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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ETS1

Z-value: 3.96

Motif logo

Transcription factors associated with ETS1

Gene Symbol Gene ID Gene Info
ENSG00000134954.14 ETS1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ETS1hg38_v1_chr11_-_128522189_1285222080.491.2e-14Click!

Activity profile of ETS1 motif

Sorted Z-values of ETS1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ETS1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr19_+_1077394 61.08 ENST00000590577.2
Rho GTPase activating protein 45
chr2_+_65228122 59.60 ENST00000542850.2
actin related protein 2
chr1_-_224434750 58.14 ENST00000414423.9
ENST00000678917.1
ENST00000678555.1
ENST00000678307.1
WD repeat domain 26
chr21_-_44920855 57.68 ENST00000397854.7
integrin subunit beta 2
chr21_-_44920892 57.03 ENST00000397846.7
ENST00000652462.1
ENST00000302347.10
ENST00000524251.1
integrin subunit beta 2
chr19_-_10194898 54.13 ENST00000359526.9
ENST00000679103.1
ENST00000676610.1
ENST00000678804.1
ENST00000679313.1
ENST00000677946.1
DNA methyltransferase 1
chr1_+_40040219 54.07 ENST00000372797.7
ENST00000372802.5
ENST00000449311.5
cyclase associated actin cytoskeleton regulatory protein 1
chr13_-_46182136 52.51 ENST00000323076.7
lymphocyte cytosolic protein 1
chr20_+_44885679 50.91 ENST00000353703.9
ENST00000372839.7
ENST00000428262.1
ENST00000445830.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta
chr12_-_110450298 49.36 ENST00000426440.5
ENST00000228825.12
actin related protein 2/3 complex subunit 3
chr19_-_10339610 46.93 ENST00000589261.5
ENST00000160262.10
ENST00000590569.1
ENST00000589580.1
ENST00000589249.1
intercellular adhesion molecule 3
chr2_-_229921903 42.18 ENST00000389045.7
ENST00000409677.5
thyroid hormone receptor interactor 12
chr20_-_2470749 42.02 ENST00000381342.7
ENST00000438552.6
small nuclear ribonucleoprotein polypeptides B and B1
chr1_+_40040720 40.47 ENST00000414893.5
ENST00000372792.7
ENST00000372805.8
ENST00000414281.5
ENST00000420216.5
ENST00000372798.5
ENST00000340450.7
ENST00000435719.5
ENST00000427843.5
ENST00000417287.5
ENST00000424977.1
cyclase associated actin cytoskeleton regulatory protein 1
chr17_-_4949037 40.35 ENST00000572383.1
profilin 1
chr10_-_43397220 40.21 ENST00000477108.5
ENST00000544000.5
heterogeneous nuclear ribonucleoprotein F
chr1_-_112704921 40.15 ENST00000414971.1
ENST00000534717.5
ras homolog family member C
chr10_-_119542683 38.56 ENST00000369103.3
regulator of G protein signaling 10
chr5_+_271616 37.71 ENST00000614778.4
ENST00000618970.4
ENST00000628729.2
programmed cell death 6
chr4_-_83114715 37.62 ENST00000426923.2
ENST00000311507.9
ENST00000509973.5
placenta associated 8
chr3_-_64023424 36.32 ENST00000478185.1
ENST00000482510.5
ENST00000497323.5
ENST00000492933.5
ENST00000295901.9
proteasome 26S subunit, non-ATPase 6
chr22_-_36528897 36.08 ENST00000405442.5
ENST00000402116.2
eukaryotic translation initiation factor 3 subunit D
chr1_-_111200633 36.02 ENST00000357640.9
DENN domain containing 2D
chr19_+_35154715 35.13 ENST00000392218.6
ENST00000543307.5
ENST00000392219.7
ENST00000541435.6
ENST00000590686.5
ENST00000342879.7
ENST00000588699.5
FXYD domain containing ion transport regulator 5
chr12_-_112418819 34.84 ENST00000551291.6
ribosomal protein L6
chr5_+_271637 34.82 ENST00000264933.9
ENST00000505221.5
ENST00000509581.5
ENST00000507528.5
programmed cell death 6
chr11_-_58575846 34.81 ENST00000395074.7
leupaxin
chr1_+_16440700 34.62 ENST00000504551.6
ENST00000457722.6
ENST00000337132.10
ENST00000443980.6
NECAP endocytosis associated 2
chr19_+_35154914 34.42 ENST00000423817.7
FXYD domain containing ion transport regulator 5
chr19_-_39335999 34.21 ENST00000602185.5
ENST00000598034.5
ENST00000601387.5
ENST00000595636.1
ENST00000253054.12
ENST00000594700.5
ENST00000597595.6
glia maturation factor gamma
chr3_-_121660892 34.10 ENST00000428394.6
ENST00000314583.8
hematopoietic cell-specific Lyn substrate 1
chr22_-_36529136 34.10 ENST00000216190.13
ENST00000455547.5
eukaryotic translation initiation factor 3 subunit D
chr6_-_31542339 34.09 ENST00000458640.5
DExD-box helicase 39B
chr19_-_46714269 33.43 ENST00000600194.5
protein kinase D2
chr17_-_4948519 33.04 ENST00000225655.6
profilin 1
chr2_+_85577540 32.67 ENST00000263864.10
ENST00000409760.1
vesicle associated membrane protein 8
chr7_+_5045821 32.60 ENST00000353796.7
ENST00000396912.2
ENST00000396904.2
RB associated KRAB zinc finger
RBAK-RBAKDN readthrough
chr17_-_64506616 32.58 ENST00000581697.5
ENST00000450599.7
ENST00000577922.6
DEAD-box helicase 5
chr5_+_65926556 32.37 ENST00000380943.6
ENST00000416865.6
ENST00000380935.5
ENST00000284037.10
erbb2 interacting protein
chr16_-_30193666 32.32 ENST00000651894.2
ENST00000569282.2
ENST00000567436.2
bolA family member 2B
chr12_-_120469571 32.23 ENST00000550458.1
serine and arginine rich splicing factor 9
chr1_-_167518583 32.19 ENST00000392122.3
CD247 molecule
chr19_+_13150386 32.13 ENST00000292433.4
ENST00000587885.1
immediate early response 2
chr19_+_7348930 32.12 ENST00000668164.2
Rho/Rac guanine nucleotide exchange factor 18
chr12_-_92145838 31.89 ENST00000256015.5
BTG anti-proliferation factor 1
chr9_-_86354386 31.62 ENST00000277141.10
ENST00000375963.8
terminal uridylyl transferase 7
chr19_+_49335396 31.08 ENST00000598095.5
ENST00000426897.6
ENST00000323906.9
ENST00000535669.6
ENST00000597602.1
ENST00000595660.1
CD37 molecule
chr9_-_86354423 30.86 ENST00000375960.6
terminal uridylyl transferase 7
chr12_-_118359639 30.10 ENST00000541786.5
ENST00000419821.6
ENST00000541878.5
TAO kinase 3
chr11_-_64245816 29.23 ENST00000542235.1
protein phosphatase 1 regulatory inhibitor subunit 14B
chr3_-_50340933 29.15 ENST00000616212.4
Ras association domain family member 1
chr16_-_66934362 29.13 ENST00000567511.1
ENST00000422424.7
cytosolic iron-sulfur assembly component 2B
chr12_+_6946468 29.00 ENST00000543115.5
ENST00000399448.5
protein tyrosine phosphatase non-receptor type 6
chr6_-_32192630 28.95 ENST00000375040.8
G protein signaling modulator 3
chr20_+_3786772 28.92 ENST00000344256.10
ENST00000379598.9
cell division cycle 25B
chr11_-_67437670 28.74 ENST00000326294.4
protein tyrosine phosphatase receptor type C associated protein
chr1_-_167518521 28.58 ENST00000362089.10
CD247 molecule
chr8_+_22580496 28.43 ENST00000409417.5
PDZ and LIM domain 2
chr1_+_32251239 28.38 ENST00000373564.7
ENST00000482949.5
ENST00000336890.10
ENST00000495610.6
LCK proto-oncogene, Src family tyrosine kinase
chr3_-_50340804 28.32 ENST00000359365.9
ENST00000357043.6
Ras association domain family member 1
chr14_+_22871732 28.24 ENST00000359591.9
LDL receptor related protein 10
chr5_+_134758770 28.21 ENST00000628477.2
ENST00000452510.7
ENST00000354283.8
DEAD-box helicase 46
chr16_-_88651015 28.11 ENST00000568278.1
ENST00000569359.5
ENST00000567174.5
ENST00000261623.8
cytochrome b-245 alpha chain
chr2_+_65227792 27.72 ENST00000260641.10
ENST00000377982.8
actin related protein 2
chr16_-_66934144 27.68 ENST00000568572.5
cytosolic iron-sulfur assembly component 2B
chr11_+_118359572 27.68 ENST00000252108.8
ENST00000431736.6
ubiquitination factor E4A
chr6_-_32192845 27.63 ENST00000487761.5
G protein signaling modulator 3
chr3_-_32502783 27.55 ENST00000205636.4
CKLF like MARVEL transmembrane domain containing 6
chr1_+_32274111 27.53 ENST00000619559.4
ENST00000461712.6
ENST00000373562.7
ENST00000477031.6
ENST00000373557.6
ENST00000333070.4
LCK proto-oncogene, Src family tyrosine kinase
chr6_-_42048648 27.45 ENST00000502771.1
ENST00000508143.5
ENST00000514588.1
ENST00000510503.5
cyclin D3
chr1_-_159924529 27.33 ENST00000320307.8
transgelin 2
chr1_+_198638968 27.27 ENST00000348564.11
ENST00000530727.5
ENST00000442510.8
ENST00000645247.1
ENST00000367367.8
ENST00000367364.5
ENST00000413409.6
protein tyrosine phosphatase receptor type C
chr17_+_4715438 27.27 ENST00000571206.1
arrestin beta 2
chrX_+_119468436 27.15 ENST00000317881.9
solute carrier family 25 member 5
chr17_-_40565459 26.67 ENST00000578085.1
ENST00000246657.2
C-C motif chemokine receptor 7
chr3_-_64023986 26.46 ENST00000394431.6
proteasome 26S subunit, non-ATPase 6
chr11_-_414948 26.41 ENST00000530494.1
ENST00000528209.5
ENST00000528058.1
ENST00000431843.7
single Ig and TIR domain containing
chr7_-_139109337 26.25 ENST00000464606.5
zinc finger CCCH-type containing, antiviral 1
chr1_+_23691742 26.05 ENST00000374550.8
ENST00000643754.2
ribosomal protein L11
chr15_-_65517653 26.01 ENST00000559526.5
ENST00000358939.8
ENST00000560665.1
ENST00000300141.11
dipeptidyl peptidase 8
chr3_+_152268920 25.60 ENST00000495875.6
ENST00000324210.10
ENST00000493459.5
muscleblind like splicing regulator 1
chr15_+_74782069 25.54 ENST00000220003.14
ENST00000439220.6
C-terminal Src kinase
chr14_+_57268963 25.52 ENST00000261558.8
adaptor related protein complex 5 subunit mu 1
chr5_+_96743578 25.36 ENST00000325674.11
calpastatin
chr17_-_31314040 25.36 ENST00000330927.5
ecotropic viral integration site 2B
chr2_+_232550643 25.28 ENST00000409514.5
ENST00000409098.5
ENST00000409495.5
ENST00000409167.7
ENST00000258416.8
ENST00000409322.5
ENST00000409394.5
ENST00000454501.1
eukaryotic translation initiation factor 4E family member 2
chr17_+_45221993 25.26 ENST00000328118.7
formin like 1
chr13_-_30617500 25.15 ENST00000405805.5
high mobility group box 1
chr8_+_22580451 24.96 ENST00000622702.1
ENST00000409141.5
ENST00000265810.8
PDZ and LIM domain 2
chr19_+_16111868 24.91 ENST00000300935.8
ENST00000586682.1
RAB8A, member RAS oncogene family
chr8_+_30095649 24.77 ENST00000518192.5
leptin receptor overlapping transcript like 1
chr16_-_29454347 24.66 ENST00000569622.5
BOLA2-SMG1P6 readthrough
chr19_-_10119886 24.58 ENST00000587146.5
ENST00000253108.9
ENST00000588709.5
eukaryotic translation initiation factor 3 subunit G
chr16_+_30075967 24.43 ENST00000279387.12
ENST00000562664.5
ENST00000627746.2
ENST00000562222.5
protein phosphatase 4 catalytic subunit
chr15_-_65517704 24.37 ENST00000321147.10
dipeptidyl peptidase 8
chr3_-_16513643 24.00 ENST00000334133.9
raftlin, lipid raft linker 1
chr5_+_73498408 23.85 ENST00000335895.12
ENST00000678135.1
ENST00000380591.7
ENST00000677654.1
ENST00000507081.6
basic transcription factor 3
chr1_-_30757767 23.84 ENST00000294507.4
lysosomal protein transmembrane 5
chr2_-_174634566 23.72 ENST00000392547.6
WAS/WASL interacting protein family member 1
chr10_-_26860975 23.65 ENST00000376166.5
ENST00000346832.10
ENST00000376138.7
ENST00000536334.5
ENST00000490841.6
ENST00000376137.8
abl interactor 1
chr5_-_180809811 23.64 ENST00000446023.6
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
chr16_+_50266530 23.58 ENST00000566433.6
ENST00000394697.7
ENST00000673801.1
adenylate cyclase 7
chr13_+_30713477 23.49 ENST00000617770.4
arachidonate 5-lipoxygenase activating protein
chr1_-_206921987 23.45 ENST00000530505.1
ENST00000442471.4
Fc fragment of IgM receptor
chr8_-_101205240 23.42 ENST00000520347.5
ENST00000523922.1
zinc finger protein 706
chr16_+_67029133 23.33 ENST00000290858.11
ENST00000412916.7
ENST00000564034.6
core-binding factor subunit beta
chr17_+_42998264 23.16 ENST00000589037.5
ribosomal protein L27
chr5_+_172983763 23.07 ENST00000519374.6
ENST00000519911.5
ATPase H+ transporting V0 subunit e1
chr3_-_186806445 23.07 ENST00000418288.5
ENST00000296273.7
replication factor C subunit 4
chr9_-_35103178 23.03 ENST00000452248.6
ENST00000619795.4
stomatin like 2
chr1_-_153545793 23.01 ENST00000354332.8
ENST00000368716.9
S100 calcium binding protein A4
chr5_-_150904971 22.97 ENST00000394226.2
ENST00000274599.10
ENST00000418587.6
ENST00000446148.6
zinc finger protein 300
chr2_+_68774782 22.93 ENST00000409030.7
ENST00000409220.5
Rho GTPase activating protein 25
chr5_-_150904789 22.93 ENST00000427179.5
zinc finger protein 300
chr12_-_112409305 22.92 ENST00000549847.5
ribosomal protein L6
chr17_+_51165815 22.82 ENST00000513177.5
NME/NM23 nucleoside diphosphate kinase 2
chr19_-_14419331 22.64 ENST00000242776.9
DExD-box helicase 39A
chr12_+_25052732 22.41 ENST00000547044.5
inositol 1,4,5-triphosphate receptor associated 2
chr3_-_131502946 22.35 ENST00000512877.1
ENST00000264995.8
ENST00000511168.5
ENST00000425847.6
mitochondrial ribosomal protein L3
chr8_-_101204697 22.25 ENST00000517844.5
zinc finger protein 706
chr15_-_90233902 22.24 ENST00000328649.11
ENST00000650306.1
calcium and integrin binding 1
chr9_-_35103108 22.13 ENST00000356493.10
stomatin like 2
chr19_-_10119863 22.09 ENST00000589454.5
eukaryotic translation initiation factor 3 subunit G
chr9_+_128689948 22.08 ENST00000372688.8
ENST00000372686.5
SET nuclear proto-oncogene
chr15_-_55196608 22.07 ENST00000677989.1
ENST00000562895.2
ENST00000569386.2
ribosomal L24 domain containing 1
chr12_+_25052634 21.99 ENST00000548766.5
inositol 1,4,5-triphosphate receptor associated 2
chr15_-_55196899 21.88 ENST00000677147.1
ENST00000260443.9
ENST00000677730.1
ribosomal L24 domain containing 1
chr5_+_110738983 21.81 ENST00000355943.8
ENST00000447245.6
solute carrier family 25 member 46
chr7_+_141738343 21.78 ENST00000498107.5
ENST00000265304.11
ENST00000467681.5
ENST00000465582.5
ENST00000463093.5
single stranded DNA binding protein 1
chr1_+_154974653 21.73 ENST00000368439.5
CDC28 protein kinase regulatory subunit 1B
chr17_+_42998779 21.71 ENST00000586277.5
ribosomal protein L27
chr16_+_30472733 21.58 ENST00000356798.11
ENST00000433423.2
integrin subunit alpha L
chr10_-_26860922 21.49 ENST00000376142.6
ENST00000359188.8
ENST00000376140.4
ENST00000376139.6
ENST00000376160.5
abl interactor 1
chr7_+_141738321 21.45 ENST00000612337.4
single stranded DNA binding protein 1
chr2_+_200889327 21.43 ENST00000426253.5
ENST00000454952.1
ENST00000651500.1
ENST00000409020.6
ENST00000359683.8
NGG1 interacting factor 3 like 1
chr15_-_90234046 21.43 ENST00000612800.1
calcium and integrin binding 1
chr4_-_102825854 21.20 ENST00000350435.11
ubiquitin conjugating enzyme E2 D3
chr1_-_20661356 21.19 ENST00000602624.7
ENST00000464364.1
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
chr2_+_171922442 21.17 ENST00000264108.5
histone acetyltransferase 1
chr17_+_42998379 21.08 ENST00000253788.12
ENST00000589913.6
ribosomal protein L27
chr10_-_26860888 21.05 ENST00000376170.8
abl interactor 1
chr6_+_110874775 20.92 ENST00000675380.1
ENST00000368882.8
ENST00000368877.9
ENST00000368885.8
ENST00000672937.2
adenosylmethionine decarboxylase 1
chr5_+_172983789 20.87 ENST00000265093.4
ENST00000517669.1
ATPase H+ transporting V0 subunit e1
chr12_-_51324091 20.83 ENST00000604560.6
bridging integrator 2
chr17_-_17281232 20.83 ENST00000417352.5
ENST00000268717.10
COP9 signalosome subunit 3
chr3_+_184362991 20.73 ENST00000430783.5
RNA polymerase II, I and III subunit H
chr8_+_30095400 20.73 ENST00000321250.13
ENST00000518001.1
ENST00000520682.5
ENST00000442880.6
ENST00000523116.5
leptin receptor overlapping transcript like 1
chr11_+_75399508 20.65 ENST00000531188.6
ENST00000530164.5
ENST00000422465.6
ENST00000278572.10
ENST00000534440.5
ENST00000527446.5
ENST00000526608.5
ENST00000527273.5
ENST00000524851.5
ribosomal protein S3
chr1_-_156020789 20.53 ENST00000531917.5
ENST00000480567.5
ENST00000526212.2
ENST00000529008.5
ENST00000496742.5
ENST00000295702.9
signal sequence receptor subunit 2
chr6_-_31541937 20.43 ENST00000456662.5
ENST00000431908.5
ENST00000456976.5
ENST00000428450.5
ENST00000418897.5
ENST00000396172.6
ENST00000419020.1
ENST00000428098.5
DExD-box helicase 39B
chr5_-_180810086 20.42 ENST00000506889.1
ENST00000393340.7
alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
chr3_+_184363427 20.41 ENST00000429568.1
RNA polymerase II, I and III subunit H
chr11_+_10751203 20.22 ENST00000361367.7
CTR9 homolog, Paf1/RNA polymerase II complex component
chr3_+_184363387 20.21 ENST00000452961.5
RNA polymerase II, I and III subunit H
chr2_+_143129379 20.13 ENST00000295095.11
Rho GTPase activating protein 15
chr2_-_229921963 20.07 ENST00000343290.5
ENST00000389044.8
ENST00000675453.1
ENST00000675903.1
ENST00000283943.9
thyroid hormone receptor interactor 12
chr12_+_75480800 20.06 ENST00000456650.7
GLI pathogenesis related 1
chr4_-_102825526 19.98 ENST00000504211.5
ENST00000508476.5
ubiquitin conjugating enzyme E2 D3
chr3_-_10321041 19.94 ENST00000397109.7
ENST00000428626.5
ENST00000445064.1
ENST00000431352.1
ENST00000397117.5
ENST00000337354.8
ENST00000383801.6
ENST00000432213.1
ENST00000350697.8
SEC13 homolog, nuclear pore and COPII coat complex component
chrX_+_24054931 19.91 ENST00000253039.9
ENST00000423068.1
eukaryotic translation initiation factor 2 subunit gamma
chr16_+_668094 19.83 ENST00000563134.5
ENST00000315082.9
ras homolog family member T2
chr8_+_73991345 19.80 ENST00000284818.7
ENST00000518893.1
lymphocyte antigen 96
chr17_-_78128778 19.79 ENST00000589553.5
transmembrane channel like 6
chr11_-_3840942 19.72 ENST00000351018.5
ras homolog family member G
chr14_+_69767093 19.71 ENST00000394366.6
serine and arginine rich splicing factor 5
chr1_-_206921867 19.71 ENST00000628511.2
ENST00000367091.8
Fc fragment of IgM receptor
chr15_-_65517244 19.63 ENST00000341861.9
dipeptidyl peptidase 8
chr16_+_30472700 19.62 ENST00000358164.9
integrin subunit alpha L
chr2_+_218217131 19.53 ENST00000420104.5
ENST00000315717.10
ENST00000295685.14
actin related protein 2/3 complex subunit 2
chr10_+_73744346 19.45 ENST00000345254.9
ENST00000339365.2
SEC24 homolog C, COPII coat complex component
chr13_+_28659100 19.41 ENST00000460403.1
ENST00000380842.5
proteasome maturation protein
chr11_-_64317528 19.35 ENST00000308774.6
ENST00000544844.6
tRNA methyltransferase subunit 11-2
chr11_-_126268810 19.22 ENST00000332118.11
SRP receptor subunit alpha
chr11_+_237016 19.21 ENST00000352303.9
proteasome 26S subunit, non-ATPase 13
chr17_+_45221854 19.21 ENST00000331495.8
formin like 1
chr12_-_120469655 19.20 ENST00000229390.8
serine and arginine rich splicing factor 9
chr16_-_28211476 19.15 ENST00000569951.1
ENST00000565698.5
exportin 6
chr18_+_3247415 19.10 ENST00000579226.5
myosin light chain 12A
chr20_-_47355657 19.10 ENST00000311275.11
zinc finger MYND-type containing 8
chr2_-_152717451 19.02 ENST00000545856.7
ENST00000493468.7
ENST00000448428.2
pre-mRNA processing factor 40 homolog A
chr4_-_102828022 18.90 ENST00000502690.5
ubiquitin conjugating enzyme E2 D3
chr6_+_31666128 18.90 ENST00000375865.6
ENST00000375866.2
casein kinase 2 beta
chr2_+_200889411 18.85 ENST00000409357.5
ENST00000409129.2
NGG1 interacting factor 3 like 1
chr1_-_20661518 18.77 ENST00000415136.6
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit
chr11_+_236957 18.75 ENST00000532097.6
ENST00000431206.6
ENST00000528906.5
ENST00000621534.4
proteasome 26S subunit, non-ATPase 13
chr5_+_96743536 18.75 ENST00000515663.5
calpastatin
chr19_+_41262480 18.75 ENST00000352456.7
ENST00000595018.5
ENST00000597725.5
heterogeneous nuclear ribonucleoprotein U like 1
chr5_+_168486462 18.74 ENST00000231572.8
ENST00000626454.1
arginyl-tRNA synthetase 1
chr2_-_224982420 18.72 ENST00000645028.1
dedicator of cytokinesis 10
chr1_-_159925496 18.68 ENST00000368097.9
transgelin 2
chr22_-_19479160 18.67 ENST00000399523.5
ENST00000421968.6
ENST00000263202.15
ENST00000447868.5
ubiquitin recognition factor in ER associated degradation 1
chr22_+_39502320 18.64 ENST00000404569.5
mitochondrial elongation factor 1
chr11_-_67353503 18.61 ENST00000539074.1
ENST00000530584.5
ENST00000531239.2
ENST00000312419.8
ENST00000529704.5
DNA polymerase delta 4, accessory subunit
chr5_+_163505564 18.60 ENST00000421814.6
ENST00000518095.5
ENST00000321757.11
methionine adenosyltransferase 2B
chr6_-_85642877 18.57 ENST00000369622.8
synaptotagmin binding cytoplasmic RNA interacting protein
chr11_-_72721908 18.56 ENST00000426523.5
ENST00000429686.5
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr18_+_657637 18.54 ENST00000323274.15
thymidylate synthetase
chr13_-_36999295 18.48 ENST00000679673.1
ENST00000679572.1
ENST00000239891.4
ENST00000681763.1
ENST00000680671.1
ENST00000680012.1
ENST00000679837.1
ENST00000443765.6
ALG5 dolichyl-phosphate beta-glucosyltransferase
chr1_+_84479239 18.48 ENST00000370656.5
ENST00000370654.6
ribosome production factor 1 homolog
chr18_+_3247778 18.46 ENST00000217652.8
ENST00000578611.5
ENST00000583449.1
myosin light chain 12A

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
29.1 87.3 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
23.4 70.2 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
23.2 69.6 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
15.1 45.2 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
14.4 57.6 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
13.4 13.4 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
12.5 12.5 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
12.4 49.7 GO:0018106 peptidyl-histidine phosphorylation(GO:0018106)
11.4 22.8 GO:2000653 regulation of genetic imprinting(GO:2000653)
11.3 79.2 GO:1902915 negative regulation of histone ubiquitination(GO:0033183) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
11.0 44.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
10.9 43.7 GO:0007113 endomitotic cell cycle(GO:0007113)
10.9 32.7 GO:1903595 positive regulation of histamine secretion by mast cell(GO:1903595)
10.9 32.6 GO:0090149 mitochondrial membrane fission(GO:0090149)
10.8 54.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
10.3 31.0 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
9.7 58.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
9.4 28.1 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
9.1 36.6 GO:0019860 uracil metabolic process(GO:0019860)
9.1 27.3 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
8.9 62.6 GO:1904431 positive regulation of t-circle formation(GO:1904431)
8.9 26.7 GO:0097026 dendritic cell dendrite assembly(GO:0097026) regulation of dendritic cell dendrite assembly(GO:2000547)
8.8 43.9 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
8.6 51.6 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
8.2 41.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
8.1 24.4 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
8.0 40.1 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
8.0 63.8 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
7.5 30.0 GO:0002357 defense response to tumor cell(GO:0002357)
7.4 51.5 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
6.9 6.9 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
6.9 27.5 GO:0039507 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
6.8 27.3 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
6.8 47.8 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
6.8 27.3 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
6.7 20.1 GO:1903973 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973)
6.6 26.3 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
6.5 26.1 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
6.5 32.4 GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
6.4 19.3 GO:0070476 peptidyl-glutamine methylation(GO:0018364) RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
6.4 102.5 GO:0043248 proteasome assembly(GO:0043248)
6.4 44.5 GO:0000821 regulation of arginine metabolic process(GO:0000821)
6.3 113.9 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
6.3 25.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) negative regulation of apoptotic cell clearance(GO:2000426)
6.3 25.0 GO:0045048 protein insertion into ER membrane(GO:0045048)
6.1 49.0 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
6.1 18.4 GO:0007174 epidermal growth factor catabolic process(GO:0007174)
6.1 24.5 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
6.1 54.7 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
5.9 59.1 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
5.8 122.8 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
5.8 23.3 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
5.8 11.6 GO:0009826 unidimensional cell growth(GO:0009826)
5.6 73.4 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
5.6 16.8 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
5.6 27.8 GO:0030242 pexophagy(GO:0030242)
5.5 49.9 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
5.4 49.0 GO:0046070 dGTP metabolic process(GO:0046070)
5.4 10.9 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
5.4 16.2 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
5.4 21.4 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
5.3 5.3 GO:1903094 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
5.3 78.9 GO:1903297 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
5.1 35.8 GO:0015866 ADP transport(GO:0015866)
5.1 5.1 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
4.9 78.7 GO:0051014 actin filament severing(GO:0051014)
4.9 14.7 GO:0002188 translation reinitiation(GO:0002188)
4.9 19.6 GO:1902463 protein localization to cell leading edge(GO:1902463)
4.8 14.5 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
4.7 14.1 GO:1903004 regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006)
4.7 14.1 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
4.7 23.5 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
4.6 18.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
4.6 23.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
4.6 13.7 GO:1904732 regulation of electron carrier activity(GO:1904732)
4.6 36.4 GO:0002457 T cell antigen processing and presentation(GO:0002457)
4.5 31.4 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
4.4 61.8 GO:1904871 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
4.3 13.0 GO:0090234 regulation of kinetochore assembly(GO:0090234)
4.3 17.2 GO:0002441 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
4.3 25.5 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
4.2 16.9 GO:0002084 protein depalmitoylation(GO:0002084)
4.2 12.6 GO:0030327 prenylated protein catabolic process(GO:0030327)
4.1 37.0 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
4.1 28.6 GO:0007144 female meiosis I(GO:0007144)
4.0 16.0 GO:0043060 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
4.0 19.8 GO:0034128 detection of lipopolysaccharide(GO:0032497) negative regulation of MyD88-independent toll-like receptor signaling pathway(GO:0034128)
4.0 15.8 GO:0042631 cellular response to water deprivation(GO:0042631)
3.9 11.8 GO:0016080 synaptic vesicle targeting(GO:0016080)
3.9 15.6 GO:0033625 positive regulation of integrin activation(GO:0033625)
3.9 15.4 GO:0035261 external genitalia morphogenesis(GO:0035261)
3.8 15.4 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
3.8 22.9 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
3.7 11.2 GO:0045799 mRNA export from nucleus in response to heat stress(GO:0031990) positive regulation of chromatin assembly or disassembly(GO:0045799)
3.7 15.0 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
3.7 81.6 GO:0097320 membrane tubulation(GO:0097320)
3.6 14.6 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
3.6 25.3 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
3.6 28.8 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
3.6 10.8 GO:0090402 oncogene-induced cell senescence(GO:0090402)
3.5 7.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
3.5 63.1 GO:0035855 megakaryocyte development(GO:0035855)
3.5 10.5 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
3.5 13.8 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
3.4 13.7 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
3.4 10.1 GO:0010796 regulation of multivesicular body size(GO:0010796)
3.3 63.4 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
3.3 26.1 GO:0006348 chromatin silencing at telomere(GO:0006348)
3.2 13.0 GO:1901873 regulation of post-translational protein modification(GO:1901873)
3.2 22.7 GO:0032218 riboflavin transport(GO:0032218)
3.2 38.6 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
3.2 51.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
3.1 105.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
3.1 15.5 GO:0090168 Golgi reassembly(GO:0090168)
3.1 43.2 GO:0051096 positive regulation of helicase activity(GO:0051096)
3.1 46.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
3.1 46.0 GO:0007220 Notch receptor processing(GO:0007220)
3.0 33.5 GO:0002315 marginal zone B cell differentiation(GO:0002315)
3.0 15.1 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
3.0 27.2 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
3.0 21.1 GO:0007000 nucleolus organization(GO:0007000)
3.0 9.0 GO:1901355 response to rapamycin(GO:1901355)
3.0 20.9 GO:0008295 spermine metabolic process(GO:0008215) spermidine biosynthetic process(GO:0008295)
3.0 8.9 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
3.0 29.6 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
2.9 5.9 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
2.9 8.8 GO:0071226 response to molecule of fungal origin(GO:0002238) cellular response to molecule of fungal origin(GO:0071226)
2.9 76.3 GO:0097341 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341)
2.9 11.7 GO:0033182 regulation of histone ubiquitination(GO:0033182)
2.9 8.8 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
2.9 49.0 GO:0071803 positive regulation of podosome assembly(GO:0071803)
2.9 23.0 GO:0039533 regulation of MDA-5 signaling pathway(GO:0039533)
2.8 22.8 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
2.8 8.5 GO:0035927 RNA import into mitochondrion(GO:0035927)
2.8 33.8 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
2.8 16.7 GO:0097338 response to clozapine(GO:0097338)
2.8 8.4 GO:0051684 maintenance of Golgi location(GO:0051684)
2.8 44.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
2.7 32.6 GO:0070987 error-free translesion synthesis(GO:0070987)
2.7 10.9 GO:2000630 positive regulation of miRNA metabolic process(GO:2000630)
2.7 10.8 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
2.7 45.7 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
2.6 108.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
2.6 116.1 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
2.6 94.6 GO:0097421 liver regeneration(GO:0097421)
2.6 13.1 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
2.6 49.7 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
2.6 13.0 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
2.6 23.4 GO:0048296 isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298)
2.6 13.0 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
2.6 20.5 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
2.5 7.6 GO:0014858 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle cell proliferation(GO:0014858) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
2.5 7.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
2.5 7.4 GO:0060957 endocardial cell fate commitment(GO:0060957) endocardial cushion cell differentiation(GO:0061443) endocardial cushion cell fate commitment(GO:0061445)
2.5 7.4 GO:0070837 dehydroascorbic acid transport(GO:0070837)
2.5 31.9 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
2.4 7.2 GO:0072425 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
2.4 37.6 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
2.3 4.7 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
2.3 20.9 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
2.3 32.5 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
2.3 111.3 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
2.3 16.1 GO:0080009 mRNA methylation(GO:0080009)
2.3 6.9 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
2.3 6.9 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
2.2 11.1 GO:0019348 dolichol metabolic process(GO:0019348)
2.2 6.7 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
2.2 4.4 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
2.2 87.8 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
2.1 17.0 GO:0002353 kinin cascade(GO:0002254) plasma kallikrein-kinin cascade(GO:0002353)
2.1 2.1 GO:0042223 regulation of interleukin-3 production(GO:0032672) positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401)
2.1 65.4 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
2.1 6.3 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
2.1 6.3 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
2.0 8.2 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
2.0 44.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
2.0 49.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
2.0 176.3 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent(GO:0002479)
2.0 63.4 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
2.0 7.9 GO:0035407 histone H3-T11 phosphorylation(GO:0035407)
2.0 11.8 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
1.9 38.6 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
1.9 240.8 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
1.9 5.8 GO:1903939 snoRNA localization(GO:0048254) negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939) negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
1.9 5.8 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
1.9 19.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
1.9 13.1 GO:0051013 microtubule severing(GO:0051013)
1.9 7.5 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
1.8 16.6 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
1.8 42.5 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
1.8 14.7 GO:0006013 mannose metabolic process(GO:0006013)
1.8 18.2 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
1.8 3.5 GO:0060528 regulation of translational initiation by iron(GO:0006447) secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
1.8 15.9 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
1.8 61.3 GO:0070207 protein homotrimerization(GO:0070207)
1.7 24.4 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
1.7 62.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
1.7 8.6 GO:1903232 melanosome assembly(GO:1903232)
1.7 11.9 GO:0071569 protein ufmylation(GO:0071569)
1.7 8.5 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
1.7 13.5 GO:0071763 nuclear membrane organization(GO:0071763)
1.7 10.1 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
1.7 20.2 GO:0090435 protein localization to nuclear envelope(GO:0090435)
1.7 5.0 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
1.6 11.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
1.6 11.3 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
1.6 23.9 GO:0000338 protein deneddylation(GO:0000338)
1.6 48.1 GO:0090383 phagosome acidification(GO:0090383)
1.5 18.5 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.5 70.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
1.5 19.8 GO:0006983 ER overload response(GO:0006983)
1.5 33.4 GO:0035518 histone H2A monoubiquitination(GO:0035518)
1.5 9.0 GO:0042256 mature ribosome assembly(GO:0042256)
1.5 85.8 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
1.5 18.0 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
1.5 1.5 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
1.5 4.5 GO:0051182 coenzyme transport(GO:0051182)
1.5 40.4 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
1.5 4.5 GO:0034499 late endosome to Golgi transport(GO:0034499)
1.5 1.5 GO:0035711 T-helper 1 cell activation(GO:0035711)
1.4 36.1 GO:0006144 purine nucleobase metabolic process(GO:0006144)
1.4 11.6 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
1.4 2.9 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
1.4 4.2 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
1.4 20.7 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
1.4 23.0 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
1.3 18.6 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
1.3 39.9 GO:0008053 mitochondrial fusion(GO:0008053)
1.3 9.3 GO:1903378 positive regulation of oxidative stress-induced neuron death(GO:1903223) positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
1.3 11.9 GO:0071578 zinc II ion transmembrane import(GO:0071578)
1.3 21.2 GO:0006228 UTP biosynthetic process(GO:0006228)
1.3 6.6 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
1.3 16.9 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
1.3 45.0 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
1.3 20.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
1.3 5.1 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
1.3 10.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
1.3 5.0 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
1.2 11.2 GO:0009249 protein lipoylation(GO:0009249)
1.2 3.7 GO:0045553 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759) TRAIL biosynthetic process(GO:0045553) regulation of TRAIL biosynthetic process(GO:0045554) positive regulation of TRAIL biosynthetic process(GO:0045556)
1.2 3.6 GO:0034769 basement membrane disassembly(GO:0034769)
1.2 4.8 GO:0016240 autophagosome docking(GO:0016240)
1.2 4.8 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
1.2 7.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.2 10.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) positive regulation of viral entry into host cell(GO:0046598)
1.2 2.4 GO:0061635 regulation of protein complex stability(GO:0061635)
1.2 11.6 GO:0035331 negative regulation of hippo signaling(GO:0035331)
1.2 13.8 GO:0035562 negative regulation of chromatin binding(GO:0035562)
1.1 19.5 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
1.1 10.3 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
1.1 4.5 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
1.1 15.9 GO:0090161 Golgi ribbon formation(GO:0090161)
1.1 7.9 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
1.1 11.2 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
1.1 37.9 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
1.1 10.0 GO:0035897 proteolysis in other organism(GO:0035897)
1.1 13.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
1.1 8.8 GO:0016139 glycoside catabolic process(GO:0016139)
1.1 31.7 GO:0060216 definitive hemopoiesis(GO:0060216)
1.1 4.4 GO:0036229 glutamine secretion(GO:0010585) L-glutamine import(GO:0036229) L-glutamine import into cell(GO:1903803)
1.1 3.3 GO:0048213 Golgi vesicle prefusion complex stabilization(GO:0048213)
1.1 5.4 GO:2000210 positive regulation of anoikis(GO:2000210)
1.1 6.5 GO:0002857 natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002420) natural killer cell mediated immune response to tumor cell(GO:0002423) regulation of natural killer cell mediated immune response to tumor cell(GO:0002855) positive regulation of natural killer cell mediated immune response to tumor cell(GO:0002857) regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002858) positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002860)
1.1 18.1 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
1.1 101.2 GO:0006413 translational initiation(GO:0006413)
1.0 6.3 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
1.0 15.3 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
1.0 29.4 GO:0043555 regulation of translation in response to stress(GO:0043555)
1.0 72.9 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
1.0 4.9 GO:0071895 odontoblast differentiation(GO:0071895)
1.0 15.6 GO:2001204 regulation of osteoclast development(GO:2001204)
1.0 7.8 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
1.0 9.7 GO:0014894 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
1.0 8.7 GO:0007008 outer mitochondrial membrane organization(GO:0007008) protein import into mitochondrial outer membrane(GO:0045040) establishment of protein localization to mitochondrial membrane(GO:0090151)
1.0 7.7 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
1.0 22.1 GO:0035067 negative regulation of histone acetylation(GO:0035067)
1.0 21.0 GO:0016246 RNA interference(GO:0016246)
1.0 19.1 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.9 8.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.9 24.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.9 5.3 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.9 12.4 GO:0001783 B cell apoptotic process(GO:0001783)
0.9 194.3 GO:0038093 Fc receptor signaling pathway(GO:0038093)
0.9 9.6 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.9 18.1 GO:0030220 platelet formation(GO:0030220)
0.9 2.6 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.8 8.4 GO:0045116 protein neddylation(GO:0045116)
0.8 32.5 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.8 6.7 GO:0046836 glycolipid transport(GO:0046836)
0.8 10.8 GO:0007143 female meiotic division(GO:0007143)
0.8 63.0 GO:0006903 vesicle targeting(GO:0006903)
0.8 2.5 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.8 9.9 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.8 2.5 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.8 1.6 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.8 2.4 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.8 10.5 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.8 34.4 GO:0002223 innate immune response activating cell surface receptor signaling pathway(GO:0002220) stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.8 19.6 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.8 12.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.8 3.1 GO:0033622 integrin activation(GO:0033622)
0.8 8.4 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.8 5.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.7 7.3 GO:0051601 exocyst localization(GO:0051601)
0.7 16.0 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.7 4.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.7 8.4 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.7 2.8 GO:0070475 rRNA base methylation(GO:0070475)
0.7 6.2 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.7 12.1 GO:0035066 positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.7 2.6 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.7 7.2 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.6 9.7 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.6 3.2 GO:2000644 regulation of receptor catabolic process(GO:2000644)
0.6 8.3 GO:0010826 negative regulation of centrosome duplication(GO:0010826)
0.6 1.9 GO:0019087 transformation of host cell by virus(GO:0019087)
0.6 43.1 GO:0006611 protein export from nucleus(GO:0006611)
0.6 5.0 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108)
0.6 12.5 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.6 27.0 GO:0051865 protein autoubiquitination(GO:0051865)
0.6 41.4 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.6 12.2 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.6 14.9 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.6 9.0 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.6 0.6 GO:0001927 exocyst assembly(GO:0001927)
0.6 5.6 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.6 70.3 GO:0043484 regulation of RNA splicing(GO:0043484)
0.6 5.5 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.5 14.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.5 10.7 GO:0018345 protein palmitoylation(GO:0018345)
0.5 12.3 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.5 4.8 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.5 11.6 GO:0010259 multicellular organism aging(GO:0010259)
0.5 6.8 GO:0032486 Rap protein signal transduction(GO:0032486)
0.5 22.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.5 3.4 GO:0002517 T cell tolerance induction(GO:0002517)
0.5 6.2 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.5 4.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.5 1.4 GO:0072719 cellular response to cisplatin(GO:0072719)
0.5 10.7 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.5 15.3 GO:0005980 glycogen catabolic process(GO:0005980)
0.4 4.0 GO:0032753 positive regulation of interleukin-4 production(GO:0032753)
0.4 1.3 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.4 21.1 GO:0007566 embryo implantation(GO:0007566)
0.4 3.9 GO:0038092 nodal signaling pathway(GO:0038092)
0.4 17.8 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.4 66.8 GO:0008360 regulation of cell shape(GO:0008360)
0.4 5.7 GO:0070911 global genome nucleotide-excision repair(GO:0070911)
0.4 26.7 GO:0048278 vesicle docking(GO:0048278)
0.4 2.8 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.4 7.7 GO:0032480 negative regulation of type I interferon production(GO:0032480)
0.4 199.5 GO:0002283 neutrophil activation involved in immune response(GO:0002283) neutrophil degranulation(GO:0043312)
0.4 2.0 GO:2001023 regulation of response to drug(GO:2001023)
0.4 2.7 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.4 39.7 GO:0006414 translational elongation(GO:0006414)
0.4 3.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.4 1.5 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.4 11.8 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.4 19.9 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.4 2.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.4 1.8 GO:0046618 drug export(GO:0046618)
0.4 5.5 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.4 2.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.4 1.8 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.4 7.5 GO:0031648 protein destabilization(GO:0031648)
0.4 7.4 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.3 2.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.3 2.4 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.3 3.8 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.3 1.0 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.3 79.0 GO:0008380 RNA splicing(GO:0008380)
0.3 1.6 GO:0001315 age-dependent response to oxidative stress(GO:0001306) age-dependent response to reactive oxygen species(GO:0001315) regulation of systemic arterial blood pressure by acetylcholine(GO:0003068) vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure(GO:0003069) regulation of systemic arterial blood pressure by neurotransmitter(GO:0003070) age-dependent general metabolic decline(GO:0007571)
0.3 1.9 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.3 17.9 GO:0045773 positive regulation of axon extension(GO:0045773)
0.3 5.3 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.3 19.5 GO:2000117 negative regulation of cysteine-type endopeptidase activity(GO:2000117)
0.3 16.7 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.3 17.1 GO:0071277 cellular response to calcium ion(GO:0071277)
0.3 5.5 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.3 13.3 GO:0042100 B cell proliferation(GO:0042100)
0.3 5.3 GO:0048268 clathrin coat assembly(GO:0048268)
0.2 10.0 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.2 1.0 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.2 5.4 GO:0050684 regulation of mRNA processing(GO:0050684)
0.2 4.6 GO:0051642 centrosome localization(GO:0051642)
0.2 0.7 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.2 9.4 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.2 8.9 GO:0030183 B cell differentiation(GO:0030183)
0.2 1.7 GO:0050858 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858)
0.2 9.2 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.2 0.2 GO:0071609 chemokine (C-C motif) ligand 5 production(GO:0071609)
0.2 3.7 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.2 1.3 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.2 13.7 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.2 1.1 GO:0018202 peptidyl-histidine modification(GO:0018202)
0.2 6.6 GO:0043171 peptide catabolic process(GO:0043171)
0.2 1.8 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.2 2.5 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.2 7.3 GO:0090175 Wnt signaling pathway, planar cell polarity pathway(GO:0060071) regulation of establishment of planar polarity(GO:0090175)
0.1 0.1 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 4.2 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.8 GO:0051665 membrane raft localization(GO:0051665)
0.1 1.0 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 1.0 GO:0000012 single strand break repair(GO:0000012)
0.1 0.4 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.1 3.3 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.1 0.7 GO:0042791 transcription initiation from RNA polymerase III promoter(GO:0006384) 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.1 0.8 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.1 1.0 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.1 3.9 GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079)
0.1 0.9 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 0.4 GO:1903416 response to glycoside(GO:1903416)
0.1 1.2 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.9 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.4 GO:0015886 heme transport(GO:0015886)
0.0 0.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 1.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 1.0 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.5 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.2 GO:0070525 tRNA threonylcarbamoyladenosine metabolic process(GO:0070525)
0.0 0.1 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.7 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 0.1 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.9 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
26.0 155.9 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
12.2 24.4 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
10.7 107.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
10.0 19.9 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
8.9 178.1 GO:0005885 Arp2/3 protein complex(GO:0005885)
8.4 92.0 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
8.2 89.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
8.1 24.4 GO:0030289 protein phosphatase 4 complex(GO:0030289)
7.2 36.1 GO:1902560 GMP reductase complex(GO:1902560)
7.2 28.8 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
7.0 28.1 GO:0071817 MMXD complex(GO:0071817)
6.8 27.3 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
6.8 20.4 GO:0071001 U4/U6 snRNP(GO:0071001)
6.8 54.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
6.8 81.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
6.8 74.6 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
6.5 116.8 GO:0030127 COPII vesicle coat(GO:0030127)
6.3 56.3 GO:0032010 phagolysosome(GO:0032010)
6.2 18.6 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
6.1 18.4 GO:0032419 extrinsic component of lysosome membrane(GO:0032419)
6.0 18.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
5.9 47.4 GO:0072487 MSL complex(GO:0072487)
5.8 75.9 GO:0005688 U6 snRNP(GO:0005688)
5.7 45.7 GO:0070522 nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
5.7 28.5 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
5.6 90.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
5.5 16.5 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
5.3 47.4 GO:0070765 gamma-secretase complex(GO:0070765)
5.2 20.6 GO:0071159 NF-kappaB complex(GO:0071159)
5.1 15.4 GO:0032116 SMC loading complex(GO:0032116)
5.1 35.9 GO:0005956 protein kinase CK2 complex(GO:0005956)
4.9 4.9 GO:1990111 spermatoproteasome complex(GO:1990111)
4.8 14.5 GO:0008623 CHRAC(GO:0008623)
4.8 61.8 GO:0002199 zona pellucida receptor complex(GO:0002199)
4.7 23.5 GO:0097422 tubular endosome(GO:0097422)
4.4 8.8 GO:0019815 B cell receptor complex(GO:0019815)
4.3 21.7 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
4.3 86.1 GO:0005838 proteasome regulatory particle(GO:0005838)
4.3 111.7 GO:0001891 phagocytic cup(GO:0001891)
4.3 55.8 GO:0031209 SCAR complex(GO:0031209)
4.3 21.4 GO:0042643 actomyosin, actin portion(GO:0042643)
4.2 29.1 GO:0032021 NELF complex(GO:0032021)
4.1 16.3 GO:0070435 Shc-EGFR complex(GO:0070435)
4.0 16.0 GO:0005715 late recombination nodule(GO:0005715)
3.9 35.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
3.9 19.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
3.8 23.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
3.8 15.3 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
3.8 30.5 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
3.8 7.5 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
3.7 18.6 GO:0043625 delta DNA polymerase complex(GO:0043625)
3.7 11.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
3.6 71.9 GO:0042101 T cell receptor complex(GO:0042101)
3.5 378.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
3.5 10.6 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
3.5 10.5 GO:1902737 dendritic filopodium(GO:1902737)
3.4 74.2 GO:0005721 pericentric heterochromatin(GO:0005721)
3.4 10.1 GO:0097441 basilar dendrite(GO:0097441)
3.3 30.0 GO:0044194 cytolytic granule(GO:0044194)
3.2 26.0 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
3.2 16.2 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
3.2 58.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
3.2 16.1 GO:0045293 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
3.2 181.6 GO:0001772 immunological synapse(GO:0001772)
3.2 12.7 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
3.1 15.6 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
3.1 15.5 GO:0036398 TCR signalosome(GO:0036398)
2.9 35.3 GO:0030008 TRAPP complex(GO:0030008)
2.8 28.2 GO:0097255 R2TP complex(GO:0097255)
2.8 25.0 GO:0043020 NADPH oxidase complex(GO:0043020)
2.7 41.2 GO:0032059 bleb(GO:0032059)
2.7 43.9 GO:0033179 proton-transporting two-sector ATPase complex, proton-transporting domain(GO:0033177) proton-transporting V-type ATPase, V0 domain(GO:0033179)
2.7 8.2 GO:0035370 UBC13-UEV1A complex(GO:0035370)
2.7 24.5 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
2.7 8.1 GO:0044611 nuclear pore inner ring(GO:0044611)
2.7 13.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
2.7 98.3 GO:0030125 clathrin vesicle coat(GO:0030125)
2.7 45.1 GO:0032433 filopodium tip(GO:0032433)
2.6 28.9 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
2.6 52.1 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
2.6 23.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
2.6 10.3 GO:0000346 transcription export complex(GO:0000346)
2.5 15.1 GO:0033553 rDNA heterochromatin(GO:0033553)
2.5 19.9 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
2.4 80.8 GO:0030687 preribosome, large subunit precursor(GO:0030687)
2.4 24.0 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
2.4 21.5 GO:0032133 chromosome passenger complex(GO:0032133)
2.4 19.1 GO:0034719 SMN-Sm protein complex(GO:0034719)
2.2 49.0 GO:0071141 SMAD protein complex(GO:0071141)
2.2 10.8 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
2.1 23.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
2.0 40.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
2.0 10.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
2.0 14.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
1.9 28.8 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
1.9 19.0 GO:0005845 mRNA cap binding complex(GO:0005845)
1.9 238.7 GO:0035578 azurophil granule lumen(GO:0035578)
1.9 11.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
1.9 7.4 GO:0048179 activin receptor complex(GO:0048179)
1.9 7.4 GO:0031510 SUMO activating enzyme complex(GO:0031510)
1.8 12.9 GO:0031415 NatA complex(GO:0031415)
1.8 114.8 GO:0035577 azurophil granule membrane(GO:0035577)
1.7 35.0 GO:0005686 U2 snRNP(GO:0005686)
1.7 12.2 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
1.7 8.6 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
1.7 6.8 GO:0070876 SOSS complex(GO:0070876)
1.7 5.1 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
1.7 23.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
1.6 23.6 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
1.5 30.8 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
1.5 7.7 GO:0032044 DSIF complex(GO:0032044)
1.5 6.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
1.5 14.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
1.4 32.4 GO:0030056 hemidesmosome(GO:0030056)
1.4 8.4 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
1.3 10.7 GO:0034709 methylosome(GO:0034709)
1.3 27.5 GO:0097342 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
1.3 14.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
1.2 27.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
1.2 2.5 GO:0097149 centralspindlin complex(GO:0097149)
1.2 67.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
1.2 15.6 GO:0042555 MCM complex(GO:0042555)
1.2 29.7 GO:0031095 platelet dense tubular network membrane(GO:0031095)
1.2 13.0 GO:0030870 Mre11 complex(GO:0030870)
1.2 3.5 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
1.2 10.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
1.1 8.9 GO:0043219 lateral loop(GO:0043219)
1.1 5.6 GO:0005797 Golgi medial cisterna(GO:0005797)
1.1 75.0 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
1.1 16.5 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
1.1 6.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
1.1 10.9 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
1.1 132.3 GO:0017053 transcriptional repressor complex(GO:0017053)
1.1 73.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
1.1 2.1 GO:0055087 Ski complex(GO:0055087)
1.1 39.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
1.1 13.8 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
1.0 45.0 GO:0031201 SNARE complex(GO:0031201)
1.0 16.7 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
1.0 30.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
1.0 16.1 GO:0005662 DNA replication factor A complex(GO:0005662)
1.0 8.6 GO:0042382 paraspeckles(GO:0042382)
1.0 4.8 GO:0044308 axonal spine(GO:0044308)
0.9 5.7 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.9 21.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.9 13.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.9 11.9 GO:0017119 Golgi transport complex(GO:0017119)
0.9 35.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.9 5.3 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.9 402.2 GO:0016607 nuclear speck(GO:0016607)
0.9 14.6 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.9 9.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.8 10.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.8 2.5 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.8 11.8 GO:0042405 nuclear inclusion body(GO:0042405)
0.8 120.9 GO:1904813 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.8 12.7 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.8 7.1 GO:0072546 ER membrane protein complex(GO:0072546)
0.8 18.7 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.8 4.6 GO:0005684 U2-type spliceosomal complex(GO:0005684)
0.8 13.0 GO:0030904 retromer complex(GO:0030904)
0.8 6.8 GO:0071203 WASH complex(GO:0071203)
0.7 4.5 GO:0032584 growth cone membrane(GO:0032584)
0.7 10.3 GO:0005839 proteasome core complex(GO:0005839)
0.7 8.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.7 2.2 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.7 68.7 GO:0070821 tertiary granule membrane(GO:0070821)
0.7 18.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.7 6.8 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.7 14.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.7 7.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.7 13.0 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.6 8.4 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.6 1.9 GO:0005745 m-AAA complex(GO:0005745)
0.6 10.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.6 33.9 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.6 35.4 GO:0043198 dendritic shaft(GO:0043198)
0.6 30.7 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.6 24.9 GO:0045171 intercellular bridge(GO:0045171)
0.6 5.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.5 2.7 GO:0071439 clathrin complex(GO:0071439)
0.5 6.5 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.5 5.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.5 20.5 GO:0090544 BAF-type complex(GO:0090544)
0.5 6.7 GO:0097433 dense body(GO:0097433)
0.5 15.8 GO:0097228 sperm principal piece(GO:0097228)
0.5 37.7 GO:0016459 myosin complex(GO:0016459)
0.5 79.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.5 71.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.5 33.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.5 30.2 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.5 5.0 GO:0016600 flotillin complex(GO:0016600)
0.4 4.0 GO:0032039 integrator complex(GO:0032039)
0.4 12.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.4 4.5 GO:0070449 elongin complex(GO:0070449)
0.4 4.9 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.4 4.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.4 1.1 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.3 43.9 GO:0005884 actin filament(GO:0005884)
0.3 15.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.3 7.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.3 65.4 GO:0072562 blood microparticle(GO:0072562)
0.3 9.4 GO:0032420 stereocilium(GO:0032420)
0.3 23.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.3 1.6 GO:0032009 early phagosome(GO:0032009)
0.3 47.4 GO:0043197 dendritic spine(GO:0043197) neuron spine(GO:0044309)
0.3 14.3 GO:0005771 multivesicular body(GO:0005771)
0.3 1.8 GO:0034448 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.3 2.7 GO:0045495 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.3 5.4 GO:0005720 nuclear heterochromatin(GO:0005720)
0.3 1.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.3 1.4 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.3 0.8 GO:0070939 Dsl1p complex(GO:0070939)
0.2 2.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.2 1.0 GO:0008537 proteasome activator complex(GO:0008537)
0.2 21.5 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.2 6.6 GO:0008180 COP9 signalosome(GO:0008180)
0.2 1.1 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 2.8 GO:0000815 ESCRT III complex(GO:0000815)
0.2 2.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.2 3.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.2 9.5 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 4.2 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.2 2.6 GO:0051233 spindle midzone(GO:0051233)
0.1 0.9 GO:0097450 astrocyte end-foot(GO:0097450) glial limiting end-foot(GO:0097451)
0.1 1.3 GO:0030897 HOPS complex(GO:0030897)
0.1 6.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 16.7 GO:0000922 spindle pole(GO:0000922)
0.1 8.6 GO:0031902 late endosome membrane(GO:0031902)
0.1 11.5 GO:0005903 brush border(GO:0005903)
0.1 0.4 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 32.2 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.1 10.7 GO:0005882 intermediate filament(GO:0005882)
0.1 9.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 0.7 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 2.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 3.4 GO:0005795 Golgi stack(GO:0005795)
0.1 2.9 GO:0005840 ribosome(GO:0005840)
0.1 2.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.2 GO:0000145 exocyst(GO:0000145)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
23.4 70.2 GO:0098808 mRNA cap binding(GO:0098808)
22.3 155.9 GO:0030369 ICAM-3 receptor activity(GO:0030369)
11.2 55.9 GO:0042610 CD8 receptor binding(GO:0042610)
11.0 44.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
10.9 32.7 GO:0044713 GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693)
10.5 42.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
10.0 50.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
9.9 29.7 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
9.1 99.8 GO:0004576 oligosaccharyl transferase activity(GO:0004576)
9.0 81.3 GO:0030621 U4 snRNA binding(GO:0030621)
9.0 54.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
8.5 25.6 GO:0001069 regulatory region RNA binding(GO:0001069)
8.2 49.0 GO:0035500 MH2 domain binding(GO:0035500)
7.9 31.4 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
7.5 29.9 GO:0015207 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
7.2 36.1 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
7.2 28.8 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
7.0 56.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
6.8 27.3 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
6.8 54.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
6.4 44.9 GO:0050815 phosphoserine binding(GO:0050815)
6.3 25.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
6.0 59.6 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
5.8 23.3 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
5.8 17.4 GO:0045131 pre-mRNA branch point binding(GO:0045131)
5.7 34.3 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
5.7 45.7 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
5.6 90.0 GO:0001054 RNA polymerase I activity(GO:0001054)
5.6 16.7 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
5.3 94.5 GO:0008179 adenylate cyclase binding(GO:0008179)
4.9 83.8 GO:0043495 protein anchor(GO:0043495)
4.9 14.7 GO:0055100 adiponectin binding(GO:0055100)
4.8 14.4 GO:0097677 STAT family protein binding(GO:0097677)
4.6 92.7 GO:0005522 profilin binding(GO:0005522)
4.6 18.5 GO:0042134 rRNA primary transcript binding(GO:0042134)
4.6 13.8 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
4.6 27.5 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
4.5 9.0 GO:0008384 IkappaB kinase activity(GO:0008384)
4.5 49.7 GO:0004673 protein histidine kinase activity(GO:0004673)
4.5 58.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
4.4 113.9 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
4.2 25.3 GO:0043120 tumor necrosis factor binding(GO:0043120)
4.2 12.7 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
4.2 20.9 GO:0038051 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
4.2 24.9 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
4.1 24.5 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
4.0 56.2 GO:0008097 5S rRNA binding(GO:0008097)
3.9 23.2 GO:0005047 signal recognition particle binding(GO:0005047)
3.8 15.4 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
3.8 7.7 GO:0051717 inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717)
3.8 45.7 GO:0019869 chloride channel inhibitor activity(GO:0019869)
3.7 7.5 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
3.7 11.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
3.7 40.4 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
3.5 24.8 GO:0048408 epidermal growth factor binding(GO:0048408)
3.5 45.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
3.5 24.6 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
3.5 10.4 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
3.4 10.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
3.3 23.1 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
3.2 13.0 GO:0032184 SUMO polymer binding(GO:0032184)
3.2 22.7 GO:0032217 riboflavin transporter activity(GO:0032217)
3.1 37.1 GO:0015266 protein channel activity(GO:0015266)
3.1 9.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
3.0 18.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
3.0 114.2 GO:0017025 TBP-class protein binding(GO:0017025)
3.0 24.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
2.9 8.6 GO:0035650 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
2.8 45.2 GO:1901612 cardiolipin binding(GO:1901612)
2.8 16.9 GO:0017108 5'-flap endonuclease activity(GO:0017108)
2.8 58.7 GO:0000339 RNA cap binding(GO:0000339)
2.7 54.9 GO:0004697 protein kinase C activity(GO:0004697)
2.7 127.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
2.6 67.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
2.6 15.4 GO:0036033 mediator complex binding(GO:0036033)
2.6 18.0 GO:0061133 endopeptidase activator activity(GO:0061133)
2.6 20.5 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
2.5 22.8 GO:0043426 MRF binding(GO:0043426)
2.5 49.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
2.5 7.4 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
2.5 27.0 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
2.4 92.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
2.4 21.5 GO:0035174 histone serine kinase activity(GO:0035174)
2.4 23.9 GO:0043024 ribosomal small subunit binding(GO:0043024)
2.4 14.1 GO:0016748 succinyltransferase activity(GO:0016748)
2.3 7.0 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
2.3 27.8 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
2.3 16.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
2.3 15.9 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
2.3 15.9 GO:0030368 interleukin-17 receptor activity(GO:0030368)
2.2 8.9 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
2.2 6.7 GO:0098918 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
2.2 17.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
2.2 136.9 GO:0003743 translation initiation factor activity(GO:0003743)
2.2 10.9 GO:0031871 proteinase activated receptor binding(GO:0031871)
2.1 6.4 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
2.1 10.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
2.1 31.8 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
2.1 12.7 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
2.1 6.3 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
2.1 90.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
2.0 26.2 GO:0031681 G-protein beta-subunit binding(GO:0031681)
2.0 64.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
2.0 5.9 GO:0005347 adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) ATP transmembrane transporter activity(GO:0005347) purine nucleotide transmembrane transporter activity(GO:0015216) ADP transmembrane transporter activity(GO:0015217)
2.0 5.9 GO:0004618 copper-exporting ATPase activity(GO:0004008) phosphoglycerate kinase activity(GO:0004618) copper-transporting ATPase activity(GO:0043682)
2.0 7.8 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
1.9 9.7 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
1.9 387.6 GO:0003735 structural constituent of ribosome(GO:0003735)
1.9 38.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
1.9 9.6 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
1.9 5.6 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
1.9 13.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
1.9 48.1 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
1.8 14.6 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.8 9.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
1.8 32.4 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
1.8 16.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
1.8 41.0 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
1.8 12.4 GO:0043274 phospholipase binding(GO:0043274)
1.8 15.9 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
1.7 6.8 GO:0008135 translation factor activity, RNA binding(GO:0008135)
1.7 37.1 GO:0043422 protein kinase B binding(GO:0043422)
1.7 23.6 GO:0004383 guanylate cyclase activity(GO:0004383)
1.7 23.6 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
1.7 10.1 GO:0089720 caspase binding(GO:0089720)
1.7 6.7 GO:0017089 glycolipid transporter activity(GO:0017089)
1.6 4.8 GO:0030156 benzodiazepine receptor binding(GO:0030156)
1.6 36.8 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
1.6 22.4 GO:0017070 U6 snRNA binding(GO:0017070)
1.6 10.9 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
1.6 25.0 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
1.5 7.7 GO:0016531 metallochaperone activity(GO:0016530) copper chaperone activity(GO:0016531)
1.5 9.3 GO:0070990 snRNP binding(GO:0070990)
1.5 16.9 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
1.5 23.0 GO:0050786 RAGE receptor binding(GO:0050786)
1.5 32.0 GO:0032794 GTPase activating protein binding(GO:0032794)
1.5 36.2 GO:0005095 GTPase inhibitor activity(GO:0005095)
1.5 6.0 GO:0001849 complement component C1q binding(GO:0001849)
1.5 10.4 GO:0035325 Toll-like receptor binding(GO:0035325)
1.5 20.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
1.5 14.6 GO:0004689 phosphorylase kinase activity(GO:0004689)
1.4 27.0 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
1.4 36.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
1.4 8.4 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
1.4 8.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
1.4 26.3 GO:0003746 translation elongation factor activity(GO:0003746)
1.4 6.9 GO:0019776 Atg8 ligase activity(GO:0019776)
1.4 28.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
1.4 18.9 GO:0031386 protein tag(GO:0031386)
1.3 6.7 GO:0061676 importin-alpha family protein binding(GO:0061676)
1.3 4.0 GO:0005174 CD40 receptor binding(GO:0005174)
1.3 16.0 GO:0032137 guanine/thymine mispair binding(GO:0032137)
1.3 22.5 GO:0031702 angiotensin receptor binding(GO:0031701) type 1 angiotensin receptor binding(GO:0031702)
1.3 33.0 GO:0031489 myosin V binding(GO:0031489)
1.3 36.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
1.3 13.0 GO:0070087 chromo shadow domain binding(GO:0070087)
1.2 24.9 GO:0032036 myosin heavy chain binding(GO:0032036)
1.2 23.5 GO:0098847 sequence-specific single stranded DNA binding(GO:0098847)
1.2 54.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
1.2 37.9 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
1.2 30.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
1.2 8.4 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
1.2 71.4 GO:0017080 sodium channel regulator activity(GO:0017080)
1.2 35.4 GO:0008143 poly(A) binding(GO:0008143)
1.2 15.3 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
1.2 3.5 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
1.2 5.8 GO:0016936 galactoside binding(GO:0016936)
1.1 17.1 GO:0004143 diacylglycerol kinase activity(GO:0004143)
1.1 6.7 GO:0044388 small protein activating enzyme binding(GO:0044388)
1.1 7.6 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
1.1 66.6 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
1.1 18.3 GO:0016502 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
1.1 36.0 GO:0001671 ATPase activator activity(GO:0001671)
1.1 4.2 GO:0019770 IgG receptor activity(GO:0019770)
1.1 10.5 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
1.0 19.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
1.0 11.3 GO:0033691 sialic acid binding(GO:0033691)
1.0 12.5 GO:0046790 virion binding(GO:0046790)
1.0 16.2 GO:0051400 BH domain binding(GO:0051400)
1.0 97.9 GO:0003697 single-stranded DNA binding(GO:0003697)
0.9 8.5 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.9 217.2 GO:0051015 actin filament binding(GO:0051015)
0.9 11.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.9 13.3 GO:0034185 apolipoprotein binding(GO:0034185)
0.9 3.5 GO:0044323 9-cis retinoic acid receptor activity(GO:0004886) retinoic acid-responsive element binding(GO:0044323) vitamin D response element binding(GO:0070644)
0.8 4.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.8 12.5 GO:0042609 CD4 receptor binding(GO:0042609)
0.8 43.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.8 34.1 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.8 23.2 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.8 8.3 GO:0034452 dynactin binding(GO:0034452)
0.8 2.5 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.8 49.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.8 5.7 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.8 12.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.8 5.7 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.8 33.1 GO:0050699 WW domain binding(GO:0050699)
0.8 3.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.8 17.2 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.8 47.6 GO:0019003 GDP binding(GO:0019003)
0.8 12.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.8 15.3 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.7 37.8 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.7 3.0 GO:0004348 glucosylceramidase activity(GO:0004348)
0.7 24.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.7 14.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.7 32.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.7 13.7 GO:0070064 proline-rich region binding(GO:0070064)
0.7 17.2 GO:0022829 wide pore channel activity(GO:0022829)
0.7 33.9 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.7 1.4 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.7 12.4 GO:0051430 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.7 38.0 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.7 4.1 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.7 8.5 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.7 6.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.6 28.3 GO:0042169 SH2 domain binding(GO:0042169)
0.6 18.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.6 1.9 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.6 14.0 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.6 5.0 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.6 15.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.6 5.5 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.6 26.4 GO:0005080 protein kinase C binding(GO:0005080)
0.6 9.1 GO:0005521 lamin binding(GO:0005521)
0.6 2.4 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.6 5.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.6 11.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.6 10.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.6 2.2 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.6 12.7 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.6 12.1 GO:0008242 omega peptidase activity(GO:0008242)
0.5 2.7 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.5 2.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.5 4.7 GO:0032051 clathrin light chain binding(GO:0032051)
0.5 4.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.5 19.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.5 16.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.5 1.0 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.5 6.9 GO:0050693 LBD domain binding(GO:0050693)
0.5 5.8 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.5 4.8 GO:0015385 sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.5 2.8 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.5 14.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.5 13.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.5 1.8 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.5 2.3 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.5 36.5 GO:0003725 double-stranded RNA binding(GO:0003725)
0.4 12.1 GO:0042287 MHC protein binding(GO:0042287)
0.4 7.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.4 6.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.4 2.2 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.4 12.2 GO:0071949 FAD binding(GO:0071949)
0.4 4.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.4 0.4 GO:0008413 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539)
0.4 25.9 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.4 12.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.4 11.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.4 16.1 GO:0042805 actinin binding(GO:0042805)
0.4 1.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.4 1.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.4 5.4 GO:0008517 folic acid transporter activity(GO:0008517)
0.4 5.0 GO:0010857 calcium-dependent protein serine/threonine kinase activity(GO:0009931) calcium-dependent protein kinase activity(GO:0010857)
0.4 1.1 GO:0031626 beta-endorphin binding(GO:0031626)
0.4 3.9 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.4 1.4 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.4 42.5 GO:0005262 calcium channel activity(GO:0005262)
0.3 48.3 GO:0005178 integrin binding(GO:0005178)
0.3 3.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.3 0.7 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.3 13.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.3 6.7 GO:0017091 AU-rich element binding(GO:0017091)
0.3 7.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.3 7.3 GO:0051018 protein kinase A binding(GO:0051018)
0.3 63.6 GO:0003924 GTPase activity(GO:0003924)
0.3 20.0 GO:0035064 methylated histone binding(GO:0035064)
0.3 6.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.3 36.3 GO:0047485 protein N-terminus binding(GO:0047485)
0.3 14.6 GO:0003684 damaged DNA binding(GO:0003684)
0.3 16.4 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.3 1.2 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.3 26.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.3 8.0 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.3 1.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.3 1.4 GO:0001164 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.3 7.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.3 4.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.3 1.0 GO:0034191 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) apolipoprotein A-I receptor binding(GO:0034191)
0.3 2.3 GO:0016805 dipeptidase activity(GO:0016805)
0.2 3.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.2 5.5 GO:0043236 laminin binding(GO:0043236)
0.2 9.6 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.2 1.5 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.2 2.9 GO:0097602 cullin family protein binding(GO:0097602)
0.2 1.6 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.2 6.2 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.2 5.9 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.2 1.0 GO:1990460 leptin receptor binding(GO:1990460)
0.2 7.4 GO:0017046 peptide hormone binding(GO:0017046)
0.2 3.5 GO:0005537 mannose binding(GO:0005537)
0.2 0.5 GO:0003696 satellite DNA binding(GO:0003696) centromeric DNA binding(GO:0019237)
0.2 2.0 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.1 9.9 GO:0001618 virus receptor activity(GO:0001618)
0.1 22.6 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 3.4 GO:0070403 NAD+ binding(GO:0070403)
0.1 5.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 2.0 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.1 1.8 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.1 12.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 0.4 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.1 13.2 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 0.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 4.9 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 0.7 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 6.4 GO:0008565 protein transporter activity(GO:0008565)
0.1 1.4 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 1.0 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 7.0 GO:0035326 enhancer binding(GO:0035326)
0.1 2.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 19.9 GO:0005096 GTPase activator activity(GO:0005096)
0.1 0.5 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.1 0.3 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 3.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.4 GO:0015232 heme transporter activity(GO:0015232)
0.0 1.5 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.6 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 17.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
4.3 208.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
4.2 362.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
4.0 167.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
3.5 328.3 PID RAC1 PATHWAY RAC1 signaling pathway
3.4 80.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
3.1 24.4 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
2.9 41.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
2.7 217.6 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
2.5 9.9 PID IL27 PATHWAY IL27-mediated signaling events
1.5 32.1 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
1.5 141.2 PID NOTCH PATHWAY Notch signaling pathway
1.4 31.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
1.4 27.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
1.3 41.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
1.3 44.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
1.2 45.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
1.1 16.7 PID IL3 PATHWAY IL3-mediated signaling events
1.1 131.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
1.1 75.6 PID ILK PATHWAY Integrin-linked kinase signaling
1.1 61.1 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
1.0 5.2 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
1.0 54.1 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
1.0 23.6 PID LPA4 PATHWAY LPA4-mediated signaling events
1.0 42.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
1.0 30.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
1.0 34.8 PID BCR 5PATHWAY BCR signaling pathway
0.8 24.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.8 37.5 PID ATR PATHWAY ATR signaling pathway
0.7 34.6 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.6 16.2 PID IFNG PATHWAY IFN-gamma pathway
0.6 25.6 PID IL6 7 PATHWAY IL6-mediated signaling events
0.6 42.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.6 15.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.6 10.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.6 13.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.6 41.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.6 13.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.6 3.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.6 7.8 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.5 20.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.5 3.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.5 8.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.4 17.8 PID P53 REGULATION PATHWAY p53 pathway
0.4 28.2 PID E2F PATHWAY E2F transcription factor network
0.4 7.4 PID ALK2 PATHWAY ALK2 signaling events
0.4 12.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.4 14.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.3 8.9 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.3 6.8 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.3 11.8 PID IL12 2PATHWAY IL12-mediated signaling events
0.3 3.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.3 5.7 PID INSULIN PATHWAY Insulin Pathway
0.3 5.0 PID IL1 PATHWAY IL1-mediated signaling events
0.3 4.7 PID FAS PATHWAY FAS (CD95) signaling pathway
0.3 7.5 PID TRAIL PATHWAY TRAIL signaling pathway
0.2 9.1 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.2 17.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.2 7.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.2 6.8 PID LKB1 PATHWAY LKB1 signaling events
0.2 22.1 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.2 5.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.1 6.7 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 6.9 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 4.8 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 1.7 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 1.0 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 1.3 PID ARF6 PATHWAY Arf6 signaling events
0.1 2.2 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 0.2 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.1 1.5 PID AURORA B PATHWAY Aurora B signaling
0.0 1.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.7 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.1 PID ERBB4 PATHWAY ErbB4 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
7.1 169.5 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
5.8 29.0 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
5.5 65.5 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
4.5 57.9 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
4.1 57.7 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
4.1 85.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
3.7 70.0 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
3.7 124.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
3.6 271.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
3.5 186.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
3.5 62.6 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
3.2 419.0 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
3.1 40.6 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
3.1 205.9 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
3.0 132.6 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
3.0 65.7 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
2.7 253.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
2.7 24.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
2.5 37.9 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
2.3 9.4 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
2.3 27.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
2.2 49.1 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
2.2 73.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
2.2 52.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
2.1 41.3 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
2.1 135.8 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
2.0 32.8 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
2.0 88.0 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
1.9 61.8 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
1.9 11.5 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
1.9 57.7 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
1.9 39.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
1.9 26.0 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
1.8 29.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
1.8 27.5 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
1.8 16.3 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
1.8 32.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
1.8 19.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
1.8 40.8 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
1.7 47.1 REACTOME TRANSLATION Genes involved in Translation
1.7 29.5 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
1.7 15.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
1.7 34.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
1.7 111.7 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
1.6 61.6 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
1.6 174.0 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
1.4 19.9 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
1.4 44.7 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
1.3 16.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
1.3 9.2 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
1.3 21.9 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
1.3 60.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
1.2 17.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
1.2 30.8 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
1.2 8.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
1.2 15.6 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
1.2 35.4 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
1.2 29.1 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
1.1 22.6 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
1.1 50.5 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
1.1 25.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
1.1 19.7 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
1.1 37.4 REACTOME G1 PHASE Genes involved in G1 Phase
1.0 20.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
1.0 83.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.9 7.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.9 27.1 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.9 3.6 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.9 21.8 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.9 5.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.8 45.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.8 19.4 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.8 23.1 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.8 16.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.8 15.3 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.7 11.2 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.7 11.9 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.7 110.9 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.7 14.4 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.7 8.8 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.7 25.3 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.7 56.6 REACTOME MYD88 MAL CASCADE INITIATED ON PLASMA MEMBRANE Genes involved in MyD88:Mal cascade initiated on plasma membrane
0.6 15.2 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.6 19.4 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.6 6.7 REACTOME TCR SIGNALING Genes involved in TCR signaling
0.5 15.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.5 10.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.5 10.6 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.5 24.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.4 32.0 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.4 18.3 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.4 4.8 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.3 9.0 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.3 15.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.3 3.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.3 4.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.2 30.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.2 1.4 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.2 9.9 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.2 1.3 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.2 3.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.2 4.0 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.2 6.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.2 1.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.2 1.3 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.2 3.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 1.6 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 2.7 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.1 0.6 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 5.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.8 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 0.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.1 1.9 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.1 1.6 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 1.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 1.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 1.0 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction