ISMARA results: FOXA1

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avrg: GNF SymAtlas + NCI-60 cancer cell lines, human (Su, 2004; Ross, 2000)

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Results for FOXA1

Z-value: 2.00

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Transcription factors associated with FOXA1

Gene Symbol	Gene ID	Gene Info
FOXA1 Ensembl NCBI GeneCards UniProt	ENSG00000129514.8	FOXA1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
FOXA1	hg38_v1_chr14_-_37595224_37595281	0.43	3.7e-11	Click!

Activity profile of FOXA1 motif

Sorted Z-values of FOXA1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA1

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Top targets:

Promoter	Score	Transcript	Gene	Gene Info
chr17_-_41528293 Show fit	34.85	ENST00000455635.1 ENST00000361566.7	KRT19 Ensembl NCBI GeneCards UniProt Show fit	keratin 19
chr5_+_136058849 Show fit	29.56	ENST00000508076.5	TGFBI Ensembl NCBI GeneCards UniProt Show fit	transforming growth factor beta induced
chr18_+_3449620 Show fit	27.92	ENST00000405385.7	TGIF1 Ensembl NCBI GeneCards UniProt Show fit	TGFB induced factor homeobox 1
chr17_-_28368012 Show fit	22.96	ENST00000555059.2	ENSG00000273171.1 Ensembl NCBI GeneCards UniProt Show fit	novel protein, readthrough between VTN and SEBOX
chr19_+_18386150 Show fit	22.44	ENST00000252809.3	GDF15 Ensembl NCBI GeneCards UniProt Show fit	growth differentiation factor 15
chr12_-_71157872 Show fit	16.61	ENST00000546561.2	TSPAN8 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 8
chr12_-_71157992 Show fit	16.05	ENST00000247829.8	TSPAN8 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 8
chr12_-_89352395 Show fit	15.43	ENST00000308385.6	DUSP6 Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 6
chr12_-_89352487 Show fit	14.16	ENST00000548755.1 ENST00000279488.8	DUSP6 Ensembl NCBI GeneCards UniProt Show fit	dual specificity phosphatase 6
chr12_-_52949818 Show fit	13.42	ENST00000546897.5 ENST00000552551.5	KRT8 Ensembl NCBI GeneCards UniProt Show fit	keratin 8
chr19_-_48390847 Show fit	12.82	ENST00000597017.5	KDELR1 Ensembl NCBI GeneCards UniProt Show fit	KDEL endoplasmic reticulum protein retention receptor 1
chr6_+_36676489 Show fit	12.19	ENST00000448526.6	CDKN1A Ensembl NCBI GeneCards UniProt Show fit	cyclin dependent kinase inhibitor 1A
chr7_+_73828160 Show fit	11.79	ENST00000431918.1	CLDN4 Ensembl NCBI GeneCards UniProt Show fit	claudin 4
chr15_+_96325935 Show fit	11.74	ENST00000421109.6	NR2F2 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 2 group F member 2
chr5_+_96663010 Show fit	11.54	ENST00000506811.5 ENST00000514055.5 ENST00000508608.6	CAST Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr8_+_125430333 Show fit	11.49	ENST00000311922.4	TRIB1 Ensembl NCBI GeneCards UniProt Show fit	tribbles pseudokinase 1
chr5_+_96662969 Show fit	10.18	ENST00000514845.5 ENST00000675663.1	CAST Ensembl NCBI GeneCards UniProt Show fit	calpastatin
chr3_+_142596385 Show fit	10.16	ENST00000457734.7 ENST00000483373.5 ENST00000475296.5 ENST00000495744.5 ENST00000476044.5 ENST00000461644.5 ENST00000464320.5	PLS1 Ensembl NCBI GeneCards UniProt Show fit	plastin 1
chr21_-_42315336 Show fit	9.86	ENST00000398431.2 ENST00000518498.3	TFF3 Ensembl NCBI GeneCards UniProt Show fit	trefoil factor 3
chr7_+_80602150 Show fit	9.67	ENST00000309881.11	CD36 Ensembl NCBI GeneCards UniProt Show fit	CD36 molecule
chr7_+_80602200 Show fit	9.61	ENST00000534394.5	CD36 Ensembl NCBI GeneCards UniProt Show fit	CD36 molecule
chr10_-_125160499 Show fit	9.58	ENST00000494626.6 ENST00000337195.9	CTBP2 Ensembl NCBI GeneCards UniProt Show fit	C-terminal binding protein 2
chr4_-_154612635 Show fit	9.32	ENST00000407946.5 ENST00000405164.5 ENST00000336098.8 ENST00000393846.6 ENST00000404648.7 ENST00000443553.5	FGG Ensembl NCBI GeneCards UniProt Show fit	fibrinogen gamma chain
chrX_-_20218941 Show fit	9.27	ENST00000457145.6	RPS6KA3 Ensembl NCBI GeneCards UniProt Show fit	ribosomal protein S6 kinase A3
chr5_+_102865805 Show fit	9.09	ENST00000346918.7	PAM Ensembl NCBI GeneCards UniProt Show fit	peptidylglycine alpha-amidating monooxygenase
chr3_-_146161167 Show fit	8.81	ENST00000360060.7 ENST00000282903.10	PLOD2 Ensembl NCBI GeneCards UniProt Show fit	procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
chr7_+_134891400 Show fit	8.81	ENST00000393118.6	CALD1 Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr7_+_134891566 Show fit	8.62	ENST00000424922.5 ENST00000495522.1	CALD1 Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chr21_-_26843012 Show fit	8.57	ENST00000517777.6	ADAMTS1 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase with thrombospondin type 1 motif 1
chr10_+_113709261 Show fit	8.55	ENST00000672138.1 ENST00000452490.3	CASP7 Ensembl NCBI GeneCards UniProt Show fit	caspase 7
chr10_+_102776237 Show fit	8.50	ENST00000369889.5	WBP1L Ensembl NCBI GeneCards UniProt Show fit	WW domain binding protein 1 like
chr3_+_186613052 Show fit	8.19	ENST00000411641.7 ENST00000273784.5	AHSG Ensembl NCBI GeneCards UniProt Show fit	alpha 2-HS glycoprotein
chr22_+_20774092 Show fit	8.18	ENST00000215727.10	SERPIND1 Ensembl NCBI GeneCards UniProt Show fit	serpin family D member 1
chr11_+_844406 Show fit	8.11	ENST00000397404.5	TSPAN4 Ensembl NCBI GeneCards UniProt Show fit	tetraspanin 4
chr11_-_6440980 Show fit	8.08	ENST00000265983.8 ENST00000615166.1	HPX Ensembl NCBI GeneCards UniProt Show fit	hemopexin
chr21_-_26843063 Show fit	8.08	ENST00000678221.1	ADAMTS1 Ensembl NCBI GeneCards UniProt Show fit	ADAM metallopeptidase with thrombospondin type 1 motif 1
chr10_+_122560751 Show fit	8.07	ENST00000338354.10 ENST00000664692.1 ENST00000653442.1 ENST00000664974.1	DMBT1 Ensembl NCBI GeneCards UniProt Show fit	deleted in malignant brain tumors 1
chr10_+_122560639 Show fit	8.05	ENST00000344338.7 ENST00000330163.8 ENST00000652446.2 ENST00000666315.1 ENST00000368955.7 ENST00000368909.7 ENST00000368956.6 ENST00000619379.1	DMBT1 Ensembl NCBI GeneCards UniProt Show fit	deleted in malignant brain tumors 1
chr12_-_55729660 Show fit	7.86	ENST00000546457.1 ENST00000549117.5	CD63 Ensembl NCBI GeneCards UniProt Show fit	CD63 molecule
chr10_+_122560679 Show fit	7.71	ENST00000657942.1	DMBT1 Ensembl NCBI GeneCards UniProt Show fit	deleted in malignant brain tumors 1
chr10_-_79560386 Show fit	7.59	ENST00000372327.9 ENST00000417041.1 ENST00000640627.1 ENST00000372325.7	SFTPA2 Ensembl NCBI GeneCards UniProt Show fit	surfactant protein A2
chr3_+_52211442 Show fit	7.48	ENST00000459884.1	ALAS1 Ensembl NCBI GeneCards UniProt Show fit	5'-aminolevulinate synthase 1
chr11_+_62419025 Show fit	7.39	ENST00000278282.3	SCGB1A1 Ensembl NCBI GeneCards UniProt Show fit	secretoglobin family 1A member 1
chr12_+_96194365 Show fit	7.32	ENST00000228741.8 ENST00000547249.1	ELK3 Ensembl NCBI GeneCards UniProt Show fit	ETS transcription factor ELK3
chr12_-_91178520 Show fit	7.29	ENST00000425043.5 ENST00000420120.6 ENST00000441303.6 ENST00000456569.2	DCN Ensembl NCBI GeneCards UniProt Show fit	decorin
chr10_-_125161019 Show fit	7.27	ENST00000411419.6	CTBP2 Ensembl NCBI GeneCards UniProt Show fit	C-terminal binding protein 2
chr17_-_19748355 Show fit	7.11	ENST00000494157.6	ALDH3A1 Ensembl NCBI GeneCards UniProt Show fit	aldehyde dehydrogenase 3 family member A1
chr19_+_16067526 Show fit	7.01	ENST00000646974.2	TPM4 Ensembl NCBI GeneCards UniProt Show fit	tropomyosin 4
chr14_-_37595224 Show fit	6.93	ENST00000250448.5	FOXA1 Ensembl NCBI GeneCards UniProt Show fit	forkhead box A1
chr12_-_120327762 Show fit	6.60	ENST00000308366.9 ENST00000423423.3	PLA2G1B Ensembl NCBI GeneCards UniProt Show fit	phospholipase A2 group IB
chr7_+_130266847 Show fit	6.57	ENST00000222481.9	CPA2 Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase A2
chr14_+_64504743 Show fit	6.51	ENST00000683701.1	ZBTB1 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 1
chr3_+_52777580 Show fit	6.31	ENST00000273283.7	ITIH1 Ensembl NCBI GeneCards UniProt Show fit	inter-alpha-trypsin inhibitor heavy chain 1
chr2_-_21044063 Show fit	6.25	ENST00000233242.5	APOB Ensembl NCBI GeneCards UniProt Show fit	apolipoprotein B
chr5_-_41213505 Show fit	5.99	ENST00000337836.10 ENST00000433294.1	C6 Ensembl NCBI GeneCards UniProt Show fit	complement C6
chr4_+_54229261 Show fit	5.62	ENST00000508170.5 ENST00000512143.1 ENST00000257290.10	PDGFRA Ensembl NCBI GeneCards UniProt Show fit	platelet derived growth factor receptor alpha
chr11_-_108593738 Show fit	5.58	ENST00000525344.5 ENST00000265843.9	EXPH5 Ensembl NCBI GeneCards UniProt Show fit	exophilin 5
chr3_+_148827800 Show fit	5.41	ENST00000282957.9 ENST00000468341.1	CPB1 Ensembl NCBI GeneCards UniProt Show fit	carboxypeptidase B1
chr10_-_46046264 Show fit	5.38	ENST00000581478.5 ENST00000582163.3	MSMB Ensembl NCBI GeneCards UniProt Show fit	microseminoprotein beta
chr1_-_93614091 Show fit	5.32	ENST00000370247.7	BCAR3 Ensembl NCBI GeneCards UniProt Show fit	BCAR3 adaptor protein, NSP family member
chr6_-_107824294 Show fit	5.31	ENST00000369020.8 ENST00000369022.6	SCML4 Ensembl NCBI GeneCards UniProt Show fit	Scm polycomb group protein like 4
chr9_-_86947496 Show fit	5.17	ENST00000298743.9	GAS1 Ensembl NCBI GeneCards UniProt Show fit	growth arrest specific 1
chr6_+_143608170 Show fit	5.04	ENST00000427704.6 ENST00000305766.10	PHACTR2 Ensembl NCBI GeneCards UniProt Show fit	phosphatase and actin regulator 2
chr17_-_17582417 Show fit	4.92	ENST00000395783.5	PEMT Ensembl NCBI GeneCards UniProt Show fit	phosphatidylethanolamine N-methyltransferase
chr5_+_32531786 Show fit	4.84	ENST00000512913.5	SUB1 Ensembl NCBI GeneCards UniProt Show fit	SUB1 regulator of transcription
chr10_+_122163672 Show fit	4.72	ENST00000369004.7 ENST00000260733.7	TACC2 Ensembl NCBI GeneCards UniProt Show fit	transforming acidic coiled-coil containing protein 2
chr5_+_180494430 Show fit	4.69	ENST00000393356.7 ENST00000618123.4	CNOT6 Ensembl NCBI GeneCards UniProt Show fit	CCR4-NOT transcription complex subunit 6
chr15_-_55249029 Show fit	4.59	ENST00000566877.5	RAB27A Ensembl NCBI GeneCards UniProt Show fit	RAB27A, member RAS oncogene family
chr12_+_10505890 Show fit	4.59	ENST00000538173.1	EIF2S3B Ensembl NCBI GeneCards UniProt Show fit	eukaryotic translation initiation factor 2 subunit gamma B
chr13_+_75760659 Show fit	4.53	ENST00000526202.5 ENST00000465261.6	LMO7 Ensembl NCBI GeneCards UniProt Show fit	LIM domain 7
chr10_+_122163590 Show fit	4.50	ENST00000368999.5	TACC2 Ensembl NCBI GeneCards UniProt Show fit	transforming acidic coiled-coil containing protein 2
chr1_-_94925759 Show fit	4.35	ENST00000415017.1 ENST00000545882.5	CNN3 Ensembl NCBI GeneCards UniProt Show fit	calponin 3
chr12_-_102478539 Show fit	4.34	ENST00000424202.6	IGF1 Ensembl NCBI GeneCards UniProt Show fit	insulin like growth factor 1
chr13_+_75760431 Show fit	4.21	ENST00000321797.12	LMO7 Ensembl NCBI GeneCards UniProt Show fit	LIM domain 7
chr14_-_36519679 Show fit	4.14	ENST00000498187.6	NKX2-1 Ensembl NCBI GeneCards UniProt Show fit	NK2 homeobox 1
chr4_-_69495897 Show fit	4.12	ENST00000305107.7 ENST00000639621.1	UGT2B4 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 2 member B4
chr1_-_56966133 Show fit	4.06	ENST00000535057.5 ENST00000543257.5	C8B Ensembl NCBI GeneCards UniProt Show fit	complement C8 beta chain
chr21_-_37072688 Show fit	3.96	ENST00000464265.5 ENST00000399102.5	PIGP Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol glycan anchor biosynthesis class P
chr4_-_69495861 Show fit	3.92	ENST00000512583.5	UGT2B4 Ensembl NCBI GeneCards UniProt Show fit	UDP glucuronosyltransferase family 2 member B4
chr4_-_185535498 Show fit	3.90	ENST00000284767.12 ENST00000284771.7 ENST00000284770.10 ENST00000620787.5 ENST00000629667.2	PDLIM3 Ensembl NCBI GeneCards UniProt Show fit	PDZ and LIM domain 3
chr19_-_45406327 Show fit	3.78	ENST00000593226.5 ENST00000418234.6	PPP1R13L Ensembl NCBI GeneCards UniProt Show fit	protein phosphatase 1 regulatory subunit 13 like
chr7_+_134745460 Show fit	3.76	ENST00000436461.6	CALD1 Ensembl NCBI GeneCards UniProt Show fit	caldesmon 1
chrX_+_136532205 Show fit	3.76	ENST00000370634.8	VGLL1 Ensembl NCBI GeneCards UniProt Show fit	vestigial like family member 1
chr3_+_138010143 Show fit	3.72	ENST00000183605.10	CLDN18 Ensembl NCBI GeneCards UniProt Show fit	claudin 18
chr4_-_110198650 Show fit	3.65	ENST00000394607.7	ELOVL6 Ensembl NCBI GeneCards UniProt Show fit	ELOVL fatty acid elongase 6
chr12_+_120978686 Show fit	3.64	ENST00000541395.5 ENST00000544413.2	HNF1A Ensembl NCBI GeneCards UniProt Show fit	HNF1 homeobox A
chr12_+_21372899 Show fit	3.64	ENST00000240652.8 ENST00000542023.1 ENST00000537593.1	IAPP Ensembl NCBI GeneCards UniProt Show fit	islet amyloid polypeptide
chr6_-_87095059 Show fit	3.58	ENST00000369582.6 ENST00000610310.3 ENST00000630630.2 ENST00000627148.3 ENST00000625577.1	CGA Ensembl NCBI GeneCards UniProt Show fit	glycoprotein hormones, alpha polypeptide
chr14_-_94323324 Show fit	3.58	ENST00000341584.4	SERPINA6 Ensembl NCBI GeneCards UniProt Show fit	serpin family A member 6
chr1_-_56966006 Show fit	3.55	ENST00000371237.9	C8B Ensembl NCBI GeneCards UniProt Show fit	complement C8 beta chain
chr14_-_36582593 Show fit	3.48	ENST00000258829.6	NKX2-8 Ensembl NCBI GeneCards UniProt Show fit	NK2 homeobox 8
chr17_-_47957824 Show fit	3.46	ENST00000300557.3	PRR15L Ensembl NCBI GeneCards UniProt Show fit	proline rich 15 like
chr11_-_102530738 Show fit	3.42	ENST00000260227.5	MMP7 Ensembl NCBI GeneCards UniProt Show fit	matrix metallopeptidase 7
chr7_+_95485898 Show fit	3.40	ENST00000428113.5	ASB4 Ensembl NCBI GeneCards UniProt Show fit	ankyrin repeat and SOCS box containing 4
chr7_-_100100716 Show fit	3.38	ENST00000354230.7 ENST00000425308.5	MCM7 Ensembl NCBI GeneCards UniProt Show fit	minichromosome maintenance complex component 7
chr5_+_180494344 Show fit	3.33	ENST00000261951.9	CNOT6 Ensembl NCBI GeneCards UniProt Show fit	CCR4-NOT transcription complex subunit 6
chr20_+_33235987 Show fit	3.21	ENST00000375422.6 ENST00000375413.8 ENST00000354297.9	BPIFA1 Ensembl NCBI GeneCards UniProt Show fit	BPI fold containing family A member 1
chr2_+_168901290 Show fit	3.13	ENST00000429379.2 ENST00000375363.8 ENST00000421979.1	G6PC2 Ensembl NCBI GeneCards UniProt Show fit	glucose-6-phosphatase catalytic subunit 2
chr3_-_114179052 Show fit	3.04	ENST00000383673.5 ENST00000295881.9	DRD3 Ensembl NCBI GeneCards UniProt Show fit	dopamine receptor D3
chr3_+_137998735 Show fit	2.97	ENST00000343735.8	CLDN18 Ensembl NCBI GeneCards UniProt Show fit	claudin 18
chr7_+_112423137 Show fit	2.93	ENST00000005558.8 ENST00000621379.4	IFRD1 Ensembl NCBI GeneCards UniProt Show fit	interferon related developmental regulator 1
chr1_-_244860376 Show fit	2.88	ENST00000638716.1	HNRNPU Ensembl NCBI GeneCards UniProt Show fit	heterogeneous nuclear ribonucleoprotein U
chr4_+_146175702 Show fit	2.77	ENST00000296581.11 ENST00000649747.1 ENST00000502781.5	LSM6 Ensembl NCBI GeneCards UniProt Show fit	LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
chr18_+_68798065 Show fit	2.65	ENST00000360242.9	CCDC102B Ensembl NCBI GeneCards UniProt Show fit	coiled-coil domain containing 102B
chr1_+_200027605 Show fit	2.64	ENST00000236914.7	NR5A2 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 5 group A member 2
chr5_-_138338325 Show fit	2.61	ENST00000510119.1 ENST00000513970.5	CDC25C Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 25C
chr10_-_79949098 Show fit	2.53	ENST00000372292.8	SFTPD Ensembl NCBI GeneCards UniProt Show fit	surfactant protein D
chr6_-_41747390 Show fit	2.52	ENST00000356667.8 ENST00000373025.7 ENST00000425343.6	PGC Ensembl NCBI GeneCards UniProt Show fit	progastricsin
chr8_+_32646838 Show fit	2.52	ENST00000651333.1 ENST00000652592.1	NRG1 Ensembl NCBI GeneCards UniProt Show fit	neuregulin 1
chr1_-_203351115 Show fit	2.50	ENST00000354955.5	FMOD Ensembl NCBI GeneCards UniProt Show fit	fibromodulin
chr8_+_32647080 Show fit	2.49	ENST00000520502.7 ENST00000523041.2 ENST00000650819.1	NRG1 Ensembl NCBI GeneCards UniProt Show fit	neuregulin 1
chr3_+_141387801 Show fit	2.48	ENST00000514251.5	ZBTB38 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 38
chr11_-_10568650 Show fit	2.46	ENST00000256178.8	LYVE1 Ensembl NCBI GeneCards UniProt Show fit	lymphatic vessel endothelial hyaluronan receptor 1
chr20_-_7940444 Show fit	2.46	ENST00000378789.4	HAO1 Ensembl NCBI GeneCards UniProt Show fit	hydroxyacid oxidase 1
chr12_-_48004467 Show fit	2.45	ENST00000380518.8	COL2A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type II alpha 1 chain
chr7_+_28412511 Show fit	2.42	ENST00000357727.7	CREB5 Ensembl NCBI GeneCards UniProt Show fit	cAMP responsive element binding protein 5
chr9_-_92424427 Show fit	2.41	ENST00000375550.5	OMD Ensembl NCBI GeneCards UniProt Show fit	osteomodulin
chr8_+_69492793 Show fit	2.29	ENST00000616868.1 ENST00000419716.7 ENST00000402687.9	SULF1 Ensembl NCBI GeneCards UniProt Show fit	sulfatase 1
chr11_+_121102666 Show fit	2.29	ENST00000264037.2	TECTA Ensembl NCBI GeneCards UniProt Show fit	tectorin alpha
chr22_-_21227637 Show fit	2.27	ENST00000401924.5	GGT2 Ensembl NCBI GeneCards UniProt Show fit	gamma-glutamyltransferase 2
chr7_+_77840122 Show fit	2.27	ENST00000450574.5 ENST00000248550.7	PHTF2 Ensembl NCBI GeneCards UniProt Show fit	putative homeodomain transcription factor 2
chr17_+_9021501 Show fit	2.20	ENST00000173229.7	NTN1 Ensembl NCBI GeneCards UniProt Show fit	netrin 1
chr12_-_48004496 Show fit	2.17	ENST00000337299.7	COL2A1 Ensembl NCBI GeneCards UniProt Show fit	collagen type II alpha 1 chain
chr6_+_160702238 Show fit	2.14	ENST00000366924.6 ENST00000308192.14 ENST00000418964.1	PLG Ensembl NCBI GeneCards UniProt Show fit	plasminogen
chr13_+_77535669 Show fit	2.09	ENST00000535157.5	SCEL Ensembl NCBI GeneCards UniProt Show fit	sciellin
chr13_+_77535681 Show fit	2.09	ENST00000349847.4	SCEL Ensembl NCBI GeneCards UniProt Show fit	sciellin
chr17_+_76376581 Show fit	2.08	ENST00000591651.5 ENST00000545180.5	SPHK1 Ensembl NCBI GeneCards UniProt Show fit	sphingosine kinase 1
chr10_+_101131284 Show fit	2.07	ENST00000370196.11 ENST00000467928.2	TLX1 Ensembl NCBI GeneCards UniProt Show fit	T cell leukemia homeobox 1
chr1_-_116667668 Show fit	2.07	ENST00000369486.8 ENST00000369483.5	IGSF3 Ensembl NCBI GeneCards UniProt Show fit	immunoglobulin superfamily member 3
chr13_+_77535742 Show fit	2.00	ENST00000377246.7	SCEL Ensembl NCBI GeneCards UniProt Show fit	sciellin
chr9_+_27109200 Show fit	1.98	ENST00000380036.10	TEK Ensembl NCBI GeneCards UniProt Show fit	TEK receptor tyrosine kinase
chr11_+_59787067 Show fit	1.92	ENST00000528805.1	STX3 Ensembl NCBI GeneCards UniProt Show fit	syntaxin 3
chr1_-_216423396 Show fit	1.89	ENST00000366942.3 ENST00000674083.1 ENST00000307340.8	USH2A Ensembl NCBI GeneCards UniProt Show fit	usherin
chr16_-_48610150 Show fit	1.88	ENST00000262384.4	N4BP1 Ensembl NCBI GeneCards UniProt Show fit	NEDD4 binding protein 1
chr4_-_110198579 Show fit	1.87	ENST00000302274.8	ELOVL6 Ensembl NCBI GeneCards UniProt Show fit	ELOVL fatty acid elongase 6
chr3_+_69936583 Show fit	1.84	ENST00000314557.10 ENST00000394351.9	MITF Ensembl NCBI GeneCards UniProt Show fit	melanocyte inducing transcription factor
chr15_-_29822418 Show fit	1.82	ENST00000614355.5 ENST00000495972.6 ENST00000346128.10	TJP1 Ensembl NCBI GeneCards UniProt Show fit	tight junction protein 1
chrX_+_100584928 Show fit	1.82	ENST00000373031.5	TNMD Ensembl NCBI GeneCards UniProt Show fit	tenomodulin
chr1_+_74235377 Show fit	1.80	ENST00000326637.8	TNNI3K Ensembl NCBI GeneCards UniProt Show fit	TNNI3 interacting kinase
chr9_+_27109135 Show fit	1.75	ENST00000519097.5 ENST00000615002.4	TEK Ensembl NCBI GeneCards UniProt Show fit	TEK receptor tyrosine kinase
chr7_+_48924559 Show fit	1.72	ENST00000650262.1	CDC14C Ensembl NCBI GeneCards UniProt Show fit	cell division cycle 14C
chr1_-_246566238 Show fit	1.70	ENST00000366514.5	TFB2M Ensembl NCBI GeneCards UniProt Show fit	transcription factor B2, mitochondrial
chr5_-_136365476 Show fit	1.68	ENST00000378459.7 ENST00000502753.4 ENST00000513104.6 ENST00000352189.8	TRPC7 Ensembl NCBI GeneCards UniProt Show fit	transient receptor potential cation channel subfamily C member 7
chr2_+_28395511 Show fit	1.63	ENST00000436647.1	FOSL2 Ensembl NCBI GeneCards UniProt Show fit	FOS like 2, AP-1 transcription factor subunit
chr6_-_42048648 Show fit	1.61	ENST00000502771.1 ENST00000508143.5 ENST00000514588.1 ENST00000510503.5	CCND3 Ensembl NCBI GeneCards UniProt Show fit	cyclin D3
chr7_+_135148041 Show fit	1.59	ENST00000275767.3	TMEM140 Ensembl NCBI GeneCards UniProt Show fit	transmembrane protein 140
chr5_+_96936071 Show fit	1.55	ENST00000231368.10	LNPEP Ensembl NCBI GeneCards UniProt Show fit	leucyl and cystinyl aminopeptidase
chr11_+_1157946 Show fit	1.53	ENST00000621226.2	MUC5AC Ensembl NCBI GeneCards UniProt Show fit	mucin 5AC, oligomeric mucus/gel-forming
chr1_+_152514474 Show fit	1.51	ENST00000368790.4	CRCT1 Ensembl NCBI GeneCards UniProt Show fit	cysteine rich C-terminal 1
chr14_+_64503943 Show fit	1.50	ENST00000556965.1 ENST00000554015.5	ZBTB1 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 1
chr1_+_200027702 Show fit	1.49	ENST00000367362.8	NR5A2 Ensembl NCBI GeneCards UniProt Show fit	nuclear receptor subfamily 5 group A member 2
chr1_+_116111395 Show fit	1.48	ENST00000684484.1 ENST00000369500.4	MAB21L3 Ensembl NCBI GeneCards UniProt Show fit	mab-21 like 3
chr5_+_148394712 Show fit	1.46	ENST00000513826.1	FBXO38 Ensembl NCBI GeneCards UniProt Show fit	F-box protein 38
chr7_-_81770039 Show fit	1.43	ENST00000222390.11 ENST00000453411.6 ENST00000457544.7 ENST00000444829.7	HGF Ensembl NCBI GeneCards UniProt Show fit	hepatocyte growth factor
chr9_+_79572572 Show fit	1.36	ENST00000435650.5 ENST00000414465.5 ENST00000376537.8	TLE4 Ensembl NCBI GeneCards UniProt Show fit	TLE family member 4, transcriptional corepressor
chr21_-_14658812 Show fit	1.36	ENST00000647101.1	SAMSN1 Ensembl NCBI GeneCards UniProt Show fit	SAM domain, SH3 domain and nuclear localization signals 1
chr12_-_14696571 Show fit	1.30	ENST00000261170.5	GUCY2C Ensembl NCBI GeneCards UniProt Show fit	guanylate cyclase 2C
chrX_-_15384402 Show fit	1.26	ENST00000297904.4	VEGFD Ensembl NCBI GeneCards UniProt Show fit	vascular endothelial growth factor D
chr2_+_151409878 Show fit	1.24	ENST00000453091.6 ENST00000428287.6 ENST00000444746.7 ENST00000243326.9 ENST00000414861.6	RIF1 Ensembl NCBI GeneCards UniProt Show fit	replication timing regulatory factor 1
chr7_+_117014881 Show fit	1.16	ENST00000422922.5 ENST00000432298.5	ST7 Ensembl NCBI GeneCards UniProt Show fit	suppression of tumorigenicity 7
chr13_-_48413105 Show fit	1.15	ENST00000620633.5	LPAR6 Ensembl NCBI GeneCards UniProt Show fit	lysophosphatidic acid receptor 6
chr4_+_186227501 Show fit	1.14	ENST00000446598.6 ENST00000264690.11 ENST00000513864.2	KLKB1 Ensembl NCBI GeneCards UniProt Show fit	kallikrein B1
chr2_-_171160833 Show fit	1.14	ENST00000360843.7 ENST00000431350.7	TLK1 Ensembl NCBI GeneCards UniProt Show fit	tousled like kinase 1
chr3_+_148730100 Show fit	1.12	ENST00000474935.5 ENST00000475347.5 ENST00000461609.1	AGTR1 Ensembl NCBI GeneCards UniProt Show fit	angiotensin II receptor type 1
chr20_+_64164566 Show fit	1.11	ENST00000650655.1	MYT1 Ensembl NCBI GeneCards UniProt Show fit	myelin transcription factor 1
chr12_+_120978537 Show fit	1.06	ENST00000257555.11 ENST00000400024.6	HNF1A Ensembl NCBI GeneCards UniProt Show fit	HNF1 homeobox A
chr12_+_103587266 Show fit	1.04	ENST00000388887.7	STAB2 Ensembl NCBI GeneCards UniProt Show fit	stabilin 2
chr8_+_132866948 Show fit	1.04	ENST00000220616.9	TG Ensembl NCBI GeneCards UniProt Show fit	thyroglobulin
chr8_+_11809135 Show fit	1.03	ENST00000528643.5 ENST00000525777.5	FDFT1 Ensembl NCBI GeneCards UniProt Show fit	farnesyl-diphosphate farnesyltransferase 1
chr20_+_64164446 Show fit	0.99	ENST00000328439.6	MYT1 Ensembl NCBI GeneCards UniProt Show fit	myelin transcription factor 1
chr6_+_52420992 Show fit	0.99	ENST00000636954.1 ENST00000636566.1 ENST00000638075.1	EFHC1 Ensembl NCBI GeneCards UniProt Show fit	EF-hand domain containing 1
chr8_+_76681208 Show fit	0.93	ENST00000651372.2	ZFHX4 Ensembl NCBI GeneCards UniProt Show fit	zinc finger homeobox 4
chr2_-_213151590 Show fit	0.92	ENST00000374319.8 ENST00000457361.5 ENST00000451136.6 ENST00000434687.6	IKZF2 Ensembl NCBI GeneCards UniProt Show fit	IKAROS family zinc finger 2
chr2_-_49154507 Show fit	0.87	ENST00000406846.7	FSHR Ensembl NCBI GeneCards UniProt Show fit	follicle stimulating hormone receptor
chr20_+_64164474 Show fit	0.86	ENST00000622439.4 ENST00000536311.5	MYT1 Ensembl NCBI GeneCards UniProt Show fit	myelin transcription factor 1
chr9_+_79572715 Show fit	0.84	ENST00000265284.10	TLE4 Ensembl NCBI GeneCards UniProt Show fit	TLE family member 4, transcriptional corepressor
chr17_+_69414690 Show fit	0.81	ENST00000590474.7	MAP2K6 Ensembl NCBI GeneCards UniProt Show fit	mitogen-activated protein kinase kinase 6
chr5_-_128339191 Show fit	0.81	ENST00000507835.5	FBN2 Ensembl NCBI GeneCards UniProt Show fit	fibrillin 2
chr6_-_160664270 Show fit	0.72	ENST00000316300.10	LPA Ensembl NCBI GeneCards UniProt Show fit	lipoprotein(a)
chrX_-_24647091 Show fit	0.72	ENST00000356768.8	PCYT1B Ensembl NCBI GeneCards UniProt Show fit	phosphate cytidylyltransferase 1, choline, beta
chr2_+_47403061 Show fit	0.71	ENST00000543555.6	MSH2 Ensembl NCBI GeneCards UniProt Show fit	mutS homolog 2
chrX_+_136648138 Show fit	0.70	ENST00000370629.7	CD40LG Ensembl NCBI GeneCards UniProt Show fit	CD40 ligand
chr14_+_36661852 Show fit	0.70	ENST00000361487.7	PAX9 Ensembl NCBI GeneCards UniProt Show fit	paired box 9
chr10_+_116590956 Show fit	0.70	ENST00000358834.9 ENST00000528052.5	PNLIPRP1 Ensembl NCBI GeneCards UniProt Show fit	pancreatic lipase related protein 1
chr3_+_160677152 Show fit	0.67	ENST00000320767.4	ARL14 Ensembl NCBI GeneCards UniProt Show fit	ADP ribosylation factor like GTPase 14
chr3_+_189631373 Show fit	0.67	ENST00000264731.8 ENST00000418709.6 ENST00000320472.9 ENST00000392460.7 ENST00000440651.6	TP63 Ensembl NCBI GeneCards UniProt Show fit	tumor protein p63
chr3_+_69936629 Show fit	0.67	ENST00000394348.2 ENST00000531774.1	MITF Ensembl NCBI GeneCards UniProt Show fit	melanocyte inducing transcription factor
chr2_-_49154433 Show fit	0.65	ENST00000454032.5 ENST00000304421.8	FSHR Ensembl NCBI GeneCards UniProt Show fit	follicle stimulating hormone receptor
chr6_-_89217339 Show fit	0.60	ENST00000454853.7	GABRR1 Ensembl NCBI GeneCards UniProt Show fit	gamma-aminobutyric acid type A receptor subunit rho1
chr14_-_64504570 Show fit	0.59	ENST00000394715.1	ZBTB25 Ensembl NCBI GeneCards UniProt Show fit	zinc finger and BTB domain containing 25
chr7_+_106865263 Show fit	0.56	ENST00000440650.6 ENST00000496166.6 ENST00000473541.5	PIK3CG Ensembl NCBI GeneCards UniProt Show fit	phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
chr19_-_18791297 Show fit	0.55	ENST00000542601.6 ENST00000222271.7 ENST00000425807.1	COMP Ensembl NCBI GeneCards UniProt Show fit	cartilage oligomeric matrix protein
chrX_+_1268807 Show fit	0.55	ENST00000381524.8 ENST00000381529.9 ENST00000412290.6	CSF2RA Ensembl NCBI GeneCards UniProt Show fit	colony stimulating factor 2 receptor subunit alpha
chr2_+_203936755 Show fit	0.53	ENST00000316386.11 ENST00000435193.1	ICOS Ensembl NCBI GeneCards UniProt Show fit	inducible T cell costimulator
chr12_-_52434363 Show fit	0.53	ENST00000252245.6	KRT75 Ensembl NCBI GeneCards UniProt Show fit	keratin 75
chr9_-_20622479 Show fit	0.51	ENST00000380338.9	MLLT3 Ensembl NCBI GeneCards UniProt Show fit	MLLT3 super elongation complex subunit
chr17_-_50468871 Show fit	0.51	ENST00000508540.6 ENST00000258969.4	CHAD Ensembl NCBI GeneCards UniProt Show fit	chondroadherin
chr2_+_70935919 Show fit	0.44	ENST00000412314.5	ATP6V1B1 Ensembl NCBI GeneCards UniProt Show fit	ATPase H+ transporting V1 subunit B1
chrX_+_16946862 Show fit	0.43	ENST00000303843.7	REPS2 Ensembl NCBI GeneCards UniProt Show fit	RALBP1 associated Eps domain containing 2
chr7_+_30963945 Show fit	0.43	ENST00000326139.7	GHRHR Ensembl NCBI GeneCards UniProt Show fit	growth hormone releasing hormone receptor

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.4	29.6	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
3.8	11.5	GO:0045645	regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645)
2.9	11.7	GO:0009956	radial pattern formation(GO:0009956)
2.7	8.0	GO:0006711	estrogen catabolic process(GO:0006711)
2.6	7.9	GO:2000176	regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
2.4	26.4	GO:0043152	induction of bacterial agglutination(GO:0043152)
2.4	4.7	GO:0035565	regulation of pronephros size(GO:0035565)
2.3	9.1	GO:0031179	peptide amidation(GO:0001519) protein amidation(GO:0018032) peptide modification(GO:0031179)
2.2	8.8	GO:0046947	hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
2.1	19.3	GO:2000334	response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
2.0	10.2	GO:1902896	terminal web assembly(GO:1902896)
2.0	8.1	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
2.0	8.0	GO:2000327	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
1.9	5.6	GO:0072277	platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
1.7	6.9	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) prostate gland stromal morphogenesis(GO:0060741) epithelial cell maturation involved in prostate gland development(GO:0060743)
1.7	16.8	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
1.6	6.6	GO:0044240	multicellular organism lipid catabolic process(GO:0044240)
1.5	6.0	GO:0045917	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
1.5	7.4	GO:0010193	response to ozone(GO:0010193)
1.4	8.2	GO:0008218	bioluminescence(GO:0008218)
1.4	12.2	GO:0060574	intestinal epithelial cell maturation(GO:0060574)
1.3	12.8	GO:0006621	protein retention in ER lumen(GO:0006621)
1.3	45.9	GO:0060706	cell differentiation involved in embryonic placenta development(GO:0060706)
1.1	8.5	GO:0072734	response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
1.0	4.1	GO:0021759	globus pallidus development(GO:0021759)
1.0	2.9	GO:0007518	myoblast fate determination(GO:0007518)
0.9	21.7	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.9	15.8	GO:0001542	ovulation from ovarian follicle(GO:0001542)
0.9	6.2	GO:0006642	triglyceride mobilization(GO:0006642)
0.9	4.3	GO:1904073	regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.8	6.7	GO:0071847	TNFSF11-mediated signaling pathway(GO:0071847)
0.8	2.5	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.8	4.1	GO:0061113	pancreas morphogenesis(GO:0061113)
0.8	2.5	GO:0009441	glycolate metabolic process(GO:0009441)
0.8	3.2	GO:0044010	biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.8	3.2	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.8	22.4	GO:1901741	positive regulation of myoblast fusion(GO:1901741)
0.8	4.6	GO:1903435	positive regulation of constitutive secretory pathway(GO:1903435)
0.8	3.0	GO:0035483	negative regulation of sodium:proton antiporter activity(GO:0032416) gastric motility(GO:0035482) gastric emptying(GO:0035483) musculoskeletal movement, spinal reflex action(GO:0050883)
0.7	2.1	GO:0046521	sphingoid catabolic process(GO:0046521)
0.7	5.5	GO:0034626	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.7	42.0	GO:0030195	negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.6	4.9	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.6	7.3	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.6	1.7	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.6	7.9	GO:0035826	rubidium ion transport(GO:0035826) regulation of rubidium ion transport(GO:2000680)
0.5	5.6	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.5	0.5	GO:1900154	regulation of bone trabecula formation(GO:1900154) negative regulation of bone trabecula formation(GO:1900155)
0.5	1.5	GO:0001545	primary ovarian follicle growth(GO:0001545)
0.5	1.9	GO:0048496	maintenance of organ identity(GO:0048496)
0.5	3.7	GO:0048014	Tie signaling pathway(GO:0048014)
0.4	2.5	GO:0002225	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.4	5.0	GO:0021840	directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.4	7.5	GO:0006782	protoporphyrinogen IX biosynthetic process(GO:0006782)
0.4	11.8	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.4	7.6	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.4	1.1	GO:0006311	meiotic gene conversion(GO:0006311) regulation of reciprocal meiotic recombination(GO:0010520)
0.4	2.2	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.4	1.8	GO:1901350	cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.4	1.8	GO:0035992	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.4	3.6	GO:0097646	calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.3	6.6	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
0.3	5.2	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.3	8.2	GO:0030502	negative regulation of bone mineralization(GO:0030502)
0.3	3.4	GO:2001214	positive regulation of vasculogenesis(GO:2001214)
0.3	1.2	GO:2001034	positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.3	2.1	GO:0032808	lacrimal gland development(GO:0032808)
0.3	4.6	GO:0060174	limb bud formation(GO:0060174)
0.3	1.1	GO:0086097	phospholipase C-activating angiotensin-activated signaling pathway(GO:0086097)
0.3	9.3	GO:0043555	regulation of translation in response to stress(GO:0043555)
0.3	1.9	GO:0098967	exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.3	0.8	GO:0072709	cellular response to sorbitol(GO:0072709)
0.3	3.1	GO:0051156	glucose 6-phosphate metabolic process(GO:0051156)
0.3	3.4	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.2	1.5	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.2	31.9	GO:0002062	chondrocyte differentiation(GO:0002062)
0.2	5.3	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.2	4.4	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.2	3.8	GO:0003215	cardiac right ventricle morphogenesis(GO:0003215)
0.2	2.9	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.2	2.4	GO:0042340	keratan sulfate catabolic process(GO:0042340)
0.2	4.0	GO:0016254	preassembly of GPI anchor in ER membrane(GO:0016254)
0.2	0.9	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
0.2	7.3	GO:2000144	positive regulation of DNA-templated transcription, initiation(GO:2000144)
0.2	2.3	GO:1901750	leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.2	9.8	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.2	1.0	GO:0006696	ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.2	0.7	GO:0007499	ectoderm and mesoderm interaction(GO:0007499) squamous basal epithelial stem cell differentiation involved in prostate gland acinus development(GO:0060529)
0.2	1.6	GO:0002480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.1	0.4	GO:0046010	positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.1	1.3	GO:0060754	positive regulation of mast cell chemotaxis(GO:0060754)
0.1	3.4	GO:0044849	estrous cycle(GO:0044849)
0.1	1.3	GO:0007168	receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1	1.0	GO:0015705	iodide transport(GO:0015705)
0.1	0.8	GO:0035583	sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.1	0.4	GO:0010966	regulation of phosphate transport(GO:0010966)
0.1	3.6	GO:0008211	glucocorticoid metabolic process(GO:0008211)
0.1	1.7	GO:0051256	mitotic spindle midzone assembly(GO:0051256)
0.1	1.8	GO:0086069	bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.1	1.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.1	7.6	GO:0007585	respiratory gaseous exchange(GO:0007585)
0.1	7.0	GO:0030049	muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275)
0.1	2.6	GO:1902751	positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1	1.7	GO:0006828	manganese ion transport(GO:0006828)
0.1	7.1	GO:0006081	cellular aldehyde metabolic process(GO:0006081)
0.1	2.8	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.1	0.7	GO:0006657	CDP-choline pathway(GO:0006657)
0.1	3.6	GO:0016486	peptide hormone processing(GO:0016486)
0.1	10.2	GO:0021987	cerebral cortex development(GO:0021987)
0.1	0.3	GO:0019532	oxalate transport(GO:0019532)
0.1	0.7	GO:2000353	positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.9	GO:0042481	regulation of odontogenesis(GO:0042481)
0.0	0.5	GO:0007379	segment specification(GO:0007379)
0.0	1.6	GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0	0.7	GO:0034374	low-density lipoprotein particle remodeling(GO:0034374)
0.0	23.1	GO:0042493	response to drug(GO:0042493)
0.0	1.6	GO:0048146	positive regulation of fibroblast proliferation(GO:0048146)
0.0	5.2	GO:0002576	platelet degranulation(GO:0002576)
0.0	3.5	GO:0050680	negative regulation of epithelial cell proliferation(GO:0050680)
0.0	4.0	GO:0007586	digestion(GO:0007586)
0.0	15.1	GO:0006936	muscle contraction(GO:0006936)
0.0	0.5	GO:0002517	T cell tolerance induction(GO:0002517)
0.0	1.4	GO:0050869	negative regulation of B cell activation(GO:0050869)
0.0	1.9	GO:0034644	cellular response to UV(GO:0034644)
0.0	2.3	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.0	0.4	GO:1900017	positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0	0.7	GO:0015991	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991)
0.0	4.3	GO:0030216	keratinocyte differentiation(GO:0030216)
0.0	7.8	GO:0043687	post-translational protein modification(GO:0043687)
0.0	1.0	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.4	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.0	2.4	GO:0006275	regulation of DNA replication(GO:0006275)
0.0	0.3	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.1	GO:0043129	surfactant homeostasis(GO:0043129)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.5	45.0	GO:1990357	terminal web(GO:1990357)
2.4	12.2	GO:0070557	PCNA-p21 complex(GO:0070557)
1.7	13.6	GO:0005579	membrane attack complex(GO:0005579)
1.5	16.8	GO:0097470	ribbon synapse(GO:0097470)
1.4	21.2	GO:0030478	actin cap(GO:0030478)
1.3	24.5	GO:0042589	zymogen granule membrane(GO:0042589)
0.9	6.2	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.9	12.8	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.8	25.2	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.8	9.3	GO:0005577	fibrinogen complex(GO:0005577)
0.7	24.3	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.7	7.9	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.6	4.3	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.6	7.3	GO:0098647	collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.5	1.5	GO:0070701	mucus layer(GO:0070701)
0.5	7.0	GO:0005862	muscle thin filament tropomyosin(GO:0005862)
0.5	1.9	GO:0002139	stereocilia coupling link(GO:0002139) periciliary membrane compartment(GO:1990075)
0.5	10.1	GO:0042599	lamellar body(GO:0042599)
0.4	3.4	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.4	8.0	GO:0030014	CCR4-NOT complex(GO:0030014)
0.4	4.6	GO:0032585	multivesicular body membrane(GO:0032585)
0.4	4.0	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.4	49.2	GO:0005604	basement membrane(GO:0005604)
0.4	2.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.4	8.1	GO:0071682	endocytic vesicle lumen(GO:0071682)
0.3	1.6	GO:0031905	early endosome lumen(GO:0031905)
0.3	0.9	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.3	8.8	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.3	3.4	GO:0042555	MCM complex(GO:0042555)
0.2	1.1	GO:0032302	MutSalpha complex(GO:0032301) MutSbeta complex(GO:0032302)
0.2	2.8	GO:0005688	U6 snRNP(GO:0005688)
0.2	1.2	GO:0001940	male pronucleus(GO:0001940)
0.1	6.2	GO:0001533	cornified envelope(GO:0001533)
0.1	5.2	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.1	2.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.1	11.1	GO:0031093	platelet alpha granule lumen(GO:0031093)
0.1	5.0	GO:0030673	axolemma(GO:0030673)
0.1	3.7	GO:0009925	basal plasma membrane(GO:0009925)
0.1	6.2	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	8.5	GO:0005796	Golgi lumen(GO:0005796)
0.1	1.3	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.1	5.2	GO:0031526	brush border membrane(GO:0031526)
0.1	9.1	GO:0072562	blood microparticle(GO:0072562)
0.1	3.8	GO:0045171	intercellular bridge(GO:0045171)
0.1	0.7	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1	60.3	GO:0009986	cell surface(GO:0009986)
0.1	1.8	GO:0005921	gap junction(GO:0005921)
0.1	8.7	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.1	7.0	GO:0000151	ubiquitin ligase complex(GO:0000151)
0.0	2.5	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	5.2	GO:0005923	bicellular tight junction(GO:0005923)
0.0	4.4	GO:0005913	cell-cell adherens junction(GO:0005913)
0.0	6.9	GO:0001650	fibrillar center(GO:0001650)
0.0	40.4	GO:0005615	extracellular space(GO:0005615)
0.0	1.7	GO:0005801	cis-Golgi network(GO:0005801)
0.0	1.7	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	1.6	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	2.3	GO:0031225	anchored component of membrane(GO:0031225)
0.0	2.8	GO:0072686	mitotic spindle(GO:0072686)
0.0	3.9	GO:0030018	Z disc(GO:0030018)
0.0	94.6	GO:0005654	nucleoplasm(GO:0005654)
0.0	0.5	GO:0045095	keratin filament(GO:0045095)
0.0	21.3	GO:0005783	endoplasmic reticulum(GO:0005783)
0.0	1.4	GO:0001726	ruffle(GO:0001726)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
7.9	23.8	GO:0035375	zymogen binding(GO:0035375)
4.3	12.8	GO:0005046	KDEL sequence binding(GO:0005046)
2.4	12.2	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
2.4	19.3	GO:0070892	lipoteichoic acid receptor activity(GO:0070892)
2.4	16.8	GO:0016618	hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
2.3	9.1	GO:0004598	peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
2.2	8.8	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
2.2	21.7	GO:0010859	calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
2.0	29.6	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
1.9	5.6	GO:0005017	platelet-derived growth factor-activated receptor activity(GO:0005017)
1.6	4.9	GO:0004608	phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
1.6	6.2	GO:0035473	lipase binding(GO:0035473)
1.5	7.5	GO:0003870	5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
1.5	7.4	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
1.3	5.3	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
1.2	7.1	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
1.0	3.1	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
1.0	8.1	GO:0015232	heme transporter activity(GO:0015232)
0.9	27.9	GO:0070410	co-SMAD binding(GO:0070410)
0.8	2.5	GO:0052853	(S)-2-hydroxy-acid oxidase activity(GO:0003973) very-long-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052852) long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity(GO:0052853) medium-chain-(S)-2-hydroxy-acid oxidase activity(GO:0052854)
0.8	21.2	GO:0005523	tropomyosin binding(GO:0005523)
0.7	11.5	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
0.7	5.5	GO:0102336	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.7	6.6	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.7	4.6	GO:0042289	MHC class II protein binding(GO:0042289)
0.6	2.3	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.5	19.8	GO:0001972	retinoic acid binding(GO:0001972)
0.5	1.5	GO:0004963	follicle-stimulating hormone receptor activity(GO:0004963)
0.4	8.0	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.4	45.8	GO:0008307	structural constituent of muscle(GO:0008307)
0.4	4.0	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.4	3.0	GO:0001591	dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.4	36.9	GO:0050840	extracellular matrix binding(GO:0050840)
0.4	1.1	GO:0001596	angiotensin type I receptor activity(GO:0001596)
0.3	20.0	GO:0005160	transforming growth factor beta receptor binding(GO:0005160)
0.3	7.9	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.3	9.2	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.3	1.8	GO:0031013	troponin I binding(GO:0031013)
0.3	2.1	GO:0017050	sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.3	8.5	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.3	1.7	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.3	5.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176) transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.3	2.1	GO:1990405	protein antigen binding(GO:1990405)
0.3	4.1	GO:0044213	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.2	0.7	GO:0005174	CD40 receptor binding(GO:0005174)
0.2	1.1	GO:0032181	double-strand/single-strand DNA junction binding(GO:0000406) single thymine insertion binding(GO:0032143) dinucleotide repeat insertion binding(GO:0032181)
0.2	17.5	GO:0004869	cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.2	31.9	GO:0005178	integrin binding(GO:0005178)
0.2	1.7	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.2	18.1	GO:0004867	serine-type endopeptidase inhibitor activity(GO:0004867)
0.2	1.3	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.2	4.6	GO:0031489	myosin V binding(GO:0031489)
0.2	2.3	GO:0036374	glutathione hydrolase activity(GO:0036374)
0.2	4.4	GO:0098641	cadherin binding involved in cell-cell adhesion(GO:0098641)
0.2	1.0	GO:0051996	farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.2	18.3	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.2	0.8	GO:0030023	extracellular matrix constituent conferring elasticity(GO:0030023)
0.2	13.4	GO:0097110	scaffold protein binding(GO:0097110)
0.1	0.7	GO:0004105	choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1	1.9	GO:0050542	icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.1	2.5	GO:0008327	methyl-CpG binding(GO:0008327)
0.1	0.4	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.1	1.1	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.1	5.0	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.1	2.9	GO:0070034	telomerase RNA binding(GO:0070034)
0.1	3.5	GO:0005540	hyaluronic acid binding(GO:0005540)
0.1	0.9	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1	2.5	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.1	1.3	GO:0015643	guanylate cyclase activity(GO:0004383) toxic substance binding(GO:0015643)
0.1	1.6	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.1	0.3	GO:0050659	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1	3.3	GO:0050699	WW domain binding(GO:0050699)
0.1	4.4	GO:0005201	extracellular matrix structural constituent(GO:0005201)
0.1	3.4	GO:0004003	ATP-dependent DNA helicase activity(GO:0004003)
0.1	13.9	GO:0030674	protein binding, bridging(GO:0030674)
0.1	0.7	GO:0001968	fibronectin binding(GO:0001968)
0.1	9.5	GO:0005200	structural constituent of cytoskeleton(GO:0005200)
0.1	3.6	GO:0001540	beta-amyloid binding(GO:0001540)
0.1	9.1	GO:0035257	nuclear hormone receptor binding(GO:0035257)
0.0	4.2	GO:0004714	transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0	1.9	GO:0005518	collagen binding(GO:0005518)
0.0	1.4	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	4.1	GO:0098531	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0	0.3	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.0	2.0	GO:0046934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0	1.7	GO:0008138	protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0	0.3	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	4.8	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	1.6	GO:0004693	cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0	0.7	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.8	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	6.8	GO:0001077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0	3.8	GO:0003713	transcription coactivator activity(GO:0003713)
0.0	6.3	GO:0004842	ubiquitin-protein transferase activity(GO:0004842)
0.0	7.5	GO:0005198	structural molecule activity(GO:0005198)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.9	12.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.8	39.6	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.8	41.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.7	50.8	PID P38 ALPHA BETA DOWNSTREAM PATHWAY	Signaling mediated by p38-alpha and p38-beta
0.6	42.4	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.5	12.8	PID ARF 3PATHWAY	Arf1 pathway
0.3	16.3	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.2	12.7	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.2	8.5	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2	19.2	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.2	5.6	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.2	27.0	PID SMAD2 3NUCLEAR PATHWAY	Regulation of nuclear SMAD2/3 signaling
0.2	51.9	NABA ECM REGULATORS	Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1	18.5	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.1	3.3	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family
0.1	8.7	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.1	5.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	27.7	NABA ECM GLYCOPROTEINS	Genes encoding structural ECM glycoproteins
0.1	4.3	PID IGF1 PATHWAY	IGF1 pathway
0.1	9.9	PID IL4 2PATHWAY	IL4-mediated signaling events
0.1	4.9	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	6.0	PID ATR PATHWAY	ATR signaling pathway
0.1	4.6	NABA CORE MATRISOME	Ensemble of genes encoding core extracellular matrix including ECM glycoproteins, collagens and proteoglycans
0.1	4.7	PID BMP PATHWAY	BMP receptor signaling
0.1	5.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.1	3.8	PID P53 REGULATION PATHWAY	p53 pathway
0.1	1.5	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.1	1.6	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.1	1.8	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.1	1.6	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	3.6	PID REG GR PATHWAY	Glucocorticoid receptor regulatory network
0.0	0.8	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.5	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.0	0.9	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	3.2	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.3	26.6	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.7	33.2	REACTOME AMYLOIDS	Genes involved in Amyloids
0.6	12.2	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.5	9.3	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.5	27.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.5	28.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.5	18.5	REACTOME TIGHT JUNCTION INTERACTIONS	Genes involved in Tight junction interactions
0.4	6.6	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.4	6.2	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.4	5.1	REACTOME HORMONE LIGAND BINDING RECEPTORS	Genes involved in Hormone ligand-binding receptors
0.3	9.3	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.3	4.9	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.3	3.9	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.3	8.0	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.3	13.3	REACTOME COMPLEMENT CASCADE	Genes involved in Complement cascade
0.3	7.3	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.3	32.9	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.3	8.5	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3	7.5	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.2	3.4	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.2	8.0	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.2	5.7	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.2	13.4	REACTOME COLLAGEN FORMATION	Genes involved in Collagen formation
0.2	5.0	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.2	5.5	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.2	3.5	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.2	4.0	REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI	Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.2	6.7	REACTOME EXTRACELLULAR MATRIX ORGANIZATION	Genes involved in Extracellular matrix organization
0.2	1.6	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.2	2.6	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.1	2.8	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	3.7	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.1	5.6	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.1	2.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	1.5	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	1.9	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1	1.8	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1	3.0	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.1	3.1	REACTOME GLUCOSE TRANSPORT	Genes involved in Glucose transport
0.1	7.9	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.1	2.1	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.1	1.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	1.0	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.8	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.9	REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA	Genes involved in G beta:gamma signalling through PI3Kgamma
0.0	3.0	REACTOME DOWNSTREAM SIGNAL TRANSDUCTION	Genes involved in Downstream signal transduction
0.0	0.7	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	1.0	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.5	REACTOME IL RECEPTOR SHC SIGNALING	Genes involved in Interleukin receptor SHC signaling
0.0	0.7	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
0.0	0.4	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.3	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	1.7	REACTOME RNA POL I RNA POL III AND MITOCHONDRIAL TRANSCRIPTION	Genes involved in RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription
0.0	0.3	REACTOME IRON UPTAKE AND TRANSPORT	Genes involved in Iron uptake and transport
0.0	2.9	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.0	0.2	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1

Results for FOXA1

Z-value: 2.00

Motif logo

Transcription factors associated with FOXA1

Activity-expression correlation:

Activity profile of FOXA1 motif

Sorted Z-values of FOXA1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA1

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Top targets:

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: