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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ETV2

Z-value: 1.16

Motif logo

Transcription factors associated with ETV2

Gene Symbol Gene ID Gene Info
ENSG00000105672.14 ETV2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ETV2hg38_v1_chr19_+_35641728_356417930.119.5e-02Click!

Activity profile of ETV2 motif

Sorted Z-values of ETV2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ETV2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_+_70398404 13.78 ENST00000346329.7
ENST00000301843.13
ENST00000376561.7
cortactin
chrX_+_47585212 13.43 ENST00000445623.1
TIMP metallopeptidase inhibitor 1
chr7_+_101127095 12.97 ENST00000223095.5
serpin family E member 1
chr4_-_57110373 12.84 ENST00000295666.6
ENST00000514062.2
insulin like growth factor binding protein 7
chr1_+_98661666 12.50 ENST00000529992.5
sorting nexin 7
chr1_+_98661709 12.25 ENST00000306121.8
sorting nexin 7
chr3_+_57556244 10.86 ENST00000311180.9
ENST00000487257.1
phosphodiesterase 12
chr1_-_9943314 10.81 ENST00000377223.6
ENST00000377213.1
leucine zipper and CTNNBIP1 domain containing
chr2_-_109614143 10.43 ENST00000356688.8
septin 10
chr11_+_72080313 10.43 ENST00000307198.11
ENST00000538413.6
ENST00000642648.1
ENST00000289488.7
leucine rich transmembrane and O-methyltransferase domain containing
leucine rich transmembrane and O-methyltransferase domain containing
chr7_-_50093204 10.30 ENST00000419417.5
ENST00000046087.7
zona pellucida binding protein
chr2_-_109613835 10.23 ENST00000415095.5
ENST00000437928.5
ENST00000493445.5
ENST00000397714.6
ENST00000461295.1
ENST00000397712.7
septin 10
chr8_+_144078661 10.04 ENST00000316052.6
exosome component 4
chr6_-_168075831 9.73 ENST00000440994.6
FERM domain containing 1
chr1_-_169367746 9.72 ENST00000367811.8
ENST00000472647.5
NME/NM23 family member 7
chr19_+_57584131 9.61 ENST00000536878.6
ENST00000597219.1
ENST00000598689.1
ENST00000597850.2
zinc finger protein interacting with K protein 1
chr2_-_237414127 9.53 ENST00000472056.5
collagen type VI alpha 3 chain
chrX_-_40735476 9.14 ENST00000324817.6
mediator complex subunit 14
chr2_-_237414157 9.08 ENST00000295550.9
ENST00000353578.9
ENST00000392004.7
ENST00000433762.1
ENST00000392003.6
collagen type VI alpha 3 chain
chr7_+_128739395 9.04 ENST00000479257.5
calumenin
chr19_-_8832286 9.00 ENST00000601372.6
zinc finger protein 558
chr7_+_128739292 8.79 ENST00000535011.6
ENST00000542996.6
ENST00000249364.9
ENST00000449187.6
calumenin
chrX_-_104156976 8.71 ENST00000594199.3
solute carrier family 25 member 53
chr4_+_75514455 8.64 ENST00000508105.5
ENST00000311638.7
ENST00000380837.7
ENST00000507556.5
ENST00000504190.5
ENST00000507885.5
ENST00000502620.1
ENST00000514480.1
THAP domain containing 6
chr11_+_72080803 8.61 ENST00000423494.6
ENST00000539587.6
ENST00000536917.2
ENST00000538478.5
ENST00000324866.11
ENST00000643715.1
ENST00000439209.5
leucine rich transmembrane and O-methyltransferase domain containing
leucine rich transmembrane and O-methyltransferase domain containing
chr1_-_153985366 8.53 ENST00000614713.4
RAB13, member RAS oncogene family
chrX_+_30215551 8.48 ENST00000378988.5
MAGE family member B2
chrX_-_100636799 8.36 ENST00000373020.9
tetraspanin 6
chr5_+_95731300 8.35 ENST00000379982.8
Rho related BTB domain containing 3
chr11_+_72080595 8.32 ENST00000647530.1
ENST00000539271.6
ENST00000642510.1
leucine rich transmembrane and O-methyltransferase domain containing
chr15_+_90265634 8.09 ENST00000379095.5
neugrin, neurite outgrowth associated
chr12_-_47079859 7.94 ENST00000266581.4
adhesion molecule with Ig like domain 2
chr8_-_120445092 7.81 ENST00000518918.1
mitochondrial ribosomal protein L13
chr7_+_44044663 7.78 ENST00000456905.5
ENST00000440166.5
ENST00000452943.5
ENST00000448521.6
ENST00000468694.5
ENST00000494774.5
drebrin like
chr9_+_36190908 7.72 ENST00000345519.10
ENST00000470744.5
ENST00000242285.10
ENST00000466396.5
ENST00000396603.6
clathrin light chain A
chr12_-_105236074 7.71 ENST00000551662.5
ENST00000553097.5
ENST00000258530.8
adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2
chr3_+_100709290 7.64 ENST00000675047.1
ENST00000490574.6
ENST00000675543.1
ENST00000676308.1
ENST00000675499.1
trafficking from ER to golgi regulator
chr1_-_1375490 7.60 ENST00000338338.9
aurora kinase A interacting protein 1
chr6_+_151239951 7.59 ENST00000402676.7
A-kinase anchoring protein 12
chr1_-_1375150 7.59 ENST00000338370.7
ENST00000321751.9
ENST00000378853.3
aurora kinase A interacting protein 1
chr5_+_126423176 7.55 ENST00000542322.5
ENST00000544396.5
GRAM domain containing 2B
chr8_-_120445140 7.39 ENST00000306185.8
mitochondrial ribosomal protein L13
chr8_+_144078590 7.37 ENST00000525936.1
exosome component 4
chrX_+_51803007 7.16 ENST00000375772.7
MAGE family member D1
chr5_+_892844 7.13 ENST00000166345.8
thyroid hormone receptor interactor 13
chr1_-_85276467 6.99 ENST00000648566.1
BCL10 immune signaling adaptor
chr20_-_56392131 6.96 ENST00000422322.5
ENST00000371356.6
ENST00000451915.1
ENST00000347343.6
ENST00000395911.5
ENST00000395915.8
ENST00000395907.5
ENST00000441357.5
ENST00000456249.5
ENST00000420474.5
ENST00000395914.5
ENST00000312783.10
ENST00000395913.7
aurora kinase A
chr5_+_126423363 6.90 ENST00000285689.8
GRAM domain containing 2B
chr3_-_94062906 6.85 ENST00000314636.3
ENST00000394221.3
dihydrofolate reductase 2
chr11_+_74171266 6.76 ENST00000328257.13
ENST00000398427.6
protein phosphatase methylesterase 1
chr5_+_126423122 6.73 ENST00000515200.5
GRAM domain containing 2B
chr16_-_11915991 6.72 ENST00000420576.6
G1 to S phase transition 1
chr1_+_169368175 6.69 ENST00000367808.8
ENST00000426663.1
basic leucine zipper nuclear factor 1
chr20_+_44475867 6.65 ENST00000262605.9
ENST00000372904.7
ENST00000372906.2
ENST00000456317.1
alpha tocopherol transfer protein like
chr1_-_43172504 6.59 ENST00000431635.6
EBNA1 binding protein 2
chr11_-_31804067 6.57 ENST00000639548.1
ENST00000640125.1
ENST00000481563.6
ENST00000639079.1
ENST00000638762.1
ENST00000638346.1
paired box 6
chr3_-_94062881 6.56 ENST00000619045.1
dihydrofolate reductase 2
chr3_+_100709344 6.55 ENST00000418917.7
ENST00000675553.1
trafficking from ER to golgi regulator
chr16_+_20806517 6.55 ENST00000348433.10
ENST00000568501.5
ENST00000261377.11
ENST00000566276.5
RNA exonuclease 5
chr3_-_28348805 6.53 ENST00000457172.5
ENST00000479665.6
5-azacytidine induced 2
chr7_-_108003122 6.52 ENST00000393559.2
ENST00000222399.11
ENST00000676777.1
ENST00000439976.6
ENST00000393560.5
ENST00000677793.1
ENST00000679244.1
laminin subunit beta 1
chr16_+_20806698 6.49 ENST00000564274.5
ENST00000563068.1
RNA exonuclease 5
chr17_-_34961400 6.46 ENST00000421975.7
chaperonin containing TCP1 subunit 6B
chr11_+_119018746 6.26 ENST00000528230.5
ENST00000525303.5
ENST00000434101.6
ENST00000359005.8
ENST00000533632.6
ENST00000533058.5
trafficking protein particle complex 4
chr1_+_38012706 6.21 ENST00000373014.5
UTP11 small subunit processome component
chr17_-_34961448 6.17 ENST00000436961.7
ENST00000314144.10
chaperonin containing TCP1 subunit 6B
chr3_+_100709382 6.16 ENST00000620299.5
trafficking from ER to golgi regulator
chr11_+_18322253 6.16 ENST00000453096.6
general transcription factor IIH subunit 1
chr9_+_36190856 6.15 ENST00000433436.6
ENST00000538225.5
ENST00000540080.5
clathrin light chain A
chr11_+_125903320 6.13 ENST00000525943.1
DEAD-box helicase 25
chr1_-_43389768 6.00 ENST00000372455.4
ENST00000372457.9
ENST00000290663.10
mediator complex subunit 8
chr12_+_53098846 5.96 ENST00000650247.1
ENST00000549628.1
insulin like growth factor binding protein 6
chr17_-_15684288 5.93 ENST00000416464.6
ENST00000578237.5
ENST00000581200.1
ENST00000649191.2
tripartite motif containing 16
chr3_+_100709424 5.85 ENST00000675246.1
ENST00000675692.1
ENST00000675890.1
ENST00000675586.1
ENST00000674645.1
ENST00000675958.1
ENST00000479672.6
ENST00000675420.1
ENST00000674615.1
ENST00000676431.1
ENST00000674758.1
trafficking from ER to golgi regulator
chr1_+_154974653 5.84 ENST00000368439.5
CDC28 protein kinase regulatory subunit 1B
chr17_+_7252237 5.75 ENST00000570500.5
elongator acetyltransferase complex subunit 5
chr1_-_43172244 5.69 ENST00000236051.3
EBNA1 binding protein 2
chr1_-_112704921 5.61 ENST00000414971.1
ENST00000534717.5
ras homolog family member C
chr17_+_1771688 5.57 ENST00000572048.1
ENST00000573763.1
serpin family F member 1
chr3_+_100709473 5.53 ENST00000240851.9
ENST00000675243.1
ENST00000676111.1
ENST00000476228.5
ENST00000463568.6
ENST00000676395.1
trafficking from ER to golgi regulator
chr17_+_35587478 5.49 ENST00000618940.4
adaptor related protein complex 2 subunit beta 1
chr6_+_111259474 5.46 ENST00000672554.1
ENST00000673024.1
major facilitator superfamily domain containing 4B
chr3_-_129161034 5.45 ENST00000418265.1
ENST00000393292.7
ENST00000273541.12
ENST00000393295.8
ISY1-RAB43 readthrough
ISY1 splicing factor homolog
chr7_-_99408548 5.38 ENST00000626285.1
ENST00000350498.8
PDGFA associated protein 1
chr7_-_19117625 5.29 ENST00000242261.6
twist family bHLH transcription factor 1
chr5_+_134905100 5.27 ENST00000512783.5
ENST00000254908.11
pterin-4 alpha-carbinolamine dehydratase 2
chr15_+_69414304 5.23 ENST00000352331.8
ENST00000679126.1
ENST00000647715.1
ENST00000559279.6
kinesin family member 23
chr10_-_15860450 5.19 ENST00000277632.8
MINDY lysine 48 deubiquitinase 3
chr7_-_150323489 5.09 ENST00000683684.1
ENST00000478393.5
actin related protein 3C
chr15_+_69414246 5.00 ENST00000260363.9
ENST00000395392.6
kinesin family member 23
chr6_-_109440504 4.98 ENST00000520723.5
ENST00000518648.1
ENST00000417394.6
ENST00000521072.7
peptidylprolyl isomerase like 6
chr17_+_7252024 4.92 ENST00000573513.5
ENST00000354429.6
ENST00000574255.5
ENST00000356683.6
ENST00000396627.6
elongator acetyltransferase complex subunit 5
chr15_-_70892412 4.91 ENST00000249861.9
THAP domain containing 10
chrX_+_7147819 4.91 ENST00000660000.2
steroid sulfatase
chr2_+_102104563 4.88 ENST00000409589.5
ENST00000409329.5
interleukin 1 receptor type 1
chr17_-_57850010 4.85 ENST00000313608.13
ENST00000578444.1
ENST00000579380.1
mitochondrial ribosomal protein S23
chr17_+_7252268 4.80 ENST00000396628.6
ENST00000574993.5
ENST00000573657.5
elongator acetyltransferase complex subunit 5
chr11_-_6481350 4.78 ENST00000423813.6
ENST00000614314.4
ADP ribosylation factor interacting protein 2
chr1_+_44746401 4.77 ENST00000372217.5
kinesin family member 2C
chr2_+_176269406 4.73 ENST00000249442.11
ENST00000443241.5
metaxin 2
chr7_+_12686849 4.62 ENST00000396662.5
ENST00000356797.7
ENST00000396664.2
ADP ribosylation factor like GTPase 4A
chr1_+_232950580 4.59 ENST00000366628.10
ENST00000366627.4
nucleoside-triphosphatase, cancer-related
chr19_+_47256518 4.56 ENST00000643617.1
ENST00000221922.11
coiled-coil domain containing 9
chr12_-_124917340 4.55 ENST00000542416.1
ubiquitin C
chr17_+_7252502 4.55 ENST00000570322.5
ENST00000576496.5
ENST00000574841.2
elongator acetyltransferase complex subunit 5
chr2_+_176269473 4.55 ENST00000452865.1
metaxin 2
chr22_-_37519349 4.52 ENST00000251973.10
caspase recruitment domain family member 10
chr6_+_49463360 4.52 ENST00000335783.4
centromere protein Q
chr7_+_90154442 4.49 ENST00000297205.7
STEAP family member 1
chr12_-_13095628 4.47 ENST00000457134.6
ENST00000537302.5
germ cell associated 1
chr3_-_16605416 4.47 ENST00000399444.7
deleted in azoospermia like
chr3_+_139343996 4.45 ENST00000680020.1
ENST00000310776.9
ENST00000465373.5
mitochondrial ribosomal protein S22
chr7_-_151877105 4.41 ENST00000287878.9
ENST00000652321.1
protein kinase AMP-activated non-catalytic subunit gamma 2
chr11_-_62709493 4.40 ENST00000405837.5
ENST00000531524.5
ENST00000524862.6
ENST00000679883.1
BSCL2 lipid droplet biogenesis associated, seipin
chr20_+_19886506 4.36 ENST00000648440.1
Ras and Rab interactor 2
chr16_-_3256587 4.32 ENST00000536379.5
ENST00000541159.5
ENST00000339854.8
ENST00000219596.6
MEFV innate immuity regulator, pyrin
chr6_-_56851888 4.32 ENST00000312431.10
ENST00000520645.5
dystonin
chr6_-_11382247 4.29 ENST00000397378.7
ENST00000513989.5
ENST00000508546.5
ENST00000504387.5
neural precursor cell expressed, developmentally down-regulated 9
chr5_+_96743536 4.27 ENST00000515663.5
calpastatin
chr11_+_2400488 4.22 ENST00000380996.9
ENST00000380992.5
ENST00000333256.11
ENST00000437110.5
ENST00000435795.5
tumor suppressing subtransferable candidate 4
chr2_+_109614328 4.21 ENST00000356454.5
sosondowah ankyrin repeat domain family member C
chr6_+_52420992 4.18 ENST00000636954.1
ENST00000636566.1
ENST00000638075.1
EF-hand domain containing 1
chr6_+_150683593 4.14 ENST00000644968.1
pleckstrin homology and RhoGEF domain containing G1
chr6_+_31666128 4.11 ENST00000375865.6
ENST00000375866.2
casein kinase 2 beta
chr12_-_6689244 4.10 ENST00000361959.7
ENST00000436774.6
ENST00000544482.1
zinc finger protein 384
chr22_-_37519528 4.08 ENST00000403299.5
caspase recruitment domain family member 10
chr2_-_99154910 4.07 ENST00000393483.8
testis specific 10
chr17_+_68512878 4.03 ENST00000585981.5
ENST00000589480.5
ENST00000585815.5
protein kinase cAMP-dependent type I regulatory subunit alpha
chr11_-_6481304 4.01 ENST00000254584.6
ENST00000525235.1
ENST00000396777.8
ENST00000445086.6
ADP ribosylation factor interacting protein 2
chr6_+_125919296 3.94 ENST00000444128.2
nuclear receptor coactivator 7
chr2_+_112584586 3.94 ENST00000409719.1
coiled-coil-helix-coiled-coil-helix domain containing 5
chr12_-_13095798 3.94 ENST00000396302.7
germ cell associated 1
chr14_-_24188787 3.93 ENST00000625289.1
ENST00000354464.11
importin 4
chr3_-_49018558 3.92 ENST00000441576.6
ENST00000420952.2
ENST00000341949.9
DALR anticodon binding domain containing 3
chr17_+_42833390 3.90 ENST00000590720.6
ENST00000586114.5
ENST00000585805.5
ENST00000441946.6
ENST00000591152.5
ENST00000589469.5
ENST00000293362.7
ENST00000592169.2
proteasome activator subunit 3
chr17_-_2336435 3.90 ENST00000301364.10
ENST00000576112.2
TSR1 ribosome maturation factor
chr19_+_48993525 3.89 ENST00000601968.5
ENST00000596837.5
RuvB like AAA ATPase 2
chr6_-_31958935 3.85 ENST00000441998.5
ENST00000444811.6
ENST00000375429.8
negative elongation factor complex member E
chrX_+_11111291 3.85 ENST00000321143.8
ENST00000380762.5
ENST00000380763.7
holocytochrome c synthase
chr2_-_55269038 3.84 ENST00000417363.5
ENST00000412530.1
ENST00000366137.6
ENST00000420637.5
mitochondrial translational initiation factor 2
chr11_+_6481473 3.83 ENST00000530751.1
ENST00000254616.11
translocase of inner mitochondrial membrane 10B
chr5_-_144170607 3.79 ENST00000448443.6
ENST00000513112.5
ENST00000519064.5
ENST00000274496.10
ENST00000522203.5
Yip1 domain family member 5
chr6_-_138107412 3.79 ENST00000421351.4
p53 apoptosis effector related to PMP22
chr16_+_69339758 3.76 ENST00000254940.10
ENST00000254941.6
nucleolar pre-rRNA processing protein NIP7
chr6_+_31652414 3.74 ENST00000375918.6
ENST00000375920.8
apolipoprotein M
chr10_-_78029487 3.73 ENST00000372371.8
RNA polymerase III subunit A
chr1_-_28643005 3.73 ENST00000263974.4
ENST00000373824.9
ENST00000495422.2
TATA-box binding protein associated factor 12
chr6_-_33271835 3.72 ENST00000482399.5
ENST00000445902.3
VPS52 subunit of GARP complex
chr1_+_169367934 3.72 ENST00000367807.7
ENST00000329281.6
ENST00000420531.1
basic leucine zipper nuclear factor 1
chr8_+_30744150 3.69 ENST00000265616.10
ENST00000341403.9
ENST00000615729.4
UBX domain protein 8
chr1_-_156741124 3.67 ENST00000368211.8
mitochondrial ribosomal protein L24
chr6_+_125919210 3.64 ENST00000438495.6
nuclear receptor coactivator 7
chr6_-_31652678 3.64 ENST00000437771.5
ENST00000362049.10
ENST00000439687.6
ENST00000211379.9
ENST00000375964.11
ENST00000676571.1
ENST00000676615.1
BAG cochaperone 6
chr11_+_18322541 3.63 ENST00000534641.5
ENST00000265963.9
ENST00000525831.5
general transcription factor IIH subunit 1
chr13_-_33185994 3.60 ENST00000255486.8
StAR related lipid transfer domain containing 13
chrX_+_54808334 3.60 ENST00000218439.8
MAGE family member D2
chr7_+_134843884 3.59 ENST00000445569.6
caldesmon 1
chr21_-_35049238 3.59 ENST00000416754.1
ENST00000437180.5
ENST00000455571.5
ENST00000675419.1
RUNX family transcription factor 1
chr12_+_50112167 3.55 ENST00000548468.2
ENST00000552815.1
ENST00000550654.1
ENST00000550487.6
ENST00000548985.1
novel transcript, antisense to CERS5
cytochrome c oxidase assembly factor COX14
chrX_+_54808359 3.54 ENST00000375058.5
ENST00000375060.5
MAGE family member D2
chr2_+_118088432 3.51 ENST00000245787.9
insulin induced gene 2
chr12_+_80716906 3.51 ENST00000228644.4
myogenic factor 5
chr9_-_33264559 3.49 ENST00000473781.1
ENST00000379704.7
ENST00000488499.1
BAG cochaperone 1
chr1_-_154974361 3.47 ENST00000368453.8
ENST00000368450.5
SHC adaptor protein 1
chr17_-_67366562 3.47 ENST00000356126.8
ENST00000357146.4
proteasome 26S subunit, non-ATPase 12
chr1_-_156741067 3.46 ENST00000361531.6
ENST00000412846.5
mitochondrial ribosomal protein L24
chr12_-_13095664 3.45 ENST00000337630.10
ENST00000545699.1
germ cell associated 1
chr9_-_35689913 3.44 ENST00000329305.6
ENST00000645482.3
ENST00000647435.1
ENST00000378292.9
tropomyosin 2
chr5_+_172959416 3.43 ENST00000265100.6
ENST00000519239.5
ribosomal protein L26 like 1
chr19_+_48993864 3.42 ENST00000595090.6
RuvB like AAA ATPase 2
chr17_+_7583828 3.40 ENST00000396501.8
ENST00000250124.11
ENST00000584378.5
ENST00000423172.6
ENST00000579445.5
ENST00000585217.5
ENST00000581380.1
mannose-P-dolichol utilization defect 1
chr6_+_31666056 3.40 ENST00000375882.7
ENST00000375880.6
casein kinase 2 beta
novel protein
chr6_-_31958852 3.39 ENST00000375425.9
ENST00000426722.5
negative elongation factor complex member E
chr16_+_67227105 3.39 ENST00000563953.5
ENST00000304800.14
ENST00000565201.1
transmembrane protein 208
chr5_+_141343818 3.37 ENST00000619750.1
ENST00000253812.8
protocadherin gamma subfamily A, 3
chr5_+_172959511 3.35 ENST00000519522.1
ribosomal protein L26 like 1
chr21_-_35049327 3.35 ENST00000300305.7
RUNX family transcription factor 1
chr14_-_44961889 3.29 ENST00000579157.1
ENST00000396128.9
ENST00000556500.1
kelch like family member 28
chr1_-_109075944 3.28 ENST00000338366.6
TATA-box binding protein associated factor 13
chr4_-_102828048 3.28 ENST00000508249.1
ubiquitin conjugating enzyme E2 D3
chr6_+_111259294 3.27 ENST00000672303.1
ENST00000671876.2
ENST00000368847.5
major facilitator superfamily domain containing 4B
chrX_+_17737443 3.26 ENST00000398080.5
ENST00000380045.7
ENST00000380043.7
ENST00000380041.8
Scm polycomb group protein like 1
chr5_+_83077559 3.26 ENST00000511817.1
X-ray repair cross complementing 4
chr20_+_31547367 3.24 ENST00000394552.3
MCTS family member 2, pseudogene
chr3_-_138174879 3.24 ENST00000260803.9
debranching RNA lariats 1
chr6_+_33391805 3.18 ENST00000428849.7
ENST00000450504.1
kinesin family member C1
chr14_+_69398683 3.17 ENST00000556605.5
ENST00000031146.8
ENST00000336643.10
solute carrier family 39 member 9
chr3_-_197949869 3.17 ENST00000452735.1
ENST00000453254.5
ENST00000455191.5
IQ motif containing G
chr1_-_220272415 3.15 ENST00000358951.7
RAB3 GTPase activating non-catalytic protein subunit 2
chr5_-_37371061 3.15 ENST00000513532.1
ENST00000231498.8
nucleoporin 155
chr19_+_16197900 3.14 ENST00000429941.6
ENST00000291439.8
ENST00000444449.6
ENST00000589822.5
adaptor related protein complex 1 subunit mu 1
chr12_-_6689359 3.14 ENST00000683879.1
zinc finger protein 384
chr10_-_110918934 3.12 ENST00000605742.5
BBSome interacting protein 1
chr7_+_157336961 3.12 ENST00000429029.6
DnaJ heat shock protein family (Hsp40) member B6
chr19_-_18940289 3.09 ENST00000542541.6
ENST00000433218.6
homer scaffold protein 3
chr6_+_33289650 3.07 ENST00000463584.1
prefoldin subunit 6
chr5_+_83077498 3.07 ENST00000282268.7
ENST00000338635.10
ENST00000396027.9
X-ray repair cross complementing 4
chr20_-_49915509 3.06 ENST00000289431.10
spermatogenesis associated 2
chr17_+_35587239 3.05 ENST00000621914.4
ENST00000621668.4
ENST00000616681.4
ENST00000612035.4
ENST00000610402.5
ENST00000614600.4
ENST00000590432.5
ENST00000612116.5
adaptor related protein complex 2 subunit beta 1
chr2_-_25878445 3.04 ENST00000336112.9
ENST00000435504.9
ASXL transcriptional regulator 2

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 13.0 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
3.5 17.4 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
2.9 8.7 GO:0002184 cytoplasmic translational termination(GO:0002184)
2.6 10.2 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
2.3 7.0 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
2.2 13.4 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
2.2 6.5 GO:0044565 dendritic cell proliferation(GO:0044565)
2.1 8.5 GO:1902463 protein localization to cell leading edge(GO:1902463)
2.1 8.5 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
1.8 7.3 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
1.8 5.4 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
1.8 5.4 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
1.8 8.9 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
1.8 5.3 GO:2000793 negative regulation of oxidative phosphorylation uncoupler activity(GO:2000276) cell proliferation involved in heart valve development(GO:2000793)
1.7 7.0 GO:0032641 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) lymphotoxin A production(GO:0032641) positive regulation of mast cell cytokine production(GO:0032765) lymphotoxin A biosynthetic process(GO:0042109)
1.7 8.5 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
1.6 4.9 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
1.6 4.9 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway(GO:2000661)
1.6 4.8 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
1.6 12.8 GO:0051414 response to cortisol(GO:0051414)
1.5 13.4 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
1.4 27.3 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
1.3 4.0 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
1.3 4.0 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
1.3 3.9 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
1.3 3.8 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
1.2 2.5 GO:0006404 RNA import into nucleus(GO:0006404)
1.2 3.6 GO:0097498 endothelial tube lumen extension(GO:0097498)
1.1 5.6 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
1.1 5.6 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
1.1 5.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
1.0 3.1 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
1.0 7.1 GO:0070294 renal sodium ion absorption(GO:0070294)
1.0 3.0 GO:1904933 cardiac right atrium morphogenesis(GO:0003213) mediolateral intercalation(GO:0060031) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775) regulation of cell proliferation in midbrain(GO:1904933)
1.0 13.8 GO:0006930 substrate-dependent cell migration, cell extension(GO:0006930)
1.0 4.9 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.9 2.8 GO:0035048 splicing factor protein import into nucleus(GO:0035048)
0.9 3.7 GO:0034444 negative regulation of lipoprotein oxidation(GO:0034443) regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445)
0.9 12.1 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.9 5.3 GO:0052805 histamine metabolic process(GO:0001692) histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.9 2.6 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.9 6.9 GO:0007144 female meiosis I(GO:0007144)
0.9 2.6 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.9 4.3 GO:0044375 regulation of peroxisome size(GO:0044375)
0.9 3.4 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.8 0.8 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.8 2.5 GO:0090521 regulation of embryonic cell shape(GO:0016476) glomerular visceral epithelial cell migration(GO:0090521)
0.8 2.4 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.8 2.4 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.8 5.6 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.8 6.4 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.8 2.3 GO:0036071 N-glycan fucosylation(GO:0036071)
0.8 2.3 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.7 1.5 GO:0019249 lactate biosynthetic process(GO:0019249)
0.7 9.5 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.7 2.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476)
0.7 6.5 GO:0007135 meiosis II(GO:0007135)
0.7 3.6 GO:0060296 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108) regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.7 2.1 GO:1901253 regulation of intracellular transport of viral material(GO:1901252) negative regulation of intracellular transport of viral material(GO:1901253)
0.7 7.6 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.7 3.4 GO:1904579 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.7 2.7 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.7 2.6 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.6 48.3 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.6 1.9 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.6 1.9 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.6 3.0 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.6 11.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.6 5.9 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.6 3.0 GO:2000870 oocyte growth(GO:0001555) regulation of progesterone secretion(GO:2000870)
0.6 7.5 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.6 13.9 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.6 2.3 GO:0021539 subthalamus development(GO:0021539)
0.6 2.3 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.6 3.4 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.6 2.3 GO:0090301 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of neural crest formation(GO:0090299) negative regulation of neural crest formation(GO:0090301) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.6 4.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.6 19.8 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.6 1.7 GO:0021897 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897)
0.6 1.7 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.6 2.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.5 5.4 GO:0060717 chorion development(GO:0060717)
0.5 2.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.5 1.6 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.5 4.8 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.5 1.6 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.5 4.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.5 3.6 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.5 4.6 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.5 8.5 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.5 3.0 GO:0033504 floor plate development(GO:0033504)
0.5 2.0 GO:0016559 peroxisome fission(GO:0016559)
0.5 6.8 GO:0071285 cellular response to lithium ion(GO:0071285)
0.5 1.5 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.5 2.4 GO:0006041 glucosamine metabolic process(GO:0006041)
0.5 1.9 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.5 3.8 GO:0032790 ribosome disassembly(GO:0032790)
0.5 2.4 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.5 7.6 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.5 4.3 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.5 5.7 GO:0045835 negative regulation of meiotic nuclear division(GO:0045835)
0.5 2.7 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.5 2.3 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.5 1.4 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
0.5 5.0 GO:0019388 galactose catabolic process(GO:0019388)
0.4 1.3 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.4 9.8 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.4 1.8 GO:0035627 ceramide transport(GO:0035627)
0.4 3.5 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.4 3.9 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.4 2.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.4 3.0 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.4 3.0 GO:0032218 riboflavin transport(GO:0032218)
0.4 1.7 GO:1990502 dense core granule maturation(GO:1990502)
0.4 1.2 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.4 1.2 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.4 1.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.4 2.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.4 7.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.4 0.4 GO:0018307 enzyme active site formation(GO:0018307)
0.4 6.6 GO:0003322 pancreatic A cell development(GO:0003322)
0.4 3.5 GO:0006011 UDP-glucose metabolic process(GO:0006011)
0.4 2.3 GO:0031438 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.4 3.8 GO:0002934 desmosome organization(GO:0002934)
0.4 3.0 GO:2000210 positive regulation of anoikis(GO:2000210)
0.4 3.0 GO:0007288 sperm axoneme assembly(GO:0007288)
0.4 8.6 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.4 2.2 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.4 33.4 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.4 1.8 GO:0019348 dolichol metabolic process(GO:0019348)
0.4 1.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.4 4.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.4 1.4 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
0.4 3.5 GO:0032933 SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.3 2.8 GO:0019732 antifungal humoral response(GO:0019732)
0.3 3.8 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.3 12.7 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.3 4.7 GO:0000338 protein deneddylation(GO:0000338)
0.3 4.0 GO:0051665 membrane raft localization(GO:0051665)
0.3 11.2 GO:0031055 chromatin remodeling at centromere(GO:0031055) CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.3 0.3 GO:0021678 fourth ventricle development(GO:0021592) third ventricle development(GO:0021678)
0.3 5.6 GO:0030497 fatty acid elongation(GO:0030497) very long-chain fatty acid biosynthetic process(GO:0042761)
0.3 2.9 GO:0098535 de novo centriole assembly(GO:0098535)
0.3 3.9 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.3 2.2 GO:0051013 microtubule severing(GO:0051013)
0.3 3.5 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.3 1.0 GO:0021764 amygdala development(GO:0021764)
0.3 1.9 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.3 1.0 GO:2000197 regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
0.3 5.0 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.3 6.2 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.3 0.9 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.3 8.7 GO:1904659 hexose transmembrane transport(GO:0035428) glucose transmembrane transport(GO:1904659)
0.3 0.9 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.3 4.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.3 3.8 GO:0035878 nail development(GO:0035878)
0.3 3.8 GO:0022417 protein maturation by protein folding(GO:0022417)
0.3 1.1 GO:0072683 T cell extravasation(GO:0072683)
0.3 3.7 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.3 4.8 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.3 2.0 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.3 4.7 GO:0017004 cytochrome complex assembly(GO:0017004)
0.3 1.7 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.3 1.9 GO:0033183 negative regulation of histone ubiquitination(GO:0033183) histone H2A K63-linked ubiquitination(GO:0070535) negative regulation of protein K63-linked ubiquitination(GO:1900045) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315) negative regulation of protein polyubiquitination(GO:1902915)
0.3 1.1 GO:0033590 response to cobalamin(GO:0033590)
0.3 7.9 GO:0071800 podosome assembly(GO:0071800)
0.3 1.1 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.3 2.4 GO:0006983 ER overload response(GO:0006983)
0.3 1.3 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.3 4.6 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.3 0.5 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792) positive regulation of immature T cell proliferation(GO:0033091)
0.3 7.2 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.3 1.6 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.3 2.8 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.3 0.8 GO:1900127 regulation of hyaluronan biosynthetic process(GO:1900125) positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.3 3.6 GO:0036159 inner dynein arm assembly(GO:0036159)
0.3 4.1 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.3 4.8 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.2 1.5 GO:0031272 pseudopodium assembly(GO:0031269) regulation of pseudopodium assembly(GO:0031272) positive regulation of pseudopodium assembly(GO:0031274)
0.2 2.7 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.2 1.0 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821)
0.2 4.8 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.2 1.0 GO:0006408 snRNA export from nucleus(GO:0006408)
0.2 2.4 GO:0032264 IMP salvage(GO:0032264)
0.2 1.6 GO:0046061 dATP catabolic process(GO:0046061)
0.2 1.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 0.9 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.2 2.0 GO:0033088 regulation of immature T cell proliferation in thymus(GO:0033084) negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.2 0.7 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.2 18.6 GO:0030574 collagen catabolic process(GO:0030574)
0.2 2.6 GO:0071027 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.2 5.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.2 0.6 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.2 4.8 GO:0031167 rRNA methylation(GO:0031167)
0.2 3.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.2 1.4 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 1.2 GO:0061743 motor learning(GO:0061743)
0.2 1.6 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.2 3.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.2 2.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 3.8 GO:0030488 tRNA methylation(GO:0030488)
0.2 2.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.2 1.5 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2 1.7 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.2 5.0 GO:0006829 zinc II ion transport(GO:0006829)
0.2 1.6 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.2 1.1 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.2 1.4 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.2 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039) establishment of protein localization to mitochondrial membrane(GO:0090151)
0.2 0.7 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.2 6.1 GO:0006706 steroid catabolic process(GO:0006706)
0.2 0.9 GO:0035881 amacrine cell differentiation(GO:0035881)
0.2 2.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 6.0 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.2 2.0 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.2 0.5 GO:0032707 negative regulation of interleukin-23 production(GO:0032707)
0.2 0.5 GO:0033512 L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
0.2 0.8 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.2 3.1 GO:0043485 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.2 1.9 GO:0008334 histone mRNA metabolic process(GO:0008334)
0.2 2.0 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 6.8 GO:0008214 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.1 0.4 GO:0038155 interleukin-23-mediated signaling pathway(GO:0038155)
0.1 4.1 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 1.6 GO:0006657 CDP-choline pathway(GO:0006657)
0.1 2.5 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 6.3 GO:0022030 cerebral cortex radial glia guided migration(GO:0021801) telencephalon glial cell migration(GO:0022030)
0.1 3.1 GO:2000144 positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.1 1.0 GO:0009597 detection of virus(GO:0009597)
0.1 0.1 GO:1904204 regulation of skeletal muscle hypertrophy(GO:1904204)
0.1 0.8 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.1 2.0 GO:0035082 axoneme assembly(GO:0035082)
0.1 5.4 GO:0008038 neuron recognition(GO:0008038)
0.1 3.3 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.1 3.4 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.1 10.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.6 GO:0090042 tubulin deacetylation(GO:0090042)
0.1 0.5 GO:2000317 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.1 4.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.7 GO:0071105 response to interleukin-11(GO:0071105)
0.1 0.6 GO:0016240 autophagosome docking(GO:0016240)
0.1 1.1 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.1 3.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.6 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.1 1.8 GO:0006020 inositol metabolic process(GO:0006020)
0.1 0.6 GO:0016584 nucleosome positioning(GO:0016584)
0.1 2.4 GO:0007176 regulation of epidermal growth factor-activated receptor activity(GO:0007176)
0.1 0.6 GO:0021997 neural plate axis specification(GO:0021997)
0.1 1.0 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 1.5 GO:0045116 protein neddylation(GO:0045116)
0.1 1.5 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1 0.9 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 2.8 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.1 3.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 1.5 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.1 0.4 GO:2000152 regulation of ubiquitin-specific protease activity(GO:2000152) positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.3 GO:0034770 histone H4-K20 methylation(GO:0034770)
0.1 5.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.1 4.5 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 3.1 GO:0050873 brown fat cell differentiation(GO:0050873)
0.1 15.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.8 GO:0002467 germinal center formation(GO:0002467)
0.1 1.8 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 2.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 0.8 GO:0000154 rRNA modification(GO:0000154)
0.1 1.4 GO:0045109 intermediate filament organization(GO:0045109)
0.1 1.6 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 1.7 GO:0030539 male genitalia development(GO:0030539)
0.1 0.4 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.1 0.3 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.1 0.3 GO:0030035 microspike assembly(GO:0030035)
0.1 0.1 GO:0000478 cleavage involved in rRNA processing(GO:0000469) endonucleolytic cleavage involved in rRNA processing(GO:0000478)
0.1 1.6 GO:2000036 regulation of stem cell population maintenance(GO:2000036)
0.1 2.9 GO:0015813 L-glutamate transport(GO:0015813)
0.1 1.5 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 0.8 GO:0044827 modulation by host of viral genome replication(GO:0044827)
0.1 1.6 GO:0070987 error-free translesion synthesis(GO:0070987)
0.1 1.6 GO:0051444 negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.1 6.4 GO:0030521 androgen receptor signaling pathway(GO:0030521)
0.1 1.0 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.1 0.6 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.2 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.1 2.2 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.1 0.2 GO:0098507 polynucleotide 5' dephosphorylation(GO:0098507)
0.1 0.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.7 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.1 1.3 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.1 3.2 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.1 1.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.1 1.4 GO:0035635 entry of bacterium into host cell(GO:0035635)
0.1 1.3 GO:0034389 lipid particle organization(GO:0034389)
0.1 6.2 GO:0070268 cornification(GO:0070268)
0.1 1.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.1 1.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.5 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 1.8 GO:0051123 RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.1 2.9 GO:0042073 intraciliary transport(GO:0042073)
0.1 1.0 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.1 0.7 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.2 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 7.2 GO:0046546 male gonad development(GO:0008584) development of primary male sexual characteristics(GO:0046546)
0.1 0.4 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 4.5 GO:0007286 spermatid development(GO:0007286)
0.1 3.4 GO:0033275 muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1 2.2 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 3.6 GO:0007338 single fertilization(GO:0007338)
0.0 1.9 GO:0006110 regulation of glycolytic process(GO:0006110)
0.0 1.4 GO:0006400 tRNA modification(GO:0006400)
0.0 1.2 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 1.8 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 1.6 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.3 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.0 3.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 2.2 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.7 GO:0006903 vesicle targeting(GO:0006903)
0.0 2.0 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.0 0.9 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.4 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.2 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.9 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.0 1.4 GO:0045815 positive regulation of gene expression, epigenetic(GO:0045815)
0.0 0.3 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.3 GO:0055129 proline biosynthetic process(GO:0006561) L-proline biosynthetic process(GO:0055129)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.8 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.3 GO:0002031 G-protein coupled receptor internalization(GO:0002031)
0.0 1.2 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 1.1 GO:0031397 negative regulation of protein ubiquitination(GO:0031397)
0.0 0.6 GO:0050667 homocysteine metabolic process(GO:0050667)
0.0 0.2 GO:0043570 maintenance of DNA repeat elements(GO:0043570)
0.0 0.3 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 2.3 GO:0043473 pigmentation(GO:0043473)
0.0 5.5 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.9 GO:0060976 coronary vasculature development(GO:0060976)
0.0 2.8 GO:0090630 activation of GTPase activity(GO:0090630)
0.0 0.7 GO:0090314 positive regulation of protein targeting to membrane(GO:0090314)
0.0 0.7 GO:0060080 inhibitory postsynaptic potential(GO:0060080)
0.0 0.3 GO:0099517 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 1.1 GO:0006284 base-excision repair(GO:0006284)
0.0 0.2 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.2 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.5 GO:0030890 positive regulation of B cell proliferation(GO:0030890)
0.0 0.9 GO:0006692 prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0 0.7 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.6 GO:0046039 GTP metabolic process(GO:0046039)
0.0 0.9 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 1.8 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 1.5 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.5 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.3 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 4.3 GO:0006936 muscle contraction(GO:0006936)
0.0 0.5 GO:1901185 negative regulation of ERBB signaling pathway(GO:1901185)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 15.6 GO:0032449 CBM complex(GO:0032449)
2.9 8.7 GO:0018444 translation release factor complex(GO:0018444)
2.3 11.6 GO:0070847 core mediator complex(GO:0070847)
2.2 6.5 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
2.0 10.2 GO:0097149 centralspindlin complex(GO:0097149)
1.8 20.0 GO:0033588 Elongator holoenzyme complex(GO:0033588)
1.8 5.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
1.8 17.8 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
1.7 8.3 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
1.4 18.6 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
1.3 11.8 GO:0032133 chromosome passenger complex(GO:0032133)
1.3 3.9 GO:1902737 dendritic filopodium(GO:1902737)
1.3 12.9 GO:0071439 clathrin complex(GO:0071439)
1.2 16.0 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
1.1 7.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
1.0 3.1 GO:0044611 nuclear pore inner ring(GO:0044611)
1.0 3.1 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
1.0 7.2 GO:0032021 NELF complex(GO:0032021)
1.0 3.9 GO:0008537 proteasome activator complex(GO:0008537)
1.0 9.7 GO:0031595 nuclear proteasome complex(GO:0031595)
1.0 7.6 GO:0034464 BBSome(GO:0034464)
0.9 3.7 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.9 2.7 GO:0034515 proteasome storage granule(GO:0034515)
0.9 26.1 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.9 8.0 GO:0033391 chromatoid body(GO:0033391)
0.9 3.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.9 3.5 GO:0070435 Shc-EGFR complex(GO:0070435)
0.9 4.3 GO:0031673 H zone(GO:0031673)
0.8 15.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.8 8.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.8 4.5 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.8 3.8 GO:1990425 terminal cisterna(GO:0014802) ryanodine receptor complex(GO:1990425)
0.7 7.2 GO:0097255 R2TP complex(GO:0097255)
0.7 2.8 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.7 13.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.6 2.4 GO:0071920 cleavage body(GO:0071920)
0.6 24.3 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.6 1.8 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.6 6.5 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.6 5.6 GO:0043203 axon hillock(GO:0043203)
0.5 2.7 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.5 3.7 GO:1990745 EARP complex(GO:1990745)
0.5 3.2 GO:0002177 manchette(GO:0002177)
0.5 5.3 GO:0000439 core TFIIH complex(GO:0000439)
0.5 11.2 GO:0030128 clathrin coat of endocytic vesicle(GO:0030128)
0.5 4.5 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.5 6.0 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.5 4.4 GO:0072546 ER membrane protein complex(GO:0072546)
0.5 1.5 GO:0070939 Dsl1p complex(GO:0070939)
0.5 3.4 GO:0031298 replication fork protection complex(GO:0031298)
0.4 1.3 GO:0034455 t-UTP complex(GO:0034455)
0.4 12.5 GO:0002080 acrosomal membrane(GO:0002080)
0.4 4.0 GO:0070765 gamma-secretase complex(GO:0070765)
0.4 23.8 GO:0002102 podosome(GO:0002102)
0.4 1.3 GO:0033263 CORVET complex(GO:0033263)
0.4 11.6 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.4 6.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.4 5.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.4 2.3 GO:0071797 LUBAC complex(GO:0071797)
0.4 2.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.4 2.6 GO:0016272 prefoldin complex(GO:0016272)
0.3 3.7 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.3 3.0 GO:0097443 sorting endosome(GO:0097443)
0.3 0.9 GO:0071817 MMXD complex(GO:0071817)
0.3 1.3 GO:0005899 insulin receptor complex(GO:0005899)
0.3 3.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.3 4.3 GO:0000124 SAGA complex(GO:0000124)
0.3 4.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.3 4.6 GO:0034709 methylosome(GO:0034709)
0.3 32.0 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.3 0.8 GO:0098536 deuterosome(GO:0098536)
0.3 3.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.3 2.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.3 4.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 2.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.2 1.0 GO:0005846 nuclear cap binding complex(GO:0005846)
0.2 7.2 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 4.9 GO:0044447 axoneme part(GO:0044447)
0.2 1.1 GO:0089701 U2AF(GO:0089701)
0.2 2.4 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.2 16.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 2.5 GO:0005869 dynactin complex(GO:0005869)
0.2 7.8 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 6.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 2.1 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.2 1.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.2 1.6 GO:0032797 SMN complex(GO:0032797)
0.2 0.5 GO:1902636 kinociliary basal body(GO:1902636)
0.2 2.3 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.2 3.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.2 1.5 GO:0042382 paraspeckles(GO:0042382)
0.2 1.4 GO:0000796 condensin complex(GO:0000796)
0.2 3.4 GO:0030686 90S preribosome(GO:0030686)
0.2 1.9 GO:0070449 elongin complex(GO:0070449)
0.2 1.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.2 4.9 GO:0030057 desmosome(GO:0030057)
0.2 8.3 GO:0008180 COP9 signalosome(GO:0008180)
0.2 4.2 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2 1.1 GO:0043196 varicosity(GO:0043196)
0.1 0.4 GO:0072536 interleukin-23 receptor complex(GO:0072536)
0.1 1.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 1.6 GO:0042587 glycogen granule(GO:0042587)
0.1 0.4 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.1 0.7 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.1 5.6 GO:0032420 stereocilium(GO:0032420)
0.1 2.5 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.9 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588) box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.1 10.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.8 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 2.1 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.1 0.6 GO:0032302 MutSbeta complex(GO:0032302)
0.1 6.0 GO:0005871 kinesin complex(GO:0005871)
0.1 0.8 GO:1990130 GATOR2 complex(GO:0061700) Iml1 complex(GO:1990130)
0.1 3.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 4.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.1 5.4 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.6 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 11.0 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.3 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.6 GO:0032059 bleb(GO:0032059)
0.1 3.0 GO:0005581 collagen trimer(GO:0005581)
0.1 5.2 GO:0005844 polysome(GO:0005844)
0.1 3.2 GO:0016592 mediator complex(GO:0016592)
0.1 2.6 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.1 1.1 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 1.6 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 1.9 GO:0005839 proteasome core complex(GO:0005839)
0.1 9.0 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.1 2.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 5.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.3 GO:0032044 DSIF complex(GO:0032044)
0.1 6.6 GO:0000779 condensed chromosome, centromeric region(GO:0000779)
0.1 1.5 GO:0000421 autophagosome membrane(GO:0000421)
0.1 6.6 GO:0031514 motile cilium(GO:0031514)
0.1 2.2 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 3.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 1.3 GO:0001533 cornified envelope(GO:0001533)
0.1 3.0 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.1 9.8 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.1 2.1 GO:0034451 centriolar satellite(GO:0034451)
0.1 1.1 GO:0005922 connexon complex(GO:0005922)
0.1 3.5 GO:0048786 presynaptic active zone(GO:0048786)
0.1 3.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 2.0 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.1 1.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.1 1.2 GO:0031082 BLOC complex(GO:0031082)
0.1 3.1 GO:0045178 basal part of cell(GO:0045178)
0.1 6.3 GO:0000922 spindle pole(GO:0000922)
0.1 9.4 GO:0030018 Z disc(GO:0030018)
0.1 0.6 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 14.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.2 GO:1990131 EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 1.7 GO:0016235 aggresome(GO:0016235)
0.0 2.1 GO:0005795 Golgi stack(GO:0005795)
0.0 2.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.7 GO:0005685 U1 snRNP(GO:0005685)
0.0 4.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.4 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.5 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.0 1.7 GO:0005875 microtubule associated complex(GO:0005875)
0.0 0.7 GO:0031941 filamentous actin(GO:0031941)
0.0 0.7 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 2.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.0 0.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 2.7 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 8.5 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 0.7 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.4 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0005854 nascent polypeptide-associated complex(GO:0005854)
0.0 0.5 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 1.0 GO:0005771 multivesicular body(GO:0005771)
0.0 1.0 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 3.2 GO:0001726 ruffle(GO:0001726)
0.0 4.5 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 0.2 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.3 GO:0005859 muscle myosin complex(GO:0005859)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 13.4 GO:0004146 dihydrofolate reductase activity(GO:0004146)
3.0 27.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
1.9 5.6 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
1.9 5.6 GO:0080023 3R-hydroxyacyl-CoA dehydratase activity(GO:0080023)
1.8 8.9 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
1.6 4.9 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
1.6 4.8 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
1.5 6.1 GO:0004773 steryl-sulfatase activity(GO:0004773)
1.5 5.9 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
1.5 10.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
1.3 4.0 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
1.3 5.3 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
1.3 11.8 GO:0035174 histone serine kinase activity(GO:0035174)
1.2 4.9 GO:0004909 interleukin-1, Type I, activating receptor activity(GO:0004909)
1.0 4.0 GO:0032810 sterol response element binding(GO:0032810)
1.0 3.0 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
1.0 13.9 GO:0032050 clathrin heavy chain binding(GO:0032050)
1.0 5.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.9 5.6 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.9 4.5 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.9 1.8 GO:0097001 ceramide binding(GO:0097001)
0.9 5.2 GO:0070004 cysteine-type carboxypeptidase activity(GO:0016807) cysteine-type exopeptidase activity(GO:0070004)
0.9 6.8 GO:0019237 centromeric DNA binding(GO:0019237)
0.9 6.0 GO:0048408 epidermal growth factor binding(GO:0048408)
0.8 2.3 GO:0046921 glycoprotein 6-alpha-L-fucosyltransferase activity(GO:0008424) alpha-(1->6)-fucosyltransferase activity(GO:0046921)
0.7 8.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.7 2.2 GO:0001034 RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.7 2.2 GO:0003896 DNA primase activity(GO:0003896)
0.7 9.2 GO:0019966 interleukin-1 binding(GO:0019966)
0.7 6.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.7 18.8 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.7 2.0 GO:0052816 medium-chain acyl-CoA hydrolase activity(GO:0052815) long-chain acyl-CoA hydrolase activity(GO:0052816)
0.7 4.0 GO:0034511 U3 snoRNA binding(GO:0034511)
0.7 2.6 GO:0034353 RNA pyrophosphohydrolase activity(GO:0034353)
0.7 3.9 GO:0034046 poly(G) binding(GO:0034046)
0.6 9.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.6 13.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.6 1.8 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.6 1.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.6 4.5 GO:0098821 BMP receptor activity(GO:0098821)
0.6 4.0 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.6 3.9 GO:0061133 endopeptidase activator activity(GO:0061133)
0.5 1.6 GO:0044714 GTP diphosphatase activity(GO:0036219) 2-hydroxy-adenosine triphosphate pyrophosphatase activity(GO:0044713) 2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity(GO:0044714) ATP diphosphatase activity(GO:0047693)
0.5 10.7 GO:0005522 profilin binding(GO:0005522)
0.5 2.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.5 3.6 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.5 8.6 GO:0042809 vitamin D receptor binding(GO:0042809)
0.5 1.5 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.5 10.9 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.5 13.8 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.5 4.8 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.5 1.9 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.5 7.0 GO:0015643 toxic substance binding(GO:0015643)
0.5 19.4 GO:0017091 AU-rich element binding(GO:0017091)
0.4 8.5 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.4 2.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.4 2.2 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.4 2.2 GO:0003796 lysozyme activity(GO:0003796)
0.4 3.0 GO:0032217 riboflavin transporter activity(GO:0032217)
0.4 2.5 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.4 1.2 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.4 3.7 GO:0001056 RNA polymerase III activity(GO:0001056)
0.4 1.6 GO:0004461 lactose synthase activity(GO:0004461)
0.4 15.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.4 2.4 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.4 3.6 GO:0004565 beta-galactosidase activity(GO:0004565)
0.4 11.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.4 6.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.4 2.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.4 5.7 GO:0003993 acid phosphatase activity(GO:0003993)
0.4 2.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.4 38.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.4 1.5 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.4 2.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.3 3.5 GO:0004064 arylesterase activity(GO:0004064)
0.3 3.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.3 2.1 GO:0051373 FATZ binding(GO:0051373)
0.3 4.4 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 5.0 GO:0004985 opioid receptor activity(GO:0004985)
0.3 1.3 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.3 2.3 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.3 1.3 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.3 2.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.3 1.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.3 1.6 GO:0004974 leukotriene receptor activity(GO:0004974)
0.3 3.2 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.3 4.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.3 2.7 GO:0016015 morphogen activity(GO:0016015)
0.3 8.7 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.3 3.8 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.3 0.9 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.3 2.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.3 1.4 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.3 3.8 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.3 1.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.3 21.7 GO:0003777 microtubule motor activity(GO:0003777)
0.3 2.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.3 0.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.3 15.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.3 5.8 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.2 3.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 1.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 3.8 GO:0048185 calcium channel inhibitor activity(GO:0019855) activin binding(GO:0048185)
0.2 1.5 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.2 7.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.2 1.7 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.2 3.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 1.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.2 4.5 GO:0008494 translation activator activity(GO:0008494)
0.2 0.8 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.2 1.0 GO:0051998 carboxyl-O-methyltransferase activity(GO:0010340) protein carboxyl O-methyltransferase activity(GO:0051998)
0.2 8.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 3.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.2 8.3 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.2 1.9 GO:1901612 cardiolipin binding(GO:1901612)
0.2 8.5 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 2.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.2 2.6 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 0.9 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.2 4.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.2 3.6 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 3.1 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.2 11.9 GO:0070888 E-box binding(GO:0070888)
0.2 2.6 GO:0030215 semaphorin receptor binding(GO:0030215)
0.2 1.0 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.2 1.9 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.2 1.6 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.2 1.4 GO:0004969 histamine receptor activity(GO:0004969)
0.2 2.2 GO:0042577 lipid phosphatase activity(GO:0042577)
0.2 0.9 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.6 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.4 GO:0042019 interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020)
0.1 1.7 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.1 0.7 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.1 0.7 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 3.0 GO:0048018 receptor agonist activity(GO:0048018)
0.1 8.1 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 3.6 GO:0005523 tropomyosin binding(GO:0005523)
0.1 6.4 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.9 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 1.7 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.3 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543) peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 23.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 0.5 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 4.4 GO:0001671 ATPase activator activity(GO:0001671)
0.1 2.0 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.0 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 0.6 GO:0019826 oxygen sensor activity(GO:0019826)
0.1 3.1 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 5.9 GO:0070063 RNA polymerase binding(GO:0070063)
0.1 2.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 1.4 GO:0070628 proteasome binding(GO:0070628)
0.1 3.2 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.7 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.3 GO:0030515 snoRNA binding(GO:0030515)
0.1 0.5 GO:0016748 succinyltransferase activity(GO:0016748)
0.1 1.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.7 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.4 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 0.8 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.1 0.6 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.1 1.0 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.1 2.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 6.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.1 3.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 2.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 1.1 GO:0033612 receptor serine/threonine kinase binding(GO:0033612)
0.1 5.0 GO:0051087 chaperone binding(GO:0051087)
0.1 0.2 GO:0000406 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.1 0.5 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.1 2.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 7.0 GO:0008013 beta-catenin binding(GO:0008013)
0.1 6.0 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.6 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.1 0.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.1 1.8 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters(GO:0016891)
0.1 0.6 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 2.2 GO:0003678 DNA helicase activity(GO:0003678)
0.1 0.5 GO:0032052 bile acid binding(GO:0032052)
0.1 3.6 GO:0004527 exonuclease activity(GO:0004527)
0.1 12.3 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 0.1 GO:1903136 cuprous ion binding(GO:1903136)
0.1 0.7 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 1.3 GO:0071949 FAD binding(GO:0071949)
0.0 0.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 3.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.7 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 1.4 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 1.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 1.3 GO:0019239 deaminase activity(GO:0019239)
0.0 0.8 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.4 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 1.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 3.7 GO:0005319 lipid transporter activity(GO:0005319)
0.0 2.8 GO:0005518 collagen binding(GO:0005518)
0.0 1.9 GO:0005262 calcium channel activity(GO:0005262)
0.0 22.4 GO:0005509 calcium ion binding(GO:0005509)
0.0 4.9 GO:0008083 growth factor activity(GO:0008083)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 4.8 GO:0035091 phosphatidylinositol binding(GO:0035091)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 6.5 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 1.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.5 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.7 GO:0043531 ADP binding(GO:0043531)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.5 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.9 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 1.1 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.1 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.3 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.7 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.5 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding(GO:0000980)
0.0 0.3 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 25.4 PID ARF 3PATHWAY Arf1 pathway
0.6 17.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.5 25.1 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.5 15.3 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.4 26.1 PID AURORA B PATHWAY Aurora B signaling
0.3 18.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.3 7.0 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.3 14.1 PID AURORA A PATHWAY Aurora A signaling
0.3 6.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 6.0 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.2 11.0 PID MYC PATHWAY C-MYC pathway
0.2 12.1 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.2 8.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.2 13.7 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 6.8 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.2 3.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.2 3.6 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.2 4.0 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.2 1.3 PID INSULIN PATHWAY Insulin Pathway
0.2 2.7 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.1 4.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.1 11.9 PID AP1 PATHWAY AP-1 transcription factor network
0.1 3.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 3.7 PID ALK1 PATHWAY ALK1 signaling events
0.1 8.1 PID BMP PATHWAY BMP receptor signaling
0.1 2.6 PID IL1 PATHWAY IL1-mediated signaling events
0.1 6.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 2.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 4.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 0.7 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.1 3.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 0.7 PID TNF PATHWAY TNF receptor signaling pathway
0.1 1.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 3.7 ST P38 MAPK PATHWAY p38 MAPK Pathway
0.1 2.6 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 3.1 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 4.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 2.3 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 3.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.1 0.8 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 0.7 PID BARD1 PATHWAY BARD1 signaling events
0.1 11.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.1 1.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.0 PID PLK1 PATHWAY PLK1 signaling events
0.0 1.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 2.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.2 PID CD40 PATHWAY CD40/CD40L signaling
0.0 2.2 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 3.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 5.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.9 PID ENDOTHELIN PATHWAY Endothelins
0.0 2.3 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 6.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.6 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.4 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.3 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.5 PID TGFBR PATHWAY TGF-beta receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 17.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.9 22.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.8 21.0 REACTOME KINESINS Genes involved in Kinesins
0.6 8.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.5 2.4 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.5 6.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.5 10.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.4 8.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.4 5.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.3 3.7 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.3 5.8 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.3 4.0 REACTOME SIGNALING BY NOTCH3 Genes involved in Signaling by NOTCH3
0.3 1.5 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.3 11.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.3 6.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 18.9 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.3 4.5 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.3 10.7 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.3 6.2 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.3 13.3 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.3 9.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.3 4.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.3 10.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.3 25.4 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.3 4.6 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.3 7.8 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.2 2.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.2 2.6 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.2 6.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.2 2.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.2 8.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.2 2.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.2 8.1 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.2 3.0 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.2 8.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.2 3.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.2 7.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.2 2.3 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
0.2 4.0 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 12.0 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 3.9 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 1.7 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 2.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 6.4 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.1 5.0 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 4.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 1.9 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 2.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.1 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 7.2 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.1 0.9 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.1 REACTOME SIGNALING BY TGF BETA RECEPTOR COMPLEX Genes involved in Signaling by TGF-beta Receptor Complex
0.1 4.1 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.1 28.5 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.1 1.6 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 1.6 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.1 1.5 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.1 0.9 REACTOME TRANSCRIPTION COUPLED NER TC NER Genes involved in Transcription-coupled NER (TC-NER)
0.1 1.1 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
0.1 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.1 3.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 1.1 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 1.6 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 3.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.0 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 0.3 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1 5.2 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.1 3.1 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.1 1.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.7 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.7 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 1.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 2.4 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation
0.0 1.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.5 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 0.7 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.8 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 3.3 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.2 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 1.0 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 3.5 REACTOME APOPTOSIS Genes involved in Apoptosis
0.0 0.6 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation