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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ETV1_ERF_FEV_ELF1

Z-value: 3.74

Motif logo

Transcription factors associated with ETV1_ERF_FEV_ELF1

Gene Symbol Gene ID Gene Info
ENSG00000006468.14 ETV1
ENSG00000105722.10 ERF
ENSG00000163497.3 FEV
ENSG00000120690.16 ELF1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ELF1hg38_v1_chr13_-_41019289_41019343-0.712.7e-35Click!
ERFhg38_v1_chr19_-_42255119_422551370.267.6e-05Click!
ETV1hg38_v1_chr7_-_13988863_139888910.212.0e-03Click!
FEVhg38_v1_chr2_-_218985176_218985205-0.018.6e-01Click!

Activity profile of ETV1_ERF_FEV_ELF1 motif

Sorted Z-values of ETV1_ERF_FEV_ELF1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ETV1_ERF_FEV_ELF1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr1_-_169367746 68.45 ENST00000367811.8
ENST00000472647.5
NME/NM23 family member 7
chr5_+_892844 59.31 ENST00000166345.8
thyroid hormone receptor interactor 13
chr2_+_176269406 58.69 ENST00000249442.11
ENST00000443241.5
metaxin 2
chr5_-_140691312 57.99 ENST00000438307.6
ENST00000415192.6
ENST00000509087.2
ENST00000675698.1
ENST00000504156.7
ENST00000457527.6
ENST00000307633.7
ENST00000676327.1
ENST00000675851.1
ENST00000675366.1
ENST00000675204.1
ENST00000507746.7
ENST00000431330.7
histidyl-tRNA synthetase 1
chr15_+_90265634 54.68 ENST00000379095.5
neugrin, neurite outgrowth associated
chr2_+_176269473 53.31 ENST00000452865.1
metaxin 2
chr1_-_1375490 50.89 ENST00000338338.9
aurora kinase A interacting protein 1
chr14_-_69398276 45.55 ENST00000557016.6
ENST00000555373.1
ERH mRNA splicing and mitosis factor
chr10_-_15860450 43.39 ENST00000277632.8
MINDY lysine 48 deubiquitinase 3
chr1_-_1375150 42.98 ENST00000338370.7
ENST00000321751.9
ENST00000378853.3
aurora kinase A interacting protein 1
chr5_+_69234795 42.93 ENST00000626796.2
ENST00000629350.2
ENST00000506563.5
ENST00000256443.8
ENST00000514676.5
cyclin dependent kinase 7
chr11_+_119018746 42.84 ENST00000528230.5
ENST00000525303.5
ENST00000434101.6
ENST00000359005.8
ENST00000533632.6
ENST00000533058.5
trafficking protein particle complex 4
chr1_-_43172504 41.98 ENST00000431635.6
EBNA1 binding protein 2
chr8_-_120445092 40.44 ENST00000518918.1
mitochondrial ribosomal protein L13
chr11_-_46700567 40.03 ENST00000311956.9
Rho GTPase activating protein 1
chr8_+_144078661 40.01 ENST00000316052.6
exosome component 4
chr11_+_70398404 39.57 ENST00000346329.7
ENST00000301843.13
ENST00000376561.7
cortactin
chr8_-_120445140 38.72 ENST00000306185.8
mitochondrial ribosomal protein L13
chr8_+_144078590 38.11 ENST00000525936.1
exosome component 4
chr17_-_59707404 37.83 ENST00000393038.3
peptidyl-tRNA hydrolase 2
chr1_-_43172244 37.54 ENST00000236051.3
EBNA1 binding protein 2
chr12_+_56152579 37.39 ENST00000551834.5
ENST00000552568.5
myosin light chain 6B
chr16_-_20806431 37.38 ENST00000357967.9
ENST00000300005.7
ENST00000569729.5
ERI1 exoribonuclease family member 2
chr2_-_73737320 37.32 ENST00000272424.11
TP53RK binding protein
chr20_+_31739260 37.24 ENST00000340513.4
ENST00000300403.11
TPX2 microtubule nucleation factor
chr8_+_30442602 36.09 ENST00000520191.5
RNA binding protein, mRNA processing factor
chr1_+_169368175 34.44 ENST00000367808.8
ENST00000426663.1
basic leucine zipper nuclear factor 1
chrX_+_51803007 34.41 ENST00000375772.7
MAGE family member D1
chr2_-_109614143 34.34 ENST00000356688.8
septin 10
chr11_-_116787979 34.32 ENST00000429220.5
ENST00000444935.5
ENST00000227322.8
ZPR1 zinc finger
chr2_-_73737374 34.11 ENST00000318190.7
ENST00000409716.6
TP53RK binding protein
chr2_-_109613835 34.05 ENST00000415095.5
ENST00000437928.5
ENST00000493445.5
ENST00000397714.6
ENST00000461295.1
ENST00000397712.7
septin 10
chr20_-_56392131 33.29 ENST00000422322.5
ENST00000371356.6
ENST00000451915.1
ENST00000347343.6
ENST00000395911.5
ENST00000395915.8
ENST00000395907.5
ENST00000441357.5
ENST00000456249.5
ENST00000420474.5
ENST00000395914.5
ENST00000312783.10
ENST00000395913.7
aurora kinase A
chr1_+_154974653 33.00 ENST00000368439.5
CDC28 protein kinase regulatory subunit 1B
chr12_+_56152439 32.75 ENST00000550443.5
myosin light chain 6B
chr5_+_132866624 32.07 ENST00000378667.1
ENST00000378670.8
ENST00000378665.1
ubiquinol-cytochrome c reductase complex III subunit VII
chr3_-_57597443 31.88 ENST00000463880.1
ADP ribosylation factor 4
chr10_+_87504867 31.82 ENST00000371994.8
multiple inositol-polyphosphate phosphatase 1
chr2_+_200889327 31.80 ENST00000426253.5
ENST00000454952.1
ENST00000651500.1
ENST00000409020.6
ENST00000359683.8
NGG1 interacting factor 3 like 1
chr7_+_128739395 31.71 ENST00000479257.5
calumenin
chr7_+_128739292 31.65 ENST00000535011.6
ENST00000542996.6
ENST00000249364.9
ENST00000449187.6
calumenin
chr21_+_17513003 30.61 ENST00000284878.12
ENST00000400166.5
CXADR Ig-like cell adhesion molecule
chr10_+_87504885 30.49 ENST00000371996.9
multiple inositol-polyphosphate phosphatase 1
chr2_+_200889411 30.31 ENST00000409357.5
ENST00000409129.2
NGG1 interacting factor 3 like 1
chr16_-_31074193 30.00 ENST00000300849.5
zinc finger protein 668
chr6_+_33289650 29.93 ENST00000463584.1
prefoldin subunit 6
chr20_-_50958520 29.89 ENST00000371588.10
ENST00000371584.9
ENST00000413082.1
ENST00000371582.8
dolichyl-phosphate mannosyltransferase subunit 1, catalytic
chr20_+_44475867 29.64 ENST00000262605.9
ENST00000372904.7
ENST00000372906.2
ENST00000456317.1
alpha tocopherol transfer protein like
chr12_-_110450298 29.58 ENST00000426440.5
ENST00000228825.12
actin related protein 2/3 complex subunit 3
chr21_-_32612577 29.49 ENST00000673985.1
ENST00000382549.8
CFAP298-TCP10L readthrough
cilia and flagella associated protein 298
chr17_+_7583828 29.10 ENST00000396501.8
ENST00000250124.11
ENST00000584378.5
ENST00000423172.6
ENST00000579445.5
ENST00000585217.5
ENST00000581380.1
mannose-P-dolichol utilization defect 1
chr6_+_33289569 28.72 ENST00000374610.6
ENST00000374607.5
ENST00000374606.10
prefoldin subunit 6
chr21_-_25734887 28.68 ENST00000400094.5
ENST00000284971.8
ATP synthase peripheral stalk subunit F6
chr12_+_6724008 28.02 ENST00000626119.2
ENST00000543155.6
COP9 signalosome subunit 7A
chr15_+_63048535 27.99 ENST00000560959.5
tropomyosin 1
chr1_-_246566238 27.73 ENST00000366514.5
transcription factor B2, mitochondrial
chr9_+_33265013 27.70 ENST00000223500.9
charged multivesicular body protein 5
chr21_-_25735026 27.29 ENST00000400099.5
ENST00000457143.6
ATP synthase peripheral stalk subunit F6
chr3_-_48440022 27.02 ENST00000447018.5
ENST00000442740.1
ENST00000412398.6
ENST00000395694.7
coiled-coil domain containing 51
chr3_-_28348805 27.00 ENST00000457172.5
ENST00000479665.6
5-azacytidine induced 2
chr14_+_69398683 26.88 ENST00000556605.5
ENST00000031146.8
ENST00000336643.10
solute carrier family 39 member 9
chr11_+_46701010 26.81 ENST00000311764.3
zinc finger protein 408
chr11_-_31804067 26.79 ENST00000639548.1
ENST00000640125.1
ENST00000481563.6
ENST00000639079.1
ENST00000638762.1
ENST00000638346.1
paired box 6
chr2_-_9423340 26.67 ENST00000484735.5
ENST00000456913.6
integrin subunit beta 1 binding protein 1
chr1_-_37989978 26.37 ENST00000373019.5
splicing factor 3a subunit 3
chr17_-_67366562 26.35 ENST00000356126.8
ENST00000357146.4
proteasome 26S subunit, non-ATPase 12
chr16_+_67227105 26.30 ENST00000563953.5
ENST00000304800.14
ENST00000565201.1
transmembrane protein 208
chr9_+_33264848 26.27 ENST00000419016.6
charged multivesicular body protein 5
chrX_-_40735476 26.27 ENST00000324817.6
mediator complex subunit 14
chr6_-_31958935 26.16 ENST00000441998.5
ENST00000444811.6
ENST00000375429.8
negative elongation factor complex member E
chr11_+_74171266 26.02 ENST00000328257.13
ENST00000398427.6
protein phosphatase methylesterase 1
chr7_-_2242164 26.02 ENST00000242257.14
mitochondrial rRNA methyltransferase 2
chr14_+_75002903 25.97 ENST00000266126.10
eukaryotic translation initiation factor 2B subunit beta
chr1_+_38012706 25.91 ENST00000373014.5
UTP11 small subunit processome component
chr5_+_103120149 25.79 ENST00000515845.5
ENST00000321521.13
ENST00000507921.5
diphosphoinositol pentakisphosphate kinase 2
chr1_-_43389768 25.66 ENST00000372455.4
ENST00000372457.9
ENST00000290663.10
mediator complex subunit 8
chr19_+_16185380 25.28 ENST00000589852.5
ENST00000263384.12
ENST00000588367.5
ENST00000587351.1
family with sequence similarity 32 member A
chr7_-_7640971 25.21 ENST00000396682.6
replication protein A3
chr5_+_140691591 25.20 ENST00000508522.5
ENST00000448069.2
histidyl-tRNA synthetase 2, mitochondrial
chr3_+_57556244 24.85 ENST00000311180.9
ENST00000487257.1
phosphodiesterase 12
chr15_+_63048658 24.81 ENST00000560615.5
ENST00000651577.1
tropomyosin 1
chr7_-_5513738 24.74 ENST00000453700.7
ENST00000382368.8
F-box and leucine rich repeat protein 18
chr11_-_6481350 24.57 ENST00000423813.6
ENST00000614314.4
ADP ribosylation factor interacting protein 2
chr14_+_90256542 24.52 ENST00000261303.13
ENST00000543772.2
proteasome 26S subunit, ATPase 1
chr17_+_42833390 24.50 ENST00000590720.6
ENST00000586114.5
ENST00000585805.5
ENST00000441946.6
ENST00000591152.5
ENST00000589469.5
ENST00000293362.7
ENST00000592169.2
proteasome activator subunit 3
chr7_+_44200960 24.13 ENST00000496112.5
ENST00000678359.1
ENST00000223369.3
ENST00000677090.1
YKT6 v-SNARE homolog
chr11_-_6481304 24.07 ENST00000254584.6
ENST00000525235.1
ENST00000396777.8
ENST00000445086.6
ADP ribosylation factor interacting protein 2
chr14_-_67359769 23.99 ENST00000555431.5
ENST00000554236.5
ENST00000555474.5
ENST00000216442.12
ATPase H+ transporting V1 subunit D
chr5_+_103120264 23.55 ENST00000358359.8
diphosphoinositol pentakisphosphate kinase 2
chr21_-_32612339 23.53 ENST00000440966.5
ENST00000290155.8
cilia and flagella associated protein 298
chr6_-_31958852 23.44 ENST00000375425.9
ENST00000426722.5
negative elongation factor complex member E
chr7_+_2242256 23.31 ENST00000397046.5
ENST00000397048.5
ENST00000454650.1
nudix hydrolase 1
chr12_+_6724071 23.29 ENST00000229251.7
ENST00000539735.5
ENST00000538410.5
COP9 signalosome subunit 7A
chr6_+_33391805 23.22 ENST00000428849.7
ENST00000450504.1
kinesin family member C1
chr4_+_41990496 22.90 ENST00000264451.12
solute carrier family 30 member 9
chr12_+_6724271 22.66 ENST00000534947.5
ENST00000541866.5
ENST00000534877.5
ENST00000538753.5
COP9 signalosome subunit 7A
chr7_+_99325857 22.64 ENST00000638617.1
ENST00000262942.10
novel protein, ARPC1A and ARPC1B readthrough
actin related protein 2/3 complex subunit 1A
chr17_-_4940023 22.62 ENST00000225665.12
ENST00000544061.6
solute carrier family 25 member 11
chr20_+_16729961 22.62 ENST00000377943.9
ENST00000246071.8
small nuclear ribonucleoprotein polypeptide B2
chr7_+_103347635 22.40 ENST00000679250.1
ENST00000292644.5
ENST00000425206.6
proteasome 26S subunit, ATPase 2
chr5_+_134648772 22.30 ENST00000398844.7
ENST00000322887.8
SEC24 homolog A, COPII coat complex component
chr1_-_165768835 22.30 ENST00000481278.5
transmembrane and coiled-coil domains 1
chr11_-_64245816 22.28 ENST00000542235.1
protein phosphatase 1 regulatory inhibitor subunit 14B
chr7_+_101218146 22.26 ENST00000305105.3
zinc finger HIT-type containing 1
chr1_+_32222393 22.25 ENST00000676679.1
ENST00000678689.1
ENST00000373586.2
ENST00000679290.1
ENST00000677378.1
ENST00000678534.1
ENST00000678968.1
ENST00000678063.1
ENST00000678150.1
ENST00000677198.1
ENST00000677540.1
eukaryotic translation initiation factor 3 subunit I
chrX_+_70290077 22.18 ENST00000374403.4
kinesin family member 4A
chr16_-_66934362 22.18 ENST00000567511.1
ENST00000422424.7
cytosolic iron-sulfur assembly component 2B
chr17_+_35587478 21.99 ENST00000618940.4
adaptor related protein complex 2 subunit beta 1
chr3_+_130893959 21.93 ENST00000508532.5
ENST00000533801.6
ATPase secretory pathway Ca2+ transporting 1
chr7_+_99408609 21.52 ENST00000403633.6
BUD31 homolog
chr1_-_959240 21.48 ENST00000327044.7
NOC2 like nucleolar associated transcriptional repressor
chr8_-_38176674 21.47 ENST00000520755.5
LSM1 homolog, mRNA degradation associated
chr14_-_24232332 21.43 ENST00000534348.5
ENST00000524927.1
ENST00000250495.10
NEDD8-MDP1 readthrough
NEDD8 ubiquitin like modifier
chr6_-_31652678 21.30 ENST00000437771.5
ENST00000362049.10
ENST00000439687.6
ENST00000211379.9
ENST00000375964.11
ENST00000676571.1
ENST00000676615.1
BAG cochaperone 6
chr8_-_77000194 21.25 ENST00000522527.5
peroxisomal biogenesis factor 2
chr10_+_73744346 21.24 ENST00000345254.9
ENST00000339365.2
SEC24 homolog C, COPII coat complex component
chr1_-_26890237 21.20 ENST00000431781.2
ENST00000374135.9
GPN-loop GTPase 2
chr3_+_130894157 21.19 ENST00000504948.5
ENST00000513801.5
ENST00000505072.5
ATPase secretory pathway Ca2+ transporting 1
chr7_-_99408548 21.17 ENST00000626285.1
ENST00000350498.8
PDGFA associated protein 1
chr1_+_32222415 21.08 ENST00000678420.1
ENST00000678162.1
ENST00000678711.1
ENST00000678883.1
ENST00000677353.1
ENST00000355082.10
eukaryotic translation initiation factor 3 subunit I
chr18_-_812516 21.03 ENST00000584307.5
YES proto-oncogene 1, Src family tyrosine kinase
chr16_+_20806698 20.98 ENST00000564274.5
ENST00000563068.1
RNA exonuclease 5
chr3_-_186806445 20.95 ENST00000418288.5
ENST00000296273.7
replication factor C subunit 4
chr3_+_130894050 20.93 ENST00000510168.6
ATPase secretory pathway Ca2+ transporting 1
chr11_+_9384621 20.93 ENST00000379719.8
ENST00000527431.1
ENST00000630083.1
importin 7
chr5_+_126423176 20.77 ENST00000542322.5
ENST00000544396.5
GRAM domain containing 2B
chr9_+_111631354 20.74 ENST00000374294.3
DNAJC25-GNG10 readthrough
chr3_-_131502946 20.72 ENST00000512877.1
ENST00000264995.8
ENST00000511168.5
ENST00000425847.6
mitochondrial ribosomal protein L3
chr19_-_55280194 20.62 ENST00000588971.1
ENST00000255631.9
ENST00000587551.1
HSPA (Hsp70) binding protein 1
chr5_+_95731300 20.59 ENST00000379982.8
Rho related BTB domain containing 3
chr7_+_39623547 20.57 ENST00000005257.7
RAS like proto-oncogene A
chr17_+_75012659 20.44 ENST00000584208.5
ENST00000301585.10
mitochondrial ribosomal protein L58
chr3_+_130894382 20.34 ENST00000509662.5
ENST00000328560.12
ENST00000428331.6
ENST00000359644.7
ENST00000422190.6
ATPase secretory pathway Ca2+ transporting 1
chr16_+_20806517 20.31 ENST00000348433.10
ENST00000568501.5
ENST00000261377.11
ENST00000566276.5
RNA exonuclease 5
chr8_-_38176441 20.15 ENST00000311351.9
LSM1 homolog, mRNA degradation associated
chr11_-_65888435 20.12 ENST00000357519.9
ENST00000533045.5
ENST00000338369.6
FGF1 intracellular binding protein
chr16_-_47461039 19.81 ENST00000320640.11
integrin alpha FG-GAP repeat containing 1
chr7_+_2242207 19.68 ENST00000356714.6
nudix hydrolase 1
chr5_+_141359970 19.64 ENST00000522605.2
ENST00000622527.1
protocadherin gamma subfamily B, 2
chrX_+_30215551 19.62 ENST00000378988.5
MAGE family member B2
chr5_+_83077559 19.61 ENST00000511817.1
X-ray repair cross complementing 4
chr11_+_6481473 19.56 ENST00000530751.1
ENST00000254616.11
translocase of inner mitochondrial membrane 10B
chr5_+_126423363 19.47 ENST00000285689.8
GRAM domain containing 2B
chr7_+_99408958 19.43 ENST00000222969.10
BUD31 homolog
chr19_-_55280063 19.38 ENST00000593263.5
ENST00000433386.7
HSPA (Hsp70) binding protein 1
chr9_-_35103178 19.34 ENST00000452248.6
ENST00000619795.4
stomatin like 2
chr5_+_83077498 19.32 ENST00000282268.7
ENST00000338635.10
ENST00000396027.9
X-ray repair cross complementing 4
chr16_+_56451513 19.31 ENST00000562150.5
ENST00000561646.5
ENST00000566157.6
ENST00000568397.1
2-oxoglutarate and iron dependent oxygenase domain containing 1
chr20_-_45857196 19.26 ENST00000457981.5
ENST00000426915.1
ENST00000217455.9
acyl-CoA thioesterase 8
chrX_+_11111291 19.21 ENST00000321143.8
ENST00000380762.5
ENST00000380763.7
holocytochrome c synthase
chr16_-_66934144 19.10 ENST00000568572.5
cytosolic iron-sulfur assembly component 2B
chr17_+_7252237 19.07 ENST00000570500.5
elongator acetyltransferase complex subunit 5
chrX_+_100820359 19.04 ENST00000415585.6
ENST00000372972.7
ENST00000413437.1
cleavage stimulation factor subunit 2
chr9_-_35103108 18.94 ENST00000356493.10
stomatin like 2
chr14_+_93184951 18.87 ENST00000283534.4
ENST00000557574.1
transmembrane protein 251
novel protein
chr14_+_77457861 18.87 ENST00000555133.5
activator of HSP90 ATPase activity 1
chr11_-_18526885 18.71 ENST00000251968.4
ENST00000536719.5
tumor susceptibility 101
chr9_-_124415421 18.60 ENST00000259457.8
ENST00000441097.1
proteasome 20S subunit beta 7
chr16_-_47461259 18.51 ENST00000544001.6
integrin alpha FG-GAP repeat containing 1
chr15_+_63048436 18.48 ENST00000334895.10
ENST00000404484.9
ENST00000558910.3
ENST00000317516.12
tropomyosin 1
chr5_+_126423122 18.45 ENST00000515200.5
GRAM domain containing 2B
chr10_+_49942048 18.41 ENST00000651259.3
ENST00000652716.1
translocase of inner mitochondrial membrane 23 homolog B
chr2_-_9423190 18.37 ENST00000497105.1
ENST00000360635.7
ENST00000359712.7
integrin subunit beta 1 binding protein 1
chr10_+_45972482 18.37 ENST00000580018.4
translocase of inner mitochondrial membrane 23
chr20_-_49915509 18.24 ENST00000289431.10
spermatogenesis associated 2
chr7_-_44490609 18.22 ENST00000355451.8
NudC domain containing 3
chr3_-_100401028 18.21 ENST00000284320.6
translocase of outer mitochondrial membrane 70
chr22_+_39502237 18.14 ENST00000325301.7
mitochondrial elongation factor 1
chr1_+_218285283 18.08 ENST00000366932.4
ribosomal RNA processing 15 homolog
chr8_-_73972248 18.07 ENST00000519082.5
elongin C
chr19_+_19516216 17.91 ENST00000507754.9
ENST00000503283.5
ENST00000428459.6
ENST00000555938.1
NADH:ubiquinone oxidoreductase subunit A13
novel protein
chr12_-_105236074 17.88 ENST00000551662.5
ENST00000553097.5
ENST00000258530.8
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
chr2_+_27663880 17.56 ENST00000618046.4
ENST00000613517.4
solute carrier family 4 member 1 adaptor protein
chr1_-_200620729 17.47 ENST00000367350.5
kinesin family member 14
chr19_+_9827886 17.43 ENST00000358666.7
ENST00000590068.1
ENST00000593087.1
ENST00000586895.6
ubiquitin like 5
chr14_-_57268810 17.39 ENST00000413566.6
ENST00000340918.11
ENST00000621441.5
exocyst complex component 5
chr3_+_100709290 17.23 ENST00000675047.1
ENST00000490574.6
ENST00000675543.1
ENST00000676308.1
ENST00000675499.1
trafficking from ER to golgi regulator
chr12_+_56224318 17.18 ENST00000267023.9
ENST00000380198.6
ENST00000341463.5
nucleic acid binding protein 2
chr3_-_64023424 17.13 ENST00000478185.1
ENST00000482510.5
ENST00000497323.5
ENST00000492933.5
ENST00000295901.9
proteasome 26S subunit, non-ATPase 6
chr15_-_70892412 17.13 ENST00000249861.9
THAP domain containing 10
chr6_-_33271835 17.07 ENST00000482399.5
ENST00000445902.3
VPS52 subunit of GARP complex
chr6_-_43013913 17.07 ENST00000244711.4
ENST00000643776.1
male-enhanced antigen 1
chr22_+_39502320 16.92 ENST00000404569.5
mitochondrial elongation factor 1
chr1_-_110963936 16.88 ENST00000485275.2
ligand dependent nuclear receptor interacting factor 1
chr1_-_160343235 16.84 ENST00000368069.7
ENST00000241704.8
ENST00000647683.1
ENST00000649787.1
COPI coat complex subunit alpha
chr9_+_130579556 16.82 ENST00000319725.10
far upstream element binding protein 3
chr1_-_85276467 16.76 ENST00000648566.1
BCL10 immune signaling adaptor
chr9_-_33264559 16.73 ENST00000473781.1
ENST00000379704.7
ENST00000488499.1
BAG cochaperone 1
chr17_+_7252502 16.52 ENST00000570322.5
ENST00000576496.5
ENST00000574841.2
elongator acetyltransferase complex subunit 5
chr3_+_143001562 16.36 ENST00000473835.7
ENST00000493598.6
U2 snRNP associated SURP domain containing
chr8_-_73972223 16.34 ENST00000522337.5
elongin C
chr17_+_7252268 16.20 ENST00000396628.6
ENST00000574993.5
ENST00000573657.5
elongator acetyltransferase complex subunit 5
chr1_-_165768848 16.20 ENST00000367881.11
ENST00000464650.5
ENST00000612311.4
ENST00000628579.1
transmembrane and coiled-coil domains 1
chr7_+_101127095 16.18 ENST00000223095.5
serpin family E member 1
chr17_-_42017410 16.13 ENST00000316603.12
ENST00000674175.1
ENST00000674233.1
ENST00000457167.9
ENST00000674306.1
DnaJ heat shock protein family (Hsp40) member C7
chr6_-_32176051 16.11 ENST00000375107.8
1-acylglycerol-3-phosphate O-acyltransferase 1
chr20_-_35699317 15.95 ENST00000397425.5
ENST00000374092.9
ENST00000541387.5
NFS1 cysteine desulfurase
chr1_-_110963897 15.90 ENST00000369763.5
ligand dependent nuclear receptor interacting factor 1
chr3_-_9986682 15.84 ENST00000429759.5
ER membrane protein complex subunit 3
chr17_+_59707636 15.81 ENST00000262291.9
ENST00000587945.1
ENST00000589823.6
ENST00000592106.5
ENST00000591315.5
vacuole membrane protein 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
16.9 84.7 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
16.9 84.5 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
15.4 15.4 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
15.2 45.5 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
14.2 42.7 GO:0035048 splicing factor protein import into nucleus(GO:0035048)
14.1 84.4 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
13.4 40.2 GO:0070650 endoplasmic reticulum polarization(GO:0061163) actin filament bundle retrograde transport(GO:0061573) actin filament bundle distribution(GO:0070650)
12.8 38.3 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
11.8 35.3 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
10.2 50.8 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
10.0 30.1 GO:0018283 metal incorporation into metallo-sulfur cluster(GO:0018282) iron incorporation into metallo-sulfur cluster(GO:0018283)
10.0 30.1 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
9.5 28.6 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
9.2 27.7 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
8.4 25.2 GO:0044565 dendritic cell proliferation(GO:0044565)
8.0 32.1 GO:0021539 subthalamus development(GO:0021539)
7.8 62.2 GO:0007144 female meiosis I(GO:0007144)
7.7 23.2 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
7.7 30.6 GO:0098904 regulation of AV node cell action potential(GO:0098904)
7.6 38.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
7.5 22.6 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
7.4 37.2 GO:1904579 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
7.4 36.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
7.1 35.7 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
7.1 21.2 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
6.9 34.3 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
6.8 20.3 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
6.7 26.7 GO:0046203 spermidine catabolic process(GO:0046203)
6.3 94.6 GO:0000338 protein deneddylation(GO:0000338)
6.3 31.5 GO:0019348 dolichol metabolic process(GO:0019348)
6.3 31.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
6.2 18.7 GO:2000397 ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
6.0 18.1 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
6.0 18.0 GO:0002184 cytoplasmic translational termination(GO:0002184)
5.9 17.8 GO:1904732 regulation of electron carrier activity(GO:1904732)
5.9 23.7 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
5.7 28.5 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
5.6 16.8 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
5.5 22.1 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
5.4 37.8 GO:0032218 riboflavin transport(GO:0032218)
5.4 16.2 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
5.4 21.5 GO:2000232 regulation of rRNA processing(GO:2000232)
5.4 43.0 GO:0046061 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
5.2 15.7 GO:0030327 prenylated protein catabolic process(GO:0030327)
5.1 35.6 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
5.0 15.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
4.8 19.2 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
4.7 47.4 GO:0045176 apical protein localization(GO:0045176)
4.7 37.8 GO:2000210 positive regulation of anoikis(GO:2000210)
4.6 91.5 GO:0006228 UTP biosynthetic process(GO:0006228)
4.5 13.6 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
4.5 22.6 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
4.5 49.7 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
4.4 17.8 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
4.4 26.5 GO:0051030 snRNA transport(GO:0051030)
4.4 22.1 GO:0090034 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
4.4 13.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
4.4 8.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
4.4 17.5 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
4.4 21.8 GO:0019323 pentose catabolic process(GO:0019323)
4.3 73.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
4.3 12.8 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
4.2 84.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
4.2 63.1 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
4.2 88.1 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
4.0 64.8 GO:0043248 proteasome assembly(GO:0043248)
3.9 35.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
3.9 296.4 GO:0070125 mitochondrial translational elongation(GO:0070125)
3.9 11.6 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
3.9 34.8 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
3.9 11.6 GO:0097498 endothelial tube lumen extension(GO:0097498)
3.8 22.8 GO:1904274 tricellular tight junction assembly(GO:1904274)
3.8 30.3 GO:0002084 protein depalmitoylation(GO:0002084)
3.8 30.2 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
3.7 11.0 GO:2000847 negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
3.6 25.3 GO:0070294 renal sodium ion absorption(GO:0070294)
3.6 21.7 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
3.6 39.6 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
3.6 106.7 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
3.6 10.7 GO:0007174 epidermal growth factor catabolic process(GO:0007174)
3.5 14.2 GO:0051182 coenzyme transport(GO:0051182)
3.4 10.3 GO:0060296 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
3.4 30.7 GO:0033182 regulation of histone ubiquitination(GO:0033182)
3.4 53.9 GO:0006020 inositol metabolic process(GO:0006020)
3.4 53.6 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
3.3 76.3 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
3.3 9.9 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
3.2 29.1 GO:2000580 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
3.2 51.4 GO:0045116 protein neddylation(GO:0045116)
3.2 51.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
3.2 47.3 GO:0006983 ER overload response(GO:0006983)
3.1 15.4 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
3.0 36.3 GO:1904869 regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
3.0 18.1 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
3.0 18.1 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
3.0 9.0 GO:1902309 regulation of heart rate by hormone(GO:0003064) negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
3.0 116.4 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
3.0 3.0 GO:0045048 protein insertion into ER membrane(GO:0045048)
2.9 14.7 GO:0051036 regulation of endosome size(GO:0051036)
2.9 8.7 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
2.9 17.4 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
2.9 2.9 GO:0000963 mitochondrial RNA processing(GO:0000963)
2.8 48.0 GO:0003322 pancreatic A cell development(GO:0003322)
2.7 24.7 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
2.7 24.7 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
2.7 30.1 GO:0051665 membrane raft localization(GO:0051665)
2.7 24.5 GO:0016559 peroxisome fission(GO:0016559)
2.7 8.1 GO:1901899 positive regulation of relaxation of cardiac muscle(GO:1901899)
2.7 21.5 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
2.6 18.5 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
2.6 18.5 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
2.6 18.3 GO:0015677 copper ion import(GO:0015677)
2.6 41.8 GO:0070987 error-free translesion synthesis(GO:0070987)
2.5 10.2 GO:0000961 negative regulation of mitochondrial RNA catabolic process(GO:0000961)
2.5 2.5 GO:1901355 response to rapamycin(GO:1901355)
2.5 17.5 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
2.5 9.9 GO:0030047 actin modification(GO:0030047)
2.5 7.4 GO:0060166 olfactory pit development(GO:0060166)
2.5 7.4 GO:2000653 regulation of genetic imprinting(GO:2000653)
2.5 17.2 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
2.4 9.8 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
2.4 2.4 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
2.4 2.4 GO:0046070 dGTP metabolic process(GO:0046070)
2.4 11.9 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
2.4 16.6 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
2.3 44.1 GO:0075713 establishment of integrated proviral latency(GO:0075713)
2.3 61.9 GO:0006829 zinc II ion transport(GO:0006829)
2.2 2.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
2.2 4.5 GO:0072244 metanephric glomerular epithelium development(GO:0072244) metanephric glomerular visceral epithelial cell differentiation(GO:0072248) metanephric glomerular visceral epithelial cell development(GO:0072249) metanephric glomerular epithelial cell differentiation(GO:0072312) metanephric glomerular epithelial cell development(GO:0072313)
2.2 4.4 GO:1903233 regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
2.2 6.6 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
2.2 4.4 GO:0019249 lactate biosynthetic process(GO:0019249)
2.2 8.7 GO:0002188 translation reinitiation(GO:0002188)
2.2 175.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
2.2 4.3 GO:0007007 inner mitochondrial membrane organization(GO:0007007)
2.1 23.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
2.1 12.8 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
2.1 36.2 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
2.1 6.3 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
2.1 12.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
2.1 35.2 GO:0034389 lipid particle organization(GO:0034389)
2.1 6.2 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
2.1 10.3 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
2.0 10.1 GO:0016080 synaptic vesicle targeting(GO:0016080)
2.0 48.5 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
2.0 6.0 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
2.0 29.8 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
2.0 6.0 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
2.0 11.9 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
2.0 13.7 GO:0036258 multivesicular body assembly(GO:0036258)
2.0 7.8 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
1.9 7.8 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
1.9 7.8 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
1.9 5.8 GO:0051821 negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010768) transmission of virus(GO:0019089) dissemination or transmission of symbiont from host(GO:0044007) development involved in symbiotic interaction(GO:0044111) dissemination or transmission of organism from other organism involved in symbiotic interaction(GO:0051821)
1.9 71.3 GO:0007080 mitotic metaphase plate congression(GO:0007080)
1.9 13.5 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
1.9 9.5 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
1.9 13.3 GO:0000012 single strand break repair(GO:0000012)
1.9 7.4 GO:0072319 synaptic vesicle uncoating(GO:0016191) vesicle uncoating(GO:0072319)
1.9 3.7 GO:0006447 regulation of translational initiation by iron(GO:0006447)
1.9 16.7 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
1.8 5.5 GO:1903565 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
1.8 3.7 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
1.8 16.4 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
1.8 7.3 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
1.8 23.6 GO:0042407 cristae formation(GO:0042407)
1.8 10.9 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
1.8 9.0 GO:0097039 protein linear polyubiquitination(GO:0097039)
1.8 17.9 GO:0060717 chorion development(GO:0060717)
1.8 12.4 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
1.8 30.1 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
1.8 45.5 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
1.7 1.7 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
1.7 12.0 GO:0006662 glycerol ether metabolic process(GO:0006662)
1.7 22.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
1.7 16.9 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
1.7 52.4 GO:0090383 phagosome acidification(GO:0090383)
1.7 148.1 GO:0006903 vesicle targeting(GO:0006903)
1.7 5.0 GO:2000520 tolerance induction dependent upon immune response(GO:0002461) regulation of immunological synapse formation(GO:2000520) negative regulation of immunological synapse formation(GO:2000521)
1.7 58.0 GO:0070897 DNA-templated transcriptional preinitiation complex assembly(GO:0070897)
1.7 5.0 GO:0035437 protein retention in ER lumen(GO:0006621) maintenance of protein localization in endoplasmic reticulum(GO:0035437)
1.6 8.2 GO:0006041 glucosamine metabolic process(GO:0006041)
1.6 9.8 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
1.6 6.5 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
1.6 17.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.6 7.8 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
1.5 4.6 GO:0090669 telomerase RNA stabilization(GO:0090669)
1.5 16.9 GO:0006108 malate metabolic process(GO:0006108)
1.5 38.3 GO:0008053 mitochondrial fusion(GO:0008053)
1.5 16.8 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
1.5 4.6 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
1.5 4.5 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
1.5 27.2 GO:0000729 DNA double-strand break processing(GO:0000729)
1.5 37.7 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
1.5 9.0 GO:0033504 floor plate development(GO:0033504)
1.5 28.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
1.5 12.0 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
1.5 5.8 GO:0071418 cellular response to amine stimulus(GO:0071418)
1.5 20.4 GO:0001682 tRNA 5'-leader removal(GO:0001682)
1.4 21.7 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
1.4 15.8 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
1.4 17.2 GO:0070200 establishment of protein localization to telomere(GO:0070200)
1.4 5.7 GO:0009956 radial pattern formation(GO:0009956)
1.4 20.9 GO:0007220 Notch receptor processing(GO:0007220)
1.4 14.9 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
1.4 8.1 GO:1904874 positive regulation of telomerase RNA localization to Cajal body(GO:1904874)
1.4 25.7 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
1.3 6.7 GO:0035900 response to isolation stress(GO:0035900)
1.3 7.9 GO:0060011 Sertoli cell proliferation(GO:0060011)
1.3 10.5 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
1.3 17.1 GO:0010668 ectodermal cell differentiation(GO:0010668)
1.3 9.0 GO:0051013 microtubule severing(GO:0051013)
1.3 2.6 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
1.3 22.9 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
1.3 8.9 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
1.3 13.9 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
1.3 7.6 GO:0033088 negative regulation of immature T cell proliferation in thymus(GO:0033088)
1.3 3.8 GO:1903937 response to acrylamide(GO:1903937)
1.2 3.6 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
1.2 7.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
1.2 16.9 GO:0038003 opioid receptor signaling pathway(GO:0038003)
1.2 10.8 GO:2001169 regulation of ATP biosynthetic process(GO:2001169) positive regulation of ATP biosynthetic process(GO:2001171)
1.2 10.8 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
1.2 30.9 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
1.2 3.6 GO:0072683 T cell extravasation(GO:0072683)
1.2 4.7 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
1.2 3.5 GO:1903537 meiotic spindle elongation(GO:0051232) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
1.2 21.0 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
1.2 31.4 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
1.2 10.4 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
1.1 4.6 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
1.1 7.9 GO:0060363 cranial suture morphogenesis(GO:0060363)
1.1 2.3 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
1.1 15.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
1.1 26.6 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
1.1 8.9 GO:0015865 purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868)
1.1 7.7 GO:0042483 negative regulation of odontogenesis(GO:0042483)
1.1 7.7 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
1.1 10.9 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
1.1 3.3 GO:1990253 cellular response to leucine starvation(GO:1990253)
1.1 4.3 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
1.1 2.1 GO:0043465 fermentation(GO:0006113) regulation of fermentation(GO:0043465)
1.1 3.2 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
1.1 5.3 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
1.1 4.2 GO:0035627 ceramide transport(GO:0035627)
1.0 31.4 GO:0031648 protein destabilization(GO:0031648)
1.0 13.5 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
1.0 5.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
1.0 77.3 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
1.0 14.4 GO:0018206 peptidyl-methionine modification(GO:0018206)
1.0 6.1 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
1.0 39.2 GO:0032781 positive regulation of ATPase activity(GO:0032781)
1.0 68.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
1.0 12.9 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
1.0 4.0 GO:1900016 negative regulation of cytokine production involved in inflammatory response(GO:1900016)
1.0 14.9 GO:0070584 mitochondrion morphogenesis(GO:0070584)
1.0 20.7 GO:0000154 rRNA modification(GO:0000154)
1.0 61.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
1.0 3.9 GO:1990928 response to amino acid starvation(GO:1990928)
1.0 8.8 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
1.0 5.8 GO:1901538 DNA methylation involved in embryo development(GO:0043045) C-5 methylation of cytosine(GO:0090116) changes to DNA methylation involved in embryo development(GO:1901538)
1.0 3.9 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
1.0 5.8 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
1.0 2.9 GO:0015822 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
1.0 73.5 GO:0008033 tRNA processing(GO:0008033)
0.9 4.7 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.9 2.8 GO:0010041 response to iron(III) ion(GO:0010041)
0.9 9.3 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.9 31.7 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.9 6.5 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.9 41.5 GO:0043486 histone exchange(GO:0043486)
0.9 13.7 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.9 127.9 GO:0006626 protein targeting to mitochondrion(GO:0006626)
0.9 9.9 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.9 6.3 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.9 17.1 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.9 4.5 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.9 3.6 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.9 9.8 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.9 3.5 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) regulation of negative chemotaxis(GO:0050923)
0.9 16.8 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.9 14.2 GO:0072520 seminiferous tubule development(GO:0072520)
0.9 8.8 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.9 0.9 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.9 25.2 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.9 12.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.9 1.7 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.9 4.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.9 3.5 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.9 3.5 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.9 2.6 GO:0036071 N-glycan fucosylation(GO:0036071)
0.9 4.3 GO:0070836 caveola assembly(GO:0070836)
0.9 23.3 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.9 3.4 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.9 5.1 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.8 21.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.8 2.5 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.8 2.5 GO:0006566 threonine metabolic process(GO:0006566)
0.8 19.1 GO:0022900 electron transport chain(GO:0022900)
0.8 9.9 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.8 4.1 GO:0021553 olfactory nerve development(GO:0021553)
0.8 9.0 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.8 25.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.8 16.3 GO:0017004 cytochrome complex assembly(GO:0017004)
0.8 36.6 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.8 3.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.8 47.3 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032436)
0.8 1.5 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.8 2.3 GO:0036079 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.8 9.8 GO:0045008 depyrimidination(GO:0045008)
0.7 6.0 GO:0001878 response to yeast(GO:0001878)
0.7 5.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.7 22.1 GO:0006270 DNA replication initiation(GO:0006270)
0.7 0.7 GO:0036245 cellular response to menadione(GO:0036245)
0.7 1.4 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.7 7.9 GO:0046415 urate metabolic process(GO:0046415)
0.7 1.4 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.7 2.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.7 51.1 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.7 2.8 GO:0072093 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.7 5.5 GO:0018344 protein geranylgeranylation(GO:0018344)
0.7 7.5 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.7 3.4 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.7 6.7 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.7 3.3 GO:0051414 response to cortisol(GO:0051414)
0.7 2.6 GO:1904980 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.7 2.0 GO:0090027 negative regulation of monocyte chemotaxis(GO:0090027)
0.7 19.0 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.7 11.1 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition(GO:0051437)
0.6 3.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.6 7.1 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.6 18.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.6 3.2 GO:0003056 regulation of vascular smooth muscle contraction(GO:0003056) negative regulation of vasoconstriction(GO:0045906)
0.6 1.3 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.6 7.1 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.6 12.8 GO:0051290 protein heterotetramerization(GO:0051290)
0.6 3.8 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.6 0.6 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.6 1.9 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.6 1.9 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.6 1.9 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.6 11.9 GO:0006012 galactose metabolic process(GO:0006012)
0.6 0.6 GO:1904908 negative regulation of maintenance of sister chromatid cohesion(GO:0034092) negative regulation of maintenance of mitotic sister chromatid cohesion(GO:0034183) maintenance of mitotic sister chromatid cohesion, telomeric(GO:0099403) mitotic sister chromatid cohesion, telomeric(GO:0099404) regulation of telomeric DNA binding(GO:1904742) regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904907) negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric(GO:1904908)
0.6 7.3 GO:0015825 L-serine transport(GO:0015825)
0.6 1.8 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.6 6.7 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.6 2.4 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.6 8.3 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.6 27.1 GO:0006110 regulation of glycolytic process(GO:0006110)
0.6 5.9 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.6 1.2 GO:0031627 telomeric loop formation(GO:0031627)
0.6 11.7 GO:2000674 type B pancreatic cell apoptotic process(GO:0097050) regulation of type B pancreatic cell apoptotic process(GO:2000674)
0.6 2.3 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.6 5.2 GO:0002934 desmosome organization(GO:0002934)
0.6 1.1 GO:0015747 urate transport(GO:0015747)
0.6 10.7 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.6 2.8 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.6 1.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.6 6.8 GO:0035878 nail development(GO:0035878)
0.6 25.6 GO:0014003 oligodendrocyte development(GO:0014003)
0.6 15.0 GO:0030539 male genitalia development(GO:0030539)
0.6 12.8 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.6 2.2 GO:0034201 response to oleic acid(GO:0034201)
0.5 4.4 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.5 1.6 GO:0044854 plasma membrane raft assembly(GO:0044854) plasma membrane raft organization(GO:0044857)
0.5 5.4 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.5 0.5 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.5 2.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.5 8.9 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.5 1.6 GO:0034135 regulation of toll-like receptor 2 signaling pathway(GO:0034135) positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
0.5 2.1 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.5 3.6 GO:0009249 protein lipoylation(GO:0009249)
0.5 3.6 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.5 5.7 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.5 27.6 GO:1990090 cellular response to nerve growth factor stimulus(GO:1990090)
0.5 1.0 GO:0061643 chemorepulsion of dopaminergic neuron axon(GO:0036518) chemorepulsion of axon(GO:0061643)
0.5 13.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.5 0.5 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.5 20.5 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.5 13.5 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.5 3.4 GO:1902855 nonmotile primary cilium assembly(GO:0035058) regulation of nonmotile primary cilium assembly(GO:1902855) positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.5 4.8 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.5 4.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.5 2.3 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.5 2.8 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.5 5.5 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.4 1.3 GO:1903677 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.4 12.9 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.4 18.6 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977) signal transduction involved in cell cycle checkpoint(GO:0072395) signal transduction involved in DNA integrity checkpoint(GO:0072401) signal transduction involved in DNA damage checkpoint(GO:0072422)
0.4 6.6 GO:0061162 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.4 2.2 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.4 1.3 GO:0061101 neuroendocrine cell differentiation(GO:0061101)
0.4 6.0 GO:0036158 outer dynein arm assembly(GO:0036158)
0.4 3.0 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.4 6.4 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.4 1.7 GO:1990502 dense core granule maturation(GO:1990502)
0.4 2.9 GO:0000076 DNA replication checkpoint(GO:0000076)
0.4 1.2 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.4 5.3 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.4 4.1 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.4 9.0 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.4 2.4 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.4 10.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.4 7.7 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.4 3.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.4 3.6 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.4 6.0 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.4 10.7 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA transport(GO:0051031) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.4 4.4 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742) positive regulation of skeletal muscle fiber development(GO:0048743)
0.4 3.9 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.4 2.0 GO:0090037 response to cobalamin(GO:0033590) positive regulation of protein kinase C signaling(GO:0090037)
0.4 1.9 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.4 5.0 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.4 0.4 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.4 0.4 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.4 1.5 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.4 0.8 GO:0085020 protein K6-linked ubiquitination(GO:0085020)
0.4 4.8 GO:0031114 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.4 1.5 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.4 1.5 GO:0034444 regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.4 5.8 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.4 4.6 GO:0009452 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.4 2.8 GO:0006572 tyrosine catabolic process(GO:0006572)
0.3 2.4 GO:0006450 regulation of translational fidelity(GO:0006450)
0.3 2.8 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.3 2.4 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.3 4.8 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.3 31.4 GO:0000209 protein polyubiquitination(GO:0000209)
0.3 2.7 GO:0061709 reticulophagy(GO:0061709)
0.3 59.9 GO:0006457 protein folding(GO:0006457)
0.3 1.0 GO:0010815 bradykinin catabolic process(GO:0010815)
0.3 1.3 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.3 3.0 GO:0031033 myosin filament organization(GO:0031033)
0.3 2.9 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.3 1.9 GO:0061743 motor learning(GO:0061743)
0.3 6.6 GO:0051865 protein autoubiquitination(GO:0051865)
0.3 1.6 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.3 1.9 GO:0006102 isocitrate metabolic process(GO:0006102)
0.3 1.5 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.3 35.9 GO:0030282 bone mineralization(GO:0030282)
0.3 2.8 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.3 3.3 GO:2000795 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.3 3.0 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.3 5.3 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.3 7.7 GO:0097484 dendrite extension(GO:0097484)
0.3 18.9 GO:0055007 cardiac muscle cell differentiation(GO:0055007)
0.3 0.3 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.3 1.8 GO:0060370 susceptibility to T cell mediated cytotoxicity(GO:0060370)
0.3 6.8 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.3 98.1 GO:0043687 post-translational protein modification(GO:0043687)
0.3 9.0 GO:0042733 embryonic digit morphogenesis(GO:0042733)
0.3 9.6 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.3 12.1 GO:0018196 peptidyl-asparagine modification(GO:0018196)
0.3 2.3 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.3 1.7 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.3 1.4 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.3 7.7 GO:0009060 aerobic respiration(GO:0009060)
0.3 7.6 GO:0060976 coronary vasculature development(GO:0060976)
0.3 7.3 GO:0035066 positive regulation of histone acetylation(GO:0035066) positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.3 3.3 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.3 1.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.3 1.4 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.3 25.3 GO:0046546 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.3 3.8 GO:0071539 protein localization to centrosome(GO:0071539)
0.3 1.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.3 0.8 GO:0042946 glucoside transport(GO:0042946)
0.3 4.1 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.3 0.5 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.3 0.5 GO:0036119 response to platelet-derived growth factor(GO:0036119)
0.3 3.6 GO:0044819 mitotic G1 DNA damage checkpoint(GO:0031571) mitotic G1/S transition checkpoint(GO:0044819)
0.3 1.8 GO:0046618 drug export(GO:0046618)
0.3 2.5 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.2 5.0 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.2 7.1 GO:0031398 positive regulation of protein ubiquitination(GO:0031398)
0.2 0.7 GO:0019046 release from viral latency(GO:0019046)
0.2 1.4 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.2 5.2 GO:0032008 positive regulation of TOR signaling(GO:0032008)
0.2 1.2 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.2 1.9 GO:0035897 proteolysis in other organism(GO:0035897)
0.2 33.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 0.7 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.2 1.4 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.2 2.6 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.2 1.8 GO:0090168 Golgi reassembly(GO:0090168)
0.2 1.1 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.2 5.0 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.2 1.9 GO:0090042 tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.2 2.1 GO:0006657 CDP-choline pathway(GO:0006657)
0.2 1.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.2 6.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.2 1.3 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2 1.1 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.2 2.4 GO:0006379 mRNA cleavage(GO:0006379)
0.2 1.0 GO:1904304 long-chain fatty acid import(GO:0044539) regulation of gastro-intestinal system smooth muscle contraction(GO:1904304) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.2 1.2 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.2 7.0 GO:0006693 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.2 1.7 GO:0033623 regulation of integrin activation(GO:0033623)
0.2 5.4 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.2 30.6 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.2 0.8 GO:0009305 protein biotinylation(GO:0009305) histone biotinylation(GO:0071110)
0.2 11.2 GO:0007338 single fertilization(GO:0007338)
0.2 0.5 GO:0032510 endosome to lysosome transport via multivesicular body sorting pathway(GO:0032510)
0.2 4.7 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.2 0.5 GO:1904814 regulation of protein localization to chromosome, telomeric region(GO:1904814) positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.2 2.4 GO:0045161 neuronal ion channel clustering(GO:0045161)
0.2 0.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.2 1.7 GO:0033363 secretory granule organization(GO:0033363)
0.2 3.3 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.2 1.5 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 3.2 GO:0042572 retinol metabolic process(GO:0042572)
0.2 1.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 5.7 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.2 0.9 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.2 0.3 GO:0042710 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.1 1.0 GO:0007288 sperm axoneme assembly(GO:0007288)
0.1 0.7 GO:0070091 glucagon secretion(GO:0070091) regulation of glucagon secretion(GO:0070092)
0.1 0.1 GO:0072513 regulation of secondary heart field cardioblast proliferation(GO:0003266) positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 5.7 GO:0016266 O-glycan processing(GO:0016266)
0.1 1.1 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.1 4.3 GO:0000726 non-recombinational repair(GO:0000726)
0.1 0.3 GO:1904031 positive regulation of cyclin-dependent protein kinase activity(GO:1904031)
0.1 7.0 GO:0030516 regulation of axon extension(GO:0030516)
0.1 9.0 GO:0007286 spermatid development(GO:0007286)
0.1 0.1 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.1 0.4 GO:1900363 regulation of mRNA polyadenylation(GO:1900363)
0.1 0.8 GO:0019732 antifungal humoral response(GO:0019732)
0.1 0.9 GO:0070307 lens fiber cell development(GO:0070307)
0.1 1.0 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219) retina vasculature development in camera-type eye(GO:0061298)
0.1 0.9 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 1.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 0.7 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1 1.3 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.1 0.6 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.6 GO:0098840 intraciliary transport(GO:0042073) protein transport along microtubule(GO:0098840)
0.1 6.0 GO:0015701 bicarbonate transport(GO:0015701)
0.1 0.7 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 1.6 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 0.7 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.1 0.4 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.9 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1 2.9 GO:0007040 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.1 0.2 GO:0021764 amygdala development(GO:0021764)
0.1 0.6 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.3 GO:0042320 vestibulocochlear nerve development(GO:0021562) positive regulation of dopamine secretion(GO:0033603) regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747)
0.1 0.7 GO:0051310 metaphase plate congression(GO:0051310)
0.1 2.4 GO:0019731 antibacterial humoral response(GO:0019731)
0.1 0.7 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 1.3 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.1 5.5 GO:0006333 chromatin assembly or disassembly(GO:0006333)
0.1 4.0 GO:0002209 behavioral fear response(GO:0001662) behavioral defense response(GO:0002209)
0.1 1.7 GO:0045332 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
0.1 2.3 GO:0042438 melanin metabolic process(GO:0006582) melanin biosynthetic process(GO:0042438)
0.1 0.2 GO:0045213 neurotransmitter receptor metabolic process(GO:0045213)
0.1 1.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.8 GO:1900037 regulation of cellular response to hypoxia(GO:1900037)
0.1 2.7 GO:0008542 visual learning(GO:0008542)
0.1 2.0 GO:0033344 cholesterol efflux(GO:0033344)
0.1 0.7 GO:0001541 ovarian follicle development(GO:0001541)
0.1 1.7 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.1 0.3 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.4 GO:0016246 RNA interference(GO:0016246)
0.1 0.7 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.1 1.1 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 11.0 GO:0007283 spermatogenesis(GO:0007283) male gamete generation(GO:0048232)
0.1 0.4 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.1 0.1 GO:0051280 negative regulation of release of sequestered calcium ion into cytosol(GO:0051280) positive regulation of sequestering of calcium ion(GO:0051284)
0.1 0.3 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.1 0.5 GO:0045333 cellular respiration(GO:0045333)
0.1 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.5 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.1 0.4 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 1.9 GO:0051932 synaptic transmission, GABAergic(GO:0051932)
0.1 1.3 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.1 2.1 GO:0001938 positive regulation of endothelial cell proliferation(GO:0001938)
0.1 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 1.8 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 0.3 GO:1904259 positive regulation of extracellular matrix assembly(GO:1901203) regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0 0.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 1.5 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.3 GO:0042426 choline catabolic process(GO:0042426)
0.0 1.0 GO:0015800 acidic amino acid transport(GO:0015800) L-glutamate transport(GO:0015813)
0.0 0.2 GO:0009070 serine family amino acid biosynthetic process(GO:0009070)
0.0 1.4 GO:0008344 adult locomotory behavior(GO:0008344)
0.0 0.1 GO:0090285 regulation of protein glycosylation in Golgi(GO:0090283) negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 4.5 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.0 1.0 GO:0006783 heme biosynthetic process(GO:0006783)
0.0 0.5 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.6 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.7 GO:0006826 iron ion transport(GO:0006826)
0.0 0.2 GO:0051934 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0 0.8 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.4 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.0 0.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.3 GO:0051004 regulation of lipoprotein lipase activity(GO:0051004)
0.0 1.5 GO:0016925 protein sumoylation(GO:0016925)
0.0 3.8 GO:0032446 protein modification by small protein conjugation(GO:0032446)
0.0 0.0 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.4 GO:0001935 endothelial cell proliferation(GO:0001935)
0.0 0.2 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0060426 lung vasculature development(GO:0060426) lung saccule development(GO:0060430) eyelid development in camera-type eye(GO:0061029) alveolar primary septum development(GO:0061143) paramesonephric duct development(GO:0061205)
0.0 0.4 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
13.6 68.0 GO:0000408 EKC/KEOPS complex(GO:0000408)
11.1 33.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
11.1 110.5 GO:0031595 nuclear proteasome complex(GO:0031595)
10.0 30.1 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
8.8 61.7 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
8.7 61.0 GO:0016272 prefoldin complex(GO:0016272)
8.0 24.1 GO:0097441 basilar dendrite(GO:0097441)
7.9 39.4 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
7.7 23.2 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
7.3 51.1 GO:0032021 NELF complex(GO:0032021)
7.3 79.9 GO:0070449 elongin complex(GO:0070449)
7.2 21.5 GO:0030689 Noc complex(GO:0030689)
6.9 61.9 GO:0032133 chromosome passenger complex(GO:0032133)
6.8 20.3 GO:1902737 dendritic filopodium(GO:1902737)
6.6 85.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
6.5 26.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
6.4 70.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
6.4 57.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
6.3 63.4 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
6.2 86.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
6.1 24.5 GO:0008537 proteasome activator complex(GO:0008537)
6.0 18.0 GO:0018444 translation release factor complex(GO:0018444)
5.7 28.6 GO:0070847 core mediator complex(GO:0070847)
5.6 28.1 GO:0032044 DSIF complex(GO:0032044)
5.6 56.0 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
5.5 21.9 GO:0005846 nuclear cap binding complex(GO:0005846)
5.3 95.0 GO:0030127 COPII vesicle coat(GO:0030127)
5.1 30.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
4.9 54.4 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
4.9 24.3 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
4.8 76.6 GO:0034709 methylosome(GO:0034709)
4.8 23.9 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
4.8 23.8 GO:0032449 CBM complex(GO:0032449)
4.8 19.0 GO:0071920 cleavage body(GO:0071920)
4.6 13.7 GO:0071817 MMXD complex(GO:0071817)
4.5 22.7 GO:0097149 centralspindlin complex(GO:0097149)
4.5 40.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
4.4 21.8 GO:0014802 terminal cisterna(GO:0014802)
4.3 171.9 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
4.2 58.7 GO:0001673 male germ cell nucleus(GO:0001673)
4.1 12.4 GO:0035370 UBC13-UEV1A complex(GO:0035370)
4.1 32.9 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
4.1 36.8 GO:0032797 SMN complex(GO:0032797)
3.9 85.4 GO:0036020 endolysosome membrane(GO:0036020)
3.7 37.2 GO:0043203 axon hillock(GO:0043203)
3.7 33.4 GO:0070765 gamma-secretase complex(GO:0070765)
3.7 29.4 GO:0097443 sorting endosome(GO:0097443)
3.6 67.9 GO:0016461 unconventional myosin complex(GO:0016461)
3.6 39.2 GO:0022624 proteasome accessory complex(GO:0022624)
3.6 10.7 GO:0032419 extrinsic component of lysosome membrane(GO:0032419)
3.5 67.3 GO:0005832 chaperonin-containing T-complex(GO:0005832)
3.5 7.1 GO:0000923 equatorial microtubule organizing center(GO:0000923)
3.5 28.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
3.5 31.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
3.4 20.4 GO:0000172 ribonuclease MRP complex(GO:0000172)
3.4 16.8 GO:1902560 GMP reductase complex(GO:1902560)
3.3 10.0 GO:0044611 nuclear pore inner ring(GO:0044611)
3.3 60.0 GO:0005685 U1 snRNP(GO:0005685)
3.3 10.0 GO:0070939 Dsl1p complex(GO:0070939)
3.3 29.8 GO:0005672 transcription factor TFIIA complex(GO:0005672)
3.3 29.7 GO:0072546 ER membrane protein complex(GO:0072546)
3.3 52.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
3.2 22.6 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
3.2 12.9 GO:0070876 SOSS complex(GO:0070876)
3.2 9.5 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
3.1 166.7 GO:0008180 COP9 signalosome(GO:0008180)
3.0 39.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
2.9 11.7 GO:0070435 Shc-EGFR complex(GO:0070435)
2.9 23.4 GO:0034464 BBSome(GO:0034464)
2.9 8.7 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
2.9 63.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
2.9 25.8 GO:0000813 ESCRT I complex(GO:0000813)
2.9 22.8 GO:0061689 tricellular tight junction(GO:0061689)
2.9 17.1 GO:0061617 MICOS complex(GO:0061617)
2.7 27.0 GO:0097255 R2TP complex(GO:0097255)
2.6 18.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
2.5 81.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
2.4 7.3 GO:0034455 t-UTP complex(GO:0034455)
2.3 18.5 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110) ERCC4-ERCC1 complex(GO:0070522)
2.3 25.2 GO:0030126 COPI vesicle coat(GO:0030126)
2.2 6.6 GO:0033565 ESCRT-0 complex(GO:0033565)
2.2 24.1 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
2.2 15.3 GO:0031298 replication fork protection complex(GO:0031298)
2.2 50.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
2.1 25.4 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
2.0 8.1 GO:0005721 pericentric heterochromatin(GO:0005721)
2.0 25.9 GO:1990023 mitotic spindle midzone(GO:1990023)
2.0 11.9 GO:0005945 6-phosphofructokinase complex(GO:0005945)
2.0 21.8 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
2.0 7.9 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
2.0 5.9 GO:0000243 commitment complex(GO:0000243)
2.0 43.0 GO:0030877 beta-catenin destruction complex(GO:0030877)
1.9 11.5 GO:0097451 glial limiting end-foot(GO:0097451)
1.9 22.8 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
1.9 5.6 GO:0016938 kinesin I complex(GO:0016938)
1.8 16.5 GO:0000439 core TFIIH complex(GO:0000439)
1.8 12.8 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
1.8 1.8 GO:1990111 spermatoproteasome complex(GO:1990111)
1.8 35.9 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
1.8 8.8 GO:0098837 postsynaptic recycling endosome(GO:0098837)
1.8 14.1 GO:0002080 acrosomal membrane(GO:0002080)
1.8 24.7 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
1.8 30.0 GO:0005839 proteasome core complex(GO:0005839)
1.8 7.0 GO:0005602 complement component C1 complex(GO:0005602)
1.7 8.7 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
1.7 5.1 GO:0071148 TEAD-1-YAP complex(GO:0071148)
1.6 6.5 GO:0030688 preribosome, small subunit precursor(GO:0030688)
1.6 40.0 GO:0044295 axonal growth cone(GO:0044295)
1.6 22.0 GO:0030914 STAGA complex(GO:0030914)
1.6 36.0 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
1.6 12.5 GO:0000796 condensin complex(GO:0000796)
1.6 43.5 GO:0032040 small-subunit processome(GO:0032040)
1.6 23.3 GO:0000812 Swr1 complex(GO:0000812)
1.5 13.8 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
1.5 4.5 GO:0043260 laminin-11 complex(GO:0043260)
1.5 8.9 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
1.5 7.4 GO:0005749 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
1.5 10.3 GO:1990745 EARP complex(GO:1990745)
1.4 28.3 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
1.4 12.7 GO:0033391 chromatoid body(GO:0033391)
1.4 2.8 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
1.4 14.0 GO:0043186 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
1.4 5.6 GO:0071986 Ragulator complex(GO:0071986)
1.4 8.4 GO:0071797 LUBAC complex(GO:0071797)
1.4 46.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
1.4 10.8 GO:0033276 transcription factor TFTC complex(GO:0033276)
1.3 10.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
1.3 7.9 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
1.3 6.6 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
1.3 65.0 GO:0005871 kinesin complex(GO:0005871)
1.3 20.5 GO:0031080 nuclear pore outer ring(GO:0031080)
1.3 3.8 GO:0071001 U4/U6 snRNP(GO:0071001)
1.3 7.6 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
1.3 64.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
1.2 3.7 GO:0005953 CAAX-protein geranylgeranyltransferase complex(GO:0005953)
1.2 7.4 GO:0070552 BRISC complex(GO:0070552)
1.2 6.1 GO:0042587 glycogen granule(GO:0042587)
1.2 59.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
1.2 4.6 GO:0005899 insulin receptor complex(GO:0005899)
1.2 5.8 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
1.1 29.6 GO:0031231 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
1.1 15.0 GO:0036452 ESCRT complex(GO:0036452)
1.1 28.8 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
1.0 17.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
1.0 3.1 GO:1902636 kinociliary basal body(GO:1902636)
1.0 9.1 GO:0042382 paraspeckles(GO:0042382)
1.0 58.3 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
1.0 11.6 GO:0005869 dynactin complex(GO:0005869)
0.9 3.8 GO:0017119 Golgi transport complex(GO:0017119)
0.9 8.5 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.9 9.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.9 49.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.9 41.7 GO:0005876 spindle microtubule(GO:0005876)
0.9 3.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.9 1.7 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.8 26.1 GO:0000421 autophagosome membrane(GO:0000421)
0.8 3.3 GO:0070695 FHF complex(GO:0070695)
0.8 2.5 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.8 8.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.8 12.7 GO:0005662 DNA replication factor A complex(GO:0005662)
0.8 25.0 GO:0031941 filamentous actin(GO:0031941)
0.8 3.9 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.8 36.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.8 3.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.7 3.7 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.7 2.2 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.7 8.0 GO:0042555 MCM complex(GO:0042555)
0.7 9.3 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.7 14.7 GO:0000502 proteasome complex(GO:0000502)
0.7 50.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.7 24.9 GO:0016592 mediator complex(GO:0016592)
0.7 11.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.7 201.0 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.7 13.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.7 31.3 GO:0005844 polysome(GO:0005844)
0.7 5.9 GO:0032009 early phagosome(GO:0032009)
0.7 23.0 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.6 3.9 GO:0031931 TORC1 complex(GO:0031931)
0.6 1.9 GO:0000805 X chromosome(GO:0000805) cyclin E2-CDK2 complex(GO:0097135)
0.6 8.8 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.6 97.8 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.6 6.8 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.6 1.8 GO:0000801 central element(GO:0000801)
0.6 9.8 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.6 18.8 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.6 3.6 GO:0030137 COPI-coated vesicle(GO:0030137)
0.6 5.3 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.6 5.8 GO:0016580 Sin3 complex(GO:0016580)
0.6 5.7 GO:0061574 ASAP complex(GO:0061574)
0.6 1.7 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.6 12.3 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.6 18.4 GO:0042629 mast cell granule(GO:0042629)
0.6 9.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.6 4.4 GO:0097470 ribbon synapse(GO:0097470)
0.6 6.6 GO:0090543 Flemming body(GO:0090543)
0.5 4.9 GO:0051233 spindle midzone(GO:0051233)
0.5 5.5 GO:0005686 U2 snRNP(GO:0005686)
0.5 13.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.5 15.9 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.5 14.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.5 12.3 GO:0099738 cell cortex region(GO:0099738)
0.5 7.1 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.5 1.9 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.5 8.0 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.5 6.1 GO:0042588 zymogen granule(GO:0042588)
0.5 2.8 GO:0033063 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.5 13.0 GO:0005640 nuclear outer membrane(GO:0005640)
0.5 3.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.5 2.3 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.4 4.0 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.4 5.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.4 1.7 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.4 3.9 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.4 13.4 GO:0032420 stereocilium(GO:0032420)
0.4 5.1 GO:0030008 TRAPP complex(GO:0030008)
0.4 18.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.4 7.7 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.4 5.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.4 1.6 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.4 6.7 GO:0033270 paranode region of axon(GO:0033270)
0.4 24.2 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.4 41.3 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.4 6.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.4 1.1 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.4 2.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.4 4.7 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.4 1.5 GO:0060091 kinocilium(GO:0060091)
0.4 17.5 GO:0043198 dendritic shaft(GO:0043198)
0.4 1.5 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.4 204.5 GO:0044429 mitochondrial part(GO:0044429)
0.4 42.7 GO:0005796 Golgi lumen(GO:0005796)
0.4 1.8 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.3 2.1 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.3 5.5 GO:0035102 PRC1 complex(GO:0035102)
0.3 6.5 GO:0036038 MKS complex(GO:0036038)
0.3 4.7 GO:0097225 sperm midpiece(GO:0097225)
0.3 13.1 GO:0016235 aggresome(GO:0016235)
0.3 4.0 GO:0097431 mitotic spindle pole(GO:0097431)
0.3 5.3 GO:0005922 connexon complex(GO:0005922)
0.3 88.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.3 5.2 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.3 3.8 GO:0005883 neurofilament(GO:0005883)
0.3 2.8 GO:0031312 extrinsic component of organelle membrane(GO:0031312)
0.3 5.3 GO:0000145 exocyst(GO:0000145)
0.3 13.1 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.3 3.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.3 1.8 GO:0005915 zonula adherens(GO:0005915)
0.3 11.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 21.2 GO:0005643 nuclear pore(GO:0005643)
0.3 11.4 GO:0090544 BAF-type complex(GO:0090544)
0.2 1.5 GO:0030905 retromer, tubulation complex(GO:0030905)
0.2 5.1 GO:0005861 troponin complex(GO:0005861)
0.2 4.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.2 11.5 GO:0036126 sperm flagellum(GO:0036126)
0.2 29.6 GO:0005802 trans-Golgi network(GO:0005802)
0.2 6.0 GO:0009898 cytoplasmic side of plasma membrane(GO:0009898)
0.2 0.9 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.2 31.1 GO:0043209 myelin sheath(GO:0043209)
0.2 30.4 GO:0043197 dendritic spine(GO:0043197)
0.2 20.5 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.2 0.6 GO:0098536 deuterosome(GO:0098536)
0.2 3.3 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 1.2 GO:0030684 preribosome(GO:0030684)
0.2 18.5 GO:0043202 lysosomal lumen(GO:0043202)
0.2 2.6 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.2 52.3 GO:0000790 nuclear chromatin(GO:0000790)
0.2 8.1 GO:0005901 caveola(GO:0005901)
0.2 16.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 9.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 2.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.2 2.5 GO:0005849 mRNA cleavage factor complex(GO:0005849)
0.2 24.1 GO:0030018 Z disc(GO:0030018)
0.2 34.6 GO:0005874 microtubule(GO:0005874)
0.2 1.8 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 15.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.2 96.8 GO:0005739 mitochondrion(GO:0005739)
0.1 1.0 GO:0032059 bleb(GO:0032059)
0.1 0.6 GO:0044447 axoneme part(GO:0044447)
0.1 4.5 GO:0031514 motile cilium(GO:0031514)
0.1 32.1 GO:0031965 nuclear membrane(GO:0031965)
0.1 1.0 GO:0031045 dense core granule(GO:0031045)
0.1 64.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 2.4 GO:0005801 cis-Golgi network(GO:0005801)
0.1 0.5 GO:1990879 CST complex(GO:1990879)
0.1 6.3 GO:0005635 nuclear envelope(GO:0005635)
0.1 3.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 0.7 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 5.9 GO:0031901 early endosome membrane(GO:0031901)
0.1 4.5 GO:0005604 basement membrane(GO:0005604)
0.1 0.6 GO:0033268 node of Ranvier(GO:0033268)
0.1 0.3 GO:0032302 MutSbeta complex(GO:0032302)
0.1 0.6 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 2.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 1.1 GO:0005581 collagen trimer(GO:0005581)
0.1 0.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 9.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 0.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.6 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.5 GO:0005875 microtubule associated complex(GO:0005875)
0.0 1.4 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.9 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.9 GO:0005811 lipid particle(GO:0005811)
0.0 10.6 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.0 0.5 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.4 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 3.8 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
21.5 64.5 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
14.3 43.0 GO:0044714 GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693)
11.9 35.7 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
11.8 59.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
11.7 58.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
11.1 33.2 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
10.0 30.1 GO:0031753 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
9.9 49.3 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
9.4 84.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
8.4 8.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
7.5 22.6 GO:0015140 malate transmembrane transporter activity(GO:0015140)
7.4 37.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
7.3 21.8 GO:0004750 ribulose-phosphate 3-epimerase activity(GO:0004750)
7.3 43.6 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
6.9 41.5 GO:0016807 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
6.7 60.7 GO:0035174 histone serine kinase activity(GO:0035174)
6.6 39.5 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
6.4 19.3 GO:0052815 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
5.6 44.9 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
5.4 37.8 GO:0032217 riboflavin transporter activity(GO:0032217)
5.4 21.6 GO:0004146 dihydrofolate reductase activity(GO:0004146)
5.2 31.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
5.1 40.9 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
5.1 35.6 GO:0061133 endopeptidase activator activity(GO:0061133)
4.9 14.8 GO:0030156 benzodiazepine receptor binding(GO:0030156)
4.6 27.8 GO:0043023 ribosomal large subunit binding(GO:0043023)
4.6 22.9 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
4.5 13.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
4.5 31.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
4.4 13.3 GO:0033699 DNA 5'-adenosine monophosphate hydrolase activity(GO:0033699)
4.1 24.5 GO:0034511 U3 snoRNA binding(GO:0034511)
4.0 11.9 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
3.9 23.4 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
3.9 11.6 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
3.9 19.3 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
3.8 30.6 GO:0071253 connexin binding(GO:0071253)
3.6 18.2 GO:0034046 poly(G) binding(GO:0034046)
3.5 14.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
3.5 119.6 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
3.5 10.5 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
3.5 7.0 GO:0001129 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
3.5 38.3 GO:1901612 cardiolipin binding(GO:1901612)
3.4 17.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
3.4 23.8 GO:0019788 NEDD8 transferase activity(GO:0019788)
3.4 16.9 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
3.4 16.8 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
3.4 10.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
3.3 23.3 GO:0050815 phosphoserine binding(GO:0050815)
3.3 16.7 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
3.3 52.3 GO:0001054 RNA polymerase I activity(GO:0001054)
3.2 16.2 GO:0001016 RNA polymerase III regulatory region DNA binding(GO:0001016)
3.2 22.6 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
3.2 91.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
3.0 9.0 GO:0055100 adiponectin binding(GO:0055100)
3.0 14.9 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
3.0 17.8 GO:0016531 copper chaperone activity(GO:0016531)
2.9 29.1 GO:0044388 small protein activating enzyme binding(GO:0044388)
2.9 8.7 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
2.9 60.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
2.8 102.1 GO:0001671 ATPase activator activity(GO:0001671)
2.8 16.8 GO:0048408 epidermal growth factor binding(GO:0048408)
2.8 13.9 GO:1990446 U1 snRNP binding(GO:1990446)
2.8 30.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
2.7 21.9 GO:0003993 acid phosphatase activity(GO:0003993)
2.7 27.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
2.7 75.7 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
2.6 59.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
2.6 20.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
2.5 30.4 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
2.5 25.3 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
2.5 72.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
2.5 60.0 GO:0000339 RNA cap binding(GO:0000339)
2.5 12.3 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113) peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
2.4 26.8 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
2.4 9.8 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
2.4 7.3 GO:0001849 complement component C1q binding(GO:0001849)
2.4 4.8 GO:0008384 IkappaB kinase activity(GO:0008384)
2.4 7.2 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
2.4 33.1 GO:0016783 sulfurtransferase activity(GO:0016783)
2.3 11.7 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
2.3 2.3 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
2.3 18.5 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
2.3 6.8 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
2.3 47.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
2.3 36.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
2.2 37.5 GO:0003688 DNA replication origin binding(GO:0003688)
2.2 8.7 GO:1990430 extracellular matrix protein binding(GO:1990430)
2.1 23.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
2.1 12.8 GO:0016748 succinyltransferase activity(GO:0016748)
2.1 4.2 GO:0097001 ceramide binding(GO:0097001)
2.1 8.3 GO:0030620 U2 snRNA binding(GO:0030620)
2.1 6.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
2.1 33.0 GO:0070513 death domain binding(GO:0070513)
2.1 6.2 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
2.0 7.9 GO:0035473 lipase binding(GO:0035473)
2.0 5.9 GO:0035375 zymogen binding(GO:0035375)
2.0 25.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
1.9 15.3 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
1.9 9.5 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
1.9 68.3 GO:0044183 protein binding involved in protein folding(GO:0044183)
1.8 7.4 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
1.8 37.6 GO:0008327 methyl-CpG binding(GO:0008327)
1.8 103.0 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
1.7 30.9 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
1.7 20.4 GO:0004526 ribonuclease P activity(GO:0004526)
1.7 13.5 GO:0008158 hedgehog receptor activity(GO:0008158)
1.7 16.6 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
1.6 29.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
1.6 9.8 GO:0003998 acylphosphatase activity(GO:0003998)
1.6 28.8 GO:0042809 vitamin D receptor binding(GO:0042809)
1.6 4.7 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
1.6 7.9 GO:0010340 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
1.6 6.3 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
1.6 20.3 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
1.6 7.8 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
1.6 4.7 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
1.5 6.2 GO:0004773 steryl-sulfatase activity(GO:0004773)
1.5 42.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
1.5 4.5 GO:0004157 dihydropyrimidinase activity(GO:0004157)
1.5 11.9 GO:0003872 6-phosphofructokinase activity(GO:0003872)
1.5 1.5 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
1.5 5.8 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
1.5 17.4 GO:0031386 protein tag(GO:0031386)
1.4 17.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
1.4 7.2 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
1.4 34.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
1.4 11.3 GO:0003696 satellite DNA binding(GO:0003696) centromeric DNA binding(GO:0019237)
1.4 84.5 GO:0004527 exonuclease activity(GO:0004527)
1.4 28.0 GO:0043495 protein anchor(GO:0043495)
1.4 143.9 GO:0008307 structural constituent of muscle(GO:0008307)
1.4 9.7 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
1.4 168.6 GO:0008565 protein transporter activity(GO:0008565)
1.4 8.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
1.3 10.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
1.3 12.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
1.3 18.7 GO:0046790 virion binding(GO:0046790)
1.3 17.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
1.3 68.4 GO:0003777 microtubule motor activity(GO:0003777)
1.3 6.6 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
1.3 1.3 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
1.3 37.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
1.3 18.0 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
1.3 9.0 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
1.3 52.5 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
1.3 5.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
1.2 3.7 GO:0004662 CAAX-protein geranylgeranyltransferase activity(GO:0004662)
1.2 3.7 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
1.2 6.1 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
1.2 16.8 GO:0030515 snoRNA binding(GO:0030515)
1.2 9.5 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
1.2 18.9 GO:0016018 cyclosporin A binding(GO:0016018)
1.2 3.5 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
1.2 4.7 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
1.2 11.7 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
1.2 55.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
1.1 4.6 GO:0032810 sterol response element binding(GO:0032810)
1.1 13.5 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
1.1 16.9 GO:0004985 opioid receptor activity(GO:0004985)
1.1 5.6 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
1.0 7.3 GO:0045505 dynein intermediate chain binding(GO:0045505)
1.0 61.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
1.0 6.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
1.0 3.0 GO:0002135 CTP binding(GO:0002135)
1.0 12.0 GO:0032036 myosin heavy chain binding(GO:0032036)
1.0 2.0 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
1.0 5.0 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
1.0 7.9 GO:0098821 BMP receptor activity(GO:0098821)
1.0 9.7 GO:0042731 PH domain binding(GO:0042731)
1.0 2.9 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.9 6.6 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.9 8.5 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.9 2.8 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.9 2.8 GO:0060001 minus-end directed microfilament motor activity(GO:0060001)
0.9 40.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.9 89.8 GO:0051082 unfolded protein binding(GO:0051082)
0.9 55.1 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.9 2.8 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.9 30.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.9 25.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.9 1.8 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.9 13.6 GO:0008517 folic acid transporter activity(GO:0008517)
0.9 5.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.9 6.3 GO:0051400 BH domain binding(GO:0051400)
0.9 36.9 GO:0043531 ADP binding(GO:0043531)
0.9 8.9 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.9 3.5 GO:1904288 BAT3 complex binding(GO:1904288)
0.9 48.5 GO:0031491 nucleosome binding(GO:0031491)
0.9 2.6 GO:0008424 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.9 3.4 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.9 8.6 GO:0004064 arylesterase activity(GO:0004064)
0.8 3.3 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.8 4.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.8 15.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.8 8.0 GO:0051879 Hsp90 protein binding(GO:0051879)
0.8 5.5 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.8 2.4 GO:0003896 DNA primase activity(GO:0003896)
0.8 18.8 GO:0017025 TBP-class protein binding(GO:0017025)
0.8 7.8 GO:0042288 MHC class I protein binding(GO:0042288)
0.8 17.8 GO:0070403 NAD+ binding(GO:0070403)
0.8 2.3 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.8 3.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.8 2.3 GO:0033981 D-dopachrome decarboxylase activity(GO:0033981)
0.8 6.8 GO:0001056 RNA polymerase III activity(GO:0001056)
0.8 3.8 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.8 15.8 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.7 5.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.7 18.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.7 26.2 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.7 31.9 GO:0031369 translation initiation factor binding(GO:0031369)
0.7 10.8 GO:0070628 proteasome binding(GO:0070628)
0.7 15.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.7 70.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.7 3.5 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.7 4.8 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.7 0.7 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.7 2.6 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.7 4.6 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.6 13.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.6 3.9 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.6 5.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.6 7.6 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.6 3.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.6 8.0 GO:0031489 myosin V binding(GO:0031489)
0.6 7.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.6 15.6 GO:0071617 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171) lysophospholipid acyltransferase activity(GO:0071617)
0.6 2.9 GO:0019776 Atg8 ligase activity(GO:0019776)
0.6 8.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.6 29.5 GO:0019894 kinesin binding(GO:0019894)
0.6 35.8 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.6 12.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.6 4.0 GO:0015288 porin activity(GO:0015288)
0.6 249.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.6 2.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.6 5.0 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.5 1.6 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.5 3.2 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.5 2.7 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.5 14.5 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.5 2.7 GO:0008494 translation activator activity(GO:0008494)
0.5 2.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823) procollagen galactosyltransferase activity(GO:0050211)
0.5 7.9 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.5 5.8 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.5 1.6 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.5 44.3 GO:0015405 primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405) ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.5 2.6 GO:0071532 ankyrin repeat binding(GO:0071532)
0.5 2.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.5 39.1 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.5 14.0 GO:0070064 proline-rich region binding(GO:0070064)
0.5 1.0 GO:0043515 kinetochore binding(GO:0043515)
0.5 7.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.5 5.3 GO:0005243 gap junction channel activity(GO:0005243)
0.5 1.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.5 6.1 GO:0000030 mannosyltransferase activity(GO:0000030)
0.5 3.8 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.5 1.9 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.5 8.8 GO:0005522 profilin binding(GO:0005522)
0.5 5.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.4 1.8 GO:0015307 drug:proton antiporter activity(GO:0015307)
0.4 3.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.4 2.2 GO:0016453 C-acetyltransferase activity(GO:0016453)
0.4 2.6 GO:0097322 7SK snRNA binding(GO:0097322)
0.4 5.5 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.4 3.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.4 1.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.4 28.0 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.4 7.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.4 7.2 GO:0019787 ubiquitin-like protein transferase activity(GO:0019787)
0.4 9.0 GO:0000049 tRNA binding(GO:0000049)
0.4 19.9 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.4 1.5 GO:0016524 latrotoxin receptor activity(GO:0016524)
0.4 1.5 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.4 5.9 GO:0070182 DNA polymerase binding(GO:0070182)
0.4 2.6 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.4 5.1 GO:0031014 troponin T binding(GO:0031014)
0.4 4.4 GO:0097602 cullin family protein binding(GO:0097602)
0.4 1.5 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.4 2.2 GO:0017091 AU-rich element binding(GO:0017091)
0.4 1.1 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.3 0.7 GO:0070568 guanylyltransferase activity(GO:0070568)
0.3 1.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.3 3.0 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.3 22.2 GO:0019003 GDP binding(GO:0019003)
0.3 5.6 GO:0070717 poly-purine tract binding(GO:0070717)
0.3 1.3 GO:0051373 FATZ binding(GO:0051373)
0.3 1.9 GO:0035173 histone kinase activity(GO:0035173)
0.3 3.5 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3 2.8 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.3 7.8 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.3 9.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.3 28.7 GO:0003697 single-stranded DNA binding(GO:0003697)
0.3 27.2 GO:0044389 ubiquitin-like protein ligase binding(GO:0044389)
0.3 1.4 GO:0030621 U4 snRNA binding(GO:0030621)
0.3 13.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.3 3.1 GO:0043022 ribosome binding(GO:0043022)
0.3 6.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.3 1.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.3 3.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.3 1.9 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.3 1.9 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.3 2.4 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.3 5.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.3 16.4 GO:0034212 peptide N-acetyltransferase activity(GO:0034212)
0.3 4.2 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.3 0.8 GO:0042947 glucoside transmembrane transporter activity(GO:0042947)
0.3 7.2 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.3 4.6 GO:0008242 omega peptidase activity(GO:0008242)
0.3 1.8 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.3 6.8 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.3 11.6 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.3 35.0 GO:0005262 calcium channel activity(GO:0005262)
0.3 44.3 GO:0004857 enzyme inhibitor activity(GO:0004857)
0.3 2.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.2 2.0 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.2 20.1 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 1.0 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.2 2.0 GO:0016015 morphogen activity(GO:0016015) BMP binding(GO:0036122)
0.2 5.5 GO:0033612 receptor serine/threonine kinase binding(GO:0033612)
0.2 12.0 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.2 3.2 GO:0019966 interleukin-1 binding(GO:0019966)
0.2 22.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 0.4 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.2 4.4 GO:0070888 E-box binding(GO:0070888)
0.2 0.7 GO:0004040 amidase activity(GO:0004040)
0.2 1.1 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.2 1.4 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.2 0.8 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.2 2.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.2 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 0.8 GO:0004080 biotin-[acetyl-CoA-carboxylase] ligase activity(GO:0004077) biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity(GO:0004078) biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity(GO:0004079) biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity(GO:0004080) biotin-protein ligase activity(GO:0018271)
0.2 2.4 GO:0003680 AT DNA binding(GO:0003680)
0.2 2.4 GO:0030275 LRR domain binding(GO:0030275)
0.2 3.2 GO:0097016 L27 domain binding(GO:0097016)
0.2 6.2 GO:0033558 histone deacetylase activity(GO:0004407) protein deacetylase activity(GO:0033558)
0.2 1.0 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.2 1.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.2 0.7 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.2 1.9 GO:0017166 vinculin binding(GO:0017166)
0.2 1.8 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.2 3.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 5.6 GO:0048487 beta-tubulin binding(GO:0048487)
0.2 12.1 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.2 8.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.2 0.5 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 1.6 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 0.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.1 1.0 GO:0005521 lamin binding(GO:0005521)
0.1 1.0 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.1 2.8 GO:0046875 ephrin receptor binding(GO:0046875)
0.1 0.3 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 18.3 GO:0005179 hormone activity(GO:0005179)
0.1 0.9 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 1.6 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 1.7 GO:0031005 filamin binding(GO:0031005)
0.1 2.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 0.6 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.1 2.6 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 3.3 GO:0005109 frizzled binding(GO:0005109)
0.1 0.4 GO:0002046 opsin binding(GO:0002046)
0.1 0.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 5.7 GO:0005507 copper ion binding(GO:0005507)
0.1 29.0 GO:0003924 GTPase activity(GO:0003924)
0.1 9.8 GO:0030165 PDZ domain binding(GO:0030165)
0.1 23.0 GO:0045296 cadherin binding(GO:0045296)
0.1 0.7 GO:0004331 fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) phosphofructokinase activity(GO:0008443)
0.1 2.6 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 2.0 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1 3.0 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.7 GO:0039706 co-receptor binding(GO:0039706)
0.1 3.3 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.7 GO:0019841 retinol binding(GO:0019841)
0.1 1.7 GO:0043492 ATPase activity, coupled to movement of substances(GO:0043492)
0.1 0.4 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 1.8 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 21.7 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 1.8 GO:0042805 actinin binding(GO:0042805)
0.1 7.2 GO:0000149 SNARE binding(GO:0000149)
0.1 12.9 GO:0016887 ATPase activity(GO:0016887)
0.1 37.6 GO:0008134 transcription factor binding(GO:0008134)
0.1 0.3 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 1.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 44.4 GO:0005509 calcium ion binding(GO:0005509)
0.1 3.6 GO:0019239 deaminase activity(GO:0019239)
0.1 25.0 GO:0046873 metal ion transmembrane transporter activity(GO:0046873)
0.1 0.7 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 1.1 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 11.3 GO:0015631 tubulin binding(GO:0015631)
0.1 0.6 GO:0051184 cofactor transporter activity(GO:0051184)
0.1 0.3 GO:0003796 lysozyme activity(GO:0003796)
0.1 1.1 GO:0005537 mannose binding(GO:0005537)
0.1 76.3 GO:0003723 RNA binding(GO:0003723)
0.1 0.7 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.1 67.3 GO:0042802 identical protein binding(GO:0042802)
0.1 4.5 GO:0032947 protein complex scaffold(GO:0032947)
0.1 2.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.6 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.7 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.1 GO:0032090 Pyrin domain binding(GO:0032090)
0.1 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 1.4 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.5 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.7 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 1.5 GO:0005319 lipid transporter activity(GO:0005319)
0.0 0.2 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.7 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.1 GO:0009374 biotin binding(GO:0009374)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
3.9 104.8 PID ARF 3PATHWAY Arf1 pathway
3.6 42.9 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
3.1 174.1 PID AURORA A PATHWAY Aurora A signaling
2.4 72.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
2.3 66.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
1.4 39.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
1.4 30.7 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
1.3 75.3 PID ATR PATHWAY ATR signaling pathway
1.2 65.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
1.1 47.4 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
1.1 21.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
1.0 35.8 PID MYC PATHWAY C-MYC pathway
1.0 20.1 PID ALK2 PATHWAY ALK2 signaling events
0.9 18.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.9 53.5 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.9 37.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.9 23.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.9 24.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.8 30.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.7 7.9 PID ALK1 PATHWAY ALK1 signaling events
0.6 57.9 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.6 28.3 PID AURORA B PATHWAY Aurora B signaling
0.6 15.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.6 48.3 PID TGFBR PATHWAY TGF-beta receptor signaling
0.6 12.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.6 5.9 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.6 25.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.6 10.5 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.5 13.1 PID S1P S1P1 PATHWAY S1P1 pathway
0.5 17.5 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.5 4.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.5 9.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.5 8.0 PID BARD1 PATHWAY BARD1 signaling events
0.5 10.8 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.4 18.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.4 9.0 ST GA12 PATHWAY G alpha 12 Pathway
0.4 21.7 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.4 14.4 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.4 4.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.4 1.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.4 29.3 PID AP1 PATHWAY AP-1 transcription factor network
0.3 18.3 PID ILK PATHWAY Integrin-linked kinase signaling
0.3 0.7 PID TRAIL PATHWAY TRAIL signaling pathway
0.3 24.3 PID CDC42 PATHWAY CDC42 signaling events
0.3 20.6 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.3 4.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.3 4.4 PID ATM PATHWAY ATM pathway
0.3 2.8 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.3 2.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.3 11.4 PID ERBB4 PATHWAY ErbB4 signaling events
0.3 3.1 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.3 14.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 3.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.2 10.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.2 8.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.2 2.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.2 1.0 PID IFNG PATHWAY IFN-gamma pathway
0.2 3.2 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.2 8.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.2 3.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.2 5.0 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.5 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.1 0.8 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 5.8 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 3.7 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 25.9 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 3.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 9.8 PID CMYB PATHWAY C-MYB transcription factor network
0.1 1.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 2.1 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.1 1.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 0.9 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 0.8 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.1 14.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.7 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 7.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.9 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.9 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 ST FAS SIGNALING PATHWAY Fas Signaling Pathway
0.0 0.2 PID IGF1 PATHWAY IGF1 pathway
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 84.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
4.2 271.6 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
3.9 96.8 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
3.4 89.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
3.4 151.2 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
3.2 174.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
2.9 52.9 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
2.9 81.3 REACTOME KINESINS Genes involved in Kinesins
2.9 42.9 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
2.9 54.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
2.7 159.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
2.6 80.5 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
2.5 27.7 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
2.5 39.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
2.4 100.4 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
2.4 26.9 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
2.4 39.1 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
2.4 43.6 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
2.3 44.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
2.2 32.5 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
2.1 22.9 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
2.0 164.3 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
1.9 9.4 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
1.8 30.9 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
1.8 54.2 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
1.8 30.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
1.7 93.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
1.7 8.5 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
1.7 35.3 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
1.6 28.4 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
1.5 24.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
1.5 34.7 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
1.4 12.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
1.3 30.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
1.3 15.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
1.3 45.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
1.2 25.7 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
1.1 16.0 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
1.1 25.8 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
1.1 16.0 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
1.0 18.9 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
1.0 27.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
1.0 178.1 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
1.0 2.0 REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
1.0 24.2 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.9 22.3 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.9 19.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.9 16.4 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.8 13.4 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.8 18.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.8 39.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.8 19.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.8 16.0 REACTOME SIGNALING BY WNT Genes involved in Signaling by Wnt
0.7 6.0 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.7 16.0 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.7 6.4 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.7 16.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.7 41.6 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.7 22.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.7 12.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.7 14.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.6 7.0 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.6 15.7 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.6 4.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.5 8.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.5 22.8 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.5 1.1 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.5 1.5 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.5 5.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.5 5.6 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.5 14.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.5 9.8 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.4 16.5 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.4 26.2 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.4 18.4 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.4 4.9 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.4 13.0 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.4 31.1 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.4 7.4 REACTOME PROTEIN FOLDING Genes involved in Protein folding
0.4 3.1 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.4 1.5 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.3 2.2 REACTOME RNA POL II PRE TRANSCRIPTION EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.3 8.1 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.3 3.4 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.3 5.2 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.3 27.8 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.3 34.2 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.3 7.6 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.3 3.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.3 4.3 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.3 3.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 2.5 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.2 15.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.2 4.7 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.2 4.9 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.2 1.8 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.2 3.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 14.8 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis
0.2 3.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.2 5.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.2 4.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 7.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.2 6.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 4.5 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.2 2.6 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.2 3.0 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.2 3.1 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.2 4.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 2.0 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.2 3.6 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 1.8 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.6 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.1 4.7 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 1.6 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 1.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 5.1 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.1 1.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 1.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.1 3.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.6 REACTOME RNA POL III TRANSCRIPTION Genes involved in RNA Polymerase III Transcription
0.1 1.1 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.4 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 0.7 REACTOME PURINE METABOLISM Genes involved in Purine metabolism
0.1 1.4 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 1.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.9 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 1.9 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 2.1 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.9 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.1 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT