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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for ETV6

Z-value: 6.63

Motif logo

Transcription factors associated with ETV6

Gene Symbol Gene ID Gene Info
ENSG00000139083.11 ETV6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ETV6hg38_v1_chr12_+_11649666_11649751-0.243.9e-04Click!

Activity profile of ETV6 motif

Sorted Z-values of ETV6 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of ETV6

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr5_+_168486462 62.13 ENST00000231572.8
ENST00000626454.1
arginyl-tRNA synthetase 1
chr2_+_65227792 42.09 ENST00000260641.10
ENST00000377982.8
actin related protein 2
chr8_-_54101855 30.59 ENST00000522007.5
ENST00000521898.5
ENST00000316963.8
ENST00000518546.5
lysophospholipase 1
chr1_+_203861575 30.31 ENST00000414487.7
small nuclear ribonucleoprotein polypeptide E
chr11_+_66002754 29.67 ENST00000527348.1
BAF nuclear assembly factor 1
chr11_+_66002225 29.17 ENST00000445560.6
ENST00000530204.1
BAF nuclear assembly factor 1
chr11_+_66002475 28.15 ENST00000312175.7
ENST00000533166.5
BAF nuclear assembly factor 1
chr2_+_121737100 27.62 ENST00000455432.5
translin
chr2_-_96305521 27.60 ENST00000323853.10
small nuclear ribonucleoprotein U5 subunit 200
chr20_-_50958520 25.62 ENST00000371588.10
ENST00000371584.9
ENST00000413082.1
ENST00000371582.8
dolichyl-phosphate mannosyltransferase subunit 1, catalytic
chr2_+_201071984 25.16 ENST00000237889.9
ENST00000433898.5
ENST00000684175.1
ENST00000682325.1
ENST00000454214.1
ENST00000684420.1
NADH:ubiquinone oxidoreductase subunit B3
chr8_-_116755784 23.73 ENST00000518949.5
ENST00000522453.1
ENST00000518995.5
ENST00000521861.6
ENST00000611080.1
eukaryotic translation initiation factor 3 subunit H
chr1_-_149927756 23.66 ENST00000271628.9
splicing factor 3b subunit 4
chr3_+_52705828 23.35 ENST00000233025.11
signal peptidase complex subunit 1
chr12_+_10505602 23.23 ENST00000322446.3
eukaryotic translation initiation factor 2 subunit gamma B
chr15_-_65517244 23.19 ENST00000341861.9
dipeptidyl peptidase 8
chr22_+_40346508 22.98 ENST00000636714.1
ENST00000216194.11
ENST00000623978.3
ENST00000636265.1
ENST00000680378.1
adenylosuccinate lyase
chr15_-_84716063 22.17 ENST00000558217.5
ENST00000558196.1
ENST00000558134.5
SEC11 homolog A, signal peptidase complex subunit
chr3_+_128052390 22.13 ENST00000481210.5
ENST00000243253.8
SEC61 translocon subunit alpha 1
chr15_-_84716099 21.74 ENST00000560266.5
SEC11 homolog A, signal peptidase complex subunit
chr1_+_84479239 21.45 ENST00000370656.5
ENST00000370654.6
ribosome production factor 1 homolog
chr20_-_35284745 21.31 ENST00000374443.7
ENST00000374450.8
eukaryotic translation initiation factor 6
chr15_-_65517653 21.28 ENST00000559526.5
ENST00000358939.8
ENST00000560665.1
ENST00000300141.11
dipeptidyl peptidase 8
chr8_-_120445092 21.09 ENST00000518918.1
mitochondrial ribosomal protein L13
chr20_+_16729961 21.03 ENST00000377943.9
ENST00000246071.8
small nuclear ribonucleoprotein polypeptide B2
chr19_+_1067272 21.02 ENST00000590214.5
Rho GTPase activating protein 45
chr20_-_35284715 20.85 ENST00000374436.7
ENST00000675032.1
eukaryotic translation initiation factor 6
chr7_+_99408958 20.81 ENST00000222969.10
BUD31 homolog
chr1_-_150234668 20.61 ENST00000616917.4
acidic nuclear phosphoprotein 32 family member E
chr15_-_84716129 20.20 ENST00000268220.12
SEC11 homolog A, signal peptidase complex subunit
chr15_-_84716153 19.95 ENST00000455959.7
SEC11 homolog A, signal peptidase complex subunit
chr19_+_1067493 19.92 ENST00000586866.5
Rho GTPase activating protein 45
chr19_+_48993864 19.92 ENST00000595090.6
RuvB like AAA ATPase 2
chr14_+_34982674 19.78 ENST00000554803.5
ENST00000546080.6
ENST00000555746.6
ENST00000678963.1
signal recognition particle 54
chr7_+_99408609 19.75 ENST00000403633.6
BUD31 homolog
chr3_-_49104745 19.70 ENST00000635194.1
ENST00000306125.12
ENST00000634602.1
ENST00000414533.5
ENST00000635443.1
ENST00000452739.5
ENST00000635231.1
glutaminyl-tRNA synthetase 1
chrX_+_24054931 19.65 ENST00000253039.9
ENST00000423068.1
eukaryotic translation initiation factor 2 subunit gamma
chr8_-_123042122 19.43 ENST00000405944.7
derlin 1
chr19_+_1067144 19.17 ENST00000313093.7
Rho GTPase activating protein 45
chr15_-_65517704 19.13 ENST00000321147.10
dipeptidyl peptidase 8
chr3_-_49104457 19.02 ENST00000635292.1
ENST00000635541.1
ENST00000464962.6
glutaminyl-tRNA synthetase 1
chr1_-_165768835 18.95 ENST00000481278.5
transmembrane and coiled-coil domains 1
chr8_-_54101777 18.55 ENST00000343231.10
lysophospholipase 1
chr3_-_10321041 18.08 ENST00000397109.7
ENST00000428626.5
ENST00000445064.1
ENST00000431352.1
ENST00000397117.5
ENST00000337354.8
ENST00000383801.6
ENST00000432213.1
ENST00000350697.8
SEC13 homolog, nuclear pore and COPII coat complex component
chrX_+_70290077 17.71 ENST00000374403.4
kinesin family member 4A
chr9_-_2844058 17.56 ENST00000397885.3
pumilio RNA binding family member 3
chr15_-_84716384 17.31 ENST00000559729.5
SEC11 homolog A, signal peptidase complex subunit
chr11_-_6612141 17.22 ENST00000527248.2
ENST00000299424.9
TATA-box binding protein associated factor 10
chr16_+_74296789 17.04 ENST00000219313.9
ENST00000567958.5
ENST00000568615.2
proteasome 26S subunit, non-ATPase 7
chr3_+_52706092 16.84 ENST00000619898.5
signal peptidase complex subunit 1
chr6_-_13814490 16.79 ENST00000379170.8
mitochondrial calcium uniporter regulator 1
chr7_-_54759182 16.78 ENST00000450622.1
ENST00000352861.9
ENST00000395535.7
SEC61 translocon subunit gamma
chr8_-_130016414 16.76 ENST00000401979.6
ENST00000517654.5
ENST00000522361.1
ENST00000518167.5
CYFIP related Rac1 interactor B
chr13_+_28659100 16.68 ENST00000460403.1
ENST00000380842.5
proteasome maturation protein
chr2_+_201116793 16.57 ENST00000441224.5
CASP8 and FADD like apoptosis regulator
chr14_+_34982963 16.52 ENST00000678627.1
ENST00000216774.11
ENST00000555557.5
signal recognition particle 54
chr2_+_65228122 16.34 ENST00000542850.2
actin related protein 2
chr22_+_40346461 16.25 ENST00000623632.4
ENST00000625194.4
ENST00000637666.2
ENST00000680978.1
ENST00000623063.3
ENST00000679723.1
ENST00000342312.9
adenylosuccinate lyase
chr11_+_47579029 16.17 ENST00000529276.1
ENST00000528192.5
ENST00000530295.5
ENST00000534208.5
ENST00000263774.9
NADH:ubiquinone oxidoreductase core subunit S3
chr10_+_42782769 15.89 ENST00000374518.6
BMS1 ribosome biogenesis factor
chr11_-_73982830 15.89 ENST00000536983.5
ENST00000663595.2
ENST00000310473.9
uncoupling protein 2
chr14_+_55051639 15.81 ENST00000395468.9
ENST00000622254.1
mitogen-activated protein kinase 1 interacting protein 1 like
chr14_+_93207229 15.80 ENST00000554232.5
ENST00000556871.5
ENST00000013070.11
ENST00000555113.5
ubiquitin protein ligase E3 component n-recognin 7
chr3_-_196942377 15.79 ENST00000447325.5
nuclear cap binding protein subunit 2
chr7_+_100884974 15.74 ENST00000448764.5
serrate, RNA effector molecule
chr8_-_54101979 15.59 ENST00000618914.4
lysophospholipase 1
chr19_-_9435490 15.47 ENST00000592292.5
ENST00000588221.5
zinc finger protein 266
chr14_-_21383989 15.41 ENST00000216297.7
SPT16 homolog, facilitates chromatin remodeling subunit
chr19_-_9435551 15.40 ENST00000651268.1
ENST00000592904.7
zinc finger protein 266
chr19_+_55386338 15.39 ENST00000558131.1
ENST00000558752.1
ribosomal protein L28
chr11_+_59142728 15.15 ENST00000528737.5
FAM111 trypsin like peptidase A
chr8_-_47960126 14.83 ENST00000314191.7
ENST00000338368.7
protein kinase, DNA-activated, catalytic subunit
chr21_-_44920855 14.83 ENST00000397854.7
integrin subunit beta 2
chr3_-_16513643 14.69 ENST00000334133.9
raftlin, lipid raft linker 1
chr8_-_120445140 14.68 ENST00000306185.8
mitochondrial ribosomal protein L13
chr5_+_36151989 14.63 ENST00000274254.9
S-phase kinase associated protein 2
chr14_+_20989968 14.36 ENST00000382985.8
ENST00000339374.11
ENST00000556670.6
ENST00000553564.5
ENST00000554751.5
ENST00000554283.1
ENST00000555670.1
methyltransferase like 17
chr19_-_10119886 14.33 ENST00000587146.5
ENST00000253108.9
ENST00000588709.5
eukaryotic translation initiation factor 3 subunit G
chr1_+_151399557 14.29 ENST00000290541.7
proteasome 20S subunit beta 4
chr1_-_19485502 14.19 ENST00000264203.7
ENST00000375144.6
ENST00000674432.1
ENST00000264202.8
capping actin protein of muscle Z-line subunit beta
chr21_-_44920892 14.17 ENST00000397846.7
ENST00000652462.1
ENST00000302347.10
ENST00000524251.1
integrin subunit beta 2
chr5_-_31532039 14.16 ENST00000511367.6
ENST00000344624.8
ENST00000513349.5
drosha ribonuclease III
chr11_-_57335854 14.02 ENST00000529002.2
ENST00000278412.7
structure specific recognition protein 1
chr19_-_58554960 13.92 ENST00000596708.1
ENST00000601220.5
ENST00000597848.1
charged multivesicular body protein 2A
chr20_+_2840694 13.84 ENST00000380469.7
ENST00000380445.8
ENST00000453689.5
ENST00000417508.1
VPS16 core subunit of CORVET and HOPS complexes
chr19_-_12933680 13.84 ENST00000593021.1
ENST00000314606.9
ENST00000587981.1
ENST00000423140.6
phenylalanyl-tRNA synthetase subunit alpha
chr1_+_26317950 13.63 ENST00000374213.3
CD52 molecule
chr11_-_60906564 13.59 ENST00000541371.5
ENST00000227524.9
pre-mRNA processing factor 19
chr19_-_10403508 13.50 ENST00000589629.5
ENST00000222005.7
cell division cycle 37, HSP90 cochaperone
chr7_+_44200960 13.44 ENST00000496112.5
ENST00000678359.1
ENST00000223369.3
ENST00000677090.1
YKT6 v-SNARE homolog
chr11_+_59142811 13.40 ENST00000676459.1
ENST00000675163.1
ENST00000684135.1
ENST00000682018.1
ENST00000675806.2
ENST00000529985.3
ENST00000676340.1
ENST00000674617.1
FAM111 trypsin like peptidase A
chr8_-_130016395 13.38 ENST00000523509.5
CYFIP related Rac1 interactor B
chr15_-_64989894 13.38 ENST00000416889.6
ENST00000204566.7
SPG21 abhydrolase domain containing, maspardin
chr16_-_69339493 13.25 ENST00000562595.5
ENST00000615447.1
ENST00000306875.10
ENST00000562081.2
component of oligomeric golgi complex 8
chr19_-_10119863 13.22 ENST00000589454.5
eukaryotic translation initiation factor 3 subunit G
chr1_-_43172504 13.13 ENST00000431635.6
EBNA1 binding protein 2
chr8_-_130016622 13.10 ENST00000518283.5
ENST00000519110.5
CYFIP related Rac1 interactor B
chr17_-_40417873 13.06 ENST00000423485.6
DNA topoisomerase II alpha
chr19_+_9827886 13.00 ENST00000358666.7
ENST00000590068.1
ENST00000593087.1
ENST00000586895.6
ubiquitin like 5
chr3_-_196942427 12.92 ENST00000411704.1
ENST00000452404.6
nuclear cap binding protein subunit 2
chr8_+_144078590 12.92 ENST00000525936.1
exosome component 4
chr17_+_63827406 12.75 ENST00000310144.11
ENST00000581842.5
ENST00000582130.5
ENST00000584320.5
ENST00000585123.5
ENST00000580864.5
proteasome 26S subunit, ATPase 5
chr6_-_170553216 12.64 ENST00000262193.7
proteasome 20S subunit beta 1
chr1_-_43172244 12.57 ENST00000236051.3
EBNA1 binding protein 2
chr12_+_107685759 12.49 ENST00000412830.8
ENST00000547995.5
PWP1 homolog, endonuclein
chr11_-_67437670 12.47 ENST00000326294.4
protein tyrosine phosphatase receptor type C associated protein
chr6_+_31666128 12.33 ENST00000375865.6
ENST00000375866.2
casein kinase 2 beta
chr17_-_21214122 12.32 ENST00000317635.6
transmembrane protein 11
chr17_+_36486629 12.31 ENST00000619730.4
zinc finger HIT-type containing 3
chr17_+_36486668 12.23 ENST00000617429.5
ENST00000620324.4
ENST00000616269.1
zinc finger HIT-type containing 3
chr15_-_64989435 12.22 ENST00000433215.6
ENST00000558415.5
ENST00000557795.5
SPG21 abhydrolase domain containing, maspardin
chr1_+_32222415 12.12 ENST00000678420.1
ENST00000678162.1
ENST00000678711.1
ENST00000678883.1
ENST00000677353.1
ENST00000355082.10
eukaryotic translation initiation factor 3 subunit I
chr9_+_124869126 12.08 ENST00000259477.6
actin related protein 2/3 complex subunit 5 like
chrX_+_101391000 12.08 ENST00000553110.8
ENST00000409338.5
ENST00000409170.3
ribosomal protein L36a
RPL36A-HNRNPH2 readthrough
chr5_+_96743536 12.05 ENST00000515663.5
calpastatin
chr14_+_96502358 12.01 ENST00000216277.13
ENST00000557320.5
ENST00000557471.5
poly(A) polymerase alpha
chr1_+_32222393 11.97 ENST00000676679.1
ENST00000678689.1
ENST00000373586.2
ENST00000679290.1
ENST00000677378.1
ENST00000678534.1
ENST00000678968.1
ENST00000678063.1
ENST00000678150.1
ENST00000677198.1
ENST00000677540.1
eukaryotic translation initiation factor 3 subunit I
chr19_+_7395112 11.93 ENST00000319670.14
Rho/Rac guanine nucleotide exchange factor 18
chr19_-_45691771 11.90 ENST00000588599.5
ENST00000585392.2
ENST00000590212.1
ENST00000587367.5
ENST00000391932.7
ENST00000342669.8
small nuclear ribonucleoprotein D2 polypeptide
chr12_+_131929259 11.85 ENST00000542167.2
ENST00000376649.8
ENST00000538037.5
ENST00000456665.6
pseudouridine synthase 1
chr20_+_62387086 11.82 ENST00000343986.9
ribosomal protein S21
chr19_-_58555085 11.82 ENST00000312547.7
charged multivesicular body protein 2A
chr19_+_48993525 11.76 ENST00000601968.5
ENST00000596837.5
RuvB like AAA ATPase 2
chrX_+_101390824 11.72 ENST00000427805.6
ENST00000614077.4
ribosomal protein L36a
chr19_+_19192229 11.67 ENST00000421262.7
ENST00000456252.7
ENST00000303088.9
ENST00000593273.5
regulatory factor X associated ankyrin containing protein
chr11_+_7987314 11.67 ENST00000531572.2
ENST00000651655.1
eukaryotic translation initiation factor 3 subunit F
chr13_+_40789548 11.65 ENST00000338625.9
solute carrier family 25 member 15
chr12_-_120469571 11.57 ENST00000550458.1
serine and arginine rich splicing factor 9
chr15_+_74782069 11.56 ENST00000220003.14
ENST00000439220.6
C-terminal Src kinase
chr19_-_16660104 11.55 ENST00000593459.5
ENST00000627144.2
ENST00000358726.6
ENST00000487416.7
ENST00000597711.5
novel protein
small integral membrane protein 7
chr1_-_19485468 11.50 ENST00000375142.5
capping actin protein of muscle Z-line subunit beta
chr15_+_41332862 11.49 ENST00000450592.6
ENST00000414849.6
ENST00000559596.6
ENST00000560747.5
ENST00000560177.5
nucleolar and spindle associated protein 1
chr11_-_18526885 11.49 ENST00000251968.4
ENST00000536719.5
tumor susceptibility 101
chr8_-_116766255 11.34 ENST00000276682.8
eukaryotic translation initiation factor 3 subunit H
chr12_+_131929194 11.20 ENST00000443358.6
pseudouridine synthase 1
chr19_+_48872412 11.20 ENST00000200453.6
protein phosphatase 1 regulatory subunit 15A
chr2_-_200963633 11.03 ENST00000234296.7
origin recognition complex subunit 2
chr11_+_60914139 10.94 ENST00000227525.8
transmembrane protein 109
chr19_+_54115726 10.78 ENST00000445811.5
ENST00000321030.9
ENST00000445124.5
ENST00000447810.5
pre-mRNA processing factor 31
chr8_-_123042244 10.74 ENST00000259512.9
ENST00000419562.6
derlin 1
chr17_-_31901658 10.74 ENST00000261708.9
UTP6 small subunit processome component
chr1_+_154220179 10.73 ENST00000343815.10
ubiquitin associated protein 2 like
chr6_-_144095556 10.66 ENST00000367569.4
splicing factor 3b subunit 5
chrX_+_101390976 10.61 ENST00000392994.7
ribosomal protein L36a
chr10_+_97319250 10.61 ENST00000371021.5
FRAT regulator of WNT signaling pathway 1
chr6_+_132814566 10.57 ENST00000230050.4
ribosomal protein S12
chr19_+_38619082 10.49 ENST00000614624.4
ENST00000593149.5
ENST00000538434.5
ENST00000588934.5
ENST00000248342.9
ENST00000545173.6
ENST00000591409.5
ENST00000592558.1
eukaryotic translation initiation factor 3 subunit K
chr8_+_144082586 10.47 ENST00000525087.5
ENST00000355091.9
ENST00000361036.10
ENST00000524418.5
glycosylphosphatidylinositol anchor attachment 1
chr14_+_22871732 10.43 ENST00000359591.9
LDL receptor related protein 10
chr12_+_50764054 10.34 ENST00000262053.8
activating transcription factor 1
chrX_+_101391202 10.33 ENST00000471855.1
ribosomal protein L36a
chr2_+_201116396 10.33 ENST00000395148.6
CASP8 and FADD like apoptosis regulator
chr6_+_31666056 10.27 ENST00000375882.7
ENST00000375880.6
casein kinase 2 beta
novel protein
chr6_-_127343518 10.12 ENST00000528402.5
ENST00000454591.6
ethylmalonyl-CoA decarboxylase 1
chr16_+_30064462 10.11 ENST00000412304.6
aldolase, fructose-bisphosphate A
chr6_-_127343590 10.09 ENST00000368291.6
ENST00000454859.8
ethylmalonyl-CoA decarboxylase 1
chr11_+_61792878 10.08 ENST00000305885.3
ENST00000535723.1
flap structure-specific endonuclease 1
chr12_-_8949628 10.03 ENST00000000412.8
ENST00000543845.1
ENST00000544245.1
ENST00000536844.5
mannose-6-phosphate receptor, cation dependent
chr17_+_74203582 9.85 ENST00000439590.6
ENST00000311111.11
ENST00000584577.5
ENST00000534490.5
ENST00000528433.2
ENST00000533498.1
ribosomal protein L38
chr19_+_11436044 9.83 ENST00000589838.5
protein kinase C substrate 80K-H
chr12_+_27710795 9.80 ENST00000081029.8
ENST00000538315.5
ENST00000542791.1
mitochondrial ribosomal protein S35
chr14_+_67360313 9.79 ENST00000256383.11
eukaryotic translation initiation factor 2 subunit alpha
chr1_+_159009886 9.67 ENST00000340979.10
ENST00000368131.8
ENST00000295809.12
ENST00000368132.7
interferon gamma inducible protein 16
chr6_+_146543824 9.64 ENST00000367495.4
RAB32, member RAS oncogene family
chr1_+_159010002 9.62 ENST00000359709.7
interferon gamma inducible protein 16
chr1_+_150321523 9.58 ENST00000324862.7
pre-mRNA processing factor 3
chr14_-_74713041 9.56 ENST00000356357.9
ENST00000555249.1
ENST00000681599.1
ENST00000556202.5
ENST00000681099.1
apoptosis resistant E3 ubiquitin protein ligase 1
chr18_-_47930630 9.47 ENST00000262160.11
SMAD family member 2
chr22_+_36913620 9.40 ENST00000403662.8
ENST00000262825.9
colony stimulating factor 2 receptor subunit beta
chr6_-_75243770 9.35 ENST00000472311.6
ENST00000460985.1
ENST00000377978.3
ENST00000684430.1
ENST00000509698.6
cytochrome c oxidase subunit 7A2
chr16_+_30064142 9.32 ENST00000562168.5
ENST00000569545.5
aldolase, fructose-bisphosphate A
chr5_+_115841878 9.28 ENST00000316788.12
adaptor related protein complex 3 subunit sigma 1
chr2_-_27409523 9.27 ENST00000344034.5
protein phosphatase, Mg2+/Mn2+ dependent 1G
chr9_+_33265013 9.26 ENST00000223500.9
charged multivesicular body protein 5
chr14_+_96502542 9.22 ENST00000556619.5
ENST00000392990.6
poly(A) polymerase alpha
chr15_+_80059651 9.15 ENST00000561012.5
ENST00000261749.11
ENST00000564367.5
ENST00000558494.5
zinc finger AN1-type containing 6
chr8_-_103415085 9.14 ENST00000297578.9
solute carrier family 25 member 32
chr17_-_81918134 9.12 ENST00000328666.11
sirtuin 7
chr10_+_7788162 9.10 ENST00000356708.12
ENST00000335698.4
ATP synthase F1 subunit gamma
chr10_-_5813387 9.09 ENST00000456041.5
ENST00000380181.7
ENST00000418688.5
ENST00000609712.1
ENST00000380191.9
GDP dissociation inhibitor 2
chr15_+_90388234 9.06 ENST00000268182.10
ENST00000560738.1
ENST00000560418.1
IQ motif containing GTPase activating protein 1
chr16_+_30064274 9.04 ENST00000563060.6
aldolase, fructose-bisphosphate A
chr10_+_22316445 8.90 ENST00000448361.5
COMM domain containing 3
chr13_-_31161927 8.90 ENST00000380405.7
heat shock protein family H (Hsp110) member 1
chr6_-_31652358 8.86 ENST00000456622.5
ENST00000435080.5
ENST00000375976.8
ENST00000441054.5
BAG cochaperone 6
chr7_+_44797114 8.77 ENST00000677022.1
peptidylprolyl isomerase A
chr3_-_196942500 8.76 ENST00000321256.10
ENST00000427641.2
nuclear cap binding protein subunit 2
chr5_+_31532277 8.57 ENST00000507818.6
ENST00000325366.14
chromosome 5 open reading frame 22
chr4_-_82373946 8.50 ENST00000352301.8
ENST00000509107.1
ENST00000353341.8
ENST00000313899.12
heterogeneous nuclear ribonucleoprotein D
chr22_-_41688799 8.44 ENST00000469028.2
ENST00000463675.6
ENST00000649479.1
ENST00000469522.1
small nuclear ribonucleoprotein 13
chr5_-_37371061 8.44 ENST00000513532.1
ENST00000231498.8
nucleoporin 155
chr7_+_151232464 8.38 ENST00000482173.5
ENST00000495645.5
ENST00000035307.6
chondroitin polymerizing factor 2
chr2_-_69387188 8.36 ENST00000674507.1
ENST00000357308.9
glutamine--fructose-6-phosphate transaminase 1
chr12_-_120469655 8.25 ENST00000229390.8
serine and arginine rich splicing factor 9
chr2_+_63842325 8.04 ENST00000445915.6
ENST00000475462.5
UDP-glucose pyrophosphorylase 2
chr1_+_2391775 8.02 ENST00000378513.7
ENST00000378518.5
ENST00000605895.6
ENST00000306256.13
ENST00000378512.5
retention in endoplasmic reticulum sorting receptor 1
chr9_+_98056694 8.01 ENST00000210444.6
N-acetylneuraminate synthase
chr14_-_67359769 7.92 ENST00000555431.5
ENST00000554236.5
ENST00000555474.5
ENST00000216442.12
ATPase H+ transporting V1 subunit D
chr4_+_41935423 7.87 ENST00000504986.6
transmembrane protein 33
chr6_-_127343329 7.83 ENST00000474289.6
ENST00000534442.5
ENST00000368289.6
ENST00000525745.5
ENST00000430841.6
ethylmalonyl-CoA decarboxylase 1

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
19.5 58.4 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
12.7 76.3 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
9.8 29.3 GO:0070902 mitochondrial tRNA pseudouridine synthesis(GO:0070902)
9.4 37.5 GO:0046833 snRNA export from nucleus(GO:0006408) positive regulation of RNA export from nucleus(GO:0046833)
9.1 36.3 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
8.6 25.7 GO:1903722 regulation of centriole elongation(GO:1903722)
8.4 42.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
7.9 31.7 GO:0071733 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
6.8 6.8 GO:1903094 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
6.2 86.6 GO:0015074 DNA integration(GO:0015074)
5.1 25.6 GO:0019348 dolichol metabolic process(GO:0019348)
5.1 40.6 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
5.0 30.2 GO:0030581 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
4.9 14.7 GO:1900224 positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224)
4.7 135.9 GO:0006465 signal peptide processing(GO:0006465)
4.4 22.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620) pronephric nephron development(GO:0039019)
4.4 39.2 GO:0006167 AMP biosynthetic process(GO:0006167)
3.9 11.7 GO:0015822 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
3.8 11.5 GO:1903774 ubiquitin-dependent endocytosis(GO:0070086) positive regulation of viral budding via host ESCRT complex(GO:1903774) regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
3.7 11.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
3.7 18.5 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
3.7 18.4 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
3.7 25.7 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
3.6 21.7 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
3.5 14.2 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
3.1 9.4 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043) interleukin-3-mediated signaling pathway(GO:0038156)
3.1 12.5 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
3.1 27.5 GO:0075525 viral translational termination-reinitiation(GO:0075525)
3.0 9.1 GO:0045897 positive regulation of transcription during mitosis(GO:0045897)
2.8 8.5 GO:1901355 response to rapamycin(GO:1901355)
2.8 22.6 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
2.8 41.8 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
2.8 22.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
2.8 13.8 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
2.5 7.6 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
2.5 15.0 GO:0019255 UDP-glucuronate biosynthetic process(GO:0006065) glucose 1-phosphate metabolic process(GO:0019255)
2.5 14.8 GO:0033152 immunoglobulin V(D)J recombination(GO:0033152)
2.5 12.3 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
2.4 9.8 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
2.4 26.9 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
2.4 11.8 GO:0031125 rRNA 3'-end processing(GO:0031125)
2.3 9.1 GO:0051182 coenzyme transport(GO:0051182)
2.3 6.8 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
2.2 6.7 GO:0034402 mRNA export from nucleus in response to heat stress(GO:0031990) recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
2.2 13.3 GO:1903899 positive regulation of PERK-mediated unfolded protein response(GO:1903899)
2.2 6.6 GO:1903719 positive regulation of endodeoxyribonuclease activity(GO:0032079) regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
2.2 6.5 GO:0002582 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
2.1 16.8 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
2.0 10.2 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
1.8 10.8 GO:0048254 snoRNA localization(GO:0048254)
1.7 22.1 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
1.7 5.0 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
1.6 9.6 GO:1903232 melanosome assembly(GO:1903232)
1.6 17.7 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
1.6 15.9 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
1.6 28.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
1.5 27.6 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
1.5 12.2 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
1.5 12.1 GO:1902661 positive regulation of glucose mediated signaling pathway(GO:1902661)
1.5 22.3 GO:0031053 primary miRNA processing(GO:0031053)
1.5 4.5 GO:0071336 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
1.5 4.4 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
1.5 5.8 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
1.5 13.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
1.4 13.0 GO:1904424 regulation of GTP binding(GO:1904424)
1.4 51.8 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
1.4 4.3 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
1.4 26.0 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
1.4 12.2 GO:0072553 terminal button organization(GO:0072553)
1.3 10.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
1.3 29.0 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
1.2 23.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
1.2 12.8 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
1.2 13.8 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
1.1 10.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
1.1 14.7 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
1.1 17.7 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
1.1 4.4 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
1.1 12.9 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
1.0 7.3 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
1.0 16.7 GO:0043248 proteasome assembly(GO:0043248)
1.0 14.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
1.0 17.2 GO:0070365 hepatocyte differentiation(GO:0070365)
1.0 6.1 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
1.0 7.8 GO:2000210 positive regulation of anoikis(GO:2000210)
1.0 8.8 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
1.0 5.7 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.9 36.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.9 10.0 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.9 7.0 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.9 7.7 GO:0071492 cellular response to UV-A(GO:0071492)
0.8 8.4 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.8 2.5 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.8 11.7 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.8 9.1 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.8 11.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.8 2.4 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.8 8.6 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.8 17.0 GO:0006491 N-glycan processing(GO:0006491)
0.8 6.8 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.8 96.6 GO:0045047 protein targeting to ER(GO:0045047)
0.8 24.8 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.7 8.7 GO:0006983 ER overload response(GO:0006983)
0.7 6.5 GO:0000710 meiotic mismatch repair(GO:0000710)
0.7 88.1 GO:0006413 translational initiation(GO:0006413)
0.7 58.8 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.7 10.3 GO:0032025 response to cobalt ion(GO:0032025)
0.7 45.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.7 3.4 GO:0043128 regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043126) positive regulation of 1-phosphatidylinositol 4-kinase activity(GO:0043128)
0.6 19.8 GO:0006376 mRNA splice site selection(GO:0006376)
0.6 12.1 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.6 7.0 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.6 9.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.6 8.0 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.6 1.2 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.6 18.9 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.6 21.2 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.6 4.6 GO:0070475 rRNA base methylation(GO:0070475)
0.6 4.5 GO:0009249 protein lipoylation(GO:0009249)
0.6 13.0 GO:0043101 purine-containing compound salvage(GO:0043101)
0.5 6.0 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.5 17.9 GO:0045841 negative regulation of mitotic metaphase/anaphase transition(GO:0045841) mitotic spindle checkpoint(GO:0071174)
0.5 7.6 GO:0009086 methionine biosynthetic process(GO:0009086)
0.5 8.0 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.5 6.8 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.5 5.2 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.5 6.2 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.5 8.7 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.5 9.3 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.5 5.6 GO:0045116 protein neddylation(GO:0045116)
0.5 0.9 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.5 9.9 GO:0006337 nucleosome disassembly(GO:0006337)
0.4 7.6 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.4 8.4 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.4 12.6 GO:0090383 phagosome acidification(GO:0090383)
0.4 7.1 GO:0006020 inositol metabolic process(GO:0006020)
0.4 1.7 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.4 8.8 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.4 4.0 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.4 4.8 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.4 28.9 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.4 32.7 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.4 1.9 GO:0030242 pexophagy(GO:0030242)
0.4 6.1 GO:0033197 response to vitamin E(GO:0033197)
0.4 1.1 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.4 13.6 GO:0045730 respiratory burst(GO:0045730)
0.3 1.7 GO:0061635 regulation of protein complex stability(GO:0061635)
0.3 1.0 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.3 2.4 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.3 2.0 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.3 5.7 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.3 7.7 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.3 1.0 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.3 5.2 GO:0006743 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.3 2.4 GO:0030091 protein repair(GO:0030091)
0.3 4.7 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.3 3.6 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.3 4.1 GO:0035456 response to interferon-beta(GO:0035456)
0.3 3.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.2 13.4 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.2 5.9 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.2 13.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.2 8.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.2 3.0 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.2 17.8 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.2 3.6 GO:0051014 actin filament severing(GO:0051014)
0.2 1.6 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.2 0.9 GO:0002881 negative regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002881)
0.2 10.1 GO:0006270 DNA replication initiation(GO:0006270)
0.2 5.8 GO:0047497 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.2 2.7 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.2 3.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 6.1 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.2 2.0 GO:1900103 positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.2 0.6 GO:0015785 UDP-galactose transport(GO:0015785) UDP-galactose transmembrane transport(GO:0072334)
0.2 1.2 GO:0009597 detection of virus(GO:0009597)
0.2 0.9 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.2 8.9 GO:0071377 cellular response to glucagon stimulus(GO:0071377)
0.2 10.9 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.2 10.7 GO:0051865 protein autoubiquitination(GO:0051865)
0.2 1.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 9.5 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.1 7.4 GO:0043647 inositol phosphate metabolic process(GO:0043647)
0.1 6.3 GO:0000271 polysaccharide biosynthetic process(GO:0000271)
0.1 4.4 GO:0021762 substantia nigra development(GO:0021762)
0.1 7.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 43.8 GO:0051056 regulation of small GTPase mediated signal transduction(GO:0051056)
0.1 1.8 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.1 5.1 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.1 24.8 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1 2.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 4.2 GO:0035722 interleukin-12-mediated signaling pathway(GO:0035722) cellular response to interleukin-12(GO:0071349)
0.1 0.7 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 1.5 GO:0007131 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.1 0.3 GO:0018032 peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
0.1 0.1 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.1 2.4 GO:0051028 mRNA transport(GO:0051028)
0.1 3.2 GO:0046686 response to cadmium ion(GO:0046686)
0.1 0.2 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 2.0 GO:0036297 interstrand cross-link repair(GO:0036297)
0.0 1.8 GO:0045668 negative regulation of osteoblast differentiation(GO:0045668)
0.0 2.6 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.3 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 1.6 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 6.6 GO:0006814 sodium ion transport(GO:0006814)
0.0 2.7 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.0 7.0 GO:0006913 nucleocytoplasmic transport(GO:0006913)
0.0 0.0 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.2 GO:0032460 negative regulation of protein oligomerization(GO:0032460) negative regulation of protein homooligomerization(GO:0032463)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
15.7 141.6 GO:0005787 signal peptidase complex(GO:0005787)
9.4 37.5 GO:0005846 nuclear cap binding complex(GO:0005846)
8.5 25.6 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
7.5 30.2 GO:0036502 Derlin-1-VIMP complex(GO:0036502)
7.4 29.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
7.1 70.8 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
6.0 42.2 GO:0034715 pICln-Sm protein complex(GO:0034715)
5.8 29.0 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
5.8 40.5 GO:0005956 protein kinase CK2 complex(GO:0005956)
4.6 13.8 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
4.5 13.4 GO:0097441 basilar dendrite(GO:0097441)
4.0 36.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
3.7 11.0 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
3.3 66.7 GO:0005885 Arp2/3 protein complex(GO:0005885)
3.2 31.7 GO:0097255 R2TP complex(GO:0097255)
3.1 15.4 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
3.0 14.8 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
2.9 14.7 GO:0032444 activin responsive factor complex(GO:0032444)
2.9 95.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
2.8 8.4 GO:0044611 nuclear pore inner ring(GO:0044611)
2.6 10.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
2.6 13.0 GO:1902560 GMP reductase complex(GO:1902560)
2.5 70.5 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
2.4 31.7 GO:0005686 U2 snRNP(GO:0005686)
2.4 7.3 GO:0005674 transcription factor TFIIF complex(GO:0005674)
2.3 6.8 GO:0033565 ESCRT-0 complex(GO:0033565)
2.2 28.9 GO:0000815 ESCRT III complex(GO:0000815)
2.2 26.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
2.1 10.7 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
2.1 25.7 GO:0071203 F-actin capping protein complex(GO:0008290) WASH complex(GO:0071203)
2.1 38.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
1.9 9.6 GO:0031905 early endosome lumen(GO:0031905)
1.9 26.9 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
1.9 17.2 GO:0000125 PCAF complex(GO:0000125)
1.9 22.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
1.7 5.0 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
1.5 12.3 GO:0061700 GATOR2 complex(GO:0061700)
1.5 5.8 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
1.4 17.9 GO:0017119 Golgi transport complex(GO:0017119)
1.3 6.6 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
1.3 6.5 GO:0097169 NLRP1 inflammasome complex(GO:0072558) AIM2 inflammasome complex(GO:0097169)
1.3 6.5 GO:0032301 MutSalpha complex(GO:0032301)
1.3 11.5 GO:0000813 ESCRT I complex(GO:0000813)
1.3 12.8 GO:0031595 nuclear proteasome complex(GO:0031595)
1.3 8.8 GO:0071439 clathrin complex(GO:0071439)
1.2 6.2 GO:0035061 interchromatin granule(GO:0035061)
1.2 26.9 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
1.2 4.7 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
1.2 46.6 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
1.1 13.8 GO:0030897 HOPS complex(GO:0030897)
1.0 3.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
1.0 13.3 GO:0000812 Swr1 complex(GO:0000812)
1.0 98.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.9 12.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.9 9.3 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.9 15.9 GO:0030686 90S preribosome(GO:0030686)
0.9 0.9 GO:0048500 signal recognition particle(GO:0048500)
0.9 13.0 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.8 2.5 GO:0070939 Dsl1p complex(GO:0070939)
0.8 17.0 GO:0005838 proteasome regulatory particle(GO:0005838)
0.8 25.6 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.8 4.0 GO:0032044 DSIF complex(GO:0032044)
0.7 45.2 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.7 9.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.7 18.5 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.7 2.7 GO:0071817 MMXD complex(GO:0071817)
0.7 11.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.6 22.0 GO:0071564 SWI/SNF complex(GO:0016514) npBAF complex(GO:0071564)
0.6 1.9 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.6 7.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.6 16.5 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.6 6.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.6 6.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.5 65.4 GO:0035578 azurophil granule lumen(GO:0035578)
0.5 30.3 GO:0031430 M band(GO:0031430)
0.5 2.0 GO:1990578 perinuclear endoplasmic reticulum membrane(GO:1990578)
0.5 5.0 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.5 26.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.5 29.7 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.5 29.4 GO:0045171 intercellular bridge(GO:0045171)
0.4 5.3 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.4 1.6 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.4 90.8 GO:0000793 condensed chromosome(GO:0000793)
0.4 14.2 GO:1902555 endoribonuclease complex(GO:1902555)
0.4 10.0 GO:0030904 retromer complex(GO:0030904)
0.4 9.8 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.4 7.3 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.3 10.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.3 6.8 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.3 1.0 GO:0031251 PAN complex(GO:0031251)
0.3 25.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.3 4.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.2 9.5 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.2 7.5 GO:0005840 ribosome(GO:0005840)
0.2 1.7 GO:0044754 autolysosome(GO:0044754)
0.2 40.8 GO:0005681 spliceosomal complex(GO:0005681)
0.2 2.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.2 1.5 GO:0070187 telosome(GO:0070187)
0.2 10.4 GO:0031519 PcG protein complex(GO:0031519)
0.2 3.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 3.6 GO:0042627 chylomicron(GO:0042627)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 12.1 GO:0005643 nuclear pore(GO:0005643)
0.1 4.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.1 8.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 13.8 GO:0101002 ficolin-1-rich granule(GO:0101002) ficolin-1-rich granule lumen(GO:1904813)
0.1 1.9 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 1.0 GO:0030008 TRAPP complex(GO:0030008)
0.1 1.7 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1 1.6 GO:0035580 specific granule lumen(GO:0035580)
0.1 3.4 GO:0005876 spindle microtubule(GO:0005876)
0.1 100.6 GO:0005739 mitochondrion(GO:0005739)
0.1 10.3 GO:0031301 integral component of organelle membrane(GO:0031301)
0.1 6.1 GO:0016605 PML body(GO:0016605)
0.0 18.9 GO:0005911 cell-cell junction(GO:0005911)
0.0 0.9 GO:0044298 neuronal cell body membrane(GO:0032809) cell body membrane(GO:0044298)
0.0 2.4 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 6.1 GO:0099572 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
9.8 29.3 GO:0004730 pseudouridylate synthase activity(GO:0004730)
9.3 28.0 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
8.5 25.6 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
7.8 62.1 GO:0070990 snRNP binding(GO:0070990)
7.0 42.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
6.1 36.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
5.9 64.7 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
5.4 21.4 GO:0042134 rRNA primary transcript binding(GO:0042134)
5.3 26.5 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
4.4 39.5 GO:0016842 amidine-lyase activity(GO:0016842)
4.4 13.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
4.1 29.0 GO:0030369 ICAM-3 receptor activity(GO:0030369)
4.0 15.9 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
3.9 11.7 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
3.7 15.0 GO:0003983 UTP:glucose-1-phosphate uridylyltransferase activity(GO:0003983) UTP-monosaccharide-1-phosphate uridylyltransferase activity(GO:0051748)
3.7 37.5 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
3.7 14.7 GO:0004360 glutamine-fructose-6-phosphate transaminase (isomerizing) activity(GO:0004360)
3.4 10.2 GO:0030622 U4atac snRNA binding(GO:0030622) box C/D snoRNA binding(GO:0034512)
3.2 9.6 GO:0035650 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
3.1 9.4 GO:0004912 interleukin-3 receptor activity(GO:0004912) interleukin-5 receptor activity(GO:0004914)
3.0 9.1 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
3.0 14.8 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
2.8 8.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
2.8 13.8 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
2.6 10.5 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
2.6 13.0 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
2.6 28.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
2.5 17.8 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
2.5 10.1 GO:0017108 5'-flap endonuclease activity(GO:0017108)
2.5 7.4 GO:0034416 phosphohistidine phosphatase activity(GO:0008969) bisphosphoglycerate phosphatase activity(GO:0034416) inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity(GO:0051717)
2.4 63.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
2.4 14.6 GO:0034511 U3 snoRNA binding(GO:0034511)
2.4 14.2 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
2.2 6.6 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
2.2 6.5 GO:0032090 Pyrin domain binding(GO:0032090)
2.1 10.6 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
2.1 16.8 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
2.1 35.2 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
2.0 138.3 GO:0003743 translation initiation factor activity(GO:0003743)
2.0 14.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
1.9 5.8 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
1.7 7.0 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
1.6 7.8 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
1.6 20.3 GO:0046790 virion binding(GO:0046790)
1.5 4.5 GO:0032427 GBD domain binding(GO:0032427)
1.4 7.1 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
1.4 12.8 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
1.4 14.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
1.3 6.5 GO:0032143 single thymine insertion binding(GO:0032143)
1.3 25.6 GO:0042609 CD4 receptor binding(GO:0042609)
1.2 12.1 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
1.1 14.7 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
1.1 7.6 GO:0008172 S-methyltransferase activity(GO:0008172)
1.1 5.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
1.0 7.3 GO:0015266 protein channel activity(GO:0015266)
1.0 6.0 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
1.0 2.9 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
1.0 26.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.9 14.0 GO:0019211 phosphatase activator activity(GO:0019211)
0.9 13.0 GO:0031386 protein tag(GO:0031386)
0.9 5.4 GO:0061665 SUMO ligase activity(GO:0061665)
0.9 26.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.9 13.6 GO:0016018 cyclosporin A binding(GO:0016018)
0.8 6.8 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.8 45.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.8 4.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.7 4.4 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.7 8.0 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.7 21.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.7 6.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.7 21.9 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.7 18.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.7 12.1 GO:0030957 Tat protein binding(GO:0030957)
0.7 141.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.6 11.0 GO:0003688 DNA replication origin binding(GO:0003688)
0.6 8.8 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.6 9.1 GO:0008517 folic acid transporter activity(GO:0008517)
0.6 18.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.6 3.6 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.6 5.7 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.6 8.5 GO:0003680 AT DNA binding(GO:0003680)
0.6 6.7 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.6 24.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.5 1.6 GO:0004577 N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity(GO:0004577)
0.5 22.1 GO:0043022 ribosome binding(GO:0043022)
0.5 97.9 GO:0047485 protein N-terminus binding(GO:0047485)
0.5 31.4 GO:0005080 protein kinase C binding(GO:0005080)
0.5 10.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.5 2.5 GO:0034235 GPI anchor binding(GO:0034235)
0.5 10.0 GO:0005537 mannose binding(GO:0005537)
0.5 4.4 GO:0089720 caspase binding(GO:0089720)
0.5 2.4 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.5 20.1 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.5 15.0 GO:0017091 AU-rich element binding(GO:0017091)
0.5 10.7 GO:0030515 snoRNA binding(GO:0030515)
0.5 22.6 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.5 0.9 GO:0030228 lipoprotein particle receptor activity(GO:0030228)
0.5 27.6 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.4 22.7 GO:0031491 nucleosome binding(GO:0031491)
0.4 7.5 GO:0043274 phospholipase binding(GO:0043274)
0.4 99.7 GO:0051015 actin filament binding(GO:0051015)
0.4 11.6 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.4 9.1 GO:0044548 GTPase inhibitor activity(GO:0005095) S100 protein binding(GO:0044548)
0.4 9.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.3 9.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.3 9.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.3 7.5 GO:0008135 translation factor activity, RNA binding(GO:0008135)
0.3 3.4 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.3 0.9 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.3 4.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.3 5.1 GO:0051400 BH domain binding(GO:0051400)
0.3 15.6 GO:0019212 phosphatase inhibitor activity(GO:0019212)
0.3 4.7 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.3 4.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.3 6.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.3 4.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.2 3.2 GO:0034185 apolipoprotein binding(GO:0034185)
0.2 1.2 GO:0000403 Y-form DNA binding(GO:0000403)
0.2 3.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.2 6.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.2 9.2 GO:0031593 polyubiquitin binding(GO:0031593)
0.2 2.0 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 0.7 GO:0032089 NACHT domain binding(GO:0032089)
0.2 0.9 GO:0016495 C-X3-C chemokine receptor activity(GO:0016495)
0.2 64.5 GO:0008236 serine-type peptidase activity(GO:0008236)
0.2 14.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.2 0.6 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 7.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 35.6 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.2 2.6 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.2 2.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.2 8.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.1 18.6 GO:0005262 calcium channel activity(GO:0005262)
0.1 3.2 GO:0030331 estrogen receptor binding(GO:0030331)
0.1 1.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 8.0 GO:0035064 methylated histone binding(GO:0035064)
0.1 1.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 22.5 GO:0001047 core promoter binding(GO:0001047)
0.1 1.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 29.4 GO:0005096 GTPase activator activity(GO:0005096)
0.1 1.6 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 7.9 GO:0008565 protein transporter activity(GO:0008565)
0.1 4.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 1.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 5.2 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 1.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 5.4 GO:0032947 protein complex scaffold(GO:0032947)
0.0 10.4 GO:0061659 ubiquitin-like protein ligase activity(GO:0061659)
0.0 7.8 GO:0022832 voltage-gated ion channel activity(GO:0005244) voltage-gated channel activity(GO:0022832)
0.0 1.9 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 3.8 GO:0015405 primary active transmembrane transporter activity(GO:0015399) P-P-bond-hydrolysis-driven transmembrane transporter activity(GO:0015405)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 55.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
1.1 54.3 PID MYC PATHWAY C-MYC pathway
1.1 65.8 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
1.0 26.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.7 11.2 PID BMP PATHWAY BMP receptor signaling
0.6 29.0 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.6 17.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.5 23.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.5 11.4 PID IL5 PATHWAY IL5-mediated signaling events
0.5 5.4 ST JAK STAT PATHWAY Jak-STAT Pathway
0.4 14.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.3 25.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.3 8.8 PID ARF 3PATHWAY Arf1 pathway
0.3 35.2 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.3 9.1 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.3 15.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.3 15.0 SIG BCR SIGNALING PATHWAY Members of the BCR signaling pathway
0.3 10.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.3 13.1 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 11.7 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.2 14.0 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.2 1.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 7.6 PID FOXO PATHWAY FoxO family signaling
0.1 7.5 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.1 4.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.1 9.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 3.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.1 8.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 6.8 PID TELOMERASE PATHWAY Regulation of Telomerase
0.1 6.8 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 3.9 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 2.0 PID BARD1 PATHWAY BARD1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
8.7 95.8 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
7.5 141.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
4.5 67.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
2.6 39.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
2.4 33.4 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
2.2 92.5 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
2.2 166.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
1.9 44.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
1.7 58.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
1.6 25.6 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
1.6 14.2 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
1.5 13.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
1.5 179.5 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
1.3 21.2 REACTOME PROCESSING OF CAPPED INTRONLESS PRE MRNA Genes involved in Processing of Capped Intronless Pre-mRNA
1.2 17.3 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
1.1 40.9 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
1.0 12.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.9 67.8 REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.8 19.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.8 11.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.7 21.7 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.7 49.4 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.7 21.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.7 11.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.6 15.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.6 15.0 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.6 14.4 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.5 48.7 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.5 20.0 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.5 13.0 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.5 10.8 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.5 17.2 REACTOME RNA POL II PRE TRANSCRIPTION EVENTS Genes involved in RNA Polymerase II Pre-transcription Events
0.5 11.6 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.5 14.8 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.5 12.6 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.5 32.2 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.4 6.1 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.4 15.0 REACTOME PROCESSING OF CAPPED INTRON CONTAINING PRE MRNA Genes involved in Processing of Capped Intron-Containing Pre-mRNA
0.4 27.5 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.4 32.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.4 9.4 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.4 8.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.4 6.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.4 11.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.3 10.3 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.3 4.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.3 8.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.3 7.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 5.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.2 1.7 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.2 5.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.2 1.5 REACTOME TELOMERE MAINTENANCE Genes involved in Telomere Maintenance
0.2 4.1 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.2 9.1 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.1 3.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 1.9 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 3.8 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 3.8 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.1 1.8 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 1.6 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 1.6 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.2 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 11.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 3.6 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 4.8 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.6 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules