0.6 27.0 PID AURORA A PATHWAY Aurora A signaling
0.5 16.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.4 54.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.3 12.1 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.3 6.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.3 25.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.2 8.6 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 3.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.2 3.2 PID MYC PATHWAY C-MYC pathway
0.2 10.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 10.2 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.2 12.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.2 4.8 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.2 4.9 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 13.3 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 5.6 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.2 2.7 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.2 2.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.2 4.6 PID ATM PATHWAY ATM pathway
0.1 11.9 PID E2F PATHWAY E2F transcription factor network
0.1 0.8 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 1.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 3.8 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 3.4 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 1.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 1.2 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.1 3.3 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 3.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.2 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 1.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.1 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.3 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.7 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.2 PID P73PATHWAY p73 transcription factor network
0.0 0.1 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 24.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
1.2 18.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
1.1 25.0 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
1.0 25.7 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.7 14.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.6 12.0 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.6 12.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.5 13.9 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.5 10.8 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.4 4.9 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.4 14.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.4 10.8 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.4 8.7 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.4 9.3 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.4 17.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.4 14.2 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.4 8.4 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.4 10.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.4 8.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.3 6.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.3 3.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.3 9.3 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.3 8.9 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.3 8.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.3 23.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.3 6.6 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.3 5.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 7.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.3 7.1 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.3 3.0 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.2 23.2 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.2 6.7 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.2 5.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.2 5.3 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 1.6 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.2 3.6 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.2 5.1 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.2 14.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 3.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 1.9 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.2 6.0 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2 18.0 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.2 2.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.2 9.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 4.8 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 14.5 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 2.9 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 6.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 2.7 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.1 3.1 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.4 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.1 7.0 REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.1 5.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 4.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 7.1 REACTOME ORC1 REMOVAL FROM CHROMATIN Genes involved in Orc1 removal from chromatin
0.1 10.4 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.0 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.9 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.1 2.9 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.1 3.2 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 2.0 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.1 3.4 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 3.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 5.5 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.1 3.9 REACTOME PI METABOLISM Genes involved in PI Metabolism
0.1 1.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 2.0 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 2.7 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 1.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 3.4 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.9 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 1.2 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 1.2 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 1.0 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 3.0 REACTOME CELL JUNCTION ORGANIZATION Genes involved in Cell junction organization
0.0 1.1 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 3.1 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.4 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.0 REACTOME SIGNALING BY ERBB4 Genes involved in Signaling by ERBB4
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.4 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases