ISMARA results: EZH2

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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for EZH2

Z-value: 8.85

Motif logo

Transcription factors associated with EZH2

Gene Symbol	Gene ID	Gene Info
EZH2 Ensembl NCBI GeneCards UniProt	ENSG00000106462.12	EZH2

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
EZH2	hg38_v1_chr7_-_148883474_148883509	-0.64	7.7e-27	Click!

Activity profile of EZH2 motif

Sorted Z-values of EZH2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EZH2

View svg image
View png image

Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr11_-_111910888 Show fit	81.90	ENST00000525823.1 ENST00000528961.6	CRYAB Ensembl NCBI GeneCards UniProt Show fit	crystallin alpha B
chr11_-_111910790 Show fit	75.23	ENST00000533280.6	CRYAB Ensembl NCBI GeneCards UniProt Show fit	crystallin alpha B
chr11_-_111910830 Show fit	73.21	ENST00000526167.5 ENST00000651650.1	CRYAB Ensembl NCBI GeneCards UniProt Show fit	crystallin alpha B
chr3_+_115623502 Show fit	57.00	ENST00000305124.11 ENST00000393780.3	GAP43 Ensembl NCBI GeneCards UniProt Show fit	growth associated protein 43
chr17_+_7650916 Show fit	38.08	ENST00000250111.9	ATP1B2 Ensembl NCBI GeneCards UniProt Show fit	ATPase Na+/K+ transporting subunit beta 2
chr7_+_140404034 Show fit	35.88	ENST00000537763.6	RAB19 Ensembl NCBI GeneCards UniProt Show fit	RAB19, member RAS oncogene family
chr6_-_73452124 Show fit	35.65	ENST00000680833.1	CGAS Ensembl NCBI GeneCards UniProt Show fit	cyclic GMP-AMP synthase
chrX_+_70062457 Show fit	35.08	ENST00000338352.3	OTUD6A Ensembl NCBI GeneCards UniProt Show fit	OTU deubiquitinase 6A
chr3_-_195583931 Show fit	32.80	ENST00000343267.8 ENST00000421243.5 ENST00000453131.1	APOD Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein D
chr4_-_16898561 Show fit	32.71	ENST00000515064.5 ENST00000441778.6	LDB2 Ensembl NCBI GeneCards UniProt Show fit	LIM domain binding 2
chr16_+_7304219 Show fit	32.51	ENST00000675562.1	RBFOX1 Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr11_-_133532493 Show fit	31.02	ENST00000524381.6	OPCML Ensembl NCBI GeneCards UniProt Show fit	opioid binding protein/cell adhesion molecule like
chr14_-_21022817 Show fit	28.46	ENST00000554104.5	NDRG2 Ensembl NCBI GeneCards UniProt Show fit	NDRG family member 2
chr13_-_67230377 Show fit	27.60	ENST00000544246.5 ENST00000377861.4	PCDH9 Ensembl NCBI GeneCards UniProt Show fit	protocadherin 9
chr7_+_121873317 Show fit	27.53	ENST00000651863.1 ENST00000652298.1 ENST00000449182.1	PTPRZ1 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase receptor type Z1
chr11_-_111911759 Show fit	27.50	ENST00000650687.2	CRYAB Ensembl NCBI GeneCards UniProt Show fit	crystallin alpha B
chr8_+_22059198 Show fit	27.13	ENST00000523266.5 ENST00000519907.5	DMTN Ensembl NCBI GeneCards UniProt Show fit	dematin actin binding protein
chr13_-_67230313 Show fit	26.93	ENST00000377865.7	PCDH9 Ensembl NCBI GeneCards UniProt Show fit	protocadherin 9
chr1_+_160127672 Show fit	26.84	ENST00000447527.1	ATP1A2 Ensembl NCBI GeneCards UniProt Show fit	ATPase Na+/K+ transporting subunit alpha 2
chrX_-_13817346 Show fit	26.30	ENST00000356942.9	GPM6B Ensembl NCBI GeneCards UniProt Show fit	glycoprotein M6B
chr8_+_79611036 Show fit	26.24	ENST00000220876.12 ENST00000518111.5	STMN2 Ensembl NCBI GeneCards UniProt Show fit	stathmin 2
chr16_+_7303245 Show fit	26.09	ENST00000674626.1	RBFOX1 Ensembl NCBI GeneCards UniProt Show fit	RNA binding fox-1 homolog 1
chr5_-_160685379 Show fit	25.56	ENST00000642502.1	ATP10B Ensembl NCBI GeneCards UniProt Show fit	ATPase phospholipid transporting 10B (putative)
chr19_-_36032799 Show fit	24.19	ENST00000592017.5 ENST00000360535.9	CLIP3 Ensembl NCBI GeneCards UniProt Show fit	CAP-Gly domain containing linker protein 3
chr3_-_58587033 Show fit	23.83	ENST00000447756.2	FAM107A Ensembl NCBI GeneCards UniProt Show fit	family with sequence similarity 107 member A
chr14_-_21022494 Show fit	23.79	ENST00000449431.6	NDRG2 Ensembl NCBI GeneCards UniProt Show fit	NDRG family member 2
chrX_+_103776831 Show fit	23.56	ENST00000621218.5 ENST00000619236.1	PLP1 Ensembl NCBI GeneCards UniProt Show fit	proteolipid protein 1
chrX_+_103776493 Show fit	23.48	ENST00000433491.5 ENST00000612423.4 ENST00000443502.5	PLP1 Ensembl NCBI GeneCards UniProt Show fit	proteolipid protein 1
chr2_-_50347789 Show fit	22.90	ENST00000628364.2	NRXN1 Ensembl NCBI GeneCards UniProt Show fit	neurexin 1
chr5_-_147081428 Show fit	22.23	ENST00000394413.7	PPP2R2B Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 2 regulatory subunit Bbeta
chr15_+_43593054 Show fit	21.25	ENST00000453782.5 ENST00000300283.10 ENST00000437924.5	CKMT1B Ensembl NCBI GeneCards UniProt Show fit	creatine kinase, mitochondrial 1B
chr7_+_121873478 Show fit	21.24	ENST00000651320.1	PTPRZ1 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase receptor type Z1
chr12_-_44876294 Show fit	21.21	ENST00000429094.7 ENST00000551601.5 ENST00000549027.5 ENST00000452445.6	NELL2 Ensembl NCBI GeneCards UniProt Show fit	neural EGFL like 2
chr15_+_43517590 Show fit	21.20	ENST00000300231.6	MAP1A Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 1A
chr4_+_157220654 Show fit	21.12	ENST00000393815.6	GRIA2 Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor AMPA type subunit 2
chr8_+_79611727 Show fit	20.51	ENST00000518491.1	STMN2 Ensembl NCBI GeneCards UniProt Show fit	stathmin 2
chr14_-_21023144 Show fit	20.36	ENST00000554531.5	NDRG2 Ensembl NCBI GeneCards UniProt Show fit	NDRG family member 2
chr14_-_21022432 Show fit	20.34	ENST00000557633.5	NDRG2 Ensembl NCBI GeneCards UniProt Show fit	NDRG family member 2
chr8_-_27611424 Show fit	20.21	ENST00000405140.7	CLU Ensembl NCBI GeneCards UniProt Show fit	clusterin
chr1_-_56579555 Show fit	20.00	ENST00000371250.4	PLPP3 Ensembl NCBI GeneCards UniProt Show fit	phospholipid phosphatase 3
chr5_+_141359970 Show fit	19.92	ENST00000522605.2 ENST00000622527.1	PCDHGB2 Ensembl NCBI GeneCards UniProt Show fit	protocadherin gamma subfamily B, 2
chr1_-_163202835 Show fit	19.48	ENST00000527988.1 ENST00000531476.1 ENST00000530507.5 ENST00000313961.10	RGS5 Ensembl NCBI GeneCards UniProt Show fit	regulator of G protein signaling 5
chr15_+_43594027 Show fit	19.04	ENST00000453733.5 ENST00000441322.6 ENST00000627381.1	CKMT1B Ensembl NCBI GeneCards UniProt Show fit	creatine kinase, mitochondrial 1B
chr8_-_18808837 Show fit	18.93	ENST00000286485.12	PSD3 Ensembl NCBI GeneCards UniProt Show fit	pleckstrin and Sec7 domain containing 3
chr17_-_7219813 Show fit	18.88	ENST00000399510.8 ENST00000648172.8	DLG4 Ensembl NCBI GeneCards UniProt Show fit	discs large MAGUK scaffold protein 4
chr6_-_166627244 Show fit	18.71	ENST00000265678.9	RPS6KA2 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A2
chr12_-_50167292 Show fit	18.42	ENST00000547800.2 ENST00000317551.12 ENST00000422340.6	CERS5 Ensembl NCBI GeneCards UniProt Show fit	ceramide synthase 5
chr15_+_43693859 Show fit	18.35	ENST00000413453.7 ENST00000415044.3 ENST00000626814.1	CKMT1A Ensembl NCBI GeneCards UniProt Show fit	creatine kinase, mitochondrial 1A
chr8_+_22059169 Show fit	18.34	ENST00000358242.5	DMTN Ensembl NCBI GeneCards UniProt Show fit	dematin actin binding protein
chr6_-_6006878 Show fit	18.15	ENST00000244766.7	NRN1 Ensembl NCBI GeneCards UniProt Show fit	neuritin 1
chr12_-_44875647 Show fit	17.98	ENST00000395487.6	NELL2 Ensembl NCBI GeneCards UniProt Show fit	neural EGFL like 2
chr14_-_44961889 Show fit	17.92	ENST00000579157.1 ENST00000396128.9 ENST00000556500.1	KLHL28 Ensembl NCBI GeneCards UniProt Show fit	kelch like family member 28
chr21_+_25639251 Show fit	17.81	ENST00000480456.6	JAM2 Ensembl NCBI GeneCards UniProt Show fit	junctional adhesion molecule 2
chr14_-_21022258 Show fit	17.53	ENST00000556366.5	NDRG2 Ensembl NCBI GeneCards UniProt Show fit	NDRG family member 2
chr4_+_24795560 Show fit	17.43	ENST00000382120.4	SOD3 Ensembl NCBI GeneCards UniProt Show fit	superoxide dismutase 3
chr11_-_113875555 Show fit	17.42	ENST00000003302.8 ENST00000545540.5	USP28 Ensembl NCBI GeneCards UniProt Show fit	ubiquitin specific peptidase 28
chr14_-_75981986 Show fit	17.35	ENST00000238682.8	TGFB3 Ensembl NCBI GeneCards UniProt Show fit	transforming growth factor beta 3
chr6_-_73452253 Show fit	17.00	ENST00000370318.5 ENST00000370315.4	CGAS Ensembl NCBI GeneCards UniProt Show fit	cyclic GMP-AMP synthase
chr7_-_22193728 Show fit	16.81	ENST00000620335.4	RAPGEF5 Ensembl NCBI GeneCards UniProt Show fit	Rap guanine nucleotide exchange factor 5
chr12_-_91182784 Show fit	16.72	ENST00000547568.6 ENST00000052754.10 ENST00000552962.5	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr12_+_6821797 Show fit	16.60	ENST00000311268.8 ENST00000382315.7	GPR162 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 162
chr14_-_20802402 Show fit	16.44	ENST00000412779.2	RNASE1 Ensembl NCBI GeneCards UniProt Show fit	ribonuclease A family member 1, pancreatic
chr4_-_16898619 Show fit	16.22	ENST00000502640.5 ENST00000304523.10 ENST00000506732.1	LDB2 Ensembl NCBI GeneCards UniProt Show fit	LIM domain binding 2
chr9_+_121299793 Show fit	16.08	ENST00000373818.8	GSN Ensembl NCBI GeneCards UniProt Show fit	gelsolin
chr15_+_78438279 Show fit	15.80	ENST00000560440.5	IREB2 Ensembl NCBI GeneCards UniProt Show fit	iron responsive element binding protein 2
chr12_-_91182652 Show fit	15.77	ENST00000552145.5 ENST00000546745.5	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr11_-_66958366 Show fit	15.60	ENST00000651036.1 ENST00000652125.1 ENST00000531614.6 ENST00000524491.6 ENST00000529047.6 ENST00000393960.7 ENST00000393958.7 ENST00000528403.6 ENST00000651854.1	PC Ensembl NCBI GeneCards UniProt Show fit	pyruvate carboxylase
chr19_-_48646155 Show fit	15.44	ENST00000084798.9	CA11 Ensembl NCBI GeneCards UniProt Show fit	carbonic anhydrase 11
chr6_-_109440504 Show fit	15.37	ENST00000520723.5 ENST00000518648.1 ENST00000417394.6 ENST00000521072.7	PPIL6 Ensembl NCBI GeneCards UniProt Show fit	peptidylprolyl isomerase like 6
chr17_-_48590231 Show fit	15.22	ENST00000476342.1 ENST00000460160.5 ENST00000498678.6 ENST00000472863.5	HOXB3 Ensembl NCBI GeneCards UniProt Show fit	homeobox B3
chr1_-_230714112 Show fit	15.11	ENST00000681514.1 ENST00000366667.6 ENST00000680041.1	AGT Ensembl NCBI GeneCards UniProt Show fit	angiotensinogen
chr19_-_41994079 Show fit	15.00	ENST00000602133.5	ATP1A3 Ensembl NCBI GeneCards UniProt Show fit	ATPase Na+/K+ transporting subunit alpha 3
chr4_+_157220691 Show fit	14.92	ENST00000509417.5 ENST00000645636.1 ENST00000296526.12 ENST00000264426.14	GRIA2 Ensembl NCBI GeneCards UniProt Show fit	glutamate ionotropic receptor AMPA type subunit 2
chr12_+_6821646 Show fit	14.89	ENST00000428545.6	GPR162 Ensembl NCBI GeneCards UniProt Show fit	G protein-coupled receptor 162
chr1_-_177164673 Show fit	14.80	ENST00000424564.2 ENST00000361833.7	ASTN1 Ensembl NCBI GeneCards UniProt Show fit	astrotactin 1
chr16_+_31074390 Show fit	14.54	ENST00000300850.5 ENST00000564189.1 ENST00000428260.1	ZNF646 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 646
chr2_+_209424039 Show fit	14.51	ENST00000682079.1 ENST00000199940.10	MAP2 Ensembl NCBI GeneCards UniProt Show fit	microtubule associated protein 2
chr1_+_209686173 Show fit	14.28	ENST00000615289.4 ENST00000367028.6 ENST00000261465.5	HSD11B1 Ensembl NCBI GeneCards UniProt Show fit	hydroxysteroid 11-beta dehydrogenase 1
chr2_-_68157470 Show fit	14.20	ENST00000406245.6 ENST00000409164.1 ENST00000295121.11	WDR92 Ensembl NCBI GeneCards UniProt Show fit	WD repeat domain 92
chr2_-_127107144 Show fit	14.19	ENST00000316724.10	BIN1 Ensembl NCBI GeneCards UniProt Show fit	bridging integrator 1
chr5_+_161848536 Show fit	14.10	ENST00000519621.2 ENST00000636573.1	GABRA1 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit alpha1
chr3_+_147409357 Show fit	14.02	ENST00000282928.5	ZIC1 Ensembl NCBI GeneCards UniProt Show fit	Zic family member 1
chr5_-_147081462 Show fit	14.00	ENST00000508267.5 ENST00000504198.5	PPP2R2B Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 2 regulatory subunit Bbeta
chr14_-_20802836 Show fit	13.85	ENST00000397967.5 ENST00000555698.5 ENST00000397970.4 ENST00000340900.3	RNASE1 Ensembl NCBI GeneCards UniProt Show fit	ribonuclease A family member 1, pancreatic
chr12_-_54588636 Show fit	13.82	ENST00000257905.13	PPP1R1A Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory inhibitor subunit 1A
chr19_+_35140022 Show fit	13.78	ENST00000588081.5 ENST00000589121.1	FXYD1 Ensembl NCBI GeneCards UniProt Show fit	FXYD domain containing ion transport regulator 1
chr16_-_21278282 Show fit	13.74	ENST00000572914.2	CRYM Ensembl NCBI GeneCards UniProt Show fit	crystallin mu
chr18_-_55510753 Show fit	13.50	ENST00000543082.5	TCF4 Ensembl NCBI GeneCards UniProt Show fit	transcription factor 4
chr5_+_161848314 Show fit	13.49	ENST00000437025.6	GABRA1 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit alpha1
chr7_+_129611680 Show fit	13.45	ENST00000393232.6 ENST00000454688.5 ENST00000223190.8 ENST00000311967.6	NRF1 Ensembl NCBI GeneCards UniProt Show fit	nuclear respiratory factor 1
chr6_+_43576119 Show fit	13.30	ENST00000372236.9	POLH Ensembl NCBI GeneCards UniProt Show fit	DNA polymerase eta
chr14_+_92323154 Show fit	13.24	ENST00000532405.6 ENST00000676001.1 ENST00000531433.5	SLC24A4 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 24 member 4
chr12_-_54588516 Show fit	13.21	ENST00000547431.5	PPP1R1A Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory inhibitor subunit 1A
chr5_-_20575850 Show fit	13.21	ENST00000507958.5	CDH18 Ensembl NCBI GeneCards UniProt Show fit	cadherin 18
chr11_-_66729184 Show fit	13.19	ENST00000533211.6 ENST00000309996.7	SPTBN2 Ensembl NCBI GeneCards UniProt Show fit	spectrin beta, non-erythrocytic 2
chr21_+_25639272 Show fit	13.08	ENST00000400532.5 ENST00000312957.9	JAM2 Ensembl NCBI GeneCards UniProt Show fit	junctional adhesion molecule 2
chr8_-_126558461 Show fit	12.93	ENST00000304916.4	LRATD2 Ensembl NCBI GeneCards UniProt Show fit	LRAT domain containing 2
chr6_-_166862502 Show fit	12.83	ENST00000510118.5 ENST00000503859.5 ENST00000506565.1	RPS6KA2 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A2
chr15_+_43692886 Show fit	12.82	ENST00000434505.5 ENST00000411750.5	CKMT1A Ensembl NCBI GeneCards UniProt Show fit	creatine kinase, mitochondrial 1A
chr1_+_151070740 Show fit	12.82	ENST00000368918.8	GABPB2 Ensembl NCBI GeneCards UniProt Show fit	GA binding protein transcription factor subunit beta 2
chr14_+_44962177 Show fit	12.77	ENST00000361462.7 ENST00000361577.7	TOGARAM1 Ensembl NCBI GeneCards UniProt Show fit	TOG array regulator of axonemal microtubules 1
chr16_-_29899532 Show fit	12.77	ENST00000308713.9 ENST00000617533.5	SEZ6L2 Ensembl NCBI GeneCards UniProt Show fit	seizure related 6 homolog like 2
chr2_-_218010202 Show fit	12.76	ENST00000646520.1	TNS1 Ensembl NCBI GeneCards UniProt Show fit	tensin 1
chr7_-_100428657 Show fit	12.72	ENST00000360951.8 ENST00000398027.6 ENST00000684423.1 ENST00000472716.1	ZCWPW1 Ensembl NCBI GeneCards UniProt Show fit	zinc finger CW-type and PWWP domain containing 1
chr11_-_123654939 Show fit	12.72	ENST00000657191.1	SCN3B Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel beta subunit 3
chr6_+_31982057 Show fit	12.69	ENST00000428956.7 ENST00000498271.1	C4A Ensembl NCBI GeneCards UniProt Show fit	complement C4A (Rodgers blood group)
chr8_-_27258414 Show fit	12.66	ENST00000523048.5	STMN4 Ensembl NCBI GeneCards UniProt Show fit	stathmin 4
chr16_-_970847 Show fit	12.54	ENST00000568897.5	LMF1 Ensembl NCBI GeneCards UniProt Show fit	lipase maturation factor 1
chr8_+_19939246 Show fit	12.52	ENST00000650287.1	LPL Ensembl NCBI GeneCards UniProt Show fit	lipoprotein lipase
chr19_+_42076129 Show fit	12.52	ENST00000359044.5	ZNF574 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 574
chr7_-_122886706 Show fit	12.46	ENST00000313070.11 ENST00000334010.11 ENST00000615869.4	CADPS2 Ensembl NCBI GeneCards UniProt Show fit	calcium dependent secretion activator 2
chr17_+_28357638 Show fit	12.42	ENST00000292114.8 ENST00000591482.1	TMEM199 Ensembl NCBI GeneCards UniProt Show fit ENSG00000258924.4 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 199 novel transcript readthrough between TMEM199 and SARM1
chr1_-_201373229 Show fit	12.35	ENST00000367317.8 ENST00000360372.8 ENST00000236918.11 ENST00000367315.6 ENST00000658476.1	TNNT2 Ensembl NCBI GeneCards UniProt Show fit	troponin T2, cardiac type
chr6_+_19837362 Show fit	12.32	ENST00000378700.8	ID4 Ensembl NCBI GeneCards UniProt Show fit	inhibitor of DNA binding 4, HLH protein
chr16_+_66880503 Show fit	12.26	ENST00000568869.1 ENST00000311765.4 ENST00000561704.1 ENST00000568398.1 ENST00000566776.1	PDP2 Ensembl NCBI GeneCards UniProt Show fit	pyruvate dehyrogenase phosphatase catalytic subunit 2
chr6_+_29656993 Show fit	12.18	ENST00000376888.6	MOG Ensembl NCBI GeneCards UniProt Show fit	myelin oligodendrocyte glycoprotein
chr4_-_76023489 Show fit	12.17	ENST00000306602.3	CXCL10 Ensembl NCBI GeneCards UniProt Show fit	C-X-C motif chemokine ligand 10
chr16_-_31074193 Show fit	12.11	ENST00000300849.5	ZNF668 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 668
chr11_-_117295485 Show fit	12.07	ENST00000680971.1	BACE1 Ensembl NCBI GeneCards UniProt Show fit	beta-secretase 1
chr2_-_69643703 Show fit	12.00	ENST00000406297.7 ENST00000409085.9	AAK1 Ensembl NCBI GeneCards UniProt Show fit	AP2 associated kinase 1
chr1_-_72282457 Show fit	11.94	ENST00000357731.10	NEGR1 Ensembl NCBI GeneCards UniProt Show fit	neuronal growth regulator 1
chr8_+_26577843 Show fit	11.93	ENST00000311151.9	DPYSL2 Ensembl NCBI GeneCards UniProt Show fit	dihydropyrimidinase like 2
chr14_+_74084947 Show fit	11.92	ENST00000674221.1 ENST00000554938.2	LIN52 Ensembl NCBI GeneCards UniProt Show fit	lin-52 DREAM MuvB core complex component
chr1_+_156619406 Show fit	11.86	ENST00000255039.6 ENST00000456112.1	HAPLN2 Ensembl NCBI GeneCards UniProt Show fit	hyaluronan and proteoglycan link protein 2
chr5_+_93583212 Show fit	11.81	ENST00000327111.8	NR2F1 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 2 group F member 1
chr1_-_149917826 Show fit	11.80	ENST00000369145.1 ENST00000369146.8	SV2A Ensembl NCBI GeneCards UniProt Show fit	synaptic vesicle glycoprotein 2A
chr7_-_101200912 Show fit	11.79	ENST00000440203.6 ENST00000379423.3 ENST00000223114.9	MOGAT3 Ensembl NCBI GeneCards UniProt Show fit	monoacylglycerol O-acyltransferase 3
chr6_+_29657085 Show fit	11.66	ENST00000376917.8 ENST00000376894.8	MOG Ensembl NCBI GeneCards UniProt Show fit	myelin oligodendrocyte glycoprotein
chr3_+_29281049 Show fit	11.64	ENST00000383767.7	RBMS3 Ensembl NCBI GeneCards UniProt Show fit	RNA binding motif single stranded interacting protein 3
chr2_+_104854104 Show fit	11.54	ENST00000361360.4	POU3F3 Ensembl NCBI GeneCards UniProt Show fit	POU class 3 homeobox 3
chr22_-_50085414 Show fit	11.53	ENST00000311597.10	MLC1 Ensembl NCBI GeneCards UniProt Show fit	modulator of VRAC current 1
chr1_+_2073462 Show fit	11.45	ENST00000400921.6	PRKCZ Ensembl NCBI GeneCards UniProt Show fit	protein kinase C zeta
chr19_+_35292125 Show fit	11.42	ENST00000600291.5 ENST00000361922.8	MAG Ensembl NCBI GeneCards UniProt Show fit	myelin associated glycoprotein
chr6_+_43576205 Show fit	11.31	ENST00000372226.1 ENST00000443535.1	POLH Ensembl NCBI GeneCards UniProt Show fit	DNA polymerase eta
chr8_-_27258386 Show fit	11.30	ENST00000350889.8 ENST00000519997.5 ENST00000519614.5 ENST00000522908.1 ENST00000265770.11	STMN4 Ensembl NCBI GeneCards UniProt Show fit	stathmin 4
chr3_-_112641128 Show fit	11.21	ENST00000206423.8	CCDC80 Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 80
chr7_-_137343688 Show fit	11.14	ENST00000348225.7	PTN Ensembl NCBI GeneCards UniProt Show fit	pleiotrophin
chr11_+_27040725 Show fit	11.11	ENST00000529202.5 ENST00000263182.8	BBOX1 Ensembl NCBI GeneCards UniProt Show fit	gamma-butyrobetaine hydroxylase 1
chr14_-_53153098 Show fit	11.11	ENST00000612692.4 ENST00000395606.5	DDHD1 Ensembl NCBI GeneCards UniProt Show fit	DDHD domain containing 1
chr5_+_36608146 Show fit	11.11	ENST00000381918.4 ENST00000513646.1	SLC1A3 Ensembl NCBI GeneCards UniProt Show fit	solute carrier family 1 member 3
chr8_-_56446572 Show fit	11.11	ENST00000518974.5 ENST00000451791.7 ENST00000523051.5 ENST00000518770.1	PENK Ensembl NCBI GeneCards UniProt Show fit	proenkephalin
chr4_+_155666827 Show fit	11.10	ENST00000511507.5 ENST00000506455.6	GUCY1A1 Ensembl NCBI GeneCards UniProt Show fit	guanylate cyclase 1 soluble subunit alpha 1
chr18_-_43115625 Show fit	11.09	ENST00000590910.1 ENST00000326695.10 ENST00000589109.5	RIT2 Ensembl NCBI GeneCards UniProt Show fit	Ras like without CAAX 2
chr5_-_134371004 Show fit	11.04	ENST00000521755.1 ENST00000523054.5 ENST00000518409.1	CDKL3 Ensembl NCBI GeneCards UniProt Show fit ENSG00000273345.5 Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase like 3 novel transcript
chr7_+_100539188 Show fit	10.94	ENST00000300176.9	AGFG2 Ensembl NCBI GeneCards UniProt Show fit	ArfGAP with FG repeats 2
chr15_+_43791842 Show fit	10.92	ENST00000674451.1 ENST00000630046.2	SERF2 Ensembl NCBI GeneCards UniProt Show fit	small EDRK-rich factor 2
chr5_-_74641419 Show fit	10.92	ENST00000618628.4 ENST00000510316.5 ENST00000508331.1	ENC1 Ensembl NCBI GeneCards UniProt Show fit	ectodermal-neural cortex 1
chr2_-_69643615 Show fit	10.86	ENST00000409068.5	AAK1 Ensembl NCBI GeneCards UniProt Show fit	AP2 associated kinase 1
chr11_-_72674394 Show fit	10.84	ENST00000418754.6 ENST00000334456.10 ENST00000542969.2	PDE2A Ensembl NCBI GeneCards UniProt Show fit	phosphodiesterase 2A
chr5_+_141350081 Show fit	10.84	ENST00000523390.2 ENST00000611598.1	PCDHGB1 Ensembl NCBI GeneCards UniProt Show fit	protocadherin gamma subfamily B, 1
chr18_+_74597850 Show fit	10.79	ENST00000582337.5 ENST00000299687.10	ZNF407 Ensembl NCBI GeneCards UniProt Show fit	zinc finger protein 407
chr6_+_29657120 Show fit	10.76	ENST00000396704.7 ENST00000416766.6 ENST00000483013.5 ENST00000490427.5 ENST00000376891.8 ENST00000376898.7 ENST00000396701.6 ENST00000494692.5 ENST00000431798.6	MOG Ensembl NCBI GeneCards UniProt Show fit	myelin oligodendrocyte glycoprotein
chr17_+_18315273 Show fit	10.74	ENST00000406438.5	SMCR8 Ensembl NCBI GeneCards UniProt Show fit	SMCR8-C9orf72 complex subunit
chr20_-_49278416 Show fit	10.66	ENST00000371754.8	ZNFX1 Ensembl NCBI GeneCards UniProt Show fit	zinc finger NFX1-type containing 1
chr10_+_17809337 Show fit	10.54	ENST00000569591.3	MRC1 Ensembl NCBI GeneCards UniProt Show fit	mannose receptor C-type 1
chr12_-_55707865 Show fit	10.51	ENST00000347027.10 ENST00000257879.11 ENST00000553804.6	ITGA7 Ensembl NCBI GeneCards UniProt Show fit	integrin subunit alpha 7
chr2_+_80305105 Show fit	10.49	ENST00000541047.5	CTNNA2 Ensembl NCBI GeneCards UniProt Show fit	catenin alpha 2
chr19_+_57231014 Show fit	10.45	ENST00000302804.12	AURKC Ensembl NCBI GeneCards UniProt Show fit	aurora kinase C
chr5_-_116536458 Show fit	10.40	ENST00000510263.5	SEMA6A Ensembl NCBI GeneCards UniProt Show fit	semaphorin 6A
chrX_-_139642835 Show fit	10.38	ENST00000536274.5	MCF2 Ensembl NCBI GeneCards UniProt Show fit	MCF.2 cell line derived transforming sequence
chr1_+_50108856 Show fit	10.38	ENST00000650764.1 ENST00000494555.2 ENST00000371824.7 ENST00000371823.8 ENST00000652693.1	ELAVL4 Ensembl NCBI GeneCards UniProt Show fit	ELAV like RNA binding protein 4
chr1_+_2073986 Show fit	10.32	ENST00000461106.6	PRKCZ Ensembl NCBI GeneCards UniProt Show fit	protein kinase C zeta
chr11_-_123654581 Show fit	10.31	ENST00000392770.6 ENST00000530277.5 ENST00000299333.8	SCN3B Ensembl NCBI GeneCards UniProt Show fit	sodium voltage-gated channel beta subunit 3
chr12_+_101594849 Show fit	10.26	ENST00000547405.5 ENST00000452455.6 ENST00000392934.7 ENST00000547509.5 ENST00000361685.6 ENST00000549145.5 ENST00000361466.7 ENST00000553190.5 ENST00000545503.6 ENST00000536007.5 ENST00000541119.5 ENST00000551300.5 ENST00000550270.1	MYBPC1 Ensembl NCBI GeneCards UniProt Show fit	myosin binding protein C1
chr6_+_125919296 Show fit	10.22	ENST00000444128.2	NCOA7 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor coactivator 7
chr20_-_54070520 Show fit	10.17	ENST00000371435.6 ENST00000395961.7	BCAS1 Ensembl NCBI GeneCards UniProt Show fit	brain enriched myelin associated protein 1
chr17_+_7484357 Show fit	10.04	ENST00000674977.2	POLR2A Ensembl NCBI GeneCards UniProt Show fit	RNA polymerase II subunit A
chr10_+_18340699 Show fit	10.04	ENST00000377329.10	CACNB2 Ensembl NCBI GeneCards UniProt Show fit	calcium voltage-gated channel auxiliary subunit beta 2
chrX_-_153794356 Show fit	10.03	ENST00000427365.6 ENST00000444450.5 ENST00000217901.10 ENST00000370093.5	IDH3G Ensembl NCBI GeneCards UniProt Show fit	isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
chr12_+_26195313 Show fit	10.02	ENST00000422622.3	SSPN Ensembl NCBI GeneCards UniProt Show fit	sarcospan
chr1_+_17580474 Show fit	10.02	ENST00000375415.5	ARHGEF10L Ensembl NCBI GeneCards UniProt Show fit	Rho guanine nucleotide exchange factor 10 like
chr7_+_121873089 Show fit	10.01	ENST00000651065.1	PTPRZ1 Ensembl NCBI GeneCards UniProt Show fit	protein tyrosine phosphatase receptor type Z1
chr8_-_21788853 Show fit	9.97	ENST00000524240.6	GFRA2 Ensembl NCBI GeneCards UniProt Show fit	GDNF family receptor alpha 2
chr12_+_112791738 Show fit	9.89	ENST00000389385.9	RPH3A Ensembl NCBI GeneCards UniProt Show fit	rabphilin 3A
chr2_+_218859794 Show fit	9.87	ENST00000233948.4	WNT6 Ensembl NCBI GeneCards UniProt Show fit	Wnt family member 6
chr5_-_11589019 Show fit	9.81	ENST00000511377.5	CTNND2 Ensembl NCBI GeneCards UniProt Show fit	catenin delta 2
chr1_-_155562693 Show fit	9.80	ENST00000368346.7 ENST00000392403.8 ENST00000679333.1 ENST00000679133.1	ASH1L Ensembl NCBI GeneCards UniProt Show fit	ASH1 like histone lysine methyltransferase
chr2_-_2326210 Show fit	9.79	ENST00000647755.1	MYT1L Ensembl NCBI GeneCards UniProt Show fit	myelin transcription factor 1 like
chr16_-_970954 Show fit	9.78	ENST00000543238.5 ENST00000262301.16	LMF1 Ensembl NCBI GeneCards UniProt Show fit	lipase maturation factor 1
chr6_+_109095110 Show fit	9.77	ENST00000521277.5 ENST00000407272.5 ENST00000519286.5	CEP57L1 Ensembl NCBI GeneCards UniProt Show fit	centrosomal protein 57 like 1
chr14_+_74019341 Show fit	9.70	ENST00000394009.5 ENST00000464394.5	BBOF1 Ensembl NCBI GeneCards UniProt Show fit	basal body orientation factor 1
chr5_-_11588842 Show fit	9.65	ENST00000503622.5	CTNND2 Ensembl NCBI GeneCards UniProt Show fit	catenin delta 2
chr4_+_70721953 Show fit	9.64	ENST00000381006.8 ENST00000226328.8	RUFY3 Ensembl NCBI GeneCards UniProt Show fit	RUN and FYVE domain containing 3
chr11_+_131370478 Show fit	9.62	ENST00000374791.7 ENST00000683400.1 ENST00000436745.5	NTM Ensembl NCBI GeneCards UniProt Show fit	neurotrimin
chr1_+_145927105 Show fit	9.61	ENST00000437797.5 ENST00000601726.3 ENST00000599626.5 ENST00000599147.5 ENST00000595494.5 ENST00000595518.5 ENST00000597144.5 ENST00000599469.5 ENST00000598354.5 ENST00000598103.5 ENST00000600340.5 ENST00000630257.2 ENST00000625258.1	LIX1L-AS1 Ensembl NCBI GeneCards UniProt Show fit ENSG00000280778.1 Ensembl NCBI GeneCards UniProt Show fit	LIX1L antisense RNA 1 novel protein, lncRNA-POLR3GL readthrough
chr19_+_35292145 Show fit	9.56	ENST00000595791.5 ENST00000597035.5 ENST00000537831.2 ENST00000392213.8	MAG Ensembl NCBI GeneCards UniProt Show fit	myelin associated glycoprotein
chr15_+_74995520 Show fit	9.55	ENST00000562327.5 ENST00000568018.5 ENST00000425597.8 ENST00000562212.5 ENST00000567920.5 ENST00000566872.5 ENST00000361900.10	SCAMP5 Ensembl NCBI GeneCards UniProt Show fit	secretory carrier membrane protein 5
chr6_-_29633171 Show fit	9.50	ENST00000377034.9	GABBR1 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type B receptor subunit 1
chr2_-_127107259 Show fit	9.50	ENST00000409400.1 ENST00000357970.7 ENST00000393040.7 ENST00000348750.8 ENST00000259238.8 ENST00000346226.7 ENST00000393041.7 ENST00000351659.7 ENST00000352848.7	BIN1 Ensembl NCBI GeneCards UniProt Show fit	bridging integrator 1
chr6_-_29633056 Show fit	9.50	ENST00000377016.8	GABBR1 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type B receptor subunit 1
chr2_+_79512993 Show fit	9.48	ENST00000496558.5 ENST00000451966.5 ENST00000402739.9 ENST00000629316.2	CTNNA2 Ensembl NCBI GeneCards UniProt Show fit	catenin alpha 2
chr7_-_135510074 Show fit	9.46	ENST00000428680.6 ENST00000423368.6 ENST00000451834.5 ENST00000361528.8 ENST00000541284.5 ENST00000315544.6	CNOT4 Ensembl NCBI GeneCards UniProt Show fit	CCR4-NOT transcription complex subunit 4
chrX_-_139642889 Show fit	9.44	ENST00000370576.9	MCF2 Ensembl NCBI GeneCards UniProt Show fit	MCF.2 cell line derived transforming sequence
chr12_-_7091873 Show fit	9.44	ENST00000538050.5 ENST00000536053.6	C1R Ensembl NCBI GeneCards UniProt Show fit	complement C1r
chr7_-_22193824 Show fit	9.44	ENST00000401957.6	RAPGEF5 Ensembl NCBI GeneCards UniProt Show fit	Rap guanine nucleotide exchange factor 5
chr10_-_72088972 Show fit	9.43	ENST00000317376.8 ENST00000412663.5	SPOCK2 Ensembl NCBI GeneCards UniProt Show fit	SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
chr6_+_125919210 Show fit	9.39	ENST00000438495.6	NCOA7 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor coactivator 7
chr20_+_33235987 Show fit	9.38	ENST00000375422.6 ENST00000375413.8 ENST00000354297.9	BPIFA1 Ensembl NCBI GeneCards UniProt Show fit	BPI fold containing family A member 1
chr7_-_137343752 Show fit	9.36	ENST00000393083.2	PTN Ensembl NCBI GeneCards UniProt Show fit	pleiotrophin
chr12_-_14885845 Show fit	9.34	ENST00000539261.6 ENST00000228938.5	MGP Ensembl NCBI GeneCards UniProt Show fit	matrix Gla protein

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
14.7	250.5	GO:0007021	tubulin complex assembly(GO:0007021)
12.7	38.1	GO:1903288	positive regulation of potassium ion import(GO:1903288)
11.7	35.1	GO:1990168	protein K33-linked deubiquitination(GO:1990168)
11.7	46.7	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
9.3	27.8	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
8.9	26.8	GO:1900920	regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
7.9	23.7	GO:0060988	lipid tube assembly(GO:0060988)
6.8	20.5	GO:0060221	retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
6.5	110.5	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
6.5	45.5	GO:0070560	protein secretion by platelet(GO:0070560)
6.3	57.0	GO:0016198	axon choice point recognition(GO:0016198)
5.8	17.4	GO:0042704	uterine wall breakdown(GO:0042704) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
5.3	21.2	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
5.0	15.1	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
4.9	24.6	GO:0071494	cellular response to UV-C(GO:0071494)
4.6	13.9	GO:0072023	thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
4.5	18.0	GO:0097676	histone H3-K36 dimethylation(GO:0097676)
4.4	13.3	GO:0014813	skeletal muscle satellite cell commitment(GO:0014813)
4.2	21.1	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
4.0	20.2	GO:1902847	regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
4.0	15.8	GO:0007499	ectoderm and mesoderm interaction(GO:0007499)
4.0	11.9	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
3.9	15.6	GO:0019074	viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
3.9	11.7	GO:0021913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
3.8	79.0	GO:0032291	central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
3.6	14.5	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
3.5	10.4	GO:0060875	subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
3.5	3.5	GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
3.2	16.1	GO:1903906	plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
3.1	62.5	GO:2000821	regulation of grooming behavior(GO:2000821)
3.1	12.4	GO:0032972	regulation of muscle filament sliding speed(GO:0032972)
3.1	9.2	GO:0070634	transepithelial ammonium transport(GO:0070634)
3.1	6.2	GO:1903281	positive regulation of calcium:sodium antiporter activity(GO:1903281)
3.0	12.1	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
3.0	9.1	GO:1901731	positive regulation of platelet aggregation(GO:1901731)
3.0	9.0	GO:0048691	modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
3.0	20.8	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
3.0	47.3	GO:0070445	oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
2.8	36.8	GO:1902548	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
2.8	39.2	GO:0070050	neuron cellular homeostasis(GO:0070050)
2.8	22.2	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
2.8	11.1	GO:0051866	general adaptation syndrome(GO:0051866)
2.8	30.5	GO:0036376	sodium ion export from cell(GO:0036376)
2.8	19.4	GO:1904098	regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
2.8	19.3	GO:1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
2.7	10.8	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
2.7	8.1	GO:0072275	metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
2.5	22.3	GO:0033578	protein glycosylation in Golgi(GO:0033578)
2.4	7.1	GO:0001983	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
2.3	9.4	GO:1900229	biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
2.3	6.9	GO:0051365	cellular response to potassium ion starvation(GO:0051365)
2.3	6.9	GO:1901877	regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
2.3	6.8	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
2.3	6.8	GO:0071139	resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
2.2	8.9	GO:0015910	peroxisomal long-chain fatty acid import(GO:0015910)
2.2	19.8	GO:0099566	regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
2.2	26.3	GO:0051612	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
2.2	4.4	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
2.2	8.7	GO:0099558	maintenance of synapse structure(GO:0099558)
2.2	6.5	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
2.2	6.5	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
2.1	10.7	GO:0010159	specification of organ position(GO:0010159)
2.1	16.4	GO:0003185	primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
2.0	30.7	GO:0006600	creatine metabolic process(GO:0006600)
2.0	6.0	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
1.9	5.8	GO:1901624	negative regulation of lymphocyte chemotaxis(GO:1901624)
1.9	28.2	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.8	11.1	GO:0032489	regulation of Cdc42 protein signal transduction(GO:0032489)
1.8	49.4	GO:0007158	neuron cell-cell adhesion(GO:0007158)
1.8	5.5	GO:0098528	skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
1.8	20.0	GO:0008354	germ cell migration(GO:0008354)
1.8	7.3	GO:0097167	circadian regulation of translation(GO:0097167)
1.8	12.5	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
1.8	12.5	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
1.8	12.5	GO:0051388	positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.8	8.9	GO:0035645	posterior midgut development(GO:0007497) enteric smooth muscle cell differentiation(GO:0035645)
1.8	12.4	GO:0007042	lysosomal lumen acidification(GO:0007042)
1.8	12.3	GO:0045007	depurination(GO:0045007)
1.7	5.2	GO:0070346	positive regulation of fat cell proliferation(GO:0070346)
1.7	5.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
1.7	10.2	GO:0001826	inner cell mass cell differentiation(GO:0001826)
1.7	5.1	GO:2001025	cellular response to mycotoxin(GO:0036146) response to cyclosporin A(GO:1905237) positive regulation of response to drug(GO:2001025)
1.7	6.7	GO:2000638	regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
1.7	15.0	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
1.7	3.3	GO:0002582	positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
1.7	14.9	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
1.6	6.6	GO:0018199	peptidyl-glutamine modification(GO:0018199)
1.6	48.6	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
1.5	3.0	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
1.5	20.7	GO:0021942	radial glia guided migration of Purkinje cell(GO:0021942)
1.5	4.4	GO:1901994	meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
1.4	18.8	GO:0070327	thyroid hormone transport(GO:0070327)
1.4	10.0	GO:0006102	isocitrate metabolic process(GO:0006102)
1.4	8.5	GO:0051012	microtubule sliding(GO:0051012)
1.4	7.1	GO:1903392	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
1.4	4.2	GO:0051097	negative regulation of helicase activity(GO:0051097)
1.4	7.1	GO:0007197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
1.4	8.4	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
1.4	61.6	GO:0008038	neuron recognition(GO:0008038)
1.4	13.9	GO:0045329	carnitine biosynthetic process(GO:0045329)
1.4	4.2	GO:0070845	misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
1.4	1.4	GO:0010726	positive regulation of hydrogen peroxide metabolic process(GO:0010726)
1.3	5.4	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.3	13.5	GO:1990504	dense core granule exocytosis(GO:1990504)
1.3	5.3	GO:1904428	negative regulation of tubulin deacetylation(GO:1904428)
1.3	5.3	GO:0060708	spongiotrophoblast differentiation(GO:0060708)
1.3	5.2	GO:1900827	maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
1.3	20.6	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
1.3	34.0	GO:0034204	lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
1.3	6.3	GO:0098912	membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
1.2	3.7	GO:0071812	regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
1.2	34.9	GO:0010669	epithelial structure maintenance(GO:0010669)
1.2	2.5	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
1.2	5.0	GO:0030432	peristalsis(GO:0030432)
1.2	42.2	GO:0035235	ionotropic glutamate receptor signaling pathway(GO:0035235)
1.2	9.7	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.2	3.6	GO:2000053	regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
1.2	11.8	GO:0014052	regulation of gamma-aminobutyric acid secretion(GO:0014052)
1.2	2.3	GO:0060018	astrocyte fate commitment(GO:0060018)
1.2	4.6	GO:0060029	convergent extension involved in organogenesis(GO:0060029)
1.1	9.0	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
1.1	3.4	GO:0019878	lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878) L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
1.1	7.9	GO:0052055	modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
1.1	6.7	GO:0015793	glycerol transport(GO:0015793)
1.1	16.6	GO:0014029	neural crest formation(GO:0014029)
1.1	3.3	GO:2001302	lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
1.1	29.3	GO:0071420	cellular response to histamine(GO:0071420)
1.1	8.7	GO:0061709	reticulophagy(GO:0061709)
1.1	1.1	GO:0002368	B cell cytokine production(GO:0002368)
1.1	5.3	GO:0070092	regulation of glucagon secretion(GO:0070092)
1.1	5.3	GO:0048105	establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
1.0	11.5	GO:0047484	regulation of response to osmotic stress(GO:0047484)
1.0	2.1	GO:0048850	hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
1.0	3.1	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
1.0	19.6	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
1.0	3.0	GO:0033082	extrathymic T cell differentiation(GO:0033078) regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
1.0	7.1	GO:0033591	response to L-ascorbic acid(GO:0033591)
1.0	28.8	GO:0090140	regulation of mitochondrial fission(GO:0090140)
1.0	10.9	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
1.0	4.0	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
1.0	155.9	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.0	15.6	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
1.0	5.8	GO:0070131	positive regulation of mitochondrial translation(GO:0070131)
1.0	13.6	GO:0006776	vitamin A metabolic process(GO:0006776)
1.0	2.9	GO:0048664	neuron fate determination(GO:0048664)
1.0	4.8	GO:0030259	lipid glycosylation(GO:0030259)
0.9	13.2	GO:0021692	cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.9	10.3	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.9	3.7	GO:0021759	globus pallidus development(GO:0021759)
0.9	2.8	GO:1990451	cellular stress response to acidic pH(GO:1990451)
0.9	22.4	GO:0007628	adult walking behavior(GO:0007628)
0.9	1.8	GO:0035962	response to interleukin-13(GO:0035962)
0.9	16.5	GO:0006071	glycerol metabolic process(GO:0006071)
0.9	7.8	GO:0043249	erythrocyte maturation(GO:0043249)
0.9	10.2	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.8	2.5	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.8	5.0	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
0.8	56.5	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.8	4.1	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.8	4.1	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.8	14.6	GO:0097186	amelogenesis(GO:0097186)
0.8	2.4	GO:0002019	regulation of renal output by angiotensin(GO:0002019)
0.8	3.2	GO:0018879	biphenyl metabolic process(GO:0018879)
0.8	18.2	GO:0070262	peptidyl-serine dephosphorylation(GO:0070262)
0.8	7.9	GO:0030322	stabilization of membrane potential(GO:0030322)
0.8	5.5	GO:0086016	AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.8	6.2	GO:0080182	histone H3-K4 trimethylation(GO:0080182)
0.8	15.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.8	8.4	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.8	8.3	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.7	2.2	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.7	16.1	GO:0006704	glucocorticoid biosynthetic process(GO:0006704)
0.7	3.6	GO:1904075	trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.7	15.2	GO:0060736	prostate gland growth(GO:0060736)
0.7	8.7	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
0.7	24.3	GO:0007019	microtubule depolymerization(GO:0007019)
0.7	2.8	GO:2000173	negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.7	2.8	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.7	8.3	GO:0097151	positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.7	18.3	GO:0007214	gamma-aminobutyric acid signaling pathway(GO:0007214)
0.7	6.8	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.7	14.8	GO:0035640	exploration behavior(GO:0035640)
0.7	3.4	GO:0061762	CAMKK-AMPK signaling cascade(GO:0061762)
0.7	2.0	GO:0033364	mast cell secretory granule organization(GO:0033364)
0.7	2.0	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
0.7	4.0	GO:0014807	regulation of somitogenesis(GO:0014807)
0.6	7.1	GO:2000795	trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.6	1.9	GO:0035425	autocrine signaling(GO:0035425)
0.6	1.9	GO:0045900	negative regulation of translational elongation(GO:0045900) positive regulation of mRNA polyadenylation(GO:1900365)
0.6	17.9	GO:0046688	response to copper ion(GO:0046688)
0.6	5.7	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.6	3.8	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.6	6.2	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.6	1.2	GO:2000525	regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.6	1.9	GO:0021965	spinal cord ventral commissure morphogenesis(GO:0021965)
0.6	2.5	GO:0071725	toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.6	8.0	GO:1990035	calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.6	1.2	GO:0002876	regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
0.6	6.0	GO:0019317	fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.6	16.2	GO:0048665	neuron fate specification(GO:0048665)
0.6	2.4	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
0.6	2.4	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.6	6.0	GO:0016576	histone dephosphorylation(GO:0016576)
0.6	15.4	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.6	6.1	GO:0071313	cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.5	4.4	GO:0006572	tyrosine catabolic process(GO:0006572)
0.5	1.6	GO:0060332	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.5	4.9	GO:0070315	G1 to G0 transition involved in cell differentiation(GO:0070315)
0.5	12.8	GO:0030517	negative regulation of axon extension(GO:0030517)
0.5	2.1	GO:0001692	histamine metabolic process(GO:0001692)
0.5	1.5	GO:0097210	response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.5	0.5	GO:2000538	positive regulation of thymocyte migration(GO:2000412) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.5	1.5	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.5	9.6	GO:0045956	positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.5	13.5	GO:0001502	cartilage condensation(GO:0001502)
0.5	2.5	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.5	8.4	GO:0003322	pancreatic A cell development(GO:0003322)
0.5	1.4	GO:0060671	epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.5	7.7	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.5	22.0	GO:0043551	regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.5	0.9	GO:2000977	regulation of forebrain neuron differentiation(GO:2000977)
0.5	3.7	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.5	4.2	GO:0048625	myoblast fate commitment(GO:0048625)
0.5	10.9	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.5	1.8	GO:0036058	filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.4	1.3	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.4	29.0	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.4	9.6	GO:0050771	negative regulation of axonogenesis(GO:0050771)
0.4	1.8	GO:0002879	acute inflammatory response to non-antigenic stimulus(GO:0002525) regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.4	1.7	GO:0002933	lipid hydroxylation(GO:0002933)
0.4	6.7	GO:0040032	post-embryonic body morphogenesis(GO:0040032)
0.4	7.1	GO:0035563	positive regulation of chromatin binding(GO:0035563)
0.4	2.5	GO:0016098	monoterpenoid metabolic process(GO:0016098)
0.4	1.2	GO:0097498	endothelial tube lumen extension(GO:0097498)
0.4	0.8	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
0.4	6.9	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.4	6.4	GO:0005513	detection of calcium ion(GO:0005513)
0.4	12.8	GO:0010107	potassium ion import(GO:0010107)
0.4	3.2	GO:0001573	ganglioside metabolic process(GO:0001573)
0.4	6.3	GO:0001976	neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.4	2.0	GO:0042048	olfactory behavior(GO:0042048)
0.4	22.5	GO:0006458	'de novo' protein folding(GO:0006458)
0.4	4.6	GO:2000178	negative regulation of neural precursor cell proliferation(GO:2000178)
0.4	11.2	GO:0045063	T-helper 1 cell differentiation(GO:0045063)
0.4	3.4	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.4	3.4	GO:0086024	adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.4	5.3	GO:0060044	negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.4	3.0	GO:0070235	regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.4	10.5	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.4	6.8	GO:0009812	flavonoid metabolic process(GO:0009812)
0.4	4.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.4	0.7	GO:0050720	interleukin-1 beta biosynthetic process(GO:0050720)
0.4	1.1	GO:1904352	positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.4	1.4	GO:0002371	dendritic cell cytokine production(GO:0002371)
0.4	4.7	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.4	3.9	GO:0070571	negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.3	6.3	GO:0045662	negative regulation of myoblast differentiation(GO:0045662)
0.3	16.8	GO:0006509	membrane protein ectodomain proteolysis(GO:0006509)
0.3	2.0	GO:0072592	oxygen metabolic process(GO:0072592)
0.3	4.3	GO:0044804	nucleophagy(GO:0044804)
0.3	1.0	GO:1902724	mineralocorticoid receptor signaling pathway(GO:0031959) regulation of growth hormone receptor signaling pathway(GO:0060398) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.3	5.4	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.3	2.5	GO:0045793	positive regulation of cell size(GO:0045793)
0.3	11.7	GO:0097120	receptor localization to synapse(GO:0097120)
0.3	5.4	GO:0006744	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.3	2.8	GO:0034285	response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.3	3.4	GO:0008090	retrograde axonal transport(GO:0008090)
0.3	14.2	GO:0003197	endocardial cushion development(GO:0003197)
0.3	3.7	GO:0015074	DNA integration(GO:0015074)
0.3	6.1	GO:0030826	regulation of cGMP biosynthetic process(GO:0030826)
0.3	0.9	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.3	2.1	GO:0098700	neurotransmitter loading into synaptic vesicle(GO:0098700)
0.3	5.0	GO:0003416	endochondral bone growth(GO:0003416)
0.3	9.4	GO:0030516	regulation of axon extension(GO:0030516)
0.3	0.6	GO:0048865	stem cell fate commitment(GO:0048865)
0.3	18.4	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.3	1.4	GO:0042738	exogenous drug catabolic process(GO:0042738)
0.3	5.4	GO:0036150	phosphatidylserine acyl-chain remodeling(GO:0036150)
0.3	0.8	GO:0051549	positive regulation of keratinocyte migration(GO:0051549)
0.3	12.6	GO:0010761	fibroblast migration(GO:0010761)
0.3	3.6	GO:0030202	heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.3	3.3	GO:0000050	urea cycle(GO:0000050)
0.3	7.7	GO:0014898	muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.3	1.4	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.3	3.8	GO:0010818	T cell chemotaxis(GO:0010818)
0.3	2.1	GO:0006203	dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.3	0.5	GO:0061357	positive regulation of Wnt protein secretion(GO:0061357)
0.3	0.3	GO:0036022	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.3	3.3	GO:0050919	negative chemotaxis(GO:0050919)
0.3	3.1	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.3	16.3	GO:0051865	protein autoubiquitination(GO:0051865)
0.3	2.8	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
0.3	3.0	GO:0001778	plasma membrane repair(GO:0001778)
0.3	0.5	GO:0060527	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.3	2.0	GO:0045905	translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2	6.7	GO:0032012	regulation of ARF protein signal transduction(GO:0032012)
0.2	1.7	GO:0046886	positive regulation of hormone biosynthetic process(GO:0046886)
0.2	12.8	GO:0002088	lens development in camera-type eye(GO:0002088)
0.2	1.6	GO:0042791	5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.2	8.7	GO:0035082	axoneme assembly(GO:0035082)
0.2	0.5	GO:0072709	cellular response to sorbitol(GO:0072709)
0.2	2.2	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.2	0.4	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.2	4.6	GO:1903846	positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.2	29.5	GO:0046718	viral entry into host cell(GO:0046718)
0.2	6.3	GO:0022400	regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.2	1.1	GO:0060012	synaptic transmission, glycinergic(GO:0060012)
0.2	6.8	GO:0086010	membrane depolarization during action potential(GO:0086010)
0.2	1.3	GO:0070942	neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.2	0.9	GO:2000382	positive regulation of mesoderm development(GO:2000382)
0.2	0.8	GO:1904672	regulation of somatic stem cell population maintenance(GO:1904672)
0.2	1.1	GO:0060155	platelet dense granule organization(GO:0060155)
0.2	0.7	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.2	6.6	GO:0043001	Golgi to plasma membrane protein transport(GO:0043001)
0.2	0.5	GO:0099550	trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.2	2.2	GO:0006700	C21-steroid hormone biosynthetic process(GO:0006700)
0.2	12.5	GO:0010977	negative regulation of neuron projection development(GO:0010977)
0.2	0.5	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.2	2.9	GO:0044458	motile cilium assembly(GO:0044458)
0.2	0.3	GO:0021800	cerebral cortex tangential migration(GO:0021800) cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2	1.8	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.2	8.5	GO:0060997	dendritic spine morphogenesis(GO:0060997)
0.2	16.5	GO:0005977	glycogen metabolic process(GO:0005977)
0.2	3.3	GO:0035728	response to hepatocyte growth factor(GO:0035728)
0.2	16.0	GO:0090630	activation of GTPase activity(GO:0090630)
0.2	1.0	GO:0001946	lymphangiogenesis(GO:0001946)
0.2	3.2	GO:0016048	detection of temperature stimulus(GO:0016048)
0.2	2.2	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.2	2.2	GO:0006020	inositol metabolic process(GO:0006020)
0.2	3.3	GO:0006884	cell volume homeostasis(GO:0006884)
0.2	6.4	GO:0016486	peptide hormone processing(GO:0016486)
0.2	4.2	GO:0072661	protein targeting to plasma membrane(GO:0072661)
0.2	2.7	GO:1900038	negative regulation of cellular response to hypoxia(GO:1900038)
0.2	11.7	GO:0090502	RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1	0.6	GO:0045144	meiotic sister chromatid segregation(GO:0045144)
0.1	7.2	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.1	2.5	GO:0003334	keratinocyte development(GO:0003334)
0.1	0.7	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1	6.1	GO:1901385	regulation of voltage-gated calcium channel activity(GO:1901385)
0.1	6.4	GO:0021954	central nervous system neuron development(GO:0021954)
0.1	0.9	GO:0051775	response to redox state(GO:0051775)
0.1	1.6	GO:0021670	lateral ventricle development(GO:0021670)
0.1	2.6	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1	0.8	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1	5.1	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.1	3.6	GO:0018149	peptide cross-linking(GO:0018149)
0.1	3.8	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.1	1.6	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.1	2.6	GO:0033119	negative regulation of RNA splicing(GO:0033119)
0.1	0.4	GO:1902462	transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1	1.4	GO:0042753	positive regulation of circadian rhythm(GO:0042753)
0.1	1.6	GO:0042268	regulation of cytolysis(GO:0042268)
0.1	2.6	GO:0035036	sperm-egg recognition(GO:0035036)
0.1	1.7	GO:0006590	thyroid hormone generation(GO:0006590)
0.1	0.3	GO:0038043	interleukin-5-mediated signaling pathway(GO:0038043)
0.1	2.6	GO:0014072	response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.1	3.6	GO:0042982	amyloid precursor protein metabolic process(GO:0042982)
0.1	2.0	GO:0007340	acrosome reaction(GO:0007340)
0.1	1.5	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.1	0.4	GO:0043314	negative regulation of neutrophil degranulation(GO:0043314)
0.1	0.7	GO:1904321	response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1	0.4	GO:0098911	regulation of ventricular cardiac muscle cell action potential(GO:0098911)
0.1	5.6	GO:0015701	bicarbonate transport(GO:0015701)
0.1	1.5	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1	0.4	GO:0001766	membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1	3.5	GO:0007274	neuromuscular synaptic transmission(GO:0007274)
0.1	12.9	GO:0035023	regulation of Rho protein signal transduction(GO:0035023)
0.1	1.2	GO:0015985	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1	0.9	GO:0002347	response to tumor cell(GO:0002347)
0.1	1.0	GO:0035873	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1	0.7	GO:0033015	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1	4.2	GO:0016266	O-glycan processing(GO:0016266)
0.1	2.1	GO:0035338	long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1	0.3	GO:0070459	prolactin secretion(GO:0070459)
0.1	1.0	GO:0035855	megakaryocyte development(GO:0035855)
0.1	3.8	GO:0006826	iron ion transport(GO:0006826)
0.1	3.7	GO:1902476	chloride transmembrane transport(GO:1902476)
0.1	27.2	GO:0043547	positive regulation of GTPase activity(GO:0043547)
0.1	0.6	GO:0071542	dopaminergic neuron differentiation(GO:0071542)
0.1	1.6	GO:0060711	labyrinthine layer development(GO:0060711)
0.1	5.0	GO:1903955	positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0	1.0	GO:0060261	positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0	1.7	GO:0070098	chemokine-mediated signaling pathway(GO:0070098)
0.0	2.2	GO:0030010	establishment of cell polarity(GO:0030010)
0.0	2.1	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.1	GO:1900121	negative regulation of receptor binding(GO:1900121)
0.0	1.9	GO:0006805	xenobiotic metabolic process(GO:0006805)
0.0	0.3	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.2	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.7	GO:0021510	spinal cord development(GO:0021510)
0.0	0.2	GO:0030238	male sex determination(GO:0030238)
0.0	0.2	GO:0070734	histone H3-K27 methylation(GO:0070734)
0.0	0.9	GO:0030449	regulation of complement activation(GO:0030449)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
17.4	279.0	GO:0097512	cardiac myofibril(GO:0097512)
12.0	36.0	GO:0098843	postsynaptic endocytic zone(GO:0098843)
11.8	58.8	GO:0072534	perineuronal net(GO:0072534)
9.5	57.0	GO:0032584	growth cone membrane(GO:0032584)
7.9	23.7	GO:0060987	lipid tube(GO:0060987)
6.2	18.7	GO:0070931	Golgi-associated vesicle lumen(GO:0070931)
5.5	99.2	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
4.8	19.0	GO:0038039	G-protein coupled receptor heterodimeric complex(GO:0038039)
4.4	17.7	GO:0038038	G-protein coupled receptor homodimeric complex(GO:0038038)
4.0	11.9	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
2.7	21.8	GO:0045179	apical cortex(GO:0045179)
2.7	16.1	GO:0070545	PeBoW complex(GO:0070545)
2.6	65.5	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
2.6	36.4	GO:0098839	postsynaptic density membrane(GO:0098839)
2.5	32.5	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
2.1	6.3	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
1.8	14.5	GO:0097442	CA3 pyramidal cell dendrite(GO:0097442)
1.8	10.7	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
1.7	3.5	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
1.7	8.3	GO:0036128	CatSper complex(GO:0036128)
1.6	21.0	GO:0035749	myelin sheath adaxonal region(GO:0035749)
1.5	7.7	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.5	6.2	GO:0090533	cation-transporting ATPase complex(GO:0090533)
1.4	7.1	GO:0005826	actomyosin contractile ring(GO:0005826)
1.4	34.7	GO:0001518	voltage-gated sodium channel complex(GO:0001518)
1.4	4.1	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
1.3	16.2	GO:0043083	synaptic cleft(GO:0043083)
1.3	25.6	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
1.3	20.2	GO:0042583	chromaffin granule(GO:0042583)
1.2	6.9	GO:0035253	ciliary rootlet(GO:0035253)
1.1	4.6	GO:0034678	integrin alpha8-beta1 complex(GO:0034678)
1.1	6.8	GO:0033061	DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
1.1	11.2	GO:0005614	interstitial matrix(GO:0005614)
1.1	11.1	GO:0070852	cell body fiber(GO:0070852)
1.1	3.2	GO:0034686	integrin alphav-beta8 complex(GO:0034686)
1.0	9.4	GO:0032133	chromosome passenger complex(GO:0032133)
1.0	8.3	GO:0061700	GATOR2 complex(GO:0061700)
1.0	235.0	GO:0030426	growth cone(GO:0030426)
1.0	8.2	GO:0005579	membrane attack complex(GO:0005579)
1.0	6.0	GO:0005594	collagen type IX trimer(GO:0005594)
1.0	6.9	GO:0030893	meiotic cohesin complex(GO:0030893)
1.0	5.8	GO:0032593	insulin-responsive compartment(GO:0032593)
1.0	6.7	GO:1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.9	5.5	GO:1990769	proximal neuron projection(GO:1990769)
0.9	11.1	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.9	9.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.9	4.4	GO:0072687	meiotic spindle(GO:0072687)
0.9	12.9	GO:0030478	actin cap(GO:0030478)
0.8	3.1	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.8	12.4	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.8	6.0	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.7	5.2	GO:0031143	pseudopodium(GO:0031143)
0.7	7.3	GO:0033018	sarcoplasmic reticulum lumen(GO:0033018)
0.7	120.1	GO:0031225	anchored component of membrane(GO:0031225)
0.7	28.6	GO:1902710	GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.7	3.4	GO:0031673	H zone(GO:0031673)
0.6	2.8	GO:0071438	invadopodium membrane(GO:0071438)
0.5	7.1	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.5	9.8	GO:0005922	connexon complex(GO:0005922)
0.5	5.3	GO:0030427	site of polarized growth(GO:0030427)
0.5	2.7	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.5	32.6	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.5	22.1	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.5	5.1	GO:0046581	intercellular canaliculus(GO:0046581)
0.5	10.0	GO:0000974	Prp19 complex(GO:0000974)
0.5	4.2	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.4	18.2	GO:0016592	mediator complex(GO:0016592)
0.4	2.2	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.4	3.9	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.4	37.2	GO:0042734	presynaptic membrane(GO:0042734)
0.4	35.7	GO:0043195	terminal bouton(GO:0043195)
0.4	4.5	GO:0032281	AMPA glutamate receptor complex(GO:0032281)
0.4	4.0	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.4	9.5	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.4	7.5	GO:0032982	myosin filament(GO:0032982)
0.4	6.1	GO:0035102	PRC1 complex(GO:0035102)
0.4	15.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.4	1.8	GO:0005921	gap junction(GO:0005921)
0.4	1.8	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.4	4.7	GO:0031618	chromocenter(GO:0010369) nuclear pericentric heterochromatin(GO:0031618)
0.4	25.9	GO:0055038	recycling endosome membrane(GO:0055038)
0.4	4.2	GO:0070369	beta-catenin-TCF7L2 complex(GO:0070369)
0.3	6.3	GO:0042622	photoreceptor outer segment membrane(GO:0042622)
0.3	4.5	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.3	4.1	GO:0005577	fibrinogen complex(GO:0005577)
0.3	6.1	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.3	3.0	GO:0031209	SCAR complex(GO:0031209)
0.3	22.7	GO:0005796	Golgi lumen(GO:0005796)
0.3	1.0	GO:0005674	transcription factor TFIIF complex(GO:0005674)
0.3	19.2	GO:0035577	azurophil granule membrane(GO:0035577)
0.3	1.8	GO:0016342	catenin complex(GO:0016342)
0.3	0.6	GO:0000939	condensed chromosome inner kinetochore(GO:0000939)
0.3	37.2	GO:0043204	perikaryon(GO:0043204)
0.3	11.1	GO:0005697	telomerase holoenzyme complex(GO:0005697)
0.3	7.1	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.3	3.1	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3	2.5	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.2	6.4	GO:0097542	ciliary tip(GO:0097542)
0.2	8.2	GO:0035861	site of double-strand break(GO:0035861)
0.2	4.3	GO:0034045	pre-autophagosomal structure membrane(GO:0034045)
0.2	1.6	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.2	0.7	GO:0016939	kinesin II complex(GO:0016939)
0.2	15.0	GO:0005776	autophagosome(GO:0005776)
0.2	2.7	GO:0097486	multivesicular body lumen(GO:0097486)
0.2	2.2	GO:0043190	ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.2	4.3	GO:0101003	ficolin-1-rich granule membrane(GO:0101003)
0.2	25.3	GO:0005923	bicellular tight junction(GO:0005923)
0.2	2.4	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.2	3.7	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2	47.2	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.2	2.5	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.2	3.6	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.2	64.1	GO:0005578	proteinaceous extracellular matrix(GO:0005578)
0.2	1.2	GO:0060077	inhibitory synapse(GO:0060077)
0.2	5.5	GO:0009925	basal plasma membrane(GO:0009925)
0.2	5.8	GO:0016328	lateral plasma membrane(GO:0016328)
0.2	4.7	GO:0005779	integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2	8.3	GO:0030315	T-tubule(GO:0030315)
0.2	8.2	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2	5.2	GO:0090568	nuclear transcriptional repressor complex(GO:0090568)
0.2	3.6	GO:0030673	axolemma(GO:0030673)
0.1	3.7	GO:0002080	acrosomal membrane(GO:0002080)
0.1	7.1	GO:0005902	microvillus(GO:0005902)
0.1	5.9	GO:0005811	lipid particle(GO:0005811)
0.1	4.0	GO:0034451	centriolar satellite(GO:0034451)
0.1	1.0	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1	5.4	GO:0001533	cornified envelope(GO:0001533)
0.1	0.8	GO:0070160	occluding junction(GO:0070160)
0.1	20.7	GO:0098793	presynapse(GO:0098793)
0.1	1.4	GO:0000242	pericentriolar material(GO:0000242)
0.1	1.5	GO:0043296	apical junction complex(GO:0043296)
0.1	1.4	GO:0030056	hemidesmosome(GO:0030056)
0.1	10.1	GO:0045211	postsynaptic membrane(GO:0045211)
0.1	6.8	GO:0005834	heterotrimeric G-protein complex(GO:0005834)
0.1	6.0	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.1	0.8	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.1	5.1	GO:0016528	sarcoplasm(GO:0016528)
0.1	1.1	GO:0042629	mast cell granule(GO:0042629)
0.1	1.1	GO:0031083	BLOC-1 complex(GO:0031083)
0.1	8.7	GO:0034705	voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1	0.7	GO:0035686	sperm fibrous sheath(GO:0035686)
0.1	5.9	GO:0009897	external side of plasma membrane(GO:0009897)
0.1	10.3	GO:0030424	axon(GO:0030424)
0.1	5.9	GO:0036064	ciliary basal body(GO:0036064)
0.1	0.5	GO:0036021	endolysosome lumen(GO:0036021)
0.1	2.1	GO:0008305	integrin complex(GO:0008305)
0.1	4.7	GO:0005913	cell-cell adherens junction(GO:0005913)
0.1	2.8	GO:0044438	microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.1	11.0	GO:0005802	trans-Golgi network(GO:0005802)
0.1	2.9	GO:0005905	clathrin-coated pit(GO:0005905)
0.1	1.7	GO:0034707	chloride channel complex(GO:0034707)
0.1	16.1	GO:0044297	cell body(GO:0044297)
0.0	3.5	GO:0035097	histone methyltransferase complex(GO:0035097)
0.0	0.9	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	1.0	GO:0031519	PcG protein complex(GO:0031519)
0.0	1.5	GO:0005876	spindle microtubule(GO:0005876)
0.0	2.6	GO:0098794	postsynapse(GO:0098794)
0.0	0.5	GO:0001673	male germ cell nucleus(GO:0001673)
0.0	5.6	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	33.9	GO:0005789	endoplasmic reticulum membrane(GO:0005789)
0.0	4.6	GO:0005741	mitochondrial outer membrane(GO:0005741)
0.0	0.2	GO:0097550	transcriptional preinitiation complex(GO:0097550)
0.0	4.9	GO:0043005	neuron projection(GO:0043005)
0.0	0.4	GO:0031904	endosome lumen(GO:0031904)
0.0	2.0	GO:0005875	microtubule associated complex(GO:0005875)
0.0	1.2	GO:0000794	condensed nuclear chromosome(GO:0000794)
0.0	44.1	GO:0016021	integral component of membrane(GO:0016021)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.6	257.5	GO:0005212	structural constituent of eye lens(GO:0005212)
7.9	23.8	GO:0030350	iron-responsive element binding(GO:0030350)
6.3	56.8	GO:0035727	lysophosphatidic acid binding(GO:0035727)
6.3	81.6	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
6.1	30.3	GO:0004522	ribonuclease A activity(GO:0004522)
6.0	24.2	GO:0097001	ceramide binding(GO:0097001)
5.8	23.1	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
5.4	48.9	GO:0030274	LIM domain binding(GO:0030274)
5.3	42.7	GO:0004971	AMPA glutamate receptor activity(GO:0004971)
4.8	14.3	GO:0003845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
4.8	19.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
4.7	18.7	GO:0008798	beta-aspartyl-peptidase activity(GO:0008798)
4.6	13.9	GO:0008336	gamma-butyrobetaine dioxygenase activity(GO:0008336)
4.6	27.6	GO:1904315	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
4.2	12.5	GO:0017129	triglyceride binding(GO:0017129)
4.1	32.4	GO:0031811	G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
4.0	11.9	GO:0004157	dihydropyrimidinase activity(GO:0004157)
4.0	11.9	GO:0030305	heparanase activity(GO:0030305)
4.0	47.4	GO:0019911	structural constituent of myelin sheath(GO:0019911)
3.9	11.8	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
3.9	31.2	GO:0004111	creatine kinase activity(GO:0004111)
3.5	17.4	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
3.4	13.7	GO:0016639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
3.4	27.0	GO:0004865	protein serine/threonine phosphatase inhibitor activity(GO:0004865)
3.3	20.0	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
3.3	65.0	GO:0097109	neuroligin family protein binding(GO:0097109)
3.2	15.9	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
3.1	18.7	GO:0030172	troponin C binding(GO:0030172)
3.1	12.3	GO:0004741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
3.1	12.3	GO:0032408	MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
2.9	17.7	GO:0099583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
2.8	8.4	GO:0036505	prosaposin receptor activity(GO:0036505)
2.8	19.4	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
2.7	8.1	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
2.6	18.4	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
2.6	20.8	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
2.6	7.7	GO:0003863	alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
2.6	15.4	GO:0000285	1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
2.5	20.2	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
2.5	10.0	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
2.2	13.2	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
2.1	19.2	GO:0004565	beta-galactosidase activity(GO:0004565)
2.1	8.3	GO:0070728	leucine binding(GO:0070728)
2.1	64.4	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
2.0	18.4	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
2.0	28.2	GO:0015501	glutamate:sodium symporter activity(GO:0015501)
2.0	18.0	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
2.0	25.6	GO:0086056	voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
2.0	5.9	GO:0015275	stretch-activated, cation-selective, calcium channel activity(GO:0015275)
1.9	5.8	GO:0008169	C-methyltransferase activity(GO:0008169)
1.9	5.8	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
1.9	21.0	GO:0033691	sialic acid binding(GO:0033691)
1.8	9.0	GO:0043183	vascular endothelial growth factor receptor 1 binding(GO:0043183)
1.8	7.1	GO:0031716	calcitonin receptor binding(GO:0031716)
1.8	14.2	GO:0060002	plus-end directed microfilament motor activity(GO:0060002)
1.7	17.4	GO:0016721	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.7	5.2	GO:0005502	11-cis retinal binding(GO:0005502)
1.7	35.2	GO:0001011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.7	6.7	GO:0015254	glycerol channel activity(GO:0015254)
1.6	4.9	GO:0004382	guanosine-diphosphatase activity(GO:0004382)
1.6	22.6	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
1.6	11.1	GO:0001515	opioid peptide activity(GO:0001515)
1.5	10.8	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
1.5	10.7	GO:0001849	complement component C1q binding(GO:0001849)
1.4	39.1	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
1.4	10.0	GO:0016167	glial cell-derived neurotrophic factor receptor activity(GO:0016167)
1.4	7.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
1.4	2.8	GO:0004948	calcitonin receptor activity(GO:0004948)
1.4	5.5	GO:0031728	CCR3 chemokine receptor binding(GO:0031728)
1.4	4.1	GO:0061609	fructose-1-phosphate aldolase activity(GO:0061609)
1.3	25.0	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
1.3	9.2	GO:0070891	lipoteichoic acid binding(GO:0070891)
1.3	15.6	GO:0004075	biotin carboxylase activity(GO:0004075)
1.3	5.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.3	45.7	GO:0071837	HMG box domain binding(GO:0071837)
1.2	14.6	GO:0008430	selenium binding(GO:0008430)
1.2	15.8	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
1.2	21.9	GO:0043560	insulin receptor substrate binding(GO:0043560)
1.2	10.4	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
1.2	24.2	GO:0005112	Notch binding(GO:0005112)
1.1	12.5	GO:0001968	fibronectin binding(GO:0001968)
1.1	10.2	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
1.1	11.1	GO:0030215	semaphorin receptor binding(GO:0030215)
1.1	24.4	GO:0051787	misfolded protein binding(GO:0051787)
1.1	3.3	GO:0047977	hepoxilin-epoxide hydrolase activity(GO:0047977)
1.1	10.8	GO:0030911	TPR domain binding(GO:0030911)
1.1	8.4	GO:0005000	vasopressin receptor activity(GO:0005000)
1.0	9.4	GO:0035174	histone serine kinase activity(GO:0035174)
1.0	5.2	GO:0051373	FATZ binding(GO:0051373)
1.0	11.2	GO:0031995	insulin-like growth factor II binding(GO:0031995)
1.0	15.1	GO:0031432	titin binding(GO:0031432)
1.0	11.1	GO:0003964	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
1.0	17.9	GO:0038191	neuropilin binding(GO:0038191)
1.0	6.8	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.9	2.8	GO:0030171	voltage-gated proton channel activity(GO:0030171)
0.9	3.6	GO:0050119	N-acetylglucosamine deacetylase activity(GO:0050119)
0.9	6.3	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.9	18.6	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.9	9.6	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.9	4.3	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.9	15.4	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.8	6.7	GO:0050816	phosphothreonine binding(GO:0050816)
0.8	9.1	GO:0015250	water channel activity(GO:0015250)
0.8	3.2	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.8	7.9	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.8	2.4	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.8	6.2	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.8	6.9	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.7	3.7	GO:0048763	calcium-induced calcium release activity(GO:0048763)
0.7	6.3	GO:0043855	intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.7	4.1	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.7	5.4	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.7	5.4	GO:0030249	guanylate cyclase regulator activity(GO:0030249)
0.7	6.0	GO:0046920	alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.7	6.0	GO:0030020	extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.7	2.7	GO:0043515	kinetochore binding(GO:0043515)
0.7	7.2	GO:0038132	neuregulin binding(GO:0038132)
0.7	9.8	GO:0005243	gap junction channel activity(GO:0005243)
0.6	4.5	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.6	8.4	GO:0016918	retinal binding(GO:0016918) retinol binding(GO:0019841)
0.6	5.0	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.6	3.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.6	1.9	GO:0005042	netrin receptor activity(GO:0005042)
0.6	35.0	GO:0030507	spectrin binding(GO:0030507)
0.6	14.0	GO:0031005	filamin binding(GO:0031005)
0.6	16.4	GO:0030506	ankyrin binding(GO:0030506)
0.6	13.9	GO:1905030	voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.6	4.2	GO:0005499	vitamin D binding(GO:0005499)
0.6	5.4	GO:0047144	2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.6	1.8	GO:0004507	steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.6	2.4	GO:0005111	type 2 fibroblast growth factor receptor binding(GO:0005111)
0.6	12.2	GO:0002162	dystroglycan binding(GO:0002162)
0.6	1.7	GO:0004874	aryl hydrocarbon receptor activity(GO:0004874)
0.6	3.4	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.6	10.6	GO:0008066	glutamate receptor activity(GO:0008066)
0.6	43.6	GO:0050840	extracellular matrix binding(GO:0050840)
0.5	8.7	GO:0044548	S100 protein binding(GO:0044548)
0.5	2.1	GO:0008832	dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793) guanyl deoxyribonucleotide binding(GO:0032560) dGTP binding(GO:0032567)
0.5	0.5	GO:0034875	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.5	3.6	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.5	3.1	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.5	2.0	GO:0071532	ankyrin repeat binding(GO:0071532)
0.5	2.4	GO:0031711	tripeptidyl-peptidase activity(GO:0008240) peptidyl-dipeptidase activity(GO:0008241) bradykinin receptor binding(GO:0031711) metallodipeptidase activity(GO:0070573)
0.5	0.9	GO:0050692	DBD domain binding(GO:0050692)
0.5	5.7	GO:0004875	complement receptor activity(GO:0004875)
0.5	11.2	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.5	4.1	GO:0022851	GABA-gated chloride ion channel activity(GO:0022851)
0.5	6.8	GO:0005344	oxygen transporter activity(GO:0005344)
0.4	1.3	GO:0035248	alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.4	2.2	GO:0033857	diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.4	39.8	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.4	4.9	GO:0039706	co-receptor binding(GO:0039706)
0.4	26.0	GO:0015485	cholesterol binding(GO:0015485)
0.4	5.1	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.4	7.1	GO:0001222	transcription corepressor binding(GO:0001222)
0.4	48.3	GO:0001618	virus receptor activity(GO:0001618)
0.4	4.0	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.4	10.1	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.4	2.2	GO:0017127	cholesterol transporter activity(GO:0017127)
0.4	2.6	GO:1990932	5.8S rRNA binding(GO:1990932)
0.4	17.5	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.4	4.4	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.4	1.4	GO:0004925	prolactin receptor activity(GO:0004925)
0.4	30.3	GO:0004722	protein serine/threonine phosphatase activity(GO:0004722)
0.4	1.4	GO:0032934	sterol binding(GO:0032934)
0.4	4.3	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.3	1.7	GO:0004447	iodide peroxidase activity(GO:0004447)
0.3	4.8	GO:0008376	acetylgalactosaminyltransferase activity(GO:0008376)
0.3	5.7	GO:0016805	dipeptidase activity(GO:0016805)
0.3	18.8	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.3	1.3	GO:0005148	prolactin receptor binding(GO:0005148)
0.3	5.1	GO:0044213	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.3	27.8	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.3	4.7	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.3	4.7	GO:0005229	intracellular calcium activated chloride channel activity(GO:0005229)
0.3	5.6	GO:0048156	tau protein binding(GO:0048156)
0.3	18.5	GO:0030331	estrogen receptor binding(GO:0030331)
0.3	16.6	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.3	2.4	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.3	3.3	GO:0043176	amine binding(GO:0043176) serotonin binding(GO:0051378)
0.3	24.1	GO:0004712	protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.3	5.6	GO:0008510	sodium:bicarbonate symporter activity(GO:0008510)
0.3	7.9	GO:0000146	microfilament motor activity(GO:0000146)
0.3	2.8	GO:0005237	inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.3	13.3	GO:0017080	sodium channel regulator activity(GO:0017080)
0.3	4.2	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.3	4.2	GO:0019215	intermediate filament binding(GO:0019215)
0.3	30.5	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3	202.9	GO:0005509	calcium ion binding(GO:0005509)
0.3	12.8	GO:0016859	cis-trans isomerase activity(GO:0016859)
0.2	2.0	GO:0051430	corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2	0.7	GO:0008267	poly-glutamine tract binding(GO:0008267)
0.2	6.3	GO:0001972	retinoic acid binding(GO:0001972)
0.2	1.8	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.2	25.8	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.2	6.7	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.2	5.6	GO:0005109	frizzled binding(GO:0005109)
0.2	19.0	GO:0008013	beta-catenin binding(GO:0008013)
0.2	0.4	GO:0005497	androgen binding(GO:0005497)
0.2	2.5	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.2	6.7	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2	3.4	GO:0008320	protein transmembrane transporter activity(GO:0008320)
0.2	5.1	GO:0016712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.2	7.7	GO:0005227	calcium activated cation channel activity(GO:0005227)
0.2	7.7	GO:0001102	RNA polymerase II activating transcription factor binding(GO:0001102)
0.2	8.8	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.2	2.6	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2	6.9	GO:0030145	manganese ion binding(GO:0030145)
0.2	3.0	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.2	1.5	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2	2.7	GO:0015467	G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2	11.1	GO:0004620	phospholipase activity(GO:0004620)
0.1	0.6	GO:0005169	neurotrophin TRKB receptor binding(GO:0005169)
0.1	5.3	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.1	0.7	GO:0019862	IgA binding(GO:0019862)
0.1	46.0	GO:0005096	GTPase activator activity(GO:0005096)
0.1	1.0	GO:0019992	diacylglycerol binding(GO:0019992)
0.1	2.8	GO:0005388	calcium-transporting ATPase activity(GO:0005388)
0.1	3.4	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1	0.4	GO:0043682	copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.1	4.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.1	5.2	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1	6.9	GO:0019894	kinesin binding(GO:0019894)
0.1	2.6	GO:0050321	tau-protein kinase activity(GO:0050321)
0.1	23.8	GO:0003729	mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1	1.0	GO:0000990	transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1	1.5	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.1	7.5	GO:0002039	p53 binding(GO:0002039)
0.1	0.3	GO:0004914	interleukin-5 receptor activity(GO:0004914)
0.1	1.2	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1	3.0	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1	1.7	GO:0016004	phospholipase activator activity(GO:0016004)
0.1	5.6	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1	0.8	GO:0004996	thyroid-stimulating hormone receptor activity(GO:0004996)
0.1	3.0	GO:0048487	beta-tubulin binding(GO:0048487)
0.1	0.5	GO:0017147	Wnt-protein binding(GO:0017147)
0.1	0.4	GO:0051525	NFAT protein binding(GO:0051525)
0.1	2.1	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.1	1.0	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.1	2.0	GO:0003746	translation elongation factor activity(GO:0003746)
0.1	8.6	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.1	0.3	GO:0031013	troponin I binding(GO:0031013)
0.1	1.5	GO:0043425	bHLH transcription factor binding(GO:0043425)
0.1	2.4	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1	5.5	GO:0051087	chaperone binding(GO:0051087)
0.1	14.0	GO:0004252	serine-type endopeptidase activity(GO:0004252)
0.1	0.6	GO:0015172	L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.1	1.4	GO:0071889	14-3-3 protein binding(GO:0071889)
0.1	11.8	GO:0008017	microtubule binding(GO:0008017)
0.1	1.4	GO:0019956	chemokine binding(GO:0019956)
0.0	21.3	GO:0004930	G-protein coupled receptor activity(GO:0004930)
0.0	3.9	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.0	0.5	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	1.0	GO:0046961	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	2.9	GO:0004725	protein tyrosine phosphatase activity(GO:0004725)
0.0	1.8	GO:0030170	pyridoxal phosphate binding(GO:0030170)
0.0	0.9	GO:0003774	motor activity(GO:0003774)
0.0	0.6	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.9	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004)
0.0	1.8	GO:0005200	structural constituent of cytoskeleton(GO:0005200)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.6	108.9	PID NCADHERIN PATHWAY	N-cadherin signaling events
1.1	6.8	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
1.0	50.0	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.9	40.6	ST GA12 PATHWAY	G alpha 12 Pathway
0.8	6.6	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.7	31.3	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.6	16.8	PID SYNDECAN 3 PATHWAY	Syndecan-3-mediated signaling events
0.6	10.2	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.6	40.5	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.5	8.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.4	29.0	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.4	28.0	PID MAPK TRK PATHWAY	Trk receptor signaling mediated by the MAPK pathway
0.4	5.9	PID NECTIN PATHWAY	Nectin adhesion pathway
0.4	5.1	PID IL27 PATHWAY	IL27-mediated signaling events
0.4	4.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3	47.3	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.3	20.0	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.3	5.0	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3	10.6	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.3	5.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3	62.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.3	15.2	PID ILK PATHWAY	Integrin-linked kinase signaling
0.3	7.4	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.3	15.1	PID ATR PATHWAY	ATR signaling pathway
0.3	3.6	PID IGF1 PATHWAY	IGF1 pathway
0.3	8.5	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.3	16.0	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.2	16.5	PID LKB1 PATHWAY	LKB1 signaling events
0.2	30.7	PID BETA CATENIN NUC PATHWAY	Regulation of nuclear beta catenin signaling and target gene transcription
0.2	19.8	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.2	9.0	PID FGF PATHWAY	FGF signaling pathway
0.2	3.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2	6.8	PID SHP2 PATHWAY	SHP2 signaling
0.2	2.8	PID RAC1 PATHWAY	RAC1 signaling pathway
0.2	14.2	PID P75 NTR PATHWAY	p75(NTR)-mediated signaling
0.2	4.0	ST GAQ PATHWAY	G alpha q Pathway
0.2	6.3	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.2	6.3	PID RHODOPSIN PATHWAY	Visual signal transduction: Rods
0.2	11.5	PID AURORA B PATHWAY	Aurora B signaling
0.2	8.4	SIG CHEMOTAXIS	Genes related to chemotaxis
0.2	2.9	PID PI3K PLC TRK PATHWAY	Trk receptor signaling mediated by PI3K and PLC-gamma
0.2	4.4	PID REELIN PATHWAY	Reelin signaling pathway
0.2	7.1	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.2	10.6	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.2	2.1	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.2	3.7	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.2	11.2	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.1	6.0	PID IL23 PATHWAY	IL23-mediated signaling events
0.1	3.1	PID ARF 3PATHWAY	Arf1 pathway
0.1	1.7	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1	3.0	PID MYC PATHWAY	C-MYC pathway
0.1	2.8	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.1	3.4	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.1	2.3	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.1	12.9	PID P53 DOWNSTREAM PATHWAY	Direct p53 effectors
0.1	25.9	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	1.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	12.5	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1	3.8	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.1	0.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	1.5	PID FANCONI PATHWAY	Fanconi anemia pathway
0.1	0.3	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.8	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.4	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	11.4	NABA MATRISOME ASSOCIATED	Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0	1.0	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.4	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.4	PID ENDOTHELIN PATHWAY	Endothelins
0.0	0.4	PID HES HEY PATHWAY	Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
2.2	118.9	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
2.1	42.9	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.5	38.3	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
1.3	6.5	REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES	Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
1.3	27.8	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
1.1	7.9	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
1.1	21.1	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
1.0	42.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.9	25.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.9	34.7	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.9	31.4	REACTOME RECYCLING PATHWAY OF L1	Genes involved in Recycling pathway of L1
0.9	35.9	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.9	52.1	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.8	18.3	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions
0.7	5.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.6	7.7	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.6	15.8	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.6	14.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.6	12.3	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.6	10.2	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.6	18.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.6	2.8	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.6	24.8	REACTOME AMYLOIDS	Genes involved in Amyloids
0.5	13.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5	9.8	REACTOME GAP JUNCTION ASSEMBLY	Genes involved in Gap junction assembly
0.5	11.9	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.5	7.8	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.5	18.6	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.5	6.7	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.5	8.7	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.5	1.5	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.5	9.0	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.5	4.0	REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION	Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.5	9.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.4	15.4	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.4	4.7	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.4	30.6	REACTOME NCAM1 INTERACTIONS	Genes involved in NCAM1 interactions
0.4	19.9	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.4	2.9	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.4	13.7	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.4	5.0	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.4	8.3	REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.4	22.4	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.3	67.3	REACTOME PEPTIDE LIGAND BINDING RECEPTORS	Genes involved in Peptide ligand-binding receptors
0.3	5.7	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.3	47.2	REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES	Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.3	6.7	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.3	4.1	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.3	12.8	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.3	7.3	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.3	11.2	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.3	3.9	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.3	5.0	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.3	3.6	REACTOME SIGNALLING TO P38 VIA RIT AND RIN	Genes involved in Signalling to p38 via RIT and RIN
0.3	4.8	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.2	10.3	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.2	10.8	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.2	3.5	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.2	23.4	REACTOME INTEGRIN CELL SURFACE INTERACTIONS	Genes involved in Integrin cell surface interactions
0.2	4.2	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.2	8.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2	3.0	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.2	13.7	REACTOME STRIATED MUSCLE CONTRACTION	Genes involved in Striated Muscle Contraction
0.2	21.3	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.2	1.4	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.2	4.0	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.2	3.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.2	6.6	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.2	2.5	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.2	1.6	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.2	2.4	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2	1.1	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.2	6.0	REACTOME G ALPHA S SIGNALLING EVENTS	Genes involved in G alpha (s) signalling events
0.2	11.8	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.1	4.6	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1	4.2	REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION	Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1	3.9	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.1	3.0	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.1	1.0	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.1	4.3	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.1	7.3	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.1	4.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.1	1.7	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.1	5.2	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.1	13.1	REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES	Genes involved in Transmission across Chemical Synapses
0.1	0.7	REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE	Genes involved in Nitric oxide stimulates guanylate cyclase
0.1	15.0	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.1	2.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	1.7	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1	2.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.1	4.6	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1	1.9	REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION	Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1	1.6	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	1.3	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.7	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.5	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	2.1	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.0	0.8	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.2	REACTOME OPSINS	Genes involved in Opsins
0.0	0.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo

Results for EZH2

Z-value: 8.85

Motif logo

Transcription factors associated with EZH2

Activity-expression correlation:

Activity profile of EZH2 motif

Sorted Z-values of EZH2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EZH2

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: