Project
avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)
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Results for ETV7
Z-value: 0.94
Motif logo
Transcription factors associated with ETV7
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
ETV7
|
ENSG00000010030.14 | ETV7 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| ETV7 | hg38_v1_chr6_-_36387654_36387689 | -0.02 | 8.2e-01 | Click! |
Activity profile of ETV7 motif
Sorted Z-values of ETV7 motif
Network of associatons between targets according to the STRING database.
First level regulatory network of ETV7
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 7.6 | GO:1904274 | tricellular tight junction assembly(GO:1904274) |
| 1.1 | 12.6 | GO:0043152 | induction of bacterial agglutination(GO:0043152) |
| 1.1 | 10.1 | GO:0086042 | cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042) |
| 1.1 | 5.5 | GO:0071051 | polyadenylation-dependent snoRNA 3'-end processing(GO:0071051) |
| 1.0 | 3.1 | GO:1903006 | regulation of protein K63-linked deubiquitination(GO:1903004) positive regulation of protein K63-linked deubiquitination(GO:1903006) |
| 1.0 | 3.1 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
| 1.0 | 4.0 | GO:0046203 | spermidine catabolic process(GO:0046203) |
| 0.9 | 2.7 | GO:0071816 | tail-anchored membrane protein insertion into ER membrane(GO:0071816) |
| 0.8 | 2.5 | GO:1904440 | regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641) |
| 0.8 | 3.2 | GO:0010836 | negative regulation of protein ADP-ribosylation(GO:0010836) |
| 0.7 | 2.2 | GO:0009386 | translational attenuation(GO:0009386) |
| 0.7 | 3.6 | GO:0061107 | seminal vesicle development(GO:0061107) |
| 0.7 | 4.3 | GO:0075525 | viral translational termination-reinitiation(GO:0075525) |
| 0.7 | 2.0 | GO:0097460 | ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707) |
| 0.7 | 7.2 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
| 0.6 | 3.7 | GO:0000973 | posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) |
| 0.6 | 4.1 | GO:0006662 | glycerol ether metabolic process(GO:0006662) |
| 0.6 | 2.3 | GO:0014724 | regulation of twitch skeletal muscle contraction(GO:0014724) |
| 0.6 | 3.4 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.5 | 1.6 | GO:0001868 | regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869) |
| 0.5 | 1.6 | GO:0038155 | interleukin-23-mediated signaling pathway(GO:0038155) |
| 0.5 | 1.5 | GO:1903567 | negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568) |
| 0.5 | 2.3 | GO:0034398 | telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240) |
| 0.4 | 4.0 | GO:0002191 | cap-dependent translational initiation(GO:0002191) positive regulation of energy homeostasis(GO:2000507) |
| 0.4 | 1.3 | GO:1905053 | regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053) |
| 0.4 | 1.2 | GO:0031393 | negative regulation of prostaglandin biosynthetic process(GO:0031393) |
| 0.4 | 1.6 | GO:0055014 | atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014) |
| 0.4 | 3.8 | GO:0006116 | NADH oxidation(GO:0006116) |
| 0.4 | 2.6 | GO:0071279 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) cellular response to cobalt ion(GO:0071279) |
| 0.4 | 1.5 | GO:0035627 | ceramide transport(GO:0035627) |
| 0.4 | 6.8 | GO:0016180 | snRNA processing(GO:0016180) |
| 0.4 | 2.2 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
| 0.3 | 1.4 | GO:0046985 | positive regulation of hemoglobin biosynthetic process(GO:0046985) |
| 0.3 | 1.3 | GO:0050916 | sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917) |
| 0.3 | 1.0 | GO:0036245 | cellular response to menadione(GO:0036245) |
| 0.3 | 1.0 | GO:0051710 | regulation of cytolysis in other organism(GO:0051710) |
| 0.3 | 1.3 | GO:1905224 | clathrin-coated pit assembly(GO:1905224) |
| 0.3 | 1.9 | GO:1902261 | positive regulation of delayed rectifier potassium channel activity(GO:1902261) |
| 0.3 | 4.4 | GO:0021942 | radial glia guided migration of Purkinje cell(GO:0021942) |
| 0.3 | 0.9 | GO:0002184 | cytoplasmic translational termination(GO:0002184) |
| 0.3 | 5.8 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.3 | 2.9 | GO:0009048 | dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048) |
| 0.3 | 0.8 | GO:1901899 | positive regulation of relaxation of cardiac muscle(GO:1901899) |
| 0.3 | 1.6 | GO:0048619 | embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619) |
| 0.3 | 1.1 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
| 0.3 | 0.8 | GO:0015888 | thiamine transport(GO:0015888) thiamine transmembrane transport(GO:0071934) |
| 0.3 | 0.8 | GO:0000350 | generation of catalytic spliceosome for second transesterification step(GO:0000350) |
| 0.3 | 1.1 | GO:0019086 | late viral transcription(GO:0019086) |
| 0.3 | 1.0 | GO:1990928 | response to amino acid starvation(GO:1990928) |
| 0.3 | 2.0 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
| 0.3 | 1.8 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
| 0.3 | 2.3 | GO:0046654 | tetrahydrofolate biosynthetic process(GO:0046654) |
| 0.2 | 1.0 | GO:0086097 | phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097) |
| 0.2 | 0.7 | GO:0070476 | peptidyl-glutamine methylation(GO:0018364) RNA (guanine-N7)-methylation(GO:0036265) rRNA (guanine-N7)-methylation(GO:0070476) |
| 0.2 | 1.2 | GO:1900264 | regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264) |
| 0.2 | 2.7 | GO:1904424 | regulation of GTP binding(GO:1904424) |
| 0.2 | 0.7 | GO:0044565 | dendritic cell proliferation(GO:0044565) |
| 0.2 | 1.4 | GO:0015793 | glycerol transport(GO:0015793) |
| 0.2 | 0.9 | GO:0044240 | multicellular organism lipid catabolic process(GO:0044240) |
| 0.2 | 9.1 | GO:0071431 | tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431) |
| 0.2 | 5.5 | GO:0001580 | detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580) |
| 0.2 | 0.6 | GO:1903679 | regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690) |
| 0.2 | 0.6 | GO:1903939 | regulation of TORC2 signaling(GO:1903939) |
| 0.2 | 4.4 | GO:0031167 | rRNA methylation(GO:0031167) |
| 0.2 | 1.5 | GO:2000768 | positive regulation of nephron tubule epithelial cell differentiation(GO:2000768) |
| 0.2 | 1.0 | GO:0090131 | mesangial cell development(GO:0072143) glomerular mesangial cell development(GO:0072144) mesenchyme migration(GO:0090131) |
| 0.2 | 1.4 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
| 0.2 | 1.6 | GO:0000480 | endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480) |
| 0.2 | 0.6 | GO:0018406 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
| 0.2 | 0.6 | GO:1902948 | regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246) |
| 0.2 | 0.8 | GO:0045065 | cytotoxic T cell differentiation(GO:0045065) |
| 0.2 | 0.6 | GO:0019287 | isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287) |
| 0.2 | 1.3 | GO:0051533 | positive regulation of NFAT protein import into nucleus(GO:0051533) |
| 0.2 | 0.7 | GO:2000297 | negative regulation of synapse maturation(GO:2000297) |
| 0.2 | 1.7 | GO:0090240 | positive regulation of histone H4 acetylation(GO:0090240) |
| 0.2 | 1.2 | GO:0097396 | response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398) |
| 0.2 | 2.3 | GO:0007175 | negative regulation of epidermal growth factor-activated receptor activity(GO:0007175) |
| 0.2 | 0.8 | GO:0035694 | mitochondrial protein catabolic process(GO:0035694) |
| 0.2 | 1.1 | GO:0046618 | drug export(GO:0046618) |
| 0.2 | 0.8 | GO:0038163 | thrombopoietin-mediated signaling pathway(GO:0038163) |
| 0.2 | 1.1 | GO:0045079 | negative regulation of chemokine biosynthetic process(GO:0045079) |
| 0.2 | 0.5 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
| 0.2 | 2.1 | GO:0033015 | porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149) |
| 0.2 | 2.3 | GO:0010826 | negative regulation of centrosome duplication(GO:0010826) |
| 0.2 | 1.6 | GO:0097646 | calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647) |
| 0.2 | 1.1 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
| 0.2 | 1.4 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
| 0.2 | 0.9 | GO:0033504 | floor plate development(GO:0033504) |
| 0.2 | 2.4 | GO:0030150 | protein import into mitochondrial matrix(GO:0030150) |
| 0.2 | 2.0 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.1 | 6.2 | GO:0097284 | hepatocyte apoptotic process(GO:0097284) |
| 0.1 | 7.4 | GO:1901998 | toxin transport(GO:1901998) |
| 0.1 | 0.3 | GO:0015917 | aminophospholipid transport(GO:0015917) |
| 0.1 | 0.9 | GO:0060385 | olfactory nerve development(GO:0021553) axonogenesis involved in innervation(GO:0060385) |
| 0.1 | 3.3 | GO:0034315 | regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315) |
| 0.1 | 0.6 | GO:0036369 | transcription factor catabolic process(GO:0036369) |
| 0.1 | 3.8 | GO:0071157 | negative regulation of cell cycle arrest(GO:0071157) |
| 0.1 | 1.2 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
| 0.1 | 0.4 | GO:1902544 | regulation of DNA N-glycosylase activity(GO:1902544) |
| 0.1 | 0.8 | GO:0006651 | diacylglycerol biosynthetic process(GO:0006651) |
| 0.1 | 1.6 | GO:0000492 | box C/D snoRNP assembly(GO:0000492) |
| 0.1 | 1.3 | GO:0052697 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
| 0.1 | 0.6 | GO:0035106 | operant conditioning(GO:0035106) |
| 0.1 | 0.4 | GO:0019482 | beta-alanine metabolic process(GO:0019482) |
| 0.1 | 1.5 | GO:0032471 | negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471) |
| 0.1 | 0.7 | GO:0071105 | response to interleukin-11(GO:0071105) |
| 0.1 | 1.2 | GO:2000346 | negative regulation of hepatocyte proliferation(GO:2000346) |
| 0.1 | 3.2 | GO:0007141 | male meiosis I(GO:0007141) |
| 0.1 | 1.1 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.1 | 1.0 | GO:0007135 | meiosis II(GO:0007135) |
| 0.1 | 0.3 | GO:0006106 | fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533) |
| 0.1 | 1.0 | GO:0008612 | peptidyl-lysine modification to peptidyl-hypusine(GO:0008612) |
| 0.1 | 3.2 | GO:0031063 | regulation of histone deacetylation(GO:0031063) |
| 0.1 | 2.1 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663) |
| 0.1 | 0.9 | GO:0042256 | mature ribosome assembly(GO:0042256) |
| 0.1 | 1.0 | GO:2000286 | receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
| 0.1 | 0.6 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
| 0.1 | 0.9 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.1 | 0.5 | GO:1901978 | positive regulation of cell cycle checkpoint(GO:1901978) |
| 0.1 | 0.5 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
| 0.1 | 3.3 | GO:0071526 | semaphorin-plexin signaling pathway(GO:0071526) |
| 0.1 | 0.7 | GO:0007621 | negative regulation of female receptivity(GO:0007621) female courtship behavior(GO:0008050) |
| 0.1 | 0.5 | GO:0051415 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 0.1 | 0.3 | GO:0042137 | sequestering of neurotransmitter(GO:0042137) |
| 0.1 | 1.3 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
| 0.1 | 4.8 | GO:0006730 | one-carbon metabolic process(GO:0006730) |
| 0.1 | 7.8 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.1 | 1.2 | GO:0032988 | ribonucleoprotein complex disassembly(GO:0032988) |
| 0.1 | 0.5 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
| 0.1 | 0.7 | GO:0006203 | dGTP catabolic process(GO:0006203) |
| 0.1 | 0.4 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
| 0.1 | 0.3 | GO:1903487 | regulation of lactation(GO:1903487) |
| 0.1 | 1.0 | GO:0014877 | response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
| 0.1 | 0.9 | GO:0070129 | regulation of mitochondrial translation(GO:0070129) |
| 0.1 | 1.9 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
| 0.1 | 0.8 | GO:1903799 | negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799) |
| 0.1 | 1.5 | GO:0016254 | preassembly of GPI anchor in ER membrane(GO:0016254) |
| 0.1 | 0.9 | GO:2000288 | positive regulation of myoblast proliferation(GO:2000288) |
| 0.1 | 0.4 | GO:0021648 | thorax and anterior abdomen determination(GO:0007356) vestibulocochlear nerve morphogenesis(GO:0021648) vestibulocochlear nerve formation(GO:0021650) |
| 0.1 | 0.1 | GO:1904569 | regulation of selenocysteine incorporation(GO:1904569) |
| 0.1 | 0.2 | GO:0046549 | retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549) |
| 0.1 | 0.8 | GO:0060124 | positive regulation of growth hormone secretion(GO:0060124) |
| 0.1 | 1.3 | GO:0043982 | histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982) |
| 0.1 | 1.3 | GO:0015671 | oxygen transport(GO:0015671) |
| 0.1 | 0.5 | GO:0006102 | isocitrate metabolic process(GO:0006102) |
| 0.1 | 0.2 | GO:0002025 | vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025) positive regulation of the force of heart contraction by chemical signal(GO:0003099) |
| 0.1 | 0.3 | GO:0042713 | sperm ejaculation(GO:0042713) |
| 0.1 | 0.5 | GO:0007256 | activation of JNKK activity(GO:0007256) |
| 0.1 | 0.2 | GO:0019075 | virus maturation(GO:0019075) |
| 0.1 | 1.2 | GO:0090051 | negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) |
| 0.1 | 0.9 | GO:0070544 | histone H3-K36 demethylation(GO:0070544) |
| 0.1 | 1.2 | GO:0043923 | positive regulation by host of viral transcription(GO:0043923) |
| 0.1 | 0.8 | GO:0018206 | peptidyl-methionine modification(GO:0018206) |
| 0.1 | 0.9 | GO:0090110 | cargo loading into COPII-coated vesicle(GO:0090110) |
| 0.1 | 1.2 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
| 0.1 | 0.7 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.1 | 4.0 | GO:0090502 | RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502) |
| 0.1 | 0.5 | GO:0097039 | protein linear polyubiquitination(GO:0097039) |
| 0.1 | 0.2 | GO:1990022 | RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022) |
| 0.1 | 2.0 | GO:1901799 | negative regulation of proteasomal protein catabolic process(GO:1901799) |
| 0.1 | 1.3 | GO:0008334 | histone mRNA metabolic process(GO:0008334) |
| 0.1 | 1.1 | GO:0070932 | histone H3 deacetylation(GO:0070932) |
| 0.1 | 0.9 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
| 0.1 | 1.5 | GO:0007171 | activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) |
| 0.1 | 0.6 | GO:0043249 | erythrocyte maturation(GO:0043249) |
| 0.1 | 0.4 | GO:1901668 | regulation of superoxide dismutase activity(GO:1901668) |
| 0.0 | 0.5 | GO:0031665 | negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665) |
| 0.0 | 0.5 | GO:1902455 | negative regulation of stem cell population maintenance(GO:1902455) |
| 0.0 | 0.3 | GO:0042483 | negative regulation of odontogenesis(GO:0042483) |
| 0.0 | 0.8 | GO:0060766 | negative regulation of androgen receptor signaling pathway(GO:0060766) |
| 0.0 | 12.2 | GO:0007565 | female pregnancy(GO:0007565) |
| 0.0 | 0.3 | GO:0017183 | peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) |
| 0.0 | 0.6 | GO:0072520 | seminiferous tubule development(GO:0072520) |
| 0.0 | 0.5 | GO:0003413 | chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413) |
| 0.0 | 0.7 | GO:0045475 | locomotor rhythm(GO:0045475) retinal rod cell development(GO:0046548) |
| 0.0 | 0.2 | GO:0033277 | abortive mitotic cell cycle(GO:0033277) |
| 0.0 | 0.8 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.0 | 0.3 | GO:0048742 | regulation of skeletal muscle fiber development(GO:0048742) |
| 0.0 | 4.6 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
| 0.0 | 0.2 | GO:0015891 | iron chelate transport(GO:0015688) siderophore transport(GO:0015891) sensory perception of sour taste(GO:0050915) |
| 0.0 | 1.5 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
| 0.0 | 2.8 | GO:0045540 | regulation of cholesterol biosynthetic process(GO:0045540) |
| 0.0 | 1.2 | GO:0051567 | histone H3-K9 methylation(GO:0051567) |
| 0.0 | 0.1 | GO:0006842 | tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746) |
| 0.0 | 0.6 | GO:0032042 | mitochondrial DNA metabolic process(GO:0032042) |
| 0.0 | 2.0 | GO:0006940 | regulation of smooth muscle contraction(GO:0006940) |
| 0.0 | 0.1 | GO:0048213 | Golgi vesicle prefusion complex stabilization(GO:0048213) |
| 0.0 | 3.1 | GO:0008033 | tRNA processing(GO:0008033) |
| 0.0 | 0.2 | GO:0014916 | regulation of lung blood pressure(GO:0014916) negative regulation of lung blood pressure(GO:0061767) |
| 0.0 | 0.7 | GO:0031297 | replication fork processing(GO:0031297) |
| 0.0 | 0.5 | GO:0002158 | osteoclast proliferation(GO:0002158) |
| 0.0 | 1.6 | GO:0045839 | negative regulation of mitotic nuclear division(GO:0045839) |
| 0.0 | 0.8 | GO:0050995 | negative regulation of lipid catabolic process(GO:0050995) |
| 0.0 | 0.5 | GO:0060009 | Sertoli cell development(GO:0060009) |
| 0.0 | 4.3 | GO:2000134 | negative regulation of G1/S transition of mitotic cell cycle(GO:2000134) |
| 0.0 | 0.4 | GO:1903800 | regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
| 0.0 | 0.4 | GO:0051014 | actin filament severing(GO:0051014) |
| 0.0 | 0.2 | GO:1990440 | positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440) |
| 0.0 | 1.4 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.0 | 0.2 | GO:0010936 | negative regulation of macrophage cytokine production(GO:0010936) |
| 0.0 | 1.6 | GO:0016574 | histone ubiquitination(GO:0016574) |
| 0.0 | 1.0 | GO:0090503 | RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503) |
| 0.0 | 0.4 | GO:0007258 | JUN phosphorylation(GO:0007258) |
| 0.0 | 1.1 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
| 0.0 | 0.4 | GO:0050942 | positive regulation of pigment cell differentiation(GO:0050942) |
| 0.0 | 0.7 | GO:0007158 | neuron cell-cell adhesion(GO:0007158) |
| 0.0 | 0.8 | GO:0030490 | maturation of SSU-rRNA(GO:0030490) |
| 0.0 | 0.5 | GO:0006853 | carnitine shuttle(GO:0006853) |
| 0.0 | 0.8 | GO:1902230 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230) |
| 0.0 | 1.0 | GO:0006099 | tricarboxylic acid cycle(GO:0006099) |
| 0.0 | 0.3 | GO:0090129 | positive regulation of synapse maturation(GO:0090129) |
| 0.0 | 0.8 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.0 | 1.2 | GO:0030330 | DNA damage response, signal transduction by p53 class mediator(GO:0030330) |
| 0.0 | 0.8 | GO:0007339 | binding of sperm to zona pellucida(GO:0007339) |
| 0.0 | 0.9 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.0 | 1.3 | GO:0043001 | Golgi to plasma membrane protein transport(GO:0043001) |
| 0.0 | 0.8 | GO:0014059 | dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059) |
| 0.0 | 0.7 | GO:0006471 | protein ADP-ribosylation(GO:0006471) |
| 0.0 | 0.2 | GO:0001887 | selenium compound metabolic process(GO:0001887) |
| 0.0 | 2.0 | GO:0035249 | synaptic transmission, glutamatergic(GO:0035249) |
| 0.0 | 3.0 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.0 | 0.7 | GO:0070498 | interleukin-1-mediated signaling pathway(GO:0070498) |
| 0.0 | 1.4 | GO:0002548 | monocyte chemotaxis(GO:0002548) |
| 0.0 | 0.6 | GO:0061049 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.0 | 0.1 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 0.0 | 0.2 | GO:0006265 | DNA topological change(GO:0006265) |
| 0.0 | 0.7 | GO:0008593 | regulation of Notch signaling pathway(GO:0008593) |
| 0.0 | 0.2 | GO:0031069 | hair follicle morphogenesis(GO:0031069) |
| 0.0 | 0.2 | GO:1902414 | protein localization to cell junction(GO:1902414) |
| 0.0 | 0.2 | GO:1903817 | negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817) |
| 0.0 | 0.3 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 0.0 | 0.9 | GO:0043616 | keratinocyte proliferation(GO:0043616) |
| 0.0 | 0.5 | GO:0032958 | inositol phosphate biosynthetic process(GO:0032958) |
| 0.0 | 6.6 | GO:0010038 | response to metal ion(GO:0010038) |
| 0.0 | 1.0 | GO:0003009 | skeletal muscle contraction(GO:0003009) |
| 0.0 | 2.3 | GO:0007286 | spermatid development(GO:0007286) |
| 0.0 | 0.1 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.0 | 1.2 | GO:0071300 | cellular response to retinoic acid(GO:0071300) |
| 0.0 | 0.6 | GO:0048268 | clathrin coat assembly(GO:0048268) |
| 0.0 | 0.7 | GO:0045773 | positive regulation of axon extension(GO:0045773) |
| 0.0 | 0.5 | GO:0042572 | retinol metabolic process(GO:0042572) |
| 0.0 | 1.2 | GO:0090307 | mitotic spindle assembly(GO:0090307) |
| 0.0 | 1.7 | GO:0030183 | B cell differentiation(GO:0030183) |
| 0.0 | 0.7 | GO:0051298 | centrosome duplication(GO:0051298) |
| 0.0 | 1.0 | GO:0042795 | snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.0 | 0.4 | GO:0006308 | DNA catabolic process(GO:0006308) |
| 0.0 | 0.5 | GO:0019228 | neuronal action potential(GO:0019228) |
| 0.0 | 0.1 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.0 | 1.4 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
| 0.0 | 0.8 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
| 0.0 | 0.1 | GO:0017062 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) |
| 0.0 | 0.9 | GO:0032091 | negative regulation of protein binding(GO:0032091) |
| 0.0 | 0.2 | GO:0060037 | pharyngeal system development(GO:0060037) |
| 0.0 | 1.8 | GO:0007608 | sensory perception of smell(GO:0007608) |
| 0.0 | 4.2 | GO:0001558 | regulation of cell growth(GO:0001558) |
| 0.0 | 1.3 | GO:0006687 | glycosphingolipid metabolic process(GO:0006687) |
| 0.0 | 0.2 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) |
| 0.0 | 0.0 | GO:0045645 | regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) |
| 0.0 | 1.2 | GO:0007062 | sister chromatid cohesion(GO:0007062) |
| 0.0 | 1.1 | GO:1903955 | positive regulation of protein targeting to mitochondrion(GO:1903955) |
| 0.0 | 0.1 | GO:0015868 | purine nucleotide transport(GO:0015865) purine ribonucleotide transport(GO:0015868) |
| 0.0 | 0.3 | GO:0019370 | leukotriene biosynthetic process(GO:0019370) |
| 0.0 | 0.4 | GO:0000079 | regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0000079) |
| 0.0 | 2.4 | GO:0018105 | peptidyl-serine phosphorylation(GO:0018105) |
| 0.0 | 0.0 | GO:0043553 | negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) |
| 0.0 | 0.6 | GO:0021510 | spinal cord development(GO:0021510) |
| 0.0 | 0.3 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 6.6 | GO:1990876 | cytoplasmic side of nuclear pore(GO:1990876) |
| 1.2 | 3.6 | GO:0097182 | protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183) |
| 1.0 | 3.0 | GO:0000799 | nuclear condensin complex(GO:0000799) |
| 0.9 | 7.6 | GO:0061689 | tricellular tight junction(GO:0061689) |
| 0.9 | 2.7 | GO:0071818 | BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379) |
| 0.7 | 2.7 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
| 0.6 | 12.3 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.5 | 1.6 | GO:0072536 | interleukin-23 receptor complex(GO:0072536) |
| 0.5 | 2.6 | GO:0000796 | condensin complex(GO:0000796) |
| 0.5 | 3.1 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
| 0.5 | 2.1 | GO:0097123 | cyclin A1-CDK2 complex(GO:0097123) |
| 0.4 | 5.5 | GO:0000176 | nuclear exosome (RNase complex)(GO:0000176) |
| 0.4 | 2.5 | GO:1990357 | terminal web(GO:1990357) |
| 0.4 | 3.0 | GO:0031931 | TORC1 complex(GO:0031931) |
| 0.3 | 1.0 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
| 0.3 | 4.5 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.3 | 2.7 | GO:0000322 | storage vacuole(GO:0000322) |
| 0.3 | 1.3 | GO:0071159 | NF-kappaB complex(GO:0071159) |
| 0.3 | 1.6 | GO:0001651 | dense fibrillar component(GO:0001651) |
| 0.3 | 3.4 | GO:0032039 | integrator complex(GO:0032039) |
| 0.3 | 0.9 | GO:0018444 | translation release factor complex(GO:0018444) |
| 0.3 | 5.6 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.3 | 1.4 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 0.3 | 2.0 | GO:0045252 | oxoglutarate dehydrogenase complex(GO:0045252) |
| 0.3 | 1.9 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
| 0.3 | 4.2 | GO:0035102 | PRC1 complex(GO:0035102) |
| 0.3 | 1.0 | GO:0005850 | eukaryotic translation initiation factor 2 complex(GO:0005850) |
| 0.2 | 1.2 | GO:0071008 | U2-type post-mRNA release spliceosomal complex(GO:0071008) |
| 0.2 | 2.6 | GO:0043203 | axon hillock(GO:0043203) |
| 0.2 | 0.7 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
| 0.2 | 6.2 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.2 | 4.0 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
| 0.2 | 3.3 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.2 | 0.6 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.2 | 1.2 | GO:0031390 | Ctf18 RFC-like complex(GO:0031390) |
| 0.2 | 1.6 | GO:1903439 | calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440) |
| 0.2 | 1.7 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
| 0.2 | 1.3 | GO:0005683 | U7 snRNP(GO:0005683) |
| 0.2 | 7.4 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.2 | 0.7 | GO:0000801 | central element(GO:0000801) |
| 0.2 | 0.5 | GO:0044609 | DBIRD complex(GO:0044609) |
| 0.2 | 1.4 | GO:0072487 | MSL complex(GO:0072487) |
| 0.2 | 0.8 | GO:0071012 | catalytic step 1 spliceosome(GO:0071012) |
| 0.2 | 0.8 | GO:0000408 | EKC/KEOPS complex(GO:0000408) |
| 0.2 | 2.3 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.2 | 0.5 | GO:0002081 | inner acrosomal membrane(GO:0002079) outer acrosomal membrane(GO:0002081) |
| 0.2 | 1.4 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
| 0.2 | 2.7 | GO:0036038 | MKS complex(GO:0036038) |
| 0.2 | 2.0 | GO:0042555 | MCM complex(GO:0042555) |
| 0.1 | 1.8 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.1 | 0.8 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.1 | 1.4 | GO:0034709 | methylosome(GO:0034709) |
| 0.1 | 0.4 | GO:0000939 | condensed chromosome inner kinetochore(GO:0000939) |
| 0.1 | 0.6 | GO:0045293 | MIS complex(GO:0036396) mRNA editing complex(GO:0045293) |
| 0.1 | 1.6 | GO:0034993 | microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993) |
| 0.1 | 2.4 | GO:0000812 | Swr1 complex(GO:0000812) |
| 0.1 | 0.5 | GO:0008275 | gamma-tubulin small complex(GO:0008275) |
| 0.1 | 1.6 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.1 | 1.8 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.1 | 0.5 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
| 0.1 | 2.6 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
| 0.1 | 1.0 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.1 | 9.5 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 1.0 | GO:0005638 | lamin filament(GO:0005638) |
| 0.1 | 1.1 | GO:0001673 | male germ cell nucleus(GO:0001673) |
| 0.1 | 1.3 | GO:0005833 | hemoglobin complex(GO:0005833) |
| 0.1 | 2.8 | GO:0005640 | nuclear outer membrane(GO:0005640) |
| 0.1 | 0.8 | GO:0097550 | transcriptional preinitiation complex(GO:0097550) |
| 0.1 | 4.1 | GO:0031941 | filamentous actin(GO:0031941) |
| 0.1 | 0.8 | GO:0033018 | sarcoplasmic reticulum lumen(GO:0033018) |
| 0.1 | 2.3 | GO:0032982 | myosin filament(GO:0032982) |
| 0.1 | 0.5 | GO:0071797 | LUBAC complex(GO:0071797) |
| 0.1 | 0.4 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.1 | 0.4 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.1 | 0.8 | GO:0044613 | nuclear pore central transport channel(GO:0044613) |
| 0.1 | 1.4 | GO:0001527 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.1 | 0.4 | GO:0033655 | host cell cytoplasm(GO:0030430) host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648) host cell cytoplasm part(GO:0033655) |
| 0.1 | 0.7 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.1 | 1.6 | GO:0005719 | nuclear euchromatin(GO:0005719) |
| 0.1 | 5.6 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.1 | 2.1 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.1 | 2.6 | GO:0005669 | transcription factor TFIID complex(GO:0005669) |
| 0.1 | 0.3 | GO:0060199 | clathrin-sculpted glutamate transport vesicle(GO:0060199) clathrin-sculpted glutamate transport vesicle membrane(GO:0060203) |
| 0.1 | 1.0 | GO:0035327 | transcriptionally active chromatin(GO:0035327) |
| 0.1 | 1.4 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.1 | 1.5 | GO:0031528 | microvillus membrane(GO:0031528) |
| 0.1 | 4.5 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.1 | 1.9 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.1 | 0.4 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 0.0 | 4.7 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.8 | GO:0070069 | cytochrome complex(GO:0070069) |
| 0.0 | 0.1 | GO:0005953 | CAAX-protein geranylgeranyltransferase complex(GO:0005953) |
| 0.0 | 3.4 | GO:0044215 | other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) |
| 0.0 | 1.8 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 0.6 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 0.9 | GO:0005861 | troponin complex(GO:0005861) |
| 0.0 | 0.3 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.0 | 0.3 | GO:0097038 | perinuclear endoplasmic reticulum(GO:0097038) |
| 0.0 | 0.7 | GO:0030127 | COPII vesicle coat(GO:0030127) |
| 0.0 | 2.7 | GO:0043195 | terminal bouton(GO:0043195) |
| 0.0 | 0.5 | GO:0005689 | U12-type spliceosomal complex(GO:0005689) |
| 0.0 | 1.0 | GO:0042101 | T cell receptor complex(GO:0042101) |
| 0.0 | 2.1 | GO:0005747 | mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271) |
| 0.0 | 0.4 | GO:0031462 | Cul2-RING ubiquitin ligase complex(GO:0031462) |
| 0.0 | 2.0 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.2 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
| 0.0 | 0.4 | GO:0001931 | uropod(GO:0001931) cell trailing edge(GO:0031254) |
| 0.0 | 1.6 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 0.8 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.0 | 2.5 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 2.5 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 0.2 | GO:0005851 | eukaryotic translation initiation factor 2B complex(GO:0005851) |
| 0.0 | 2.0 | GO:0031672 | A band(GO:0031672) |
| 0.0 | 4.3 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.0 | 0.4 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.0 | 0.5 | GO:0031588 | nucleotide-activated protein kinase complex(GO:0031588) |
| 0.0 | 0.2 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
| 0.0 | 0.3 | GO:0030008 | TRAPP complex(GO:0030008) |
| 0.0 | 0.8 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.0 | 1.0 | GO:0045095 | keratin filament(GO:0045095) |
| 0.0 | 1.6 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 0.4 | GO:0034045 | pre-autophagosomal structure membrane(GO:0034045) |
| 0.0 | 0.1 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.0 | 1.2 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 0.1 | GO:0000120 | RNA polymerase I transcription factor complex(GO:0000120) |
| 0.0 | 1.4 | GO:0035580 | specific granule lumen(GO:0035580) |
| 0.0 | 0.5 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
| 0.0 | 2.5 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 1.0 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 6.2 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 2.1 | GO:0030018 | Z disc(GO:0030018) |
| 0.0 | 0.9 | GO:0001917 | photoreceptor inner segment(GO:0001917) |
| 0.0 | 0.6 | GO:0005876 | spindle microtubule(GO:0005876) |
| 0.0 | 0.3 | GO:0042599 | lamellar body(GO:0042599) |
| 0.0 | 0.5 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 2.6 | GO:0005840 | ribosome(GO:0005840) |
| 0.0 | 0.2 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.0 | 1.4 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.0 | 5.1 | GO:0000785 | chromatin(GO:0000785) |
| 0.0 | 5.0 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.0 | 0.4 | GO:0005839 | proteasome core complex(GO:0005839) |
| 0.0 | 1.3 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.0 | 1.0 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 4.1 | 12.3 | GO:0035375 | zymogen binding(GO:0035375) |
| 1.3 | 3.8 | GO:0004611 | phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613) |
| 1.1 | 4.3 | GO:0051734 | ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734) |
| 1.1 | 4.3 | GO:0019828 | aspartic-type endopeptidase inhibitor activity(GO:0019828) |
| 1.0 | 3.1 | GO:0098808 | mRNA cap binding(GO:0098808) |
| 0.9 | 2.8 | GO:0050613 | delta14-sterol reductase activity(GO:0050613) |
| 0.8 | 4.1 | GO:0033743 | peptide-methionine (S)-S-oxide reductase activity(GO:0008113) peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
| 0.8 | 4.0 | GO:0004522 | ribonuclease A activity(GO:0004522) |
| 0.8 | 6.2 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 0.8 | 4.5 | GO:0000179 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) |
| 0.7 | 6.8 | GO:0004064 | arylesterase activity(GO:0004064) |
| 0.7 | 4.0 | GO:0086080 | protein binding involved in heterotypic cell-cell adhesion(GO:0086080) |
| 0.6 | 1.8 | GO:0004998 | transferrin receptor activity(GO:0004998) |
| 0.6 | 2.3 | GO:0004146 | dihydrofolate reductase activity(GO:0004146) |
| 0.5 | 1.6 | GO:0042019 | interleukin-23 binding(GO:0042019) interleukin-23 receptor activity(GO:0042020) |
| 0.5 | 1.6 | GO:0034512 | box C/D snoRNA binding(GO:0034512) |
| 0.5 | 3.7 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.5 | 2.1 | GO:0004074 | biliverdin reductase activity(GO:0004074) |
| 0.5 | 3.3 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.5 | 1.4 | GO:0052810 | 1-phosphatidylinositol-5-kinase activity(GO:0052810) |
| 0.4 | 6.6 | GO:0005049 | nuclear export signal receptor activity(GO:0005049) |
| 0.4 | 3.6 | GO:0032190 | acrosin binding(GO:0032190) |
| 0.4 | 1.2 | GO:0005136 | interleukin-4 receptor binding(GO:0005136) |
| 0.4 | 4.4 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.4 | 1.2 | GO:0060001 | minus-end directed microfilament motor activity(GO:0060001) |
| 0.4 | 2.0 | GO:0004591 | oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591) |
| 0.4 | 1.5 | GO:0097001 | ceramide binding(GO:0097001) |
| 0.4 | 1.4 | GO:0015254 | glycerol channel activity(GO:0015254) |
| 0.3 | 3.7 | GO:0001135 | transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135) |
| 0.3 | 1.3 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
| 0.3 | 1.0 | GO:0001596 | angiotensin type I receptor activity(GO:0001596) |
| 0.3 | 1.3 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 0.3 | 6.1 | GO:0070273 | phosphatidylinositol-4-phosphate binding(GO:0070273) |
| 0.3 | 1.1 | GO:0015307 | drug:proton antiporter activity(GO:0015307) |
| 0.3 | 0.8 | GO:0003917 | DNA topoisomerase type I activity(GO:0003917) |
| 0.3 | 2.5 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.3 | 4.4 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.3 | 1.1 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
| 0.3 | 0.8 | GO:0015234 | thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) |
| 0.3 | 1.1 | GO:0015526 | hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513) |
| 0.2 | 4.2 | GO:0008320 | protein transmembrane transporter activity(GO:0008320) |
| 0.2 | 1.2 | GO:0047374 | methylumbelliferyl-acetate deacetylase activity(GO:0047374) |
| 0.2 | 4.6 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.2 | 0.7 | GO:0035529 | NADH pyrophosphatase activity(GO:0035529) |
| 0.2 | 6.8 | GO:0098641 | cadherin binding involved in cell-cell adhesion(GO:0098641) |
| 0.2 | 1.4 | GO:0044020 | histone methyltransferase activity (H4-R3 specific)(GO:0044020) |
| 0.2 | 3.1 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.2 | 0.6 | GO:0016422 | mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422) |
| 0.2 | 0.6 | GO:0016497 | substance K receptor activity(GO:0016497) |
| 0.2 | 1.4 | GO:0030023 | extracellular matrix constituent conferring elasticity(GO:0030023) |
| 0.2 | 0.6 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.2 | 1.6 | GO:0097643 | amylin receptor activity(GO:0097643) |
| 0.2 | 1.3 | GO:0030492 | hemoglobin binding(GO:0030492) |
| 0.2 | 1.3 | GO:0008440 | inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440) |
| 0.2 | 1.6 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.2 | 0.5 | GO:0008511 | sodium:potassium:chloride symporter activity(GO:0008511) |
| 0.2 | 5.3 | GO:0004129 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.2 | 6.4 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
| 0.2 | 1.2 | GO:0003689 | DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170) |
| 0.2 | 6.4 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.2 | 0.9 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
| 0.2 | 1.4 | GO:0046972 | histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972) |
| 0.2 | 2.5 | GO:0015643 | toxic substance binding(GO:0015643) |
| 0.2 | 13.5 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.2 | 4.7 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.2 | 2.4 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.2 | 1.9 | GO:0097027 | ubiquitin-protein transferase activator activity(GO:0097027) |
| 0.2 | 0.5 | GO:0070039 | rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039) |
| 0.1 | 2.4 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
| 0.1 | 0.4 | GO:0030620 | U2 snRNA binding(GO:0030620) |
| 0.1 | 0.9 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.1 | 1.7 | GO:0004065 | arylsulfatase activity(GO:0004065) |
| 0.1 | 0.6 | GO:0061628 | H3K27me3 modified histone binding(GO:0061628) |
| 0.1 | 1.4 | GO:0004972 | NMDA glutamate receptor activity(GO:0004972) |
| 0.1 | 0.7 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 0.1 | 0.5 | GO:0043515 | kinetochore binding(GO:0043515) |
| 0.1 | 0.4 | GO:0043739 | G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739) |
| 0.1 | 0.9 | GO:0008079 | translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079) |
| 0.1 | 0.8 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.1 | 0.8 | GO:0038052 | RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
| 0.1 | 0.5 | GO:0004449 | isocitrate dehydrogenase (NAD+) activity(GO:0004449) |
| 0.1 | 2.7 | GO:0031005 | filamin binding(GO:0031005) |
| 0.1 | 0.3 | GO:0080130 | L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130) |
| 0.1 | 7.1 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
| 0.1 | 1.0 | GO:0003958 | NADPH-hemoprotein reductase activity(GO:0003958) |
| 0.1 | 0.8 | GO:0004176 | ATP-dependent peptidase activity(GO:0004176) |
| 0.1 | 4.0 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.1 | 2.6 | GO:0005521 | lamin binding(GO:0005521) |
| 0.1 | 6.2 | GO:0031491 | nucleosome binding(GO:0031491) |
| 0.1 | 2.3 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.1 | 0.9 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.1 | 0.5 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.1 | 2.0 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.1 | 0.4 | GO:0004530 | deoxyribonuclease I activity(GO:0004530) |
| 0.1 | 1.3 | GO:0030332 | cyclin binding(GO:0030332) |
| 0.1 | 0.7 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.1 | 3.0 | GO:0048020 | CCR chemokine receptor binding(GO:0048020) |
| 0.1 | 0.2 | GO:0004939 | beta-adrenergic receptor activity(GO:0004939) |
| 0.1 | 1.2 | GO:0042809 | vitamin D receptor binding(GO:0042809) |
| 0.1 | 0.3 | GO:0015222 | serotonin transmembrane transporter activity(GO:0015222) |
| 0.1 | 0.3 | GO:0030197 | extracellular matrix constituent, lubricant activity(GO:0030197) |
| 0.1 | 1.6 | GO:0070628 | proteasome binding(GO:0070628) |
| 0.1 | 1.7 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.1 | 0.9 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.1 | 0.9 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.1 | 0.4 | GO:0005499 | vitamin D binding(GO:0005499) |
| 0.1 | 1.1 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
| 0.1 | 0.4 | GO:0030368 | interleukin-17 receptor activity(GO:0030368) |
| 0.1 | 6.1 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 0.3 | GO:0015319 | sodium:inorganic phosphate symporter activity(GO:0015319) |
| 0.1 | 0.3 | GO:0004464 | leukotriene-C4 synthase activity(GO:0004464) |
| 0.1 | 0.7 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.1 | 0.2 | GO:0044736 | acid-sensing ion channel activity(GO:0044736) |
| 0.1 | 1.0 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.1 | 0.7 | GO:0050693 | LBD domain binding(GO:0050693) |
| 0.0 | 1.9 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 0.5 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.0 | 0.7 | GO:0070324 | thyroid hormone binding(GO:0070324) |
| 0.0 | 0.6 | GO:0005221 | intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855) |
| 0.0 | 0.1 | GO:0004662 | CAAX-protein geranylgeranyltransferase activity(GO:0004662) |
| 0.0 | 2.9 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 2.0 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.0 | 3.0 | GO:0070063 | RNA polymerase binding(GO:0070063) |
| 0.0 | 1.2 | GO:0031418 | L-ascorbic acid binding(GO:0031418) |
| 0.0 | 1.0 | GO:0052629 | phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629) |
| 0.0 | 0.3 | GO:0004873 | asialoglycoprotein receptor activity(GO:0004873) |
| 0.0 | 0.1 | GO:0017153 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) sodium:dicarboxylate symporter activity(GO:0017153) |
| 0.0 | 3.3 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.0 | 2.1 | GO:0003954 | NADH dehydrogenase activity(GO:0003954) NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.0 | 0.2 | GO:0031962 | mineralocorticoid receptor binding(GO:0031962) |
| 0.0 | 0.4 | GO:0035005 | 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005) |
| 0.0 | 0.9 | GO:0005095 | GTPase inhibitor activity(GO:0005095) |
| 0.0 | 0.5 | GO:0004679 | AMP-activated protein kinase activity(GO:0004679) |
| 0.0 | 7.7 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 0.9 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 0.9 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.0 | 1.3 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 0.4 | GO:0004705 | JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909) |
| 0.0 | 0.2 | GO:0031433 | telethonin binding(GO:0031433) |
| 0.0 | 1.6 | GO:0050681 | androgen receptor binding(GO:0050681) |
| 0.0 | 1.7 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 0.7 | GO:0008175 | tRNA methyltransferase activity(GO:0008175) |
| 0.0 | 0.4 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
| 0.0 | 0.1 | GO:0035368 | selenocysteine insertion sequence binding(GO:0035368) |
| 0.0 | 1.4 | GO:0048487 | beta-tubulin binding(GO:0048487) |
| 0.0 | 0.5 | GO:0003678 | DNA helicase activity(GO:0003678) |
| 0.0 | 1.5 | GO:0043022 | ribosome binding(GO:0043022) |
| 0.0 | 0.9 | GO:0051059 | NF-kappaB binding(GO:0051059) |
| 0.0 | 3.1 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.4 | GO:0050786 | RAGE receptor binding(GO:0050786) |
| 0.0 | 0.2 | GO:0003810 | protein-glutamine gamma-glutamyltransferase activity(GO:0003810) |
| 0.0 | 1.3 | GO:0042805 | actinin binding(GO:0042805) |
| 0.0 | 2.6 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.0 | 0.7 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 2.1 | GO:0036459 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.0 | 1.6 | GO:0032813 | tumor necrosis factor receptor superfamily binding(GO:0032813) |
| 0.0 | 0.5 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.0 | 1.2 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.0 | 0.1 | GO:0000182 | rDNA binding(GO:0000182) |
| 0.0 | 0.5 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |
| 0.0 | 0.8 | GO:0004527 | exonuclease activity(GO:0004527) |
| 0.0 | 0.4 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 1.2 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.5 | GO:0008536 | Ran GTPase binding(GO:0008536) |
| 0.0 | 0.2 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.0 | 0.0 | GO:0052798 | beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798) |
| 0.0 | 0.3 | GO:0004993 | G-protein coupled serotonin receptor activity(GO:0004993) |
| 0.0 | 2.0 | GO:0000149 | SNARE binding(GO:0000149) |
| 0.0 | 0.3 | GO:0015929 | hexosaminidase activity(GO:0015929) |
| 0.0 | 0.2 | GO:0035497 | cAMP response element binding(GO:0035497) |
| 0.0 | 0.1 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.0 | 1.4 | GO:0004497 | monooxygenase activity(GO:0004497) |
| 0.0 | 1.1 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.0 | 2.7 | GO:0001047 | core promoter binding(GO:0001047) |
| 0.0 | 0.2 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.0 | 0.1 | GO:0015183 | L-aspartate transmembrane transporter activity(GO:0015183) |
| 0.0 | 0.5 | GO:0004890 | GABA-A receptor activity(GO:0004890) |
| 0.0 | 1.1 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.0 | 0.2 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.0 | 0.2 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
| 0.0 | 3.1 | GO:0003713 | transcription coactivator activity(GO:0003713) |
| 0.0 | 0.3 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.0 | 0.3 | GO:0005031 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.0 | 2.6 | GO:0005516 | calmodulin binding(GO:0005516) |
| 0.0 | 0.5 | GO:0004114 | 3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114) |
| 0.0 | 0.3 | GO:0015248 | sterol transporter activity(GO:0015248) |
| 0.0 | 1.5 | GO:0008168 | methyltransferase activity(GO:0008168) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.3 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.1 | 5.7 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
| 0.1 | 3.2 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.1 | 4.0 | PID WNT CANONICAL PATHWAY | Canonical Wnt signaling pathway |
| 0.1 | 2.1 | SA REG CASCADE OF CYCLIN EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
| 0.1 | 1.4 | PID BCR 5PATHWAY | BCR signaling pathway |
| 0.1 | 3.4 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 2.7 | PID HDAC CLASSIII PATHWAY | Signaling events mediated by HDAC Class III |
| 0.1 | 3.7 | PID FRA PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
| 0.1 | 14.5 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 3.0 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.1 | 3.6 | SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES | Genes related to regulation of the actin cytoskeleton |
| 0.1 | 1.4 | PID P53 REGULATION PATHWAY | p53 pathway |
| 0.1 | 0.8 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
| 0.0 | 1.3 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.0 | 1.6 | PID IL23 PATHWAY | IL23-mediated signaling events |
| 0.0 | 4.3 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.0 | 1.8 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.0 | 2.7 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.0 | 4.6 | PID CMYB PATHWAY | C-MYB transcription factor network |
| 0.0 | 3.3 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.9 | PID HEDGEHOG 2PATHWAY | Signaling events mediated by the Hedgehog family |
| 0.0 | 0.2 | PID TCR RAS PATHWAY | Ras signaling in the CD4+ TCR pathway |
| 0.0 | 3.8 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 1.5 | PID RXR VDR PATHWAY | RXR and RAR heterodimerization with other nuclear receptor |
| 0.0 | 1.1 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 8.2 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 5.4 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 2.1 | PID BETA CATENIN NUC PATHWAY | Regulation of nuclear beta catenin signaling and target gene transcription |
| 0.0 | 1.1 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.0 | 1.0 | PID FCER1 PATHWAY | Fc-epsilon receptor I signaling in mast cells |
| 0.0 | 1.0 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.0 | 1.2 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 0.7 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.0 | 0.5 | SIG CD40PATHWAYMAP | Genes related to CD40 signaling |
| 0.0 | 1.7 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 0.8 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
| 0.0 | 0.7 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
| 0.0 | 0.9 | PID ARF6 PATHWAY | Arf6 signaling events |
| 0.0 | 0.6 | PID RB 1PATHWAY | Regulation of retinoblastoma protein |
| 0.0 | 0.6 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.0 | 0.4 | ST JNK MAPK PATHWAY | JNK MAPK Pathway |
| 0.0 | 0.3 | PID SYNDECAN 2 PATHWAY | Syndecan-2-mediated signaling events |
| 0.0 | 4.3 | NABA MATRISOME ASSOCIATED | Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors |
| 0.0 | 0.1 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 5.5 | REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE | Genes involved in mRNA Decay by 3' to 5' Exoribonuclease |
| 0.4 | 6.8 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
| 0.3 | 6.2 | REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.2 | 8.4 | REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
| 0.2 | 4.0 | REACTOME MTORC1 MEDIATED SIGNALLING | Genes involved in mTORC1-mediated signalling |
| 0.2 | 3.7 | REACTOME INITIAL TRIGGERING OF COMPLEMENT | Genes involved in Initial triggering of complement |
| 0.2 | 6.8 | REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
| 0.1 | 1.3 | REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
| 0.1 | 2.0 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.1 | 1.4 | REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS | Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers |
| 0.1 | 3.1 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.1 | 1.4 | REACTOME PASSIVE TRANSPORT BY AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.1 | 0.7 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.1 | 16.4 | REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION | Genes involved in 3' -UTR-mediated translational regulation |
| 0.1 | 3.1 | REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS | Genes involved in Activation of ATR in response to replication stress |
| 0.1 | 1.3 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.1 | 3.4 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.1 | 2.1 | REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.1 | 1.5 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.1 | 2.1 | REACTOME METABOLISM OF PORPHYRINS | Genes involved in Metabolism of porphyrins |
| 0.1 | 0.7 | REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING | Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling |
| 0.1 | 5.7 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.1 | 2.2 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |
| 0.1 | 1.1 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.1 | 0.6 | REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS | Genes involved in Post-translational modification: synthesis of GPI-anchored proteins |
| 0.1 | 4.0 | REACTOME GLUCONEOGENESIS | Genes involved in Gluconeogenesis |
| 0.1 | 0.8 | REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC | Genes involved in Formation of tubulin folding intermediates by CCT/TriC |
| 0.1 | 0.9 | REACTOME RETROGRADE NEUROTROPHIN SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.1 | 1.2 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |
| 0.1 | 0.5 | REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES | Genes involved in Recruitment of NuMA to mitotic centrosomes |
| 0.1 | 1.3 | REACTOME GLUCURONIDATION | Genes involved in Glucuronidation |
| 0.1 | 1.4 | REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
| 0.1 | 2.8 | REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING | Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening |
| 0.0 | 1.7 | REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
| 0.0 | 0.6 | REACTOME ACYL CHAIN REMODELLING OF PS | Genes involved in Acyl chain remodelling of PS |
| 0.0 | 0.6 | REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX | Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex |
| 0.0 | 1.2 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 1.8 | REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE | Genes involved in Synthesis of PIPs at the plasma membrane |
| 0.0 | 0.9 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 1.0 | REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.0 | 0.5 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |
| 0.0 | 0.5 | REACTOME MRNA SPLICING MINOR PATHWAY | Genes involved in mRNA Splicing - Minor Pathway |
| 0.0 | 0.4 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.0 | 0.2 | REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 0.0 | 1.6 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.0 | 0.5 | REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY | Genes involved in TRAF3-dependent IRF activation pathway |
| 0.0 | 1.3 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.0 | 2.3 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 1.9 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.0 | 0.4 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |
| 0.0 | 2.1 | REACTOME MUSCLE CONTRACTION | Genes involved in Muscle contraction |
| 0.0 | 0.2 | REACTOME PLATELET SENSITIZATION BY LDL | Genes involved in Platelet sensitization by LDL |
| 0.0 | 0.4 | REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 | Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 |
| 0.0 | 0.7 | REACTOME RECRUITMENT OF MITOTIC CENTROSOME PROTEINS AND COMPLEXES | Genes involved in Recruitment of mitotic centrosome proteins and complexes |
| 0.0 | 1.5 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.0 | 0.3 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.0 | 0.1 | REACTOME PROLONGED ERK ACTIVATION EVENTS | Genes involved in Prolonged ERK activation events |
| 0.0 | 0.8 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.5 | REACTOME ION TRANSPORT BY P TYPE ATPASES | Genes involved in Ion transport by P-type ATPases |