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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for EZH2

Z-value: 8.85

Motif logo

Transcription factors associated with EZH2

Gene Symbol Gene ID Gene Info
ENSG00000106462.12 EZH2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EZH2hg38_v1_chr7_-_148883474_148883509-0.647.7e-27Click!

Activity profile of EZH2 motif

Sorted Z-values of EZH2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EZH2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_-_111910888 81.90 ENST00000525823.1
ENST00000528961.6
crystallin alpha B
chr11_-_111910790 75.23 ENST00000533280.6
crystallin alpha B
chr11_-_111910830 73.21 ENST00000526167.5
ENST00000651650.1
crystallin alpha B
chr3_+_115623502 57.00 ENST00000305124.11
ENST00000393780.3
growth associated protein 43
chr17_+_7650916 38.08 ENST00000250111.9
ATPase Na+/K+ transporting subunit beta 2
chr7_+_140404034 35.88 ENST00000537763.6
RAB19, member RAS oncogene family
chr6_-_73452124 35.65 ENST00000680833.1
cyclic GMP-AMP synthase
chrX_+_70062457 35.08 ENST00000338352.3
OTU deubiquitinase 6A
chr3_-_195583931 32.80 ENST00000343267.8
ENST00000421243.5
ENST00000453131.1
apolipoprotein D
chr4_-_16898561 32.71 ENST00000515064.5
ENST00000441778.6
LIM domain binding 2
chr16_+_7304219 32.51 ENST00000675562.1
RNA binding fox-1 homolog 1
chr11_-_133532493 31.02 ENST00000524381.6
opioid binding protein/cell adhesion molecule like
chr14_-_21022817 28.46 ENST00000554104.5
NDRG family member 2
chr13_-_67230377 27.60 ENST00000544246.5
ENST00000377861.4
protocadherin 9
chr7_+_121873317 27.53 ENST00000651863.1
ENST00000652298.1
ENST00000449182.1
protein tyrosine phosphatase receptor type Z1
chr11_-_111911759 27.50 ENST00000650687.2
crystallin alpha B
chr8_+_22059198 27.13 ENST00000523266.5
ENST00000519907.5
dematin actin binding protein
chr13_-_67230313 26.93 ENST00000377865.7
protocadherin 9
chr1_+_160127672 26.84 ENST00000447527.1
ATPase Na+/K+ transporting subunit alpha 2
chrX_-_13817346 26.30 ENST00000356942.9
glycoprotein M6B
chr8_+_79611036 26.24 ENST00000220876.12
ENST00000518111.5
stathmin 2
chr16_+_7303245 26.09 ENST00000674626.1
RNA binding fox-1 homolog 1
chr5_-_160685379 25.56 ENST00000642502.1
ATPase phospholipid transporting 10B (putative)
chr19_-_36032799 24.19 ENST00000592017.5
ENST00000360535.9
CAP-Gly domain containing linker protein 3
chr3_-_58587033 23.83 ENST00000447756.2
family with sequence similarity 107 member A
chr14_-_21022494 23.79 ENST00000449431.6
NDRG family member 2
chrX_+_103776831 23.56 ENST00000621218.5
ENST00000619236.1
proteolipid protein 1
chrX_+_103776493 23.48 ENST00000433491.5
ENST00000612423.4
ENST00000443502.5
proteolipid protein 1
chr2_-_50347789 22.90 ENST00000628364.2
neurexin 1
chr5_-_147081428 22.23 ENST00000394413.7
protein phosphatase 2 regulatory subunit Bbeta
chr15_+_43593054 21.25 ENST00000453782.5
ENST00000300283.10
ENST00000437924.5
creatine kinase, mitochondrial 1B
chr7_+_121873478 21.24 ENST00000651320.1
protein tyrosine phosphatase receptor type Z1
chr12_-_44876294 21.21 ENST00000429094.7
ENST00000551601.5
ENST00000549027.5
ENST00000452445.6
neural EGFL like 2
chr15_+_43517590 21.20 ENST00000300231.6
microtubule associated protein 1A
chr4_+_157220654 21.12 ENST00000393815.6
glutamate ionotropic receptor AMPA type subunit 2
chr8_+_79611727 20.51 ENST00000518491.1
stathmin 2
chr14_-_21023144 20.36 ENST00000554531.5
NDRG family member 2
chr14_-_21022432 20.34 ENST00000557633.5
NDRG family member 2
chr8_-_27611424 20.21 ENST00000405140.7
clusterin
chr1_-_56579555 20.00 ENST00000371250.4
phospholipid phosphatase 3
chr5_+_141359970 19.92 ENST00000522605.2
ENST00000622527.1
protocadherin gamma subfamily B, 2
chr1_-_163202835 19.48 ENST00000527988.1
ENST00000531476.1
ENST00000530507.5
ENST00000313961.10
regulator of G protein signaling 5
chr15_+_43594027 19.04 ENST00000453733.5
ENST00000441322.6
ENST00000627381.1
creatine kinase, mitochondrial 1B
chr8_-_18808837 18.93 ENST00000286485.12
pleckstrin and Sec7 domain containing 3
chr17_-_7219813 18.88 ENST00000399510.8
ENST00000648172.8
discs large MAGUK scaffold protein 4
chr6_-_166627244 18.71 ENST00000265678.9
ribosomal protein S6 kinase A2
chr12_-_50167292 18.42 ENST00000547800.2
ENST00000317551.12
ENST00000422340.6
ceramide synthase 5
chr15_+_43693859 18.35 ENST00000413453.7
ENST00000415044.3
ENST00000626814.1
creatine kinase, mitochondrial 1A
chr8_+_22059169 18.34 ENST00000358242.5
dematin actin binding protein
chr6_-_6006878 18.15 ENST00000244766.7
neuritin 1
chr12_-_44875647 17.98 ENST00000395487.6
neural EGFL like 2
chr14_-_44961889 17.92 ENST00000579157.1
ENST00000396128.9
ENST00000556500.1
kelch like family member 28
chr21_+_25639251 17.81 ENST00000480456.6
junctional adhesion molecule 2
chr14_-_21022258 17.53 ENST00000556366.5
NDRG family member 2
chr4_+_24795560 17.43 ENST00000382120.4
superoxide dismutase 3
chr11_-_113875555 17.42 ENST00000003302.8
ENST00000545540.5
ubiquitin specific peptidase 28
chr14_-_75981986 17.35 ENST00000238682.8
transforming growth factor beta 3
chr6_-_73452253 17.00 ENST00000370318.5
ENST00000370315.4
cyclic GMP-AMP synthase
chr7_-_22193728 16.81 ENST00000620335.4
Rap guanine nucleotide exchange factor 5
chr12_-_91182784 16.72 ENST00000547568.6
ENST00000052754.10
ENST00000552962.5
decorin
chr12_+_6821797 16.60 ENST00000311268.8
ENST00000382315.7
G protein-coupled receptor 162
chr14_-_20802402 16.44 ENST00000412779.2
ribonuclease A family member 1, pancreatic
chr4_-_16898619 16.22 ENST00000502640.5
ENST00000304523.10
ENST00000506732.1
LIM domain binding 2
chr9_+_121299793 16.08 ENST00000373818.8
gelsolin
chr15_+_78438279 15.80 ENST00000560440.5
iron responsive element binding protein 2
chr12_-_91182652 15.77 ENST00000552145.5
ENST00000546745.5
decorin
chr11_-_66958366 15.60 ENST00000651036.1
ENST00000652125.1
ENST00000531614.6
ENST00000524491.6
ENST00000529047.6
ENST00000393960.7
ENST00000393958.7
ENST00000528403.6
ENST00000651854.1
pyruvate carboxylase
chr19_-_48646155 15.44 ENST00000084798.9
carbonic anhydrase 11
chr6_-_109440504 15.37 ENST00000520723.5
ENST00000518648.1
ENST00000417394.6
ENST00000521072.7
peptidylprolyl isomerase like 6
chr17_-_48590231 15.22 ENST00000476342.1
ENST00000460160.5
ENST00000498678.6
ENST00000472863.5
homeobox B3
chr1_-_230714112 15.11 ENST00000681514.1
ENST00000366667.6
ENST00000680041.1
angiotensinogen
chr19_-_41994079 15.00 ENST00000602133.5
ATPase Na+/K+ transporting subunit alpha 3
chr4_+_157220691 14.92 ENST00000509417.5
ENST00000645636.1
ENST00000296526.12
ENST00000264426.14
glutamate ionotropic receptor AMPA type subunit 2
chr12_+_6821646 14.89 ENST00000428545.6
G protein-coupled receptor 162
chr1_-_177164673 14.80 ENST00000424564.2
ENST00000361833.7
astrotactin 1
chr16_+_31074390 14.54 ENST00000300850.5
ENST00000564189.1
ENST00000428260.1
zinc finger protein 646
chr2_+_209424039 14.51 ENST00000682079.1
ENST00000199940.10
microtubule associated protein 2
chr1_+_209686173 14.28 ENST00000615289.4
ENST00000367028.6
ENST00000261465.5
hydroxysteroid 11-beta dehydrogenase 1
chr2_-_68157470 14.20 ENST00000406245.6
ENST00000409164.1
ENST00000295121.11
WD repeat domain 92
chr2_-_127107144 14.19 ENST00000316724.10
bridging integrator 1
chr5_+_161848536 14.10 ENST00000519621.2
ENST00000636573.1
gamma-aminobutyric acid type A receptor subunit alpha1
chr3_+_147409357 14.02 ENST00000282928.5
Zic family member 1
chr5_-_147081462 14.00 ENST00000508267.5
ENST00000504198.5
protein phosphatase 2 regulatory subunit Bbeta
chr14_-_20802836 13.85 ENST00000397967.5
ENST00000555698.5
ENST00000397970.4
ENST00000340900.3
ribonuclease A family member 1, pancreatic
chr12_-_54588636 13.82 ENST00000257905.13
protein phosphatase 1 regulatory inhibitor subunit 1A
chr19_+_35140022 13.78 ENST00000588081.5
ENST00000589121.1
FXYD domain containing ion transport regulator 1
chr16_-_21278282 13.74 ENST00000572914.2
crystallin mu
chr18_-_55510753 13.50 ENST00000543082.5
transcription factor 4
chr5_+_161848314 13.49 ENST00000437025.6
gamma-aminobutyric acid type A receptor subunit alpha1
chr7_+_129611680 13.45 ENST00000393232.6
ENST00000454688.5
ENST00000223190.8
ENST00000311967.6
nuclear respiratory factor 1
chr6_+_43576119 13.30 ENST00000372236.9
DNA polymerase eta
chr14_+_92323154 13.24 ENST00000532405.6
ENST00000676001.1
ENST00000531433.5
solute carrier family 24 member 4
chr12_-_54588516 13.21 ENST00000547431.5
protein phosphatase 1 regulatory inhibitor subunit 1A
chr5_-_20575850 13.21 ENST00000507958.5
cadherin 18
chr11_-_66729184 13.19 ENST00000533211.6
ENST00000309996.7
spectrin beta, non-erythrocytic 2
chr21_+_25639272 13.08 ENST00000400532.5
ENST00000312957.9
junctional adhesion molecule 2
chr8_-_126558461 12.93 ENST00000304916.4
LRAT domain containing 2
chr6_-_166862502 12.83 ENST00000510118.5
ENST00000503859.5
ENST00000506565.1
ribosomal protein S6 kinase A2
chr15_+_43692886 12.82 ENST00000434505.5
ENST00000411750.5
creatine kinase, mitochondrial 1A
chr1_+_151070740 12.82 ENST00000368918.8
GA binding protein transcription factor subunit beta 2
chr14_+_44962177 12.77 ENST00000361462.7
ENST00000361577.7
TOG array regulator of axonemal microtubules 1
chr16_-_29899532 12.77 ENST00000308713.9
ENST00000617533.5
seizure related 6 homolog like 2
chr2_-_218010202 12.76 ENST00000646520.1
tensin 1
chr7_-_100428657 12.72 ENST00000360951.8
ENST00000398027.6
ENST00000684423.1
ENST00000472716.1
zinc finger CW-type and PWWP domain containing 1
chr11_-_123654939 12.72 ENST00000657191.1
sodium voltage-gated channel beta subunit 3
chr6_+_31982057 12.69 ENST00000428956.7
ENST00000498271.1
complement C4A (Rodgers blood group)
chr8_-_27258414 12.66 ENST00000523048.5
stathmin 4
chr16_-_970847 12.54 ENST00000568897.5
lipase maturation factor 1
chr8_+_19939246 12.52 ENST00000650287.1
lipoprotein lipase
chr19_+_42076129 12.52 ENST00000359044.5
zinc finger protein 574
chr7_-_122886706 12.46 ENST00000313070.11
ENST00000334010.11
ENST00000615869.4
calcium dependent secretion activator 2
chr17_+_28357638 12.42 ENST00000292114.8
ENST00000591482.1
transmembrane protein 199
novel transcript readthrough between TMEM199 and SARM1
chr1_-_201373229 12.35 ENST00000367317.8
ENST00000360372.8
ENST00000236918.11
ENST00000367315.6
ENST00000658476.1
troponin T2, cardiac type
chr6_+_19837362 12.32 ENST00000378700.8
inhibitor of DNA binding 4, HLH protein
chr16_+_66880503 12.26 ENST00000568869.1
ENST00000311765.4
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr6_+_29656993 12.18 ENST00000376888.6
myelin oligodendrocyte glycoprotein
chr4_-_76023489 12.17 ENST00000306602.3
C-X-C motif chemokine ligand 10
chr16_-_31074193 12.11 ENST00000300849.5
zinc finger protein 668
chr11_-_117295485 12.07 ENST00000680971.1
beta-secretase 1
chr2_-_69643703 12.00 ENST00000406297.7
ENST00000409085.9
AP2 associated kinase 1
chr1_-_72282457 11.94 ENST00000357731.10
neuronal growth regulator 1
chr8_+_26577843 11.93 ENST00000311151.9
dihydropyrimidinase like 2
chr14_+_74084947 11.92 ENST00000674221.1
ENST00000554938.2
lin-52 DREAM MuvB core complex component
chr1_+_156619406 11.86 ENST00000255039.6
ENST00000456112.1
hyaluronan and proteoglycan link protein 2
chr5_+_93583212 11.81 ENST00000327111.8
nuclear receptor subfamily 2 group F member 1
chr1_-_149917826 11.80 ENST00000369145.1
ENST00000369146.8
synaptic vesicle glycoprotein 2A
chr7_-_101200912 11.79 ENST00000440203.6
ENST00000379423.3
ENST00000223114.9
monoacylglycerol O-acyltransferase 3
chr6_+_29657085 11.66 ENST00000376917.8
ENST00000376894.8
myelin oligodendrocyte glycoprotein
chr3_+_29281049 11.64 ENST00000383767.7
RNA binding motif single stranded interacting protein 3
chr2_+_104854104 11.54 ENST00000361360.4
POU class 3 homeobox 3
chr22_-_50085414 11.53 ENST00000311597.10
modulator of VRAC current 1
chr1_+_2073462 11.45 ENST00000400921.6
protein kinase C zeta
chr19_+_35292125 11.42 ENST00000600291.5
ENST00000361922.8
myelin associated glycoprotein
chr6_+_43576205 11.31 ENST00000372226.1
ENST00000443535.1
DNA polymerase eta
chr8_-_27258386 11.30 ENST00000350889.8
ENST00000519997.5
ENST00000519614.5
ENST00000522908.1
ENST00000265770.11
stathmin 4
chr3_-_112641128 11.21 ENST00000206423.8
coiled-coil domain containing 80
chr7_-_137343688 11.14 ENST00000348225.7
pleiotrophin
chr11_+_27040725 11.11 ENST00000529202.5
ENST00000263182.8
gamma-butyrobetaine hydroxylase 1
chr14_-_53153098 11.11 ENST00000612692.4
ENST00000395606.5
DDHD domain containing 1
chr5_+_36608146 11.11 ENST00000381918.4
ENST00000513646.1
solute carrier family 1 member 3
chr8_-_56446572 11.11 ENST00000518974.5
ENST00000451791.7
ENST00000523051.5
ENST00000518770.1
proenkephalin
chr4_+_155666827 11.10 ENST00000511507.5
ENST00000506455.6
guanylate cyclase 1 soluble subunit alpha 1
chr18_-_43115625 11.09 ENST00000590910.1
ENST00000326695.10
ENST00000589109.5
Ras like without CAAX 2
chr5_-_134371004 11.04 ENST00000521755.1
ENST00000523054.5
ENST00000518409.1
cyclin dependent kinase like 3
novel transcript
chr7_+_100539188 10.94 ENST00000300176.9
ArfGAP with FG repeats 2
chr15_+_43791842 10.92 ENST00000674451.1
ENST00000630046.2
small EDRK-rich factor 2
chr5_-_74641419 10.92 ENST00000618628.4
ENST00000510316.5
ENST00000508331.1
ectodermal-neural cortex 1
chr2_-_69643615 10.86 ENST00000409068.5
AP2 associated kinase 1
chr11_-_72674394 10.84 ENST00000418754.6
ENST00000334456.10
ENST00000542969.2
phosphodiesterase 2A
chr5_+_141350081 10.84 ENST00000523390.2
ENST00000611598.1
protocadherin gamma subfamily B, 1
chr18_+_74597850 10.79 ENST00000582337.5
ENST00000299687.10
zinc finger protein 407
chr6_+_29657120 10.76 ENST00000396704.7
ENST00000416766.6
ENST00000483013.5
ENST00000490427.5
ENST00000376891.8
ENST00000376898.7
ENST00000396701.6
ENST00000494692.5
ENST00000431798.6
myelin oligodendrocyte glycoprotein
chr17_+_18315273 10.74 ENST00000406438.5
SMCR8-C9orf72 complex subunit
chr20_-_49278416 10.66 ENST00000371754.8
zinc finger NFX1-type containing 1
chr10_+_17809337 10.54 ENST00000569591.3
mannose receptor C-type 1
chr12_-_55707865 10.51 ENST00000347027.10
ENST00000257879.11
ENST00000553804.6
integrin subunit alpha 7
chr2_+_80305105 10.49 ENST00000541047.5
catenin alpha 2
chr19_+_57231014 10.45 ENST00000302804.12
aurora kinase C
chr5_-_116536458 10.40 ENST00000510263.5
semaphorin 6A
chrX_-_139642835 10.38 ENST00000536274.5
MCF.2 cell line derived transforming sequence
chr1_+_50108856 10.38 ENST00000650764.1
ENST00000494555.2
ENST00000371824.7
ENST00000371823.8
ENST00000652693.1
ELAV like RNA binding protein 4
chr1_+_2073986 10.32 ENST00000461106.6
protein kinase C zeta
chr11_-_123654581 10.31 ENST00000392770.6
ENST00000530277.5
ENST00000299333.8
sodium voltage-gated channel beta subunit 3
chr12_+_101594849 10.26 ENST00000547405.5
ENST00000452455.6
ENST00000392934.7
ENST00000547509.5
ENST00000361685.6
ENST00000549145.5
ENST00000361466.7
ENST00000553190.5
ENST00000545503.6
ENST00000536007.5
ENST00000541119.5
ENST00000551300.5
ENST00000550270.1
myosin binding protein C1
chr6_+_125919296 10.22 ENST00000444128.2
nuclear receptor coactivator 7
chr20_-_54070520 10.17 ENST00000371435.6
ENST00000395961.7
brain enriched myelin associated protein 1
chr17_+_7484357 10.04 ENST00000674977.2
RNA polymerase II subunit A
chr10_+_18340699 10.04 ENST00000377329.10
calcium voltage-gated channel auxiliary subunit beta 2
chrX_-_153794356 10.03 ENST00000427365.6
ENST00000444450.5
ENST00000217901.10
ENST00000370093.5
isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma
chr12_+_26195313 10.02 ENST00000422622.3
sarcospan
chr1_+_17580474 10.02 ENST00000375415.5
Rho guanine nucleotide exchange factor 10 like
chr7_+_121873089 10.01 ENST00000651065.1
protein tyrosine phosphatase receptor type Z1
chr8_-_21788853 9.97 ENST00000524240.6
GDNF family receptor alpha 2
chr12_+_112791738 9.89 ENST00000389385.9
rabphilin 3A
chr2_+_218859794 9.87 ENST00000233948.4
Wnt family member 6
chr5_-_11589019 9.81 ENST00000511377.5
catenin delta 2
chr1_-_155562693 9.80 ENST00000368346.7
ENST00000392403.8
ENST00000679333.1
ENST00000679133.1
ASH1 like histone lysine methyltransferase
chr2_-_2326210 9.79 ENST00000647755.1
myelin transcription factor 1 like
chr16_-_970954 9.78 ENST00000543238.5
ENST00000262301.16
lipase maturation factor 1
chr6_+_109095110 9.77 ENST00000521277.5
ENST00000407272.5
ENST00000519286.5
centrosomal protein 57 like 1
chr14_+_74019341 9.70 ENST00000394009.5
ENST00000464394.5
basal body orientation factor 1
chr5_-_11588842 9.65 ENST00000503622.5
catenin delta 2
chr4_+_70721953 9.64 ENST00000381006.8
ENST00000226328.8
RUN and FYVE domain containing 3
chr11_+_131370478 9.62 ENST00000374791.7
ENST00000683400.1
ENST00000436745.5
neurotrimin
chr1_+_145927105 9.61 ENST00000437797.5
ENST00000601726.3
ENST00000599626.5
ENST00000599147.5
ENST00000595494.5
ENST00000595518.5
ENST00000597144.5
ENST00000599469.5
ENST00000598354.5
ENST00000598103.5
ENST00000600340.5
ENST00000630257.2
ENST00000625258.1
LIX1L antisense RNA 1
novel protein, lncRNA-POLR3GL readthrough
chr19_+_35292145 9.56 ENST00000595791.5
ENST00000597035.5
ENST00000537831.2
ENST00000392213.8
myelin associated glycoprotein
chr15_+_74995520 9.55 ENST00000562327.5
ENST00000568018.5
ENST00000425597.8
ENST00000562212.5
ENST00000567920.5
ENST00000566872.5
ENST00000361900.10
secretory carrier membrane protein 5
chr6_-_29633171 9.50 ENST00000377034.9
gamma-aminobutyric acid type B receptor subunit 1
chr2_-_127107259 9.50 ENST00000409400.1
ENST00000357970.7
ENST00000393040.7
ENST00000348750.8
ENST00000259238.8
ENST00000346226.7
ENST00000393041.7
ENST00000351659.7
ENST00000352848.7
bridging integrator 1
chr6_-_29633056 9.50 ENST00000377016.8
gamma-aminobutyric acid type B receptor subunit 1
chr2_+_79512993 9.48 ENST00000496558.5
ENST00000451966.5
ENST00000402739.9
ENST00000629316.2
catenin alpha 2
chr7_-_135510074 9.46 ENST00000428680.6
ENST00000423368.6
ENST00000451834.5
ENST00000361528.8
ENST00000541284.5
ENST00000315544.6
CCR4-NOT transcription complex subunit 4
chrX_-_139642889 9.44 ENST00000370576.9
MCF.2 cell line derived transforming sequence
chr12_-_7091873 9.44 ENST00000538050.5
ENST00000536053.6
complement C1r
chr7_-_22193824 9.44 ENST00000401957.6
Rap guanine nucleotide exchange factor 5
chr10_-_72088972 9.43 ENST00000317376.8
ENST00000412663.5
SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2
chr6_+_125919210 9.39 ENST00000438495.6
nuclear receptor coactivator 7
chr20_+_33235987 9.38 ENST00000375422.6
ENST00000375413.8
ENST00000354297.9
BPI fold containing family A member 1
chr7_-_137343752 9.36 ENST00000393083.2
pleiotrophin
chr12_-_14885845 9.34 ENST00000539261.6
ENST00000228938.5
matrix Gla protein

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
14.7 250.5 GO:0007021 tubulin complex assembly(GO:0007021)
12.7 38.1 GO:1903288 positive regulation of potassium ion import(GO:1903288)
11.7 35.1 GO:1990168 protein K33-linked deubiquitination(GO:1990168)
11.7 46.7 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
9.3 27.8 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
8.9 26.8 GO:1900920 regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
7.9 23.7 GO:0060988 lipid tube assembly(GO:0060988)
6.8 20.5 GO:0060221 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
6.5 110.5 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
6.5 45.5 GO:0070560 protein secretion by platelet(GO:0070560)
6.3 57.0 GO:0016198 axon choice point recognition(GO:0016198)
5.8 17.4 GO:0042704 uterine wall breakdown(GO:0042704) occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
5.3 21.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
5.0 15.1 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
4.9 24.6 GO:0071494 cellular response to UV-C(GO:0071494)
4.6 13.9 GO:0072023 thick ascending limb development(GO:0072023) metanephric thick ascending limb development(GO:0072233)
4.5 18.0 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
4.4 13.3 GO:0014813 skeletal muscle satellite cell commitment(GO:0014813)
4.2 21.1 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
4.0 20.2 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
4.0 15.8 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
4.0 11.9 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
3.9 15.6 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
3.9 11.7 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
3.8 79.0 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
3.6 14.5 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
3.5 10.4 GO:0060875 subpallium cell proliferation in forebrain(GO:0022012) lateral ganglionic eminence cell proliferation(GO:0022018) lambdoid suture morphogenesis(GO:0060366) sagittal suture morphogenesis(GO:0060367) anterior semicircular canal development(GO:0060873) lateral semicircular canal development(GO:0060875)
3.5 3.5 GO:0021775 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
3.2 16.1 GO:1903906 plasma membrane raft distribution(GO:0044855) plasma membrane raft localization(GO:0044856) plasma membrane raft polarization(GO:0044858) regulation of plasma membrane raft polarization(GO:1903906)
3.1 62.5 GO:2000821 regulation of grooming behavior(GO:2000821)
3.1 12.4 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
3.1 9.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
3.1 6.2 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
3.0 12.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
3.0 9.1 GO:1901731 positive regulation of platelet aggregation(GO:1901731)
3.0 9.0 GO:0048691 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
3.0 20.8 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
3.0 47.3 GO:0070445 oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
2.8 36.8 GO:1902548 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
2.8 39.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
2.8 22.2 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
2.8 11.1 GO:0051866 general adaptation syndrome(GO:0051866)
2.8 30.5 GO:0036376 sodium ion export from cell(GO:0036376)
2.8 19.4 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
2.8 19.3 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
2.7 10.8 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
2.7 8.1 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
2.5 22.3 GO:0033578 protein glycosylation in Golgi(GO:0033578)
2.4 7.1 GO:0001983 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978) baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
2.3 9.4 GO:1900229 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
2.3 6.9 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
2.3 6.9 GO:1901877 regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877)
2.3 6.8 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
2.3 6.8 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
2.2 8.9 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
2.2 19.8 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
2.2 26.3 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
2.2 4.4 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
2.2 8.7 GO:0099558 maintenance of synapse structure(GO:0099558)
2.2 6.5 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
2.2 6.5 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
2.1 10.7 GO:0010159 specification of organ position(GO:0010159)
2.1 16.4 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
2.0 30.7 GO:0006600 creatine metabolic process(GO:0006600)
2.0 6.0 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
1.9 5.8 GO:1901624 negative regulation of lymphocyte chemotaxis(GO:1901624)
1.9 28.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.8 11.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
1.8 49.4 GO:0007158 neuron cell-cell adhesion(GO:0007158)
1.8 5.5 GO:0098528 skeletal muscle fiber differentiation(GO:0098528) regulation of skeletal muscle fiber differentiation(GO:1902809)
1.8 20.0 GO:0008354 germ cell migration(GO:0008354)
1.8 7.3 GO:0097167 circadian regulation of translation(GO:0097167)
1.8 12.5 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
1.8 12.5 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
1.8 12.5 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
1.8 8.9 GO:0035645 posterior midgut development(GO:0007497) enteric smooth muscle cell differentiation(GO:0035645)
1.8 12.4 GO:0007042 lysosomal lumen acidification(GO:0007042)
1.8 12.3 GO:0045007 depurination(GO:0045007)
1.7 5.2 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
1.7 5.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
1.7 10.2 GO:0001826 inner cell mass cell differentiation(GO:0001826)
1.7 5.1 GO:2001025 cellular response to mycotoxin(GO:0036146) response to cyclosporin A(GO:1905237) positive regulation of response to drug(GO:2001025)
1.7 6.7 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
1.7 15.0 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
1.7 3.3 GO:0002582 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
1.7 14.9 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
1.6 6.6 GO:0018199 peptidyl-glutamine modification(GO:0018199)
1.6 48.6 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
1.5 3.0 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
1.5 20.7 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
1.5 4.4 GO:1901994 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
1.4 18.8 GO:0070327 thyroid hormone transport(GO:0070327)
1.4 10.0 GO:0006102 isocitrate metabolic process(GO:0006102)
1.4 8.5 GO:0051012 microtubule sliding(GO:0051012)
1.4 7.1 GO:1903392 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
1.4 4.2 GO:0051097 negative regulation of helicase activity(GO:0051097)
1.4 7.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
1.4 8.4 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
1.4 61.6 GO:0008038 neuron recognition(GO:0008038)
1.4 13.9 GO:0045329 carnitine biosynthetic process(GO:0045329)
1.4 4.2 GO:0070845 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
1.4 1.4 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
1.3 5.4 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
1.3 13.5 GO:1990504 dense core granule exocytosis(GO:1990504)
1.3 5.3 GO:1904428 negative regulation of tubulin deacetylation(GO:1904428)
1.3 5.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
1.3 5.2 GO:1900827 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
1.3 20.6 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
1.3 34.0 GO:0034204 lipid translocation(GO:0034204) phospholipid translocation(GO:0045332)
1.3 6.3 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
1.2 3.7 GO:0071812 regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
1.2 34.9 GO:0010669 epithelial structure maintenance(GO:0010669)
1.2 2.5 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
1.2 5.0 GO:0030432 peristalsis(GO:0030432)
1.2 42.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
1.2 9.7 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.2 3.6 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
1.2 11.8 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
1.2 2.3 GO:0060018 astrocyte fate commitment(GO:0060018)
1.2 4.6 GO:0060029 convergent extension involved in organogenesis(GO:0060029)
1.1 9.0 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
1.1 3.4 GO:0019878 lysine biosynthetic process(GO:0009085) lysine biosynthetic process via aminoadipic acid(GO:0019878) L-lysine catabolic process to acetyl-CoA via saccharopine(GO:0033512)
1.1 7.9 GO:0052055 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
1.1 6.7 GO:0015793 glycerol transport(GO:0015793)
1.1 16.6 GO:0014029 neural crest formation(GO:0014029)
1.1 3.3 GO:2001302 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
1.1 29.3 GO:0071420 cellular response to histamine(GO:0071420)
1.1 8.7 GO:0061709 reticulophagy(GO:0061709)
1.1 1.1 GO:0002368 B cell cytokine production(GO:0002368)
1.1 5.3 GO:0070092 regulation of glucagon secretion(GO:0070092)
1.1 5.3 GO:0048105 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105)
1.0 11.5 GO:0047484 regulation of response to osmotic stress(GO:0047484)
1.0 2.1 GO:0048850 hypophysis morphogenesis(GO:0048850) diencephalon morphogenesis(GO:0048852)
1.0 3.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
1.0 19.6 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
1.0 3.0 GO:0033082 extrathymic T cell differentiation(GO:0033078) regulation of extrathymic T cell differentiation(GO:0033082) sebum secreting cell proliferation(GO:1990654)
1.0 7.1 GO:0033591 response to L-ascorbic acid(GO:0033591)
1.0 28.8 GO:0090140 regulation of mitochondrial fission(GO:0090140)
1.0 10.9 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
1.0 4.0 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
1.0 155.9 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
1.0 15.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
1.0 5.8 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
1.0 13.6 GO:0006776 vitamin A metabolic process(GO:0006776)
1.0 2.9 GO:0048664 neuron fate determination(GO:0048664)
1.0 4.8 GO:0030259 lipid glycosylation(GO:0030259)
0.9 13.2 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.9 10.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.9 3.7 GO:0021759 globus pallidus development(GO:0021759)
0.9 2.8 GO:1990451 cellular stress response to acidic pH(GO:1990451)
0.9 22.4 GO:0007628 adult walking behavior(GO:0007628)
0.9 1.8 GO:0035962 response to interleukin-13(GO:0035962)
0.9 16.5 GO:0006071 glycerol metabolic process(GO:0006071)
0.9 7.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.9 10.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.8 2.5 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.8 5.0 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.8 56.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.8 4.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.8 4.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.8 14.6 GO:0097186 amelogenesis(GO:0097186)
0.8 2.4 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.8 3.2 GO:0018879 biphenyl metabolic process(GO:0018879)
0.8 18.2 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.8 7.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.8 5.5 GO:0086016 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.8 6.2 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.8 15.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.8 8.4 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.8 8.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.7 2.2 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.7 16.1 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.7 3.6 GO:1904075 trophectodermal cell proliferation(GO:0001834) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.7 15.2 GO:0060736 prostate gland growth(GO:0060736)
0.7 8.7 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.7 24.3 GO:0007019 microtubule depolymerization(GO:0007019)
0.7 2.8 GO:2000173 negative regulation of dendrite extension(GO:1903860) regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800) negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.7 2.8 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.7 8.3 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.7 18.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.7 6.8 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.7 14.8 GO:0035640 exploration behavior(GO:0035640)
0.7 3.4 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.7 2.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.7 2.0 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.7 4.0 GO:0014807 regulation of somitogenesis(GO:0014807)
0.6 7.1 GO:2000795 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740) negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.6 1.9 GO:0035425 autocrine signaling(GO:0035425)
0.6 1.9 GO:0045900 negative regulation of translational elongation(GO:0045900) positive regulation of mRNA polyadenylation(GO:1900365)
0.6 17.9 GO:0046688 response to copper ion(GO:0046688)
0.6 5.7 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.6 3.8 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.6 6.2 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.6 1.2 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.6 1.9 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.6 2.5 GO:0071725 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.6 8.0 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.6 1.2 GO:0002876 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) positive regulation of chronic inflammatory response to antigenic stimulus(GO:0002876)
0.6 6.0 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.6 16.2 GO:0048665 neuron fate specification(GO:0048665)
0.6 2.4 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.6 2.4 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.6 6.0 GO:0016576 histone dephosphorylation(GO:0016576)
0.6 15.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.6 6.1 GO:0071313 cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.5 4.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.5 1.6 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.5 4.9 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.5 12.8 GO:0030517 negative regulation of axon extension(GO:0030517)
0.5 2.1 GO:0001692 histamine metabolic process(GO:0001692)
0.5 1.5 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.5 0.5 GO:2000538 positive regulation of thymocyte migration(GO:2000412) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.5 1.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.5 9.6 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.5 13.5 GO:0001502 cartilage condensation(GO:0001502)
0.5 2.5 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.5 8.4 GO:0003322 pancreatic A cell development(GO:0003322)
0.5 1.4 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.5 7.7 GO:0042340 keratan sulfate catabolic process(GO:0042340)
0.5 22.0 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.5 0.9 GO:2000977 regulation of forebrain neuron differentiation(GO:2000977)
0.5 3.7 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.5 4.2 GO:0048625 myoblast fate commitment(GO:0048625)
0.5 10.9 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.5 1.8 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.4 1.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.4 29.0 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.4 9.6 GO:0050771 negative regulation of axonogenesis(GO:0050771)
0.4 1.8 GO:0002879 acute inflammatory response to non-antigenic stimulus(GO:0002525) regulation of acute inflammatory response to non-antigenic stimulus(GO:0002877) positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.4 1.7 GO:0002933 lipid hydroxylation(GO:0002933)
0.4 6.7 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.4 7.1 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.4 2.5 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.4 1.2 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.4 0.8 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.4 6.9 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.4 6.4 GO:0005513 detection of calcium ion(GO:0005513)
0.4 12.8 GO:0010107 potassium ion import(GO:0010107)
0.4 3.2 GO:0001573 ganglioside metabolic process(GO:0001573)
0.4 6.3 GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.4 2.0 GO:0042048 olfactory behavior(GO:0042048)
0.4 22.5 GO:0006458 'de novo' protein folding(GO:0006458)
0.4 4.6 GO:2000178 negative regulation of neural precursor cell proliferation(GO:2000178)
0.4 11.2 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.4 3.4 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.4 3.4 GO:0086024 adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024)
0.4 5.3 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.4 3.0 GO:0070235 regulation of activation-induced cell death of T cells(GO:0070235) negative regulation of activation-induced cell death of T cells(GO:0070236)
0.4 10.5 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.4 6.8 GO:0009812 flavonoid metabolic process(GO:0009812)
0.4 4.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.4 0.7 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.4 1.1 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.4 1.4 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.4 4.7 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.4 3.9 GO:0070571 negative regulation of axon regeneration(GO:0048681) negative regulation of neuron projection regeneration(GO:0070571)
0.3 6.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.3 16.8 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.3 2.0 GO:0072592 oxygen metabolic process(GO:0072592)
0.3 4.3 GO:0044804 nucleophagy(GO:0044804)
0.3 1.0 GO:1902724 mineralocorticoid receptor signaling pathway(GO:0031959) regulation of growth hormone receptor signaling pathway(GO:0060398) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.3 5.4 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.3 2.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.3 11.7 GO:0097120 receptor localization to synapse(GO:0097120)
0.3 5.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.3 2.8 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.3 3.4 GO:0008090 retrograde axonal transport(GO:0008090)
0.3 14.2 GO:0003197 endocardial cushion development(GO:0003197)
0.3 3.7 GO:0015074 DNA integration(GO:0015074)
0.3 6.1 GO:0030826 regulation of cGMP biosynthetic process(GO:0030826)
0.3 0.9 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.3 2.1 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.3 5.0 GO:0003416 endochondral bone growth(GO:0003416)
0.3 9.4 GO:0030516 regulation of axon extension(GO:0030516)
0.3 0.6 GO:0048865 stem cell fate commitment(GO:0048865)
0.3 18.4 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.3 1.4 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.3 5.4 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)
0.3 0.8 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.3 12.6 GO:0010761 fibroblast migration(GO:0010761)
0.3 3.6 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.3 3.3 GO:0000050 urea cycle(GO:0000050)
0.3 7.7 GO:0014898 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.3 1.4 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.3 3.8 GO:0010818 T cell chemotaxis(GO:0010818)
0.3 2.1 GO:0006203 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
0.3 0.5 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.3 0.3 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.3 3.3 GO:0050919 negative chemotaxis(GO:0050919)
0.3 3.1 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.3 16.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.3 2.8 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.3 3.0 GO:0001778 plasma membrane repair(GO:0001778)
0.3 0.5 GO:0060527 prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.3 2.0 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 6.7 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.2 1.7 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.2 12.8 GO:0002088 lens development in camera-type eye(GO:0002088)
0.2 1.6 GO:0042791 5S class rRNA transcription from RNA polymerase III type 1 promoter(GO:0042791) tRNA transcription from RNA polymerase III promoter(GO:0042797)
0.2 8.7 GO:0035082 axoneme assembly(GO:0035082)
0.2 0.5 GO:0072709 cellular response to sorbitol(GO:0072709)
0.2 2.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.2 0.4 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.2 4.6 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.2 29.5 GO:0046718 viral entry into host cell(GO:0046718)
0.2 6.3 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.2 1.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.2 6.8 GO:0086010 membrane depolarization during action potential(GO:0086010)
0.2 1.3 GO:0070942 neutrophil mediated cytotoxicity(GO:0070942) neutrophil mediated killing of symbiont cell(GO:0070943) neutrophil mediated killing of bacterium(GO:0070944)
0.2 0.9 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.2 0.8 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
0.2 1.1 GO:0060155 platelet dense granule organization(GO:0060155)
0.2 0.7 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.2 6.6 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.2 0.5 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.2 2.2 GO:0006700 C21-steroid hormone biosynthetic process(GO:0006700)
0.2 12.5 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.2 0.5 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.2 2.9 GO:0044458 motile cilium assembly(GO:0044458)
0.2 0.3 GO:0021800 cerebral cortex tangential migration(GO:0021800) cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2 1.8 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.2 8.5 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.2 16.5 GO:0005977 glycogen metabolic process(GO:0005977)
0.2 3.3 GO:0035728 response to hepatocyte growth factor(GO:0035728)
0.2 16.0 GO:0090630 activation of GTPase activity(GO:0090630)
0.2 1.0 GO:0001946 lymphangiogenesis(GO:0001946)
0.2 3.2 GO:0016048 detection of temperature stimulus(GO:0016048)
0.2 2.2 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.2 2.2 GO:0006020 inositol metabolic process(GO:0006020)
0.2 3.3 GO:0006884 cell volume homeostasis(GO:0006884)
0.2 6.4 GO:0016486 peptide hormone processing(GO:0016486)
0.2 4.2 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.2 2.7 GO:1900038 negative regulation of cellular response to hypoxia(GO:1900038)
0.2 11.7 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic(GO:0090502)
0.1 0.6 GO:0045144 meiotic sister chromatid segregation(GO:0045144)
0.1 7.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 2.5 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.7 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 6.1 GO:1901385 regulation of voltage-gated calcium channel activity(GO:1901385)
0.1 6.4 GO:0021954 central nervous system neuron development(GO:0021954)
0.1 0.9 GO:0051775 response to redox state(GO:0051775)
0.1 1.6 GO:0021670 lateral ventricle development(GO:0021670)
0.1 2.6 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.8 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 5.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 3.6 GO:0018149 peptide cross-linking(GO:0018149)
0.1 3.8 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 1.6 GO:0016242 negative regulation of macroautophagy(GO:0016242)
0.1 2.6 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.1 0.4 GO:1902462 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 1.4 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.1 1.6 GO:0042268 regulation of cytolysis(GO:0042268)
0.1 2.6 GO:0035036 sperm-egg recognition(GO:0035036)
0.1 1.7 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 0.3 GO:0038043 interleukin-5-mediated signaling pathway(GO:0038043)
0.1 2.6 GO:0014072 response to isoquinoline alkaloid(GO:0014072) response to morphine(GO:0043278)
0.1 3.6 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 2.0 GO:0007340 acrosome reaction(GO:0007340)
0.1 1.5 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.1 0.4 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314)
0.1 0.7 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.1 0.4 GO:0098911 regulation of ventricular cardiac muscle cell action potential(GO:0098911)
0.1 5.6 GO:0015701 bicarbonate transport(GO:0015701)
0.1 1.5 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.1 0.4 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 3.5 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.1 12.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.1 1.2 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.9 GO:0002347 response to tumor cell(GO:0002347)
0.1 1.0 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 0.7 GO:0033015 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1 4.2 GO:0016266 O-glycan processing(GO:0016266)
0.1 2.1 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.1 0.3 GO:0070459 prolactin secretion(GO:0070459)
0.1 1.0 GO:0035855 megakaryocyte development(GO:0035855)
0.1 3.8 GO:0006826 iron ion transport(GO:0006826)
0.1 3.7 GO:1902476 chloride transmembrane transport(GO:1902476)
0.1 27.2 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.1 0.6 GO:0071542 dopaminergic neuron differentiation(GO:0071542)
0.1 1.6 GO:0060711 labyrinthine layer development(GO:0060711)
0.1 5.0 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)
0.0 1.0 GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter(GO:0060261)
0.0 1.7 GO:0070098 chemokine-mediated signaling pathway(GO:0070098)
0.0 2.2 GO:0030010 establishment of cell polarity(GO:0030010)
0.0 2.1 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 1.9 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.7 GO:0021510 spinal cord development(GO:0021510)
0.0 0.2 GO:0030238 male sex determination(GO:0030238)
0.0 0.2 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.9 GO:0030449 regulation of complement activation(GO:0030449)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
17.4 279.0 GO:0097512 cardiac myofibril(GO:0097512)
12.0 36.0 GO:0098843 postsynaptic endocytic zone(GO:0098843)
11.8 58.8 GO:0072534 perineuronal net(GO:0072534)
9.5 57.0 GO:0032584 growth cone membrane(GO:0032584)
7.9 23.7 GO:0060987 lipid tube(GO:0060987)
6.2 18.7 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
5.5 99.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
4.8 19.0 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
4.4 17.7 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
4.0 11.9 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
2.7 21.8 GO:0045179 apical cortex(GO:0045179)
2.7 16.1 GO:0070545 PeBoW complex(GO:0070545)
2.6 65.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
2.6 36.4 GO:0098839 postsynaptic density membrane(GO:0098839)
2.5 32.5 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
2.1 6.3 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
1.8 14.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
1.8 10.7 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
1.7 3.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
1.7 8.3 GO:0036128 CatSper complex(GO:0036128)
1.6 21.0 GO:0035749 myelin sheath adaxonal region(GO:0035749)
1.5 7.7 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
1.5 6.2 GO:0090533 cation-transporting ATPase complex(GO:0090533)
1.4 7.1 GO:0005826 actomyosin contractile ring(GO:0005826)
1.4 34.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
1.4 4.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
1.3 16.2 GO:0043083 synaptic cleft(GO:0043083)
1.3 25.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
1.3 20.2 GO:0042583 chromaffin granule(GO:0042583)
1.2 6.9 GO:0035253 ciliary rootlet(GO:0035253)
1.1 4.6 GO:0034678 integrin alpha8-beta1 complex(GO:0034678)
1.1 6.8 GO:0033061 DNA recombinase mediator complex(GO:0033061) Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
1.1 11.2 GO:0005614 interstitial matrix(GO:0005614)
1.1 11.1 GO:0070852 cell body fiber(GO:0070852)
1.1 3.2 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
1.0 9.4 GO:0032133 chromosome passenger complex(GO:0032133)
1.0 8.3 GO:0061700 GATOR2 complex(GO:0061700)
1.0 235.0 GO:0030426 growth cone(GO:0030426)
1.0 8.2 GO:0005579 membrane attack complex(GO:0005579)
1.0 6.0 GO:0005594 collagen type IX trimer(GO:0005594)
1.0 6.9 GO:0030893 meiotic cohesin complex(GO:0030893)
1.0 5.8 GO:0032593 insulin-responsive compartment(GO:0032593)
1.0 6.7 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.9 5.5 GO:1990769 proximal neuron projection(GO:1990769)
0.9 11.1 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.9 9.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.9 4.4 GO:0072687 meiotic spindle(GO:0072687)
0.9 12.9 GO:0030478 actin cap(GO:0030478)
0.8 3.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.8 12.4 GO:0030663 COPI-coated vesicle membrane(GO:0030663)
0.8 6.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.7 5.2 GO:0031143 pseudopodium(GO:0031143)
0.7 7.3 GO:0033018 sarcoplasmic reticulum lumen(GO:0033018)
0.7 120.1 GO:0031225 anchored component of membrane(GO:0031225)
0.7 28.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.7 3.4 GO:0031673 H zone(GO:0031673)
0.6 2.8 GO:0071438 invadopodium membrane(GO:0071438)
0.5 7.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.5 9.8 GO:0005922 connexon complex(GO:0005922)
0.5 5.3 GO:0030427 site of polarized growth(GO:0030427)
0.5 2.7 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.5 32.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.5 22.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.5 5.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.5 10.0 GO:0000974 Prp19 complex(GO:0000974)
0.5 4.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.4 18.2 GO:0016592 mediator complex(GO:0016592)
0.4 2.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.4 3.9 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.4 37.2 GO:0042734 presynaptic membrane(GO:0042734)
0.4 35.7 GO:0043195 terminal bouton(GO:0043195)
0.4 4.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.4 4.0 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.4 9.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.4 7.5 GO:0032982 myosin filament(GO:0032982)
0.4 6.1 GO:0035102 PRC1 complex(GO:0035102)
0.4 15.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.4 1.8 GO:0005921 gap junction(GO:0005921)
0.4 1.8 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.4 4.7 GO:0031618 chromocenter(GO:0010369) nuclear pericentric heterochromatin(GO:0031618)
0.4 25.9 GO:0055038 recycling endosome membrane(GO:0055038)
0.4 4.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.3 6.3 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.3 4.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.3 4.1 GO:0005577 fibrinogen complex(GO:0005577)
0.3 6.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.3 3.0 GO:0031209 SCAR complex(GO:0031209)
0.3 22.7 GO:0005796 Golgi lumen(GO:0005796)
0.3 1.0 GO:0005674 transcription factor TFIIF complex(GO:0005674)
0.3 19.2 GO:0035577 azurophil granule membrane(GO:0035577)
0.3 1.8 GO:0016342 catenin complex(GO:0016342)
0.3 0.6 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.3 37.2 GO:0043204 perikaryon(GO:0043204)
0.3 11.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.3 7.1 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.3 3.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.3 2.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 6.4 GO:0097542 ciliary tip(GO:0097542)
0.2 8.2 GO:0035861 site of double-strand break(GO:0035861)
0.2 4.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.2 1.6 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.2 0.7 GO:0016939 kinesin II complex(GO:0016939)
0.2 15.0 GO:0005776 autophagosome(GO:0005776)
0.2 2.7 GO:0097486 multivesicular body lumen(GO:0097486)
0.2 2.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.2 4.3 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.2 25.3 GO:0005923 bicellular tight junction(GO:0005923)
0.2 2.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.2 3.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 47.2 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.2 2.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.2 3.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.2 64.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.2 1.2 GO:0060077 inhibitory synapse(GO:0060077)
0.2 5.5 GO:0009925 basal plasma membrane(GO:0009925)
0.2 5.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.2 4.7 GO:0005779 integral component of peroxisomal membrane(GO:0005779) intrinsic component of peroxisomal membrane(GO:0031231)
0.2 8.3 GO:0030315 T-tubule(GO:0030315)
0.2 8.2 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2 5.2 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.2 3.6 GO:0030673 axolemma(GO:0030673)
0.1 3.7 GO:0002080 acrosomal membrane(GO:0002080)
0.1 7.1 GO:0005902 microvillus(GO:0005902)
0.1 5.9 GO:0005811 lipid particle(GO:0005811)
0.1 4.0 GO:0034451 centriolar satellite(GO:0034451)
0.1 1.0 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 5.4 GO:0001533 cornified envelope(GO:0001533)
0.1 0.8 GO:0070160 occluding junction(GO:0070160)
0.1 20.7 GO:0098793 presynapse(GO:0098793)
0.1 1.4 GO:0000242 pericentriolar material(GO:0000242)
0.1 1.5 GO:0043296 apical junction complex(GO:0043296)
0.1 1.4 GO:0030056 hemidesmosome(GO:0030056)
0.1 10.1 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 6.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 6.0 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.8 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 5.1 GO:0016528 sarcoplasm(GO:0016528)
0.1 1.1 GO:0042629 mast cell granule(GO:0042629)
0.1 1.1 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 8.7 GO:0034705 voltage-gated potassium channel complex(GO:0008076) potassium channel complex(GO:0034705)
0.1 0.7 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 5.9 GO:0009897 external side of plasma membrane(GO:0009897)
0.1 10.3 GO:0030424 axon(GO:0030424)
0.1 5.9 GO:0036064 ciliary basal body(GO:0036064)
0.1 0.5 GO:0036021 endolysosome lumen(GO:0036021)
0.1 2.1 GO:0008305 integrin complex(GO:0008305)
0.1 4.7 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 2.8 GO:0044438 microbody part(GO:0044438) peroxisomal part(GO:0044439)
0.1 11.0 GO:0005802 trans-Golgi network(GO:0005802)
0.1 2.9 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.7 GO:0034707 chloride channel complex(GO:0034707)
0.1 16.1 GO:0044297 cell body(GO:0044297)
0.0 3.5 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 0.9 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 1.0 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.5 GO:0005876 spindle microtubule(GO:0005876)
0.0 2.6 GO:0098794 postsynapse(GO:0098794)
0.0 0.5 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 5.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 33.9 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 4.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 4.9 GO:0043005 neuron projection(GO:0043005)
0.0 0.4 GO:0031904 endosome lumen(GO:0031904)
0.0 2.0 GO:0005875 microtubule associated complex(GO:0005875)
0.0 1.2 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 44.1 GO:0016021 integral component of membrane(GO:0016021)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
8.6 257.5 GO:0005212 structural constituent of eye lens(GO:0005212)
7.9 23.8 GO:0030350 iron-responsive element binding(GO:0030350)
6.3 56.8 GO:0035727 lysophosphatidic acid binding(GO:0035727)
6.3 81.6 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
6.1 30.3 GO:0004522 ribonuclease A activity(GO:0004522)
6.0 24.2 GO:0097001 ceramide binding(GO:0097001)
5.8 23.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
5.4 48.9 GO:0030274 LIM domain binding(GO:0030274)
5.3 42.7 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
4.8 14.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
4.8 19.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
4.7 18.7 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
4.6 13.9 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
4.6 27.6 GO:1904315 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
4.2 12.5 GO:0017129 triglyceride binding(GO:0017129)
4.1 32.4 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
4.0 11.9 GO:0004157 dihydropyrimidinase activity(GO:0004157)
4.0 11.9 GO:0030305 heparanase activity(GO:0030305)
4.0 47.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
3.9 11.8 GO:0004144 diacylglycerol O-acyltransferase activity(GO:0004144)
3.9 31.2 GO:0004111 creatine kinase activity(GO:0004111)
3.5 17.4 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
3.4 13.7 GO:0016639 oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor(GO:0016639)
3.4 27.0 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
3.3 20.0 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
3.3 65.0 GO:0097109 neuroligin family protein binding(GO:0097109)
3.2 15.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
3.1 18.7 GO:0030172 troponin C binding(GO:0030172)
3.1 12.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
3.1 12.3 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
2.9 17.7 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
2.8 8.4 GO:0036505 prosaposin receptor activity(GO:0036505)
2.8 19.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
2.7 8.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
2.6 18.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
2.6 20.8 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
2.6 7.7 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
2.6 15.4 GO:0000285 1-phosphatidylinositol-3-phosphate 5-kinase activity(GO:0000285)
2.5 20.2 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
2.5 10.0 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
2.2 13.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
2.1 19.2 GO:0004565 beta-galactosidase activity(GO:0004565)
2.1 8.3 GO:0070728 leucine binding(GO:0070728)
2.1 64.4 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
2.0 18.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
2.0 28.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
2.0 18.0 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
2.0 25.6 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
2.0 5.9 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
1.9 5.8 GO:0008169 C-methyltransferase activity(GO:0008169)
1.9 5.8 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
1.9 21.0 GO:0033691 sialic acid binding(GO:0033691)
1.8 9.0 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
1.8 7.1 GO:0031716 calcitonin receptor binding(GO:0031716)
1.8 14.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
1.7 17.4 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.7 5.2 GO:0005502 11-cis retinal binding(GO:0005502)
1.7 35.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
1.7 6.7 GO:0015254 glycerol channel activity(GO:0015254)
1.6 4.9 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
1.6 22.6 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
1.6 11.1 GO:0001515 opioid peptide activity(GO:0001515)
1.5 10.8 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
1.5 10.7 GO:0001849 complement component C1q binding(GO:0001849)
1.4 39.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
1.4 10.0 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
1.4 7.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
1.4 2.8 GO:0004948 calcitonin receptor activity(GO:0004948)
1.4 5.5 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
1.4 4.1 GO:0061609 fructose-1-phosphate aldolase activity(GO:0061609)
1.3 25.0 GO:0031702 type 1 angiotensin receptor binding(GO:0031702)
1.3 9.2 GO:0070891 lipoteichoic acid binding(GO:0070891)
1.3 15.6 GO:0004075 biotin carboxylase activity(GO:0004075)
1.3 5.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
1.3 45.7 GO:0071837 HMG box domain binding(GO:0071837)
1.2 14.6 GO:0008430 selenium binding(GO:0008430)
1.2 15.8 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
1.2 21.9 GO:0043560 insulin receptor substrate binding(GO:0043560)
1.2 10.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
1.2 24.2 GO:0005112 Notch binding(GO:0005112)
1.1 12.5 GO:0001968 fibronectin binding(GO:0001968)
1.1 10.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
1.1 11.1 GO:0030215 semaphorin receptor binding(GO:0030215)
1.1 24.4 GO:0051787 misfolded protein binding(GO:0051787)
1.1 3.3 GO:0047977 hepoxilin-epoxide hydrolase activity(GO:0047977)
1.1 10.8 GO:0030911 TPR domain binding(GO:0030911)
1.1 8.4 GO:0005000 vasopressin receptor activity(GO:0005000)
1.0 9.4 GO:0035174 histone serine kinase activity(GO:0035174)
1.0 5.2 GO:0051373 FATZ binding(GO:0051373)
1.0 11.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
1.0 15.1 GO:0031432 titin binding(GO:0031432)
1.0 11.1 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
1.0 17.9 GO:0038191 neuropilin binding(GO:0038191)
1.0 6.8 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.9 2.8 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.9 3.6 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.9 6.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.9 18.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.9 9.6 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.9 4.3 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.9 15.4 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.8 6.7 GO:0050816 phosphothreonine binding(GO:0050816)
0.8 9.1 GO:0015250 water channel activity(GO:0015250)
0.8 3.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.8 7.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.8 2.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.8 6.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.8 6.9 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.7 3.7 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.7 6.3 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.7 4.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.7 5.4 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.7 5.4 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.7 6.0 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.7 6.0 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.7 2.7 GO:0043515 kinetochore binding(GO:0043515)
0.7 7.2 GO:0038132 neuregulin binding(GO:0038132)
0.7 9.8 GO:0005243 gap junction channel activity(GO:0005243)
0.6 4.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.6 8.4 GO:0016918 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.6 5.0 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.6 3.1 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.6 1.9 GO:0005042 netrin receptor activity(GO:0005042)
0.6 35.0 GO:0030507 spectrin binding(GO:0030507)
0.6 14.0 GO:0031005 filamin binding(GO:0031005)
0.6 16.4 GO:0030506 ankyrin binding(GO:0030506)
0.6 13.9 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.6 4.2 GO:0005499 vitamin D binding(GO:0005499)
0.6 5.4 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.6 1.8 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.6 2.4 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.6 12.2 GO:0002162 dystroglycan binding(GO:0002162)
0.6 1.7 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.6 3.4 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.6 10.6 GO:0008066 glutamate receptor activity(GO:0008066)
0.6 43.6 GO:0050840 extracellular matrix binding(GO:0050840)
0.5 8.7 GO:0044548 S100 protein binding(GO:0044548)
0.5 2.1 GO:0008832 dGTPase activity(GO:0008832) triphosphoric monoester hydrolase activity(GO:0016793) guanyl deoxyribonucleotide binding(GO:0032560) dGTP binding(GO:0032567)
0.5 0.5 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.5 3.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.5 3.1 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.5 2.0 GO:0071532 ankyrin repeat binding(GO:0071532)
0.5 2.4 GO:0031711 tripeptidyl-peptidase activity(GO:0008240) peptidyl-dipeptidase activity(GO:0008241) bradykinin receptor binding(GO:0031711) metallodipeptidase activity(GO:0070573)
0.5 0.9 GO:0050692 DBD domain binding(GO:0050692)
0.5 5.7 GO:0004875 complement receptor activity(GO:0004875)
0.5 11.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.5 4.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.5 6.8 GO:0005344 oxygen transporter activity(GO:0005344)
0.4 1.3 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.4 2.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.4 39.8 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.4 4.9 GO:0039706 co-receptor binding(GO:0039706)
0.4 26.0 GO:0015485 cholesterol binding(GO:0015485)
0.4 5.1 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.4 7.1 GO:0001222 transcription corepressor binding(GO:0001222)
0.4 48.3 GO:0001618 virus receptor activity(GO:0001618)
0.4 4.0 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.4 10.1 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.4 2.2 GO:0017127 cholesterol transporter activity(GO:0017127)
0.4 2.6 GO:1990932 5.8S rRNA binding(GO:1990932)
0.4 17.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.4 4.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.4 1.4 GO:0004925 prolactin receptor activity(GO:0004925)
0.4 30.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.4 1.4 GO:0032934 sterol binding(GO:0032934)
0.4 4.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.3 1.7 GO:0004447 iodide peroxidase activity(GO:0004447)
0.3 4.8 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.3 5.7 GO:0016805 dipeptidase activity(GO:0016805)
0.3 18.8 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.3 1.3 GO:0005148 prolactin receptor binding(GO:0005148)
0.3 5.1 GO:0044213 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.3 27.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.3 4.7 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.3 4.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.3 5.6 GO:0048156 tau protein binding(GO:0048156)
0.3 18.5 GO:0030331 estrogen receptor binding(GO:0030331)
0.3 16.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.3 2.4 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.3 3.3 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.3 24.1 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.3 5.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.3 7.9 GO:0000146 microfilament motor activity(GO:0000146)
0.3 2.8 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.3 13.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.3 4.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.3 4.2 GO:0019215 intermediate filament binding(GO:0019215)
0.3 30.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.3 202.9 GO:0005509 calcium ion binding(GO:0005509)
0.3 12.8 GO:0016859 cis-trans isomerase activity(GO:0016859)
0.2 2.0 GO:0051430 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.2 0.7 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.2 6.3 GO:0001972 retinoic acid binding(GO:0001972)
0.2 1.8 GO:0034713 type I transforming growth factor beta receptor binding(GO:0034713)
0.2 25.8 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.2 6.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 5.6 GO:0005109 frizzled binding(GO:0005109)
0.2 19.0 GO:0008013 beta-catenin binding(GO:0008013)
0.2 0.4 GO:0005497 androgen binding(GO:0005497)
0.2 2.5 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.2 6.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 3.4 GO:0008320 protein transmembrane transporter activity(GO:0008320)
0.2 5.1 GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen(GO:0016712)
0.2 7.7 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.2 7.7 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 8.8 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.2 2.6 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.2 6.9 GO:0030145 manganese ion binding(GO:0030145)
0.2 3.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.2 1.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 2.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 11.1 GO:0004620 phospholipase activity(GO:0004620)
0.1 0.6 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.1 5.3 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.1 0.7 GO:0019862 IgA binding(GO:0019862)
0.1 46.0 GO:0005096 GTPase activator activity(GO:0005096)
0.1 1.0 GO:0019992 diacylglycerol binding(GO:0019992)
0.1 2.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 3.4 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 0.4 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.1 4.2 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.1 5.2 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.1 6.9 GO:0019894 kinesin binding(GO:0019894)
0.1 2.6 GO:0050321 tau-protein kinase activity(GO:0050321)
0.1 23.8 GO:0003729 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.1 1.0 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.1 1.5 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.1 7.5 GO:0002039 p53 binding(GO:0002039)
0.1 0.3 GO:0004914 interleukin-5 receptor activity(GO:0004914)
0.1 1.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 3.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.7 GO:0016004 phospholipase activator activity(GO:0016004)
0.1 5.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.8 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.1 3.0 GO:0048487 beta-tubulin binding(GO:0048487)
0.1 0.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.4 GO:0051525 NFAT protein binding(GO:0051525)
0.1 2.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 1.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 2.0 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 8.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.3 GO:0031013 troponin I binding(GO:0031013)
0.1 1.5 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.1 2.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.1 5.5 GO:0051087 chaperone binding(GO:0051087)
0.1 14.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.6 GO:0015172 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.1 1.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.1 11.8 GO:0008017 microtubule binding(GO:0008017)
0.1 1.4 GO:0019956 chemokine binding(GO:0019956)
0.0 21.3 GO:0004930 G-protein coupled receptor activity(GO:0004930)
0.0 3.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 1.0 GO:0046961 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 2.9 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.8 GO:0030170 pyridoxal phosphate binding(GO:0030170)
0.0 0.9 GO:0003774 motor activity(GO:0003774)
0.0 0.6 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.1 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.9 GO:0004004 ATP-dependent RNA helicase activity(GO:0004004)
0.0 1.8 GO:0005200 structural constituent of cytoskeleton(GO:0005200)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 108.9 PID NCADHERIN PATHWAY N-cadherin signaling events
1.1 6.8 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
1.0 50.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.9 40.6 ST GA12 PATHWAY G alpha 12 Pathway
0.8 6.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.7 31.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.6 16.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.6 10.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.6 40.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.5 8.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.4 29.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.4 28.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.4 5.9 PID NECTIN PATHWAY Nectin adhesion pathway
0.4 5.1 PID IL27 PATHWAY IL27-mediated signaling events
0.4 4.2 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.3 47.3 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.3 20.0 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.3 5.0 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.3 10.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.3 5.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3 62.7 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.3 15.2 PID ILK PATHWAY Integrin-linked kinase signaling
0.3 7.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.3 15.1 PID ATR PATHWAY ATR signaling pathway
0.3 3.6 PID IGF1 PATHWAY IGF1 pathway
0.3 8.5 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.3 16.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.2 16.5 PID LKB1 PATHWAY LKB1 signaling events
0.2 30.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.2 19.8 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.2 9.0 PID FGF PATHWAY FGF signaling pathway
0.2 3.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.2 6.8 PID SHP2 PATHWAY SHP2 signaling
0.2 2.8 PID RAC1 PATHWAY RAC1 signaling pathway
0.2 14.2 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.2 4.0 ST GAQ PATHWAY G alpha q Pathway
0.2 6.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.2 6.3 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.2 11.5 PID AURORA B PATHWAY Aurora B signaling
0.2 8.4 SIG CHEMOTAXIS Genes related to chemotaxis
0.2 2.9 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.2 4.4 PID REELIN PATHWAY Reelin signaling pathway
0.2 7.1 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.2 10.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.2 2.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.2 3.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.2 11.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 6.0 PID IL23 PATHWAY IL23-mediated signaling events
0.1 3.1 PID ARF 3PATHWAY Arf1 pathway
0.1 1.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 3.0 PID MYC PATHWAY C-MYC pathway
0.1 2.8 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 3.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 2.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.1 12.9 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.1 25.9 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 1.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 12.5 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 3.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.1 1.5 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 0.3 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.8 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.4 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 11.4 NABA MATRISOME ASSOCIATED Ensemble of genes encoding ECM-associated proteins including ECM-affilaited proteins, ECM regulators and secreted factors
0.0 1.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.4 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.4 PID HES HEY PATHWAY Notch-mediated HES/HEY network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 118.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
2.1 42.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
1.5 38.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
1.3 6.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
1.3 27.8 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
1.1 7.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
1.1 21.1 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
1.0 42.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.9 25.1 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.9 34.7 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.9 31.4 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.9 35.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.9 52.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.8 18.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.7 5.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.6 7.7 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.6 15.8 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.6 14.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.6 12.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.6 10.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.6 18.4 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.6 2.8 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.6 24.8 REACTOME AMYLOIDS Genes involved in Amyloids
0.5 13.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.5 9.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.5 11.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.5 7.8 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.5 18.6 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.5 6.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.5 8.7 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.5 1.5 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.5 9.0 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.5 4.0 REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.5 9.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.4 15.4 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.4 4.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.4 30.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.4 19.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.4 2.9 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.4 13.7 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.4 5.0 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.4 8.3 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.4 22.4 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.3 67.3 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.3 5.7 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.3 47.2 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.3 6.7 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.3 4.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.3 12.8 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.3 7.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.3 11.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.3 3.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.3 5.0 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.3 3.6 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.3 4.8 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.2 10.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.2 10.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.2 3.5 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.2 23.4 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.2 4.2 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.2 8.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.2 3.0 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.2 13.7 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 21.3 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.2 1.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.2 4.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.2 3.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 6.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.2 2.5 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.2 1.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.2 2.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.2 1.1 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.2 6.0 REACTOME G ALPHA S SIGNALLING EVENTS Genes involved in G alpha (s) signalling events
0.2 11.8 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.1 4.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 4.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 3.9 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 3.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.0 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 4.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 7.3 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 4.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 1.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 5.2 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 13.1 REACTOME TRANSMISSION ACROSS CHEMICAL SYNAPSES Genes involved in Transmission across Chemical Synapses
0.1 0.7 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 15.0 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 2.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.1 1.7 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.1 2.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 4.6 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.1 1.9 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 1.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 1.3 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.5 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 2.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.8 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo