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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ESR1

Z-value: 5.26

Motif logo

Transcription factors associated with ESR1

Gene Symbol Gene ID Gene Info
ENSG00000091831.24 ESR1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ESR1hg38_v1_chr6_+_151807674_1518076920.269.7e-05Click!

Activity profile of ESR1 motif

Sorted Z-values of ESR1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ESR1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr22_+_22758698 51.15 ENST00000390312.2
immunoglobulin lambda variable 2-14
chr22_+_22906342 34.34 ENST00000390325.2
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr22_+_22899481 32.92 ENST00000390322.2
immunoglobulin lambda joining 2
chr2_-_89100352 32.20 ENST00000479981.1
immunoglobulin kappa variable 1-16
chr2_-_88992903 31.08 ENST00000495489.1
immunoglobulin kappa variable 1-8
chr22_+_22904850 30.32 ENST00000390324.2
immunoglobulin lambda joining 3
chr22_+_22895368 29.80 ENST00000390321.2
immunoglobulin lambda constant 1
chr22_+_22900976 28.90 ENST00000390323.2
immunoglobulin lambda constant 2
chr2_-_89213917 28.51 ENST00000498435.1
immunoglobulin kappa variable 1-27
chr14_-_105588322 23.05 ENST00000497872.4
ENST00000390539.2
immunoglobulin heavy constant alpha 2 (A2m marker)
chr22_+_22792485 22.73 ENST00000390314.2
immunoglobulin lambda variable 2-11
chr22_+_22697789 22.61 ENST00000390306.2
immunoglobulin lambda variable 2-23
chr22_+_22822658 20.96 ENST00000620395.2
immunoglobulin lambda variable 2-8
chr14_-_105708627 20.11 ENST00000641837.1
ENST00000390547.3
immunoglobulin heavy constant alpha 1
chr2_-_89010515 20.06 ENST00000493819.1
immunoglobulin kappa variable 1-9
chr2_-_88979016 19.73 ENST00000390247.2
immunoglobulin kappa variable 3-7 (non-functional)
chr3_-_46464868 18.84 ENST00000417439.5
ENST00000231751.9
ENST00000431944.1
lactotransferrin
chr22_+_22704265 18.68 ENST00000390307.2
immunoglobulin lambda variable 3-22
chr2_-_89117844 18.68 ENST00000490686.1
immunoglobulin kappa variable 1-17
chr22_+_22357739 18.62 ENST00000390294.2
immunoglobulin lambda variable 1-47
chr2_-_89297785 18.32 ENST00000465170.1
immunoglobulin kappa variable 1-37 (non-functional)
chr22_+_22594528 17.23 ENST00000390303.3
immunoglobulin lambda variable 3-32 (non-functional)
chr22_+_22686724 17.15 ENST00000390305.2
immunoglobulin lambda variable 3-25
chr2_+_90038848 16.79 ENST00000390270.2
immunoglobulin kappa variable 3D-20
chr19_+_49335396 16.26 ENST00000598095.5
ENST00000426897.6
ENST00000323906.9
ENST00000535669.6
ENST00000597602.1
ENST00000595660.1
CD37 molecule
chr2_+_89862438 15.72 ENST00000448155.2
immunoglobulin kappa variable 1D-39
chr11_+_1870150 15.68 ENST00000429923.5
ENST00000418975.1
ENST00000406638.6
lymphocyte specific protein 1
chr2_-_88947820 15.38 ENST00000496168.1
immunoglobulin kappa variable 1-5
chr11_+_1870252 14.92 ENST00000612798.4
lymphocyte specific protein 1
chr2_-_88966767 14.86 ENST00000464162.1
immunoglobulin kappa variable 1-6
chr2_-_89268506 14.80 ENST00000473726.1
immunoglobulin kappa variable 1-33
chr2_+_90154073 14.30 ENST00000611391.1
immunoglobulin kappa variable 1D-13
chr15_+_88639009 14.29 ENST00000306072.10
interferon stimulated exonuclease gene 20
chr22_+_22327298 13.81 ENST00000390291.2
immunoglobulin lambda variable 1-50 (non-functional)
chr15_+_88638947 13.75 ENST00000559876.2
interferon stimulated exonuclease gene 20
chr22_+_22588155 13.73 ENST00000390302.3
immunoglobulin lambda variable 2-33 (non-functional)
chr22_+_22380766 13.32 ENST00000390297.3
immunoglobulin lambda variable 1-44
chr15_-_22160868 12.68 ENST00000604066.1
immunoglobulin heavy variable 1/OR15-1 (non-functional)
chr19_-_45322867 12.16 ENST00000221476.4
creatine kinase, M-type
chr17_-_35880350 12.12 ENST00000605140.6
ENST00000651122.1
ENST00000603197.6
C-C motif chemokine ligand 5
chr12_+_111766887 12.04 ENST00000416293.7
ENST00000261733.7
aldehyde dehydrogenase 2 family member
chr22_+_22322452 11.71 ENST00000390290.3
immunoglobulin lambda variable 1-51
chr14_-_94390650 11.67 ENST00000449399.7
ENST00000404814.8
serpin family A member 1
chr5_-_140633167 11.64 ENST00000302014.11
CD14 molecule
chr19_-_10334723 11.59 ENST00000592945.1
intercellular adhesion molecule 3
chr14_-_106269133 11.57 ENST00000390609.3
immunoglobulin heavy variable 3-23
chrX_-_107775951 11.39 ENST00000315660.8
ENST00000372384.6
ENST00000502650.1
ENST00000506724.1
TSC22 domain family member 3
chr16_+_30183595 11.28 ENST00000219150.10
ENST00000570045.5
ENST00000565497.5
ENST00000570244.5
coronin 1A
chr14_-_106762576 11.26 ENST00000624687.1
immunoglobulin heavy variable 1-69D
chr11_+_47248885 11.19 ENST00000395397.7
ENST00000405576.5
nuclear receptor subfamily 1 group H member 3
chr11_+_47248924 10.72 ENST00000481889.6
ENST00000436778.5
ENST00000531660.5
ENST00000407404.5
nuclear receptor subfamily 1 group H member 3
chr14_-_94390614 10.72 ENST00000553327.5
ENST00000556955.5
ENST00000557118.5
ENST00000440909.5
serpin family A member 1
chr14_-_94390667 10.62 ENST00000557492.5
ENST00000355814.8
ENST00000437397.5
ENST00000448921.5
ENST00000393088.8
serpin family A member 1
chr9_+_136980211 9.69 ENST00000444903.2
prostaglandin D2 synthase
chr14_-_106639589 9.41 ENST00000390630.3
immunoglobulin heavy variable 4-61
chr19_+_18173804 9.41 ENST00000407280.4
IFI30 lysosomal thiol reductase
chr4_+_674559 9.31 ENST00000511290.5
myosin light chain 5
chr19_-_6720641 9.07 ENST00000245907.11
complement C3
chr5_-_42825884 8.76 ENST00000506577.5
selenoprotein P
chr22_+_22409755 8.65 ENST00000390299.2
immunoglobulin lambda variable 1-40
chr1_+_209675404 8.60 ENST00000367029.5
G0/G1 switch 2
chr12_-_14567714 8.59 ENST00000240617.10
phospholipase B domain containing 1
chr13_-_46390042 8.42 ENST00000389908.7
rubicon like autophagy enhancer
chr3_+_48446710 8.39 ENST00000635099.1
ENST00000346691.9
ENST00000320211.10
ATR interacting protein
chr19_-_13102848 7.92 ENST00000264824.5
LYL1 basic helix-loop-helix family member
chr17_-_81911350 7.87 ENST00000570388.5
phosphate cytidylyltransferase 2, ethanolamine
chr3_+_186930759 7.83 ENST00000677292.1
ENST00000458216.5
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr10_+_86968432 7.83 ENST00000416348.1
ENST00000372013.8
adipogenesis regulatory factor
chr3_+_46979659 7.75 ENST00000450053.8
neurobeachin like 2
chr10_+_112376193 7.51 ENST00000433418.6
ENST00000356116.6
ENST00000354273.5
acyl-CoA synthetase long chain family member 5
chr11_-_47248835 7.49 ENST00000673604.1
ENST00000256997.9
acid phosphatase 2, lysosomal
chr19_+_58278948 7.42 ENST00000621650.2
ENST00000591325.1
zinc finger protein 8
ZNF8-ERVK3-1 readthrough
chr11_-_615570 7.32 ENST00000649187.1
ENST00000647801.1
ENST00000397566.5
ENST00000397570.5
interferon regulatory factor 7
chr9_+_121207774 7.06 ENST00000373823.7
gelsolin
chr19_+_7903843 7.03 ENST00000397981.7
ENST00000397979.4
ENST00000397983.7
mitogen-activated protein kinase kinase 7
chr2_-_159904668 6.73 ENST00000504764.5
ENST00000505052.1
ENST00000263636.5
LY75-CD302 readthrough
lymphocyte antigen 75
chr2_-_219245389 6.71 ENST00000428427.1
ENST00000432839.1
ENST00000295759.12
ENST00000424620.1
galactosidase beta 1 like
chr1_-_111427731 6.70 ENST00000369732.4
oviductal glycoprotein 1
chr11_-_47248789 6.65 ENST00000529444.7
ENST00000672787.1
ENST00000672073.1
ENST00000672636.2
ENST00000527256.7
acid phosphatase 2, lysosomal
chr12_-_123972709 6.46 ENST00000545891.5
coiled-coil domain containing 92
chr22_-_50578003 6.40 ENST00000405237.7
carnitine palmitoyltransferase 1B
chrX_-_107716401 6.39 ENST00000486554.1
ENST00000372390.8
TSC22 domain family member 3
chr1_+_27234612 6.38 ENST00000319394.8
ENST00000361771.7
WD and tetratricopeptide repeats 1
chr16_+_1240698 6.31 ENST00000561736.2
ENST00000338844.8
ENST00000461509.6
tryptase alpha/beta 1
chr3_-_52454032 6.27 ENST00000232975.8
troponin C1, slow skeletal and cardiac type
chr3_+_186930518 6.25 ENST00000169298.8
ENST00000457772.6
ENST00000455441.5
ENST00000427315.5
ST6 beta-galactoside alpha-2,6-sialyltransferase 1
chr6_-_41735557 6.11 ENST00000373033.6
transcription factor EB
chr16_-_28609992 6.09 ENST00000314752.11
sulfotransferase family 1A member 1
chr2_+_11539833 5.87 ENST00000263834.9
growth regulating estrogen receptor binding 1
chr6_+_31615215 5.84 ENST00000337917.11
ENST00000376059.8
allograft inflammatory factor 1
chr5_+_134905100 5.83 ENST00000512783.5
ENST00000254908.11
pterin-4 alpha-carbinolamine dehydratase 2
chrY_-_1452882 5.77 ENST00000381317.9_PAR_Y
ENST00000381333.9_PAR_Y
acetylserotonin O-methyltransferase like
chr1_-_23825402 5.75 ENST00000235958.4
ENST00000436439.6
ENST00000374490.8
3-hydroxy-3-methylglutaryl-CoA lyase
chr14_+_94110728 5.66 ENST00000616764.4
ENST00000618863.1
ENST00000611954.4
ENST00000618200.4
ENST00000621160.4
ENST00000555819.5
ENST00000620396.4
ENST00000612813.4
ENST00000620066.1
interferon alpha inducible protein 27
chr17_-_81911367 5.65 ENST00000538936.7
ENST00000538721.6
ENST00000573636.6
ENST00000571105.5
ENST00000576343.5
ENST00000572473.1
phosphate cytidylyltransferase 2, ethanolamine
chr6_-_41736239 5.64 ENST00000358871.6
transcription factor EB
chr17_+_36064265 5.63 ENST00000616054.2
C-C motif chemokine ligand 18
chr22_-_50577915 5.62 ENST00000360719.6
ENST00000457250.5
carnitine palmitoyltransferase 1B
chr20_+_3820515 5.59 ENST00000246041.6
ENST00000379573.6
ENST00000379567.6
ENST00000455742.5
ENST00000615891.2
adaptor related protein complex 5 subunit sigma 1
chr7_+_30028644 5.53 ENST00000440706.3
pleckstrin homology domain containing A8
chr2_+_230225718 5.53 ENST00000420434.7
ENST00000392045.8
ENST00000417495.7
ENST00000343805.10
SP140 nuclear body protein
chr11_-_615921 5.50 ENST00000348655.11
ENST00000525445.6
ENST00000330243.9
interferon regulatory factor 7
chr11_-_60952559 5.43 ENST00000538739.2
solute carrier family 15 member 3
chr6_-_49744434 5.36 ENST00000433368.6
ENST00000354620.4
cysteine rich secretory protein 3
chr17_-_81911200 5.32 ENST00000570391.5
phosphate cytidylyltransferase 2, ethanolamine
chr22_-_38755458 5.29 ENST00000405510.5
ENST00000433561.5
Sad1 and UNC84 domain containing 2
chr11_+_62419025 5.27 ENST00000278282.3
secretoglobin family 1A member 1
chr17_-_41521719 5.10 ENST00000393976.6
keratin 15
chr20_+_49812697 5.05 ENST00000417961.5
solute carrier family 9 member A8
chr10_+_74826550 5.04 ENST00000649657.1
ENST00000372714.6
ENST00000649442.1
ENST00000648539.1
ENST00000647666.1
ENST00000648048.1
ENST00000287239.10
ENST00000649375.1
lysine acetyltransferase 6B
chr11_-_72752376 5.00 ENST00000393609.8
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr11_-_60952134 4.97 ENST00000679573.1
ENST00000681882.1
ENST00000681951.1
ENST00000227880.8
solute carrier family 15 member 3
chr15_+_28885955 4.95 ENST00000558402.5
ENST00000683413.1
ENST00000558330.5
amyloid beta precursor protein binding family A member 2
chr8_-_69833338 4.90 ENST00000524945.5
solute carrier organic anion transporter family member 5A1
chr22_-_23754376 4.88 ENST00000398465.3
ENST00000248948.4
V-set pre-B cell surrogate light chain 3
chr16_-_1230089 4.86 ENST00000612142.1
ENST00000606293.5
tryptase beta 2
chr1_+_19664859 4.86 ENST00000289753.2
5-hydroxytryptamine receptor 6
chr1_+_19596960 4.85 ENST00000617872.4
ENST00000322753.7
ENST00000602662.1
mitochondrial contact site and cristae organizing system subunit 10
NBL1, DAN family BMP antagonist
chrY_+_20575716 4.81 ENST00000361365.7
eukaryotic translation initiation factor 1A Y-linked
chr11_+_43358908 4.77 ENST00000039989.9
ENST00000299240.10
tetratricopeptide repeat domain 17
chr20_+_49812818 4.75 ENST00000361573.3
solute carrier family 9 member A8
chr7_-_102543849 4.75 ENST00000644544.1
uroplakin 3B like 2
chr11_-_60952067 4.69 ENST00000681275.1
solute carrier family 15 member 3
chr16_+_590200 4.68 ENST00000563109.1
RAB40C, member RAS oncogene family
chr22_-_23580223 4.68 ENST00000249053.3
ENST00000330377.3
ENST00000438703.1
immunoglobulin lambda like polypeptide 1
chr3_-_15427497 4.62 ENST00000443029.5
ENST00000383789.9
ENST00000450816.6
ENST00000383790.8
methyltransferase like 6
chr6_-_2903300 4.60 ENST00000380698.5
serpin family B member 9
chr6_+_35297809 4.60 ENST00000316637.7
DEF6 guanine nucleotide exchange factor
chr12_-_13103637 4.58 ENST00000545401.5
ENST00000432710.6
ENST00000351606.10
ENST00000651961.1
ENST00000542415.5
germ cell associated 1
chr6_-_90296824 4.56 ENST00000257749.9
BTB domain and CNC homolog 2
chr19_+_35268921 4.56 ENST00000222305.8
ENST00000343550.9
upstream transcription factor 2, c-fos interacting
chr15_+_81196871 4.55 ENST00000559383.5
ENST00000394660.6
ENST00000683961.1
interleukin 16
chr1_+_9651723 4.55 ENST00000377346.9
ENST00000536656.5
ENST00000628140.2
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
chr1_+_220786853 4.54 ENST00000366910.10
mitochondrial amidoxime reducing component 1
chr19_+_35533436 4.53 ENST00000222286.9
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr19_+_35269065 4.50 ENST00000595068.5
ENST00000379134.7
ENST00000594064.5
ENST00000598058.1
upstream transcription factor 2, c-fos interacting
chr19_-_15331890 4.50 ENST00000594841.5
ENST00000601941.1
bromodomain containing 4
chr2_-_230225628 4.43 ENST00000540870.5
SP110 nuclear body protein
chr15_-_72783685 4.41 ENST00000456471.3
ENST00000311669.12
ADP dependent glucokinase
chr11_+_8682782 4.38 ENST00000531978.5
ENST00000524496.5
ENST00000532359.5
ENST00000314138.11
ENST00000530022.5
ribosomal protein L27a
chr5_-_154850570 4.37 ENST00000326080.10
ENST00000519501.5
ENST00000518651.5
ENST00000517938.5
ENST00000520461.1
fatty acid hydroxylase domain containing 2
chr6_+_29827817 4.36 ENST00000360323.11
ENST00000376818.7
ENST00000376815.3
major histocompatibility complex, class I, G
chr9_-_33264559 4.35 ENST00000473781.1
ENST00000379704.7
ENST00000488499.1
BAG cochaperone 1
chr19_+_2389761 4.30 ENST00000648592.1
transmembrane serine protease 9
chr14_-_106360320 4.30 ENST00000390615.2
immunoglobulin heavy variable 3-33
chr3_+_15427551 4.29 ENST00000396842.7
ELL associated factor 1
chr9_-_136205122 4.27 ENST00000371748.10
LIM homeobox 3
chr20_+_63981117 4.24 ENST00000266079.5
pre-mRNA processing factor 6
chr16_+_85027735 4.21 ENST00000258180.7
ENST00000538274.5
KIAA0513
chr14_-_106005574 4.21 ENST00000390595.3
immunoglobulin heavy variable 1-3
chr1_+_205227889 4.20 ENST00000358024.8
transmembrane and coiled-coil domain family 2
chrY_+_20575792 4.20 ENST00000382772.3
eukaryotic translation initiation factor 1A Y-linked
chr16_+_19718264 4.17 ENST00000564186.5
IQ motif containing K
chr6_-_73452124 4.17 ENST00000680833.1
cyclic GMP-AMP synthase
chr22_+_22195753 4.16 ENST00000390285.4
immunoglobulin lambda variable 6-57
chr17_-_36388423 4.13 ENST00000610350.3
TBC1 domain family member 3H
chr22_-_36817001 4.13 ENST00000406910.6
ENST00000417718.7
parvalbumin
chr8_+_11494367 4.12 ENST00000259089.9
ENST00000529894.1
BLK proto-oncogene, Src family tyrosine kinase
chr14_+_103529208 4.11 ENST00000299202.4
tRNA methyltransferase 61A
chr16_+_10386049 4.11 ENST00000562527.5
ENST00000396559.5
ENST00000396560.6
ENST00000562102.5
ENST00000543967.5
ENST00000569939.5
ENST00000569900.5
activating transcription factor 7 interacting protein 2
chr15_+_69452811 4.10 ENST00000357790.5
ENST00000260379.11
ENST00000560274.1
ribosomal protein lateral stalk subunit P1
chr16_-_1826778 4.09 ENST00000569339.1
ENST00000397356.8
ENST00000455446.6
ENST00000397353.6
hydroxyacylglutathione hydrolase
chr19_-_11529116 4.08 ENST00000592312.5
ENST00000590480.1
ENST00000585318.5
ENST00000270517.12
ENST00000252440.11
ENST00000417981.6
ECSIT signaling integrator
chr19_-_51009586 4.08 ENST00000594211.2
kallikrein related peptidase 9
chr22_-_42720813 4.06 ENST00000381278.4
alpha 1,4-galactosyltransferase (P blood group)
chr1_+_153776596 4.03 ENST00000458027.5
solute carrier family 27 member 3
chr19_-_4455292 4.03 ENST00000394765.7
ENST00000592515.1
UBX domain protein 6
chr6_-_49744378 4.03 ENST00000371159.8
ENST00000263045.9
cysteine rich secretory protein 3
chr12_-_123972824 4.02 ENST00000238156.8
ENST00000545037.1
coiled-coil domain containing 92
chr11_-_35419542 4.00 ENST00000643305.1
ENST00000644351.1
ENST00000278379.9
ENST00000644779.1
solute carrier family 1 member 2
chr21_+_39445824 3.94 ENST00000380637.7
ENST00000380634.5
ENST00000458295.5
ENST00000440288.6
ENST00000380631.5
SH3 domain binding glutamate rich protein
chr1_+_12166978 3.93 ENST00000376259.7
ENST00000536782.2
TNF receptor superfamily member 1B
chr12_+_113221429 3.93 ENST00000551096.5
ENST00000551099.5
ENST00000552897.5
ENST00000550785.5
ENST00000549279.1
ENST00000335509.11
two pore segment channel 1
chr2_+_118942188 3.93 ENST00000327097.5
macrophage receptor with collagenous structure
chr5_-_150086511 3.92 ENST00000675795.1
colony stimulating factor 1 receptor
chr3_-_184017863 3.91 ENST00000427120.6
ENST00000334444.11
ENST00000392579.6
ENST00000382494.6
ENST00000265586.10
ENST00000446941.2
ATP binding cassette subfamily C member 5
chr11_+_8683201 3.89 ENST00000526562.5
ENST00000525981.1
ribosomal protein L27a
chr22_+_37639660 3.87 ENST00000649765.2
ENST00000451997.6
SH3 domain binding protein 1
novel protein
chr1_+_244969976 3.87 ENST00000366522.6
EF-hand calcium binding domain 2
chr1_+_54641806 3.86 ENST00000409996.5
maestro heat like repeat family member 7
chr16_+_85027761 3.79 ENST00000683363.1
KIAA0513
chr17_-_38192555 3.79 ENST00000620215.3
TBC1 domain family member 3
chr17_-_36439566 3.77 ENST00000620210.1
TBC1 domain family member 3F
chr17_+_38003976 3.76 ENST00000616101.4
TBC1 domain family member 3D
chr1_-_155188351 3.69 ENST00000462317.5
mucin 1, cell surface associated
chr1_-_226737277 3.67 ENST00000272117.7
inositol-trisphosphate 3-kinase B
chr16_+_29459913 3.66 ENST00000360423.12
sulfotransferase family 1A member 4
chr8_+_102551583 3.63 ENST00000285402.4
outer dense fiber of sperm tails 1
chr17_+_37924415 3.62 ENST00000620247.1
TBC1 domain family member 3K
chr19_-_913182 3.62 ENST00000361574.10
ENST00000587975.2
R3H domain containing 4
chr3_-_14178569 3.61 ENST00000285021.12
XPC complex subunit, DNA damage recognition and repair factor
chr3_+_88059231 3.60 ENST00000636215.2
zinc finger protein 654
chr17_-_37989048 3.59 ENST00000617678.2
ENST00000612727.5
TBC1 domain family member 3L
chr5_+_40679907 3.59 ENST00000302472.4
prostaglandin E receptor 4
chr5_-_132011794 3.58 ENST00000650697.1
acyl-CoA synthetase long chain family member 6
chr1_+_54641754 3.57 ENST00000339553.9
ENST00000421030.7
maestro heat like repeat family member 7
chr17_+_38127951 3.55 ENST00000621587.2
TBC1 domain family member 3E
chr10_-_98446878 3.54 ENST00000338546.9
ENST00000325103.10
ENST00000361490.9
HPS1 biogenesis of lysosomal organelles complex 3 subunit 1
chr17_+_36323884 3.54 ENST00000569055.2
TBC1 domain family member 3G
chr11_+_65639860 3.54 ENST00000527525.5
signal-induced proliferation-associated 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
9.3 28.0 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
7.3 21.9 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
4.8 43.3 GO:0060267 positive regulation of respiratory burst(GO:0060267)
4.7 18.8 GO:1902732 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229) positive regulation of chondrocyte proliferation(GO:1902732)
3.7 22.4 GO:2000110 negative regulation of macrophage apoptotic process(GO:2000110)
3.0 9.1 GO:0002445 type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892)
2.7 393.4 GO:0006958 complement activation, classical pathway(GO:0006958)
2.3 11.6 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
2.3 9.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) late viral transcription(GO:0019086)
2.2 6.7 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
2.2 17.8 GO:0070236 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
2.1 6.3 GO:0002086 diaphragm contraction(GO:0002086)
1.9 11.3 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
1.7 6.8 GO:1903627 regulation of calcium-dependent ATPase activity(GO:1903610) negative regulation of calcium-dependent ATPase activity(GO:1903611) regulation of dUTP diphosphatase activity(GO:1903627) positive regulation of dUTP diphosphatase activity(GO:1903629) negative regulation of aminoacyl-tRNA ligase activity(GO:1903631) regulation of leucine-tRNA ligase activity(GO:1903633) negative regulation of leucine-tRNA ligase activity(GO:1903634)
1.7 5.1 GO:0070843 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
1.7 8.3 GO:2000870 oocyte growth(GO:0001555) regulation of progesterone secretion(GO:2000870)
1.5 4.6 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
1.4 7.1 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
1.4 5.5 GO:0035627 ceramide transport(GO:0035627)
1.3 5.0 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
1.2 4.8 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
1.2 6.0 GO:0030309 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
1.2 3.6 GO:2000417 negative regulation of eosinophil migration(GO:2000417)
1.2 5.9 GO:0001575 globoside metabolic process(GO:0001575)
1.2 8.2 GO:0033029 regulation of neutrophil apoptotic process(GO:0033029)
1.2 5.8 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
1.1 2.3 GO:0002461 tolerance induction dependent upon immune response(GO:0002461)
1.1 2.2 GO:0002331 pre-B cell differentiation(GO:0002329) pre-B cell allelic exclusion(GO:0002331)
1.1 3.3 GO:0038178 complement component C5a signaling pathway(GO:0038178)
1.1 21.0 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
1.1 8.8 GO:0001887 selenium compound metabolic process(GO:0001887)
1.1 5.3 GO:0031022 nuclear migration along microfilament(GO:0031022)
1.1 5.3 GO:0010193 response to ozone(GO:0010193)
1.0 23.7 GO:0006068 ethanol catabolic process(GO:0006068)
1.0 4.1 GO:0009438 methylglyoxal metabolic process(GO:0009438)
1.0 3.0 GO:0061760 antifungal innate immune response(GO:0061760)
1.0 7.8 GO:0072719 cellular response to cisplatin(GO:0072719)
1.0 169.4 GO:0002377 immunoglobulin production(GO:0002377)
0.9 2.8 GO:0032761 negative regulation of T cell tolerance induction(GO:0002665) negative regulation of T cell anergy(GO:0002668) negative regulation of lymphocyte anergy(GO:0002912) regulation of lymphotoxin A production(GO:0032681) positive regulation of lymphotoxin A production(GO:0032761) regulation of lymphotoxin A biosynthetic process(GO:0043016) positive regulation of lymphotoxin A biosynthetic process(GO:0043017)
0.9 7.5 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.9 5.4 GO:0016554 cytidine to uridine editing(GO:0016554)
0.9 3.5 GO:0042631 cellular response to water deprivation(GO:0042631)
0.9 15.9 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.9 4.4 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.9 3.5 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
0.9 2.6 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.9 2.6 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199) response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.8 3.4 GO:0021759 globus pallidus development(GO:0021759)
0.8 3.4 GO:0018879 biphenyl metabolic process(GO:0018879)
0.8 12.2 GO:0006600 creatine metabolic process(GO:0006600)
0.8 7.0 GO:0035897 proteolysis in other organism(GO:0035897)
0.8 10.8 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.8 3.8 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.7 3.0 GO:0046968 peptide antigen transport(GO:0046968)
0.7 5.8 GO:0046146 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.7 2.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.7 4.3 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.7 2.8 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.7 2.1 GO:0002384 hepatic immune response(GO:0002384)
0.7 2.7 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.7 2.0 GO:0019046 release from viral latency(GO:0019046)
0.7 7.9 GO:0001955 blood vessel maturation(GO:0001955)
0.6 7.1 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.6 3.2 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
0.6 2.4 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.6 1.8 GO:0010587 miRNA catabolic process(GO:0010587)
0.6 3.5 GO:1903232 melanosome assembly(GO:1903232)
0.6 3.5 GO:0034127 regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034127)
0.6 6.4 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.6 1.7 GO:0051684 maintenance of Golgi location(GO:0051684)
0.5 1.6 GO:0001757 somite specification(GO:0001757) sclerotome development(GO:0061056)
0.5 9.2 GO:0036149 phosphatidylinositol acyl-chain remodeling(GO:0036149)
0.5 2.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.5 3.2 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.5 3.1 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.5 2.0 GO:0009440 cyanate metabolic process(GO:0009439) cyanate catabolic process(GO:0009440)
0.5 1.5 GO:1903626 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.5 9.7 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.5 32.9 GO:0006953 acute-phase response(GO:0006953)
0.5 4.3 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.5 1.9 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.5 1.4 GO:0071462 cellular response to water stimulus(GO:0071462) cellular response to hydrostatic pressure(GO:0071464)
0.5 1.4 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.4 2.7 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.4 2.2 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.4 3.9 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.4 15.6 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.4 1.7 GO:0071110 protein biotinylation(GO:0009305) histone biotinylation(GO:0071110)
0.4 1.3 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.4 1.3 GO:0009080 alanine metabolic process(GO:0006522) alanine catabolic process(GO:0006524) pyruvate family amino acid metabolic process(GO:0009078) pyruvate family amino acid catabolic process(GO:0009080)
0.4 2.1 GO:1901091 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.4 6.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.4 38.6 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.4 4.5 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.4 1.6 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.4 2.0 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.4 4.0 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.4 3.9 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.4 1.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.4 3.0 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.4 1.1 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.4 1.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.4 8.5 GO:0030488 tRNA methylation(GO:0030488)
0.4 1.5 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) histone H3-K36 dimethylation(GO:0097676)
0.4 8.0 GO:0006853 carnitine shuttle(GO:0006853)
0.4 5.8 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.4 2.5 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.4 1.8 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.4 15.5 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.4 30.2 GO:0006968 cellular defense response(GO:0006968)
0.3 3.1 GO:0051026 chiasma assembly(GO:0051026)
0.3 1.4 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.3 3.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.3 3.1 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888) fat pad development(GO:0060613) positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255) positive regulation of protein monoubiquitination(GO:1902527)
0.3 1.7 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.3 2.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.3 3.1 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.3 2.2 GO:0050666 regulation of sulfur amino acid metabolic process(GO:0031335) regulation of homocysteine metabolic process(GO:0050666)
0.3 3.4 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.3 3.0 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.3 1.2 GO:0071918 urea transmembrane transport(GO:0071918)
0.3 2.4 GO:0051414 response to cortisol(GO:0051414)
0.3 0.9 GO:0051673 membrane disruption in other organism(GO:0051673)
0.3 0.9 GO:0035634 response to stilbenoid(GO:0035634)
0.3 3.2 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.3 92.1 GO:0002250 adaptive immune response(GO:0002250)
0.3 2.8 GO:0021633 optic nerve structural organization(GO:0021633)
0.3 2.2 GO:0015886 heme transport(GO:0015886)
0.3 3.6 GO:0070914 UV-damage excision repair(GO:0070914)
0.3 7.8 GO:0030220 platelet formation(GO:0030220)
0.3 1.4 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.3 4.0 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.3 2.3 GO:0072592 oxygen metabolic process(GO:0072592)
0.2 2.0 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.2 3.2 GO:0042355 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.2 3.7 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.2 3.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 1.7 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 0.7 GO:0036233 glycine import(GO:0036233)
0.2 2.9 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.2 2.9 GO:0071415 cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.2 3.0 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.2 2.9 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.2 0.7 GO:0015722 canalicular bile acid transport(GO:0015722)
0.2 1.5 GO:0035815 positive regulation of renal sodium excretion(GO:0035815)
0.2 4.6 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.2 1.5 GO:0023041 neuronal signal transduction(GO:0023041)
0.2 1.1 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.2 0.6 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.2 1.9 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 1.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.2 3.0 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 4.1 GO:0050855 regulation of B cell receptor signaling pathway(GO:0050855)
0.2 1.8 GO:0045792 negative regulation of cell size(GO:0045792)
0.2 1.0 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.2 4.5 GO:0045821 positive regulation of glycolytic process(GO:0045821)
0.2 1.5 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.2 0.4 GO:0043032 positive regulation of macrophage activation(GO:0043032)
0.2 1.5 GO:0045780 positive regulation of alkaline phosphatase activity(GO:0010694) positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.2 1.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 1.1 GO:1900107 embryonic hindgut morphogenesis(GO:0048619) regulation of nodal signaling pathway(GO:1900107)
0.2 4.6 GO:0007616 long-term memory(GO:0007616)
0.2 2.9 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.2 0.5 GO:0048148 behavioral response to cocaine(GO:0048148)
0.2 1.9 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.2 1.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.2 2.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2 1.2 GO:0006477 protein sulfation(GO:0006477) heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2 1.7 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.2 7.5 GO:0036297 interstrand cross-link repair(GO:0036297)
0.2 1.4 GO:0098535 de novo centriole assembly(GO:0098535)
0.1 1.0 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.4 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.1 1.4 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.1 3.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 1.4 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.1 3.9 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.1 4.5 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 0.6 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.1 1.9 GO:0006491 N-glycan processing(GO:0006491)
0.1 2.1 GO:0015884 folic acid transport(GO:0015884)
0.1 2.0 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 1.1 GO:0036507 protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) endoplasmic reticulum mannose trimming(GO:1904380)
0.1 1.9 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 1.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.1 0.5 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.1 0.3 GO:0009386 translational attenuation(GO:0009386)
0.1 2.1 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.1 3.8 GO:0043277 apoptotic cell clearance(GO:0043277)
0.1 0.4 GO:0021539 subthalamus development(GO:0021539)
0.1 2.7 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 1.9 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.1 1.5 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 1.3 GO:0090344 negative regulation of cell aging(GO:0090344)
0.1 0.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.1 1.8 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 2.4 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 0.3 GO:0034444 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) response to fluoride(GO:1902617)
0.1 2.4 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.1 4.7 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.1 4.3 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 1.1 GO:0015074 DNA integration(GO:0015074)
0.1 0.3 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.1 10.3 GO:0070268 cornification(GO:0070268)
0.1 1.3 GO:0060033 anatomical structure regression(GO:0060033)
0.1 2.7 GO:0015695 organic cation transport(GO:0015695)
0.1 4.9 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.1 3.3 GO:0032570 response to progesterone(GO:0032570)
0.1 2.7 GO:0060037 pharyngeal system development(GO:0060037)
0.1 2.9 GO:0031055 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 1.6 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.1 1.1 GO:0042711 maternal behavior(GO:0042711) parental behavior(GO:0060746)
0.1 1.8 GO:0019835 cytolysis(GO:0019835)
0.1 4.5 GO:0051341 regulation of oxidoreductase activity(GO:0051341)
0.1 0.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 5.9 GO:0006334 nucleosome assembly(GO:0006334)
0.1 3.7 GO:0006584 catecholamine metabolic process(GO:0006584) catechol-containing compound metabolic process(GO:0009712)
0.1 0.7 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1 0.6 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.1 1.9 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 2.1 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 2.3 GO:0010165 response to X-ray(GO:0010165)
0.1 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 1.1 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.6 GO:0038171 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 2.1 GO:0008333 endosome to lysosome transport(GO:0008333)
0.1 0.1 GO:0010159 specification of organ position(GO:0010159)
0.1 7.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.6 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 1.2 GO:0006525 arginine metabolic process(GO:0006525)
0.1 1.7 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.1 2.0 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.1 0.4 GO:0070995 NADPH oxidation(GO:0070995)
0.1 11.6 GO:0006909 phagocytosis(GO:0006909)
0.1 6.3 GO:0007286 spermatid development(GO:0007286)
0.1 4.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 2.3 GO:0009395 phospholipid catabolic process(GO:0009395)
0.1 3.5 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 4.0 GO:0042255 ribosome assembly(GO:0042255)
0.0 1.9 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.2 GO:0038042 dimeric G-protein coupled receptor signaling pathway(GO:0038042) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 3.5 GO:0000724 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 3.1 GO:0009798 axis specification(GO:0009798)
0.0 2.1 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 3.0 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.0 1.1 GO:0009083 branched-chain amino acid metabolic process(GO:0009081) branched-chain amino acid catabolic process(GO:0009083)
0.0 4.8 GO:0060333 interferon-gamma-mediated signaling pathway(GO:0060333)
0.0 4.8 GO:0044782 cilium organization(GO:0044782)
0.0 0.8 GO:0042730 fibrinolysis(GO:0042730)
0.0 1.0 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 1.3 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 1.4 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 2.7 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 1.5 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.0 0.1 GO:0021590 hindbrain maturation(GO:0021578) cerebellum maturation(GO:0021590) central nervous system maturation(GO:0021626) cerebellar cortex maturation(GO:0021699)
0.0 1.4 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 1.5 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.0 2.5 GO:0006368 transcription elongation from RNA polymerase II promoter(GO:0006368)
0.0 0.4 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.6 GO:0060384 innervation(GO:0060384)
0.0 0.5 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.7 GO:0003407 neural retina development(GO:0003407)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.4 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.7 GO:0071347 cellular response to interleukin-1(GO:0071347)
0.0 0.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
14.4 43.2 GO:0071750 dimeric IgA immunoglobulin complex(GO:0071750) secretory dimeric IgA immunoglobulin complex(GO:0071752)
3.1 18.8 GO:0097013 phagocytic vesicle lumen(GO:0097013)
2.5 7.4 GO:0031515 tRNA (m1A) methyltransferase complex(GO:0031515)
2.2 6.7 GO:0030312 external encapsulating structure(GO:0030312)
1.7 83.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
1.3 5.4 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
1.3 11.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
1.2 3.5 GO:0031085 BLOC-3 complex(GO:0031085)
1.0 6.3 GO:1990584 cardiac Troponin complex(GO:1990584)
0.9 169.4 GO:0072562 blood microparticle(GO:0072562)
0.7 11.8 GO:0031089 platelet dense granule lumen(GO:0031089)
0.7 17.1 GO:0001891 phagocytic cup(GO:0001891)
0.7 3.9 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.6 3.1 GO:0005713 recombination nodule(GO:0005713)
0.6 3.9 GO:0043196 varicosity(GO:0043196)
0.6 4.4 GO:0030891 VCB complex(GO:0030891) Cul5-RING ubiquitin ligase complex(GO:0031466)
0.5 2.7 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.5 4.3 GO:0044327 dendritic spine head(GO:0044327)
0.5 2.8 GO:0005577 fibrinogen complex(GO:0005577)
0.5 5.0 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.5 1.4 GO:0098536 deuterosome(GO:0098536)
0.4 1.3 GO:0005927 muscle tendon junction(GO:0005927)
0.4 2.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.4 5.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.4 3.6 GO:0001520 outer dense fiber(GO:0001520)
0.4 4.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.4 2.3 GO:0014802 terminal cisterna(GO:0014802)
0.4 30.6 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.3 5.8 GO:0097440 apical dendrite(GO:0097440)
0.3 2.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.3 4.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.3 1.5 GO:0032044 DSIF complex(GO:0032044)
0.3 1.4 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.3 11.3 GO:0005859 muscle myosin complex(GO:0005859)
0.3 1.9 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.3 1.9 GO:0033391 chromatoid body(GO:0033391)
0.3 7.2 GO:0005682 U5 snRNP(GO:0005682)
0.3 1.8 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.3 11.8 GO:0030673 axolemma(GO:0030673)
0.3 1.0 GO:0071546 pi-body(GO:0071546)
0.3 18.0 GO:0015030 Cajal body(GO:0015030)
0.2 3.4 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.2 2.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.2 1.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2 14.9 GO:0001772 immunological synapse(GO:0001772)
0.2 19.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.2 1.7 GO:0030897 HOPS complex(GO:0030897)
0.2 1.4 GO:0031088 platelet dense granule membrane(GO:0031088) platelet dense granule(GO:0042827)
0.2 2.8 GO:0033010 paranodal junction(GO:0033010)
0.2 6.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.2 1.5 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2 3.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.2 8.2 GO:0016235 aggresome(GO:0016235)
0.2 27.0 GO:0043202 lysosomal lumen(GO:0043202)
0.2 0.5 GO:0032426 stereocilium tip(GO:0032426)
0.2 10.3 GO:1904724 tertiary granule lumen(GO:1904724)
0.2 4.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 0.5 GO:0036284 tubulobulbar complex(GO:0036284)
0.2 229.3 GO:0005615 extracellular space(GO:0005615)
0.1 1.6 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 2.9 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 1.2 GO:0005827 polar microtubule(GO:0005827)
0.1 0.4 GO:0002079 inner acrosomal membrane(GO:0002079)
0.1 2.0 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.1 2.5 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 3.3 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.6 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.1 3.5 GO:0071565 nBAF complex(GO:0071565)
0.1 0.8 GO:0005594 collagen type IX trimer(GO:0005594)
0.1 3.9 GO:0005581 collagen trimer(GO:0005581)
0.1 6.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 4.8 GO:0016592 mediator complex(GO:0016592)
0.1 10.9 GO:0070821 tertiary granule membrane(GO:0070821)
0.1 0.5 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 1.7 GO:0000242 pericentriolar material(GO:0000242)
0.1 3.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.6 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 2.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 5.2 GO:0016459 myosin complex(GO:0016459)
0.1 1.0 GO:0097427 microtubule bundle(GO:0097427)
0.1 3.9 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.7 GO:0005652 nuclear lamina(GO:0005652)
0.1 1.0 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.6 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.8 GO:0070852 cell body fiber(GO:0070852)
0.1 7.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 7.3 GO:0005814 centriole(GO:0005814)
0.1 2.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 12.2 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 1.5 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.1 2.1 GO:0001533 cornified envelope(GO:0001533)
0.1 0.8 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 3.3 GO:0000428 DNA-directed RNA polymerase complex(GO:0000428)
0.0 0.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 2.5 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.6 GO:0032809 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 0.4 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.5 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.5 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 4.1 GO:0001650 fibrillar center(GO:0001650)
0.0 5.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 2.5 GO:0098858 actin-based cell projection(GO:0098858)
0.0 0.5 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.6 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 1.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.8 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.9 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 4.1 GO:0043025 neuronal cell body(GO:0043025)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
9.3 28.0 GO:0008859 exoribonuclease II activity(GO:0008859)
5.5 21.9 GO:0032810 sterol response element binding(GO:0032810)
4.7 18.8 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
2.9 11.6 GO:0016019 peptidoglycan receptor activity(GO:0016019)
2.8 14.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
2.6 608.7 GO:0003823 antigen binding(GO:0003823)
2.5 15.1 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
2.5 7.4 GO:0016429 tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
2.4 9.7 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
2.4 12.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
2.4 12.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
2.0 17.8 GO:0043426 MRF binding(GO:0043426)
1.9 5.7 GO:0016833 oxo-acid-lyase activity(GO:0016833)
1.8 11.0 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
1.7 6.8 GO:0004341 gluconolactonase activity(GO:0004341)
1.5 4.6 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
1.5 12.2 GO:0004111 creatine kinase activity(GO:0004111)
1.5 5.8 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
1.4 5.5 GO:0017089 glycolipid transporter activity(GO:0017089) ceramide binding(GO:0097001)
1.4 5.5 GO:0047685 amine sulfotransferase activity(GO:0047685)
1.3 3.9 GO:0005011 macrophage colony-stimulating factor receptor activity(GO:0005011)
1.2 6.0 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
1.1 3.3 GO:0004878 complement component C5a receptor activity(GO:0004878)
1.1 5.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
1.0 5.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
1.0 9.8 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.9 14.1 GO:0003993 acid phosphatase activity(GO:0003993)
0.9 2.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.9 4.5 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.9 7.9 GO:0004969 histamine receptor activity(GO:0004969)
0.9 3.5 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.8 3.1 GO:0023029 MHC class Ib protein binding(GO:0023029)
0.8 10.9 GO:0045159 myosin II binding(GO:0045159)
0.8 2.3 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.8 11.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.7 6.7 GO:0004565 beta-galactosidase activity(GO:0004565)
0.7 4.5 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.7 8.8 GO:0008430 selenium binding(GO:0008430)
0.7 21.8 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.7 18.0 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.7 2.1 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.7 2.0 GO:0001641 group II metabotropic glutamate receptor activity(GO:0001641)
0.7 2.0 GO:0016784 3-mercaptopyruvate sulfurtransferase activity(GO:0016784)
0.7 2.0 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.6 7.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.6 7.6 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.6 6.3 GO:0031013 troponin I binding(GO:0031013)
0.6 3.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.6 3.1 GO:0050436 microfibril binding(GO:0050436)
0.6 6.7 GO:0004568 chitinase activity(GO:0004568) chitin binding(GO:0008061)
0.6 3.0 GO:0004920 type I interferon receptor activity(GO:0004905) interleukin-10 receptor activity(GO:0004920)
0.6 3.6 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.6 2.4 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.6 4.6 GO:0004467 long-chain fatty acid-CoA ligase activity(GO:0004467)
0.6 4.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.5 2.7 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.5 3.7 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.5 2.6 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.5 2.0 GO:0002046 opsin binding(GO:0002046)
0.5 7.3 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.5 4.7 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.5 3.7 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.5 4.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.5 1.8 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.5 6.8 GO:0015643 toxic substance binding(GO:0015643)
0.5 2.3 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) oxaloacetate decarboxylase activity(GO:0008948)
0.4 1.7 GO:0004077 biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
0.4 2.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.4 2.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.4 2.0 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.4 5.6 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.4 7.6 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
0.4 1.2 GO:0031208 POZ domain binding(GO:0031208)
0.4 1.9 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.4 1.1 GO:0003826 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.4 2.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.4 3.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.4 3.5 GO:0015645 fatty acid ligase activity(GO:0015645)
0.4 3.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.4 37.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.3 9.3 GO:0004622 lysophospholipase activity(GO:0004622)
0.3 4.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 4.3 GO:1990239 steroid hormone binding(GO:1990239)
0.3 4.6 GO:0042609 CD4 receptor binding(GO:0042609)
0.3 4.2 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.3 2.9 GO:0089720 caspase binding(GO:0089720)
0.3 1.3 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.3 9.4 GO:0005521 lamin binding(GO:0005521)
0.3 1.2 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.3 4.6 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.3 1.2 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.3 1.2 GO:0047291 neolactotetraosylceramide alpha-2,3-sialyltransferase activity(GO:0004513) lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.3 1.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.3 4.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.3 2.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559) heme transporter activity(GO:0015232)
0.3 1.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.3 1.1 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.3 0.8 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.3 1.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 2.0 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.2 2.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.2 2.8 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.2 1.1 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.2 3.8 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 2.9 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.2 6.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 3.9 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.2 3.9 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.2 3.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.2 1.1 GO:0070097 delta-catenin binding(GO:0070097)
0.2 7.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.2 2.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 0.8 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 1.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.2 35.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.2 42.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.2 1.5 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2 7.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.2 12.3 GO:0070063 RNA polymerase binding(GO:0070063)
0.2 3.9 GO:0099604 calcium-release channel activity(GO:0015278) ligand-gated calcium channel activity(GO:0099604)
0.2 9.1 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 1.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.2 11.1 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors(GO:0016667)
0.2 1.5 GO:0050682 AF-2 domain binding(GO:0050682)
0.2 1.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.1 5.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.1 8.3 GO:0015485 cholesterol binding(GO:0015485)
0.1 3.9 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.4 GO:0017153 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) sodium:dicarboxylate symporter activity(GO:0017153)
0.1 1.5 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 1.4 GO:0032027 myosin light chain binding(GO:0032027)
0.1 1.8 GO:0015101 organic cation transmembrane transporter activity(GO:0015101)
0.1 2.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 2.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 1.8 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.1 1.4 GO:0051378 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.1 1.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.5 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.1 0.8 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 12.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 1.1 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 1.1 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.7 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 5.8 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.1 0.7 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 2.1 GO:0005542 folic acid binding(GO:0005542)
0.1 2.5 GO:0016790 thiolester hydrolase activity(GO:0016790)
0.1 0.6 GO:0004046 aminoacylase activity(GO:0004046)
0.1 2.4 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 1.1 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 2.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 1.5 GO:1901612 cardiolipin binding(GO:1901612)
0.1 1.8 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 5.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 2.8 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.8 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 5.0 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 4.5 GO:0030507 spectrin binding(GO:0030507)
0.1 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 1.0 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.3 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1 3.3 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.1 2.7 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 6.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 4.8 GO:0097110 scaffold protein binding(GO:0097110)
0.1 0.6 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 0.2 GO:0004948 calcitonin receptor activity(GO:0004948) calcitonin receptor binding(GO:0031716)
0.1 1.8 GO:0071837 HMG box domain binding(GO:0071837)
0.1 1.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 2.0 GO:0005109 frizzled binding(GO:0005109)
0.1 0.9 GO:0004697 protein kinase C activity(GO:0004697)
0.1 3.6 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 1.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 0.2 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.0 3.7 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 1.6 GO:0030332 cyclin binding(GO:0030332)
0.0 0.6 GO:0001163 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 1.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 4.4 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.0 0.6 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 1.0 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 2.8 GO:0019843 rRNA binding(GO:0019843)
0.0 2.2 GO:0005262 calcium channel activity(GO:0005262)
0.0 1.7 GO:0050681 androgen receptor binding(GO:0050681)
0.0 2.7 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.0 0.1 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 4.9 GO:0005178 integrin binding(GO:0005178)
0.0 0.6 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0052795 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 1.2 GO:0015026 coreceptor activity(GO:0015026)
0.0 4.9 GO:0051015 actin filament binding(GO:0051015)
0.0 0.4 GO:0008494 translation activator activity(GO:0008494)
0.0 1.8 GO:0002039 p53 binding(GO:0002039)
0.0 0.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.7 GO:0032452 histone demethylase activity(GO:0032452)
0.0 1.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 5.9 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0001848 complement binding(GO:0001848)
0.0 1.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.4 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 29.9 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.5 12.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.5 38.7 PID HNF3A PATHWAY FOXA1 transcription factor network
0.3 17.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.3 3.7 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.3 12.8 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.3 7.0 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.2 13.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.2 2.1 ST STAT3 PATHWAY STAT3 Pathway
0.2 3.0 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.2 6.5 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.2 31.5 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.2 9.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.2 3.9 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.2 2.2 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.2 9.1 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.2 3.9 PID LPA4 PATHWAY LPA4-mediated signaling events
0.2 14.3 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.2 8.9 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 8.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.2 1.9 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.2 6.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.2 6.7 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 9.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 6.9 PID AP1 PATHWAY AP-1 transcription factor network
0.1 4.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.2 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.1 3.9 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 2.7 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.1 3.5 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 5.3 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 2.1 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1 2.0 SIG PIP3 SIGNALING IN B LYMPHOCYTES Genes related to PIP3 signaling in B lymphocytes
0.1 4.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 5.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.1 3.2 PID AURORA A PATHWAY Aurora A signaling
0.1 2.1 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 3.2 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 1.5 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.8 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.5 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 4.1 PID P73PATHWAY p73 transcription factor network
0.0 9.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 3.1 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 4.8 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.8 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.2 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.6 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 0.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.2 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.8 PID CMYB PATHWAY C-MYB transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 21.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
1.3 12.8 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
1.2 12.0 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
1.1 2.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.8 17.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.7 11.6 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.7 15.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.6 27.2 REACTOME AMYLOIDS Genes involved in Amyloids
0.5 9.2 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.5 15.6 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.5 9.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.5 8.4 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.4 5.4 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.4 6.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.4 4.4 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.4 18.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.4 4.9 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.4 4.8 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.3 32.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.3 5.0 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.3 8.0 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.3 2.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 6.7 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.2 20.0 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.2 1.5 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.2 6.0 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.2 9.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 30.7 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.2 2.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 2.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.2 3.0 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.2 12.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.2 12.0 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.2 1.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.2 3.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.2 1.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2 16.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 10.1 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 2.8 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.2 3.2 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.2 13.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1 18.5 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 7.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 7.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 4.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.1 1.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 2.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 2.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 2.3 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.1 4.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 5.1 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 5.9 REACTOME MEIOSIS Genes involved in Meiosis
0.1 1.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 0.7 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 0.8 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.2 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 0.8 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 3.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 2.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 7.4 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 1.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 2.2 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 1.1 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 2.0 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.1 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.9 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.7 REACTOME FATTY ACID TRIACYLGLYCEROL AND KETONE BODY METABOLISM Genes involved in Fatty acid, triacylglycerol, and ketone body metabolism
0.0 1.6 REACTOME COSTIMULATION BY THE CD28 FAMILY Genes involved in Costimulation by the CD28 family
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 2.6 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 0.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.4 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.5 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.6 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 3.9 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.3 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse